<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN3</accession>
    <name>A0A6A6NLN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_405364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLN3"/>
    <dbReference type="OrthoDB" id="5317242at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025378810" evidence="1">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="226" mass="23919" checksum="0FD3D6C9F87E1987" modified="2020-06-17" version="1">MARLLALLGLASLPAISALVMQPRQSVELRWLVTTSSAYQEGVSPLPDVQALTLVPTGNATAPWALHPVPAGSVYPSFLLYDTKVATAAGNVCSAAACRGAQLAGLDIAWTEPPSEASPREGGSGNFYFNLVGPTEPVAGRVGAANIKAQGGWTQDDGHLLAIARGTDEEIASGAFWWDYGSWTLCNDGQGTSIITYNGTDPSCESTFVQLLPHDPYQCYCYYCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM24</accession>
    <name>A0A6A6NM24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_375518</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2113814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000001">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000005">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000082">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.730:FF:000003">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.110:FF:000003">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="540"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="689"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="837"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="983"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1132"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1278"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1427"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1622"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1622"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1654"/>
            <end position="1663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1685" mass="190615" checksum="E84ECAD75F996F20" modified="2020-06-17" version="1">MSLPIKFTELLQLQQVGIQQNSIGFNSCTLESDAYICVRQQAEGSASPEVVIVELKNGNNVIRRPIKADSAIMHWTKQIIALKAQSRTLQIFDLEKKAKLKSTVMGEDVHFWRWFSDSSLGLVTDTGVFHWNIFDPSAQSPEKMFDRHASLTGHQIISYRVSDDGQWSVLVGITQQQGRVVGQMQLYSKARGISQSIEGHAASFGTVRLEGAPADTKLFTFAVRTATGAKLHVIEVDHQASNPTFPKRNVDIYFPPEASNDFPVSLQVSQKYKIIYLVTKYGFIHLFDLETAQSIFMNRISSETIFTSISNTESTGIVGVNRKGQVLSVTVDEHTIIPFVMQNPASAELAYKLASRGGLPGADNLYSQRFEQLLQAGQYQEAAKTAANSPRGFLRTPQTIERFKQIPQQPGQLSVILQYFGMLLDKGGLNEYETLELVRPVLAQNRKHLLEKWLNEDKLGCSEQLGDIVRSHDMNLALQIYLKANVPAKVVAAFADLGQFDNILPFAKRVGYVPDFNVLLQHIVRTNPDKAVEFATGIAKDENGPLMDLDRIVDIFQSQGLIQQATAFLLDTLSQNLPEQGPLQTKLLEMNLLNAPQVADAILGNEMFSHYDRARVAALCENAGLLTRALEHNDDPAAIKRIIVQTDRIPEEWLINYFGTLTVELSLECLNEMLRVNIRQNLQAVIRIAQKYSELLGPANIIDLLEKYRTAEGLYYFLGSIVNVSQDKDVHFKYIEAATKMGQLNEVERICRESNYYDPEKVKNFLKEARLTEQLPLIIVCDRFNFIHDLVLYLYKNQQFKSIEVYVQRVNPSRTPAVLGGLLDVDCDESIIKSLLASVNPASIPIDELVAEVESRNRLKLLLPFLEATLASGNQQQAVYNALAKIYIDSNNNPEKFLKENDQYDSLVVGKYCEKRDPNLAYIAYRKGQNDLELINITNENAMFRAQARYLLERADPEIWAYVLSPNNIHRRSLVDQVISTAVPESQDPDKVSVAVKAFIGGDMPAELIELLEKIILEPSSFSDNPTLQNLLMLTAAKSDKSRMMGYIQQLSAYSPEDIANQCIELGMFEEAFEIYKKQNNHVEATNVLVDHIVSIDRAQDYADRVDLPEVWSKVAKAQLDGLRVSDSIESYIRAQDPTNYNEVIEIATHAGKDEDLIKFLKMARKKMREPPIDTALAFCYARTNQLPELEDFLRATNVADVEASGDKAYEEGFHEAAKIFYTSISNWAKLATTLVHLEDYQAAVECARKANSTKVWKQVNEACVDKKEFRLAQICGLNLIVHAEELADLVKQYEWNGYFDELIALLEAGLGLERAHMGMFTELGIALSKYHPDRVMEHLRLFWSRINIPKMIRACEEAHLWPELVFLYAHYDEWDNAALAMMERAADAWEHHSFKDTVVKVANLEIYYRALNFYLQEQPSLLTDLLQALTPRIDVNRVVRMFEKSDNIPLIKPFLLNVQPQNKRAVNNAINDLLIEEEDYKTLRDSVENYDNYDAVDLAQRLERHELVFFRQIAANIYRKNKRWDKSIALSKQDKLFKDAIETAAMSGKPEVVEDLLRYFVDIGSRECYVGMLYACYDLIRPDVVLEVSWRSGLNDFTMPYMINLLSQQVATIDMLKKDNEERKAREATQQKEEDNTPILGGSRLMLTQGPAGGPPPPPPAAVSPAPYAQPNGIPAQPTGFRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM63</accession>
    <name>A0A6A6NM63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_358227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM63"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="222" mass="24503" checksum="1E9E8663C3B98F59" modified="2020-06-17" version="1">MAKDSHDFTYPSSLNAYAVSMRDYLSARPQYHHIVVGAIVFHSDRVLLIKRAPNDSRPNLWEIAGGSCDASDKSILAGAVRELREETGLSAARVSHHIEPDVEWVDRARRWLKVTFEVAVRNEGDPDGCVAVGVERTCEGGDSGSELRLETEGQSSRLGSEGEVAPPAGVFPAVRLDPKEHQDYVWAREEDVRRGATDGFALPFVSKAMQDTILEGFRLRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMN5</accession>
    <name>A0A6A6NMN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_375163</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMN5"/>
    <dbReference type="OrthoDB" id="342264at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053036">
        <property type="entry name" value="CellCycle_DNARepair_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667:SF1">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="WGR" evidence="4">
        <location>
            <begin position="199"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="374" mass="42002" checksum="DECCCA18F5A2B062" modified="2020-06-17" version="1">MKNPLSPFTIAISGDFGEARSHENVKRWIENNGGKYATAITKDTTHLICTREHYKRKVTMVKQAEQHKHIKIVTFDWLEDSLLSCTRKREGRYLLQKLLKAEELEKKIKKAAERRKAKQEVRIFNQGVRKAQNDLGSSKPSRSRAKPNTAQSKKTSGAKARVTKAQPSSLSLSAAPMAVRTSNLLNGPGPNEGDFVPGNHHIYRDPTGFDYDIVLYRIDIARNVNERFKIRIFESNHRPPSYSLTTTHLPLPPTPPSPPTIDHPINTPFEPVFATFQSIFLAKTGVAWEERLTAYRARLNCRAAGQPWRPGHFGDSAARAMGEFKTSNAGCGGDDSDAEPWLYGPPTGNKPKGLMPDMGVRKVNSWSEIKEWDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNQ2</accession>
    <name>A0A6A6NNQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_293065</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNQ2"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF3">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="515"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="544" mass="60300" checksum="15D24928E2642B95" modified="2020-06-17" version="1">MALAKHIDPDELLKTLKHSSASSRGKHTKLGTSHVTPYTTKYASTQEIPKFRMPQDSAPADVVYQLIKDELDLDGRPNLNLASFVSTYMEKEAEQLMVENLAKNLADADEYPTLMAMHSRCVSILANLWGAQKGESAIGTATTGSSEAVHLGGLAMKRRWQEKRRAAGKDASKPNIIMGANAQVALEKFARYFDVEARILPVSEKSHHVLDPEEVRKNVDENTIGVFVIVGSTYTGHYEPVEEISKMLDEYEEASGNDVPIHVDAASAGFVAPFAHVQAGGMKWNFELPRVKSINSSGHKYGLVYPGLGWAVWRDESYLPKDLIFELHYLGGTEQSYTLNFSRPGAQVLVEYFNLIHLGVNGFRQIVENALSNARLLSRVLEATGWYQCVSDIHRQKGHFGYDAGKPPFEGGDSSAEYNPGLPVVAFRLSDAFKKQFPHVKQAAVSNMLRMKQYIIPNYELPPNEGKTEILRVVIRESMAMDLIDRLVSDIASVTETLMESDVLDLAGWQPFSTSVEKQHSSRGVNDGKKGSKPMSEGIHRSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNW5</accession>
    <name>A0A6A6NNW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNW5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025343260" evidence="1">
        <location>
            <begin position="33"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="85" mass="9341" checksum="B0B15BA09A93D4AE" modified="2020-06-17" version="1">MFMGSPYVINGLRVGLLTVFICLLGERNVGLGMEGSWVDGLSGLRDRKGSLALRLWSRGGDGMLLFGLWFSWLLDMAREGNEGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNX8</accession>
    <name>A0A6A6NNX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_356055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNX8"/>
    <dbReference type="OrthoDB" id="250802at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2950:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="F1F0 ATP synthase subunit B, membrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="114" mass="12885" checksum="32E0219831271DFA" modified="2020-06-17" version="1">MSAQNSIGIQTLLDAEREAQKIVQKAREYRTKRVRDARSEAQKEIEDYRKQKEGEFKAFENEHSSGNKKAEEEANKETEVKLKEIKQIGGSKGGKVVEDLLTAVVSVKPEPPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP52</accession>
    <name>A0A6A6NP52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_401501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP52"/>
    <dbReference type="OrthoDB" id="5307922at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF30">
        <property type="entry name" value="SERUM PARAOXONASE_ARYLESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="452" mass="49067" checksum="E8ADF9B7CF701466" modified="2020-06-17" version="1">MDSFNMENAQQMLDFAKANLLLVGIFALFFVGMIISKNVYDRLMHFTIFVAALGALNDFALAKAVQERYFNVRTLYKNSLSRLEKVDTFPTKAVVYADQIRNCEDIVLNEDAGFAILSCDPTRDFWNAVMDIRISPNGTGSLYLWSYATSPPSLRPITFSDFPAGTTDFHPLGIDYDAATSTLYAVDHARSGLRVDVFRLDPPTARASLLTTLADPTHLRTPNGVAALSPTELLVTNDHFFVSDERPWLALLETYLSLPLSWVTGVRLAPDDTSAAGGAGVKPAYGLAADGIPFANGIARLNATHVVVAACTRPGLYLYSLAEPAEPAPPKLVFERYVRTPVMVDNVSVDSAGKVLFSGHPDAAALVNVSKTNHAFDLDAKGEEGEKAREGRPRSGSWVGEWDPVEGTLRDLFVDDGTVYGSSSSAVRDVKRGLTLVVGLYERGVLMAETGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP58</accession>
    <name>A0A6A6NP58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_292890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP58"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF416">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE GODZILLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="422"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="364"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="501" mass="54484" checksum="FBEED90FD3A1CAD7" modified="2020-06-17" version="1" fragment="single">MRSCGDWSAPIRRHECVQFLLLPLRFARPLHPLANHRASSPSPIAGAEGLDTFTLVFPDPDWQQISQDDFDKVDVRHRANASISFEYAKNGGIRTLSAGDASPGDKVSGLLYVPLLASPSCESAVAPFIPPNETRRSDLPRQDYDLIALAPWTSPRCTLEFLDHAHENPFTRAFLFYLPDNRTDTPPLTNDPVWSLGDGGQWKSDNKYPVYALPGLTGAIMMNALAQYSGNLTTVPHGHELANYYHPSAYVRLFSIVDTGSGTTMPSLWVFLLIVLGILIFIIGLTSAIMHWLQRERRRELRRRVANGEVDLEALGIKRLTVPQELLGKLPLYTYTVSGVPPAPEPTAAQAAAAAPPPYSADGTADSPASPLTAATTPAATAAAVAAAAATTTTSPPASPSRSDAPPSSSSNRSPQFAQPTCAICLDDFEPGVSQVRELPCQHIFHPDCVDPFLRDNSSLCPLCKKSVLPRGYCPTTVTNAMVRRERLLRRIRERVAEDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPE6</accession>
    <name>A0A6A6NPE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_356952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPE6"/>
    <dbReference type="OrthoDB" id="4177236at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="173"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="395" mass="44936" checksum="321CB8219298DFAB" modified="2020-06-17" version="1">MPSNDGGREKEVEEQAENKLELLNRSMISKATQIVSDNKPASDLWPQFRQALSDYKRRRTDILDSQNPKPEPSGEDPRCGSDSKPKAGLERHDSFKHKIPDEDIYTPWPLSSALQNSLQITAVATGDVIQNEQASMLRSILSTLLIQGELLYQYATRTVVRIFSDMVVKINKSKDQTETHVLHHIHKHTQRIPAPRPLGMMVIGIWSYTFTSFIPGIPLDRIWGNLTPAKKSYVREQLNHIFTELRRLPGPSSEGYLGGGTPPVCKGGHRFRKTSSSPIVSEAQFNDFLLEDSWLQPARVDHIHRSLPNGHRIVMTHGDLCPPNIIVESEDRQRITGIVDWDTGGAYPEYWEYVNAFKSSLGTRDDWRLYLPKAGIGRYFNEYARYSVIGRFARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPL4</accession>
    <name>A0A6A6NPL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_128921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPL4"/>
    <dbReference type="OrthoDB" id="7491348at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="182" mass="20304" checksum="554B56050373F7D4" modified="2020-06-17" version="1">MDAAVRCGAVRCGAVRCGAVRCDDDEGDVVDHAEAGMEGEEPPRCRYALARFRSLFFCFWFFILKTLKRYCRFLRFTCSASEGQGKHLPIHTCNSILAAKGGREPAWSGRWGTWNARGTCFVGLLVQWKKDEAGPSSLGDLVPLVEGYYCRLFPCLIPWRSSAIPGVDRSDRTCTPFPSTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ52</accession>
    <name>A0A6A6NQ52_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_354445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ52"/>
    <dbReference type="OrthoDB" id="2142759at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="158"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="409" mass="46265" checksum="E7273BF84142E10D" modified="2020-06-17" version="1">MALPLPALTGRDGTTRQIPILAPVEDSTHSSMTHNVILFLHPGYSPPLNVLFSLPCADRVSESGVYGVHHRTALTACQIIANNAFTGFLAVDAKGESRIDETIGPDEILTGREYFFVVEGDVRYPVVPSFRDWEFPHHRVPDFWPHIPPAESLYNDVCLVTKFPWAVTKSHIVPSIEKDWFNTNCMWRYSNSIVPDIDDVKNILLLKMDLHFCFDRFMFTFVPKPRASGTSSHKEATEEALSYTLHVLAGDQALFASLHHDIQLPHLRSVAAEYLFARFALAIFIGIKPFVNAGYKRRIARFMVVKDSGGPEMVVEDIDGQVLQSRYDGGKGRSASPSKRKRADEDTMEQQEDGETAVDEIDEPALQEKDTNDAWYADVLDCEQVRGRPTKRQRALYQVDDYFDSRSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRJ2</accession>
    <name>A0A6A6NRJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_400450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5423926at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="834"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1172"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1207"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1292"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1374"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1394"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1525"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1577"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1600"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1619"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1635"/>
            <end position="1646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1735" mass="181571" checksum="7F5A5B8C4A196E08" modified="2020-06-17" version="1">MFSRRRRASNPHLAQQPPTPSAALAASQAFLSSRPASSSSLSSAAAAAALRSHPSSPEPVGHVTTKRMAARRRASVSSVGSGGASAADRERAPGVGGGGGGGGARATSPATATPGRPNLARRGSTSSMSERTFRRSPSPSASASASAAAAAAAPRSRSHSPLGAQPPLPAPREEEDEHADAVPPVPPVPAEFKAGTGPWHKRAASAEPQGASPKGPGAGAEFGARVASPPPAAPGKTANGRGRGRGRSVDSAATAAAAAGGANISPGKQQGRSGWFTAPVGSGSATAATSQFRQTPELRVDGGAGARVGHAQRDAQRRVQEAQEKPVQQKRKKKKDMAEQGEDGGLHPAMGSEWGGGYKATAERKPSPHPLKADAREEEPTTAAATPPEQMHEERGDSVADTAAVEPKSILPADANTSKKLESPHPQTPAPPAPSKDVHRSTSSAASPTRTPNSAQPAPPRPRSSSHPVQPAAKAITPDGHPHDPSSSLAAPASADRRERPTSLSPSRSAHFSARLVDLETVRHQPPPRSFSPVKSALKHSPSSAGGAGAGAARTGSPSPRARVTGGSEDEDATAATTAGPRKKGARVSFDEDALVVGTAAATEGRGGAESGKSEEDDDDLDELMKPRPTLPSFGSIRGRGPRRVEEVVEDEEDDEDDEDEVTRQQQHRQRRQMPEKVTETVPPPHSSMASPASTIAEREREPSAALGSSSDHAVGAVLAKDYAEKQHRRDDAAGERAQQNGKAQLPLPPEVTSVEGPGYFSDEASTSEASSTVAGEEAEPELEPEPEPVRAVESESESEDEDEDEDEKKHKGVDIPTPISEGVEEEQGLAGEKGGDAYDKVERTVCERDTEEKRPDIPAIAISPASPEQPAEEDRPEYVMPGGFPEGNEAEETPEKESTEREHMPGEFPGEFWDEDADQEETQASSRAAVDDGQTASQPPPPESNAPPSVPEKRAALTAAALAPHEEEESSSEDGSSIYSDAEDHFDDEPANFASLDAIIESPMLPPTAPKAATGVATPPDSPSTKLGPGTAEEASPRDTQAKNGDWDEAKAYWSGLTEQRKREIEEEAKRHAREIAAAQPKEEKPKPKPKTKKKKKAVKPVAAPATAPAVAAVAAPAPSTTPEKPESTAPAPKQQRKKKQQTAKPAGLQQSRHAVPEHTTAPPAPRMRKSMRDKDALPQRQEEPQPRAADPVPKMRTSMRDRQPKLQQQRPTSPQQHSSGAHLRKSMRPSTADDAQQHQRQRPRGLLTSRHSDDGVSGPREPRGALQKRNIPAVPPLQAPAGPPTTSQQARPATSGAAPASAAERKRFSAMAALGGAPALHPDGNDSDASESSFRRERRRRRRTADASAPISMRRTMRGGPQPQSPSGAASRGRDVSPQRGEARGARRFSIRSLSPAGSATSMPGGGGRMRTSLRTSVDSGGSPKRTFPGFGGIKKKAGAATSGGGAKKGAAGVGAKFKSRFADSSDEDEDEGGRPGERAVFRSRFAADSDEEDDAASQGPSSWAMPKDLTPVRGIPRRSGVEDGESTDLEEEDEDDDEESGVDDETRPNAQAKAKKGLNGSIHAAGAAMLANGRRKEEEDDKAKREQAASPSPAGHEHKKKRRGFFGLGKKKNKGEAPAAAPDETASAEPAAADRTRSPRGESEPPSGPARGLSDSWASGGAAQRQQRPSGLLRRGTSGTLETVGTAETVGTAPAAMGGGEEAGEGGKKVIVDRRGKKKKFQGLRRVFGLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRU3</accession>
    <name>A0A6A6NRU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein required for hyphal anastomosis</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_352876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRU3"/>
    <dbReference type="OrthoDB" id="18234at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012486">
        <property type="entry name" value="Far11/STRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07923">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01293">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01292">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP N-terminal" evidence="2">
        <location>
            <begin position="153"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="3">
        <location>
            <begin position="582"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="838"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1057" mass="119642" checksum="13ECF3D82E6A2356" modified="2020-06-17" version="1">MDSQSPDANFSEDSMPRVPAAVDEAEMMSLPTDMASSNNDPIAGRDGEDDLRTPLDTVEQEGFLPTADTGASTSSGATGHKPALPTDRVSLPTRPSLRRDKSVPSSPQQLPPPPAPIPPPSQQQPHMDPGNPENSLSLMQFRRLVAEMPKVEPTPYAFEYTDASSMPEELEEWFTYGVEERARVFKTLISFKGEWEEYHDVWAMVDGPYFKGKMDWSKADEAERATFVERLLRRVHDTNMAVRLTNLEALTYLMFGAYQETAGADRESTAPADQADGGAVHSAYRTSPLQIQWIRRNAKLIFNASGLQTIYDIMRSACLRECMTSMDQDSKDGREEERREMWCAMTIMYFFLEAARTDCEEGVDSELRDGIITLQPQIMTFLMDIIARLRWDESIGLPLMKILLLLWKSILVVLGGITDVDRTKASFRDETLETEDRRGQPLITASPLDYHLFRQEISSKYPAYNPPPPLFPLEPENNSILPPLKNHPSKATGSNIFGAGTTQTGTSILHQPVHIATPVPSPPPSPAGPGGKGGKKHNYQTNQLFPFMYPPLDESSNNLGGKGSTDLQDILVGRKWKGSDIPASILEAAELFAKRMRATRAMKQLWEERVEFMKYERGWSASYDEDVEDLDLSSDLKSSSKGKGKVGRLLSTDIETRLKAVEELYKTSLPHLQSVVIVLLKVVLSNVTSLITQANGSNGLQGPFQFHDGQNGNLSRQDSNLNGNHPDIPSPSTEELDAMRSQEILAKAVSGILILLLKWFKVSHILKFEYLTQLLLDSNYIPLILKLLQTQELERVVNYKCDREDINFFQYCLSHSRHRPRQKEEEPELADSDSDDAAPPPIKRQRSPPPKAPDPPQQAYLHPPEVDDLGKPMSDFPPEPITNFSWRNFFSSINWLRVMQKICKNKAHRNLLLVQYKSSGYLKKSLKVPQPLLRLYALKLFKNQVPYCGRKWRQSNMRVITAVYLHCRPDLRDDWLAGSDVDADVEESVPLEQALRALTHWHNLKRYPEMMGAEKGILEEEQDFFVRELEKMEWAEESMPPEEIPEQWEGQMHMEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRX8</accession>
    <name>A0A6A6NRX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Retinol dehydrogenase 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_291306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRX8"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF33">
        <property type="entry name" value="OXIDOREDUCTASE BLI-4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36662" checksum="14D9E96149371359" modified="2020-06-17" version="1">MQAVKTAVAENLRGTGNALVETTKRFSLKDVGTLEGKVAVVTGGSEGIGYGCTYTLLTHNVKDLFVLSKSQDVVEGALEAIRDELGDSAAQKVHWLQCDLSDWKATRDAARKIARMTDRLDILINNAARGIMTRQFAPTNGIDLHMASNHMGHVVLTSSLLPLLKSTADLGHTVRIVNVASNAHQSAPSDVRFDSVSELNRDYGPLPQYGRTKLANILYSRYLARHLAPRHPNILVNATHPGFVETRQSSEHIMEPYPLGGYAMKVGMAPFKKDQFDGAVSTMFAATRTAQSGEYICPPAVPEEGSALANNEELGERLMKLTKEVVEEKAGGTLDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS06</accession>
    <name>A0A6A6NS06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">MICOS complex subunit MIC60</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mitofilin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_353557</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 13">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MICOS complex subunit Mic60 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS06"/>
    <dbReference type="OrthoDB" id="10261039at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019133">
        <property type="entry name" value="MIC60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415:SF7">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415">
        <property type="entry name" value="MITOFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09731">
        <property type="entry name" value="Mitofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="159"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="313"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="388"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2454287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="620" mass="68119" checksum="C398AC265D1CBA13" modified="2020-06-17" version="1">MQQRTQQRWYADEKKPEQTEQTPPKPDATMPPTGTAKASTGPSAAPKKKKGRIRRFLLSLFVLSALAYAGGVFYSLKSDNFHDFFTEYVPFGEDAVAYLEEREFRRRFPGKGPDSRLHQQVRGENKITIPSKSGLSWRIAKDEEEPQEGQDLAVKGRHLSAIDDNKPMPSQPSPLDKQKDADARKKEEVKKEEPSSHALLPKNEKKPEEKSKPEAPAAPPPAPAEPAAPSSPASLIDASSIPENAEPTIQEVVTMLNSLISVINDDNAGGKYHGAITAAKERLSTVASSVSSLKSSLQSEADAKMRKTESEFDEAAQKLVRRLEADMHDLESRWKEEYESEREKLANSYAAKLKAEIDAQKSVHEQTLKNELTKQAIALQRHFTDSVAQRVEQEREGRLSRLAELETEIRALESLTKDSESVIDRTLQTQHLQVALDAVREAALDATNTHPQPFVTQLAALKEVAAADPVVDAAIASMQPQAYQRGIPTPGMLVDRFRRVAAEVRKAALLPEDAGVASHAASVVLSKVMFHKGSPGTTADPAAGAKGLPVGEDTEAKLARAEMWLEEGNLDAAAREVNTLNGWAKVLCRDWLADVRKVLEVRQALDVISAEARLQSLLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS90</accession>
    <name>A0A6A6NS90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS90"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025679092" evidence="2">
        <location>
            <begin position="17"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="376" mass="39919" checksum="324D4791A7D039B9" modified="2020-06-17" version="1">MHSVSLLIAAAIAANAAPLSSGLADRAVERAAAPAVGNAWLSPAELDDDGNSLDTRDSTVGNTWLVPAEVAEDESLDTRDSAVGNAWLVPAEVAEDESLDTRDSAVGNAWLVPAEVAEDESLDTRDSAVGNAWLSPAELDEDDSLETREPQIPPSTWLAVAEEGDYDEDLEARDPQVKLPTPNAWLATAEADDYDEDLEARAPAKAAEAVAEPAATPPISATWLKLAMERDYPGFGEKAKRDVTEEEVKDLKPRQTLTFTPGPVPTNGPGNTPSAWLKLAMERDYPGFDPKDKRGPAGESRWIPVEQKHGDVLKAKRAASAAPAGGVWVPIDEASAAGAAEIARRAESVGSVWLDINAAEDDTADVSERDVSSDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSY1</accession>
    <name>A0A6A6NSY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl hydrolase family 85-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSY1"/>
    <dbReference type="OrthoDB" id="284473at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033925">
        <property type="term" value="F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032979">
        <property type="entry name" value="ENGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005201">
        <property type="entry name" value="TIM_ENGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246:SF1">
        <property type="entry name" value="CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246">
        <property type="entry name" value="ENDO BETA N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03644">
        <property type="entry name" value="Glyco_hydro_85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosolic endo-beta-N-acetylglucosaminidase TIM barrel" evidence="1">
        <location>
            <begin position="121"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="753" mass="85205" checksum="DA4C7999D36DF663" modified="2020-06-17" version="1">MAACGLKDILRPIRDDLRDKLPHFLRPKDPPEPVPDLEKQREDALRGFAYFETFDQLLQWSAADVEPLQQSNTPLVPRPEITDPRLYPRSSKTPVPAKVVLIHDYSGNYHAYENVQTIGCEPERYTCQYLQFVDSLVYFSHKLVTIPPASWTNTLHRNGVKSLGTFIIERCQPETERMFTMVPSAKNANELSFLVANQLLKMAEIYGFDGWLINIEKPFPRHIWNPSTMVRFLDQLYSDMRNVLHTNAELIWYDALTVDNRINYQNKLTKKNIPFSQACSATLTNYKWKEQDALESKKMAEGNTVSSGQVVMGVDVWAQNARNKPKRVTYPSDNGGGTNTGLAVWKSATYKLSSGIFAPAWCFQHFPIPAQHRAVERAMWDGDELPSDLCCDCGTTKRHTFPAGWHAEHPITKWAREFPAGAVDFFYTDFASPFMQHDVALKYAFYDGMAAHAQVGSQSILPHFRTLEGLQQTLEHSGGDTARILYGTIDDSEPRALIWAYSQTGTPPPRYFKLRLFTLNMLADGTLRARINFLPSPWLLKADIGFYVTISGDEQRFPIKTTHARGSSHGSHVLMFPVGDKNVGSGGDRLEELGVYVHSSVFGVRNWSTPGLEDRARCMSILQISNIAITRLASQESDGELPFDIWLFDKRGEDGRRLERLTWLLRLKKGHRFDPNTRPAYQQSALTGPFAYFEVLWEDLVIGRSYAMEYVVGDKLREAVASVQGGLMRIGLVGVGFAGEKVPGVWHNPLLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTM4</accession>
    <name>A0A6A6NTM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_290136</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTM4"/>
    <dbReference type="OrthoDB" id="9439903at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF12">
        <property type="entry name" value="RFEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="876"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="878"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="891"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="905"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1054" mass="113663" checksum="82EEE0DE8DAF5E13" modified="2020-06-17" version="1">MDDSLTSNGISALSASQHQHNSLGQRYFGSQPSPSTLPPLHPLPKNTRQPNTAPQTPMASHPHTPNPPQHLGGQSTSYPPIAPQPSQPPPVPMQPSTSYLQSGPPAPQPFLAPSSTSHPNQPSIAPAPPSRGLPAPITSHGGSGYATQYGQSQLLSQPPVVPTNQDMEPVHVVGSQGRRGVLPSLPGRSVAGTGKTAPVPTKNADGKYPCPHCNRTYLHAKHLKRHMLRHTGDRPYQCPLCSDTFSRSDILKRHFQKCSARRGNPTGATHLSHSQSHLRRNSAAVSSAADHGFIGNVSAPSSAYGDGSPVNGLAGVGLPSEHAVLPGQLASSSARSSRSNSLMRPAGSGKENRRSLPNMSALTSVGLGGFDESRAVSAAASGGMPQPMQAFHTPHGLAQHNFAYQNPAVNGTDMSHGPSVKSEQHDMLYYGRPPMQNLEGVHGGPGENVEWGDSFQSDGQDGFMMAHTGAADSMAGGKGGEGGGVGSGNFQPAGESTQESMFGNMYPQPSQFGADPHFPWNLDPSAHDDPMQNKADALVAFCLPKGTQPSNHSLTTGELKTIFTKDNAIEFLNLFANWQSHWPMIHIPTFNPYASNDGLVSAMMCAGAVYSDRLSVHQVRKLINTVKDAIYRSSRVYNFVAASYPDCPLGAFGHVKPDIEEIQSLILLLSLLMWHGNNAQRCVAMEEYPKVAIAARMAGLLRLAPPNHPAYSILHQSDRALDQTDASSWQWEQWTEQETRVRIMYLVFLIDAAMAIYFNYPPSFDICELQLPLPADDATWEAATAADCADALGLHGPEFQIDKNTTGSRRPTQMNLNAVVAMLMDGSYKYGERLTNPYSKFIVIHALHALLWRCQSSIATGSGQITITGYAVSGPGTPLSQNEWPTDNHSGSRGSATSGAATPNEGGNTQLAQQTQNAHHLLKRVALALENWKAAWDGDMMVQYPPTYRARRVGFCRDGIYFYWLAIVLLRGPNRQAETQLPPDTRCFRMFQYIKKIKVHVAMESGQRGLDVGSMGEIDDSYGVEDLTLDMKLLFAPISSTTKHGGFSPTRGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTR4</accession>
    <name>A0A6A6NTR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_373712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTR4"/>
    <dbReference type="OrthoDB" id="3921198at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="293"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="844" mass="90113" checksum="AB6FCD932D228288" modified="2020-06-17" version="1">MRMDSTSNHDLAIDIMFGGLDSSSHHSPSSSSRPICQPLDRNFLSPYHAQFSHNPWTPATEFTDNGIFEFEAESLYGNKDEQSRQSSYFPPLLPPPGCSDIETSTTADLESECLPVPDAQPYPSEPLGNSLSPNFPHFDISMFSSMSDTSLACMQGQNAGSLDMLSIENYNYPTELNPQDLNSKELASSSGSPSKQKQQKQQKQQQQQRHEQRRQPTTTSKAKSTSSERKAAMIASETNTVNKSFQFVEYCVKQGDKIPKPRMEGGVKKRPGRSGPLSPVQREHAAAMRKLGSCDNCRMRKEKCDPGIPCKACITHYKADLTSVRCRGFSLAQLADGLVSERLAWHPKARSLESFLPAVRFGVYDKSVVIPLNFGFGPSMMVRVRVVRVPNPQVHLVHDHLLYEWPPRPASRTFREPRQQSVFPAVLEDTTHLVDQLDQHIDLLVREHIHQFPLYDTGLKVFEGICTLALSQRQPQHRDLLVTALKLITLVHIAGDITVPLADPTVARIIQYTKTPAFPAPPGSVSTSFASPPPNPALYAATANSGAPPAHEAPTPCFIRGQLGGAFPALARRLQTALLDGLEALALSRACEHFPTIVAAVAAQLMAVETAQYHAAKRGYHDALDEAGGVPMSASSSNSSSFSSSSRSSAASGASSFSSAPPASGRGVAARPRPSCAPAAAATADVAAFSDDAVDKLLRFYRTCYGGCHHNGLHVPGCETAASAAAGPAHSACNSSPFSALGSFAASAAATGGCYSSGSACGSTAAAAAAAALAGSTAASGLSRAAADPGARFVVQMKKAVSESRAYLAGQRKVGVSDVGETLSAYFDRLLARLFIPELGRVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTT9</accession>
    <name>A0A6A6NTT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_80897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTT9"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="35553" checksum="9EA567A767BC3C02" modified="2020-06-17" version="1">MTDSVPQEYKDTVDIHDRMFQKISVDRRIYCVPVDEEEEERLILQNQIMHYLFEEKLYFPDIPYPDKVLECGYGRASWAVQMAQTYEDCEITAIDIYPADLPDEPDNLECELWDLNEPLVPTYERNQFDLVHSHFVAPGIKKERWREYLKDLVRLTKKGGWVQVAEFYYTIQSDNGLLGEDDALYKWGVNYRAAVQHDRDPRVGNYIDQLLRDAGLLQVQIRHFRLPIGGWPEDPRQKWIGEQNLTNVNQMLDSLALYPFTQRLGWTPAQVKELTNQARAEAAETRRKLYIPLSVAWGRKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTZ0</accession>
    <name>A0A6A6NTZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_272412</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTZ0"/>
    <dbReference type="OrthoDB" id="3366546at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11020" checksum="15BCDC8A613FA612" modified="2020-06-17" version="1" fragment="single">MDAAAYLKGQGWRGLGYSLDKQDRGIARPLLVSHKKDGLGLGKQKAGHAVSSDQWWLQAYDQSLKNAGTGKETALSQLSGKNANKPSLYNFFVRGQGLQGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUC1</accession>
    <name>A0A6A6NUC1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_96014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUC1"/>
    <dbReference type="OrthoDB" id="2427554at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016287">
        <property type="term" value="F:glycerone-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="57"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="670" mass="75265" checksum="117541C73B1CC6C0" modified="2020-06-17" version="1">MNQQPQQQQQNQSAPRYRLIPAVYDLGLWIFSLCLDIFFREVYPRGAWRVPNRGPVIVVAAPHHNQFVDSILLMRILKRHAGRRVCFLIAEKSMKEPYIGPMAACMGALPVVRAMDNVKPAEGKIYLPSPEDDPTLVRGEGTDFTDKEFMIGGTIYLPKVGKESPEQQAIAEILGPKELRLRKPFKEFERGHPLYDGLRKGTEFKIAPHIDQGQMFDAVYRELHNGACIGIFPEGGSHDRPNMLPLKAGAALIALETLAKDPRCGLSIVPAGMNYFHPNKFRSRAVIEFGHPVQVHPAQVEAFKEGGASKRNAVGSLLETIQEALTAVTQQASDHETLMLIQATRRLYKPMRMKLPLPVVIELNRRLLKGYTTFKNEPQVIQLTNAIQSYNRRLRALGIGDHQVEWGNVKQRPWWLVLMTLIYRIGELLTLLAGALPSVALFWPVFVAAKVISVKKQRKALAASSVKLEARDVVGTWKMLVAVGLAPALYTWYTVICSLWLHYCRQDGHYCAAVAPWWLDARTYVPAAVPLSGFAFFFFGLMISITFAGLRIGEIGMDVLKSLPPLLVALNPRSADQLVRLRQQRQAVSRQVVDVINTFGPEIFPDFENERLVVGRYEEEDEEEVELGGDAYESQLKNMLGDRDEGDFETGDGAVAFVKQDTDVENKKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUH7</accession>
    <name>A0A6A6NUH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Tyrosyl-DNA phosphodiesterase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_416409</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUH7"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09194">
        <property type="entry name" value="PLDc_yTdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000038">
        <property type="entry name" value="Probable tyrosyl-DNA phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="11">
        <location>
            <position position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="598" mass="66024" checksum="B6C8249B84994407" modified="2020-06-17" version="1">MEGEDEPYPRLAKRVKLEKGKDALPLASGSGSPTREQTRSPLTSLGRAVTPPPPRLKSDAGRTPRNDATRQGKAGTKVLPSPFSLNRVADLPDMCNVDAVGLRDILGDPLIRECWQFNYLFDIDYVMKALDEDVRNMVSVKIVHGSWKKEDGHRVMLEESAKRYSNVQLITAHMPEAFGTHHSKMMILLRHDDTAQIVIHTANMISQDWEGMCQAVWRSPPLPFQKNTDKQPESAIGTGHRFKTDLLGYLRAYGGRLKSLVEQLSKYDFSSVRAALVASVPTRQPMDPRKSDKGTSFGWVRLKEVLGCIPVRPGPAAEPSPASLVTQISSIASLGPTDKWFKSFTDVLSATRDPPKCLKALTTASFKKPRGSSTSPTHEIIFPTPDEIRRSLAGYVSGASIHMRLQSAAQQKQLAYMRPHLRYWAGDGAVANAVRASAAGVQGRALRRRIAPHIKTYVRFADQRKEHIDWAMVTSANLSTQAWGNFPAKEGTDVRICSYEIGVVVWPDLCRGEGGGREEDVSMVPVFAKDLPEAIDLEGGESECEGSTGGKGDKVIVGIRMPYDLPLVPYSEDEVPWCATATHEEPDWMGRVWKNDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUQ1</accession>
    <name>A0A6A6NUQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_67089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUQ1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025354628" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10087" checksum="C8E06DD80F933C3A" modified="2020-06-17" version="1">MWPFSLRPLLLPPTAATARVVGGSSGSSSCRGGGSGTSGTASFLQRAVFGLFGSCKPHHFGQHPITAPRHPLASAPRAARPALCPSLSLFPSHLPSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVE7</accession>
    <name>A0A6A6NVE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_373501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVE7"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="322" mass="35832" checksum="8CE42779573D5AD3" modified="2020-06-17" version="1">MGVFGFLLRQFIARPAPIPEDVKLDGLTALITGATGGIGLEVARELVGHGVRRIILGVRDPQKGEEAKAELTRMDCVVEVWTVDCEEWKSTVAFGQRAQALDRLDIVILNAGVKKLKYSRAKTGHETNLQVNYLSTALLSLMLFVPLRATARRTKKPGRLSIVSCEVHLTPFRERSATKVLSHMNHKDTFTPFSPERYYTTKLLNVLWGRELSSRTDPKEVIVNVVNPGLCRTEIHRYEESHSFRLFQRLFGWNPAIGGHCVADAAVVADSDSHGAYISEMHVTEPSKFVSSTDGRATQSKLWLETMQLLRAEVPGAKLVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW27</accession>
    <name>A0A6A6NW27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_365407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW27"/>
    <dbReference type="OrthoDB" id="3546893at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="694"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="763" mass="80614" checksum="16C46CAF57597424" modified="2020-06-17" version="1">MGDNGMSAGAVAAVSVIGTVIFLALVLMIVLIIRASRSHKRLLLDLERRGFMLGQPFPAEERPSGVKRPQRALRRSSFFVYRPTTRWGALSSREDVGRQPPVENTDANDQGPDQKGEPRGECQSEIQSKQLNSLWPFNRISRIPQSILLEKLKKSRHSSAGQDPRPLPQSPIPLDPVTRSAAQSSEGLLKDQQRAVHSRMGSVTTLNDTAEEITQNRDSELVKKQSHMPSKSDCNRRTRANTIASVVGPIPPTSRIPRPDLPSRPFSLCSQHPGLAPNAPVPPLPLSIPNKTSGKSAAAFGRSPSGQSVSSLESVGSSILVSAAGSPARPRSPEARLKTGANPEWETSLILGPRPIRDTLTLRGRSNIYPAQSSARNSGTRFSLDGAHGNELSRSSRVNSTLSSLRFQPSNVRKHSAGSGSKPSRPASVSVPNSTKSSPRRYPRSRVTGSSSPARRRGSPSTVLRDTSGNQATPTRQGSQTSSQSSNGSPFKWDYLPLQSGGGKPSALKGSPGARKGHKRQNCVRISLAPTVMGAGSTGSRPPSNCMDGILEGPHAGTSAQETTTTTTGPTSPPNGGPFSGYVSLPPPSSAVFQPDLRLAPPPPPPSSCPRAPLTPNPRPLSPAAFDPDGLASPREPASRAPSPSSSPSSSPVRTKRHRHHRHHRRRRRRTSSPSPSLFSIPTFATLTPTSTRAAGSSSLPGGASSLTPTPLAPGLALAVVGPSSDKENTPPAGLADADARRGAAGVEDTPGSLYDGEGFLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH5</accession>
    <name>A0A6A6NWH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino-acid permease inda1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_288376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH5"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004762">
        <property type="entry name" value="Amino_acid_permease_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00913">
        <property type="entry name" value="2A0310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF12">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="28"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="530" mass="58034" checksum="2D9BFE80EF833875" modified="2020-06-17" version="1">MGCTPESFKRRTDADALNQLNHSLKKRHLHMIAIGGSIGAGLFVGSGSALSRGGPASLLLDFAIIGIMMFNVVYALGELAAMYPVSGGFYTYATRFIDPSWGFAMGWNYVAQWAIVLPLELTVAGLTVDYWEVDISVGVWITVFLVAIILINVFGVLGYGEEEFWTSMLKLCAIVIFMIIALVCVLGGGPSDGKFDEYWGARLWYDPGAFANGFKGFCSVFVTAAFAFAGTELVGLAAAESENPVKSLPGAVKQVFWRITLFYILALTFVGLMVPHTDDRLLGANPLIDVNASPFVLAAKDAGLIGFDSFMNVVILFSVLSIGNSGVYGGSRTLTALAEQGYAPKIFAYIDRAGRPLPSTILIIAFGCLGYVNLSADGPTVFDWLLALSGLSALFTWGSICLSHIRFRRAWAYNGRSLDDIPFHALFGVWGSWIGLLLVLLVLIAQFYTAVWPLGGGVNDAEGFFKSYLALPVVIGFWVAGFLWKRTGWLRTHQMDIDSGRREVNWAAIHETRKRHASWPIWRRFLSHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWS1</accession>
    <name>A0A6A6NWS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_365211</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWS1"/>
    <dbReference type="OrthoDB" id="10248446at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000004">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="25"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="28989" checksum="0C9B78F39F9C297B" modified="2020-06-17" version="1">MAAAQGSAISKRRKFVADGVFYAELNEFFQRELAEEGYSGVEVRVTPTVTDIIIRATHTQEVLGEQGRRIRELTSLIQKRFKFPENSVSLYAAKVQNRGLSAVAQCESLRYKLLNGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRAARAKSMKFTDGFMIHSGQPAKDFIDTATRHVLLRQGVLGIKVKIMRGSDPEGKAGPQKSLPDSVTIIEPKEEAPVVQPMSQDYGAKALAAQQAAEQARLAEQQEQGAEEPVEGYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWS5</accession>
    <name>A0A6A6NWS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_348150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWS5"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="14"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="211" mass="23819" checksum="9D56B6F539A14858" modified="2020-06-17" version="1">MDGGRRGGRRGGSVVVRVGDYHDLSAAGVECASVDGAYTMETLVHAGEPKRALAELFRVLRPGGRLALYEYDHDWCGEGKVGEEGESEEERYFRERMEVINRYAAMPGYAMFDRGVLPRLVEEVGFEDVVVRDLSANVEPMLRLFFILAYVPYLLVRMFGLEKWFVNTVAGVEGYRGRKHWGYIVVTARKPGEDPGTRDQSSFILEDKKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXI7</accession>
    <name>A0A6A6NXI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_287805</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXI7"/>
    <dbReference type="OrthoDB" id="3851628at2759"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.80:FF:000001">
        <property type="entry name" value="Dihydroxy-acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050165">
        <property type="entry name" value="DHAD_IlvD/Edd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002068">
        <property type="entry name" value="PRK00911.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000:SF5">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="17">
        <location>
            <begin position="87"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="18">
        <location>
            <begin position="419"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2456450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="623" mass="65871" checksum="4FDB9737E71704EE" modified="2020-06-17" version="1">MQLPPGQLLATSASAARRALLRRRWLAAPRAPFAAASRQSASLSTSAPRPKDDELNKVSKHVTQPKAQGASQAMLYATGFTERDMDKAQVGIASMWFSGNPCNMHLLDLNNAVKEGVAKAGLQPMQFNTIGVSDAISMGTNGMRFSLPSRDLIADSIETVMRGQWYDGGITIPGCDKNMPGALMAMARVNRPSLMVYGGSIAPGCASTLNNATIDVVSAFQAYGQYLTGEINEAVRSDIIRHACPGGGACGGMYTANTMATSIETMGLTLPGSSSNPAVSAAKRAECAAAGSAMRNLLKEDLKPLEILTRAAFENAMVVVNILGGSTNAVLHFLAIAHAADVPLAIDDFQRVSDRTPFLADLKPSGKYVMADVFRIGGTPALLKWLLGEGLLKGDVPTVTGKTLAQNVADAPVLPETQEVIRPLNNPIKPTGHIQILRGNVAPGGSVGKITGKEGTTFTGVARVFDCEDDFVTALEKESAKFVNVGPGGEKTKVVVIIRYEGPKGGPGMPEMLKPSSALMGAGLGQDVALITDGRFSGGSHGFLIGHVVPEAQEGGPIALLRDGDRISIDADTREINVLDVEEGWVEERRKEWTEPPLRYDKGVLFKYGKNVKDASRGCITDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXU2</accession>
    <name>A0A6A6NXU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_53197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXU2"/>
    <dbReference type="OrthoDB" id="5372703at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="273" mass="30764" checksum="30C828597DAF8B33" modified="2020-06-17" version="1">MHKTEASTKPKNLRANTRNPTEKFSYRVEKTENTRRTSVRLRKRASSNTPSSLDVSQKPSNQYEDQASTRQRKRRRNYEEKPPLAKRARTNVSAVSHRLLPLTAETLQSHIWLKRNNVDRDTLLERYLGILEPMGSEADNGGRSRGNKRSASRVGIGERSTASTGGDPETASQVIQKSSFTAAHYRNFILKGANISLQSRLVPEDIRTQISAIVQLEVSPRRKEELSCIAHKLHDDFADVLNTAAREDDCIELVNRSLRADAKHDRLPLGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY02</accession>
    <name>A0A6A6NY02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_54266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY02"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="10530" checksum="7E5CBF5503B3D3C9" modified="2020-06-17" version="1">MASWRTSYSLEAFTIMMLCSFVTASLPFPCYANMPGRRITVNATHLSVLCDKQVTQTTNLRGVSQAPAGCSAVWHHYSQLPNSNFHHRRSRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY46</accession>
    <name>A0A6A6NY46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY46"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025485239" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10632" checksum="C3F735C8B24A9DE1" modified="2020-06-17" version="1">MNTTRSSSFFSFLLLPVLDVLKQAEIPAVSCVPDPPFPQLPQYRLAMARLTAGRADGKPALTRTWLVIVARRLEHGTLGACENADRATRPRRSTGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYK1</accession>
    <name>A0A6A6NYK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_364561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYK1"/>
    <dbReference type="OrthoDB" id="5283654at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF6">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G00280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="8"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="314" mass="33839" checksum="487ED4BC219DE61A" modified="2020-06-17" version="1">MTTPQSVLVLGLGELGTAVLNALCSHPLLPTSSTTLTLLVRPSTLSAPNQAQKALLDAFRARGVILQPGDIVNSSTAELTALFAPHDVVIGCTGMAAPAGTQVKQARAALAAGAPRYVPWQFGVDYDAIGAASAQDLFTEQLEVRGLLRAQERTRWCVVSTGIFMSFAFWEGFGVVGEKGEVVRALGSWENGLTVTAVEDIGRMVAEVVFAEGAWPVEERGSGIVFIAGDTLKYKEFAEVVGRVTGKEVRKELWTVEKLEQDVTEEPDNGMRKYRAVFAKGVGVAWDKGKTLNARLGIELQTAEQWARESWNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYL0</accession>
    <name>A0A6A6NYL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_422200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYL0"/>
    <dbReference type="OrthoDB" id="5372703at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="17921" checksum="CAA757EAB6AF3BB6" modified="2020-06-17" version="1">MANTNVFVDHYPEAPAEIEEPLVHPLNRLEPDNVMHGDRGSNQQHRPPTISSLLFPRFFNRPPTSPQTQPIASFHNPIFNVPSTAPSDVSSENPNSLETPKPDITLGLAHASFGSFRRAVLMLLQDECHVLSDPHQMEIGLRFSFVFIESKGGALERMDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYW5</accession>
    <name>A0A6A6NYW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-splicing endonuclease subunit sen54 N-term-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_346065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN54 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYW5"/>
    <dbReference type="OrthoDB" id="408683at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024337">
        <property type="entry name" value="tRNA_splic_suSen54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024336">
        <property type="entry name" value="tRNA_splic_suSen54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12928">
        <property type="entry name" value="tRNA_int_end_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen54 N-terminal" evidence="4">
        <location>
            <begin position="72"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="458" mass="49897" checksum="3F94F7C144D0E71F" modified="2020-06-17" version="1">MADADEDAIIPAANASDINLDDETQDFRFLSSLTSSLDPTQATLPRRGEKDFEPHLTQVQSNALSASRSAMHAAISAPRVHSHKTYVRATFDAETGGAWVEKIRGPHFRTVGRTRSGKVWLLPEEALFLLDRGSLDIRWPQDNSGDNPTHASGGKSESLSDLSASDDETVPLGEYKIGDEESSISDPQDNGTIPMSLQAAYAVFTQPERVPPGSALTLEKYTVYASLKRAGYIVLRAPCWEAPGGPKFETPLGGCSAPQPSQSASLFSSTWQLLLATVERSTRPAGEALAAGPLVAPGLYRSYHDIYRRLIVVPSHDPSQANSASPRKAETNCEERLSVTYYVYKPQPTFRKSAPGPPDFYVSVLSARSQNVPELSAVVSLLDQTPQTIPPQPQAQMYQRLKQGYRNVILAVVDQGVVSYMRVADAGFSTIRLWDRKPSRGNKGAGRGVRRGILKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYZ2</accession>
    <name>A0A6A6NYZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-rRNA-processing protein PNO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pre-rRNA-processing protein pno1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_41039</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYZ2"/>
    <dbReference type="OrthoDB" id="1932641at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000009">
        <property type="entry name" value="RNA-binding protein PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="9">
        <location>
            <begin position="108"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22685" checksum="0E6456D8894F6412" modified="2020-06-17" version="1">MQIDLEGRPRFPPAADTAITALRVETRKVPIPPHRMSPLKQHWPKIYPPLVEHLKLQVRMNVKARAVELRNSKATTDPGALQKGEDFVRAFSLGFDVDDAIALLRLDDLYIETFEIKDVKTLQGDHLGRAIGRIAGKDGKTKFAIENASRTRVVLADQKIHILGGFKNIHIAREAIVSLILGAPPGKVYGNLRTVASRMKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZY1</accession>
    <name>A0A6A6NZY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_345461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZY1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="19842" checksum="321738BA5EE2702D" modified="2020-06-17" version="1">MASASGLPLGPSLLSFSARLVRPAIGFCAAAADHRTTKYPPFTPPSLLLLSLLAHAARSLHLARCAPANHRKAKAAPISAPSGALATTAGDQTSCGAGCVRLEIVNLSFASASAPRTVPRALGATARRALPWPCFESVLGRGRLPPGRADEWDGHLPLDAEAVSCCREAAWCGRRGKLMEREAGGRAEGTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I1</accession>
    <name>A0A6A6P0I1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_37899</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14012">
        <property type="entry name" value="PK_eIF2AK_GCN2_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000379">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2-alpha kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000821">
        <property type="entry name" value="Serine/threonine-protein kinase gcn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000074">
        <property type="entry name" value="Serine/threonine-protein kinase gcn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016255">
        <property type="entry name" value="Gcn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000660">
        <property type="entry name" value="Ser/Thr_PK_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="151"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="482"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="553"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="601"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="709"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="488"/>
            <end position="496"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="511"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1523" mass="170754" checksum="683041D951CD12A1" modified="2020-06-17" version="1">MQGVRERSRHEIETIISMKPKELLGEVMIYEIASSIQEVLEDAVASREQDNALPSLAEAREKEVEKAHELARRQEEDLQKKMEEEKAEEDRALKRMVDDEMRRRQKHKSRQSTSVIGNSLSDPAKLNMDAILFDRLITCQEDNNTFQFSAVAITRKVGAGPLTEVFMSQPMTSGDQTPPCLALKKTKVKVTSSTQTKAKKRILELEEEIEDLKRLRSDSIAAVLDFKIEKLESESNESKLETWEISILTDFGNKGSLCEMLELIDTIPTDRVRSWSIDLLEALDFYHRNGVIHKRLHPNNVLLSRSSSSGAISVQLADAGFQESLYELRDIVRSTKPAVLTSAYWIPTELSQAATISRRSRKTDIWDLGVIFLQMIFGLRTPEQYSSPSALIEALELSQPLEDIIRKFFRPDTKKRPSAFDLMPSEFLRSEAPVFDQQASRPPLPSRLSSSSASLPIPLDRRVRRESSGAGAGMYSRYASEWVETGRLGKGGYGEVVKARNKLDGRIYAIKKIRLNSSSALSEVLSEVMLLSRLNHPYVVRYYAAWPEDDTTSISETEEDTPSFSEDTSSVSKKPGLNVDFGQSTGGLDFISSSGFPKIEFEDDSDENAVESDSEADDDIVFQQDNGGQPESTDSSPALQKKRSQTSSRAANPPMKVTLYIQMEYCERQTLRDLIRKGLYSNPDDAWRLFRQILEGLVHMHSHGIIHRDLKPDNIFIDMANNPRIGDFGLATSGQYHLADKAVSGAHPDGDMTRSIGTTLYVAPELRSDVGGSYNDKVDMYSLGIIFFEMCYPLKTAMERDHVIRNLREKIHTLPQEFNSPDKALQGSIITSLISHRPSERPSSAELLRSGKLPLQIEDETIRQALQGLSDSSSPYYQKIMSALFSQSSNREVKDLSWDLGAANGAHSAQLSDLVLQGLVKDRLSSIFRRHGAVEIQRDVIFPSSSFYSNNSVMQLLDASGTLVQLPYDLTLPFARAIAREAPAAEKTFTIGTVFRDTYTGGAPRSNGEADFDIISYGTLDLALKEAEVIKVVDEIIDGFPSLSSSQMCFHLNHSDLLDIIMDFCRISKPQRPTVKETLSKLNIQQWTWQKIRNELRSPTLGISSTSLDDMARFDFRDTPEKAFGRISSLLEGTEYLDKTHATFAHLRSVMAYTKQFNVRRKLYVSPLSSFNEKFYSGGILFQCLFDTKRRDVLAAGGRYDRLIADHQPKVQGHFTGCHAVGVNLGWDRLVTSMARYSKPSGKSSFLKKATEEELQGHWAGRRCDVLVASFDKTVLRSSGVKILAELWAHDLSAELAVDARSPEQLLANYRDDKHCWIIIIKHEASGTGKPDLKIKNMLRKEDTDLRSSDLISYLRAEIRERDHREGVQARSLQRLMFGVGHGGVAEGGSSGGGEHKNSVQVLVAQHRSKKSNKWSVVESAQARARALLESYAACPIAAVETRDDLMDGIKATRLSDPDSWRKVVQSAPLADRAYLQQLHDLLLRYAAKWKEEENMSAVEEGGGMAFVYNFRSGSCFLYDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0L1</accession>
    <name>A0A6A6P0L1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pep3/Vps18/deep orange family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_286728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0L1"/>
    <dbReference type="OrthoDB" id="1845386at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="9">
        <location>
            <begin position="24"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="625"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="10">
        <location>
            <begin position="863"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="818"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="970" mass="109014" checksum="5A1D2DB0D1B4980C" modified="2020-06-17" version="1">MAFDSGGGYVAASSLQDLAETSLPIFNIERVQLQFSLSSDFVAAQVANNVLVLALSTGRILRIDLDSPADIDDIDLPKKSTEIGVIRRMFLDPSASHLIITTALHDNYYLHTQSRHPKALSRLKGVPIESISWNPSHPTASTREILIGAADGNIYETYIEPSTEFYRREEKYLKVVHRVHPSDGPVAGLWADLVPGRPDARRVLVATPAKLFHFAGKVGRYGSDGSSVYSKLFESEAPTVQEISRAQLAPSMLAVNPDPSDGQFAERSDSERVFAWLSSQGVLHGKLLASTDLSGLGNKTFSELKLLPRTALPASQSAMRSARGGQDPVKSMVLTQWHILQLVEGRIIATNRLDETVVLNQSILEEGQNAIGLVADLTKNTFWLFTEQEIFEIVVNDESRDVWKIMLKQQQFEAASRYAKTSFQKDAVATASGDYLVGKGQFQEAALVYGRSTKPFEQVALTFIDNDEQDALRKYLLTKLQHLKKTSTMQRMMVAAWLIEIYMSKLNTLDDTITTKAEISEGMNAKDSQGQLQVVRKEFQDFATKYKSDLDKKTTYEVISSHGREEELLFFATLVNDYNYVLAYWIQRERWLEALNILKKQTDAEVYYKYSTVLMANVPVELVEIMMRQTNLSTQKLIPAFLNYNKITRVPLNQNQAVRYLLFDINQRQSTSAAVHNTLISIYASHPSRDESALLTYLEAQSYAHEQNYDADFALRLCIQHARVQSCVHIYSAMQQFAQAVDLALKHDEVELAAVVADRPADEDPALRKKLWLKVARKVIGQSQGIKAAISFLKRCELLRIEDLIPFFPDFVVIDDFKEEICAALEEYSRAIDGLKAEMDDAADTAKHIKSDIRELEHRYAIVEPGERCYVCRLPLLVRQFFVFPCQHAFHADCLGKKVIEQAGVAKSKRIKELQVEVGRGTSTGAKRERAVKELDALIASACVLCSDSAVKQIDEPFVLQSDNREEWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P123</accession>
    <name>A0A6A6P123_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_363856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P123"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="180" mass="20838" checksum="15732069306BC8C2" modified="2020-06-17" version="1">MSANTKITLIDLTPKHSAALKRAITYRIDYERNLAPNTRKQSTLSRRIARCSILGTPISMEMCPAISHIPSLKSRQCSEPCCKDIYVYPNGRNQIFKLSELQIQSCGRVPLPESIQDQDAPEGFRFRAEIYALRVDPYEFMSLSNFRNRYERNVSEMRSVRGMRRVENDPEFMEAFKAFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P239</accession>
    <name>A0A6A6P239_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SEN1 N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_363047</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001152">
        <property type="entry name" value="tRNA-splicing endonuclease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024481">
        <property type="entry name" value="Helicase_Sen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056474">
        <property type="entry name" value="SEN1_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23576">
        <property type="entry name" value="SEN1_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12726">
        <property type="entry name" value="SEN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase Sen1 N-terminal" evidence="10">
        <location>
            <begin position="88"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase SEN1 beta-barrel" evidence="13">
        <location>
            <begin position="1156"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="11">
        <location>
            <begin position="1304"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="12">
        <location>
            <begin position="1600"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="857"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1838"/>
            <end position="2014"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1478"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="866"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="897"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="965"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1838"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1862"/>
            <end position="1899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1900"/>
            <end position="1912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1933"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1964"/>
            <end position="1984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2014" mass="223943" checksum="EDE42B7FD0B135D6" modified="2020-06-17" version="1">MELPQKLEKLRSLETDLHLFCPRQGSEDQSCYFVEDIADGNLKDENSAQRAQREAKIHEADERCELVLDCMAILAFHADDASEYQHWLKKRIEDQMQSCDVCVRVYHRSREVLRNRLVADFDEEDVATFMETVDRFNYERIVRGLDSATKTLTNLPEKSRTLRSLKSDEIFAFFEALSCEPFLRDEATVKAHFDAPFELVQTRKPLKIRNYPPAVEYFIFSTNELRNTWALQHLQSVDRDILSAEFENGMRWPLSHAMKRVQMENLDTSFLPRFWVGLRLIVDKLSADLITHSLRGMDVDPYKLTLEHLHLDFQGFENLVATLQQLVEKTPRQYWDSMGAISPTVIIQQFCHSPSLGRALMSMTEDETSPEFTRVKDLFAWTRPFLHSIAPSNLSPACRILAGQLLGALQSPKFPQVARSFCKILGLEHIDNTLRRLSARSDVDSWVGAATVAEVIDVVKEHVGSIIADIKLVHTEKKHNQAASQLALAVMRHAFGLDYVALSIHNTLLKNKKQVEQPTDALSSSLWDITTSTISAGNVALGLNTLSGWQQVVSVEKFESTGGLPLTTAMRRFNDTLDKVSGFITQVIESLADIPPATIEATLAERANATLIVVPLFSYNSDTRQSVIELFKSVSSQGGRHEAIAHLLTSKYVSILGAVLQTVKLAWHKKTFAPMPSSIKLLKDIVDIMCNSQDGILRSRKLTDEEGKTSEEFWQMQWRLLAVIFDKTEEWSNSQHKEDMMEFCRDTMEFADYLFDQHAVFASALADVAAEGADKKEIGRRLIHFPKSCITSAVRWLRLRDEYLCAKSVSLITGLLTRLRDAHLDIPTPALHFVCDIISGTTKSKLSGQQKAGLQRALGIDEPDFVDGKNDKSPSVEQDAKPAKQTSMADWVKQGTLAPTTKPAQSQASKRLSDAVEGPKPASGRPAPSEVSKPARGRESSKTPALLPGTTRPPPPKLDALSFKQRRDAEKEAKKKRDALAVAQAKKNIPGASQTSNAGPALAGLGVAGKDHSAKRSRMMVSDNDTSEEDDDEALDRELFGIQASKRQRTASGYQNVRAEAQRNLLAPQVPVKKQRQARSAKDMRARLAPDLSGLHRQILGWDYFHQGDFPPNSRPEMYSRVPNSFHNPVEYQQTFGPLLFLEAWQGFVKAREENNLKAFDIKVISRSSVDAFFEVGTTMTHEDNKEVMISDGDIVLFSESEKPTMTKEAPHCLARVARVTRKKSHMEVLYKVLPATPLLRALHPNMVVFGAKVQSITPLEREYGALQALQYYDLCAEIVRAKPSPLLQYSDRQLSPIMGAYSLNKAQAKAVKSALDNDAFTLIQGPPGSGKTKTIVALVGALLTDLLNREKAVMIQRPRFPGGRSSPPSPPPPKKLLVCAPSNAAVDELVMRFKEGIKTTTGLHRKINVVRIGRSDAINANIRDVMLDELVNKELERTTGGAHDAREKTQKLMKEHQAVSEALRDARDRMDLAEGGNREIGEEIGELKRRKAALSTQIDNARDAETTACRDADISRKRAQQKILDETHVLCATLSGSGHDMFQNLNVDFETVVVDEAAQCVEMSALIPLKYGCAKCILVGDPKQLPPTVFSKEAAKFQYEQSLFVRMQGNHPNDVHLLDTQYRMHPDISTFPSQTFYDGRLLDGPRMAKNRKRIWHCNPLLGPYRFFDVKGQHQSTSKGHSLINVAEVHVALQLYDRLIQDFGAHENFSGKIGIITPYKSQLRELKNRFSARYGREIFDIVEFNTTDAFQGRESEIIIFSCVRASPAGGIGFLQDIRRMNVGLTRAKSSLLVLGNSQSLVRGDYWRKLVENSKTRNCYTSGNLMNLLSQKSVIPDELLPRSDEDVEMRSRTNSTATPPGDKSAASSGKSSARNSSPKKSPGLGASSSSGPGAKNSSPPTSGLSKESPTSGPSRKRSTSEMLAASDEDVVMKDGSSPAGSAPGSEPDPKRRKSIDSSKAASSAETSPKMESSPSDEAQSPQDTAQPPKRPLKKRKKSSCFIDNSIANKARLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P266</accession>
    <name>A0A6A6P266_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein sip5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P266"/>
    <dbReference type="OrthoDB" id="21471at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24139">
        <property type="entry name" value="SIP5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039301">
        <property type="entry name" value="Sip5/DA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315:SF1">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="658"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="778"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="841" mass="89314" checksum="5B833673AA7ECE26" modified="2020-06-17" version="1">MGNSSTKEARPPSSHPQSGPGSASSPTAAGPSTSSPHGQGDRLASSSLYGARAHRGSRHDIFAAIGGGGPSDRDSPALEVRRETKAEREARKLEKERVARAKERERSMREEGVDGGYLVTLGTYTGPEDFNKAIVRQLMIERRLAPFWRGLNDHKDSWVEHQLVAAARGLLIPPADEAPSDVPSRTVSKTNENAKSSDNNISHLTVPMSGRSQSYNSDRSTSYLSPSHPASSLPSPTSPLASPSSPSPLFRGRAKTLAALTTSSKDSSHADMTPQEVQLPKDPYYNGQAIEAFLYKDATECPICFLYYPPYLNKTRCCDQPICSECFVQIKRPDPHPPEHADPSNPNAGADSQSPQQSDDSQLVSEPAACPFCVQPEFGVTYEPPPFRRGLAYAHQGHPQPLASATSAMSSTSSLASAGFGSPTGISSSRRRTTSLSANAPAVITTDRIRPDWAKKLADARAHALRRSAAATALHNAAYVLGNQGPSDGRSFGLGRRRRLFGGDSPGSSGRGTPRLGEGVSLARRLSSRRSRMEDLEELMMMEAIRLSLAAEEERKRKEEKEAAKEQKKKEKREAKETRKREKKEKKNGGGGIGNLVQVEGKGKGVDRTGGAGCRGGSAGFNPLSEPTSTINTSAEPLAATAAAAEDPQRHLENSRAQIQTQNQSQQPNQFADGVVSSMPNPDSTSSHRTFLRRHLSNASSSASSLADGGSSSFGPSPNTSGLDLAPSASGDGISSETLPEPMLNFQSLAAMIGDEEKRREDADQRASGDSSADGGKESSNVEDASAALQETSEDLANSHATVKPSNGLVRQVSGADADMTNASPSIKGPEKPFVSGPSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P282</accession>
    <name>A0A6A6P282_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNAse P Rpr2/Rpp21/SNM1 subunit domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_271771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P282"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17115" checksum="E77A451BA3357122" modified="2020-06-17" version="1" fragment="single">KSAKSKSIPNRHLHARISYLYQAASYFASQHIYGIASATQNEKQVNDKVSKHHSPKESLDTKKGNAHALPTHFNAHLLAVSRKSQSHLSPALKRSICRRCHAHLVPGATSSHRVANASRGGRKPWADVLVVRCALCGAEKRFPVGQERQAGKKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P287</accession>
    <name>A0A6A6P287_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Set1 complex component swd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_302112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P287"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037850">
        <property type="entry name" value="RBBP5/Swd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040:SF1">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="475"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="477"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="519" mass="56646" checksum="E09DB4822439EBDC" modified="2020-06-17" version="1">MNLSLLDPFVLAQDLPEALVGRLRSGHSTSIQFSHRGDYLASGRLDGVVIIFDIETNGVARKLRGHTHQVQSLSWSANDRCLLSAAHDWKCILWDLKDGSRLRTVKFEAAVFIAELHPKNHFIFAAALFEEQPMLVDMTGDVPIKRTLPTVPRRTEAERETISEKQAAQDAKQTTTVIAFAPSGDHIYTGTNRGWVNIIATATRQTLYSTRVTNNILVLIRVAPSGRSAVINSTDRIIRTLHLPDLSGDSGNVDFDNPRLVEVEHKFQDLVNRLSWNHAAFSSGSSGEYVAASTFMNHDIYVWERAHGSLVKILEGPREELSHLEWHPCRPFVAAVGVDSGRVYLWSILTPQRWSALAPDFVEVDENVEYVEREDEFDIQPLEELHKRRLDLEDEHVDVLTVVEPAADHANGKAAGAGDASSARAAAAQFQMPILLDIEQSDSEDEVIAVGAGQFRRKSPGQGREWMAEVGDVVAGSGAGMGANGSGTGTPLAGASGDEAGGGGSVGGGRRNGGKRRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P328</accession>
    <name>A0A6A6P328_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_390674</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P328"/>
    <dbReference type="OrthoDB" id="5361565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF27">
        <property type="entry name" value="CHITIN-BINDING TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025515754" evidence="7">
        <location>
            <begin position="22"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="8">
        <location>
            <begin position="47"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="483"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="541" mass="57621" checksum="57D20DEDAA933453" modified="2020-06-17" version="1">MASCSFLVLCPLLCLFGAVSAQNGNCSIPPVTVPIKNVLLSNGQLRRGIAMDMGSPPQPFALLPAWFANNTYIYDYSAGSCDDLTEDGCVTLRGGLYDSSSSTTFIRFDDPAAAGADPVDNETVTDSNWGRDSLVLNSNSTLDDYPFGIIDEDFSAGYTRQGLLGLSSNSSILNALEAAGQIASRSFSFFWGLDGATEPVRTDGGIVFGGYDAAKIDGDQNITAQFGGYDSCSSGMLITIMDVELNFPNGSSPSLSPDRPFVCCVLPELPFVVTLSQSPYFDNFESLTQTSNIGRSSGEDFFNMMYPPDEVYTGDLTFKLENDIDIRVPNHQLVKPEMQVTDQGSVFENTTISVLLINSLRDANEDDVLAVGKYFFTSAYLTVNLDTQSFSIFKANPTFDTDPVAINDDSSAADCEVTGTISAGPSSSPTPQQTIAGDGSNSPSSLSGSAIAGAVVGSVFGAALIAVAVLYFLQRRRWRKQAAGGPKDDAVSLSTTSVEPGFNPGLQELGGSDPPEVYGSDPPKHELPVPYRDRVRVAELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P376</accession>
    <name>A0A6A6P376_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_410360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P376"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="184"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="344" mass="37927" checksum="5C7034D1E29A0A2F" modified="2020-06-17" version="1">MMDGNETKSNTVPVVDFGPFLDGKGEDKQRVAKEIDNAFKTVGFVCLVNYGIKQEEVDKCFEWSRRFFDLPMESKMLAPHPPTAAHHRGYSGVGLEKASHSDFDEKPHEELRQTPDVKESYEIGNEEDEMQPNIWIPEEVLPGFRDFMNAFFGSCTSLTGSILHSLALALSLEPTRLSAAQSRALYQLRLLHYPSVPASLLRSGAATRIGAHADFGTLTLLFQDGVGGLEIERREGPDGARTGEFVGVPAVPGGVLVNVGDLMERWSNGRWKSTVHRVGLPPTAGGEGGDEVVRDRYSIPFFSTADPETVIECLPGCSSEEDPPKYEPVTAWGYINMRMQALYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3G5</accession>
    <name>A0A6A6P3G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_21451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3G5"/>
    <dbReference type="OrthoDB" id="5345571at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057082">
        <property type="entry name" value="PH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057081">
        <property type="entry name" value="PH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23076">
        <property type="entry name" value="PH_FT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23074">
        <property type="entry name" value="PH_FT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="282"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="410"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="59878" checksum="32822C7C7527E8E7" modified="2020-06-17" version="1">MELPERMLVEEVKDAEDVAAGLQVFLEQVPPRATDISANMSELFAISSTLRAFHHSFSPMELGQPSVMVAQNIAMTLNSLAYTLKSVRDMFGRSKYTAYSGSPQYRALWDDLDSQLRAESNQSLCSRLENYRIFLQGLFDLWMGTPSAIDLRIFHSEISSLLRRQELADDYAHQGGAMARPPLTHFATYPSYAGRSSATSSSNDYEPYSGYPYSPEIPMNTPQSPTFSNVSSQTYSSWETYSSSSSGTPLHWVRKVFDGRHPLTPFRRAGQSTRCVGRDDPQIIDLLERDAFIRVHEMHFEECDVRVRFYWRPSDHRARIAYLSHDRNTGLATRFCLPFTALQIRRADSTLQLCRADQGDGRLILWANLKFTAYERMVLFYCAFVAMKHQDHRSSSSSFQDICEPPDNVQFAGEVMDDSFLHIFRVYRDRDSGAVRFETTPRRGKMKGTPIWTAFVTDKVGDRHWMKRIDSKTIQFRGLRPYVFCDNYVPPRTPSGHFQLKFTSKSDSEQFSHVMSGLARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3P2</accession>
    <name>A0A6A6P3P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_420989</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3P2"/>
    <dbReference type="OrthoDB" id="5377623at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF7">
        <property type="entry name" value="TRP-LIKE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025619250" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="36"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="649"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="680"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="58"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="742"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="818"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="940"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="742"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="867"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="885"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="963"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1034" mass="112486" checksum="C6E1026A45ED67D7" modified="2020-06-17" version="1">MPSTRWPRTATPPSIWTRGVVAGLALLSLVRTCVADTRWFTWQGDDGETVWLQDNRKPALYTDDFGDCLGESSVNVTRFDAAYYKDNMTVVFHLAGETALVSEALMMYIGVYAYGENRFDLTFNPCYANIDSLCPMRENVSIEANGVIPIGPEDVQGIPNIAYSIPDFEGEAILRIFANSTQTEIGCFSAVVTNGNTFRQPEAVGSILGIFTAVAVVTSFATAMYGETVTVMRKHYAHSLSVFVVFAVLQHIYFTGALSMNWPSVLVAFWSNYAWASGMIYSEGMQNSINDFIGANKGNTSAVGAAGVGEANPNLGGGYDISQIYKRRPLKLHMLKRKLAPRDAVNGLEGMQMMKRDLANSSDGFTYYGQPVKPGLPLPGNYSGFAGTLGQEKIPASNAFLTGFLWLLILLLLIVACVILAKWVLEGLIKLKAVRQDRLTYFRSHWLRYTSATALRILFIAFFMMMFLTLFQFTYDGGQGVIAIAAIVFLIFFLGMFGVAGYALYYRLRIGRWVSKPDRLNLERRKVLKVVPWFAFHRESAATEADLQRVYAGSVPFWRIEHLPAETEKSVHEDEDYTSKFGWLASRFRRSRWWFFGAWLVYEFVRACFYAGASGHPMTQVFGLLVVEFIAFVAIVAARPFEGQRLNALVVYALGFSKVATVALSAAFDIRFNLARIPTTAIGVVIIVIQGILTILLLVAIAVGAVTSYWSLARNRDAIRPRKWNPWRERFFAHVDRAAADPPRAQREAFRAEERERRRRERANKNGGGSSIGTGDEKGILASARPRPEGPYFSVNSVRRVAKIEDEDEEFMAEISGLDLPSSHGGTAGAAAADPYGSRTASRTSFPRFQPLSAGGSADDIAAPPAVASPPPPPPPPPGPPSRPPSSSAAAALAGPRAARANSLRSTASLRSSSGNLPFGARVHRASWSSRDFADYADGAAAPAADWGSRRRTGTWSAATEGAGAGAGGAGPGVYLQQLGASRSGESVGRVPSPLAGSGMPERGFASREAGRTSSLKGRQFGQDGEARGGGFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3T1</accession>
    <name>A0A6A6P3T1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative SNF2 family helicase/ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_205467</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3T1"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031010">
        <property type="term" value="C:ISWI-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000036">
        <property type="entry name" value="Chromatin remodelling complex ATPase chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000022">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000234">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.30:FF:000003">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="204"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="500"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="866"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="134"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="824"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1044"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="832"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1082"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1092"/>
            <end position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1121" mass="127974" checksum="5D06A68968EE9E4D" modified="2020-06-17" version="1">MAPSRSRNSTSGANSTADVSAADVDGTNDYDEPMGDYQDTPDYTKDSDTNPNTTASSVVGDALPTDGRRRRAEAFQLRKSVFGKKHDRLGESKDDDSIRRFRYLLGLTDLFRHFIDSNPNPRIKEIMAEIDRQNAEEAKSKKGHARKGGAGGERRRRTEQEEDAELLKDEKRGGQSETVFRESPAFIKGGEMRDYQIAGLNWLISLHENGISGILADEMGLGKTLQTISFLGYLRFLCGISGPHLVVVPKSTLDNWKREFSKWIPEINILVLQGAKEERHQLINERLIDEKFDVCVTSYEMILREKAHLKKFAWEYIIIDEAHRIKNEESSLAQIIRLFNSRNRLLITGTPLQNNLHELWALLNFLLPDVFGDSEAFDQWFSSQEEDQDTVVKQLHKVLRPFLLRRVKSDVEKSLLPKKETNLYIGMSEMQVKWYQKILEKDIDAVNGAGGKKESKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHLVNNAAKMVMLDKLLTRLQAAGSRVLIFSQMSRMLDILEDYSVMRGFQYCRIDGSTAHEDRIAAIDEYNAEGSEKFLFLLTTRAGGLGINLTSADIVVLFDSDWNPQADLQAMDRAHRIGQTKQVRVFRFVTENAIEEKVLERAAQKLRLDQLVIQQGRAQQQAQKAASKDELLSMIQHGAERVFQSSGGVNTGGVQANISEDDIDAILKRGEERTAELNAKYEKLGIDDLQKFTSDSAYEWNGQNFVDRKKDIGIAWINPSKRERKEQSYSMDKYYRNALMTGGRTAETRPRIPRAPKQQAMHDYQFFRPRLGELQDKETAWYRKQNNIKAPLMDGSESDLEQRQAEQELDQKEIDNAEPLTEAEKEEKEKLAQEGFGDWNRRDFQQFINGSAKYGRKNYDGIAEEVDGKNAEEIKEYAEVFWKRYKEISNWEKHLGVIEEGEARIKKMEHQRKMLKKKLAMYRAPLYQMKLNYTVSTTNKKVYTEEEDRFLLIMLDRFGVDTEGIHERIRDEIRESPLFRFDWFFLSRTPVEIGRRCATLLTTVAREFDSADGKITNGAGRGKHKAEEEEDGDDEDGPVKKKTKKGVKNKQLDTVKDGSKATSASTSRAGSVVSNSSAKGKGAGRGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3U4</accession>
    <name>A0A6A6P3U4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase/oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_342487</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3U4"/>
    <dbReference type="OrthoDB" id="10251155at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052904">
        <property type="entry name" value="Acyl-CoA_dehydrogenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041504">
        <property type="entry name" value="AidB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707:SF2">
        <property type="entry name" value="ACD11 DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18158">
        <property type="entry name" value="AidB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adaptive response protein AidB N-terminal" evidence="6">
        <location>
            <begin position="26"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="5">
        <location>
            <begin position="356"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="5">
        <location>
            <begin position="474"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="670" mass="72537" checksum="5EC4D760CB850D1D" modified="2020-06-17" version="1">MATGPAKHTAQPSSGTDGFFQAPPQVRNQFEEDATLRRVFEHFLSTSDRARFSGPLASFADLVLTPKVLAWVVDAETNPPFVRELDTWGRRTNELVTSEGWRQLQALGIREGIVATGHERDRFGAAARVWQFLKYHVWSASSANVTCPSAMTDGAATLLTRHLRRKPGALEASGGFADAMSSDMRGVLEKAYARLVSRDPERAWTSGQWMTERTGGSDVRGTQTLATLDPGFVAAAGEAALSVREDAEGSPLGPWRVDGFKWFSSATDADMTVLLARTPPPDGQSEAPISAFVAPMRRRLGPTEASAVGVPLTAPQGTVLNGVRIQRLKSKLGTRPVPTAELELRGMRAYLLGAPGQGVKEISTVLNITRLHNSASACGYLGRGLSIARAFARVRRSSGRLLADTPAHVKTLAKVHVEYRAQMMLTYLVAMLLGRVEYAGDDAPRPGSPPSNNSSPTLPYLNSLTTSQSANLLRALTPVMKALTARIGIYGLQECTEALGGVGYLESPDPNANIVRLLRDACVLSIWEGTTDVMGDDFARAVKGRGAVEVVGALDAFVHRALGMWSGAWKDAARAVGMRWERVKADIGAGEREELAARGREMLDEAGWVTMAILLVEDARRDGDAMSAEVARRWVAKKESVMASRPWNEEAFWDKRIVFGDGEGKESARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3U5</accession>
    <name>A0A6A6P3U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_283518</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3U5"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF95">
        <property type="entry name" value="NUCLEOLAR PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="100"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="223"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="340"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="42873" checksum="2CB722A132B3F46E" modified="2020-06-17" version="1">MDAEGAAKKRKRADAADVAIPDEIEIDVSLPEPLSKKAQRKATKRRKSDARPLDGDTVARKHSDGEARTSEDSDDDDDDDDDAHSPDKQSPADSKRRSPFGIWIGNLSFTLTKAALRSFIVDNAGIAAEAVTRIHLPAARDAVSKKPRNKGFAYVDLATQPDQIAALGVNESLLEGRRVLVKDAASFEGRPAKDALASAAAGGGPGKVDGIHKALPNGKTPGKKVFVGNLAFDVAREDLERQFEKCGAIEDVHVATFEDSGKCKGFAWVTFEDVEAAAAAARGWTLLEQEDSEDEQDDDQDEEEAKRNGKPRKWFVNRLFGRDLRCEFAEDASTRYEKRFGKGRKKEQGRGWRDSEDVDGATMKRKNTSVAHAHAPRESTAIVQGTGSKIVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P471</accession>
    <name>A0A6A6P471_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_212732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P471"/>
    <dbReference type="OrthoDB" id="5342004at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="54940" checksum="223FE8159173D558" modified="2020-06-17" version="1">MAVFIQYQPPRTGSPVFKGNTSRPSISSAPAPFISHGLAAFAPGGQDGQCPNWGGRDDNTAFVDRIGSDHQKGNIQERQVVDDADTETLATSTKRDSGWNGIRRIGDTGGNRDSDSDSDGDSSGCSVEFLAAGEAFSKEKRKGAMAGSALGFRPASPDRLVDGSGPKGGLAASGGAVGLSSGADMIISVSPDPSQGKPIIPGNDGSDGELCAGQEAPASAGNIYNVFAEYEKTFCMKKRPRQQLRRPREQRSPPSPDDPILLNGPAGASVGGGDLEIGPDDNVTTIGNPAGVASNDPYSRRLASAVPDDEPGGSKGPQRPAETLSALERPSTVSGSFAQESSAYQDTPSRKPKDNIAPNVAPNVAPNVASSGVGLLRRSSRTRKRPRPPAEPIFPSTDAPALKRPRRAIRETWKVREAREVEALALSGSCRKRQAARAHWPCYKVDRGVAVIEDIEEVYLADDQSIQCVVRWKSSLVVKENLVGKELHQRCEELFKAKYGAREWGKRFRKLTAKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P498</accession>
    <name>A0A6A6P498_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_411720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P498"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="439" mass="48496" checksum="695F92AD64D95B24" modified="2020-06-17" version="1">MDYVQATDSGLGSSPISGNGAKVNDHAPGSLSMLRGSDISQSGSSQAPEVVDQPQGLVINCTEHLVSDEAWGDFCDSLRENEEIIVEAGKNDSLVSWKLPGEFLQAVCKQFTPAETKKFSFPDEDPVIFSLFIDYVCSGNITFGKKFKLETSSYKSHQADYFTKEKYAGFSNSTIEKRDWQEPEKAWLLADKLNAEGWRRFAMKKVVNFYRDYYLPPDVVVFAYKNTSPGSALRCYCLEKVIYDSLNAENGGISRSNAKLEEFFEAGVEFLQDFFRIRSNGTAIDDPAKNMVRYISPDKEVPMLLKSTKPGKNPAKKPHVKPYLLKNAPAHAPNGPNCGTNCSHTDTSRGGTFGTPHGIGNSHLHQDGDWFTADDFRNIGRGESASQATHGPDRSQPCSPPVNDGARSSCQSSSYAHEFRNLSRSAPGIDAHVYPQWHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4M5</accession>
    <name>A0A6A6P4M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_282680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4M5"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052542">
        <property type="entry name" value="Cholesterol_Oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470">
        <property type="entry name" value="CHOLESTEROL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470:SF1">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="99"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1249"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1275" mass="139866" checksum="B1427501F9FE010D" modified="2020-06-17" version="1">MAPRVPPTKSTPTNVKQPATAGYPVPPLNAHKLPSKALKSATQAKKPKKAPDSTGKRFPRISRPVELLRATYDTVVIGSGYGGGVAASRMARGGQSVCVLELGKERWPGEYPSSLSDAAPEIHISGDFAPKDERSKPVDRGNKTGLYHFILGAGQNAFVGNGLGGTSLLNANIFLKADHKTMAQQDWPDELMEPGSLDEYYEKAAAMLEPSPYPRDFPELNKLKVLEKQAESMNLGEKFYRPPQTTKFQDGPNSTGVHMQASTLTGQDCTGVNDGSKITTLVTYLADAWNWGAEIFCECEVRYIKKHPKEGYLVFFAWHGAKRPEFEELFESDLMWVHAKKFVFVGAGTIGTTEIMLRSKQLGLPMSNRVGQDMSGNGDILAFGYNLNENVNSLGRDSPLPDHPIGPTITGVIDCRDQKDPLDGFVVEEGAVPSALAFGLQPLLELLPGEESEDDTIADRVRRHAAKLGSVAFGPYYQKGAVERTQIYLIMSHDSNQAVLTLKDNKPSLEFMGVGRTEHLQTLNKFMAELTHNLGGEFVNNPFYAALNQQQITVHPIGGMNLSSDGTADEGVTTHFGEVLTGDGTEFHDGLVVVDGALLPTALGVNPFATITALAERCVEGVAKKKGIEIDYTTRNGVLDMFGYPEHPIPKDQQLIEAEDMISKSLATGEGGIAFTEVMKGFIHVGDDIQDFKVAAEHAKGECADARFFLSVRAYDTDTFVSQSDHRAQLTGTFSNGMPGSPFMVLRGDFQLFNKDTKTPDTASMTYDFDMVGTNGDVIHFHGEKHINPSISFSPTRTWEATATLYVTLSWPDGSLVGKGVLEIGMRDFIDQMQTLTAYGRNDLVQLRSKLKFFSYFKDQVAKSFFSPLHVLQYPSPPVIGEEEKGKKAPNKTFKVLSKDGIESTMHMWEPTTTSTPGLTIVNILWVPGAAVDQQIFALPTIKKNAIEYFTAAGYRCWSVTHRTGRSPAAQDGWTSFDARLDIQAALVAIREATSEDKVYIIAHCAGSVALSIGLLDGTINPEWIIGITASNVFLHPEFARVNYLKARVPLITQAYSAFSNSSFFNSASTREDSLFQRALNQALRLYPVGYRDEICNSVVCHRCSLVFGKLWSHRNLNEATHSQLDRFTGGVSIKNLRHLMKMGVKGRVLDADAKDTLFTDANLERLRNIPIFFLSGVENTVYAPEATLTSYVMLRRLFGEKGYERVEFIGRGHLDCWMGAEEAGHGGVYELVRKKMERVIVMGKEGLRGPQGRIDKPEEDGAAGATATNGSISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P529</accession>
    <name>A0A6A6P529_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Stress response RCI peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_362427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P529"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF57">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="121"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21106" checksum="CAE3C4F7FAD80611" modified="2020-06-17" version="1">MCGTDCFLALLSILFPPIGVWVKRGLCSADSLINLALCCLGYLPGLLHAWYIIFAYPDDPFADDYNCTHGDHRRRGSSAASDPEGTRHVTYYYVQQPAPRRLSAQPSYGTMPPQNAEARSPRAAPVATAPPAGARADAVPDPYPGQAAGAANAFAGRVQTAGAGEQAQGQGQGQEGAGPSDGAPPPSYADAVKGDFKVQSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P569</accession>
    <name>A0A6A6P569_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aminonitrophenyl propanediol resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_202182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P569"/>
    <dbReference type="OrthoDB" id="204164at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF2">
        <property type="entry name" value="MANNAN POLYMERASE II COMPLEX ANP1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="411"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="411"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="54112" checksum="4259BE1E5195140A" modified="2020-06-17" version="1">MLPVYASSPQEKMHRHAFSNGHSAFPSLAGPGTFHIQPHKFQPRAQSARRRRRQLLIRLGLAVAGAFIFSLFIFPSLRAIFVPIFSLGIFSSTGLSAADSQIETVRYYDLNHVQGSARGWEREERILLCAPLRDAAPHLPMFFSHLRNLTYPHGLIDLGFLVGDSKDNTLELLTQLSEDLQADQDPNMHFGEVSIMEKDFGQKVNQDVESRHGFAAQAGRRKSMAQARNWLLSAALRPTHSWVYWRDVDVETAPFTILEDLMRHNKDIIVPNVWRPLPDWLGGEQPYDLNSWQESETALALAETLDEDAVIVEGYAEYATWRPHLAYLRDPYGDPDMEMEIDGVGGVSILAKARVFRAGVHFPAFSFEKHAETEGFGKMAKRMKFSVVGLPHYTIWHLYEPSVDDIRHMEEMEQERKAKEEEERRRQEMLARIRDQFDNPAQQWDEDKSRIRDMAKKGRNKEGGNSGGGGGPVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5D3</accession>
    <name>A0A6A6P5D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5D3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16653" checksum="63821E4848B109E3" modified="2020-06-17" version="1">MQVKGLGSLRELVGSMWDSSTHISHQGDEYFQGSSRAVQFDGSPSSDSRGVSQKEKRKKKKKKGKEAKCVPVSPTQPGSWDHEPTNEATAGARSFRRPLLTDIAYAPPSSRQLTVGLPLSDAAIPGSVRRLTSPAWGKLRHKWLSSRISALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5D8</accession>
    <name>A0A6A6P5D8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_378125</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5D8"/>
    <dbReference type="OrthoDB" id="5416384at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF8">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="368"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="646"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="702"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="746"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1014" mass="108870" checksum="692AB618ABB200DF" modified="2020-06-17" version="1">MDHPATSPSRSQTHARRDGSTRASDESSSSRIAHTLTACTRCRTVRKPLLAIDPSNNFPHASRSRPSPGLDAAVPSSVCRSLSPSRLIDSTIYLFFLIALCSLDALRKQRKTRCDPNLPRCGPCERTNSHCEYFDPARNRKIPRHYVVQLQHKVARLQKQIEEEEKEEVEPDPEESLRGAAAVRMNESDESKFLGPSSGIAMTRLVMQLAKEFTDSKSISEIVPDARQRRIKEQFAREEAKPTSKIYPLISNVAAATLPDKGITKMLVSLFYTKGQAMYPILHEPSFDQVVEDIYNGDDDPHKNFMVRMVIAISMQKMDTQFAGLADSFYLAALAYMEPAVQSMDLRTLQCFALIAGYSLLTPTRTAIYYIIGLAVRLLQSLGMHREDTITKGPDGQPLNALEVDMRRRLFWCILTMDFGLAHSLGRPSLFATGLATIDVQFYHACEDTYITPNGIVHSAPLSLRKWISIHFFQMRLLQLEIRRTLYQRKRPEPNDDQHPWFRQMQSKLDNWLNETPTGDADSGLNKMWPSPQVPRPSLQAAFRCFDACKFNVGMHLRQIKERTVDLTWIFTQSIFMAINTLLWTLSYSEIRQKHPRDEVYGYLRTALEAIQLASERWPGVTSALELYDNLIEACLKSYDKDGDIPISANSPSDASVASSSYVREGSRSRTTSPATVSSASLATPPDKPHLNMMPFGGAGSGHQQQQQPQPQQSSPGFASRSPAYSTTSPSSAAAAAAAYPTPTSQQAQHSPAHSHVQYSPPASQAVPVDQSSAAAAMSVPPHAPPSAQTAAGGAFNLDMPPPPRGVTFADGGAPGGAGPGAAFDPDSHFNRLPTNFPDIWNPAFSFGGGGGGCGGGSPGAGGGGGVPSSGGAAAAAAAAAAAAPPVQASPTPTSIAATLAAAAATTAAPRAFSPDGDAALAPPGFGAPPDYLYPTAWSMNGGAGGAGGYGGAVGGVGGGYAGGAGGFAGTDMGWGLNQAQQDELMQSLEADATKDLMRSMVDDSWAFWRGQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P669</accession>
    <name>A0A6A6P669_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_362120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P669"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025533387" evidence="2">
        <location>
            <begin position="19"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="133" mass="14489" checksum="07BD26A1819A7267" modified="2020-06-17" version="1">MAWNVLLLLEGACEKLAALPTILILGGEVDPPVPMLTTAPNKSLTPLSVMLFISSRQKTVGLLVAIPPSTYFLPWIVTGLKYAGAAEVARATSQILTSSRKSAMQIICDESPLPHEGKEEEEEEEKEKEEQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P681</accession>
    <name>A0A6A6P681_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_419916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P681"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="226" mass="25748" checksum="3B42A496BDC1A3B2" modified="2020-06-17" version="1">MPAENLILRFRLSTRGSQSSSRLNCAFPEIFGRRREISGVAAPRLGNSSLIAVLASKERRKSALYAMAGRQQFLSSAKLLSATLRPWQRVWRWVTGKFKPAFRGRCARGIAHLWPDFKRVPGKAHRRLVHRNHGQLDFRTKGVHSGLRHLTFVQNSKRPQKDKRQLHSTILQTGPPQTAYSRSALCKTFRSGPTILSRKKNVDQLKILPLSGTLKKTEMPRAQHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6B5</accession>
    <name>A0A6A6P6B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6B5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025587641" evidence="1">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="16831" checksum="55F6AAC5B8AD1431" modified="2020-06-17" version="1">MTELLALALAPASVFLLAPHATPLRPIRVTVVISRRTLCHLAVCAPSGNARKCRWRRRGLPSGKLAVAVLDCLVAAADPRVFAMAPDSGFSAVASVQISFVVGKVKGMAGVARSRLRRAARAHSNQSVLELLGEVVDIAMGATETPWVKPNIVTGMTASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6P2</accession>
    <name>A0A6A6P6P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6P2"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="488" mass="53455" checksum="5537B8A7A33DC15D" modified="2020-06-17" version="1">MSDHQRASEASKRILCSQEPTSATMRDPEGTSKPTDSDAIHHDIGLQGGEYDLAEHVRTCPLGAYCGVAFDGSSHTAAAASEMAPISLSNTGGHVGSSSAEFSVPSIKEEDDDNEPLWAANIPADVLKALASIDEPGDIPKTKKKPSGSDNKAVSTAINPDKNTPDPNLKSVLLANATSLGSEKPTEGRVHKKPGTTTYTYTSADNSPTGTRKLAVRRKMDSDMKDDPDEEDPPKSPVVKTEDFTSQTYHALVMESLIDHLSGIQSGTDDKDFGKEVKQDFELEEPEPYPRPAPAQSNAESTKKAGQSKTSGRKRKGGKSDHLLKDIQRKKDAQCKDDGTLLREQQALFGPGRAQATQNIGLACWKLGCSAKFQDENEIMAHAYEVHGQGYPCPAAGCGFLARHIKDIDKHMERVHPGTSLYRCHFCECLEQLYSKRRDHITSEHRWVKNACRAPTCRKGFPDEAEYRAHVEREHPEEASVRLQARRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6S8</accession>
    <name>A0A6A6P6S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_281395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6S8"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12163">
        <property type="entry name" value="2-Hacid_dh_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="128"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="228"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="366" mass="40342" checksum="8E424B0A46405D15" modified="2020-06-17" version="1">MGGGPEAKKDKVLFVLPFPEPTDVTDRLKRKFPNIDFEYINLTSHRDGVWVRHKELPKEIYHDITILGTLAVLPEKPEDCPRLELTHIFSAGINHITDNPVYKDTDVTFTTSNGIHGPQIAEWVVMTALIQSHKYNPLYELQKQHKWGQKHTSENYGKVSDLVGQRLGVLGYGSIGRQVARVGKAMGMDVIAYTAHAKDTPAARADNGYIVPGTGDPDGSIPSAWYSGTTKAELHRFLAQDVDLLLVSVPLTKATLRLLGAAEFAVLGRRNAFVTNISRGKVVDQPALVDALKDGTLRGAALDVVDPEPLPEDDPLWDAPNVTITPHISGLGDAYAKRAFEVMELNLERRANGEELINVVDKKRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7F1</accession>
    <name>A0A6A6P7F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_281777</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7F1"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="32914" checksum="BF715EFDE008B912" modified="2020-06-17" version="1">MAFGYTPRKIGAPNTLEHRIFIEKDGVPLSPFHDIPLYANDSQTVLNMIVEVPRWTNAKMEISKDETLNPIKQDTKKGKLRYVRNCFPHKGYLWNYGAFPQTWEDPNVVHPETKAKGDNDPLDVCEIGELVAKPGEIKQVKVLGVMALLDEEETDWKIIVIDVNDPLAPKLNDVEDVERHLPGLLRATNEWFRIYKIPDGKPENQFAFSGECKNKKYAMDIVRECAEAWERLITGKTQRGDICLANGTVQHSPDRINPSTLNIPPHHEQPPAPIDPSIDKWFFISGAPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7G4</accession>
    <name>A0A6A6P7G4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_195477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7G4"/>
    <dbReference type="OrthoDB" id="10629556at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025428560" evidence="2">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="17068" checksum="2A6EB6A3C3157FD3" modified="2020-06-17" version="1">MKPVSIAAILSILAFASAAPALHARGDTDPVESTANGGVAPYVNELADRGFPAVHMPGKRGDTDPVESTVGGGVKPYVNEAAGKKKAKRGDTDPVESTVGGGVKPYVNEAAGKRKAKRGDTDPVESTAGGGVKPYVNEAAGKRKRGDTDPVESTPGGGVKPYVNEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7H0</accession>
    <name>A0A6A6P7H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_369854</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7H0"/>
    <dbReference type="OrthoDB" id="295656at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="199"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="420" mass="45912" checksum="F29C52DA07A1AD2A" modified="2020-06-17" version="1">MTSPEVVAAIADVESSAAANKAAAYSQLLDKIFASSPGEEALAANLKAYVESILGDSLGIVSSRPLLANFVERFAELRDKPDVVIDVGEHALRLLEPKVVSYEEQDTRLKLAVAGAHEASDDFAASARTLQKISLDSSQRAVTADEKADVWIRIVRCYLEEDDPTSATGYLNRTKNILHDVTNPLSKLMFTLCQARIHDSRRSFLDASTTYHSVSQSRLIGEDEQLLALSAAMTCAVLAPAGPQRARALARLYKDDRAATVDEHPILEKIFLDRLLDPAEVDAFAAKLKPHQLAKTADGSTVLQKAVVEHNLLAVSKLYANIGFDGLGVLLNVDAARAESYAAQMIEQGRLAGHIDQIDRLIVFEGEGSGERKTAHGEGVFGRELMAWDRNVEALAEEVERVSTKIQNQYPEFYAEHMVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7M6</accession>
    <name>A0A6A6P7M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_408842</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7M6"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000001">
        <property type="entry name" value="Prefoldin subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="22405" checksum="0E31E094887825A4" modified="2020-06-17" version="1">MATAGSGSSKDAPTNPRGIPYAPFVDKVEDYVTSRTEVEGTLKNFQEMISKYQFMEMNTQRRAAGLRDKIPDIQKTLDTVRFLKTRKPDADPIETTFELNDTLYAKAEIPHTEEVYLWLGANVMLSYPLPEAETLLISKLETAQRSLANCEEDLDFLREQVTTMEVAVARVYNWDVAQRRKEKAEGGSEGAAASKGGGDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Q1</accession>
    <name>A0A6A6P7Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Required for respiratory growth protein 7, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_299093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Q1"/>
    <dbReference type="OrthoDB" id="20734at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018828">
        <property type="entry name" value="RRG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133:SF1">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10356">
        <property type="entry name" value="RRG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26209" checksum="8C8BAB7FD838064C" modified="2020-06-17" version="1">MFSRAPCFRAFTTSTSLHSPRSRTSTEPSASISPGSTAHSSLSSFLDHARRTGLSPHSSVYKGTLFEYRAVDALACLGFDLTRVGRANDRGIDLRGWWRLPSAGGGGGDGGAFTGDTTQADVPVVAQCKADVVAAQPRAVRELEGAMAGAPPGWKGDGVLGLLVARGRATAAVRDAVARSRRPLGFIAAQIVGRIVHFMWNKAAAEGCGLIGYGVALKRSADASDGGEVVLTRDSRVVSVKKRRKRMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7R3</accession>
    <name>A0A6A6P7R3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Copper-transporting P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_281784</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7R3"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000068">
        <property type="entry name" value="Copper resistance-associated P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF32">
        <property type="entry name" value="COPPER RESISTANCE P-TYPE ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="674"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1025"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1062"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="168"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2459868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1115" mass="120102" checksum="79D404FB6F144DB3" modified="2020-06-17" version="1">MRNHQRHIQQCEQCRSEVLGLGASVETGLYPVESTTSASQLVCSEKIQSIQHAEDVPLSPFSENTDPEKAFVAVESPKAPLLFKGTFGITGMTCSACVGTISNALEEFSWIRTVDVGLLTNSATIVFEGKEHVDEIIETIEDRGYDASLDELDEVKLKEKQKGRSDTWKAALSIDGMTCSSCVGNVTAVVQNHSFVKHVDVNLISNSAIVVFDGRDHLGEITQSIEDAGFDVVVNDIARSSVGEEVEDIERTVAIRVKGMYCHHCPSKVGSALSSAFGSDVRVETPLALGNELLKIKYLPRPPDLTIRNIMHTIGAADRNFELSIYHPPSLEDRAREMQRRERRHILLRLILAIAVAIPTFIIGIVLMSLVPKDNPSREYLMRPLWAGNISRAEWALFILATPVYFFAADVFHRRAFNEIKAMWRPGSRTPFLKRFYRFGSMNMLMSLGTSIAYFASIAEVGIASQRAKHSTMGKSAYYFDSVVFLTMFLLIGRFLEAYSKAKAGDAVTSLGKLRPTEAILVDSAFGNDHKVPLDLLDVGDVVRIPHGASPPFDGTIVEGQTSFDESSLTGESLPIPKAVGDTVFSGTVNKGGPVTVQLTSISGSSMLDQIINVVREGQTRRAPVERVADIITGHFVPFVVLIGIVTWIIWLSLGLSGTLPDHYRDSSAGGWPLWSLRFAIAVFVIACPCGIGLAAPTALFVGGGLAARHGILVKGGGEAFQEASSLDCIVFDKTGTLTQGGDPAVTDYEHLAGDNDSRLLGTAKKMEEGSGHPVAKSIVSFCTSRSAESVEVVGIDEIPGKGMKGRFKVGGNHSIAILGNESLMADHSVHIGPEATERLKSWMQQGKSVALLATNSTIDAQEPWILSAIFAISDPLRPEAGPTVQALQKHGVAVWMLSGDNPTTARAVGAQVGIPSDNIIAGVLPDQKAEKIEYLQRSLEKRNSSRSPFSSIRRNRQSTKAHATVAMVGDGINDAPALATADVGIAIGSGSDIAMSSAAFILVSSHLTSLITLIDLSRAVFRRVWFNFGWALIYNVVAMPVAAGVLYPVRTGSGGHVRLDPVWASLAMALSSVSVVSSSLLLRTKIPGVGFRAREPVDVAAGRDEEKCACVARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7X5</accession>
    <name>A0A6A6P7X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="9">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="9">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="9">HAD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Biosynthesis of nicotinic acid protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA1</name>
        <name evidence="11" type="ORF">BDY21DRAFT_337403</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 3-HAO family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="9"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7X5"/>
    <dbReference type="OrthoDB" id="204928at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000093">
        <property type="entry name" value="3-hydroxyanthranilate 3,4-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497:SF1">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="25482" checksum="AAE0DE8B0ADFA591" modified="2020-06-17" version="1">MRGRTYMQLFRPAALQGARQAVRRPPPSVVSGGVRTTAGRQQRAFASTPRSRALASPLNLPKWLDENSHLLKPPINNYCVYDDHVTVMIVGGPNERTDYHINETAEWFYQYKGNMLLKTVDNGRFRDITIGEGEMFLLPPNTPHNPVRFADTVGVVLEQKRPPGSLDRLRWYCQNCGEKVHEAAFHCTNLGTQIKEAVNRFKEDREARMCKKCGEICDVAPRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Y0</accession>
    <name>A0A6A6P7Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein transport protein SEC9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_369939</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Y0"/>
    <dbReference type="OrthoDB" id="18679at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15857">
        <property type="entry name" value="SNARE_SEC9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15886">
        <property type="entry name" value="SNARE_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000043">
        <property type="entry name" value="Protein transport protein sec9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000048">
        <property type="entry name" value="Protein transport protein SEC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="407"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="470" mass="50103" checksum="9D49C5892B1E757D" modified="2020-06-17" version="1">MKKFGFSKKGDRSGDDASSLSSGPPADDHQRSALFGSRGGKLSKSGSGGAPNPYAQQGASPAGTPDPYSSGGGRPAMRSNPPSYSSAGSSAASGSMDRFWQDKSPVPPGGYGGGGYGPQQGGPGAGYGGSRYGSGGGDAGGPGGPQRSRYGAGGYGGLGRSNSQETMNTEAGREQLFGAAPQRLQQQQVAQQPYTYGRGGGAAGGAGGRYGAAGEEDDQSYSSQGYGGGARYEDRQLTEQEQEDEDVDAAKQEIRFIKQQDVSSTRNALRIAEQAEQTGRDTLGRLGQQGENIHHTERNLDLASNQNRIAEEKARELKTLNKSMFAMHVGNPFTASKRREERDRNIVDTNQREREARDATRAAAWSSQARQQEFARDARGNPIGPGAKKPNLVERSKYQFEADSEDDEMENEIDQNLDMLHGAAGRLKGLAGAMGKEVDEQNKHIDRIIGKTDKVDDQIAMNRARLDRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P864</accession>
    <name>A0A6A6P864_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_419808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P864"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="419" mass="46065" checksum="BDBEE4A0AC71B5C5" modified="2020-06-17" version="1">MAGWLAGWIGYASLGFGKWPARQDGQAEATVIPVTGRTSSVHSTSHACFGTLICGQKEREALQLGATGASIYSLLRQCYSSTPLLAGDFLGLPLADLDFDASTPKRSPQEEVRRGPLAAKPNGSDSHSTQPLLPRFLPLRLLRNSYITPSPSPKKDLNSNASLNCPGGSEPSEPRPSKPSKLARELERSGKKDRKGKKGHAAEDKEEEEAEDKRPLIDKEPPKEPSEDDLCVVCGEMNTSLLVGPIGAVSFPACDDEHRHCLTCTYDFLTSDAAKFAPPRRGVPGNDDDADRRIAYVLPCGHIETAARLQRLLGDAERLLDHQASKYKRIATTVNPVWRAPGFEAEQARAMLRQWRKGKKRFAEAWRDEQVRDLTSLEAQRVMAVTSKSKMGEKRAAKGCGDDRMWDFINSLPECDDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8B7</accession>
    <name>A0A6A6P8B7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_384491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8B7"/>
    <dbReference type="OrthoDB" id="2590011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="58"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="40159" checksum="3A52D5B9AF8C6FF3" modified="2020-06-17" version="1">MEMHVRTPSSASESNSARSPLANFPFFKNLTGEKKVTRDGQPPKRRGPKPDSKPALTRRQELNRQAQRTHRERKEAYIKALEQEVLRLKEIYATSTKERDAIAEENRRLKELLAQHGIAFDMNSPPLSSVPSNAGGGFVRGHSYGHSSSGSISGSYGPGSASTGFTSPPGSLGPPSVHTPQMTMPGSGPQGQQPHPQQQNQLDYDQIGIDFVLTLERPCMDHMQMLMVRSADSEADDVSGHALMATCPPGSHIAERPDEPYPHQMPDGLAMPDLLRLLDLSNRLPLDGEITPVMAWAQVLAHPRFAELTREDFATMRDDLGSKVRCYGFGAVLEEFEVRDTLSSVLATKPDSYHNARYGYDVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8C4</accession>
    <name>A0A6A6P8C4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_408288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8C4"/>
    <dbReference type="OrthoDB" id="4117770at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="710" mass="72267" checksum="0DD6BB007B37E390" modified="2020-06-17" version="1">MSRPGPSHPASPRIPRLAVRGRDAPADPTTTSPLSPLAPSNDPGPGPPPPAPWDDIVLPALPASSHGAAPPSPAASSSLDARSPARPAPPPPTAATTAPASRASSLLGSAAGADNDGAGSAPRSEAGSRASSGPSASASTSSSSTRAKEHQQQQRQRKKDGGGGMFSFLSLKEPSASAFEDFKKAQLRQAAEKQAERGRAAPAEARRRRRPPPLAQPLLLPGVESRRLPATVPPVNARWDGLPESARARARRDAAAASASASAAPRSRHSHRSDRTGASSTSSGASAVTTATTTATTTATTTTTATSPPTSAPPATATAAAGFARVPSPSSLDDLPEISYFFPADAASGGAAASAPASASLAPAPLSAPPRARDGRLLRSSPAAAGAAAAAAAAAFLAGEASEMQMPDDRSSTLGPDSEDGGSSVAPTTSYAGSVRSGFSAAGGTEGRAEEDDENDERAELYADPDAARAVLRFQEEQQRPDGTEPDGRGQPQPASSSPPHRVSNRASTDTLTYAYVHPETAVALSTDQATHAYRRHRHRSSAASFAASPHQLRLRQQQQQQHPRHSALPAARRRAGSGATATPDDDGADGAADDDADDAASLYAPSVAAPSLAPSTATATTARSALSAQWYLSPRERLGLGGRVRRLEVRPWEEEPDGAEGGREGAGGAGWENWPLGPGVEAEAGGACTFGMSGDEGRKNAPFSRVMAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8I9</accession>
    <name>A0A6A6P8I9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_384532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8I9"/>
    <dbReference type="OrthoDB" id="5356476at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="409" mass="44264" checksum="4668516D2153F7DA" modified="2020-06-17" version="1">MAAQVDQADPAAAGAAPVDPSMATAAQIPLQTFTIPDFPRQAGSLKALTLTSDIKLDEYSNLVAKDAAFTVPESLPRGIESLTLELFSLGYPPGFLTQLAARLPYLKSLVVYSQLLGGVSPESQDDALRFVDAEPHLRALHLLDVFAKPGFFSRLGESLRSEGTRGRGLMFLEVNYSFRHEDEDFLTRVQGAELPGLVAPGLITCAFNIAPPDVTDDPEDPANLTSEGEPLPAEQRRKEGVMAFNRTLAPALVDALTAEETAPRNLKVLNSTLYTLTTESLGKILGAHKGLMVLSATVELEPTEQCKKELLGMLGKLETLEQVEIVGNPSLEFYLAVHTPKNKALDNVFPSEEDMKALAEKCPKLSNFKAGILRTTSMGTVEWTKKGGKWNGGIVYPDPPKEESKEASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8J3</accession>
    <name>A0A6A6P8J3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_280483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8J3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF103">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="511" mass="56929" checksum="008FA1B9FD6C5FD9" modified="2020-06-17" version="1">MATSSLLFGLGAPLLLSGLTLLLCCWTVAQVVYCRYFHPLSVFPGPFLASFTNLWKSYQVLLGKYEDTLLKLHRKHGKLVRIGPNHLDVSDADSVKNIFGAGRTYPKSTFYDAFTALRPNLFGTRDEQVHSTRRKAVSNSFSAQSVASMEVHMDRCMEKLIRRLDSAAENGEAIDIKLWIAFFVMDVLGELAFSRPFGVLDSGDEYQMPPVREHVLLATTSGQTPWVVPYVNSMVPHVPVPSLQRMVRGRKDLRQMAIDSVNDRLRSDSTRIDLLGRLLDELKSGVDSKGRALDVVDVQTEAFGFIVAGSHTTAASTTLLLWHLLRNDEAFAKLRDEIDSVPRPSSPSYPYSSVKTLTYFQAVVDEAFRINPVFVMPLMRVVPDGGRQIAGSYIPGGTDISICNHALHHDDSVFGPDLERFLPERWLQPGYDKHAYLMPFGGGHRACVGRNIASQEIYKIVASLLARYDISLALGSASDGMQRMPQTKSFGVADLDERFMVELKLRTPIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9E3</accession>
    <name>A0A6A6P9E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_166342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9E3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025504006" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11209" checksum="E6FF744E891E8BEB" modified="2020-06-17" version="1">MNIPMAFNFLLTLACLQYSVSTARTDGRASKKSSSSTKNGWTYVVGLECTSSNFGVGYTRTKLQERNKSRMRHLYLPETYCVLPSRTLRLGALKEQTYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9F0</accession>
    <name>A0A6A6P9F0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heat shock protein-like protein 70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_335915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9F0"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000021">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="617"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="652" mass="70929" checksum="756ACDB6B8308D47" modified="2020-06-17" version="1">MAPAIGIDLGTTYSCVGIFRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDSAKNQVAMNPANTVFDAKRLIGRKFNDPEVQADMKHFPFKVIEKSGKPVVQVEFKGETKIFTPEEISSMVLTKMRETAESYLGGTVNNAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKTQGERNVMIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHFVNEFKRKHKKDLTSNARALRRLRTACERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCQDLFRSTMEPVERVLRDAKIDKSSVHEIVLVGGSTRIPKIQRMVSDFFNGKEANKSINPDEAVAYGAAVQAAILSGDTSSKSTNEILLLDVAPLSLGIETAGGVMTPLIKRNTTIPTKKSEVFSTFSDNQPGVLIQVFEGERARTKDNNLLGKFELTGIPPAPRGVPQIEVTFDLDANGIMNVSAVEKGTGKSNKIVITNDKGRLSKEEIERMLAEAEKFKAEDEAEAARISAKNGLESYAYSLRNTLNDSKVDEKLDAGDKEKLRSEIDKTVQWLDDNQQASKDEYESQQKELEGIANPIMMKFYGAGGEGGMPGGMPGGGMPGGGFPGGAGGRQGGDDGPTVEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H1</accession>
    <name>A0A6A6P9H1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_406348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H1"/>
    <dbReference type="OrthoDB" id="5312133at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42055">
        <property type="entry name" value="YALI0E03476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42055:SF1">
        <property type="entry name" value="YALI0E03476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="667" mass="73952" checksum="C5D3ECB93D92D554" modified="2020-06-17" version="1">MPLFPTAGPNGQRLSFSLLPRRIKLVLGLAIFCTTLLFIFGAPSSPGHYRVPTSDDIIDTIAHPGSKLPGLPNLPHRINPFAPPAHKPPPEQANSTSGETRWFSDWKWRNPFSSSITLDENRAVLPPLRKRTPIYTFYDAMAAGGKEKKSEGMRRAEERLLLAWRRAWWAQGFKPLVLGRPEAMNNPLYERVQRMELDPAMEVELMRWLAWGNMGRGVLANYLALPMAHHEDHMLSFLRRGEFPSVTRFEGLESSVLAGEKAAINAAIVLALDDPEIVNKKSMLDAVPKETISIDKDATGVAFYDRKTIAKKYKPISTKLDSVDTAADGLADLAVLVNAHLHNTWQNTFSNGVAVLNPLPERMTTLLDPAIDIGRNLTTCPASPIPSSCPPNKPKCKPCPAMHPLRLAAQKSFRNSTTQFTIGVVPHPWTTTVMAHLPPAADGVFDARFVRRNTTRDAWLASATKDLLGTGIGAPSRALRFKDVVASEWGTAHTLWLTAERPSARDVEWVLGFALPGLDPPDRGTSDTPVPGPERKPPPPPSDLPDPVSPEEDARERALLRKARDAIKSKVKEVARLREAVEAWNLADTEAWRFARAFGARRRVEREVWEEEERKFAGAEERVDGWGSLEALKTQNGSQLLFDHRAADRTSDTTFKACGMRHSSLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAH1</accession>
    <name>A0A6A6PAH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative cargo transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_133699</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAH1"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF1">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01339">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="303" mass="34068" checksum="08829D5FBD9129A6" modified="2020-06-17" version="1">MAQIRGTAGYHLGGQNPFTGPGSASATNDPSPLDAIREQTSKIEDWLDTIADPVKPYMPAIGRFLIVVTFLEDALRIITQWNDQLIYLRDYRHIPYGITHLFLLANVIVMSICSFMIIVRKHSDYAVGGLLGVIVTQALGYGLIFDLNFFLRNLSVIGGLLMVLSDSWVRKRFVPAGLPEIDEKDRKMYFQLAGRVLLIFLFVGFVFAGQWSFWRILVSVVGLVACIMVVVGFKAKWSATLLVVILSIFNVLVNNFWTLHPHHPHKDFAKYDFFQILSIVGGLLLLVNMGPGQFSVDEKKKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAL5</accession>
    <name>A0A6A6PAL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_361010</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAL5"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="569"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="773"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="302"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="953"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="973"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="986"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2460990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1180" mass="130735" checksum="8C0EDDB2F14B811C" modified="2020-06-17" version="1">MARDNNRSPSPAGSSYSKRSGRRDDDRQRSYRRRSRSRSLDRRDRDTRRRRDRSYDRRDDGNSYRPGRRDRSRERRRSRTRSPVKDRGDRDRRRDRDRDRDRDRIYNRRRDESRDRHRARRDDSPPRRKGRPNTPQKEKEDPAKAAEIAAAKEQAEKERQKAERLAKLEAWKAKQAAERKRKEEEAAKGGGAQGTRALLAEMDKKEAGVASPSAESAMSPALPSGSASPAPYAGKFDPKAIARKAAGGANNSNRLGDVNVPHKSKGTFIADLKPDAAKANGYSHPTIPPSLRRLKAGEKVSGFELGAKPGPDNEKIGNKTALDFDEEETTRKKLEKLPQFDLTDAAYANTADIDGDEDDDVEMGEAETEEEAAAAARIAAEKRDERLQHEIEAEAEAAKRNGEFPQTVEPGTSAEKTEGAADDEVDPLDAFMATLGQDDQQTQTKTKKSKLEPEAMFNDEDMMDAVDEGAEDILALTKKKKKEIPTIKDTSWQDEPFRKNFYREPQELAEMTDAQVAQLRHDLDGIATKPSNTPKPANKWGYCALGAQVLDVIQALGFEKPTPIQAQAMPIIMSGYDMVGVAKTGSGKTLAYLLPMFRHINDQRPLSKLEGPIGLVLTPTRELATQVHRECKPFLKALQLRAVCAYGGAPIRDQIDQLKAGAEICVCTPGRMIDLLTANAGRVTNLRRVTYVVLDEADRMFDMGFAPQVRMILAAIRPNRQTVMFSATYQGKLDGTAREILSKDGSIQVLIGGKNVVPPEITQIVEVRDASTKFRRLLELLGELYSTDEDARTLVFVERKEAADVLFKELLNKGYPCQPIHGDKEQIERDQTIADFKSGALPILIATSVAARGLDVKQLKLVVNFDCPSHTEDYVHRAGRTGRAGNKGTAVTFITPEEERFAFGIIIALKESKVEPPKALARLSNKFNKKYKEGEVFRAAGGFGGKGLQHLTAEREASRKQTKAAYKQAGGGGDEDDEDEEEEVEESPKKPEKEFEIKSTAGPSAPPGPSASAPPAKELDFEGNNIVVHKTERPAAGQSPTNPLDRVRAAVANIDNRLTQKGQLRHGQPIDNKGPDAGAFHATLEINDYPQKARWAVTNRTNVAKILEATGTSITTKGSYHDPTSKNPPPAEPKLYILVEGDTEIQVRQAMTELYRYLREATIAAADIETKNPSGRYSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAU2</accession>
    <name>A0A6A6PAU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leo1-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAU2"/>
    <dbReference type="OrthoDB" id="20844at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007149">
        <property type="entry name" value="Leo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146">
        <property type="entry name" value="LEO1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146:SF0">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN LEO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04004">
        <property type="entry name" value="Leo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="469" mass="51782" checksum="51321584AE1C46AC" modified="2020-06-17" version="1">MSSSEGESAASDAGRPVHSVEDDQAEGSQLENDGGDGIEDDDLFGDGEDDDADFDHEPVKKRQLDDEELDSGDDDGRNDRAAAAGTPDEPEETSTYKYVTVELSRNGVPEPSDNELYLFKVPTFLDIEPAAWNPRTFRPPTIDNRSKGGAPSESFSPYTTAMSAIRWRRSPSNPSDLQSNARVLRWSDGSLTLQLASDPLNQFEIDSNPLAPPQYNPPKPTPTSRVAKRGQPPYDPSKDSFTYLCAPSQSAGFLRVTNKITSGLTVTPPADSTATNQAIQRLQENMAAAIRARDPEANGESTLVTIDEDPEKAKREAEQAEKDRLRNQRRREAQEIRERERSGRAMARSGIRTYGGGAGAGEDGRSRAKGHRASRRDDYSDEDEGFGRGRARQDEYDEEDDFIAGSDEEPEIVEDDEDEEELELAPRTKKTSPKRNRPAADEREASDEVAVGGARSKRRRVIDEEDDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB36</accession>
    <name>A0A6A6PB36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TRAF-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_135839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB36"/>
    <dbReference type="OrthoDB" id="1630758at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02176">
        <property type="entry name" value="zf-TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TRAF-type" evidence="6">
        <location>
            <begin position="80"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="80"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="351"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="407" mass="42836" checksum="35177D60D0FDAB3D" modified="2020-06-17" version="1">MLDELVVKCPNGNAGCAWEGKRGEVQHHIDLYCDYTIVECPVPECRLEVLQKDFHRGCLHYGVKCEDCGEGMLKRDLDDHHNSSCPNRFEHCPHCSESVLKRGLTAHVSTTCPVGPTNCPGKAYGCTFYATRREVVEHSKTCQIAIMTPFLVEQKQLADEQRTANELLRRKVKILEGGFTAMQGVLYSSDQQSQHHQQGPQSSRINPATSPGVAASFQPLDNAVASPAPSNSVSAAASTPHQPSTSTSVSPNASAHASPALAPNPQPNSPSLPSFVDAPTQHLLSLHESLREELARQQAALADLEARTTVMILNEGLRAKEDMAHTNAAIGAIRMQMHWLMSANARFAQGGGAGGGRGTAGATPAGPSRGAGAGAGAGSGAAGSAGGGGLLGPARRSSDSGRQDTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBC5</accession>
    <name>A0A6A6PBC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_278664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBC5"/>
    <dbReference type="OrthoDB" id="4177236at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="143"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="377" mass="42334" checksum="0796671D474E07AE" modified="2020-06-17" version="1">MDHPKDLTPASKPSRNRVTKASCNTVAARWNLKILRALESTLKKDPEADIARLLPSTYSGQLQSLKSPETKPKPSFPSNDIRSRLDATAQSAIIFDLSSELEDLRSGRDLSEALVDSLAEGEVLYESAWAASVMVFRISENIVVKVTDEASAMTEHRTLSYLRERLPDFPAPRPHGVVRLDTYFLLFSTFIQGVDLEKVWPQLDEGQKLAVSSQLDSLFSQLRALPFPDDTPLGGIQGDGCKDCRRGVRVSSEAIMDVGQFEDFIFAGLNAASSLYADFLRSLMPLSSVCVFTHGDLRPANIIVDTGDDGTWKVVAVIDWESSGFYPEYWECVKMTNNLTPRDQFDWYRYLPKSLAPHRYAIQWLVDRLRDRSMVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBE2</accession>
    <name>A0A6A6PBE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_361097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBE2"/>
    <dbReference type="OrthoDB" id="340227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048255">
        <property type="term" value="P:mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006607">
        <property type="entry name" value="DM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21071">
        <property type="entry name" value="LARP1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00684">
        <property type="entry name" value="DM15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="709"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="803"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="872"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="941"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="600"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="847"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="943"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="960"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="975"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1166" mass="126703" checksum="2F5DC5342B254979" modified="2020-06-17" version="1">MASLPRKTGGEPAQVFSYAQAAKGLSSKASDASASQSQSTKPSPGGAVTPSKDIGAIPSLPSGMSWSEDAESNSAPTGTGSDDTVTDKPQVNGTSPQQGSKDAPIQSAPNASSPASPDLAGTSSSSTVAKEDDISSLPNASSESTWENKSQVSNTMDKPADQPESAGDKAKSDEKKEKPAVKAFQPAPVPPVNIWKQRAEEAKARAATQTNVKAPTPAEAKQAPIPVKQTESGKGDSHKRGPTSQPNKKSTAEASKAEKVEDARRGSKTGADVEKTKKGSAQKNEQEDKPNEMPPPPPTKDQEAWPTPENAQDEKKRVQDKGDKADKETKLAVPSKSQGKSEWKPVPFTPTVIFNTPLPNTNSRRGGRGGGRGGREAGGRGGSYNSGGNVGSEKGPSPLPNAANGDSRRSRMDSASVEEQAAKNKRTSSAGTNPPKEMRQGVAQISDRTTKTFAHADAKDSTAQPSRRPNLDEPASLNSTPQPSHSVRSTPGGRHKQSRRFDSGANTTDRRKDVEPAYLRNQSSSPTGMRRASIATSQTEETMDRRASVVSDAIGGHNSRGGPSDRRGGPFGSLPSRDRGEPRARGSMRGGRGAHSYQGSHNSTSHTFSSSQSTHLPPLQTSTPYNLPRSPQVFTPEQNSFFAPPASSTQRGYRGPAPRSQTLTNDNVYGRQPAPYSAGPHGMPQYPMYMGGMYDYNMQPMSAHPFNAVTDPWSLCSLVTLQLEYYFSVDNLCKDMFLRSHMDSQGFVFLSLVADFNRIKNLTVDLELIKYVCYNSRYIEYRIGLDGRDRIRKHEGWEQFVLPKQRRDPSVQNEGPSELQYPPTPHPQTFEVPYGMQHPMSPVGGPTSPTSMPQEQYNSLNGMASVPTSVAPIVNDMPPPSAHQVDSKSTTGGPTATPFVPAAAHQFPNEPNSTERDSFSDERIENLGVVVRYQDPAVVQGPNLPSASRTFSNGSIDSHGIADEANKVDGHPNDPQVNGHATQDQAPTTALTSPTSQTPSGNQVQLYWVKDHEQPTETVPAGSSYELYTHLRVKALEQRQNSPHGTCPYDMDVLYQFWSHFLIRNFNMRMYEEFRRLAFEDMNHRMSDIGMHNLIKYYGKALLSDNPIRDRVAQHYVELVKTENPEPPRPAFKQLRSAWRNGALNLMNRKKIITFVDNDLKAALEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBG0</accession>
    <name>A0A6A6PBG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBG0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17299" checksum="337808D8F0144824" modified="2020-06-17" version="1">MPARRRVPADLSQTDFDMEERANHSPAETQRQDPAVGRCLRRMFGAAVDCSAKTVVPGPPRVLADRPKPGQGFPTHPGAAMLKSPSQPACAAREHGPLSVWIVLFPSRPDFIFLRVPMTASSDWATRRARAAGKRPSGANANYAVAGMARSRPCLAQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBG6</accession>
    <name>A0A6A6PBG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">S5 DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_315235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBG6"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000041">
        <property type="entry name" value="37S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="281"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="445" mass="49384" checksum="51F37834E31704AA" modified="2020-06-17" version="1">MSVSRPAARCRCLFSMPPSSVPKPHPRRTFTTTPPLNRRVRRGYKNIKAEDMGLINKAAAEYRPYSEEEKALLSKKYNKEQMDAIEAAEAEAATILGEGSESSSSSAITGIDPRDLATQAGFRRDYLRLGYVDDLSRISPVLDKRKSKEVPPNMKTNALPPSEEKLAEQLGEGLDSLLDRDPTVQAYFENNSEGRKVDPSTGKPTPETQVVDELIQSQIHQLERNNLYVDPEYSALAPDIPRVQDPRFVYESDEAETGEVDPDQQRVRRAIGMSEADASRFMQKVLVVRWVANQTRLGKVRSTSALAVAGSAQDGLLGIGSGKSVEPDQAMKQANANALRNVRPIPKYEGRTIYGDVQGKVSGTVVQLMHRPPGFGLRCQHLVFEMARAVGITDLAARVPRSRNKMNVVKATYQALMKQKLPEDVARGRGRKMVDVRKVYYAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBJ4</accession>
    <name>A0A6A6PBJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_297819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07199">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="734"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="11">
        <location>
            <begin position="800"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1290"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1364"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="8">
        <location>
            <begin position="804"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="8">
        <location>
            <begin position="838"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="8">
        <location>
            <begin position="987"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1304"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1319"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1335"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1433"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1481"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1530"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="840"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1539" mass="174585" checksum="9F0C6003F5BDDD60" modified="2020-06-17" version="1">MDLSRNRSAVSHHRPAAQIPSASSVISRSTSPEPSRVNRMSYSSLRTLPYSKTSSSPQEMLLPPSRTPPTPPMSLMHTSHDQGFIFPEMRSSQRPCEICGLGDKQTFHCVNCDTVYCGVCWDMQGPHKPGKVGPDGLPHEKADLKVVNRLREILTPSNDPHIQQAMHMSDEDTTWFGVSRDATGSPIFQDHGRYSTLMADSASFEHRVRYPQLVSFIGQTGAGKSTLVKMLIEEQKSQVHPSKRVAFPSPVVGSAQNDNVPTSGDVHLYADPGTSFGICPILYADCEGLEGGENIPMGNRHRSHSQADPKDKPDMKPETHSPRKRNKISRCSSRGLLWATEPETRKRQYAVTELYPRLLFTFSDVIVFVLRNAKVFESSVLGKLLRWAAASIEKSVNQPTLPHAVIALNATEIGIDQREWEVEFSTRSLMETVADAVRRDPKYAEYTDFWTRRGKSIRTMKDLLGCYFSSITVVRIPNRGGGRYMLIDEQVGKLRKVITTKCELSYYAKRKARMLSSSEELNVYLQCAFDHFANDLDTPFNFIEVAFKNNPIPLDFGGNILKLAVAMQRVNQYEAQQIFRRLAVMVASCVMLDCVRHSIKGDPGKVLEEQYLDHCDSALIDFCSFFLQCSYESPRGERCIVSREGHSKGHQNEKGKFIGHGNFSSPFSFEKFQDEWLQHLTENIERFQQRLQDSMHRNHHVPEIKVASQIHLDWVNDFFRSLGDPRKFVSHSACFCCLREMPEHPLPCGHVICPECAKAYALPKRECNILLDSCPLHSKDTFQGRYAIQTKPELAGVRVLTLDGGGVRGVVELEILREIERQLGDKIPIQDFFDLIVGTSTGGIIAMGLGVERWSVNSCIERFTKLVDKAFTPKFASLRLNIRYKTRPLVQALQQSFKNENLFGGRRDGYTSYHAKVALTSTTETGDKPVVLTNYNRQGEIQPMYEFVRPDDPTHELKLWEAARATSAAPTYFKPFVNDRTNEGYIDGAAYYNNPIRVADHERKLIWPELANQHPDIVLSLGTGHNGNRTRGFVDPSCRYFGHGSDEDSVSDTRSFRNAATGWRKWTPLLNIMVSRGESLLDSEREWQTFRNEKFSTNSTLDSRRYQRFNPMLSSRTPHLDEKSQVPNLQAEVGDQLRRKPPYQTKITQVAQRLVASCFYFERLTPTKELEDGFACGGRLRCRFPDGSQNLRYLGDYLRNHQDPTFQPYFTVQERCYQPVKYEISPDVVHNMIVKATFDMGIMEIRVSLQQGHTSISLCLRRWNSRSVEEHPISGFPRSLALEDLIKNVHSEPKPQPSLDRLRQNRHRSFRHRRDNSRTEIPQSQPDPQQQENTSQSSGSPSGRSRNSDEDRWGFNDWILRRERSGRPPIFGNTFRRSRDPRPAPTNGGSTTTSPVVAPAPSVATSGNTPEPGAPRNVSSFPLAPELEEEDDRQLRQAIERSLLESQEAAREERRHHLAARKVATLAPPYSAELPVPEPPVNDHQEQSRPRREEAPAAPIGVQQRATPEQEEYTRPKRTGSGTDPEELEEALKRSMIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC17</accession>
    <name>A0A6A6PC17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SAM-dependent RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_278766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC17"/>
    <dbReference type="OrthoDB" id="373498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18090">
        <property type="entry name" value="Arginine_MT_Sfm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007364">
        <property type="entry name" value="SFM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517:SF1">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04252">
        <property type="entry name" value="SFM1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="205" mass="23185" checksum="0DEF909C06708CA4" modified="2020-06-17" version="1">MEPKTYVVEHLDPELGEWSTLEYKAIARESYESGARFILSSVPEELELPDDLKSAEGLSVERTSVEVLYEGKKDKVCLLDPQAPKELSPTDGDMFDVFLFGGILGDDPPRDRTSELRKKGFEGRRLGPVQMTTDTAVRVTRLVVQDKNPLEGIPYVDYPEIKVNRHESVEMPFRYVQGDDKAPVMPTEMAELIKRDSEKGFGDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC61</accession>
    <name>A0A6A6PC61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="2 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_376470</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="2 12"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC61"/>
    <dbReference type="OrthoDB" id="3000483at2759"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005971">
        <property type="term" value="C:ribonucleoside-diphosphate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.70.20:FF:000001">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="14">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="768"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="830"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="926" mass="102835" checksum="6CB17CB03ACEBD68" modified="2020-06-17" version="1">MYVFKRDGRKERVQFDKITARVSRLCYGLDPDHVDAAAITQKVISGVYQGVNTVELDNLAAETAAYMTVTHPDYAILAARIAVSNLHKQTKKQFSAVVSDLYHYVNPKNKKPAPMISKGTYNLVMKHSEELNSAIVYDRDFNYQYFGFKTLERSYLLRIDGKVAERPQHMIMRVAVGIHGEDIEKAIQTYNYMSNKYFTHASPTLFNAGTPSPQMSSCFLVDMKEDSIEGIYDTLKTCAMISKTAGGIGLNVHRIRATGSYIGGTNGTSNGLIPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHADVFGWLDLRKNHGKEEVRARDLFYALWIPDLFMKRVESNGTWTLFCPNEAPGLSEVYGDEFEELYARYEAEGRGRETVRAQKLWYHILEAQTETGNPFMLYKDHANRKSNQKNLGTIKSSNLCTEIIEYSAPDEVAVCNLASIALPSCVDVTRGVYDFEKLHEVTQIVVNNLNKIIDVNHYPVQEAKNSNMRHRPIGVGVQGLADAFLALRLPFDSEEAKLLNKQIFETIYHAALTASCNIAKRDGPYTTYEGSPVSQGILQYDMWNVTPTDLWDWDALKAEIAEHGIRNSLLVAPMPTASTSQILGFNECFEPYTSNIYSRRVLAGEFQVVNPWLLKDLVDMGLWSDNMKNRIISEGGSIQRIPNIPDDIKALYKTVWEISQRTIIQMAADRGAFIDQSQSLNIHMKEPTMGKITSMHFAGWKLGLKTGMYYLRTMAASAPIQFTVDQEQLKVADTNVARQPGAAKKRAITAGSYTSTSPASAVPRPMYNNGAGNGRGAAQASNGILTAPATPSPTAENKRLSTGSAASSTASPKKGVPISAPPFKADVEEGDSPKLLSTDPTGEKPKDEELPEPAVTQRANQEEDSEEDSKGREGDIYADAVLQCSIENKEECIMCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCF3</accession>
    <name>A0A6A6PCF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_88958</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCF3"/>
    <dbReference type="OrthoDB" id="5411678at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="397" mass="39800" checksum="8D3BFBEFF928E2A1" modified="2020-06-17" version="1">MPGTMASSADSNSPTASVTGIATSTEQTSVSDSPSSPPPETTTPTTTPSSAPTTAPTSSANFVDTSSVIASAPPPSTELITSAITITPSTPGDSSGAVTVVITSVNTPTFSIPSNDPATQTAQSSASSSTGAAALSPDEDDDDSSGGLSPGGKTAVAVVVPVVVVALLVLGGLFLWRRRKQRKNAEEARRKEVEEYGFNPNHDPTLPAVGGVTTSEMEDSSGYRGWGNTTNSSQKAGTTLSGGGMTGAMSDSASQPGGYNPGSPTQGAPSDGHSGEPLVGRRNTMDGEVAGAAAAAGAAGAAGAAGAGGVQRGPSNASSSYSMANHSDNSADAPIPLHSGQEYYSDTGYYQGGPYDNQYNNGGQQPIIRDVQARRNTRIENPSIFPQPPNAGIAQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCK8</accession>
    <name>A0A6A6PCK8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">diphosphoinositol-polyphosphate diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_314238</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:79699"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:79700"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:22385"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein-tyrosine phosphatase family. Atypical dual-specificity phosphatase Siw14-like subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.52" evidence="2"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCK8"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052840">
        <property type="term" value="F:inositol diphosphate tetrakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000035">
        <property type="entry name" value="Tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="6"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19755" checksum="FA145B1FA64F7798" modified="2020-06-17" version="1">MAVPPNYGAVVPGNIYRSGFPGAEHLDFLKSLKLKTIITLVDTVYPESHTKFLGENGITHIRVVLPANKDLVEMTLEQMCKVISYINTPSNWPLLIHCNKGKHRTGCAVACYQQYVNGKKTVDCSLEEYTTYAGKKARKMDEMFIEGFDVFAASGLILGMSYQPLGGTEFSLCAMEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCQ6</accession>
    <name>A0A6A6PCQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_92371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCQ6"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF76">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="675" mass="72422" checksum="3942134C52D0D4D1" modified="2020-06-17" version="1">MTTVVEGVQNGADHSRKDRPAEPPASGFTAVNGRPSPPQPPRTNGMTVGEHRTSPTSTATIATENTSLSPQSAHHSHSLANGYRHASPGKRKRSGSEVNGSNLSQSGGPALETSKRKLESYESDALRERSAPSSVAARHPNFVDPAIGRPPNLRLSHGVSPDSVNPSPWSATSHEENDDSESELAEALQRESRNMDEQQRAGNGESRGISLGHSQAQSSDFSTPITTARTAAGVQVDTKRRKRVFSNRTKTGCQTCRKRKKKCDEAKPECNNCIRGGFVCEGYVSKATWSSKPPMNKIPVALQSKERGGYNPVPIWPSRDPYSADLSAPQAPDNGRARARPAPAEGSSSHDPPRRSWSSVTWQDQNQSPYAQSQPPANEIRQPPSATSTQPPQLPPQPQQAQSQPKETISAERPGSASASRVEAPHVQSSQNNMADPRCSVSMMTSQSALMAQHTAHQALQRAAKTEKEKMRDGEYFHMYDDQLIDEREQCKAALYRYNSNALNPANGVSREERARMFRQILQPGSTAAAATPAANDAGVLGKGVFVEAAFTCEYGYNINIGDDVVIGHNCTILDSARVSIGSRSIIGPNVTIVCTNAHTDPNYRAGSQGCFYAKQVLIEEDTFIGANVTILPGVKIAKGSTVGAGTVVNKSVPPGVVVSGNPMQVKHGVPPRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDB1</accession>
    <name>A0A6A6PDB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDB1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025456750" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="7408" checksum="CE4E013842FFB8A1" modified="2020-06-17" version="1">MRARPRRPLNMLPALAVSGVRSACLSALTSAVAAPVATHWRSLSSARSSDFLSRGYGSSVFSKNCGGGGGGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDB7</accession>
    <name>A0A6A6PDB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein BNI4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDB7"/>
    <dbReference type="OrthoDB" id="5563016at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751:SF18">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR PHACTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="759" mass="79760" checksum="00309F431971B837" modified="2020-06-17" version="1">MAEVLAPLVQQPSTITMLHPSTDALQTNAAPQPNTQPSRASQAQGRAHGYASSPSGGMGYRGTAATPVAPYAFQSTPHLRQDQRSASAPVAPFNPRAAVAAAPPSSSASNSSTASSGRSGPSHQFASQDDLVLDSVHRRSAVGSNFDSRLSSSVSLSTSVPDLSLTTLDAPPKAHPDRYRRAVRRTDAGNPTNSSAQQSAAPSGSGMAAVAHLYKGAPAGTAPSRTGHLRTSSADDTYLPRQGALEQAKRYRRRSISSIDASTLAGAAPMTSSMVPDQQPNKSTNNSVRPSLGHKRQDSGESRSSSSSGHRPSSANAGTPRNATAQPVLAATRNDSKTANVPSRATPDSNKRPSPLSQSAFENDDELSTKGDTRPGSSAAPPSPAVQHLAALSDKDLNKGMKSRLRRAFSFGSSAELRRASAANNLSTSDRQKLHKDRPAEDAQTAEDEEIAARQEAAGIGNSIYSGQGNVFTGSTDNLSISSTASSASVMLRKMGKGMKKGTRSIKGLFRPKSVVGVPSLDSSAVTQPSVAQVSMVTVEAEREKVNVNPHPQDQAGGGTGFPKLERNSIDAASRPSTEQQSSSIGNAASSEASGPRRSIVGGDEERAKVLAAVRKGILKRSGTSSGNSSPVTHPVDAKPPAAEGSLDTPHSSAPSTPDDQPRAMPVKFHSSDESYFVGMSRLSGSTKSLPNTPVRNISFSPRIQFHDVWSSTEYDRRGEIATCNRLTPMLAQQIKEELNSFKMEMEVHELSKPHTHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDK5</accession>
    <name>A0A6A6PDK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_418047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDK5"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="205"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="628" mass="71894" checksum="D79EB95F333809F4" modified="2020-06-17" version="1">MLSPKWTSAPLPRSRTGRKLKKNRPSSVPTTLFSIPKKRAAESEVPEESSPPPPSKVAKTEDGSSPKSSPVPTPAPSRAPSPALSSKGKIEPETAKEPRKETGVPLPRAITEGVTLFAPKVDRPPVCIRPSGPLAGGPTEFPIANWSHENLGWETLDKVDGCRMIPFWHFGDDIEEDGEPDIEGIKKMVRPHLHYCGFDEKDEVTITPFSKGFHSLLFKVSAEGRKDVLLRIPMPLVPWYRMQSEVATMEYVRLNTTVPIPRVYAFDSSRSNGMNLEWMLLEKIEGTSYAKKEPEMSYEARKALHLQVADWVDQISRLRFSHIGCLYRNWDPNSPEYLQFFLGPAVHGDFIYKRRLGYPVHRGPFNNVVDYYRSHIDLTLAEMLDEETRKEIKMDEKRLAGLKENPPPDFNIDDYDAFTEYDAEKLRLLPDYCLKLNSLLPHIHSHGALKELSTSLSHWDLSRRNIIVNDEGRAVALIDWEQVMTLPDMAVGPVPTFVAEDAMDSRYMKPKAENQEEGDDSTSEHPILERHAFYHRLWELNSPFLACDRSQIVPNIRLVQLKLRATRLKDECWYEPKLADIEFLQQWWVRDVFGPHPGKSRVEYEDVESKLNCRNFEANLKRQMDTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDT4</accession>
    <name>A0A6A6PDT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Plasma membrane proteolipid 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_330562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDT4"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="57" mass="6296" checksum="621B8EE97E6E476A" modified="2020-06-17" version="1">MPFTASDICKIIFAVVLPPLGVFLERGCNADLCINILLTILGYIPGIIHALYIIFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFI0</accession>
    <name>A0A6A6PFI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_277582</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFI0"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF29">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="68"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="558" mass="60387" checksum="DD81C43731AECBDA" modified="2020-06-17" version="1">MGLGILESRTASKVPGTVTLDEAAAHSENVTGNLKHGHGKDHHIVLVPQPSDDPNDPLNWSSFQKHVVLVIICFGTIVNGAIPGPLLNAGFVQMSMELGVSVDDLVKTSGYVLLTTGAIGIFASAAARKYGKRPVYVLSSIFAFIGVIIGETASGYDALVASRVIHGFGVAAYESIVVSTIGDLFFVHERGLRVASVIFLLAAISNGTSIIAGVITNHLGWHYNFHILIPFVALQLVLCVLFAPETTYRRDRKYNVDTAGRAAPSEGSSLSNEKDPRAEKVEKVPSTTAEDLHLPPLPKKTFWQSLALYNGTFVDDSIFKMVIACPAILCNVGASYTIFVSGVTIAWYVAVALLSSIIFSAPPYLFAADSIGYTSVGPLIGGFLSSVMMAIISDPFAKWMARKNNGVFEPEFRIPLILVGAICSVAGLVGFGHTVAEGRSVYLACFVWGTMLFGLTNVATTTTAYALDAYRDYSTEIFIMNMVFKNFFFYGVTEYIVDWYTTDGVAKIFDVMGGISAALCFLSLPIYIFGKKYRHFWDKYNVIKMLHLETDKTGADGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLU0</accession>
    <name>A0A6A6NLU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_156867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLU0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="164" mass="18059" checksum="337D422AA1CAD941" modified="2020-06-17" version="1">MSRSVSAKNSKIAPASGVRGTREMTVRQAPSRGPHHRVPGRRFPGRRSWADLLDLIESTRWRPPAAATLSTASAREPRRGRKRSHRTPGTPALVPSQPGKELPGLPGFERAKTNFEAEPDENFLEPAGRAMMQGARLFSSSHPVLGRQIFPWSVGLSVCVYRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM39</accession>
    <name>A0A6A6NM39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM39"/>
    <dbReference type="OrthoDB" id="7289984at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF3">
        <property type="entry name" value="CHAIN DEHYDROGENASE (ATSC), PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29363" checksum="DCCE55E913C5DEA5" modified="2020-06-17" version="1">MPSYLITGTSRGIGLEFVRQLSADPANTVIGLVRDKQATEQRMKEWKRDNIFTIQINDMADYASLKNAVEEASKITGGSLDYAIANAAYVSKLTNYFTFGDLPELIQKDMVDAFLVNVVGVVHFFNLTVPLLKKGTAKKAIALSTGLADDNMNVNFELDVSSPYSVSKAAMNMVVAKFAAEYKREGILFMAVAPGLVDTGAGDMHPNASELEKKRFNETYAKFMAYKNTPPITAEESVKAMLGVFESSKTGTDRDGAFISHLGNKQWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMH5</accession>
    <name>A0A6A6NMH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMH5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="106" mass="10964" checksum="BB60C3FB31C615A5" modified="2020-06-17" version="1">MISPIQPFCDSHTAPLRPRSSRIWLAAPAGKNAMGKNAMGSHMQAGREGLVRAGSPAKPVIHSPGPSASVTSGARPFDGQPAFAADPAIPFRSRAAPGPGRGQFCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMN3</accession>
    <name>A0A6A6NMN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_261269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2453000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMN3"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF13">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="28"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="254" mass="29189" checksum="F973612488E5D030" modified="2020-06-17" version="1" fragment="single">MALIRLLQRKPDGDIVFREPTSGHIPVYAILSHTWGNEEVTFQDMEANADTSKTTSKTVSKAGWKKIQFCADQAAADGLQYFWIDTCCIDKRNAVELGAAINSMFRWYQNAAHCYVYLEDVSKPDGADDERAWKEAFRSSRWFTRGWTLQELIAPRLVDFFSLEGQRLGSKLTLETEIHEITGIAKNALRGDALSNFSIKERRSWAERRNTTIEEDGAYCLIGIFDVSMVPNYGERRDQAFRRLEEEIHRLYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN08</accession>
    <name>A0A6A6NN08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Complex I intermediate-associated protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_388276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CIA30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN08"/>
    <dbReference type="OrthoDB" id="42561at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010257">
        <property type="term" value="P:NADH dehydrogenase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF18">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="5">
        <location>
            <begin position="45"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="29661" checksum="5221E1B26976E368" modified="2020-06-17" version="1">MRPTPRLLRRPGFVRRSLDEFLRLSNVAVNLEGLREATKPYHLVSFDSPASIDRCKTMSDRDIGGFSTAHLDFVPGGSASTRDTHHDADAPPHARFHGRISTQLPASSPQVQRTGYAAWRTLDRGASLWGRLLWDTSPYRYLALHVKSDGRAYFVNVQTDSVVPTDIHQHRLFAQRPGEWETVLIPWDDFVRTNYGRVVEPRHEMLRQKVRTVGIGSTDRVVGPFELRVAGIWATNGLEKERGETGEVEKIRGEQVRWTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN83</accession>
    <name>A0A6A6NN83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD repeat-containing protein 82</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_417380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN83"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="116"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="290"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="365" mass="39913" checksum="C33E6FC7FC01F866" modified="2020-06-17" version="1">MAANANSSADKPVKVRDVITSFRPTRRFRPDDPKTAVTSMDFDDSGELLLLARDDETLQIYNCREGKHAKEAKSHKYGVHLARFTHASSAVIYASTKVDDGIRYLSTHDNNYIRYFRGHTARVTSLALSPSSDQFLSAAADNTMRLWDLRSATAQGQLRLEGPYLCTYDPSATVIAVASPVTQSVLLYDIRNYDKPPFATFDLGPLEHRFLPGHQHRSWSTLAFSNDGKSLLLGTIGAGHFLLDAFDGALKHFATRATGRTASRSAAPSTGRRAAGDIGPGNVPYGDGDVAFSPDGQYLLGGAGEHNVLVWDVHAAQEPNKVLQPMAELPGLGRASVVGYNPKFHFFCSADRNLMMWLPDQELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNB7</accession>
    <name>A0A6A6NNB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aprataxin C2HE/C2H2/C2HC zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNB7"/>
    <dbReference type="OrthoDB" id="3512845at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033699">
        <property type="term" value="F:DNA 5'-adenosine monophosphate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990165">
        <property type="term" value="F:single-strand break-containing DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000012">
        <property type="term" value="P:single strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032566">
        <property type="entry name" value="Znf-C2HE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF4">
        <property type="entry name" value="APRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16278">
        <property type="entry name" value="zf-C2HE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aprataxin C2HE/C2H2/C2HC zinc finger" evidence="1">
        <location>
            <begin position="28"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="89" mass="10579" checksum="E9AE0C497D4C483F" modified="2020-06-17" version="1">MANLHVHVLSPDRVSDALKSRKHYNSFSTPFFVPLADLPLAADDERRWPGKHGWLKAEMRCWRCGKKMEDGWRKMKGHLEEEFEEWKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNE8</accession>
    <name>A0A6A6NNE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative serine esterase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_404499</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNE8"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF65">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="5">
        <location>
            <begin position="10"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="452" mass="47407" checksum="1633CBCA8FA95A8D" modified="2020-06-17" version="1">MPMHPLTSPHRLWGNASHFDYMAAALRARFPADRLRILVATSNTGAFTYDGVERGAERVMREVESALREMMAGGEEEGVLSIVGYSLGGLVARYVVGLLEWKGWFEKVQPVNFTTFATPHLGVRTPLPGLHNHLWNVVGARTLSASGRQLFLTDRFRHTDRPLLSLLADPASVFVRGLARFARRAAYANIVNDTASVYYTTCIAGADPFADLAKVRLNYLRGYAPVLLDPAAPVAVPSPHDPRPAPAAPPVAAAAARRLALALALPLAALLFLLAAALQSARSALRIRRHDRGAAAWEWAGVPLAAAAAVDGVDGAFGGTGADDGGSESGSGADELDGEALLGGRGGEALLGGRGGEGAAAASLSASSSPPSSTSPQAPSPSASGLAFPPLALSPAQRAMLRTLDALGWARFPVHIQRSAHSHAAIIVRARGRKGFEEGEVVVGHWVEGFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNH1</accession>
    <name>A0A6A6NNH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3 11">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_375246</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3 11"/>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNH1"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043647">
        <property type="term" value="P:inositol phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="37303" checksum="9FC68D672DE3EE49" modified="2020-06-17" version="1">MPYETELRTALLALQRASLLTRRVALTTLSSVTKSDRSPVTVGDFGAQALVISALRHAFPDDAIVAEEDAAALRDNEALRGKVWDYVQGAGLSDEGAESSIGGPLKSERDMLDAIDGGASEGFASAGSQGRRVWALDPIDGTKGFLRGGQYAIALALLVDAKPVLGVLACPNLPQDASAPIPTEHAHEKGEGEGYGVLVSAVAGQGTTVRVLGSGGVAEGKPTKMREVGEAQIGSAVFCESVESGHSSHDHHALITQKLGVTSSPVRMDSQAKYASLAMGLADVYLRLPVSASYQEKIWDHAAGEIVVKEAGGMVGDVQGRPLDWAQGRTLKENKGVVVAGKGVWDMVISAVKDVLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNT9</accession>
    <name>A0A6A6NNT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_130100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="7"/>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNT9"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF5">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="12">
        <location>
            <begin position="20"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="13">
        <location>
            <begin position="293"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="9">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2453376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="43609" checksum="8A1EDF211C722DC7" modified="2020-06-17" version="1">MANFIQKGAKNILQKGPNDVVFLSALRTPVTRARKGGLKDAYDHEMLAAVLKATLARNPNLDPALIQDIQIGTVLSELGGSKAGRMAALHVGYPTNVAFQTINRACSSGLAAVTSVAHSIATGAVDIGIGGGMESMTRNYGTHAIPTQLWDELRNSPIKEARDCIMGMGMTSENVAERYGVSRQDQDVFAAHSHVKAAKAWDSGLFDDEVIPVTTRIRPNPEIPEQVEEVTVRKDDGIRPKSTPETLAGMKPAFKPNGASTAGNSSQISDGAAAALMMRRSTVHALGLSSSIVGKWAGTQVVGTPPDEMGVGPAVAIPKLLDYTGVRKEEIGIWEINEAFASQALYCLRKLKIEESKVNPNGGAIALGHPLGATGARMLSTLLSEMGRQGQDLGVVSMCVGTGMGMASLIVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNZ1</accession>
    <name>A0A6A6NNZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_356091</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNZ1"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="234"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="534"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="652"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="609"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="702" mass="78926" checksum="6F7448BBD8AC5573" modified="2020-06-17" version="1">MLDPNVFAVLTPCDEKNRARTAFSLPENADRFHKAVGGVAEEPTIDSRQSTPSLLSPSEETGGEDEDATDRIILTFDKPSKDPLKGWQFGTNKASSDVLLGHRGTRGISGRQFNIAVDERLWVFLHDYHSSHGTAVSYNHKNKDEVRKKETWILSRGPGKSTPWKVVMIHVGHMAIKIEFPNQQAGKPEYMENLRAFFNRSQSALPLLEKIDFESYPSTATPSQPQTPRHQAIYLDDEMIGHGEFGEVRRVIKARDGLYYAAKTFTPLFKDSDGDQKRKRDEEQWRDQIRNEIDIMRNNPHPNVMPVVEFRFTPNPFLVMPYYRDGHLTRHLRHLNEKQYVSALRQILLGLRHLHERGIIHRDLKPENLLVDIDKDTKEITIVIADFGFSKDATPTNDLLKTFCGSLLYAAPDIFFGRSDGYGAKVDIWSAGVIVFGMYGLPEAPPSPWKKEARQQAVALENWISTWTQSLLDKLDDANENDDKVVNMLLHMIDPDPEKRYSAHECLQMGCRNGLFRATRDGRIVDADADDMADNTMHAHPTLTRDGEETPPPQSPRLPETGADNTTFIARNLRGGVRCSGEDSVNSPSDMKDSGRRTRRRRTSGTSSWSLTIGPSNSDSDGGFSMADSEPRLNEGPMTGLFIRRDRFTGSLVSRQPHGDESGGQLEEEQDGGAVTPRPEPVIAATAHLASFERRLFESLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPE8</accession>
    <name>A0A6A6NPE8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_367059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPE8"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF177">
        <property type="entry name" value="PROTEIN YOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="399" mass="43241" checksum="41E00CADBA18A960" modified="2020-06-17" version="1">MFDIVPNFLTLALTLVLPTFAAHRALRTSDPALLAPWLIYFLLISVLHAAESFVSPFLFFVPFYAWFRLLAHIYLLLPGGSDGTSFDPSDPNAARGGSWGATYIYYEHLAPVLTAHENQVDALVSNAHDTAKTYIRLGINEVLNVIRVRIFGMEPIAAPPPSPPPGRGGSYAQTLLSRFSIPAARDGLAAGQIGDWYGVVSGALSGATGAAARYGNTSGDAASSGGSGATGWWTSSAAADRAADELSRSGTLVPPSVGEGPERAGYVAAQVDRLRVLLQAFEREAATMDDGTVGRTPPPSGLSKSRSELEFDTLEGDEDLLAYGSTGGVEQRPRRSKRESSGGWMPWNWNAPPDEIPTRSRADYRDRGYRDREYYDRDYDDREIDRRERARASGFDIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU2</accession>
    <name>A0A6A6NPU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU2"/>
    <dbReference type="OrthoDB" id="2402960at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="517" mass="52654" checksum="58FAD9CB25B66C20" modified="2020-06-17" version="1">MDPPPPADVSGADAFAQTRSPDDLFFDDDFTPVADPTPVALDEGPPAAVQAAATGAASSSSSPAPPPNAPTGPAASLTPATDPQPPTGAPTGPREKRGPSPSYFAPRGGAPPIQRGGGAHRGGAGAGGERGRGGRRGARGGGRGGAVLQEDGNRSHNRQRDQPRESQPQKDEGSKAAGEEKVETETDEKGEAGVMAAVEGNANGESASEDAAAKAERAGARAAPAVKGDRSGTGGVRKTKLTPTELSARLAAAAERNAHLVAAHERAAHDAAAFEAREAQAAREASVRAEQQRRRNDEKAKVERQNRQQLAAERERNRARKMQAAEGREWDREKKEGGFEGFGGERGGRARRGAHGGVVGPKGEEDAAAAASPVEEEGDQHGAAGRAGRCGRGRGGRGGGRGGRGGHGGHGGHADRHNGRPGQQQPQAPPSAADFPELPAASKKADPAAADARPVVLEFPNRKKDGAANGAKEGEAAEEAKGARPPAKKQESWGLGVQSPTADGGTKSWADQVEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ18</accession>
    <name>A0A6A6NQ18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_355762</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ18"/>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000171">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="415" mass="45714" checksum="0A2A86F4163AA2BA" modified="2020-06-17" version="1">MLTGALFWGLGADIIGRKYAFNLSLLICSIFAIVAGSSPNWIVLGLFVCLSAFGGGGNLVLDTAVFLEYLPSQRQWMVTMMAAWWGIGQLIAGLFAWGFMPNYSCESAETCTYDNNKGWRYVWFASGSLVFVMSILRVTVIRLTETPKYLMGEGKDAEVVATLRKIADKHGRTCSLTIEALEACGVTGTAQERRASVTAHAKKRFSGGEVWTHLKGLYATRRMALSTSLIWFSWLLIGLAYPLYNVFLPSYLASRGAEFGQDSPYITWRNYTLVNFCGIWGPLLAGWMCRQKWFWGRRGTMIIGALLSMTFFFAYTAVRSASQNLGFTCTVNFCLNIYYGTLYAYTPEVLPSAHRGTGNGIAIGLNRIMGIMSAVIATVADTTTPVPIYICAALYALMAIVAALFPFEPFGSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQD9</accession>
    <name>A0A6A6NQD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQD9"/>
    <dbReference type="OrthoDB" id="3945642at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="795" mass="90018" checksum="DB0589107D4A5D5C" modified="2020-06-17" version="1">MAMAAPMPPPPPPPGPFPPPPPPPPPPPANVPTNHAPEPALPGGSRTSTGSYMTRNAGPGAEMRPHIHPSAPPQQFQTEDFARDGGRRRPLGNQPSRTYQGWIYRKMKLRDLPPGQRSSWSRTLRDKLPQSSDDLLKAVKSHKQGVRLTGYQEYLQLKNQNMKAIIEHLLQEYRAQERDSQAEWSIACIDTTEKPVGMFPYKGTETTELRVILERSIRSDTAPYIPGPLHNSGIAGEIVDLTELDRMREIAGIDKVPQSQPARMMNQPRQMTQPPPSNQFSAQNSQGRNQPNAPNQSEARQPPQIGPTNFPPPQPGLNPPPPPPQQSQSMQRAPDSRIGAMHPQMQGPGQPPNIPTGSKAPKKQGQLQQPSAAPPPPPPPPSPPQQRFSPKPSSQQLPAPNAKVKTENKKATPSIYASDDDMIDMTDESDTVLVKKKTRPMMSGGKGSGKEHVQQEVLQSDRRSSTPIFRKKSIKEIKKARERSRSSSPWKVSTRTKSTKKVEEQYRPDLPGEHDSHRGRRYRRHLDNSDEDSYGSRRHRRHYSDSSELSDPSDSGTASTSSQGDYHDSRRMSRQRSYRYRSSLPVKEHTKPPAYADSHRRRSLSRRRSSSRRSSFSDSDGADSPISEPLSRNSSDDRRRRMQLDRRNPPRRSVTHIPAPNALLPMVPDAPAVSLDDYLRRLRIDDWQQDGLQRLQLQEERRRLEEEEMRMRNRRIIEQEQALRWRELALKREEINRRDHEYRRQPFAAPEAAGRYPLRSSLRQPQGTYAEPRAYAEPRAYAEPFNRDGSWGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQS4</accession>
    <name>A0A6A6NQS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dynein light intermediate chain-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_354274</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQS4"/>
    <dbReference type="OrthoDB" id="27603at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008467">
        <property type="entry name" value="Dynein1_light_intermed_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022780">
        <property type="entry name" value="Dynein_light_int_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688:SF0">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05783">
        <property type="entry name" value="DLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="559"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="628"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="690" mass="72611" checksum="F29430769C30423F" modified="2020-06-17" version="1">MRATGRRVSTYMSTDNDRPRSSDGNKRDIWSSMLDGASSGRRLPAKNVLVLGGTPESQREFLDTLGTTRRGQQAPTADRNRKPPIANQFALGYTYQDVMDADHEDVLARLSLYLLTTPHPNFARLLSPLLTPKALPHTLIVILLDWTHPWLWVRQLRAWIRVLRAVLLGLPDEAKDALEANIDRWRAGRTNAHPSAASAADISTPDRPGTPATTTPTASADPRELDAAARVALPLGPGEYDEPLGMPLLVVAQRADRVAALERERGWGDDEFDFVLQYLRTLLLKHGGGLAYVLPASSGALPPGGSVATDGGAGGGASGAVGGVESPAATLQALVHSALGLPPGAGSSVPPVGARNRNSASGVAPGQRLKHNVVDRERILVPPHWDSWGKIRVLREGFDVEGVSQAWSSDIRVPEWLARRVEGLSAAAGSISNGTATMNGAAMAAEDGVASPGNGDMAVGAAQTGTVEEDAEDDIADNEELIDDPTEPPNSAVAMYEDTIKTPPSSATNVTGVLAVASSSSMEALARARKPRPRIDTPATDNQSFLAQQLEVLERLKAEDEAERRARESRKTGATAGLGAGPEGSGFAVSSGAVGSGVVEEHIGPVQFNVGGIHVDAEEVVKRLKDREATRAGQAGQNAAPGSERDVSGGSFSPTNAVFSSQDDKAENEALSVFFKGLANRSVTGSPRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQZ1</accession>
    <name>A0A6A6NQZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_120024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQZ1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="19081" checksum="23FA3D5F1FAA3D9B" modified="2020-06-17" version="1">MELTDNDLSSGWLSDAGSGNFHAADRLLALPRCFCFARRRHGSACAYALERLRCQQQQLASNNSNREAEVGDGAVSRPTSQAARRGGVLLYFNAFTLAAKFQPVRNQGKPSQCRSVPEHCNAPSSRQTTNRPKPIQWTHFATSHDTRGTPDQGTGRTRQVGAADVVSPAPAPALSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR23</accession>
    <name>A0A6A6NR23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_353833</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR23"/>
    <dbReference type="OrthoDB" id="5363290at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42083">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42083:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17907" checksum="D17C06E1A5FB79B9" modified="2020-06-17" version="1">MFNLSEQSKQGGAIGLIFRTLVRFLQLVLALTVCGLYGTDLNAARKADKYADSKWVYAVVVAGMSAVTCLVYLTPFIKAFYAFAWDFVLWVLWLAAFGVFGKLYIGEDPEGNGGIERMKNAVWVDLVNMLLWFITFVYSTFVFFHHRKRSLHTGRAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR63</accession>
    <name>A0A6A6NR63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR63"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="72" mass="7572" checksum="4596A2B20BDFA138" modified="2020-06-17" version="1">MERESLRRSQVGDRLALPGLGGGSEAGDARSRRASSIGLPGPGEPEEQSPQNQNGRLGPRGLRKMSGTKGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRJ9</accession>
    <name>A0A6A6NRJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_416867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRJ9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="25678" checksum="860331425D16A67E" modified="2020-06-17" version="1" fragment="single">PVPRFRGASSSSFGFLPARQDEKGPCSFRERERESLPASAPWSSSSAGTRRLFPPRRVSGAFPLRGRVVCALRGTEPGRKRRGFLPRLFAPASAPFALGIFGYPEPQTPSGGVLKVPFPWARPKPAPFRPPGRPGDPEQQKPRSTPAGNHPAYRSHLETDQQRDRCGPAPEPVSSASPPQLPAPLYPLLTQPAALVPAHSSPSSNPAAGRRPKHVPIVIPHYDPVVAPETDPCHTTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRR9</accession>
    <name>A0A6A6NRR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRR9"/>
    <dbReference type="OrthoDB" id="3942368at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="744" mass="80291" checksum="308E6E158B90D830" modified="2020-06-17" version="1">MTESVFTIDTIEATPDCSTLSWNDPVVKTPQGQRVTIWDSAKENEFKNAIDGSTHPATFLLPNANPPTIPIHIHGSISLEFEPDGNTKGLVTASLGSLDLFRAAVIVGSQDQVVVIDKVELVNAYTRLPTRSSGDFQFRLELYHPKAKNPILAKRTPRLEISFALGPCPSSETSPNNRVRADFGGRYPVILLRLFFPSLSEALSIAGIHPPVAPETWYIKRAVDTIWKFGTTPDVNKSVRIPRKIHYDNVNGAPSYGVSPKGVGTFQLSRWAKAQFDQCNCQDLAAIVQLACNVLVSGPNSIEVVDSRWIEHRPHGFLNPGTLFGWPEYPRCNNPTWKNKDAVWKFAECPVAKVDTATGYPLEGFAQHSWVEIVLPGDTGPGTVLDATLGLLSRGGQPETGSTPRGAYLNTSLIQTTVNPNPLGNGTTKTTANPNGDCLQTPESGPDIGLKAISLTKILSPISRVALKSMEDIATDTERPLDPTFDGTNPEEPPRNFVCADLTVPKLHELAEPVLGQTTIGVSEYLVGTTGAQVLAGLDVAAEPDMEAPPTSVFIEVTAYLDLLDAAMAVTDRLNSSSTGRAPYKKSPENDRVGDMSYVSPIEVFFARSNVFVRVFGNGLAPGVDYAPKFLAVGRALDAHMSQRLVGRPELPMPSPKLGQGPPETVPVGGIFTLAITEDSAATTLVEKVAHVEDSSVLQWLGPKFDDGRFEFLATKKGITKVVLVVAHESHLLPGTEEVSVTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS50</accession>
    <name>A0A6A6NS50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS50"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="87" mass="9383" checksum="83B703444C278648" modified="2020-06-17" version="1">MRQNWGGTRKGPQNACLLLPFACLFFSFAFLSPFLGRGGFKGRAHEARRAGRPDSFKPGDGTVWPVPGDPHLTEFAGPRGGVGQPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS89</accession>
    <name>A0A6A6NS89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS89"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="560" mass="62160" checksum="DA2EA2F90028810D" modified="2020-06-17" version="1">MSLVSESDGPWEEAFEPDGPQEQIFDTQSPVPRVLLPPETCQPGIYGLSDEATERIRMEGRLFAKAIVRLPWAYDPPVDDRRQPEDMTEPETDAIVQWASELNPEDSIQSDTEQGQITEKEDDLEPFPDFHNIDWVEADPRVEGITDIPGDMAEGYRTGTTSVDMEAQEDPGEPANVETGSPPNGEKTITLDPQQKTLLELLKGTAKEPSPTKQSERAPGDAELHVSAKNVHAEAEIQDDLVETTAKEIQPDPKAEEFGAEASKIRPRALKLPLETIFEEPPRIEQDEASPRDVDIHLPTEVPKGEGKNVEIQDQEVECELAKSEESRKSRAVALHPGSRVKTPFSLDDIEAVKAAEKDSAYGGDDESDNAQSPLAQVENREVSSMHMKSVVHTHSHADKSRGKGHEHAVGFSCTQSKVQEEASASPGSNLPQPHYTKEHVSHVTKSEPESKSAELAKVDIREQLEQPESTVEDKHLGMQSRDFAEKFAKDAPEDAISNIGLKNEDSTAPTQKEAEQDERTYFRPVIVTSEDKFSVYNIRVQRRVKRVEKPETKGAQRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSM4</accession>
    <name>A0A6A6NSM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_365831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSM4"/>
    <dbReference type="OrthoDB" id="5584477at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="395"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="780" mass="89269" checksum="D2426124D04C4CFB" modified="2020-06-17" version="1">MLLSVWHPAFLQNTRPRDAAPKLRLNENKPVLTSFSLERYCREAEQSFILAFGPSSDVAGDQEHDFQDVISRLILALTGTRAAFHLRSKTRSEDVASELVTLFRRIRNDDFTYDRYRPLVKLVIDRKPDVEIWSAVFDLITTLSRATPPASVPAGFDDTPITHTSASQQGAEQTRKLVEERLFEEIGRCTYPSVEGFVEKHFEGKDWTPRALKIYKKIKPRYKDGRWTDFPDPLVQDGVVDWWFRFQDEFLSGERHRYYKTSSPKELTRAEVRRQIDLFVKRNEGPSTNTVHDLKDVKIIGELKESSKDKKGTLLHISRYIRDIFLCQPICRYIPAFTLCGREMQLWIFDRSGPYGPKRFDIHDEPERFIQVITGYLMMNDEELGLDTFVQEDPAGRFITLERGDESHIKLRLELSAFVHQRAIVCRGTSCFLAKTLDSESHNCVAKFSWTSDRRKQEADLLRLAYQRGVQGVANLVGHHQIASIADMRSGLTFGKLYPFRGPPSAASSSQSFPQSLQPSLASRSFSDLQDLSIARKPSKRSRSNNSYDHRTFRCLVTSPAGRSMRTYKSPLELLVVLRDAIRAHKSLYLTGNILHRDISENNIIITDPEKDGFQGVLIDLDLAKELRTGRSGARCRTGTMEFMAIEVLLGISHTYRHDLESFFYVLLWLCARRGWEKSNSATGQSTSQLRAWYTGNYEDIANAKLGHTSKTESGGLLFILREFPPEFDCVKPLCWELRAILFPYRDGLFTGTPKDPEVLYEPILRAFDSAVDDIKANEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSY2</accession>
    <name>A0A6A6NSY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_373780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC12A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2020542at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055064">
        <property type="term" value="P:chloride ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055075">
        <property type="term" value="P:potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000013">
        <property type="entry name" value="Solute carrier family 12 member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="637"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="673"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="700"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="276"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="10">
        <location>
            <begin position="764"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="861"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="992"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1162"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1224"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1299"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1346"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1724"/>
            <end position="1745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="871"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="998"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1224"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1305"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1315"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1346"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1395"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1440"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1458"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1540"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1567"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1599"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1676"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1729"/>
            <end position="1745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1801" mass="189349" checksum="E3499BE8D5B64E58" modified="2020-06-17" version="1">MTDPPAAARPLLPRVHSAFATRSAIDAGDRLSRRASHAPASTASTASADERPEPAPAASAVAPAAPEHELRRPGTGARIGSPDASGGASGGLLLRRGAGAAYDGAAEGWGGGAGRRGGAGGGGEGGGFLGGGGGAGTLGWRSWWWRSWRGRDAGRGRDGEAEEGDGERAPLLLGRRDEEEGAVGLGGLRRRAGPAQLRRQHHHHHHHHHHLQHPHHGYGAAGVAADEDAKASAVAKGSVPGGAAGAAAAAARLKKKTGALPRPVGGSSKLGTFAGVFVPTTLNVLSILMFLRFGFILGQTGVVGMMGMLIVCFAIDLVTTLSISAIATNGTVRGGGAYYLISRSLGPEFGGSIGIVFYLGFVFNTGMNAVGLIDCLTENFGSETGNWANWLPEEYWWRYLWSTVVLLLCTAICLAGSGLFARASNGLLAMLLVATFSIPLSTFVVRPFTSDRLGIEYTGLSFATLRDNLLPHFTKNAAGSQLKGRENFQDVFGILFPACSGIFAGASMSGDLKHPSKAIPKGTLYGLGLTFAAYTIVIFSMAASISRTSFYHNTNVIQDVNMSGAIILLGEFATSFFSSLMGVIGSAKLLQALARDDLLPGLHIFGQGTAKADEPTFAIIFTYIAAQLTMLADINQIASFVTMTYLMTFLVTNLACFLLKISSAPNFRPSFHYFSWGTALTGALASGATMFFVDGFYASGCIGILIVLFLLIHYTTPPKSWGDVSQSLIYHQVRKYLLRLRQEHVKYWRPQILLFVNDPRRSYKLIQFCNSLKKGALFILGHVIVNQDFGASVPEARRQQHTWTKYIDFSKIKGFVNIVISPGVEWGARNIVLTAGLGGMRPNIVVLGFYNLPELRSARPSLLPRTRGSAPPSTLSSPVAAQHPQLKSQHSLEASVTSLEGADQKEAPSGSKPSRRRGREDAKLKGQLPTDANKAESSVSVQSYMTVLEDLLLRLQVNVAIAKGFQDLEMPAPKPKTRDNLRTLLRRYLSLGRSKSNDEEEEEEADEEDVPPHQQKKYIDLWPIQMAAEIAPERASPTVGASAGTHHRNVLTTNFDTYTLILQLGCILTTVPSWKRTYSLRVAVFVEYEADVAEERGRVASLLTNLRIQAEVLVFWLASGELKTYEVIINGRSGGEFAEAERVVDEALSEDDWWAQVQAFRRMGAPPPPDGGPEGAGIEGAQHEQSGQRPASGRPRASTAPAKDFAASLLSAAENWPPAAYQLGGGGSGGGGGHHGAARGSIAGGEIGAGSPSSRRRFAGLRKMLGKSAIGGRGTQQRRRSVRALERWGVNLGMRTHRLDPALIGRGGDSGSEGGETSSSSEGSVSSGEVSEVELLDDEDDLAASENDIDEDEAGGAEARAGDSVKRSKSMGTSSRPAWLRHAFALRKSQEQQETAPPTTTTATTTTKTAISHGVASDTVLPGNAREPALQPRISLRTASPEPKQSQSQPQLSPPLPKQQQQQQQRVQQQYHAQASASSSQGPSAPASGTATPSRPPFPRQMSQPKFTSKPVPRTHVAADDGPGPSIMFTDQPSPEERAGAAQEGTQGQQLGQQRGPQRSIYHRRGGGSASGSGGGSGGGGGESGSGFAGSRDVGGSSMPASAQTDTGRASEAAAPERRRGLPGEDGGQGAHAASGVAAPDHPSAPPSAPGSPVGQPGEAQPPERAGAGESAGATSPPPPQPPSPTATAAPASGWPLPAALPLSFNDLPCRAQHVILNELMQAHSGRGEPNGGGSGGGGAGGLGEAGRTAVVFTTLPAPAEGTSRSEEESVRYLSDLETLCVGLPPVLLVHSNSMTVTMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT61</accession>
    <name>A0A6A6NT61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_290227</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2454990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT61"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000044">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="31"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="682"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="604"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="619"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="682"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="700"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="788" mass="86361" checksum="C53B28A671A6208B" modified="2020-06-17" version="1">MFHFGYVTSNYANSLYVRPPQGKVAELRAELQAGGKKDKNHSSKKIALKKIVANMTMSNNDMVGLFADIVACMHIPSLEIKKMCFLYLVNYARIKPDVALKALPIIVQDMDDSNPLVRALALRTMSYINVREFVEATVPPLKRLLKDSDPYVRKTAAFCVAKLYDHDKRMVESSDLIDLLNGMLRDENPTVVSSALAALMDIWERSDSIKLTIDYPSASKIVQILPDCSEWGQTYILEAMMNYVPHDTGEAALLAERIAPRLSHNNSSVVLTAIRVIMYLMNYVADQKVIASLCNKLSPPLVTLLSKGPEIQYLALRNALLILQRYPEVLRNDVRVFFCKYNDPIYVKVTKLELIFMLATERNINEVLTELREYATEIDVDFARKSVRAIGKLAIKIEPAARLCINTLLDLVATKVSYIVQEATVVIRNIFRKYPNQYESIISTLCTHLDSLDEPEAKAAMIWIIGQYADRIDNADALLEDFLFSFAEEPTEVQLALLTATVKLFIQRPTKSQHLVPKVLKWATEETDNPDLRDRGYMYWRLLSSDPATAKQVVMGPKPAISAESERLDPSTLEEMCLVIGTLATVYLKPVHIVFRTARPRRLHSSPALQRHRLPTAEAAREAVAERDRLKKEAEEEEAMKLPLRPPASGGLPGSNMASAVDAADLYFSGLGNGGSAATNNNANANANNSNGNANGGGTPTSATAPVAGNPNPNPNSNAMPGNPGTVPLGYGAGGMGGPGSAAMMMDGLGGGVVGSPADGGSGGQNLYVVNQNQQQAYHPANGDLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTG6</accession>
    <name>A0A6A6NTG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_351792</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTG6"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="145" mass="15843" checksum="1053AB9C3D227959" modified="2020-06-17" version="1">MAAAIKAVNAKIRSNKVLDYFCSTHFWGPASNFGIPIAAVMDTQKDPEIVSGPMTVALTAYSAIFARYAMAVTPKNYLLFGCHVINFSAQVTQGYRYLNYWKFGGREKALEAKEQAKGPTEKAAEVAKDASEKVKDAGEKILGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI1</accession>
    <name>A0A6A6NTI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_381104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI1"/>
    <dbReference type="OrthoDB" id="438641at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="802" mass="88626" checksum="BCD87DCFE8FB50B2" modified="2020-06-17" version="1">MDDAHIAANGIAIANSELAAGRVMSARDIYTEILIKDSPGHPGAFLNRALCYLALDYPALAVFDCHRALIGAHMAARKEGRALKVQLEILDKYMNKLVDSGDDDIASWTHAPNCYVNSQDVEFLSCPLASLVLRSRLAIIMPPPQTEYEKAFGIKNHPKTQKVHIINTAIDRAYYRLAYSLWKCGGGAISSALDVIAAARDLSGNHFLGDDKVCLDKLELHIYDYIERCMHDEREWVRKTNEDDRKDPRDPVAKVGAFSKLLFSRYTTIRRELYPWDRYSMNEITLGVQCPLDPSAKLGFALIPEVGKAPKAVLYAKDDITDPFIFEVTRDFVVSTSDTEGRKSTPGMAGSAENDNNSASNWTNDNSAILFDLRHPPVSGERLALCGTGLDEYCRSAYRVIDPVYMPSLNGDDGVDQLKNGLGIPLKPVQTLQKLMLAKVLANFIVQARGGRIGFNDPWIRILDGDLGRVADLPVPGPEDPYERASARIARTFYGVPASRDAPPLFKGLFPRCEYAEVLDRSRPADSIVSLRQISPMQWEKDLPERNSRLGFSYQHSVIDTLNMLHCLGGYKAVFNLSQYDGWMLLNLQAKIETGMRVTKGARFEKFFDERRFQTDHGPAAAFEEYSGRPEQDPDVPPREPEVPVEDPSGSPPPSPVDGPVWIGSLDPIAHTVRPAAAIASLAAPNVELYESDARVRCFARGWDRLARLDRDPVELFGHVNGVLGPEPMDVDGEDAEARRLLEEVGGALRGGVPPPAPARGEGLRWPMEDGGGDVQGLVIRAGTVLVRGEAVQPAEEWQDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTT1</accession>
    <name>A0A6A6NTT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_325072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTT1"/>
    <dbReference type="OrthoDB" id="2529286at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34582" checksum="4F755272EB9F96E3" modified="2020-06-17" version="1">MEFAISAALGDEVSDPSEEAFWLLSQSIPSQDLGFVDPRAAEISFSVADRDLTIQQSPALLSSDRKQGTTGAVVWKVTPLVAEWAASPERLLFRLGALGPAKTVLELGCGVAGVLGLALAPSVGKYVATDQNYVLRLLRENIALNNGDEEASTTTTNKHQHRHGKGNTKKEAGHHREWKPSRGTGNFGTIEVIPLDWETDDVSFFTDIGCSSSKGVDVLIACDCIYNESLVEPFVTTCRDICRLRSNQVHDNESSEEPTLCVVASQIRSWEVMDAFLVEFHRWFRLWRVPDRQLPESLQENSGFSVHVGILRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTU2</accession>
    <name>A0A6A6NTU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_80402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTU2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="16696" checksum="50FCF12B79475B96" modified="2020-06-17" version="1">MCPTGKTTTYRCTYCVGPRRRSLLTYSNARPAAVRPTLTLPSALPRGHGMQPLVQPASPDPNAWEATAQTRKRARTTAAGEGRCRSWHAVLRRQGPLGGGGVARCDTVVGGRRRLPVSGGRRPERAPVPEGAPAIFGGLSALRRRHWSVDRRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUC6</accession>
    <name>A0A6A6NUC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_79063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUC6"/>
    <dbReference type="OrthoDB" id="15433at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="22885" checksum="CA024B351BA84130" modified="2020-06-17" version="1">MPLRPFPWPLRVGTDICYVPRIHQLITRGTQGRQQANLNPERFSRFLRKLFGNHEIRAFQARWPNADEALQNGRTYEMAQYIAARWAAKEAVIKANAPRKLGFHDIVIAKNDFREPIAIVLDKPWTRGLLCKPVNDIEERDSSHFIQCSDSDRPESGSENARKNHDRLNLESEGLHGQIARLSISHDGEYVTAACLAACEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUF3</accession>
    <name>A0A6A6NUF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="14">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_365693</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="14"/>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUF3"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="381"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2455062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="564" mass="63728" checksum="8D2E08A0CBD20DC5" modified="2020-06-17" version="1">MRGSFRRTSNPTTPYKLLAAALVIAFYFVTMLLRHSSQPARSPRPRDRGPAIQLQKWENDTGGPDTPKVTRVKDAMVHTFRNYRAAAWGHDDVLPVSGGYGDSRNGWGAFIVDSASTLALMGLWHELKLAIEHIVRVDFTITEDLVDPFETTIRYLGGLLSLVDLIDSQVVPPSVVSPGDRDKILAQAVALANKLGPAYDSPTGLAWPRVDFALNQGVPDPPEVYLKDPSKPRYEHPVINAARAGSSILENRALSRLSGREIYYQNATKSWAPLVWNRYLEEYPGLVDTPIDIVTGDAVSHQHHWDAGHDSYYEYLLKAAVLAPGDRYSDRYKSRWLAAARSFHKQLTSRSTPTETHKTQHLFMGKYHTGNLLNVQSHLACWAPGSFLLGGAYLQNKTMLNLGRALLEGCHHTYQSTTTGIGPESFSWIPYTNFPEIIYEPRADRSKAELAAHGFWAADPRFLLRPEYVEAVFYGWRITGEQRYRDWAWEAFEAMEKHCRTEHGYAAIADVFAEEGRVVQLDEQESFWSAETLKYLWLTFADVRVGSLDDWVYTTEGHPLRRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV44</accession>
    <name>A0A6A6NV44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_349909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV44"/>
    <dbReference type="OrthoDB" id="10010920at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.120:FF:000004">
        <property type="entry name" value="Ion channel, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="entry name" value="Large-conductance mechanosensitive channel, MscL, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266:SF2">
        <property type="entry name" value="LARGE-CONDUCTANCE MECHANOSENSITIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="MECHANOSENSITIVE CHANNEL MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="Gated mechanosensitive channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="19522" checksum="D31A292F6FFD2C0D" modified="2020-06-17" version="1">MDDNREALLRAGERVTRRAKWAWEGFTEFALQDNVLEVAVGLIIANAFNAIVSSLTTDLILPVFALLPFVNRNLEEKFAVLRSGHHEPADGYNTAKQAREDAATVLAWGSFLDKVVRFLVIATSLYLIAQIYDLISSDSIIKTTVKCRFCRKRINEKALRCVNCTSWQDGRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVQ7</accession>
    <name>A0A6A6NVQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_61211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVQ7"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="179"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="27957" checksum="77CB2667EF56E9A4" modified="2020-06-17" version="1">MGTAAFLNSQSPDVQNTDAGAAQSRIDPAGATAFDLSYGLDQRGPSQEVFLDDFATDDSLMTPITPNETFFQEPTTYFQQQPSVSQPTSWRSPIDSNASSESVAVSPSYTEDMPKSRQKARSQGTSTSVTSQSSAAGAGSATGLSSVTGSVTGSEDAPKRGRGRPKLQPSTGDGPSKPGERVPHTQVERKYRETLNKEMERLREALPTLPFLPQEDGASGPKPKKATILATAVNYIKFLENEYERLDKEIQELKRDGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVU2</accession>
    <name>A0A6A6NVU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mtf2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_365586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVU2"/>
    <dbReference type="OrthoDB" id="2444174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043837">
        <property type="entry name" value="Mtf2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040009">
        <property type="entry name" value="Mtf2/C5D6.12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468:SF1">
        <property type="entry name" value="MTF2-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19189">
        <property type="entry name" value="Mtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mtf2-like C-terminal" evidence="2">
        <location>
            <begin position="201"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="457" mass="51165" checksum="A4883DE15F02E910" modified="2020-06-17" version="1">MRKHQRHRPFKRPLLDEDPVPFEGISEPTHISTAPRPPASRDSAFGALIDDGADKSTITNQERAAFQRLFDWAIARPDRAAAPAQPKPKPKPQQRRAPRGKTAEHDMSEIMAEAFSGEDGGGGPAPSARTRRVRERAGRDAPMRSFPDSLQRMATRAMERMRARGAEERPEGPEAPPRGPATAAADVEAADPMKEMREAEYARVERLLDAAPTDAHLWLVLEREVFSRIRRLDLDGEAARQERRKEKERRRRERRRRKKQGEAVEATDEAGREEAAPASPAPAAGGDADSQLLHDLALIGPSYPTLLLLAIRLLRQRFPSSSLPLSVLPTIKLLGRPAYMLGVSTLLYNEVLAVTWMRRADYAAVDELLRDMDGAGLEFDTRTLGLLDLVRRWDRDVVNGRFGDGLRVAFTMDGPRTAAAKVKSWEEVARKRLEEEALRRASEREREQLGGHLAMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW26</accession>
    <name>A0A6A6NW26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phox homologous domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_288944</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW26"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097576">
        <property type="term" value="P:vacuole fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15858">
        <property type="entry name" value="SNARE_VAM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000058">
        <property type="entry name" value="VAM7p Vacuolar SNARE protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="8">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="322"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="385" mass="41347" checksum="ACCDAB55DB51A3EA" modified="2020-06-17" version="1">MASPPPDDLTITIPSTHTAHPPDDSKPYTVYDVHVTTSLRTTVLRKRYSDFAALHASLLSATDNAAPPAPLPQKSWFPRSTVNNPSLTEARRQGLEAYMQAVASARDARWRSTRAWRAFLDLNEEPARRASKGAARLGSAAGAPANPSSPADWLDAHRDLKACLHDARAQLARREQAPAPAAQHDAGASAKKSLVRAGQLIHALEAGLDRMAAGGGGDGWPADKLGDGEVRRRRDMIGAAKKERDGLESLLGSMAAKTAKGAAAESSRSGSATPSEAGGGKEMLFKGGGGGGGRGRVLGAPPPKETERTRELDNEGVLQLQRQIMQEQDEDVFDLAKAVRRMKDMGIQINDELEAQTQMLDLLDQDVDRVGGKIRIAKKRTREIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW62</accession>
    <name>A0A6A6NW62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_395677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW62"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="276" mass="30000" checksum="638420615A73FA78" modified="2020-06-17" version="1">MLRHKNQSSARPQSFYLLNLHLRIPTTHPVSSNQNSPSKPHLILKLDNFPTAEMIFAIIIPSTAVGAISALLALLSFQSIVRAKQARSTHVAAVTTVGASSKRPLPLPPPTLPPTPPVTSNPATWDIDSPGLSPRVRFTCANWWEWAGAPFCTDPTGRRAMRRDNPPPPLELDTTRIGLSHFALPEAQAIRLSPGHGAMWVSENSPHPPSAVREFIFTGAWFARHGLSPLSPDILRGAAGPCKDRKKGAKEEKKTGATWEWSGAKEPAQFDGIFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWB7</accession>
    <name>A0A6A6NWB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_348604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWB7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17807" checksum="B1DF5ECA84FA9443" modified="2020-06-17" version="1">MRVITADGVALVAMELAESMMQPEPECGRGSAAVGTCETRRRRPQKRKAGSRNPSRPPFLAELQHRAFYKPRSAGNWLVGTCRTDSAPRPRARRARLAPLQRELSFRERLWRIAALQTRLTPSGPRPSRTVRSGTAGSGPDSRAASVFCHGYLIQLRRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWM0</accession>
    <name>A0A6A6NWM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_394645</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000010">
        <property type="entry name" value="Chitin synthase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="781"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="817"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1078"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1475"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1502"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1530"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="13">
        <location>
            <begin position="1770"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="349"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1673"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1688"/>
            <end position="1706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1828" mass="201570" checksum="9F0C958CE4B01A10" modified="2020-06-17" version="1">MAYSNRMSSYSHMSGHSAAPRGPSANPAASQQLSTTTLLNALHTSFMNGSPYFLEASTSVVVNTWLTAAENAGPDGRDGGTVDVELGRKAWEHARRRAEDGCIVLGSLHESTPSLLTPFVSSLPLSIPTSFYTALSVIKAFTNCVTPFNPSFPRYSSLAATFNMDLAGTLTGATLALSTSGLDTSTGLLNIPSESGYRAFDVFYWLVTSSASPAEREYLGLQHPSAYTLLKRSGTYLPPAYLATADDAAAAEDFRANLKALGIKGRAMRSLISTLAALLKLGDTLGFLVDEEVLDQVCEDVAGFLDLDPNVLRKKCDTQDREVFIAGVYEALLDWVIARANDAIRRDIRGGNRRAQTPMPLSASGSESGGGALTPLDDSDDDALDTPGDDGDSVSITVVDVPSPALGKAVALRNVFDDTEGINAEMKDDGVEVHAAGSSVLREMRDAVRAVEPDLGIMGNAAGREREYERDRREGVLEKAARELPAGGEYDGAGGAPFLRDVLLPVEGEGVVVGRHGRFELAHVLASSRVWFQLCAHPTDAGPADVARAAQSGAPVWSASAVSQQLRAWRAPEWANRRNKHLDFTADFDVDEFVQRYARLGCSEGRDGVESWCLERGWSNGEVVVGRERVWMREGQWWEAESMLDLKPADEAAAATAAAPESMMGGAYAVQNPSMSGFFGPSAGAGGGGGGPFNDAATMQGSRDNLLQRQQSSATLGGMGAKPRSLAPTQAHTLRSMGGGDYGLGTKGDVNNDVTYYGDLDPETGDNKIVTEQPISTARRVWVAVVWALTFWLPSPLLRYVGRMKRPDVRMAWREKLVLIMIIAFINALIVFYIVIFGKLLCPNKDKAWDEKEVSFHQGDNDFYVSHHGYVYDLSKFWKLQHSDTSVKTTTEMMQPFAGQNVDALIVPPLTKACRFLVDDELLELTSNTTVENPNAVHTQGRDQPVQASALRSLDWYEDKFLPRMDEYKKGDLVWTRDKVKDEGENLSHMWFILNEKIYDLTDYFHTLDVMNDIDRYHFFSTDVEDLVKENPGQDISEDWKNQLNVTTQLQSLNCLDNMFYRGIVDFRETPRCLVNNYILLAFTIILCTVILVKFLAALQLGSKRRPASQDKFVICQVPAYTEGEDQLRKGLDSLTALAYDNKRKLICVICDGMIVGGGNDRPTPKIVLDVLGVDPKIDPPALPFKSVGQGSEQLNYGKVYSGLYEYEGNVVPYIVVVKVGKESEQGKSKPGNRGKRDSQILLMNFLNRVHHRSAMNPLELEMFHQINNIIGVDPELYEYLLMVDADTMVKEDALNRLVASCANDAKIAGICGETSLENEERSWWTMIQVYEYYISHHLAKAFESLFGSVTCLPGCFCMYRLRTADKGRPLIISEKVINDYADCNVDTLHKKNLLSLGEDRYLTTLMTKYFPSMSYKFVPDAYAQTAAPEKWSILLSQRRRWINSTIHNLAELVFIKDLCGFCCFSMRFVVFIDLFGTITLPAVCIYLGYLIYLVATNQGQFPIFSIVIIAAVYGLQAIIFIIKRQWQHIGWMIIYMIAFPIYSFVLPIYSFWKQDDFSWGNTRIVVSEKGSKQIIAVDDSEDAGFDPRSIPLQRWDDYAAANNLPGRRGGPTSGGLGQVEKFAQHQPSGYYDDQYEMDDMQSVYSSVKPASTILTGFGNNGMGRNSPYGYRPPQSPAPFHGMAGRQSGYSALSSTPNLGGAAQQQDPHHYSRQMSFASPGFEQQPFGTSSATPPPGAMRGPSPLGHRGLSRPVSTVNFQGNSLPGQPGMPSDAQILEAVRACLREVDLDHVTKKQLKALAEQRLQTQLSAERRAVLDQMIDVELASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWU2</accession>
    <name>A0A6A6NWU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_365141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWU2"/>
    <dbReference type="OrthoDB" id="5215637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025536053" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="40842" checksum="D079884555A12F9A" modified="2020-06-17" version="1">MQPLLVASLFSLLPAVVLGECYYPDGSLATDFDYVPCTGGTFQTCCVPDDDELCLENGMCWYEGSPYRATCQDQTWGSSNCPQFCLTGESSDTFEFLYECGNSTYCCMDDYTNSDTTCCNDASLTFTLDDFDVVDSYGVSTTLTISEDTTIAPDPSSTSFTTTASGASTTTTSTSATTTGTSFLTETGRPDEDDEFPVLAVGLGVGIPVALLAAGGIFLAWFCIRKRSGKRDAAAAGPGAGMPPAGGAWPQQQQQQPLMQQQQQPMMAGQPGIMGPHGPVTYMAPGQPGIMDPHGQAGAGLYGGTMPPPAYNDAKRPQSQVTSPLQQQQQAQPWGPQTPSPHQGQVQLASPPQHQAQPGGYAQPMQGGVAVNELDSAAAGRPGVHEMGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX75</accession>
    <name>A0A6A6NX75_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-CoA synthetase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_323682</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX75"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000008">
        <property type="entry name" value="2,3-dihydroxybenzoate-AMP ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859:SF4">
        <property type="entry name" value="BUTANOATE--COA LIGASE AAE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="62"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="508"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="65995" checksum="12D47F54499E5187" modified="2020-06-17" version="1">MAPSASSGPQSRLARLAAHFLAPSSAPEPPSATPTAPEPSPPQPQPHGLNFHALSPTFFLPRAAAIEPHAPAIHHVTSNGAILRRTYESLSERALGFAYWASRCARVSRVGLVLPNTPAFLEATFGVGAVPGAVLVPVNYRLKSEDVAYVLEHAGVEVVVVDQEFVGLVEGFRERNPRVRVLVDADTDVVEGELSGEFDAAVLEGLRWDRENGKMGWEGLMAQARDEEEVFALAYTSGTTARPKGVEYTHRGAYLAAMGNVIESGLNFHDGKRARYLWTLPMFHAMGWTFPWAVTAVRGTHYCLRKIDYGHIWTLLKHEGITHFNAAPTVNTLLCADPAAERLPQPVRVTVAASPPTPHLFELMTRLNLQPVHVYGLTETYGPITKGYFMPAWERLTPNEKYGRMARQGHGFVTSLPVRVVKNGDDLPEEHVEDVKRDGKEIGEVVFAGNICAKGYYKDEEATRKLFAGGVLHSGDLAVWHGDGAIQILDRAKDIIISGGENISSVALESMLAMHPDLLEAGVVAVPDSHWGERPKAFVTVQAGKELTGEDVIQWAKHQSAISKFMVPREVEVVPELPKTSTGKVKKNVLREWAKGADRAKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXP2</accession>
    <name>A0A6A6NXP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_58963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXP2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="16548" checksum="91695A5B41AE6750" modified="2020-06-17" version="1">MASSTRSGPGAGTGRGDPFLACPHVWPGLGIRKPRVVGRFGPWTSSPSTPLQCQFLGSCTGRSPCNRAFVNPVGWSNPTTGAQHSTHYLRCIFGSKPSGDGSEARRTSMTLFDALAPQQAWSLSCNFSALLAGESEDIRHTGGNMGASNAHARASGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXT7</accession>
    <name>A0A6A6NXT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_364994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXT7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="498" mass="52934" checksum="119507E185AB5DB2" modified="2020-06-17" version="1">MAPPPLVLGTTPSTTVTTLLPTSSLLASVGERVFPSSGTTVQTASAGIPPADATSLSGTGAPTPSVMVTLPDGTVPKEPPPEQVNTDDTLPRPAELGNHGTSLSSDSADSSADNPLTNATLVAVLVLCILFLLGFFGFLVYFLFFFRDNRRNCCMWGLFPFPILGRTTSSEMLRSEKDCEDAATVVVVDEKCSREHKTPPTSEAGAVVVVGDSSNEDIKPPSTLERPPSTPTPNGHDDSAAQLLPNQSLLSQPVAGEPQQPSQAQGTIVAEVSPPKSPTPTPFATAAHLTQPLSATVPPPPQAFLWRSIRTQHGEQQQTQQAGKGEGQHGRDHNRDDAFPHPVYRHNLARPKALERMQLGAHRAAQHHRHNHGGWMHIGDGGGDGNPHSNSNSIGAAARDLTRSGTRMMQRASRKSQELVAEALARDPSHHGFSAGRKLSKKVRRAVMEHEGAGGRTDGFSRIETRGGGWPLEEGKDGNGDEGRVERENSGTSIGKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY87</accession>
    <name>A0A6A6NY87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase activation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_372160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY87"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF125">
        <property type="entry name" value="GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="223"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="443"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="520" mass="57910" checksum="D1604EB67C7D7D57" modified="2020-06-17" version="1">MASDAASVPVGNVSGSVDDSAIRNGSVKSQSVPHINSDLGTTGSNRKTVRPNKFNLLRSRSIRHEQSHHTRQKPSTPHRMLDPAEIKPSKYTPDMAGMKTAPLEKDRSFRDLIGSGIRGRSADRHQAVDSEDDTSTSLKDRKDPFSFSSSFKESGGAAFLSNIRSQGTKAADGIGKAGKGIFGKLARSGSSHEREAMPLPENYVCKVINLPLVEQTRKTRISKRLEASKDKTEFWMPALPWRCIDYLNMKGCEEEGLYRVPGSGKEIKNWQMRFDTEYDINLFDEPELYDINIIGSMFKAWLRDLPDEIFPKTTQHRIAEECAGAKETPQMLKDELSKLPPYHYYLLFAITCHISLLHSCSESNKMNYQNLCICFQPCMKIDAFCFQFLVLDWRNCWQGCWTEKTYLAEELRIMADHENRTGSPAPSHGTRMTNGTNVEDSRAVSSSESSKHSLTGSSTPDRSRHGGTGHSTQKSSHDESVTPTPGDQQPKKAEDAPKLSPVPLYSPMSVPAFAGSDDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZG0</accession>
    <name>A0A6A6NZG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZG0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="17882" checksum="AC668FAEF4F95608" modified="2020-06-17" version="1">MASATAGNGSARRGAYAPARKAGIMNAPAVASDGAATVILTNEDEDDQLVSRDERGRYRIEVPAVSVMPPVTVERELEDERQRERRLLQTYRRHLDDTTHALHASHRASRGPASSPRAEHARRRLVMQVEALRESLRARLEATVETLAEDEWIFRDAAEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZR3</accession>
    <name>A0A6A6NZR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7025 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZR3"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7025" evidence="1">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="25221" checksum="8D378176B555EB4F" modified="2020-06-17" version="1">MLLLYFRKISRSTGEHVNFDGDIFSFSDIAVEIKSFKGARRITSLPCYPIGYHRDKESIERQLINHGRKFTELAGLKYKSYTSNPELGLARRNDREFELKCEQRSSSMRSLRLGSASTSSQRVAQALVEVYTIDLPERTRTPKIGLSEHRFSPHVLIDQPTDARASTTNGNLRCGEAPLESHTVVANILWGRKSLISPRCGRVVSEGSRFNTPGSQNWAPSHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P003</accession>
    <name>A0A6A6P003_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P003"/>
    <dbReference type="OrthoDB" id="5424462at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF2">
        <property type="entry name" value="DUF3602 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="18721" checksum="70A656751C1ECAC7" modified="2020-06-17" version="1">MTSFRSSTSSNTSLVERQSSEVYLRSGIGGAGNYRRKSSITLAAPAVPIIGPQSRAGSFSSGIGGAGNFHKADERAVLSFDEELARSRAIGRNAPTAYHVGIGGAGNRKHRGVSPSITVTASADNIGQQQTYSSEPLPFGAVDSFFRRLSGASRSTSRDASPAPSDTKRNGSIRSSLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0V6</accession>
    <name>A0A6A6P0V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_344402</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0V6"/>
    <dbReference type="OrthoDB" id="1747771at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374:SF1">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE PAD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="711" mass="78987" checksum="B84D2E232192659C" modified="2020-06-17" version="1">MDSQTTREGDSADVDEILRRKRKTREYKACYPCRKRKVGCDQAVPCGRCVDRHHPELCTWHPPGEAHPPASQVQHAQTGVLYASSPPSNGNATITVRREDWDNLNAKLSAVEKAMSDLKGHMRQVSDGPPGTVSTNGFSPSEPIATPQYSNPPIDSHTRHVNAHGVHTESEITGQVVHLGGSSVPALVMALGRRNNGNEAEFKEILGKSILPLFGLDNESSTYPFVDLWGLPHGSITRVEQLCSTLPGDSECMSFLRHYRDTAYVVYPAVAEIDKLESDLLTFLMNRRLSLGEGIREQSAYGYSLSWLSILFAALASGCQVSGLPRKERELTSQVYVCCSFECLRATNLFSHTNLETIQTLLILGNVISNNMNAGVAWSLLGLTLRLAQSLGLHRPCPESTPEELKVTRSKIWWALLWQDSLLSITYDRASASAMTFEHPLPTFDETGPGYKPYRYCMYRLCKVGLDIVRERACYPRNSSQALERITEHRNELQNIMMEAADYLKDSRRCTTMRDQLEHWALYLHMSYIASELCRPAISPSTPDYDLTKTLRKACIDSLANTVEAFLGLQNVTSFATRSWAAVHRSLSSALLLGILGEPSRNERVRMLVGKLIAVMSEITSTVDPAELSGPISRSIVALRRWTAAGSQLLPSGTTEAPDVTPSMPFYGFDEVDLNPNLDPALFPQSPLARIDQEYSPHQVMDTILWGGKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Z8</accession>
    <name>A0A6A6P0Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_15287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Z8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="336" mass="36618" checksum="6A2444E2467C1D8C" modified="2020-06-17" version="1">MRPTRRRGLVCANEKKGEAAPVAFQHAKAGARFASTSWPTTPPGAGLTAPASTPACHKGRVYLNAVGLSEAASGARGFTSQLRLAPRRTDPWPRLKRQSTRNPAISFPYFFFPSPSLYVSRDFQNLAGLLLQTPSPSPPLFSCDVRRPEVRDRGSQLPSRRKRHAFRHRLFKLRPLSFLAARAPPSAAMLARKRGREDDDEGYDQYASCYGDAGVHGVRHEKVGARVSSQLAGTSQPWRSSAGSMKPESAAGATMLSRPPYTRAHASERSEETRKVLKLLNLSCRNVATPTRPPTQQCCILSTSTLIPTAVPSAERRNLRPCASSISSLSIASSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1S9</accession>
    <name>A0A6A6P1S9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative aryl-alcohol dehydrogenase Aad14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_285457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1S9"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF2">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="376" mass="41729" checksum="7FF6EC415CD0EA0C" modified="2020-06-17" version="1">MAHILTPAPAPATELGRYRILSSTAGVRVSPLQLGAMSLGQAWVSELGSMDKAASFKLLDEYVSSGGNFIDTANDYQDEESEAWLGEYFETRGIRDQMVIATKYTTHYRKHDLGVAGINYAGNHKKALRLSVEASLKKLRTSYIDILYLHWWDHTTSIEEIMDSLHVLVEQGKILYLGVSDTPAWIVSAANYYARASGKTLISIYQGRWNIMMRDFEREIIPMARHFGMALAPWGVLGTGKFQSKKAIEERKQKGETLRSIQGSEQSEDEAKISEALCNVAAEHGIESPTAIALAYVMSKYPYTYPIVGGRKVEHLRDNIKCLKITLTEQQIEYLEGIIPFDPGFPNNLIGPDPKLIGKATGLLAASGNFNFATAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2A2</accession>
    <name>A0A6A6P2A2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Quinon protein alcohol dehydrogenase-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_385296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2A2"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="77"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="618"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="660"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="702"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="753"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="795"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="837"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="879"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1017" mass="111422" checksum="77DF7F9626372700" modified="2020-06-17" version="1">MSFSNPTRHRRNDAAGSGNIYHNPQVSGGKAHFGDTYHIGADDPLSRLPCATDAPFNSFSKQHEPECLEDTRTALLQEINRWVDGPDERCIFWLEGLAGTGKSTIARTIARKYFSLKRLAASFFFSRGGGDVGHAHKFVSSIAVQLAHATPTLRQHICDAFTERPDIVDQSLRDQWQRLVLGPLARLDGDDGRWPYVLIVDALDECDNDNDVRIIVQLLAEARSSAQGRLRVFLTSRPETPIRSGFHQMPAGGYHDFVLQDISPSIVDQDISKFFWHELTLICQDSFSDFGWLRAETVGTLVQKASGLFIWASTACRFIQDGFLPEESLETILNGSTDHETPEEHLNDLYTAVLQKSTQQYREQDKPKVLGFLRDVLGTIVTLFSPLSVDSLSGLLFFQGAVVNKTISTLHSILNIPTEPSRPLCLHHPSFRDFLLSPERCTDPKFRVDEKRTHAKIAENCIKLMSTSLRQDICGVKAPGMLVTGVADSQVQRCLSPELQYACLYWVQHLQKGGSVLCDEDRVHQFLQKHLLHWLEALSWMRRISDGISSVISFQSIVKLSSFIHDMRRFILHSRSAIEQSPLQTYWSALVFTPTKSIVRVQFENSVDQDWNALLQTLEGHTDSVSAVAFSPDGARLASGSDDRTVRVWDAATGALQTTLEGQTGWVAAMAFSPDGARLASGSYDRTVWVWDAATGALQATLKVRTGSVTAVAFSPDGARLASGSADGTVRVWDAATGALQATLEGHTGSATLEGHTGSVRAVAFSPDGARLASGSDDRTVRVWDAAADALQATLEGHTGCVLAVAFSPDGARLVSGSRDQTVRVWDAATGALQATLEGHTGSVRAVTFSPNGARLASRSDDDTVRVWDAATGALQAALERHKYRVRAMAFSPDGARLASGSGDDIIRVWDAATGALQSTYNTSGIVNRLSFSDDGTFLLTDRGFLPLDISSAAVAPSQQHLSEHIFVQEQWVTWQKKRMLWLPLDYRPNCMATSGNVAAFGHSSGRVSIMEFAFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2S0</accession>
    <name>A0A6A6P2S0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Purine-cytosine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_212934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2S0"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11484">
        <property type="entry name" value="SLC-NCS1sbd_CobB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="523" mass="57313" checksum="9F83EFBCFA63773F" modified="2020-06-17" version="1">MAAYANDIEKYGVETEGDGYDNKRPSFVDEGGAVHGESFEYGDSLYAKLQRLAGKLKIEQRGVERVPEDERTDTSYLNVGSMWLACNMVVSSFAIGLLAKSLFYLGFVDAILTVLFFNLLGVIPVAYYSTFGPRFGLRQMVLSRFWFGWWGVKLVAVLNILACIGWSSVNCIVGAQLIHAVNNDVPGFAGIIIIAVCTFFVTLFGYKVVHAYEFWSWIPTFIIFLIILGVFAHSGAFVNIPMGAGTSELGSVLSMGSVVFGFATGWASYSADYTVYQPVTQSRRLVFFSTWLGLIVPLLFTEMLGVAIMSATAIDDGDNRYQEGYDASGTGGLLGAVLFPPLGDFGRFCLVILALSIIANNCPNIYSVALSLQVLSRWTTQRVPRFVWTLVGTCAYVAISIPGYSHFEDVLENFMNCIAYWLAIYEGVSLTDHFLYKRGFGGYRPEIYDRPGKLPPGIAAVFAFCCGVAGAVTGMSQNWWVGPIALHAGEAPYGGDVGFELAFAFAATSYAVTRYFELKIFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P392</accession>
    <name>A0A6A6P392_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_220035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P392"/>
    <dbReference type="OrthoDB" id="5358884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="25756" checksum="7A7E8CB88521FC2F" modified="2020-06-17" version="1">MSFPAPSFSPPPKLSGQNWAELQPDGTAQVVSSSGNIEVVSGPGPKTNESFAPTHLYPAPSRSASLFGWGKKATFAFLGVLVAIIVGLIGALIAVAVSMSSDSSDYSSCPGQASTTNSASSATTSFSTTTVAVTAVPTQGFATLDCPNVNDTSYETPTAFSFTKRCGVDYRYQGGPADIVALTAYSFDACIDACGSYNHNNGAGSCFGVAYNPDLTSSLPRDYGNCWLKPTNDGTFFSVENPIAVATLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3D6</accession>
    <name>A0A6A6P3D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Autophagy-related protein 15</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_320388</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17855"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3D6"/>
    <dbReference type="OrthoDB" id="58570at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005775">
        <property type="term" value="C:vacuolar lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034496">
        <property type="term" value="P:multivesicular body membrane disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046461">
        <property type="term" value="P:neutral lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000129">
        <property type="entry name" value="Autophagy related lipase Atg15, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050805">
        <property type="entry name" value="ATG15_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175:SF2">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025692253" description="triacylglycerol lipase" evidence="20">
        <location>
            <begin position="25"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="21">
        <location>
            <begin position="286"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="528"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="463"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="528"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="571"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2457983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="622" mass="66713" checksum="ADC7601105A4058C" modified="2020-06-17" version="1">MPHARNLLLSFLTTSSAVLQPALAFSLFGPAAAGDDAQLPVLPPLEPGQPGGSPPPAQAAELDFKLRHIFHHGTYKYPELHRRLDIPDDARLTVQMEGDSGPSPAPEHLYARSRPLRIQRLVDRRRSTIDEILEQGRMRGKAVELPASAWTTDEIPGPNVTDKETVLSFARMAANAYDTGPEESEWTEVGGGFNLTDDFGWETDGLRGHIFTATNNQTVVIGLKGTSPAVFDGSETTTNDKENDNLFFSCCCGQGGQYLWRRVCDCQTGTYTCNSTCLTQELKAKNRYYQAAQELYHNVTELYPESDVWMAGHSLGGAVSSLLGLTFGLPVVTFEAVPEAMPAARLGLPTPPGFHVGMHQQRPDTGTFHFGHTADPIYMGTCNGASSFCTLGGYALQSSCHTGHVCAYDTVGDLGWRVGLGTHKIRSVIKDVIEKYDEPAACERRENCTDCFNWKFFESNGTETTTTSGLATSTSSSTRTRTETCKTPGWWGCLDETTSTGSATTTISSSSTSTCETPGWFGCKDPTMTTTSSTSTSSSAAPSPTVTTTSEPSSTTTTCEHPGWFGGCNDPTTTTTSSTSSSAAASTTSTASSAPPASPTCVARTWYGRCKEWSGVFGSSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3R2</accession>
    <name>A0A6A6P3R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_341531</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3R2"/>
    <dbReference type="OrthoDB" id="10254973at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="135"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="321"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="481"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="743"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="872"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="972"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1180" mass="135881" checksum="2D87184BC01B5706" modified="2020-06-17" version="1">MHGAAGLVRFYLRALARRVCPQAHHLLFAASVSPLRSYLWTTMPGLTVPHRRRRSEDFDGRTSDDNVEETDGVASPYSQQSHGSKRTRLDDSSAPSPESEEGAVASPERVVPLVSSRRQQGVNPLGAEKHQPGSIIRVRVKNFVTYEAAEFNLGPSLNMIIGPNGTGKSSLVSAICMGLGWKPDVLGRASEAHSYIKNGTREAEIEVELAAGPNQRRNPIITRNLRKAGNKSSFTIDGRPATNKDVSSLAKSFNIHLDNLCQFLPQDRVVEFARQTPEELLASTQQAAAREEMTAWHRDLKKLGAERKAKLKDHAGHKDHLVQLQGRQNAQRGDVQRLEERRDLLEQVKTLRRMRPMIEYQEAKQMVEELKHRKQEAQTELDELKARVEPTLRAVNAKETYKEAKQKEVEKAERMAQRCADDAARYLGDVESVKGEIVHSQKEREAAIEGDRKRKQDVIRTEGNIARLKRQLEEPLIQFDVSAYNERIRAKTRRIRELEGQIGDILRSQGEHRGQIASRQQEVDENNRRMENLNSQVGRQEEILRKKSPDTAKAWIWLRDNQHLFRSKVYGPAAVECSIKDPQYADAVESLMQNNDFLAFTCTSREDFKILQEQLYGRQRLKNISIRVAAHGLDYFKPPVSDEELRNYGFDSWVIDCISGPEPVLAMLCDSRFFHKAAITLRDHSEQQFERLKESPIQLWIAGRQTYQITRRREYGPGAVTTMVRQVKRAAVWTNQPVDTEFEQRCRQRNIELNGEIQEIRAEFERMQNEILEHRREARSLEEEKRALETEKAAKQKARAEREVLPTKLGNEEFRLRNLRDSGSQVIERILEIDAKVDALNCQKGEVALLYAQRVEMLQKSLVKVYGAQLQLLEAESDVRTMRQQNQNVRELLEQRAGELNTIRQEHKEWLRKARVLQRKALDVHNNATEQEQELHRNFDSASIADLQQAITTTESRIECLEGGNPEIIQQFERRERDIGALENTIQSLEQQLEELNAHIAKIQQKWEPELDELVTQISDAFAYNLSKLGCAGQVQVHKDAEEFHLWAIHILVKFREHEQLSLLDSQRQSGGERSLTTIFYLMAMQSLARAPFRVVDEINQGMDPRNERMVHERMVEIACQEHTSQYFLITPKLLHNLMYHPRMKVHCIASGEYMPKDYKEMDFKRLASVAMRLRHQAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P432</accession>
    <name>A0A6A6P432_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription regulator HTH, apses-type DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_263586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P432"/>
    <dbReference type="OrthoDB" id="5562739at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR XBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="1">
        <location>
            <begin position="66"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="23338" checksum="B7A5E5C8A4AA2DE9" modified="2020-06-17" version="1" fragment="single">PTPKREKLPKDAAVFTKAEFRGEVLFWPQEAGPDEKLAAAHRKFELNPMGHIADYCRHIPYKSDKKTFVAKTGRDSFEVFQYTFKLPWQEPDENGKIPEHVVMWDYNVGLVRITPFFKCFKYPKTMPAKCISQNPGLSDLVHSITGGSIVAQGYWVPYKAAKAIAATFCYEIRHALTPVFGPDFVNQCIPPGSPNFQNFKINPAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4F5</accession>
    <name>A0A6A6P4F5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_282753</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4F5"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="43169" checksum="E52B2DEC80B311F3" modified="2020-06-17" version="1">MASRRVPRTFRATNVPCSTSKSSLEAAVCTLCDPTEKDSIKIRTTIAPSCTDAKRSQTAIITFDPSTPQKLAQASKVYIIVDGADVEIDSDFFGLTQLYPPRGKKVSADIVAVTGLNGHAFGSWSGGPSKKMWLRDFLCEDDVLKTCRTMIFGYNSKLRDAADHSMFEYVRSFLGELSKARSSEEERRRPIIFIGHSFGGNIITHSLPYAKTYESDAKICSIVKATYGMHFFGVPHNGIALDDVVDMVKDGSKPERVELVNEIINTAKSLTFPKENFKNMATNLKIVSFYETNMTKKVIKVRGESGYGRDGDHIMVVKRESAVLGLPSSIETAIPVDENHSSMVKFPTRTNKTYEHVRSFLQDWVKAAEKVVSERFGMLVLEFPLLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4J2</accession>
    <name>A0A6A6P4J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_283635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4J2"/>
    <dbReference type="OrthoDB" id="5359669at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="319" mass="34242" checksum="6548D2528ECF6D02" modified="2020-06-17" version="1">MGLNYYASAPTLVLPPPSSTNLFGDGPNSSHSLNPPPTNFRPRFPRPPSINYLATSANLAGRKRSRDEVAAEHEDLDDGSRVAPVEPPKPRPEPIMGPGMTLIYPDEPGFSIAADSQTGTWAEEKKQAEDEAATTAASSRPMAVSRKSARRPAPADLESVSPTAALCSSSTPRSPEDGIIDRLTLVLGVGWKRVYGNDAVADAARGWARYIENHYPLAKPTIMLHSERLQAYLVHAFDPIDSCEGFWLFQDELKFGQAVGESLDAVVANLTAQAEIRFEGEPIRAQSRRPSDPSSITVVPQPMNGAVAVAVAADVDMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4M8</accession>
    <name>A0A6A6P4M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_341075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4M8"/>
    <dbReference type="OrthoDB" id="5272500at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="331" mass="36013" checksum="7D0DEAFA4C8C3F05" modified="2020-06-17" version="1">MEPTHSFEGSSEALHSPFSIRPEDLRSLASSRAFKILSSYLASVSPRPFCEYHALNCGHEAKSTFVLHRDILHALLMPIRQLYERSCTLASAALCSGKAEDLELAYRGDARSAFVWLQCFLESDEEDEWCRSAGCAACNVLHALSTESAIRLTMAAIRVAAEHQQKARGGPAFPSFEFLEPALRDALAADPFWGRSTFDNIAPKAPVLAQGISALMDQCAELEVLVSSPAPSPAPAPPSKKRPPPFAPEDQQSAVILIGTDHKSGAKIRPSRLAKRQQRLQQEEVALIQRALAQCWGAVALNGAGFKGLRTRKLEQVLGASSGRRRSLTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4P0</accession>
    <name>A0A6A6P4P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_362926</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4P0"/>
    <dbReference type="OrthoDB" id="4078635at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8 10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="97"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="207"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="423"/>
            <end position="427"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="538" mass="59635" checksum="18F43A3E8B993981" modified="2020-06-17" version="1">MSSIQAEESRYQEEVKAVKQWWTDSRWRYTKRPFTADQIVAKRGNLKIQYPSNDMSKKLWGILEQRSKSKDASFTYGCLDPVMVTQMAKYLDTVYVSGWQCSSTASSTDEPGPDLADYPMTTVPNKVQHLFMAQLFHDRKQREERLSTPIANRGSVANTDFLRPIVADADTGHGGLTAVMKLTKLFIEKGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGTDLLAIARTDSEAATLITSTIDPRDHAFIMGATNPALQPLNDLMVAAEQAGKNGADLQAIEDEWVAQAGLKLFHEAVIDTINSGVHVNKQGLIKEFMAQSKGKSNAEARAIAKGLTGVDIFFDWDSARTREGYYRYKGGCQCAINRAIAYAPYADLIWMESKLPDYAQAKEFADGVHAVWPEQKLAYNLSPSFNWKAAMPREEQETYIKRLAKLGYCWQFITLAGLHQTALIADTFSKAYAKNGMRAYGEVVQEPEMENGVEVVTHQKWSGANYVDNMLKMVSGGVSSTSAMGKGVTEDQFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Z1</accession>
    <name>A0A6A6P4Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_340454</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the chitin synthase family. Class III subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Z1"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF11">
        <property type="entry name" value="CHITIN SYNTHASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="491"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="624"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="752"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="792"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="57"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="827" mass="92779" checksum="7334E905CE35EA82" modified="2020-06-17" version="1">MPGAGGHLEDPSMQFGVPGGRAPSPYARSETSSTEAWRQRQNPLAAGGGSGLKRNATRKVKLVHGAVLSADYPAPSAIQNAIQAKYRNDSETGSEEFTHMRYTAATCDPNEFTLKNGYNLRPAMYNRHTELLIAITYYNEDKVLTARTLHGVMQNVRDIVHLKKSEFWNKGGPAWQKIVVCLVFDGIDPCDKGTLDVLATIGIYQDGVMKRDIDGKETTAHIFEYTTQLSVTANQQLVRPHDDGPTTLPPVQMMFCLKQKNSKKINSHRWLFTAFGRILNPEICILLDAGTKPGSKSLLALWEAFYNDKDLGGACGEIHAMLGRGWRNLVNPLVAAQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKMLGPKGIEGMNIFKKNMFLAEDRILCFELVAKAGSKWHLTYVKASKGETDVPEGAPEFIGQRRRWLNGSFAASIYSLMHFGRMYRSGHNIVRMFFFHIQMLYNVFTVILSWFALASFWLTTSVIMDLVGTPSDSNGNTSWPFSEDVTPIFNTIVKYIYLAFVMLQFILALGNRPKGSRWTYITSFVVFGLVQFYLIILSMYLVVRAFTNPETEAFDTDGDTGDFLASFFSSDGAGIIIIALAATFGLYFVASFLYLDPWHMFTSFPQYLLIMSSYVNILNVYAFSNWHDVSWGTKGSDKADSLPSARTEKAADGKHTVIEEVDLAQADIDSQFEQTVKRALEPYHAPKESTAKTLEDSYKSFRTNLTTAWIFSNALLAVVITSDNFDDFGFSNNANQRTARFFQALLWATAFLSLIRFFGCLWFLGKSGLLFCFAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5B5</accession>
    <name>A0A6A6P5B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_362675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5B5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="239" mass="27972" checksum="E4EAAE7605353810" modified="2020-06-17" version="1">MTSQMVAIAPIPDLELKIPIYQLNTQFILAVYPTDDLSSDTDYTNFVGYELIPWSWIRSHSNHEVLRVAQNEESGTTVGNARNIIWKISAAGIAQPEDSITLLMNAIKYYQMIDSFAGWPLDFMIEEDCYGVTKLMDEMRFVDWFPRPMTQKIWAYIKNDPALSDKWRPYFYLFDTQRLPDVEYIGKHSYFVYMVTKYIAASLITEYFLQSKTSWSEFSRNHSDCVEAYSHRPSNLIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6B4</accession>
    <name>A0A6A6P6B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 small nucleolar RNA-associated protein 6-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_269504</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6B4"/>
    <dbReference type="OrthoDB" id="28112at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="6">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="31157" checksum="A2FCB6617A678EB1" modified="2020-06-17" version="1" fragment="single">MASVSDAARFSLETSAPELNELLNKKIFNREQINKIARARSDFEHHINAPGTGLDKWNRYIKYETTFLKLRRERARKMGVKGLNHAGAGRVFRVFDGAVRKFPGNVDLWLDYVKFAEHEKAFSRVAEILTRALRLLAGESKLWIYAGRYAYGTHRDINQARQFLQRGLRFNSKDLDLWLTYLELEMKYLDSIWARQELLSGGIGGAPEPSSRDGPELDKIQLPVGPMATSNVLTKALDATKVGPYDTNSVTLDPSTAPPIVNGAIPEAVFRGIMTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6B6</accession>
    <name>A0A6A6P6B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_282129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6B6"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="53"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="24587" checksum="1A3FEBE03E1C858F" modified="2020-06-17" version="1">MLPLRVARSSPGGSASAVLRALRHVSSRVSRVQAGEDELAQARQWLAKFGKDTIPQSICEVSYSRSSGPGGQNVNKVNSKATMRVKLDDLQTHVPRLIIPTLQSSRFFAKRSDCLVFQADEERNATENAATCFRRLKQAISEAAKMVIPGETSAEQKERVKRLYVLVTHAPETPSNRRPGISPRKVERRRRRRPTRRRRVTARNHSEKIRPLRWPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6K1</accession>
    <name>A0A6A6P6K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_338747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6K1"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025599962" evidence="2">
        <location>
            <begin position="27"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="62065" checksum="5A838A0A946A4B6F" modified="2020-06-17" version="1">MAIAALKAWFSIALLLSATLTSQAAALEPSGTISKQAPHQTVHNAAHIFNALHSSMRQWGSSINHNGQSFFLASVPAHTQFYHGTSIDWPVTGMEWLAFEPEHALLFARRFPPNDTSYATDSILRKQGPQKQQREGQDQRTLPTHPAKARLLAQEQFLNDGRKKPPHHVPSEPGFLHVYRTRHPLRLLYLDGLSAGKTTNGTLDSQDLILLQTALPHSPFWDFERAHQLCDLARTSWDGRVDGFLRMEAGFEVILCEFEKHLDTVRIGRAGGGKEPGFWAAAGDMFSYWRAVTDRYWGIGGERVKLGYERFVSVYADEDVDLWDGGKAKMPRLGNVSREVREKLKAEVDAMVMGEPNPWVGLEKGEGVNWQEVVDLIVRRYADRLKFMVGEDVVSQPKDLHAELDRAVRPFLDYDARDMEAEEWRCTTHFLPWDADEDTLAARAVMDVSKRICGTLLVAHNLTLSAADDSNSMAQGKATMSAKNLKALIEYLDWTVWKECGGCGYDEVCFVPIWPYGTKEDHENPGCANASELVSKTGYWGRIWPPRNETEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P733</accession>
    <name>A0A6A6P733_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5563754at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000203">
        <property type="entry name" value="PH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058155">
        <property type="entry name" value="Skg3/CAF120-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25381">
        <property type="entry name" value="PH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="69"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="869"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1255"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1299" mass="142384" checksum="C2204F26117B7C50" modified="2020-06-17" version="1">MNPSSSSHSLEQPARESPTTRPRARSDSRTSSRPPSMLQTYQPPVMDVARDTIPELLPIFSFLNSHSNKLYQEGYFLKLHDLDTRGRPSADRTWTECFAQLVGTVLSLWDASQLDVAGEDGEVVPSFINLADASIKMIESLPMNGQGGQTLQNVLSISTAANNRYLLHFNSLNSLTQWTAGIRLAMYEHSTLQEAYTGSLIAGKGKTLNNINMIMERARVKHEDWARVRFGAGTPWRRCWCVISPPDEKEFQKLQKALKKGSAYNRRSPVLKGDLKFYDTKKITKKTNPIATVSDAYSAYAIYPQSKPLVDQSTLVKIEGVVTIHSQPESTTEGFVFVMPEVHPAVSGFEMMLRFLFPIFDVFNLYGRPNRLIADPLDPRGLMFAMPTDRRYGYLELFDVAGLIHSEGSQNWTERQWRKQMKDLTAKRMQSAPSRDNSRNSRMGSRRYTINRSSLPPSRSGVLRFEDGGGSTRSQPSTRHGSPTRANEPSGPKRVDSAPPNAANVGGLGHRRSVSEANAAPAYRHFQADAPSRLAYGTNVDDRPPTPPQHRELPERPTMDSPGYETASEGREYASPESGLGRGDSDENIPAITSTGPALTPVAEPPNFLHAPSQRPPNQPYQAPELRRANSAIDAATLRQMADANHAMNPNSLAAAGAAAAWRASPDGTRSDMRQNSDERMDMGQRGVFADPRDRGAPADDYVHHQGMVNSRAQLPAQRGRLPTIPASPYIPQTESPTSGTVFEPAAPPVPEHGTPMGLYMPSQSAPPQQNPNAPTDFAARPIPQRSATSFSIHRKPVPGRGSVELARADSRSNSSVGSLRNHVLDQNAIDQIGTAPLGRTATQATGSSHYSEPEDLSATPDYASTKSAESKHSVERPRHGQLKTVGHSAEEPKDIVVGDIHYGHRTEREAKSDLPSVDFGPTYALSPDRPRPGTSGTITQGSHSRDRSGGATPRMTESNRQSYFGATSPPGHQRNSSRSPGTPAEDAFGRADHRSMAWQPGMTSSPGRAQTPNRLTAEEWVQQRAAAASQPHLVPRTSPTQPQNRSKSAGNTPPTSRNPSGDWSQLQAQPNRTPPLESRRSPRPHSRGPSQTLLSDSEDYSKRLSAREQEYVARATGQPFLNMARPEESARPPSASGLVGAIEAREKEKQDFKDAHSSSRVVQEAIRQRQQQAYAQAQANSMAQSLQYMGLDSSQQQQQQFMMQQQAQGPMQQPYGQPAFNQSQQGFYPQHGFPGANAQGWGGQGSPMGGMSYGGFPQQQQQPQQAPRQAYGASFFAQHPEQNQGQGVYPRQQGGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P737</accession>
    <name>A0A6A6P737_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS sugar transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_336551</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P737"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF20">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="39"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="62372" checksum="18C462C9B9D20DED" modified="2020-06-17" version="1">MAPVGGTASFEAAAFARRKELAGKSGPLALLNNLKVFGIACFACLGGLLYGYNQGVFSGVLTMPAFERNMPNWVGDDNSTRMGWLTAILELGAWFGTMYSGFLSEIISRKYAILVNVAIFVVGVIIQATAVVGDGHSEILAGRFVTGMGVGSLSMIVPMYNAEIAPPEVRGALVGLQQLSITLGIMISFWIDYGTNYIGGTGDGQHNAAWLLPLCLQLVPAVLLGSGMIFMPFSPRWLVHHGRDAEARKVLAGLRSLAQDHPLIELEYAEIRAQALFDKRTLAENFPHLSEQTAWNTIKLQFVAIGSLFRSMSMFRRVIVATVTMFFQQWTGINAILYYAPQIFEKLGQDDNTISLLATGVVGIVMFIATIPAVMYVDKLGRKPVLIVGAIGMAASHLIVAVLAAMNEDQWPTHQAAGWAAVVMIWLFVIHFGYSWGPCAWIVIAEVWPLSNRPYGIALGASSNWMNNFIVGQVTPDMLTNLRYGTYIFFGLLTLGGAVFVWLVVPETKSLTLEEMDLIFGSPGTAEADAERMREINRELGLDDLVQHIGVETGVDEKGAHVADLKEGSGNHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7H2</accession>
    <name>A0A6A6P7H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_419561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7H2"/>
    <dbReference type="OrthoDB" id="3791134at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="119" mass="11661" checksum="E5610A57A0E34503" modified="2020-06-17" version="1">MAPNDNWISRQVQAGVAGVGNFAGGMVNSVGNGVTGAGRGLGNSITRTTLGWGDSVRTYGNGVKDATAASGTRASTAQNPLGLSSTSAGARAQLKTQGNKKAASGRTGTANDPLGLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7K3</accession>
    <name>A0A6A6P7K3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_336688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7K3"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="8639" checksum="DBACCF963BD4D4E0" modified="2020-06-17" version="1">MTMSARECPGKLSSKLDLEQLSGQAIPVNSAEIQWDESPNDNPTTNYTVPGRKCPNCLAKGQTVWVIKGKCCPQCGTVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7P0</accession>
    <name>A0A6A6P7P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_316596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7P0"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="139"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="472" mass="49320" checksum="CFA160EE43119940" modified="2020-06-17" version="1">MRPTRAIRLTVSSLNSPAPPVPWTAARTLFTRAAAPTVGRSSTALPACRSELRASARLPPSSSSAYTSPADNAALRLRTSSFHTSARLTSSSSSATAPPRFSYRIAASYSAKGRRFNADRNVYAFNPFVRLKRTATELQRGKRDKKNRPESGQDAFFVAHVGDAGTSGGSGAGGSELNDGALAFGVADGVGGWTDQGIDPADFSHSLCDYMASGATGYPDAFPARKSGSTAPLMPKDLMQYGYDKVMRDNAVKGGGSTACVVTAQADGHFELANLGDSGLMHFSPNAVRFATSPQTHAFNTPYQLTKMPPRILAQMALFGPNQRRGGGGGYHAETPADAATSSHAVRHGDVLVLATDGVWDNLSPADALRLVSRYMGGLGGWVAADGDGGSESSRRGSAAMQEGVGGGGAATLQEMLAVAIAREAKAASLDHRRDGPFAREVQRNFPGENWHGGKADDICVVVAVVVGVEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P862</accession>
    <name>A0A6A6P862_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_281501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P862"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000118">
        <property type="entry name" value="Phosphatase 2C-like domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF24">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="146"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="446" mass="49246" checksum="2B51116EBA8DDACF" modified="2020-06-17" version="1">MPPPARPSAVQHLLPARCCTRRVTPATVAARGAQPPRPSPSTRPHLTPASASPPPPRLLRPPKAAAWLPRRAWLRTDTRREPRHGTTTPVPDDPQAFRSKSPFYFEAGYALFAKRPSRPFPPPFLSYPSGSFSDPLSTHHRSRDRRSYVNGEQIRGITNGDDAVLVSDNFIGANDGVGAWAQKDRGHAALWSRLILHFWALEAERDHYGETERSPAESSHPDPVAYLQRAYEQTKLATSKPTEWLGTTTACSALLSYAVNSHPRPVLYVTQLGDSKVLVMRPALWEGEDEDEDGDGTKAVIYETQEQWHWFDCPRQLGTNSPDTPTSNAIMDRIEIEEDDVVLAMSDGVVDNLWNHEIVSVALGSMRRWEKGEGGAGGNGLPGERTYADGMSYVAQEIVKAARKVAEDPFAESPYMEKAVDEGLSIEGGKLDDISVVAAQCKRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P865</accession>
    <name>A0A6A6P865_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_281757</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P865"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000014">
        <property type="entry name" value="D-lactate dehydrogenase (Cytochrome), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="12">
        <location>
            <begin position="141"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="567" mass="62129" checksum="2E4769DF19D46774" modified="2020-06-17" version="1">MLRRALRALQLARHHRGPPVYPASTTSTSQRILRKQSSSSAPGGGFALPTPSVKHFWTTGRVLLLSASLGTAAYYYGVSDGGFRAQDAWPAFRQISPRYGGKREMEKAIQELRWFLGEEAISTDDEDLRMHGYSEWSSINIDQLPVAVAYPKSTEDVSRIASVCYKYRVPMIPFSGGSSLEANFSAPYGGMSIDFTHMDRVLGLHEDDMDVVVQPSVAWMSLNEEIKDSGLFFPVDPGPSARIGGMVGTSCSGTNAVRYGTMKDWVINLTVVLSDGRVIKTRRRPRKSSAGYNLTNLFIGSEGTLGIVTEITLKLAVIPEETSVAVVTFPSMRDAAAAASKIMRTGVPVAAMEIMDEVQMSVVNRAGSTSKTWKETPTLFFKFSGTKAGVQENVQQVKRIAKAHKCGDFEFAATPQEQKELWSARKESLWSMLALRTEGQEVWSTDVAVPLSRLPDIIEISKKEMDDLGLFASILGHIGDGNFHESILYNAKDPKERAAVEKCIYDMVDRALEMGGTCTGEHGIGLGKKGSLVKELGLDTIAVMQSIKSALDPHWLMNPGKIMDLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8E0</accession>
    <name>A0A6A6P8E0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8E0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16893" checksum="986641BBEC839C98" modified="2020-06-17" version="1">MRRIPQRKYVERGKACISAPGFARWRGWAASGTPFAACGSSAACRSGYVPVLKLLLLSVHSLCRPVLRRHSALFCVAPVSRDERRRSRPLATARDPATSSPRVAVSCVSSTHAFTRTNQQAGAHRPRGGTRRLSDRQRLLRMCVQDAGSPPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8I4</accession>
    <name>A0A6A6P8I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8I4"/>
    <dbReference type="OrthoDB" id="3486565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="173"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="661" mass="73021" checksum="1266E8DD4EAA4543" modified="2020-06-17" version="1">MYDCSICHDLQPNLDSKGFANSIAVEYTKLQASTCSGCRVIFDGINAFYPNSEKELESNRLRLRPLEYNAGGPLNVVVLGKPSLEFYTQPDSPTAWPTLGAGRHISPSSNSESCLSLARSWLDNCSASHQPICTTTRSHTAPAPTRVLNIGNSSSEPFLETFAESTARSSIRYAALSHCWGGTDTICTLRSNLSQHQSRIHLSTLPKTFADAVVLCRRLDIPYLWIDSLCIVQDDADDWAREAARMAEVYSNAFVTIAADAAANSHMGFLGENNRHGCNKVVPVPCRDRNGGEATVFVRRAGLASTPSHSVHDRAGLSRSRLSTRGWVFQERMLSPRTLYFTAAEMGWSCRTEVACECRVNGRAQKKSQTVSDNESDRAWGTEWWRIVSSFSSLDLTFSEDRLPAISGLAAEMLQKLGPSADEYWCGIWKKSLPLDLVWWVDSVAMTSSSKSKRHEKSPYYAPTWSWASVTGPISSFCLLIPGSDLPRWTLDLKIIEGHCDPVGPNPFGPARPGACLKVSAPLVPVCVFNSQMMRRHSLKHPERTSELFAVSLTSHGQQQLPGTSDERSSNAVQGETKALVESIAPDVLSDTSKDSELLTQQCYLIIVVHSESVGETHCLLLRQTSHERSIYERIGHVVIGQISTFEEWESRASRQIITIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8V0</accession>
    <name>A0A6A6P8V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinetochore protein Sos7 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_377110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8V0"/>
    <dbReference type="OrthoDB" id="18959at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037475">
        <property type="entry name" value="Sos7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048781">
        <property type="entry name" value="Sos7_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37329:SF1">
        <property type="entry name" value="KINETOCHORE PROTEIN SOS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20882">
        <property type="entry name" value="Sos7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Sos7 coiled-coil" evidence="3">
        <location>
            <begin position="69"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="31554" checksum="5D683665DC1AA7F5" modified="2020-06-17" version="1">MATTTEELSDVLAQLQKPPDLEILQLNASLATEGDQNAEKRTSDVSDASANMENASLGDIEASLIYNKDLFSKLRFTYVEQNTKEKFLRAIIGDPPTFVEQQENAEFEAQLLEVKAALKEKKQNTAELVADLERRARALTHRYESVLARSAQLAALPDALASLESTIADLRARTTPPSSNPSLVLPLPETQSLVASREAELAQLDHELSTFQNSVPRKARELERLEAELRPLETHKTGAVAAAKEARRRKEESERGGMGDELEERGRWLRGVEAGLRQLLEVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P948</accession>
    <name>A0A6A6P948_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaJ homologue subfamily C member 28 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_413406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P948"/>
    <dbReference type="OrthoDB" id="1922282at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018961">
        <property type="entry name" value="DnaJ_homolog_subfam-C_membr-28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394:SF1">
        <property type="entry name" value="DNAJ HOMOLOGUE SUBFAMILY C MEMBER 28 CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394">
        <property type="entry name" value="YALI0E31793P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09350">
        <property type="entry name" value="DJC28_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaJ homologue subfamily C member 28 conserved" evidence="2">
        <location>
            <begin position="287"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="621" mass="66463" checksum="AE1F700B005E3048" modified="2020-06-17" version="1">MTLPSAVAPRARHICARCSRRARHALSPYHLSPLSARHLSSSRSSPPTEDPADTTSTGQDGSKNDNGIAAAETRPAEQRDRQEEDGPDLGAMSARLAQMSEESLEQGSRSARRAVGEAGFDQDLLRQLEDRIAGANFRNEHPQAFAQAGLRDGAGYGTRDMAGARPWTGDEAVEDTALRMLTDAHKPLRGGGGGGGGGGSGGSGSKVPSPRGVPRKVDTGRPSAKGGKGGSSGVRLANARDRSSLYSVLKDSSMSEQEKEQYRREMKERFQPGGRTTPATIQGLTALANQRIEDAIARGQFKNLPRGQKLERDYNASSPFLDTTEYFMNKIIQKQEIVPPWIEKQQELVATASRFRARLRSDWKRHAARVIASRGGSLSVQLVRAEAYAAAEAIDNPPRTKVAETVNSITPEGHLSQITLAGELKTIGGDGATPATAGESAAMSPTAAASAPHPSFPDPITATGPTSTAAPPPTPTTATSSSTTSPSPTGPVRPRALPPPFRDPDWLRTEQSYLSLAIDNLNALTRSYNLMAPDLAKKPYFSLDRELRACYADVAPQLPAAIRERALAPPPRRPDAVGHRPGGVMQRFGTGEGVRVADERSERRYGFREFWRDLFAGGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P978</accession>
    <name>A0A6A6P978_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_164678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P978"/>
    <dbReference type="OrthoDB" id="3642826at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="510" mass="51154" checksum="5C9E8636110237FB" modified="2020-06-17" version="1">MTASMVTAGTAGGEDEWIAEPFFVHEESSQSSLYVPTLPYGDNPPRATVASGNANDGEAGDQQQGENPFYCASCDGHIESSVPGGLLVGLDTSDLSRVTKVPQLDLPHSWSILLPTTTDNAAPSVHVEQSQSSLMQDGPSSGIDEGFTPFTVYTPRVESTQLMLPTPRPDSAHNTADMGDIPGQAASIVGSPNGPQVGADQAASVGGTVASIAAHIGAQNSNGPYVTVGDSLVPIGVVMGARGFGGSQGTASAYVIGDRTVPAGVPVTIQGTPLIVQTAAGRTELAVGTNTVTFAGSLYGQRPSITIHGVPYPAGPNGEYVIEGQTLIPGATVTIGSGESATTVALQSSGDITSVIVNGWTSVLPPSGPISAMAGVPPLLTVGSHTFSANQRTEYVVAPGTTLTPGGVVLVDGTRVSLTPGATALVVGTATVPLLPSATASPSAGLINIEDPLASASRPGSTPALPTASPTTDSAAAAGAAAATNINMLPIPWVVLLSLFGLPTMVLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9B7</accession>
    <name>A0A6A6P9B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Magnesium-dependent phosphatase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_167700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9B7"/>
    <dbReference type="OrthoDB" id="2865258at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07501">
        <property type="entry name" value="HAD_MDP-1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000155">
        <property type="entry name" value="Putative magnesium dependent phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035679">
        <property type="entry name" value="MDP-1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="23282" checksum="3479C8E17F3E00C5" modified="2020-06-17" version="1">MPRRRMAAADNTASTTALPASSLLPDTFTDGLPLPKLIVFDLDYTLWPFWVDTHVTPPLKAQESGRSVKDRFGESFNFYNDVPAILDAAKSLGIKVGAASRTGTPHLARDMLKLLRISRESNGSTEKAIELFDYLQIFPGSKKTHFARIHDSSSISYDDMLFFDDESRNRDVESLGVVMWLVRDGVTTEEVDKGIESWRRRNKKVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9L9</accession>
    <name>A0A6A6P9L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rho GTPase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_377678</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9L9"/>
    <dbReference type="OrthoDB" id="437889at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07652">
        <property type="entry name" value="F-BAR_Rgd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000063">
        <property type="entry name" value="Rho GTPase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF136">
        <property type="entry name" value="RHO GTPASE ACTIVATOR (RGD1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="6">
        <location>
            <begin position="56"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="601"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="372"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="149"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="384"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="436"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="520"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="86079" checksum="C8FF80015CD76BA8" modified="2020-06-17" version="1">MASEVASPGGAELPGNDSFPGSAGPDGHTNCGAGHGPTLAEMPQPQTHIVDNSVSKAVDEVLYSDIGVSTLLNRLKQSIASARDFAAFLKKRSELEEHHAQGLKKLCRSTHDTLRRPDARHGSYAARFEDVTRVHERMADNGMQFALSLHQMHEDLSELSANMERGRKQWKQQGLAAEKKTQDAEALMEKAKAKYDGLADDYDRVRTGDKSAGRVFGIKGPKSAAQHEEDLLRKLQTADADYAAKVQSAQSLRQELVSTLRPQAIHAMQELIAECDSGLTLQLQKFATFNEKLLLGNGILVAPIKDAPAPSADADTAQPVSPSAATAPPSQQKSLREMVAEIDNERDFRAFVTEHLSKVPPRHADIKYEKHPTLAGPRAPPTAPSQSQPQLPAQQQHQQSVSTPQQTTGTTGSRQGRQSISGPPTLPPPSFGGGDSPQAPTAPQLPPFAQQQGGGFPQSPQQGPGGYPYPGGPNSYGPPPGGAQQRRRSESFGRPGGGAYGGASPPPGSGFGHAGYPPMSGGGAPQGDGRFGSQTQFQPQGPPGPPGPPQQQQLPQQSTSPTGGPGGPGALPHGNGLTMGGYEGPPAGAADLPPVRPVFGVSLDELFARDQTPVPMVVYQCIQAVDLFGLDVEGIYRVPGTASSIQMMKAMFDNGNIFLVLPPPYLIDASKVDFRNPSSFLHDVNSVAGLLKSFFRDLPDPLFTAQHYAAFIDAARIDDDAVRRDALHARINDLPDPNYATLRALVLHLNRVQEHQDRNRMSAANLAICWAPTLLGPHRGPLQDAGLQARVLDTILVNTYQIFDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9P5</accession>
    <name>A0A6A6P9P5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_316001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9P5"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="475"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="724"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="792"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="840"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="880"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="922"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="962"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="378"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="559"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="591"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1078" mass="118487" checksum="C3282FB4BB7D2464" modified="2020-06-17" version="1">MDGQHSLGSTAPQSAGVPRYSTIGQLSYGPTTQTTVVTTTFTTTTSFPPLVFNPPKHLHHRDPKQYPLASSPTPQSLKSLTFDVGGKPARFCEADDTEETVQKLNNEYESLRASNGLVSSVKSSGTAPDIFDSLPRSSLPPQNPSTSQTRKRPSSHISIAEAAEIAGSQRRPKKKRHSLRRTQFSSQESESATETISGSYFDGDERQLPETPDTDAGGQERLQPPQAKVSTRRADPRFARLRDSSSRHPSGTSEGLSGSLGMPRHSRRGACERDEDFVSDEQGYGGRRTGSTAFREPTAGMSATPPIAESDLEPAVSFTYEENERSSSGRPSQLDTVATQDASLPSPSLSPITAAANLANPSFANSLVASNEDEDVAELSSLDASQDRPDLRYHGRSASQALVPNRNTDLPTPVDGHSPNPQLPTPTLRDIPNMVDTFDAMPDELKTYVMYQMLRRCAKSTLHFVADVVNPALKCDFIGLLPLELSTNVIRYLDARSLCRAAQVSKKWREIINSDEKAWKDLLTQDGYQLPEGEIERAVREGWGWQYSDGVEGYEMDLSSTAPARPESAGSPSSPSAALAEKENTVSSSGRPKRKATTKYGSRKRMRKGAPSSASQTFVDISALDATKGPNTYAIMAARAIPYPELGLASLKSLHLFKTIYQRHHLIRKSWMRSETKPKHIAFRAHQRHVVTCLQFDSDKILTGSDDTNIHVYDTKTGALRTKLTGHEGGVWALQYEGNLLVSGSTDRSVRVWDIEKGKCLQVFQGHTSTVRCLVILKPTKVGENEDKTPIYMPKEPLIITGSRDSSLRVWRLPNANEPSIFQAGAPANDYDNPYFVRALTGHHHSVRAIAARADTLVSGSYDSSVRVWKISTGELQYRLQGHNQKVYSVVLDHERNRCISGSMDFIVKVWSLETGQCLFNLEGHQSLVGLLDLSDGRLVSAAADSTLRIWDPETGQCKSTLSAHTGAITCFQHDGQKVISGSDRTLKMWDIKTGECVKDLLTDLSGVWQVKFNDRRCVAAVQRKNLTYIEVLDFGASRDGVPIGDRGRRIVVDRHGKEIPDYDDSVDGDQDPETLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9V5</accession>
    <name>A0A6A6P9V5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_170917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9V5"/>
    <dbReference type="OrthoDB" id="5771378at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052729">
        <property type="entry name" value="Acyl/Acetyltrans_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041496">
        <property type="entry name" value="YitH/HolE_GNAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237:SF1">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18014">
        <property type="entry name" value="Acetyltransf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="35536" checksum="A841F3F960739165" modified="2020-06-17" version="1">MYVATSGTLKRLLRSSHPHLILTHSPCSHKNRSRLDAATYYRTLQPHPWFVVVPLDPSHDGKPVGCVVGYVHANGVGWIALLLVKAAYRGRGMGGALGEVVQTYLRQRGVQRIGLDALEHMTEKYGRRGFVETNSVTYVVRQGVKDVPAVFAEEDQVAKGLSVVGLDEVPRERLVESDRECSGLLRTTLWSPEGLFDREDVFGLALVGEQGGVGESLRGWVVVRQCHDGYRIGPLYAESKVEASTLVKETLKAIDKKDREGSVCAELFVGNRDALPVFEELEFNAVANYRRMWKQGDEPEEQRAGGKGRRCMFAGFDAAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Z3</accession>
    <name>A0A6A6P9Z3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA replication regulator SLD3-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_360865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Z3"/>
    <dbReference type="OrthoDB" id="5395343at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013948">
        <property type="entry name" value="DNA_replication_reg_Sld3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042511">
        <property type="entry name" value="Sld3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28067">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28067:SF1">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08639">
        <property type="entry name" value="Sld3_STD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication regulator Sld3 C-terminal" evidence="3">
        <location>
            <begin position="371"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication regulator Sld3 C-terminal" evidence="3">
        <location>
            <begin position="686"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="627"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="751"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="230"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="802" mass="90799" checksum="E87B07E8F2C24BC5" modified="2020-06-17" version="1">MSFSEPPKPLILEDPMREFRENFLQQLRESKEAEIAKMRSRIHKRPLEIKKREFSESFLQPFEYTATDQPESPPQTFTPHFIVLREDIPIQYRVRPKWVGCAYVARIIRSWIPVLEEEGTFGMQLIGRVDGKHANLVHVVDRLAEGSYQIRALRKHVKMHFFERLVNRQGIGHSLVSNGDVKRDFRGMGDYYAAKRKAFHDSWIPDTELRETQCVHLVDALDYEYRREMSAKLNREREIHREKLEKERRQYLAEEAAEEAEEAAKNERYKENGGGVRPFWLIQGLAIPGNTDDTVKFQTRQTPKVAMFRDSKILFGAMANVPQDNNLLNAKAPAPKDGPNTFDQKLPKDNSALDGNAPALDSEQLQLTSQEVFESFMTQYLDTLYISRTSLAFFAKGPLSRARAAFSKKENPSMQLSDLTAFLRDFIIPLPTMDKKYRDKVPTKLQDFPMVSYSDDEEAPPKKKVKTMKLKPTRDGMFPNEETYLKRWWLGGDEAGQVSRSEETADQARKRRAAGLRVRETLMQLILALEILAIEASPKYNSASGNKEAAKKRAKKPQDLKTTVDLIVDKLCIWQSVELEDVTAVESRLFGTKQTSLDKLATFCKEVIIPFFLSRLPGLAGGVNKKLGGPATSSSAPKRQTEELESSAKRRKPAPAAPSPAGKKPRPLQAAESLESIGVKKPVRRGNPAAEVGRLQRREMQMLAFAKNTDAKVRQKAEAGEALKSAIAMAKRPERREVGREWEEERVGRAKGVAAAKAPSKEAVQVAVTPAKKGRVKRRMEEVVGGEETVVDTPTKKVKTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAF0</accession>
    <name>A0A6A6PAF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_131170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAF0"/>
    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="67"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="165"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="27207" checksum="CE37758C6945DA0F" modified="2020-06-17" version="1">MSGKLDQSLDDILKDRRQSRPRRNRPARVAKTAATAPVGGIKKASKLAKQVSKTNVPTGPSSGSGEGKIIISNMPEDVDEKQINEYMKRTIGPVKRVQITYGPNGRSRGIVTVVFPQAHLVHEAMEKINGVRVDGRPLKVEVILGGNAIPPPAPAKSLTERISTGTTQNAKKAQPKPATAGPKPANAKDNKAGKKRQRGRNAGRGKPKSAAELDAEMADYFDAGTNGNTTGGDAPMGNGNGGAQAATNGSEAIMSDEIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAG7</accession>
    <name>A0A6A6PAG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_369035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAG7"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050308">
        <property type="term" value="F:sugar-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07527">
        <property type="entry name" value="HAD_ScGPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.240:FF:000013">
        <property type="entry name" value="Glycerol-3-phosphate phosphatase (GppA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051806">
        <property type="entry name" value="HAD-like_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481">
        <property type="entry name" value="FRUCTOSE-1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481:SF4">
        <property type="entry name" value="GLYCEROL-1-PHOSPHATE PHOSPHOHYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01135">
        <property type="entry name" value="C1.5.6:_HAD__Beta-PGM__Phospha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="242" mass="26309" checksum="21122AE1D461B3AD" modified="2020-06-17" version="1">MPHIQDAKFTAPLEVHRFHGLLFDMDGTVIDSTDAIVKHWHKIGKELGVDPNVILATSHGRRSIDVLELYDPKLANTEYVSYMEGLIPKQFGADAVEIPGSRALLHQLETVGAPWAIVTSGTRPLVMGWLDVMALAHPRNLVTAEDVQRGKPDPACYLLGREKLNLPAGADSVLVLEDAPAGVRAGKAAGFKVVALATTHSVEALVEAGPDWVVRDMRSVTMKGWDQKTGEVSIEIVEALQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAH5</accession>
    <name>A0A6A6PAH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_278982</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAH5"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11059">
        <property type="entry name" value="CYP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF164">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="59326" checksum="7584BDC62263F014" modified="2020-06-17" version="1">MSSTSIFICLCISALLAGIHWLVLEPLVWSHTSQIPGPKLFAITKWRLAYEDWKGSRTRTINALHEKYGPVVRIGPNEVSFNSLTALRTIYGTGSGFERTSFYRMFDVYGKQNLFTFGTAKEHSERKKMIAHAYSKSVMIKGPAADLVRRKVAAFLEFLENDKERANEIFSSLHYFALDSISEFVYGDMGRTDALGKSEADRTLIRDILDPARRRLSWFSVHFPGSTKWLYTRTKFMERLVTPFLPMQKPTYSGIRDFALKVWQTFLSAPESDKVRPSMQNSVMGTLWKHHSSQKAGGLQDLDIASECADHLLAGIDTTSDTLMFLIWALSRPENSCFQKKLADEVSTIPMCSVDDRGVPSVDVCERLVYLHAVIKETLRLYAPLPASEPRSSPRDTVIDAFKIPARTVVSMSPYSLHRNAEIFENALRFDPERWLGESAKVPEMKKWWWAFSSGGRMCIGMHLAMAEMTTLVATVYRNYVTSIRQGFEGITPGITSRFEVFYDASVPEMKEHTCLISFSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAN3</accession>
    <name>A0A6A6PAN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_383665</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001638">
        <property type="entry name" value="NACHT and WD40 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031359">
        <property type="entry name" value="NACHT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17100">
        <property type="entry name" value="NACHT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="8">
        <location>
            <begin position="361"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="857"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="899"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="941"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="983"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="1090"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="1113"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="1151"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1284" mass="142266" checksum="68893E676B2246BE" modified="2020-06-17" version="1">MPFKRLKAKFGKKDPPTSPRVEALPTSTTPHARTAPDPATFPPGLPARLWNQAYDQAKTSDSSTVDEYEKILSARLSQQDADASNPPHSADLASQQNEIAQDADKRRMQMQQLVKQGMEDGIQAAMAVKDVVDKAIQASPEAAVAWVGVCFALEILMNPLTQASSNRQGIAYVVSRTDWYWNLSSLLLDENIKEAHSPGLRDELEKVVAQLYAKLLLYQMKSVCYYHRGRLSVFARDLIKLDNWDGELSDIQAAEAAVQADSAQYNTLSIRTQLGAIAETAKSQNAKLDSISSAIREQTKQQERMHEISADNKCLKDLHLTDPRDDKKRIEETKGGLLKDAYRWILDNADFRQWRDNPQNQLLWVKANPGKGKTMLLCGIIDELQYSMDATDLLSYFFCQATDSRIRSAVAVLRGLLYLLVSQQPSLISHVRRKYDHAGKTLFEDANAWVALTEIFTSILQDPSLKCTYLVVDALDECITDLPKLLEFVAQQSSTFSCVKWIVSSRNWQDIEERLDKVRHKVKLSLELNAQSVSSAVTVFIRHKVLQLAGLKTYDDKTRDTVLDHLFSNANDTFLWVALVCQSLGGVPRRNVIKKLNAFPPGLDSLYGRMMQQISNSDDASLCKQILALATIAYQPTTLEELPTLVEQLEDVADDPKSIREIIGLCGSFLTLRKDTIYFVHQSAKDFLSTKASHDIFPSGIEDAHYVILSRSLQAMSTLHRDMYSLGKLGYPADQIIQPNSNPLAALRYSCIYWIDHLCDWSLSASADFSVALQDGGAVHEFVRKKYLYWLEALSLCKSMSKGVVSIAKLETLTYASALLFSPTGSLIREHFKDEELQWITIKPSIGDQWSACLQTLEGHSDSVMSVAFSHDSARLASASFDKTIKLWDANSGECLQTLKGHSDWVNSVAFTHNLARLASASSDYTVKLWDANSGECLYTLKGHSHWAKSIAFSHDSARLASASSDKTVKLWDTNSGECLQTRKQHSDTVHFVAFSHDSARLASMSTDSTVKIWDTNSGECLQTLEGHSNSVQSVAFSYNSAQLTSVGECLQTLIEHSDWVSSVAFSYNSARLASAGECLQTLIGHSYTLASTSTDSTVKIWDTNSGECLSTLEGHSDMVHFVTFSHDSARLAMTSTDSTVKIWDTNSGDSVAFSHDSAWLASASYDCTVKLWDANSGECLQILSIGKTLRRISFDITAPYLHTDIGNIKICVPPGLPSPLPSNTEPQNPQYQGLALSADGVWITYSSENLVWLPSEYRPVCSAVSGKTIGVGVGSGRVWMCNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAW7</accession>
    <name>A0A6A6PAW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mus7/MMS22 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2386201at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035361">
        <property type="term" value="C:Cul8-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019021">
        <property type="entry name" value="Mms22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09462">
        <property type="entry name" value="Mus7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2133" mass="240146" checksum="B245413E9BC24644" modified="2020-06-17" version="1">MKVSGWRKRPNWRELGVVQDSEDEEELDVHSTNSEGVKDAHDSTFEDVQIPAQSANDSFASGESERPKYPCSLVPVFIDPRFQKPHAPDEDQESQTAAQTVSPTTPTVDDSIYLNVGSNNEAASPLPISENELLVEDGTVVLAIEPGTRRSLRQRKAIQLHPYLIENEKYRRDLRARGIRPITLQRQTHREPSPEYATDSERSSQSQNVASASLAAPEPPKSSPPLSDLLETLSPSEGGHMQARPTEDDEELPDLASLLSSRPQKFVKNGSKRRRTERTYIAKRPGPVGRIAESPQSKHRKHQSPITGVFPEGNFDILSPAMSTPTFPINEQFVQPAVGGIGPSSVILPTPATSSEANRPNAEVVETPEPPQASSTKRRIFSVLSSSDVDSPPPAHCSPSMDLTESTSGSGEDEQELQRVKRRMRGVLPASWLKLDQQTRENGGKSRFAATREKSAETSFPQPGLARKVQRRRDLERSHSPHLFDQDLERISNGPGLSPQRSISEIHLTPSPEEQVSNSGINGFDVGRRHMNPLLDLTSQSPPQATRDPAVKSFRIRQSKLKPVVGNLGTSNRRRWTRDIYLDRNDSASTSRQPFRRTTSEISEGATSSDQFSPDNTGGLVSDRSTPENDKDDLVCGYELSPVSIAGSDSFIGSSFRDPSRYASCSPTSSSRRPVRSRVSNSAGVSDVPSANNLTSLYGCRTKRQPKRPKVRQTRLNPMVKSFHDHNPNRHGTSGGYKTISKKPAESFTRAGNRELRDGQLEFPETEFDTNHRKTAFRRDLARIDTLSREGNYHDPFIGDTGSPNENPVSWSTTTRDITKPRVPPSKAFSRNVEPPAHSAPKRHAKRPSDPNASRTYRPQSNHLDHTISVADIHTNNCPAPFNEVDNFVPFALEYSSSFDIFPLDPETHFHQDSFIGSGRLHDAFTERDLDALPSFMNITIRGKAYRWGPWTDEVCSEMAEIFQIVMDSVQGTIASDPSVLGSRGSESYLSLNVALNYIASYLTFLDPIDRTSFVLSFGRLLRETGGRILGFAVGSHSQYQLRIALSLTVLSCQVLSISKHPCVDNEKRKNVEALLMDLARFLVASLNYCGFHDMRSFLHGNRSRYNGYTTIRPSNFAIDGVVTLACILQHAAVPQGSIMDLQAEIQLSLVRDATEVRQFERVWHDTFVVLPFLEIDTHGRVDVGRRFRITAENWDAIREILDRLFKFHDNQRNRRDYGLNGYIRACFSRCHRLIDNWGWHSCYGVMKTIFDFFARNRLAPLRNEESRGSPDFLDSLHRDPAVAVLAGDRAFHIFLKILASSLRASRQKLPEKQITRLVWRFIPNHGRYHPRDQDMRQVDLDAFRNHHDLLATLFWASPPPCRPRLSLFRDLVDHISSHREVCRLNIRTWTSLAKFLVSEGEGDSSLQPLADWFRDIVFGTIAQFRQARTEAEHQFEISKGQNGAQVSQTVLEAVINGNQRPALASLADALRGLGNVLKVAKRTESSTFLLENSNMVQSFKLFDGRANTATSVILEALGAISDAIDRLTRTPTESRSLKIVQDEDSQDYGEWPDITDLEFPGEEPSSPSVGMMFLHDPLYSLLSNCFGAESAPEDRLLIKSVDVWSHFAGHLINVKSKKWTDFVDPFSPSSWHELRETEHKRKYTPYFIAAMLEADVELHEGFTTFVLTSWLISLVERESLLKFQHKLTTAVLNAYPSHPILQNLPFTKDENAARYDISANDVHNRRLMTISTILSNMRRSIEGVASEKPRRLSERREQYRSLLRSLMSKMKENFGELQQHSAAQGTYVGFVQTVVQFMQQYTADICAVDKFFTDSAAFPLPADDPTYVVGKLKSYELKLQDSRSAKQLMVYLQNLSERAAIDNQQKYLVRQLHAAMVDPTGGSEFGRHALREVFLQSVLPSYAELCIESPAGWIFALPMLQASACIFDELKYDLDVANHSSVQAWLLSITVTLDVLRRAAELLIDHPGLLEQSSVLRVLWLIFEIVRAVAMPLDFFRLRNIQSEEAAQRVEFFRSFSLFAAEIVLGHGDALAPSTYGDFDNVETPYESLRQYCTQELRQAARENWVKRGDNYFVRRGNMDRRVEVDLDQSEEEQRRLIAKIEEFHGVLGQTFTFGGSVPGRFSELPLGDLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB73</accession>
    <name>A0A6A6PB73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E3 UFM1-protein ligase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_170935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB73"/>
    <dbReference type="OrthoDB" id="3935714at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056761">
        <property type="entry name" value="Ufl1-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25041">
        <property type="entry name" value="UFL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E3 UFM1-protein ligase-like C-terminal" evidence="1">
        <location>
            <begin position="579"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="659" mass="75603" checksum="28A70F9F704E0A33" modified="2020-06-17" version="1">MEDMFSPIDLQEIFSTFPPTSRDLTPNTSQNAFVKTSWIPQYLEEKLSSSDGRLRLSELAREISLPTISISIYLHRLSPPILRGQDPDIVLSRSEEDSIIQRINEQLNRTVRSHASVARQYNLNENSLRARVAPELDTDGRFNYYMRNFRGDPADYFIKENFIETLKAFIANTMVEAHEIATPKTLSYHTEDPESEVFKELVLLVAKELQAEKEEFKGYGSVEEMDTEFPRFVPKTYLEKELNSLFDKLGSGEMVFCTVNYLKSTFDDLFRTPEEDIWDYLSSRAKDTIFLGDSIVSRAWFDNAVEECRVEVAEKGFANLANLLDPIPEDWKQRVFEVIGHKIEEFLGTDADTTGIEEIYPFFTRKDQFNQAPQRLFDATIQQAHEQWDQAPPKTSTECTINIEQIMESVANTLNLPMAIVQQVSTQELETGIKSCFRKQISELEAEADTQLAIFWRDRVLLRLRLYEQGLTTIDAEPKLQTQLKELLFTYVTKDMIPDHINKVAAKRLLRSATARKQTEKLRAGVKECSKTRNGDVSVDLQALHKLHDHFAAKLHVKAPNEADLVEGKESLIHDMIRSMNSDTDAPKLFLTLMVVLLSKRHDGLVYATGQFVPKLLKVLKKSMDNEKYERLDALKEAVKAGSLQSDAWAEMKKIAEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB76</accession>
    <name>A0A6A6PB76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_136724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB76"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="619" mass="65343" checksum="138D76D8DF18B182" modified="2020-06-17" version="1">MRTNQNQANLSKKKKNPIGTRKLRCSGDYPRCARCARESVECVYSPQKKMGRPRKRAREAEDDEPATGAGVPQTGWPPPPPPPSSQSHSASSSSTAVPTAVQAFFAPDRRASSSNTSAASDGLNGHHGAAQRRRHSQHHQQHHQQQSRQQPVVMDLGAESAVAAVAAAGIEEGHLLDSLAPADLSAYDNGIVGTDDYGGSGGPGGGGGGSFGALLEDMGVHGYLGIMNAGPASNGDGPMNSFDLGVGMAMASGMEELGFGAQQEHHQHQQHQNHHQNGHAFDAGFSHDGNQALFGFNQTFSPASFLAPYITHDTQHAGAHQTIPEEPTLGHLPTTTPGAVVATPAASPSSSSQPHSCMSTMSQSAAAITAHSRRPFPFSLGPLRDGRRAALAMLDCPLCPTSPMSATQNVYLLGALFAMLAERYRSEAAAIEAEAERASAQGTRKRFLLGDMSREAVEHGWHTGSVDCPARFSVELDAAEWRKLAKKVIKEEVLGAEGGNAAAAAAATENGNGAPNCSSNGNGNGHLAVEEVDEVVSSTAATAAAVAGGYHGHTVPSVVELLQRAEDRQERWHADEAMNAMRARLFPGIQQHMGEEHGGHLCFTVFHRIRKNIQAMDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBF4</accession>
    <name>A0A6A6PBF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane amino acid transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_331735</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBF4"/>
    <dbReference type="OrthoDB" id="28208at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="252"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="64"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="655" mass="69963" checksum="A238FEB9497A6424" modified="2020-06-17" version="1">MARHDPRTPLSAAQTQRAEEASSLLHDRRDGPGAFDIDLDTDSSASSDIVVHARADNSADDAAHQQQPLPPATTASPAPRTPSALNVLPSRLTPSPTPSPGQSSGRPTPSGSPSPPGAAGGPPQPKRQSSFAQPRPGGTPRTPNRVRFDVAATSGRGSEEARMGEDEDDRWVDEEDWMEERGRREGGVGLGLTGLGGRRGARGRSRDAQGRREPGEQHLPLLTGIEAPSVTVAGGADEGFEAEDLLESSRPKSGMRSAFMNMANSIIGAGIIGQPYAFRQAGLLTGVVLLIGLTIVVDWTIRLIVTNSKMSGTNSFQATVEHCFGKSGLIAISIAQWAFAFGGMVAFCIIVGDTIPRVLAAIFPSLANMSFLWLLTDRKAVIVLLILGISYPLSLYRDIAKLAKASTLALISMLIIIITVVTQGFGVPTEERGRIQGSLVMNAGIFQAIGVISFAFVCHHNSLLIYGSLQKPTMDRFARVTHYSTGVSMVACLIMALSGFLTFGDKTQGNVLNNFPLDNIMVNIARLCFGLNMLTTLPLECFVCREVMNNYWFPGEPHNPHLHLIFTTALVISAMTLSLLTCDLGAVFELIGATSASALAYVLPPLCFLRLRKTKDWRTWVAWAVITFGGLVMALSVVGATIKMTKNEGGAQTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM1</accession>
    <name>A0A6A6PBM1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_140692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="20514" checksum="2B4D36A0AD8E269F" modified="2020-06-17" version="1">MEVDRRRLQLASSCSSLRAFGAGEGSRQRAGAPARAPGDGNKSPERGEMRDEARRESLARVMDERRWQPEVAAERRRGVRSAAVEVVCVGARCRAEADGRVLRARQRSEGFSVAWARKGSRQQVAASGAAGGGVEKRLARLMMRGAQLHQSAHTQTAWGVQVPAGRVNHKAGAAHGRGRAWLLGSPLDACG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBX8</accession>
    <name>A0A6A6PBX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_135441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBX8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025387673" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13619" checksum="D867F8B2D6D2A89D" modified="2020-06-17" version="1">MTVGSSLVALSFRSFLLALYSPSYLAACERLQGRLSCSRICVFPWTSAPGWALIFTRGRRRRVDQEPSTPYIRSMYIACDVEISRAPPWRFAKPQAKAKWPAEKQRTKVWCHRLIVVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCF4</accession>
    <name>A0A6A6PCF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_376504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCF4"/>
    <dbReference type="OrthoDB" id="5339776at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025040">
        <property type="entry name" value="DUF3984"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13136">
        <property type="entry name" value="DUF3984"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="492" mass="50814" checksum="27A0BCA45B0FD339" modified="2020-06-17" version="1">MEVSSPPSFYSTRSSRRSFPNLHHLSLAPLSSRFPIDDAADDDGSGSQHSGSGGGDPSFPRSSYIANASAPTTPSILGRSPSRRRLHSNKGVSSKHGGHRAMYYYSGHAPGLRPDAADLAPGDITKAKSSSALLGGSSALGPLPHGARTGTLTPAGSSAKRRSAGYLGPSAGGRDTGADEWLHRAGLAIAAEARESKGQAWLVSRASSTSLVRSSEDNDDSDSAEADGLDDEGAAGRRGGRLGSDDDRFRLRLRRASLASSDPFDDTADELGAAAPAAHAAAGRTPRRSGSRLASAPASRWASRHGSRVGGSRPDLHGAGGWRTPRTGGALGEETGGGGYFGDDVVLAAEPDFVEGDPDEDEAAIEDEAEVARLAGESGAFGLGGWVDRLIGWSLFSVDEDAEGSDVEEGEGTAAGAAAAAATTVSQAEEEGKKRRGEEAARRREDLERITASIVTGEHHGEPAVEVQEPAQEEGGWHDAAWLLSVASKVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCH0</accession>
    <name>A0A6A6PCH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_360710</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="3"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCH0"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004760">
        <property type="term" value="F:L-serine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019265">
        <property type="term" value="P:glycine biosynthetic process, by transamination of glyoxylate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000049">
        <property type="entry name" value="Alanine-glyoxylate aminotransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000027">
        <property type="entry name" value="Serine--pyruvate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF24">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="11">
        <location>
            <begin position="23"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="385" mass="41521" checksum="BBADDD2873B5CD2D" modified="2020-06-17" version="1">MSGQAPHPALMIPGPIEFDDAVLQAMSHYSESHVGAPFVATFGETLSLLRKLFQTTNPASQPFVISGSGTLGWDQVAANLTEPGEEALVLHTGYFGDSFADCFETYSVRATQLKAPIGDRPQLPEIEAALSEKKYAVVTVTHVDTSTGVLSELPDLARMVRRVSPDTLIVVDGVCSVGCEEIAFDEWDLDVVLTASQKAVGVPAGLSILMASGRAMEKFKARKTPPTSYFASWKNWLPIMQNYEAKKPSYFATPSPQLIHALHTSLAQILARPLATRFAEHKAASRKIKDAVQALGLRQLAEKPENQANGMTAIYLPDGLTPPEVLPNLLKKGVIFAGGLHKEIATKYVRFGHMGVSVTDPARNDVDKAVAALREALGEVGYKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCQ8</accession>
    <name>A0A6A6PCQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_333132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCQ8"/>
    <dbReference type="OrthoDB" id="5425782at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025398856" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="33754" checksum="8FD7898D68B55F60" modified="2020-06-17" version="1">MRLRLSRGALSLLAILALLALVSQAEADPRGIHHPRQAVGTGTSATQTDVNSDVVSTTDDSSATPTASDDTGDDTNTSATPTDDGGDTSATPTDDPVTSSPTPTPSQTGGNDDDNDDDNNDNNDDNNDNDDDNAESGSSSPAGASSTPPPSTTSSSNDDDDNSAATTLSSVTRATTITTPLVTSRTRSYTTTIVTVDASGNAVTRTSTSASVVAETTGFATVTQTPSLGSSDGDDDGSSGLSESSKRIIGGVVGGVGGAILIGGVAIVLWRLYGRKNRAAKAAADDDDDVLSGTTAAGGADSMRTEKRGSAQPFQSTLDQYHNPGGRNVNAASNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDM4</accession>
    <name>A0A6A6PDM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_329865</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF3">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE AN0832-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="16">
        <location>
            <begin position="35"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="505"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="697"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="814"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="905"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="962"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1211"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1293"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="905"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="940"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="986"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1007"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="1047"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1211"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1241"/>
            <end position="1258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2461869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1318" mass="147155" checksum="0C4472C375566960" modified="2020-06-17" version="1">MALHSLDAAELSERLQWAHQDYWIHIDADSPLEKYPAKQHARAVAQALGIDHGLIYLAGSPSRLLEDSDMPQPFRQRRYFYYMSGCDEPDCHLTYDIAADEVDLFIPKVNPETVVWVGRGLTMEDAYQRYDISLVRFSDELEKYIEKWLYFHPGNVYLLHPKQNAGLDVGSHRVIVNQLQHAMDLARVTKCPHEVKLIRKANEVTGNAHRQVLMNVKKFRNEAQVEGIFLDTCVAAGAKDQAYEVIAGSGPNAATLHYVKNDQDFADRQLMCLDAGCEWECYASDVTRTFPLSGLWDGLSEAKAIYDTVHEIQTACIERIKPGVRFLDLFIMAHEMVTKALLKLGVLKDGTVDEIMQAGTSRAFFPHGLGHHLGLDCHDVLGVTSLVCGEEDEKHFQIQREEYAALFEESATQASYYLTLGGLSGSLAEGMVVTVEPGIYFNRFALDTMYLSEPKHANYIDKEVLERFYPVGGVRIEDDILVTKDGYENLTTAPKGEEMMKLLRGEEEEEPKPRSVPRQKQNQAQNKGREQKSENGSTHHEKPNQTDPLPKTPARALFEGFPNAATVQNSAPNPPNERRIFYDGCVNCNKRDVSCVGERRENRPCSNCQDRSELCIRVPCPGSSHAPAVAEGMWQLRQRAIARREDAAKREDAAKACRGIEKDTWAKWGSYEANKSPWAATVGELERLNHSLRAKLAKNTDADSNSSRSRLPPGATEAGPVASGFWQRVKNEEDGQEGVDGTQAARVNATLARNQRSVELLREDARLKKEVQLKLEERQQKLLKRQASMRFPERDPQERRLVLPWEKWGPQAFAQEQAQPHSGPQPSQLPSKLTPQPLTATQQLWTRPWDSQQPLYPTLGRSKSVHFNTQPTVIGSAAICSSSQQGQSEQQYRNFGSLLASPLSYQPQQQRPLGRSQTVLTPSANRNRTEARATARASGEWSNRQAAPSSFDSGYDHLLCDNANGSDKSGNGDIATNARTRDTDRPPAPPPKTPPLPAKPPAYRPSVADRRKAALEKLKEAAEVASAAARPERLNKTTSLETGPASGIPPAPAPQRRPPPPPPKENMHEGPHGSISNWYGRGLAPQQVSEHNRRLRYHASMPSVGQHFRESEQLRPGSPFAKPIRSVAWMLPMERNDPSEVSEADIREGRDRVSAWLAQGGKEGPFGEAAQAAERLPEMALGAQHEEQPVREDVQRAADNARRWWATEKVMKAREEAEREEEKARKERFEMRRTMLQGGSKEGEREKLDSDRDKKAEDGSPGPLERMQLPVLNEELQRGLAAMTFDEPVRLGGAVEGSFGRSSPVVGSEWQGGLSSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEA9</accession>
    <name>A0A6A6PEA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_11276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEA9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="21449" checksum="7C90598FD6A31D51" modified="2020-06-17" version="1">MQIHYATHTTKSTAATTKSPPSASWQNFGANKNSFNGASRPRSNIPRLQPHRTVLSVAFTHSLSTSTEHPAIPPISPIAPTQHPPTTQVREYRGQKATTLTKESRESNDRGMANPRSNKTQASAAQRNRSDVCKKRTVPMLKQESADGPKKKKKKKKKKKKKKKKKKKKKKQPDQVRITGRTVRRTRHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED4</accession>
    <name>A0A6A6PED4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM3</name>
        <name evidence="11" type="ORF">BDY21DRAFT_383155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED4"/>
    <dbReference type="OrthoDB" id="29543at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000036">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="14"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2462127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="11015" checksum="45039C2210387C6C" modified="2020-06-17" version="1">MADVEDSGASAANEPLDLVRLCLDETVFVKLRGDRELKGRLHGYDSHCNLVLGDVEETVYVVEEDEDEPSSEAVRTVKKHSEMLFVRGDSVVLISPQPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEQ5</accession>
    <name>A0A6A6PEQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_329914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEQ5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025380910" evidence="1">
        <location>
            <begin position="26"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="132" mass="14376" checksum="A568C55E130C8685" modified="2020-06-17" version="1">MKTSIVATLVYSCLAVSTLPKYLGAQDTPLDLPPFTEFQAQAAYTCTFDDAVDLAPTLIVILETLFPSETADCDGVSLANCIEVGNLAMELDPVFRRAVVKRQTDSLECKLPHTPYLTQTIAQDTCCTSSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFE8</accession>
    <name>A0A6A6PFE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_360355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFE8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="11894" checksum="6CA0ECFAC25A6F19" modified="2020-06-17" version="1">MPWPDPLGVLPHSLLSLQRAVISLARATGTTREIPRSPLLAGPPSSRALQQQHDTLVASTRNKHLPYDALFDEPERGLSLLLRVPQAANNEPFGPRWAMQAMPPVSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL29</accession>
    <name>A0A6A6NL29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cornichon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_294838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL29"/>
    <dbReference type="OrthoDB" id="434393at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="16163" checksum="0B4FAA6E04679681" modified="2020-06-17" version="1">MSGEAWLYLLAVLINAVNLFLQVFFTIMYSDLECDYINPIDLCNRLNTYIIPEAAVHAFLTVLFLLNGYWMALLLNLPLLAWNAKKILDNQHLLDATEIFRKLNVHKKESFIKLGFHLVMFFFYLYSMIVALIRDESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLE6</accession>
    <name>A0A6A6NLE6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enolase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_294557</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLE6"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="15">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="14">
        <location>
            <begin position="143"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="375"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2452478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="439" mass="46890" checksum="FE7351C6AEE93ED9" modified="2020-06-17" version="1">MAITKIHARSVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSNEACELRDADKSKWGGKGVTKAVANVNDVIAPALIKENLDVKDQSAVDGFLNKLDGTPNKTSLGANAILGVSMAVAKAAAAEKGVPLYAHISDLAGTKKPYVLPVPFMNVLNGGSHAGGSLAFQEFMIVPSGAPSFSEAMRMGSEVYQKLKALAKKKYGQSAGNVGDEGGVAPDIQTAEEALDLITEAIDSAGYTGIVKIAMDTASSEFYKSDTKKYDLDFKNPDSDPSKWLTYEQLADMFKSLSAKYPIVSLEDPFGEDDWEAWSYFFKTAGDFQIVGDDLTVTNPIFIKKAIDTKACNALLLKVNQIGTITEAIQAAKDAFSASWGVMVSHRSGETEDVTIADIVVGLRTGQIKTGAPARSERLAKLNQILRIEEELGDKAIYAGENFRTAVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM77</accession>
    <name>A0A6A6NM77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM77"/>
    <dbReference type="OrthoDB" id="70823at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="7322" checksum="D6F82125398D337F" modified="2020-06-17" version="1">MRAVVGEGGALVAPTGRLGLVAAAAPLGIKASGGVRTLADVRALVEEGATRIGTSSGVAIMKEAEGEGAGGGGGGGSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMK5</accession>
    <name>A0A6A6NMK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_294281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMK5"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000035">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="14"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19616" checksum="668A0C8FA2841B7F" modified="2020-06-17" version="1">MASPAPANENPIVFFDITLGGEPLGRVKMELFADVTPRTAENFRRFCTGETKNPQGRPQGYKGSKFHRVIKDFMIQGGDFLNGDGTGSTCIYGTRSFADENFLLKHDTPGLLSMANSGKDTNGCQFFVTTVPTPYLNNKHVVFGKVVDGMDVVRKVENVRTTREKPNMDVVIAQCGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMK6</accession>
    <name>A0A6A6NMK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Basic proline-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMK6"/>
    <dbReference type="OrthoDB" id="5400063at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="45857" checksum="6436A216C7813817" modified="2020-06-17" version="1">MTSPVLSTSPSSSSSSASTVLPLVAPEHPANTSEPHPSCNPSGSNSPPKPAPNSFEDHETAISAPVPTTPLPTEHITVMAASTVDSAAAEPTEQRQARPMTPRASSDPTSASTGSSGSSGSELAVFSSPATSPLQLGEPRNRSPYSRNGHFRSHSSSGATGAPPMARANSLPTMPTSMSQLSLSTSPSPSLIASSDSPFMRPVSPLRSPARVGRSPFRTSFDDLPVPGGPGGPPSRGSEIGSISEEDVLDLTPKHQKQAAERGSLQNTSSLSALPSLHHSNSFPRRRRPASPLHQMSSASIPGQPSQQQQQASSTHSSPLLSATRFNEPFPHYAVSLSSTSSVPSTPTSMRSRSPSISSLETIPDSPDAEEAAIEADRIARLKAAAEHENSSSRSNSLEVPSGRGGAFGGGFGGRDKRKRWSVCGAERRGDLDLETIWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMN2</accession>
    <name>A0A6A6NMN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ADP-ribosylation factor family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_388319</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMN2"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000832">
        <property type="entry name" value="ADP-ribosylation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="184" mass="20933" checksum="886CBE0A86F3C8DF" modified="2020-06-17" version="1">MGGQISKMMNKIFGSKEMRLLMLGLDAAGKTTILYKLKLDQDVTTIPTVGFNVETVTYKNTKFNVWDVGGQDKIRPLWRHYFSGTQGLIFVVDSKDRDRIDEARTELARIIQDREMKDALLLVFANKQDLSDAMRPNEIKEKLQLDRIARDHVWKVEPSCATTGEGIFEGLAWLSSNVKQPLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW9</accession>
    <name>A0A6A6NMW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_367302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW9"/>
    <dbReference type="OrthoDB" id="274828at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="102" mass="11010" checksum="8FD1927F942895A3" modified="2020-06-17" version="1">MVPTVVKPLRRVGCANPYNGINGSNTLSAALKRRIATLIATLSLQSACELGARDPDFAWPVFRAFWAELTKPGLGRPPVMTSRQIPSIFATDCRSSAGNTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN11</accession>
    <name>A0A6A6NN11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_367297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN11"/>
    <dbReference type="OrthoDB" id="5150140at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="15653" checksum="74F513953A6FA9C4" modified="2020-06-17" version="1">MRRDDREIDYYGVFFAHLVPENEADPEVWTAYIIEMEKDGGKYARQHLHVQVNPEDCFESNVLPEETGNDGSGQNQFRGRMAHLKRKEASAVRRVTGELVLYFEKVEGLVGKGDNVLPNRNMLPSISTLCLDDSEDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP82</accession>
    <name>A0A6A6NP82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP82"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="23392" checksum="E2C5EC748129AE57" modified="2020-06-17" version="1">MPALPPHAPRTPPRQPRSNTPRLLAPRQYRPRVRRRSSTRSPRKRARARNTMVPRVELRRPQRQRNARAQARPLRERLRRGDIDPSPNCPPRQPRGRRGAAARPPRRVHRPPARNTRSCRANLPPLPDPALRPATPPITRPSPTPTMRHLLTSAITPPSRSTRTGACRRRRRGPHPLISTPTASPGRPRLAATAPMTCWPGRVRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPQ2</accession>
    <name>A0A6A6NPQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="10">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_327130</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="10"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPQ2"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="231"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="487"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="85"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2453765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="771" mass="85655" checksum="D4AF286027EE1F17" modified="2020-06-17" version="1">MAPTHDTTSKKRPRPPHRTAMKPGKQQKLASRTANSSSKAEILSPGRNVRPDDLSWTEVSVQGRLDDFEGFFGLEEASGVDIVKDPEGGKVAFRQVAPSHEKAKAQGKSSQSEELPTSNISQSEEPMVLEQDPVQHEEELSDEEEWEGFSDNNAVDCGSKTSKSNGSHKMKAKDDLGFISRNLSFDVLLRDSDDEEIDMSAWNELNLSNETLSSLSKLKFARPTPIQSTAILEILSGHDTIGKAATGSGKTLAYGIPLLEFYLQETRLRQRPNSISVDKPPPLALIMSPTRELAHQITAHLSALFSNAGFVGPSLATLTGGLSVQKQQRLLKNANVIIGTPGRLWEVLSQDRDIIAWLQKVKYLVIDEADRLLSDGHFKEFDEIINALDRVTENDEDEEAVENKQSLIRQTLVFSATLHKDMHQRLAGKWKPRNELPSKKESLEYLLARLKFRESKPKFIDINPVKQMAQGLREGIIECGGIEKDLYLYALLLYYPNARTLVFTNSISAVRRLVPYLQNLNLRTHALHSHMPQKARLRSIERFSSQPGSILVATDVAARGLDIPNVELVLHYHLPRAADMYIHRSGRTARVENIGTSIILCSPEEVVGVRRLVAKVHASHSEGSSKRSHFIQSLDMDRRVVAKLKPRVTLAKKIADTAIAKEKKNNDDDIFKAAAEDLGVDYDSEEMEKAAIGRRGRGIARRRSEREARNLSKSEVQALRAELRGLLSQKVNIGVSEKYLTGGGLDVDALLKGVANADFLGTMPGIQGFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPX4</accession>
    <name>A0A6A6NPX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_118909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPX4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="148" mass="17108" checksum="4EA6A85F4D02278D" modified="2020-06-17" version="1">MRQPSTPSRHKPPPSRPTSPASIHPNTSSTGPTLPAFVRPGVATVTWLPGRFAPESPPSTSNTLHLRDIHTGKKKQKRKRRKKRRNHTRVTKYFFSGCKQNKKKEKSKENTLPRQYQSPHHSRPSIRTSKKPQRRQKGQKKRNKIKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ92</accession>
    <name>A0A6A6NQ92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha and gamma adaptin binding protein p34-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_121383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ92"/>
    <dbReference type="OrthoDB" id="10261384at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034627">
        <property type="entry name" value="Irc6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28043">
        <property type="entry name" value="INCREASED RECOMBINATION CENTERS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28043:SF1">
        <property type="entry name" value="INCREASED RECOMBINATION CENTERS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10199">
        <property type="entry name" value="Adaptin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="36978" checksum="74A36BEA8916E3D4" modified="2020-06-17" version="1">MEIANPRRILFLGPPDSGILKLLEDLTGSAPDPLLIAPSSPTAPSSPRASATTSATAAATSADGPATSSPTSATPAPPPTSSIAGLSHTWVLRTPYYSATLPIWVDEVASAPSWRDDFLSPEASEVVRALGAWVYCFRKPVTGADMEGVRAGLRAVKAVLDEHGGGGGGWDGVCLAVAMPQSTAPRLAVEKEDWDEVCAECGFEFVDAEETERNRFGEVTGVARVREALEANDWTAEEDVGMDGLGELGEEEDGEESDEEFGKTFAAEEAEMSVELLGMKTAMRDEEFDGLGPPEDENEEARQVEELERMMVRMRAVKDMSEGMPDEERKRFAARAVNDIMKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQL4</accession>
    <name>A0A6A6NQL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="9">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_355427</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQL4"/>
    <dbReference type="OrthoDB" id="6425924at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="114" mass="12629" checksum="75FFA8DB31B54271" modified="2020-06-17" version="1">MTSTIGIPIKLLNEATGHVVTLEITTGQVYRGKLIEAEDNMNVQLKDITVTARDGRVSHLDQVYIRGSHVRYFIVPDMLRNAPMFRTRGARGRGVGLARGRATVNRARGQRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQP0</accession>
    <name>A0A6A6NQP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Transketolase</fullName>
            <ecNumber evidence="4 15">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_355557</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4 15"/>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQP0"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="16">
        <location>
            <begin position="356"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2453623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="684" mass="74814" checksum="D4C7F87B5C245446" modified="2020-06-17" version="1">MPYGELDQLAINTIRLLAVDATFNANSGHPGAPMGMAPIAHILFNKFMTFNPKNPDWVNRDRFVLSNGHGCMLQYALLHLFGYEVSMDALKHFRQVDSITPGHPEAHDTPGVEVTTGPLGQGFSNAVGLAVAQKHSAAVFNKDGYDLFTNYTYCFFGDGCAMEGIASEAASAAGHLQLGNLICVYDDNHISIDGDTACAFTEDVSKRFEAYGWHVIWVKEGDTDLDGMEKAIEECRKVTDKPSMIRLTTTIGFGSKLQGTHGVHGNPLKADDCKAVKAKFGFDPEKSFVVPQEVYDMYHKHAADGAAAEEEWNQLFEKYGESYPTEHADLKRRLTGVLPEGWQTKLPSYKPTDSAVASRKLSESVLEAIHEVIPELISGSADLTGSNNTRWKNAVDFQPPSTGLGDWSGRYMRYGVREHAMAAMMNGMASYGTVIPAGGTFLNFVSYASGAVRLSSLSHRRVIYVATHDSIGLGEDGPTHQPIETLAHFRALPNMMVWRPADGNECSAAYYMALTSKRTPSILALTRQNLPQLEGSTIEDAIKGGYVVLETPGAAVTLVSTGSEVAICLEAAKILKDQGKPARVVSMPCVEVFDAQPKDYRLTVIPDGVPSMSVEVMSTLGWEKYSHEQFGLNRFGASGPYKDVYKKFDFTPEGVVKRALATIDFYKDVKPLRSPVNRAFTNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQR4</accession>
    <name>A0A6A6NQR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_292467</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQR4"/>
    <dbReference type="OrthoDB" id="4215474at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF4">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="12">
        <location>
            <begin position="66"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="495" mass="55024" checksum="F0E82609F4CC6744" modified="2020-06-17" version="1">MRSPALRSPWRALWQRRRPHFRLALGPPSRRRQSTVHVPAAQLQFGQPIHETHPHLLGPGELTPGITAIEYARRRANLASKLPEGAIAILAAAETKYRSGAVFYPYHQDPDFFYLTGFKEPQALAVIEKTGPGGQHDFHLYVRPKDAKAELWDGARSGIQAAEDVFNADHAGDVAHANTTLADILSSGREVYTDLPGSFRPSAYAKYFGALSDLGSNGLAKLFERTRASSKPLRPILNELRSIKSEAEIQNMRLAGQRSGRAITDAMRKQFRSERELDAFLDYRFKMEGCDNIAYVPVIAGGQHSLTIHYVQNDDVLNVGDLVLVDAGGEYGGYITDITRTWPVSGKFTTEQRELYEVVLRVQRTCVALCRENAFLSLDKLHKIAEEGFRDGLTQLGFDVSRNEALTTLFPHHVGHHVGLDVHDSPGMPRSAALRPGNCITIEPGIYVPFDSRWPARFQGIGIRIEDSVCVGPEHAYVLTTEAVKEVVDIEALRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRD8</accession>
    <name>A0A6A6NRD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_423892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRD8"/>
    <dbReference type="OrthoDB" id="5403747at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="19726" checksum="90FED46A4C63058C" modified="2020-06-17" version="1">MPPKDSSMSERDMQVLALSWQCFTTQPNVDYEKLAALAGYKNKETASVILGGIRRKLLKLAPAPANGAAPGTPSKTAAAGTPGTARKRKAAGNKADDDYSPSKKAKAANGKGRGKKAGPTHTPTPETEVDDDEEHGAKETFHHELGIKMEEHVDDDAPGDEDPMFPLHPPQFNPDASFGPGGDNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP1</accession>
    <name>A0A6A6NRP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mak10 subunit, NatC N-terminal acetyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_103173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRP1"/>
    <dbReference type="OrthoDB" id="269405at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="5">
        <location>
            <begin position="38"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="6">
        <location>
            <begin position="326"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="654"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="755" mass="85403" checksum="E2429C6CE70B80AB" modified="2020-06-17" version="1">MPTSPSAPIASRRANASQPSCWDVTAPFFEAAKTLGTGTLVKDEFFTLFEAVGALEIMDPKMDSGFLAPGEDLEDYYDVTQPLSAQQVIGVVDQLLCYEMAWHQGYPLLQTLFTSHYIDVLLGSEPSDINQAVFSSQPDTSNDAGGRLVHLVLRAYCVATIKACDFVTQTVTSQNFFEEEDFSSHTYNRNLLVQVSEDHVVALLEEAEGWLEGEGGVSAIELRDVRLGLLSRIRLRKQFLIALCPGLSSEAQVNFNVIPEMLVGLEETHRFAEPVPTSFSQKIQRHLASTVPPRPIINLPFAEAVKKLSLLSKDAAEACRIQQYLKESPQELRNFLWAFNGRKPTPLAFPRAIPQTILFSMPREDWQLLYLKDLAGLVFPEDPVLDPVNWTIEASPRPGAPKHPGAVTAEIIDTFISQTMEGYYDLYTLPCQNRCRVRRMLRHVILFFDSLYNPCENLDTELQELHKDVVEFPLLTWINYQKLCLVEAMVQLGFELDIYLSDELAEMYWWLSRISAHRCGFLENLSAFARERQTRFLREKSIQKASSVEQTFLRLREMACEARSTELLAEAFSIMYMYLQYQHFIPTPRRPLSTAALRYELRMKPFLTVFPPGLPHFDQCYAELHPYGPYDENDFYPGGSDEEDHDKLPPEALRAEKNKLAQEAQRTIKEAKEQLSAVRKMGPGLGGAGCVAEQWEKNIADVLRACVGAGVALATVDKVVMTKGERVGKELSIEIPPSGERYHDWWIVPKVVVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ6</accession>
    <name>A0A6A6NRQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16663" checksum="043D1074B5103C80" modified="2020-06-17" version="1">MRPTRAGKPSSNLDNGAKKTSNQTSTSGTSNDHVHCANEEDQVPLDADNSAQASSNSDTLQELGTSATQLIRSVLRLLLKVVEEGENLEKICKITSAELAIVKGENSDLKTYMASLEQRRSRLQEQVKKKPRHYRPGTPVSCTITRDVRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS29</accession>
    <name>A0A6A6NS29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS29"/>
    <dbReference type="OrthoDB" id="285219at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="150" mass="14649" checksum="BC0DAB1E77AED8AC" modified="2020-06-17" version="1">MAEEPQPGNIQEGADDAPADLPTSAEGRKEAAALSSLEQRHDDDDDAAGAGAAARSKNVDTEALGKAMQNLDRGGGVGGAGAGAGAGDRTASSSAGAGAGAAAKKVKVDAADVGLLVDQLELSKVKATELLKAHDGDAVRAMTAFVTAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS37</accession>
    <name>A0A6A6NS37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_291591</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS37"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF21">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="33"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="510"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="59115" checksum="11A6FF60E64C14B2" modified="2020-06-17" version="1">MSTLGVRFLSAIVRNDAMKHDPPEIYGWRNFAIACSACLGGMLFGMDVGIIGGVLTLPAFVETYELDQKSDVERADLESNIVATLQGGCFFGSLFASWVADKLGRRMALIISAAVTIVGCIMQAAGEGILDVMFVGRFVAGLGVGAASMITPLYISENAPRAIRGGLTGIYQLFIVTGVMLAFWINYGSLQNFSGTATYVVPLSVQALPAILMLFSMMFCNESPRFLAKKDRWEDAQRTLERVRQLPASHDYIQEELSEIKAQLDHERMLISGSSVWDLQKEMWLIPGNRKRALISVGLMVCQQMTGVNAINYYAPLIFANLGITGTENGLFATGIYGITKMATCLCFLLFAADSLGRRRSLLWTSIAQGVVMYYIGLYVRIDPPIEGEPVPGAGYVALVCVYLFAGFFQFGWGPVCWIYASEIPSARLRSQNVALAAATQWLFNFVVAKATPVMLETVGSHGYGAYLIYGSFCFSMFFFAWFFIPETKGISLEKMDELFGVTEIGSAKDEEAGGVRPAGSSADGADSKDAAVERVEEHKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS68</accession>
    <name>A0A6A6NS68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase III subunit RPC3</fullName>
            <shortName evidence="8">RNA polymerase III subunit C3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_308832</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS68"/>
    <dbReference type="OrthoDB" id="272392at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055207">
        <property type="entry name" value="POLR3C_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013197">
        <property type="entry name" value="RNA_pol_III_RPC82-rel_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008806">
        <property type="entry name" value="RNA_pol_III_Rpc82_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039748">
        <property type="entry name" value="RPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08221">
        <property type="entry name" value="HTH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05645">
        <property type="entry name" value="RNA_pol_Rpc82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22536">
        <property type="entry name" value="WHD_POLR3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase III subunit RPC82-related helix-turn-helix" evidence="11">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III Rpc82 C -terminal" evidence="10">
        <location>
            <begin position="167"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase III subunit RPC3 winged-helix" evidence="12">
        <location>
            <begin position="461"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="633" mass="71103" checksum="8CCA9820B7AA2DA9" modified="2020-06-17" version="1">MAQNFAELCTLLVDDLYGELSSRVFSTLLRHGRLTLAGLAQTSGLTSRQLKHGLVVLIQQHLALYYSSDSDGQTYYEADGINAYMLVRSGKIIRLLQERFGESAGGLGLNLLLLGHVKIKDLADAYGFNKRKGKTNGPEGINGGGIHDEEIDTSHIRSLAELHRVLDELLRAGFVVKVQETHFRPAADIENDAVQAVMESQFPNGVKGTKEKAQLATSVKALKRKWRDGDDYDEYNQSAGTNGVSNGLKRPAPGPAPTGRKRLKLNGAALNGLNGINREDESGSSLDEEMVVRLNYEKCVVAMRSQQLVRLAERHIGYETSRVYEALLRVLERKIRRCHDDLRDYVDEEDDDVAMSPTISSVEVLNALDPDTNLYGDLILDDVSVAGANGGSGIKDDEEEEGVHEVDGDNEEPGRLFLVTRHIRLLCEDPHRFATWVGRRGGGEFRVNFSELTKSLIQHEIEQTVAAKFGRFAVRLIRILYAKGKLDEKQLHLTGMIKQKEVRAVMSTMQEEGFAEIQEVPRDNNKRDTSRAIFLWFFEQDRVRRLLLAEAYKAMSRILQRIRVERDKVQSVIDKAERTDVVGNEDKYLNAAEKLALKEWMAVEERLLVQLDRHDELVATLRDFSPSYSGMVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT89</accession>
    <name>A0A6A6NT89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_97386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT89"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="13479" checksum="E89717CBD00BC766" modified="2020-06-17" version="1">MDQGSMGRVYCLGVCTALLRRFSGLVLSTSVLFFFSLPFLFALVYHWWSIRWACCRCVFRSGSSKVVFSIISHHNNQLIDIILTHLLVIIHRFPCSAFSPSSLSMLLFLFLLSIFPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTE4</accession>
    <name>A0A6A6NTE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCP2 sterol-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_101016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTE4"/>
    <dbReference type="OrthoDB" id="10265837at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1050.10:FF:000001">
        <property type="entry name" value="Putative Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF25">
        <property type="entry name" value="SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="129" mass="13858" checksum="BD76FCEAAF964C6D" modified="2020-06-17" version="1">MSLKNDAFPSSVAFDAIKAALESSPAEKKDAIKKGGAIFAFTLKNKEGKQESWYVDLKKSGAVGSGTAPEGEKPGVTLLMSDEDFGKLIDGKANSQKLFMSGKLKIRGDMMKATKMEPILKKAKTQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTM0</accession>
    <name>A0A6A6NTM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTM0"/>
    <dbReference type="OrthoDB" id="5135333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="198"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="748" mass="84695" checksum="A30FC3CC01695627" modified="2020-06-17" version="1" fragment="single">MSSAMTDMSQGYGKFAEKYCKVCQKAGRFIGCQLALQRTGKARPDDTLLLGNLETLQGRTSCVCCQSILVALTRTGFASYSSLGEAKAQLIFGGSPFHIEVSPKGLPFSGENMLMLRQTEPADVKNRLSFVDYYRALDLTRIDLDLIRGWIQTCDGLHSDTFGQVALDAFDSGLLWLYLVDLEHECLVKVATKEKPRYIALSYVWGRVDMLMTLLENLDRMKQPRSLSFSSNQMGIPKTIRDAMYLAAKVGVRYLWTDSLCIIQDDPSTKTMFINAMASIYAGSYFTVVAAQGEDCKFGLPGLTDCSQPRKFPCHFIEFPGQTMVTGNDLGLAESSVALGTRWTSRGWTYQEAFLSRRLLLFNGTVSWFCHNFRSDEWLAYPHGHENTSLDQTFLPCPSHLIGEIPSWPDISFYVGMVEEYNVRDLTFDDDAVAAFAGVISVLNKVFDRGFHFGLPEMFFDVALLWEAGSSIRERSQLLQRRASLRTNLPSWSWMSTKGRLDLNMWTYFAPEFYKDSTDKELRPLLKWDKVSMLGGRNSTIEYSSPVSSLPPGWSAIHGGGANYRHDSQPGKSFNYPFPISQACRTMDLTEYGTLLHFTAKRASLLKGEPIKVNIRHQGQTQPVIEHFSHTKCSLRTSTGEWAGILSSDCGDFDSPTREARAQCKLVEISECYVSGRKSDPNFHLMFPELEYEDHPLASPTDRVWQNYFFYNVLWIELMEGVAYRRGIGRVIREIWRKLDLETVDLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTU7</accession>
    <name>A0A6A6NTU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_100902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTU7"/>
    <dbReference type="OrthoDB" id="3945698at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="230" mass="22730" checksum="E1327E42813DEBC8" modified="2020-06-17" version="1">MNFIQGAIQNAASGMIQGAVTGIGGFAGDTIIAAGNYIESTGRNIGDVGVAGRFRSYGDYINSYGENAIAATAPNPSSGAVAKKPVKPGNASQKSTSGHAPIGSQKALPAPSKKPEMKALPAPGPAKKKAVKPTADGGAKKGPAGAPKIPSTQQQQQGPGGPAKGPAARKVPISKASSPASQKDTPSSDTAGQAKKKPVTASSKNTSQAKKPAVGSVSAGQKKTPVAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY8</accession>
    <name>A0A6A6NTY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_373535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY8"/>
    <dbReference type="OrthoDB" id="19419at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38502" checksum="855603E611356502" modified="2020-06-17" version="1">MATKEQNNSSAKPKVSEFFQEFLKQNPKEEKPLRQLFDLHSSQLDIAHRHQLEILELEKKYHRQYVDLYAKRTAVVNGAATEDGGKRDSVHSSDAKASSRGLPGFWLRAMRNNPLISRDITKDDEAALAKLKDVRIEYLRRPGFRLQFDFDENDFFTNTTLKKSFTYQRDADDFTGELAYGDAKGDKIRWKRGKNLTEKTAEEDGETVSISVESFFDFFDTPSKEDAEAKRAAKLNGSRPADSETTTNGNQKENDAQNGNDDDDSSSDAGSALEWALEHDFDMGEEFKEKLIPHALYWYTGEAALYESDDESEDGECVVGELREEGEIDDGKEERGGESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU02</accession>
    <name>A0A6A6NU02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPI-anchored wall transfer protein</fullName>
            <ecNumber evidence="9">2.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_352619</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Endoplasmic reticulum membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the PIGW family.</text>
    </comment>
    <dbReference type="EC" id="2.3.-.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU02"/>
    <dbReference type="OrthoDB" id="15270at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032216">
        <property type="term" value="F:glucosaminyl-phosphatidylinositol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009447">
        <property type="entry name" value="PIGW/GWT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06423">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017321">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="529" mass="57871" checksum="C9AC1D9BC84BA933" modified="2020-06-17" version="1">MEDIAGMEGLEGLIAETYKARREAFVSNLTGTTVEEVNLVTLVAAAAICLWSALQARQRFFTPYTILALVTDFLLNCCAILLATTQYSSAPALLNTLLFIPALFLYFSEPTPAVRRANAAKKTKASKLDNANPNSRSVSSKPDPLPLKPFVTTYRGNMMVITCTSILAVDFNVFPRRFAKVETWGTSLMDVGVGSFVFSGGLVSARALLKAGMQTKGPLLSRMITALRHSIPLLVLGLVRLYSVKGLDYAEHVSEYGVHWNFFFTLGLLPPFVALLHSFPFFKAGPKSLAVLAVVVAVAYQTVLDSTELEAFILTAPREDLLSKNREGISSFVGYLAIFLAGQATGMYVLPRERLPPSPPSSSATILDKLRRWCCTTLARLILWAGIWSGLFVITTADSGLAMPISRRIANLPYFLWITAFNCCQITLYAVVEAVWFPGIYDHGNRQQSNRGESERERGQEATSRLLHAFNRNGLAIFLIANLLTGLVNLTLPTLDMGQGQAMAVLVVYTAILAGLALGLDAWDMSIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUF0</accession>
    <name>A0A6A6NUF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_78639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUF0"/>
    <dbReference type="OrthoDB" id="5957327at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01393">
        <property type="entry name" value="RecA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13481">
        <property type="entry name" value="AAA_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="33"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="44011" checksum="502669423D25C0B9" modified="2020-06-17" version="1">MASQEGTQVLSSSSHRLPTISASQALESLKTRERGPISFGLEQLDALLHRGAPGIRYGTWNAKDGLRRGQVVEVYGPPGAGKSTLCMQATASALRGGEHVVWIDAGTPMALIRLRELLKSSLESAGAALNPVDSKGSSCDAMKRLHHLTVPTLAHLLALLIRPPASFPPPETGLIVIDSLSTLFENSYPRNAGSPLAGDAAKWAAGRKYGVMNDLLASLSKIAALSNLAVLISSQTITRIKSGQNALLFPAMSGREWENGVSARLVLFRDWLRPSWRSSQSDSEAGKRWRMARFVGLVKAASTAQTDNPEFTNVIPFTIERTGLCLIDIPATALPTKVLSSPSCPAKRPYAVIADSEGESSTSTDEFDWVEEDAVAAEGLIDVAPDVARGHSDVHGHDTIGADKDEKAAETSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUV7</accession>
    <name>A0A6A6NUV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_72564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUV7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="134" mass="15035" checksum="3085D398F3D9DDAA" modified="2020-06-17" version="1">MEAANSHGWRHGWLRGGALMQGLGFREPIRSNDRNRTSTTTRCQATHYTHPVPWATEPSSLIPECSPLISCDVLFGEKPSKVTQLAFSTLKGAILRTLETLAANSHSKEQWDPRMPKKGIFHSITLFCPYLCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV54</accession>
    <name>A0A6A6NV54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellobiose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_289241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV54"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1210:FF:000004">
        <property type="entry name" value="Cellobiose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="812" mass="86047" checksum="59C6759AB8CACC5D" modified="2020-06-17" version="1">MRSHTDADTGITFWQATIPSTASTGGYEWGMALPEEDSTVNEYIGHLVGAIQSDTTGGWSGVAHGGGMTNHLLLVAWASDDYIMTSFRFATSYLEPAIYTGNATLTPISAKINATHFDLIYRCQWCWTWDHEGNTGTVAPSGDTVVEVMGWAQNLAAPVDPDDADSPLGQQHDNGFGLYGAQVQSARAADYYDWATMGMEETGGATTSTATATNNPSGPPACTPTSSYCSACESAATPLATYDYIVVGAGAGGIPVADRLSENGASVLLIEKGPPSSGRWGGSEFLSMKPSWLEGTNLTRFDVPGLCNEIWVDAAGIACPDTDQMAGCVLGGGTAVNAALWWRAPALDWDDNFPAGWKAGDVTHAEDRVFSRIPWTDRPSADGRLYQQQGFDVVASALAARGWSRVTPNEVPDAKNEVFGHTPYMFSHGERGGPMATYLVTASERDNFDLWMNTAVRRVVRDGSTITGVEIESSADGQCGTIAVTPGAGRVILSAGTFGTAKLLFRSGIGPRDQLEMVASSADGPTMIGNDSWIFLPVGENLHDHTNTDVVIAHPNVTHYDFYEAYDDPIPTDEDSYLGNRTGILTQAAPNIGPMFWQTIECSDGITRQLQWTARAEGSRGTNSTTSMTLSQYLGRGSTSRGRATITELLTMSVSDPPYLKTEGDIEAVTKGLQAVLDALGAFPGISFLAPTANQSVESYLETYPALPAVRRSNHWIGTAKMGEDSGLAAGNGTDAGAGTAVVDTDTRVYGTDNLHVVDASIFPGMMTTNPSALIVTVAEHAADRILALGAYGEASSDDDGTARRSLARRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV99</accession>
    <name>A0A6A6NV99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GPN-loop GTPase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_289859</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV99"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17872">
        <property type="entry name" value="GPN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000552">
        <property type="entry name" value="GPN-loop GTPase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030228">
        <property type="entry name" value="Gpn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF7">
        <property type="entry name" value="GPN-LOOP GTPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="303" mass="33457" checksum="84BB1AE884DCBA5A" modified="2020-06-17" version="1">MSKFGTVVMGPAGAGKTTFCSALIQHLRHNRRSCYYVNLDPAAEDFVFEPDVDIKELISLDDVMDEMGLGPNGGLIYCFEFLLENLDFLTDSLETVTEEYLIVIDMPGQIELYTHVPVLPALVKHLSRGSLNINLCAAYLLEATFIVDRPKFFAGTLSAMSAMLMLELPHVNVLSKMDLVKGTVAKRDLKRFLDADAGLLDEDNTHRSLAFEPAGDGDMVVPVEAGDPSAPRQAGDPFARLNRAVAKLIDDFGMVSFLQLDVQNEDSVGAILSYIDDAIQYHEAQEPREPNDDIDMDPSTYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVC9</accession>
    <name>A0A6A6NVC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVC9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="92" mass="9489" checksum="A8EA0DF6D36B51B6" modified="2020-06-17" version="1">MTPEKWSSMLGLGRFASTTLSTRTRTGVPPGVFPPGCGYVSGSAYYPTGTACPFPTGTGTAAPQPSNGTETRVPDTPIFPNVARAGHLAPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVZ6</accession>
    <name>A0A6A6NVZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_349216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVZ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025694565" evidence="2">
        <location>
            <begin position="17"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="311" mass="30819" checksum="95B0F1A1F6FF4872" modified="2020-06-17" version="1">MRAAAVAALFAGAAVAVPHYSPSVVYVTDVETVTSCPPDVPSCPGTPTPTPASSSTYPETTEGPVTPTPSTTEMTTKVVYSTTLVTITDCGPEVPDCPAHSTMVSTSVVPVYTTVCPVTEVPPEQPTGCSGPDCWPYVPESSSTEEYPVPPTETPGCSGEGCYSSPPAETPGCSGEDCYPSPPAETPESPETPGCSGEGCYPTPPAETPETPTPPAETPESPEAPECGPYGCAPPAGPTGSGSPVPPASEGPCSGAGCPPYPTGPATSTAYPTGTGVPTSPSSPPAFEGAANSINAGMALAGLGAVAALFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW59</accession>
    <name>A0A6A6NW59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ammonium transporter AmtB-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_268897</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW59"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="3"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="266"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="409" mass="44644" checksum="F0A2AD31527D11D7" modified="2020-06-17" version="1" fragment="single">DFAWMLTSSALVLVMVPGLSLFYSGIADNRVMSSMAWYPLMTTAIIGLQWYLWGYTITFSDWPSSHTFWGGSDGVALHNVLLRPVPSRADFQIDGPYIPELLYALFQGMFACFTASLVSGTAARKDRPGHFMIFLVLWATFVYDPIARWTWSPNGWSKTWGVLDFAGGTAVHVTAGATVLAHCTYTRYVLPFVEEVHMKILLGTGLLWIGWLGFNGGSALGANLRAVSACVSTHLAACAGGVTFCLLHAFWFYLFPDEDDSPTNMISEPHTFKWSMEEFCNGVMIGLVCITPAAGYVPLEVAPVFGIGGALMLFFLTGLNFIVNELQDEEGIIVIHGIGGMIGMVFTGLFARGEIPALDGKSDPGESRGGWDGNWRQLGIQIADAFAALGYAFSVTMVILLVLEPFIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH1</accession>
    <name>A0A6A6NWH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_349044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12218" checksum="8E467E9E85D75035" modified="2020-06-17" version="1">MLSRSRSCGALMMRREPFLLSFLLCLSLLSFLGIRLLGGVPEGSSLRVLASDAVGCLRPRGRFLLRRSGSNAPIGHLNRRRPGQKRMRSARSENATRGPLLPRHSDHPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWL3</accession>
    <name>A0A6A6NWL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_364861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="854"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="473"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1254"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1745"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1793"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="122"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="413"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="478"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1745"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1816"/>
            <end position="1837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2112" mass="230788" checksum="4893EBDBB63D1D1C" modified="2020-06-17" version="1">MAAVEAAPAGPGEREKAPAPDGAVETPPNIPDDAEKPVGPDAVSPQEAPGNEDDEASAAPPPSAADRQPSPAPTHEPSTPGEPPPPPPPKDASQNQNGHTPTPPPRIETEGPSQQPPPTATAPPTSAPTSAATSSMAAATAQRPRTDSQSTTTTTATGQPGGGRGGATRSSLVFVQTALETIAGSKDARRNRQLGEALSRALADVRRDGDPHDVDPEVLFEPLRLATEAYTVQVVTTALDCIGKLISYSYFSVPAAGAASSGASGAEGEDGGAASSPRAPGHKEEAPLIERAIDTICDCFQGEATPVEVQLQIIRSLLAAILNNKIVVHGAGLLKAVRQTYNIFLLSKASANQLVAQGALTQMVGTVFERVKARLAAKEARVNNNLAKSSDKSGVGSPDDDMSGAGGARADGSDEGGEGVEGEAEADDSASMAAPSDKPVAKQGGPKITLQTFESRKSFDDARIGDNAPTLVTRVKAGSGGSGSGGSGHKALRRSPSRTASGHAVPDSAVATPQDGSDEEDEVDEIYIKDAYLVFRAMCRLSTKTMAMEQATDVKSQGMRSKLLALHTIHTILRNHIEAFVSPYATIRSSSTDEPTTFVQAVKQYLCLSLSRNGASSLNRVFEVSCDIFYLMVRDLRVMLKKEIEVFLKEIYFAILDKRNAPMFQKQYFLSVLTRLAKDPKALVEIYLNYDCDRTAIDNMFQSIIEHLSKISTVKLDIPVTALQQQAYQEFHSKQVNEQKDRMRQKEILPPSLATAAIHSNLEPDRGFPPEYALKQESLETLVEILRSLVDWSSQGLDDGSRLRQTDSKASVDDLRESIDTREMAGSPFVGVGSAAAAENSGTSTPVAEDDPAQLERVKQRKTAMSDAVKTFNYKWKRGIKVLLKEGFIRSEDPTDVARFFLGNDQINKAALGEFLGEGNPENVAIMHAFVDGMDFTKMRFVDALRRFLQSFRLPGEAQKIDRFMLKFAERYMFNNPNAFANADTAYVLAYSVIMLNTDLHSAKLKGARMTPEDFIKNNRGINDKADLPDDYLKGIYEDIQQNEIVLETEREKAANLGQLPQQPAGGLAATIGLANRDNTREKYVQASEEMANKTEQLYKSLLRMQRRSAKMTVPKFIPASSSKHIGPMFEVTWTALHHALSEAAQSTHNLETIKLSMEGHKLSIHIACVFDLDTPRGAFVTSLTHFTALHNLSEMKAKNVEALKVMLDVALSEGNMLKDSWRDILMSISKLDRFQLISTGVDEGVVPDVGKTAVQPRGGGAHAKRSLQVPQHRPRQHSHSGNTLHYQAEIAEESRSTDIIRSVDRIFTNTANLSGEAIVYFVKALTQVSTMEIENSGQSESPRTYSLQKIVEISGYNMTRVRFEWTNIWAVLGEHFNHVGCHTNTNVVFFALNSLRQLAMRFMEIEELPGFKFQKDFLKPFEHIISNTSVVTVKDMVLRCLIQMIQARGENIRSGWRTMFGVFAVAAREPYEGIVNLAFDNVTHVYNTRFGVVVSQGAFADLVVCLTEFSKNIKFQKKSLQAIELLKSTVPKMLRTPECPLSLRYNAKGEKDAPQSEGVPKQPSTQTEEEQFWFPVLFAFHDVLMTGDDLEVRSRALNYLFEILVKYGGDFPQDFWDTLWRQLLFPIFMVLKSKSEMSKVLNHEELSVWLSTTMIQALRNMISMFTHFFDSLEYMLDRFLDLLALCICQENDTLARIGSNCLQQLILQNVTKFTPEHWNKIVGAFVELFARTEATALFSAATSGSYRSSSAGSTGPNGFREPKTPKTPSLDTGSIADMPMTETPVEETNALGINGLGVRPGSSASISSDGTMRAGTTESSSPSGTKSPPSASATPMSERELEDYRPAHAADQPQQTPVVVTAARRRFFNQIITKCVLQLLMIETVHELFTNDAVYAQIPSGELLRLMALLKKSHHFAKRFNADRELRARLFREGFMKQPPNLLKQESGAAAVYVSILFRMFGDSAAERAASRAQTEAALVPLAADIIADYAALDPDTQARNILTWRPVVVDVLDGYAAFPAQPFRTHVPRFAPLLVALLNRDLGPDLSLQRALQGVLARVVEEGLGVPLGEHAVVRTPGGGAGSPAVERRGSWIGGGSVGMMARRGSRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX97</accession>
    <name>A0A6A6NX97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX97"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025631607" description="Secreted protein" evidence="1">
        <location>
            <begin position="34"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9776" checksum="A294D4C9A0055E0B" modified="2020-06-17" version="1">MGWPWAAVRRPRGSIVTSLLLLLLLLPLAIVRASCFGGFRAAVTEGLGARAREHVRGPTRRTPRVFPRARSLPSSICCPFYRIRSFNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF2</accession>
    <name>A0A6A6NXF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_349170</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXF2"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000006">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000004">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000052">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="17">
        <location>
            <begin position="297"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2455943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="598" mass="67439" checksum="D6C5734D2DF674F6" modified="2020-06-17" version="1">MPTISVDKAELFNALGREFTTEEFDELCFEFGIELDEDTTDSKHPIVDGVEEPPQLKIEIPANRYDMLCFEGIAMNLNVFLSRNTLPNFRVVAPANGELESITVKPETTQIRPLISGAILRNIKLNKTRYDSLIALQDKLHQNLARQRTLVAIGTHDLDTLKGPFTYEALPPEQIEFVPLNQEKKMNAKEMMEFYEKDRNLGRYLHIIRDSPVYPVIYDSNRVVCSMPPIINGNHSKITVDTKNIFIEITATDATKVEIVNHILVAMFSQYCDEPFTVEPVKIVSPHNHQSREVPDMTPREMQAEISYLNDVCGLKLSPEDICKLLTRMCYYAAPSKADANTLDIAVPVTRADVLHQADVMEDVAIAYGFNRLPRYYPSKTAAVAAPLPINKLADIVRAEGAMAGWSEVMPLILCSHDENFAWLNRADDGATAVKLANPKTAEYQVVRTSLLPGLLKTIRENKSHSVPIKVFEVSDVVFKDLRLERKARNERHFAAAWYAKTSGFEVVHGLLDRVMLMLKSAFITREDGIENEKIEGYWIEELNDPTYFGGHAASINLKLGGKHHVIGSFGILHPTVLKRYELPYPVSALEINLEVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY49</accession>
    <name>A0A6A6NY49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_39840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY49"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="18256" checksum="1D9467F490931ABB" modified="2020-06-17" version="1">MPVSNMSVANRIYHWIPEPRSRKRVLDDDPEPDVRPAKKSRPSHVGVHRPNSDTKKNARKRSHPDTPKSRLPSEKPKVNCPPAKHPKRPQPQIEPRSPGPNGSNLDVARKSDRIGTRPEFLRGNARQSSIAKKRTSKPQAEPLRRSLCVARQRTRVGQSGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYZ5</accession>
    <name>A0A6A6NYZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_322395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYZ5"/>
    <dbReference type="OrthoDB" id="5376138at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000088">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="84"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="559" mass="62694" checksum="420CE9E92D623A20" modified="2020-06-17" version="1">MDDSPRHALPGQFQNTSEDPAPDLTKKILAWDEFQRLPSNPCTPPDLRQWNPARPCTSTQKLLQESDCRSVLAVSWHSRKKWAVLWAVFGVQISMNFNAAVYPNAERGIAADFGLSHGRVALGMMIFLVTYAFGCELWAPWSEEWGRKWVMQASLLLVNITCVGCAIAPNFETVFAMRFLGGLFSAGGSVTLGMVADMWEPEEQQLAVAFCGLSSVLGSVVAPIFGGFIEEYLPWRWTFWICLILGFVVELTHLMVPETRSSILCKREARKRRAMGIDDCYGPGETAESKISLKEICRIWARPFIMLTTEPIVTFLSLLSGFSDALIFTFLESFKPVYDQWGFTTVQRGLAFLPLPIGYFLAYAMYIPMVKRQRALVRQHGKHALKPEKRLKLLLFLAPLLSIGLIGFAWTSVGPPVHWIGTQFFVIPVGMANYAIYMGTIDYMVAAYGPYASSATGGNGFARDLLAGISALYAKPLYQNIGKKYHLNWASTVLSVLGVFVTIPLFIFYFFGPAIRKRSKFAKQIAQHREEDEQRQGPSNTQQGGLWAQQQVEVRNLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZF0</accession>
    <name>A0A6A6NZF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_421673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZF0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025482187" evidence="2">
        <location>
            <begin position="22"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="22315" checksum="D8FD017C9328EC97" modified="2020-06-17" version="1">MRVSNFLCLFVSLSLASPLLGGVELSPEPRMTCLNTSSPGTKRIIYFTAHIPLDRQRIEIEHFNGSMQTFAITTPWLVAHKTHLRDTLDELGFNVNTHWSLNKRCGWRSLGNVTGAGVPRGELWWLPLYANNFVANRTHEERLRPEFEYAAKMAMLKSYPTEEIALIVVGIALPLLASVLCWMLCARSRGKKAKKSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZS9</accession>
    <name>A0A6A6NZS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin interaction domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_371879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZS9"/>
    <dbReference type="OrthoDB" id="4489171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055335">
        <property type="entry name" value="Ucp6/RUP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39597:SF1">
        <property type="entry name" value="UBA DOMAIN-CONTAINING PROTEIN RUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="811"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="544"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="638"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="914"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="937" mass="103570" checksum="49283BCDDEE431D5" modified="2020-06-17" version="1">MAPMVSDDDIDTFVDITNAGRDVAINFLKHFNNDMQMAVSTYFDNPDKVFTDDSYDATAFAQDRYVEPPEIEFMRSFQIDHAPDKLNAFNPSAAPTRPPSRASQRAPDYNVDAIRGLFPKRRKISNDAYMSYLPTPLGNDSSTITGGNQEMGVVGGDGTVAPGIYFGPATKSSYDNSWALVPTSGGAASTTLEVIPDPDPPQRRRGGTGSGRAPAFLKPLPEGDRLPAMVSTIATIPLVRRALFNHAPVLEDYGYDPNWWSGAQVTAPEVIDLAADEADVFSISPNVGAHAILHETQRLVAFLQGTNRAYGSAEPLSRLPRMASIVETNKSKGFTASVSILQGLHEAVTGQNFDGLRNIREDRGANDPMQGELPPEFTPPESGSPGSTTATVGRDSPVQDESTMEPASPSKTKAEDKQGDELMPDVDAAPNSAATPSEALWKKLFHSEVIMREDTAIDLYDFWNLELTSEDPDRERSLYDVIDWALWAHDWDGNRADVEYYISRLADVFSIRVKQADASKRGLNFDVPARLWVDRWLKENVETTRTMRKEMAGYRAEIKELEARSEKLRRFRYEKKGYSGGAGEVKILDSKELLRSSITLLRAEQTRLRLVGFSVGKEKGSDGNVEERLVQGQSEEEARKTQRMVEGMEEKLEELNRKIEAVDVDIQRAQACLERFSKVWKEPVSSPDQAPRHKLNLCGFSTDARTMYIFDPRTPKLAESDAESVDPLSTPADKQWWKIQYLNDPRIVRERLTEEAALEAARTESRDVQLVYATDDALITDEEESLPPALAAFVSRDNDAFGTEMAIHAAELASPTDQSGNWGNPPTYKRDAEEKTGEKSTNQPMEEKPGAGYALLGSMEASDYAKAVSNGKADTVKSDGPDEEEEMMSMAPRKAFADGGNGRNSTGDVTMGGTEDKRSDPHDTSIEPKETKFFEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZT7</accession>
    <name>A0A6A6NZT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-actinin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_345175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-actinin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZT7"/>
    <dbReference type="OrthoDB" id="10017054at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21215">
        <property type="entry name" value="CH_SpAIN1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21291">
        <property type="entry name" value="CH_SpAIN1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000138">
        <property type="entry name" value="Alpha-actinin, sarcomeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000097">
        <property type="entry name" value="Alpha-actinin, sarcomeric (F-actin cross linking protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000279">
        <property type="entry name" value="Calponin domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000223">
        <property type="entry name" value="Related to alpha-actinin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000030">
        <property type="entry name" value="Related to alpha-actinin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000077">
        <property type="entry name" value="Related to alpha-actinin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014837">
        <property type="entry name" value="EF-hand_Ca_insen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08726">
        <property type="entry name" value="EFhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00019">
        <property type="entry name" value="ACTININ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="10"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="124"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="484"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="636" mass="73454" checksum="C4E3C5E6850823A8" modified="2020-06-17" version="1">MAPLEEKWVTVQQKTFTKWLNSKLKVRNVELVDLVKDLSDGVVLIHLLEILGNESLGRYASKPKLRVQKFENVNKALDFIKRRGIQMTNIGAEDVVDGNRKIILGLIWTLILRFTISDINEEGLSAKEGLLLWCQRKTACYEEVDVRDFSASWSDGLAFCALLDIHRPDLIDYDSLDKSDHRGNMQLAFDIASQEIGIPDLLDVEDVCDVAKPDERSLMTYIAYWFHAFSQMERVENAGRRVEKFLTNMQGAWEMQSSFERRMRELMRQIEEQRKNWEDAEFEGTYSDAKNQAAEFTNYKRDKKRKWVAEKSDLVGLLGNIKTKLSTYRLRPYQPPPELSLERLDQVWAGLTRAEHDRSQVINETIRDIKNALRKSFADKANDFALALNTLSTSISGLEGDVEDQLRHTREISKNLQPLDEFLGIISKIDQQCTEANIEENDFTTYTYDELEYELGLVKSSVSKKLAFLDNQMVARDMTNLTPIQLEEFESVFRHFDRDVSNSLQELEFSAALASLGLVYDEDEMHERFMETSGGRDQVTFEQFIRFMVDVTEDQNTAEQVFESFREVADGKPYVTELDLRHSLIPEELIDDLVKSMPTHRGPDLQEDRNLPKYDYISFMEKYMGGERSNGSTNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0J7</accession>
    <name>A0A6A6P0J7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_303621</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0J7"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="201"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="477"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="519"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="557"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="593" mass="66132" checksum="27B49D25DF5746BF" modified="2020-06-17" version="1">MAGNVNARTLFHLVPVNQATHNALLHPDNNHFVSTSAKGPGLEIGFHVPSMSRGRVMTRLGRDADLILPGRDVSAVHVAFEIHPETHVVLLSVRSKRSSTVTVSNEGTPGAQQISEDCVLVYGICYKIRVTSYMFNLLWRDAKTVESLRELAVEGYRDSLLRLQNVRSRDRPTEFTDSELHSWHNTRLHTARKVLFREAEGAPRVLIGAGAFGAVYRAVDFESGNPFAVKVVRLDTLPDTKVEHARAALHREIKALEQLKHENIVECLGVAKFDTNNPEIFMPLRRGNLSLLIKNRERQCSEDKLCSQVLEQMLCALDYLADRGLCHRDVKPENILYWQNTAPEIYSFQLADFGLVNHQQNATTFCGTGFYQAPELYDVDRFPQSPKMDVWSLFATIIDVHSKFTFPPRDARNYYDVLQAARAAVLLAPELADMAREDPAHRASAAQLLVAHFNGRGLTTRRAAVLPIWAPPSAECEQTVLGGGDPSSSGAAPTPVPAPQAPWAAKASPLIVYDARHRRRRSKELASPANTPPPTWARRDGGIVKTRAPSSKPAIRHRVEEQLDKELSRGQANKELEKGQPEREFRIPGSFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0M8</accession>
    <name>A0A6A6P0M8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0M8"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="177" mass="20620" checksum="64DA627B78016FB2" modified="2020-06-17" version="1">MARHNTERIPASHAVGNSKAYAIKKYLHMLKIQSRIITDTERTHEYMYFLLGSHSTPYYRFNVQKGLEKMRLDDYGEKKRKLPRQDLDRGDAFAPQPMESVTFGQNPNDSPPERQKSFRLTKRSSSFEILGTMQYLERVTEAYLRGQETIIRDMSPGVNVNDNVHACAKRHWRTLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0R4</accession>
    <name>A0A6A6P0R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_385836</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dual chitinase/transglycosylase that plays a role in cell wall architecture. Chitinase and transglycosylase activities are coupled. Required for the polysaccharide cross-linking at the septa and the cell wall. More specifically, transfers chitin to 1,6-beta-glucan in the cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0R4"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000152">
        <property type="entry name" value="Cell wall glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0430">Lectin</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025483843" description="chitinase" evidence="15">
        <location>
            <begin position="24"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="16">
        <location>
            <begin position="12"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="267"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2457595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="49921" checksum="203DA18366E68228" modified="2020-06-17" version="1">MRSINAFLSALLSLAFTTTPTAAQTWSSCNPLTQGGCPPDAALGKTVHIDFTDGASDSFAGQGNPTYDSNGASFTVAQSGDSPQLTSIWYIMFGRVEISLKAAPGAGIVSSVVLQSDCLDEIDWEWLGADPDEVQTNYFGKGQTGTYNRGAFHSDPGSQDGFKTYTIDWTPEQIVWQIDGVTVRALRPDDAAGQYPQTPMQIKMGAWSGGDSSNSPGTIEWARGPTDYSQGPFTMQVQSIMVADYSTGTQYVYSGTSGNWQDIEAVDGSVNSGGSTESVDTDAPAVTESSSGQPIPFQGTHQDDSSTYVTPSEYPWVPRPTTMETSTVTATSYPGLPSGWTVSDSGKVIPPSAAPSLTASPVSSPALSQPAPSSAAAPDQPAGGYEVITTYDQQGFTTLLTVPAGHETMPRVYDSQGFLVTDAPAAPQSTGTADAAAAENIELQNQQEGDQNDASSGLVGLGAEFKVACAAALVAALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0R5</accession>
    <name>A0A6A6P0R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_285746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0R5"/>
    <dbReference type="OrthoDB" id="10265193at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06903">
        <property type="entry name" value="lectin_EMP46_EMP47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035661">
        <property type="entry name" value="EMP46/EMP47_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0430">Lectin</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025357722" evidence="8">
        <location>
            <begin position="21"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="21"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="464" mass="51880" checksum="DD8DB6A7FA4CAF26" modified="2020-06-17" version="1">MRFLHTLQAFACLSLVLVSAQDVLNGLSFGHQQRLTDDGRTISGWTVAGDDYTPDLLSDRVILTPPYPGNKRGAIWANAPVDLAEWTAEFYFRCTGPERGSGNMQVWLSKEHIGASSVYTIGQFDGLVLVLDQWGGRGGTIRGFLNDGTVSFKDHHNVDSLAFGNCDYSYRNLGRMTKLALKQAGGEFVVEVDNQLCFKSDKVQLPQGYFFGISAASAENPDSFEANKFIVRSGTAFGQQQNQYQQQLYENERQAQGMPIQAEQQRPPQQQQQQQQQQQQEQQQDNTPPPPEVPDIPASSVRSPEEQFADLHNRLQMVNYQVNNVYREGTNQRRVNNDRFTALMNKLDALDAKLDSLGKSIVGLSDQIVNVEKKAHKIEQVSMDMQRSGDDRKVDKQFERMHAALKDSHANMMTTLPSAIARVVSASAPKLGMLLLAIIVVQAAMAGVYMLYKKRRDAAPKKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0U9</accession>
    <name>A0A6A6P0U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_29977</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0U9"/>
    <dbReference type="OrthoDB" id="3638488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF400">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="381"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="766"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="930"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="944"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1059" mass="119302" checksum="BDD7C5FEFF43069B" modified="2020-06-17" version="1">MIQFINSKKRKAAGSHSDASTNQQGLLSRTSSSSTSLAPAGPTPCESTKSSKLKRTSRLLFFLGLGKLARRSSEASGNIRDLHDGPSCAALSVYDRNAASSHLATEGSTSTDTCRHSLPTCHPNAGIEVDGPSDRPTSYTGSSQSVAKHVTTSSSYSRRNSRRLPFVFNQQTVVRRRSPHKRLNVPRSPDPMPHHTPEQFAEEGGEPQGNQLPLSSSPLSSPVTSHTTLSPTTTGKTSFFSDAIIGRSGEAKFFRDLGIARINTNSTGQDDGRRTSRDSCQMEPVYESIEPSIRTVEIVASAKSFFETYFNRIVSTPMSPRSERRRDLKDFFAKCKTPEEEQSAIMNRWVEAESENLRQCRALRSKAFVRRTYSSRCIGGYETVRVLGKGSFGVVRLVQTIPETSQQLPVQNPHRHESIRSVGSEAKSKVECKDFGRPEPQLFAMKVIRKSEMLRLSQEAHLRLERDYLVAAEKSRWVVPLISSFQDSHNLYLVMEYMVGGDFLAYLMREDVLHEHVARFYIAEMILCIEEVHRMNLIHRDVKPDNFLISSSGHLKISDFGLAFDGHWSHNQKYYNERRWSLIEKFGIKIRGDVSDRDQDEREEASKKIGNVLNRCFAGRGKKTPEPQAEPEDTAENVLKTLNHRHMKEFARSIVGTSQYMAPEVVEGENYDGRCDWWSIGVILYECLFGYTPFFAETRSRTKWNIKFHQQCLCFPDRPRVNRPKEEAIALAPVSACAVHLISSLLVVRDRRLSCQRYRDNDAVLTKEPKGTLRRRRTSEPGENSLHSNNPPPQSIRTGQGGVVPVAHHPDHPRCTSQEQQLRRPHFVFTDDAEDIKSHPWFTGTHWDRLHEMRPPFVPRVRSGQSVAKYFEPESEICTHSEDLDGAVSLSDSEVEEAVKEVEGVANVDEAGKPNIRHEHWGHEHESQMLEGTRAGSGTQQEITGEKRAKGAPKKNDDGVAAIEGGETGDQKSKKILRKIERKRPRDKILRDIDCGPTALDIRKKLAFLGYTYRRQELLLLNELVESTSDAAGIRRKLVPNPRTTKRKSALDVVAPVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P199</accession>
    <name>A0A6A6P199_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_29233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P199"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="231" mass="24948" checksum="0F5693F1B5A73F5B" modified="2020-06-17" version="1">MVSRPPLRRRPESGAPSCQQKGREPARETTGLPDPPRSLPREPCSQPGPAPDEHFAPLQPRVSHIRDNALSDSAPSGPVRPLQPPAPPPLSALAPARSCTSYPPAPLDLLDTRRRRLHVLKSPAATEAPATRSGNPSFAAVRQLTGPLFGEPGILCLATWLLGHLALRRTSGEQTASGSPLACRSPPIRFEQRRKDESTSTPCFGLASHAWICLEENFVASPLRFPDLFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1L0</accession>
    <name>A0A6A6P1L0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor of RES complex-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC26 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1L0"/>
    <dbReference type="OrthoDB" id="6022at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070274">
        <property type="term" value="C:RES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018609">
        <property type="entry name" value="Bud13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051112">
        <property type="entry name" value="CWC26_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809:SF0">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09736">
        <property type="entry name" value="Bud13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="334" mass="36711" checksum="6AEAC4C2C0360E1F" modified="2020-06-17" version="1">MSLADYLAKNYLNADGPGPSEKKSKKRKRKAAAAEEGGLIIADDDAPGWNTGSGTKDDDDDPSSAIISGHTAEFRKAKTNNWKTVGSTAPSNTEQAAADAVLASAAAENAARAAAEDDGPEVVGGIQEDDDDDDAQVMDSGAKAGLQSAADVAAQVRRKREAERRAFEAQGGAATGKGQETIYRDASGRVVNVAMKRAEQRRKAEEEEQKKREQEEQAKGDVQRLEKEKRRQDLKEARTLTVARYADDVELNRELKERERWNDPAAGFLAKKERKSATGRPLYAGPAAPNRYGIRPGHRWDGVDRSNGFEREYFKAQNERRAVQDLKYAWEMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Q0</accession>
    <name>A0A6A6P1Q0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_385591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Q0"/>
    <dbReference type="OrthoDB" id="3595585at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="631" mass="69351" checksum="18BD2A60FF1DAA12" modified="2020-06-17" version="1">MPAALTVGVNTGLASANKPRSAGRDKKEAKAPVVTAASPTSARDATAANSGIGSRPVRLHISPLTPELLPVYLGPALLAQASDVSFHALRAFPDRAYGYVTLPGMEAERARRKLNGSIVRGGKVRVEEARPETYEVKREERKRKSEGEAAEEEAKKKKKKVREEKKKEKMRKAEGILPGVEMPDGRKVKRGWTEPEKKERRKDRKETKREEKDKRDRKKKQQPSLYSEKPEILFKTVVPPNKSDAIETRSKRKDKDKKDKKKKSKKGEEVIVHEFKKHKKHASFLKSSEVDDSNKPVSEYVEGKGWVDADGNVIEEEKKSNRPKRKSKSKTEDVEAAVDGAATMVKSPTSETASSSELSSSEDEDGDEDGDEDKDADEEDEQQQAGKGADCNKVAHSSPTPAQPAVVPATSSPLPSQPTVEVSAPSPTSPAPGSAATPQVHPLEALFKKPAAGNDNDGKTGRPALPAPILTSFSFFGSDDASVAGTDGTSGPPQTPYSRQDMMTRGLRSAAPTPDTAAISRRFSLPWARGSSDPIDEEDEDEAEALEGGEEANELDMDMVEGEVDDEVEEDAERAGSGPDGEKEGEKPKSDFEKWFWENRGRLNRAWKQRRREAMKASRQQENKRMRKRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Q3</accession>
    <name>A0A6A6P1Q3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_16034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Q3"/>
    <dbReference type="OrthoDB" id="26149at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040144">
        <property type="entry name" value="RAP1GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10957">
        <property type="entry name" value="RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="756" mass="83513" checksum="7D386A445A3E5144" modified="2020-06-17" version="1">MLCLPTRITRIHFFKLGSPSKYETMDWSAGFFQVEFWKIDGQEQSLVAFDRYLKNEDLSQIFQFWPWLTRLGLLENTPASCVALQILADHSKIERVKEAYADSGILNECLNALNPQSGHQHVNEQFLRVIGNCCANNDDNRRVTIAYMRQLSACVSRQDIYETAIKALFNICNENSDTQKAALASGLDIQLAQSLCENWVDLESPETEYVVDLLFWMNEHMSDEYTLRAGAKHVQNIESAAERIDSFECYVNLVWVVLTYLKSAPFRSMIAGDWVNHKSVFGLVKSIASQREKIKANWMQQRSTIPTASDDLSEDLADMHSQLDGIQRELLYALAELSSEPSFSNHGAVSETVIRLNHWLHHGSSELERTVACIMLGNLANNDGTCRRMVLKADCHIAVLRILHRADGSKERLETTFAAAQFLKNLAKPPQTKPHIGLTGVKAALRIMQAYPGEPRLVLQAAGLVRALVQGQRDTAAYVVTGQRLLPDSSELSSPAMIASSEQDASSTVVGPDASQSASKRLTPPMSATENQDSAKLPSPLTILSSFLNSGPAFEKHVSTEIACAVVALVRTLSNARDAETAAETANPLPATPGDVQSHSEPPRDWGGQGKGKGKMLATSAVDTVLDRLVRMDRVPEAILRLLIDESDLARWEALVGLGHLVRVDKGARTVRDALKNSRESGKIFEVLKDMISASQSGPFSSKVELENVERAFEGVTDENEVKHKATPPPMLIPTPSCALYPLLLLLPLIPTFPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1U2</accession>
    <name>A0A6A6P1U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_15938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1340"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="653"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="880"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1482" mass="158641" checksum="9975CB55F142F54C" modified="2020-06-17" version="1">MGQVHQGQAPSHDDRQQQHGSLSNHQGSGGGCVGQLPPASQPSYMEFSSSDSDLPPTRVRSNKFKETVRRARTSLGSLRRTKLGRGHSCDGANLHSAVVAEDQDIDEDAHREKDKSLHNPLQSEPQDDSADQSPPTGSQPQSPSEPPRRSSDFRPATIHACQSTPRAVALQADQAATSLSSPGGGAGSPAGPAAAPTRPLRTEETTSTTRSSLSRRLHSVTSRIPRPHVRGSLFHFLLAGPGDEVAGNTAGPGRPGDVAPFAPAGTAATSGDAGAGRTAENGARDASTHRGRRQASDDRGATPAPTCAAAPSSTAAGSEATRAADPKVREGGEGSGDLDAGHGGGDKTGDETKSVGSTGRGGATTQETGSERAISTGATAIATAGAIGGTSTNDDTGASPLYAWREELSKACTRRQLLAPRQLAEARVERARIFLDLQLKKRSMSPNEARMERARAKLSEQLKGQSSSLENTTLVESLASSLSSAAVSQDEPQSAQGPHLPSQSAPPPKVAVNIPKGRFSNETQSNMSSETGGNDMKKDSVELSKAVSTPILPASGGFTDVPADSVCINGTSSASSSPDSSAATDWFDHIFDEVRPTSTASGRTKGALVPFAPDYMPPDFGLSVAQPVAHISPKVPNGFALSPTTRPAPPSRPVSKPVKPVSLASLPTPPSLTQPPPDPPATSGPRIRSGLPPPYAPSPLSRPPMQTTGGTPAPQEPPPPPPPTPSNKPPSQPGPPNPGPQTPSQHDELAGDRVSEGGPAGPLPSAVQKVRSNKLARNGSSTGRSRLFTCVPLPHVATMALHLRSDFEAMRREIAHGLAVDGVSRARNSENGRNGSSEFGDDDDERSKGRRPPWTLTVSRVRRGGRSGEGARSGNGGKNGNERMNEHARMNGNEGKNGNGGMKRYGSLNGNGYKNANGGGNWGARADGFVAHETSARAVVVEPLRGESGPWNAPSRLWNEEGVGGDKKDARPRFGVRAWFDEDFPQSSFIAQEKQNTPNVVDKPNDAGTGFPGSCSNSPLISRNHSPVLGINNASDNTEDNTNTYTTHSNSQAISSNSSNANSDFIDTSNNPFGKDSHQTRWAASAKAYAQSGHQAVILDKKADFTQSGEEQLILLGNSEKQVGMSDTFVAHTTMTDPKYSVEVLTSDKGIVFYLPGMCTIKLANDSCTEREIFLHLLNNHLRPERTDVVSIVRWARDQIWWDSDVERALRQNGFFWNVGITTAEKMFVLQLAAERTYEKKNRNRKEWEQGREAETQDKKNDEECQKRAESSSAAGLFPCCIPTGTSTTPPSPTSTTPCYAPKFVSEDVSRAALKLEEIALGPEGSRAFRSLLQHAAKCRKSPRQIPGRDPAEYDWEDAPSRLDKPRPFTGKPWWELVPEKLILQGQIQPQAIRDWFALVRLRDAWGISVEADDLQDVLTPYCARADEAARWPDHMGDFLGSVWHRIWHYRVLYKNALLKEHEDIADFSRRHNYRKWKHLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P218</accession>
    <name>A0A6A6P218_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mechanosensitive ion channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_363631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P218"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF14">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="41"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="723"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="771"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="812"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="823"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="849"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="886"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="917"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="946" mass="102265" checksum="EA9BD17166DE6876" modified="2020-06-17" version="1">MSGTHNGFSRQGFEPIPSPGTMSPTSKDATINIPLERVVSHGSAGGAGRVSSTAPITEQPRGGEEDMRSSEKSGGLFHRTRGRRRVRHANGSGQPGDALNLDGEERSLNRMGRIYNAILNFSIVTRYFIYVLPLALCIAVPIIIGATVAQDARIGTVQIVWFFVWIEVVWLSLWVSKIVAHFLPMIFQFLMGVVSPGTRKYALVLTALEIPLSLVGWAVTSLATFVPLMTRNPDARRRAEDDPAADDTLPWMVIVQKVLAASVVASLVFLGERFIIQLLSINYHRKQFNLKIKDSKRNVHLLGLLYDASRSLFPAYCNEFAEEDYIISDAINLKLGSKPGTSNGNSGSATPMRLLQDVGRFGDKITSAFGNVAHEITGKQVFNPNSAHSIVVEALEKNRSAEALAKRLWMSFVVEGREALYQEDIVEVLGENRREDAMECFGALDRDGNGDISLDEMILTVTEIGRERKSIATSMHDVDQAIGVLDNLLCAIAFVIVVFVFVAFLNSNFTTTLATAGTALLSMSFIFAATAQEVLGSCIFLFVKHPYDIGDRVDISGEFLTVEHISLLFTEFKRVANNKSVQIPNIVLNGLWIENVSRSKAMREQLTIPVNFDTSFDDVKTLKAEMQAFVLDKENSRDFLPEIEVEVLGLGDLNKLELAVEIRHKSNWANEAVRANRRSKFMCALVLALRKVPIYAPGGGSAGLGDPANPSYSVAISHEEAERNKASFADDKDAKRLFPQNKPASPAGECEGSAESRAIESLTQRPPAMDPARDDWGPRDDDTTAHRASLSSPGLPPGHGGADSGAATTTASERRSVDEMRGMLRRQSTRGKRRPGSDIEGASSASGPHGPGVGGGDGAGAGAQSLGGAYPGVPTIVEPAPPPSYSARAQQGGQQGSRSPPRGNAFAEQALRYQAPAPTPPPRGAPPQGPPPPTPPERRRPPYGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P307</accession>
    <name>A0A6A6P307_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_284690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P307"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF36">
        <property type="entry name" value="PHO85 CYCLIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="60835" checksum="22CFBBF7C4F35B93" modified="2020-06-17" version="1">MNFDFPQQQTWGATSSRSHPYEPSLSSSASSSSSSVFSVEASSQSSNSSTSTSNSLHIWDDDSWNSLRPAQAAAQQERSGASHVPNHDFTMEQPADTQSLRALQCGRRMFLAALILASKYLQDRNYSARAWSKISGLKVCEINMNEMAFLEAVNWKLHIPDPLFERWQDVVLAYTPSSHPPPSPGTGCSVVNKWKEVMCLLTPELDKVSIRPRTPARSRRPDVFGIRSPPPTIPEVPSEESTPVPMVRLPQYLEPKPDMLPPTPSLIRMGPLPTPQMTPQSTASSTPGYGQCTLPGLRPAMCSAMAQAQSACMSRTILDTWNPAAVLRSNGFDGYQFSGRRPSLAASTVSSASSPESMVSDNSSRSSRSSSICSVSSSAAWAPSSQANLARMATCRNARLPYPMPTQKESTCEYIASEPVSSPDFENFNISDPNAVSMSGADESAKSRKRGRASADLSLQQNVRAMLSASSSTTSSTTSSTVTPSSFSSPTPDAVLQDCSVASSFLLQSPSCVTPSAREPQSPCSGLERRRPVPKDLGRKRACCANEANLGVPREGPGMWRDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P318</accession>
    <name>A0A6A6P318_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Alpha-NAC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nascent polypeptide-associated complex subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_414711</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATPase d subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAC-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P318"/>
    <dbReference type="OrthoDB" id="35799at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-0138">CF(0)</keyword>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="20">
        <location>
            <begin position="57"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="136"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2458366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="385" mass="41617" checksum="6A10C857D93A9D9E" modified="2020-06-17" version="1">MSSSRIEELPDEPESTTKGAKTAEVEDAASSSSESEGEGAEGGDASIPAGAQVAVHSRNEKKARKAIAKLGLKHVEGITRVTLRRPKNILFVINQPDVYKSPSSNTWIIFGEAKIEDLNSQAQANAAQQLANAEAAAANAGGDAHAGHDHGEKGKGPAPESADAAKKAAAEEEEDDGEEVDDSGLESKDIELVMQQASVSRKKAVKALKENDNDIRSAALKIDWAKVPQQLGLKGSTATSLQAFKKRHDDALRKLNMLKEQSQTVDFARYRSTLKNTAVVDEIERHFKAFKPTTYDVNRQIKAIEAFEAQAVKSAEETKSVVDSELKDLEKTLKNIEEARPFEDLTVDEVATAQPQIDEKTASLVSKGKWGVPGYNEKFGNLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P351</accession>
    <name>A0A6A6P351_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_319422</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P351"/>
    <dbReference type="OrthoDB" id="5422384at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="600"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="959"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="171"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="617"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="964"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1192" mass="127468" checksum="A9F2FB6D5F63CCA5" modified="2020-06-17" version="1">MFRPPDSSSPPSTPDSRQVSRGNLSNPSTTPAGPPPDTINTSASFTPAGPPPSSVFGSSQLPQSGATGFPSSINAGRANGSSKGNNLFGIPVSAGGSSKPKLFDPPSTSASQKGRFDAPFSFGKIDAGANSQTPGFASSAFTPFPAGEKSPRHTQRIGGSFRAPSSSPPGSDDDGQGNDDDGEYEEDDAMGDEDEDMDAEGDEDDDLDLEDPPRTGAFEEAAGFDNSFLSAYEAPSPKKRAPAKVLDVTKLAKDLYTGKRPLSNEPDGFILKLEQLMGPFPTRLAEYPAAAQNTIHRTVQDLKSILRTYGRATGNFDDADASYYDGIGPSHADSTGLSKASFLGNLLLQLHHPAPYDANPSLSSSTYGVLSPPSPNLVPIPRAIAYYLTTFHDPLKPDYEALLRRYSNSGGLSAAPEFWDILFQRLIRGQFPAVLSLLKNGRFEVAQTAMDDGKSSPGYTGPQLSHVNYAVDRAISLLESCPAVAEDDWDVAGDPWRLFRRRVRQALHELRTFAEGVPDEYDHDEFEASNFGLSSKRSGAQTSFLGTEARKAGSRIPWTIYQNLRSMYNQLLGEHEEIEQTACDWLEASLALALWWDGEEEEEDEESQSGNPNYRRSMVHHSHRPRARPVDVTPLDAYQRKLARSFNEVMANGLDSDVDASAVGDMVLNTSKALDVGAACALVGDVESTIHVLRMWSPAVAAAIVEVAEAADWIGAQGASGTAGGGNGNGVMGAFDKSDLMVLSFGRNQASKNGGAAANGAGGMKDNILCEYAELVAKRKQLRSEDGKIFRAGWEVAMQVLGRIGDEKVAKEKIASLLDGLPLDTVQDVEKILSACARMGLGELGESMAERYATKLLDVPSSTPAPYGDALFFFARAHRRDKVRDVIDFLTAVSLVHSTPFPAQPNLDANLARLCASPREGLTDLAEQDMSAAQLLATYISGYATLRRFYALRDEGIKPGGDSGGKHGSEAGSKRKREARDEQPKRGLKRRRREAGAALVGVVESASDCIKGGLYDPSVDVVVQVDNVLVLLGEALPLLNQENSAFTSKQLTTLLRAMEDFSTAPSSIRAANVDCLRTALKNAHASSEARGSAPNGAAFPAALQKSTSGLSASTQFSLVGSSMLGSVTSGGTGTSGSSVLVDSFKDTESRKRGWDWRKGFGKDAGKDEVVRMLRLSLAREMAKAWVETEGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P368</accession>
    <name>A0A6A6P368_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial ribosomal subunit protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_340365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P368"/>
    <dbReference type="OrthoDB" id="283424at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039848">
        <property type="entry name" value="Ribosomal_mS35_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="2">
        <location>
            <begin position="157"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="341" mass="39386" checksum="06792AE2DEE58AAD" modified="2020-06-17" version="1">MCARREHRDEDDEDAGDAGEMSLRAVFESENKASKEIWPDKMSQLEALEELGLADLRYKTLDDADALQDELQAQLPAIRRQVDQLYPTRADARPQKVDDFWHEGDQLEPGDEFEDDAFDHDDISSLAHGELERQREVRELMRVAAWEMPLLGKLAKEFQPPTAAEPLRFRYTTYLGEEHPAARKIVVEFCPGDLPDLTRVQRDKLIKLCGARYNPQTEIVRMSSDAFETAAQNKRYLGDMVLSLLREARDPADTFEDVPFDFRHHKPKLWHAFPKQWLMTEERKKELDQRRTQRYLAEVERIEKGTLVDGARIVAKHMKQTAAAPEPSLMEMVGQRRLGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P436</accession>
    <name>A0A6A6P436_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_341369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P436"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="7820" checksum="EDF147FF3ED1E392" modified="2020-06-17" version="1">MYTPPAQPSTAIRTSGEQSPLPPRAPPQASCPAGRPHKHTRNVYRAQTQARKARAPQQLDGTLYLCRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P463</accession>
    <name>A0A6A6P463_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_341281</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P463"/>
    <dbReference type="OrthoDB" id="1729737at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="298"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1022" mass="110476" checksum="C6A4231E1D997011" modified="2020-06-17" version="1">MLFQSHNRQNVERCGFYYISPCPSPFGSPKRTYLPQVALQSHTRVLSTASRTHLTQTFVNPSKDKGIKEVRYMFPLVDGVSVVGFSCKVEDRVIKGVVKEKEKARQDYQDAVASGQTAGLLEQLPDASDVFTTTIGNVPPGAALVAEITYLGELKHDAEVDGIRFTIPTAIAPRYGSYPGDLTQSDATPARGEAIKITVDAIMAENSFIKEMQSPSHPIAVSMGATSDVPDAHPQMHKASARLSLGEAGLDKDFVLQIVAKDSGVPKAILETHPTIPNQRALMTTLVPKFALPSEKPEIVFICDRSGSMNGKIETVISALEVFLKSLPVGVKFNICSFGSRHSFLWKTSKTYSQSSLNEAIRHVKRFKADYGGTEMLEPLRDTIKHRYSDMPLEVMLLTDGEIWNQAELFSHLNEQVLEAKQPIRVFTLGIGTFVSHALIEGIARSGNGFSQAVLEGEKLDSKVVRMLKGALSPHITDYTLEIQYGDDSTTDDDFDIVEKVSDCLKVNLNTTDDDKASKGKKPISLFDDSIDLDKKEQSPAVDHDGQGRYSHLPPLAPPKLLQAPHKIPPLFPFTRTTVYVLLSPETAQKKPKSALLRASSPHGPLELEVPIQVAETPSEMIHQLAAKKAVQDLEEGRGWITEARDESGQLVKEEMPGRFDEMVEREAVRLGVQFQVGGKWCSFVAVEANAPKPKDRDGDESMTEVEGFEFLDEEKDSAGAAGNSEAFGVPTGSARSRSRRGFSGMPILPPGSATSQAASGSGGGGVFGAIAAAGSSPFPQQARATPTGAPPSPPSGTPVSANFTVPPIKHAKRGKSKKALVGSLFGLGGGGSSFGGSSFASGSGLFQQFGSAQPVSSLLWPPDQMMQATEPQSVAILASAQQEMQGAPMRHSPKVARGFYDPTIENKDSSGEDEDEGEEKVKGNELMALIGLQTFEGSWELDKALLKIVGMNKDAAEAVCKKERLDKKLFATCLAVVFLRKKLAAEKDSWELVVDKAVGWLQMGFDAAANQKGFEKAEMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4J9</accession>
    <name>A0A6A6P4J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_198008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4J9"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="159"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="314" mass="36060" checksum="7F321B1DE059CAF2" modified="2020-06-17" version="1">MSAPTYKLRRAEYSDNSDIPAVTKVISQAFKDDAVFGHMMHPHRFWFKRDFKGFFGRHLGINWWNWTHVLIIVTTSTPKGERIVGVADWERHGKHAREAGFGLAWWDPQNLIAPSISTANSALGFFIWPNRARNPSIPLGVVDSAYTFNHLWPDYDIIDKWHLKVLAVHPLHRRKGVGEMLLDWGLRAADRENGFMTVDGDSTMFEHVVEDIMEGTWVSAVSPEYTMDFFKAFGFSEGFIWSPKGVGQDMWHVSSGAVMLRAPNARVSRRRNTRPVALPRGTEGSDSQRQVAWRCLFEACFDTEQGYQWRVYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4V3</accession>
    <name>A0A6A6P4V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-dependent phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_283899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4V3"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="312" mass="35488" checksum="3E3C50709DD4705C" modified="2020-06-17" version="1">MARQYKDVRFLIMSDTHGMRSDYGDREHPFAKANANAKANVLLHCGDLTKEGTPRQIQAAIRLLKDTAPSAELRLVIPGNHENTLDRHFWVNEWGGDPAEHEEAKAIVKYETENDRRGFHLLDEGVHMFTLRSGATFTIYASPRTPVGFTRSGAFQYNRSIIREYPDGPDIVMTHTPPEHILDSKLPRGRSTGCHHLRNAITRAKPALHCFGHIHKSYGAQRVSYLSANGEEYLQGSYFVGDDWNDEMKVFPKEVIDMEAAKQRGWAQVSDEAMRRVQGGRETLMVNAALLEEDRKNFRPPFVVDLKLPVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P504</accession>
    <name>A0A6A6P504_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NECAP PHear domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_282934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P504"/>
    <dbReference type="OrthoDB" id="10265489at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000465">
        <property type="entry name" value="Adaptin ear-binding coat-associated protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="18"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="33577" checksum="4F1238F8B8F87452" modified="2020-06-17" version="1">MDVVTDPATGRPLPPETIQRVLFIVPKVHIYNIPPLASTKGYSAASWTANNNERLIFTARLRILETALPPEQQLPSSSALPAGVAPGGERITITILLEDPSSGALFAAAPYAHPAAVAQAIDSSRFFAVRVVGDGGRKATLGVGFEERSDAFDFSIALQDARRVLGLEEQPAGAGASSGGASSGGRRGAGAAQEKEAEKRDFRLKEGETITVNIGDRGRRSGSGSLGAGAADSSSVEDANTALFSIKPPPSSSASEGGNAPFLPPPPSASEVRAERRRGRREEQPAQSQPTQPRPTQPQPTQLQPSASDLGFDDGEFGEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5F1</accession>
    <name>A0A6A6P5F1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5F1"/>
    <dbReference type="OrthoDB" id="5389296at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="597" mass="64944" checksum="1529BCE06C2438E5" modified="2020-06-17" version="1">MAPTPDPRPVTPRHRFLLPRARPTPTNPQRFPNNPQSSDVNASSASRPHSSHLHQTVTPARRTAFLPPPLLTVKAPGALQSCGDQFARTPRFNLSANQQRPRIEEAGKQFAKAPRFIPSPSRQRSNIEEAGSDDELAIERKRNGVPREADVDGDSCRDAQDARLAFGLAVRKSIDSGLLIQGGRKTTAQEEIEEISGGEEWTGHEALRDFPRLTDGREDAFGFDEVSEQIDEDRIDQGEGGEDTWADDDGDLPALHNAETDEQLKEVEELASEFHESEYAQDIDGKEGFEEDEGDGYEDDMGKQVEGLTTSALDTDESAPRPTKRQRVLSASPPNPHPSSHLSPQPRHATPPPSHRRFICPISAHAEGTAAGPRGSTFHLNTPVASSRLDASTGAPLPLLATRPPFLRPFGPASSTSGHLSSDELAPPSEIDAAPPRDLHPLPTFFSPQRRGQKYVAGGMAASMRGWVLDIAQQISTEHQGRCEHVSSTVVGFEVEDVGGRGFSSGNGSGSGKDFVLISGKRCQGDQERKKVILIGPGVRSGRGLDVTGYQRKPVSRGDLLKVRNPRWEVDMGEELGKWLVGIEWSTGPLDAEDHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5K1</accession>
    <name>A0A6A6P5K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_187622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5K1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="247" mass="27171" checksum="9FDED52DC4B4189F" modified="2020-06-17" version="1">MAFECNCRAADPCAWYGVVWICRVVRNTQAEVCACPQYLDRFACNLRPWVTSGGIGTAQGSEEQDARSRDGDRDALTSWGMFGEAGPHSPLRRARGGAAAPSNAPSPGSHTRSPRAGESTSVALHHPRGLLLRQCMPQHHSRALPFANLPFYFAAALSHAICSWATPGCCLQRDCRTTTRGSRLRAPLLAGATRRRLRPRCRSPAHPREPPGDLSRVWPLSTLKTALHRAWVPRIRYCIKGARVRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5K8</accession>
    <name>A0A6A6P5K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5K8"/>
    <dbReference type="OrthoDB" id="3904016at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="726" mass="76698" checksum="833F94C83551B866" modified="2020-06-17" version="1">MIVQYHSSPHSHLPLHQSITLKTLQQDQVYLSVALSRAHVLHRSLLLKLDDVERKLGANANNNHNNKSGSRNENGAAGTTPKGSKDSVNEIPLGLTRAKKKSLQQTRWRTRKTLESCAREEQILLSNLSACEEQIEVVQQQQQQQHHYHHQQQQLQPQSRLPPPSPFFLPSPRPQLFIQTQLPPAPALVPVPTPTSTTSTGASAAAAKTANWKALSALSPSWLGDCRCHNCGESLWWLPSPPPAPAAPQQELQAEDQQDQHQQGAGCGCGVRGAGGGTTTAIASTADGARRSQLFQPGPGPGPGPGAGAGAGTGAGTEGAGRPQRQRAAAAGVGSVQVRAQTGQTPAAAGADSIWRRVSDDDDGGEGGSGILDADCMGKAGAGGAAASWGGSGHGDAGGDACANGSGKGSGAVLYSEREKEQQQQQQQQQQWYLVGNVAQQRHAGGTGTVGPAGAALPMAGAAAGAASYHHHHHHHHQASQTGPMQLVHALPTAGLAPGNCGTANAAAGWAPHHRRHQQPYYEPYYPYYYLYRQHQQHQHQRDTAHVGLASETAGIGVTTGASTGAADRELGRGPSVSTAALAANAIVPPPPSPPPPPRERRRRSSFHGGSTGDGAGPGQARSRSEPRTPAAAGEGSGDGDGREKVREWDDLASHWERWIGLRGRVGWQRGEHGAGKRGSLTRVKEDEEERVRVEKEDEDEDEEEEEEEEVDPLTRPRRGPEGASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5S3</accession>
    <name>A0A6A6P5S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_188912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5S3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="183" mass="20095" checksum="99C5202DA178C895" modified="2020-06-17" version="1">MVVVELTYTKSASTGRPRSNSRSEVRKRSTCRPGKGRAKHDATHSQPEPRRKGRNRRKSVEQAGQEMWKQKRIGYNCWGDGLSRGPGTLSANKRKAPPRVTKGHPLPATSRSGPSSRHPMLARSHHFAATRASAATERNQVPPRRRTTPPPPKPGVSRARTGSWPSGFAAADPIAWAFGLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5U6</accession>
    <name>A0A6A6P5U6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_341394</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5U6"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="41"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="60133" checksum="28252BA3FFC5010D" modified="2020-06-17" version="1">MGVKDHPHTHGVADPVLTRIVEQDKVPWYKKKNLRVLYLLLFPACMGGELTSGFDSQNLNAVQIVDAWQEYFDPSDSLLGFIGASYSLGSIISLPFIPLINDRFGRRWTILLASIVMCIGAIIQGCANGAAMYIVARVLLGFGIPPVVVAGSSLIGELSYPKERPIMTSLFNVTWFVGSILGAAITFGTMQLGTNWGWRIPCLLQMWPSAMQILFIFTIPESPRFLISKDRHEEAHKILAKYHAEGDMESEFVRAEMAQIQSTLEIELEFSKRSWWEMVRAPGMRRRTIIASFLGLFTQWSGNTLISYYLNELLEIIGITDANAKGHINIANTCWSLFNGVIISLLVRRFRRRVMYMTCAISLLCVYVGWTITMERVLATGNSAVANAVLFWIFAYSPCYNIGYNALTYTFLVELFPFAQRARGITIFQFFGKCAGFFTTYVNPIGLNRITWKWLLTYCCWLAFEIVFIYFLFPETGGRTLEELAFLFEGKDRADKVTMVVEKQIHHEDNMGVTTMEIDKEKGTTTKVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P682</accession>
    <name>A0A6A6P682_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_259341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P682"/>
    <dbReference type="OrthoDB" id="435520at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="52"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="427" mass="45808" checksum="950529E2BF3BDC49" modified="2020-06-17" version="1" fragment="single">PAISERPSSADSIDMAVEAFLTHPRLSQKVRHPQTGRIISFSDVGDPKGYAVFCCVGMGLTRYVTAFYDELATSLKLRLITPDRPGVGESEAYPDGEGTPLSWPDDVLAICQALKITKFSLLAHSAGAIYALATALRLPQHIRGRVHLLAPWIPPSQMSPIGIHADAVPAGQLPRSQRFLRVLPTPFLKVANSGFMSATSASITRSVPKSPQNSASKKRKTGGNSPAANGGGAKSIPMDVAAPAPYNARRESILMMDRIAPSNSSLAVQDPHDPSHTGGGLGGGPWVDGPAALAAPTPSAAATPYHLSSPDRRARYDARLTSQTWDLATTHANPAVDLLVCLERHAPIGFRYVDITRAVVIHHGARDSRVPVDNVKWLGRTMRRCEVRILEGEGHGLMASAKVMANVLQEMSKEWEDWTAVVQGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P775</accession>
    <name>A0A6A6P775_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_178446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P775"/>
    <dbReference type="OrthoDB" id="3518533at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025599649" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="38"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="211" mass="22821" checksum="1E9211BFC8B998ED" modified="2020-06-17" version="1">MFSFALPLALLGSATLVLSFPSSPVFPRDGPSLSHAPNFKLTAHVTGTDLNPSIEGWVLSGSHIMPCYSWVILEDPTNSPGRIFYENGTAEEIRYNAGAVLSDGGSPPWPWSFIVPDEENEDHGRGVQVNCGAPTKGVYLPQFPDQDPVLRYGGGRFYACDADILYGPRVTLFYRDAEAETPSGCAEIDLVPHCVMDGAQHNFTVPAPCFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7H3</accession>
    <name>A0A6A6P7H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_181884</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7H3"/>
    <dbReference type="OrthoDB" id="3364175at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000005">
        <property type="entry name" value="Quinic acid utilization activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF2">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="11">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="141"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="193"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="878" mass="97593" checksum="ED9B984F0E723533" modified="2020-06-17" version="1">MAEPGKRKAARTPDVEHGARPNSSTKRQRVSQACDQCRTAREKCDGIRPACSTCASSSRACSYAANPKKRGIQSGYIKVLEEALAWLFCNSRGCEEALRFALTTGDHDHPVRFRHTEPEVEAKDLHTVWRKSRFRTEVDRLLSGDSANGPPSLPDDGPVRFIGPHRSRDAPQNSIGPDSTAPAQLIDRLETVHSPRLSHPGLVYSESAGTSSTNRPICYSTAEPTSAGGTYTELSRGQKEASNGFACPDTGESLPPDSTSKGSSIPQNTRSQSNTAMYHSSGNSEDKQPFKFQAEASAPWRTRPQRPQTLKLPSNFWRLLDVYFAYTHSWFPIIDKQEVLKASYSYHERGLEHLSGARDQASHAQLWSVMALAAFQDDAGGASDASGAEQPANVSPHMILDTARQLIPSEDGCFEIGHAGALLLISLAYIGQNEYMTAWILVGKAVRVALPRKCANQTPDEGFHSNHPRRRLMLFGCFVVDTVLSAYHGCKRHLSRRDMHLLGILDEEGLEEWHPWQGCEGFGSDKSHSTQHLVKAPVHSLSIFNNLVHLVGILGDFSIRKIRNWHPQPTQDLIHELRSWELNLPEPMRFVGEGNIEDAYTPPSLNLFFTYNVLRLILGGHKDLFAARQIVNSLELHNRRFGLLTTPCLARLLIFIVKEAGCFDTLEPTEMRILETSLSEMAFSHRTGPSDEPQCHTLSRERLDGHGNYVLKEMSYGGVGKTGDEASNNSRIGFPHTRSSVWNSVFGDNRMQTTPHQDPWQWNTPGFPSLHNPLSENPHFTDEPSFIDRESYPLPHTDMDLAMSSSASFGRESTVDRSLGRVDSIDLEALSRDLASLESAESTQSQPEFMQNLGFAPNMNLNDISNEGYGYLDAIFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7T0</accession>
    <name>A0A6A6P7T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_299296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7T0"/>
    <dbReference type="OrthoDB" id="540662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.110:FF:000003">
        <property type="entry name" value="Pre-mRNA splicing factor, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000698">
        <property type="entry name" value="Putative pre-mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="5">
        <location>
            <begin position="67"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="300"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="342"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="384"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="491"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="530" mass="56942" checksum="2577584C1C174879" modified="2020-06-17" version="1">MMHPSRQAYVEEEKEDEETGVDLASLPIDHDYNVPATGGAGVAPERASAILSQFQRKRLAASIAVPTDDNRVRARLRSIGEPITLFGEGPPERRDRLRELLTLQAEAAAGLDGEGDHEMGEAAAGEDASMADAGAEGDEGDEEFYTEGTEDLLRARRDMARYSLPRAAHRVAFQKQESTIPLRVHVKHRKGIKERLAGFELYGSQIAADRPVSITRFAPDGQTVAAGSWGGSLKLLGVPDLEQRMLFRGHTDRVGGVAWYPGATLPESGVTPSAINLASSGGEGAVHLWSLEQDTPISTLSGHSGRVCRVEFHPSGCYLASASFDTTWRLWDVATTTELLLQEGHSRECYTVAFSPDGSLLASGGLDSYGRVWDLRSGRLVMHLDSHVGPVYALDWAPDGFRVASGSADGFAKCWDLRAVREAGALGANKGGVTDLRWFKGTDGPASGRPPPRDDDGNVLPKKAGTFLVSCGFDKKVNVWSADDWALCRSLGGHAGNVLSADVSADSKWVVSGGHDRTVKLWARDDGEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7X8</accession>
    <name>A0A6A6P7X8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_413698</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7X8"/>
    <dbReference type="OrthoDB" id="1937997at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="214"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2459862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="439" mass="49068" checksum="166BEBB0CB34ECC0" modified="2020-06-17" version="1">MPSATGQNWEKYQKTYADDEEPEKKITPLSDEDIQVLKTYGAAPYAAELKKLEKEIKDKQTSVNEKIGVKESDTGLAPPHLWDIAADRQRMSEEQPLQVARCTKIIQDEKDSDKSKYVINVKQIAKFVVNLGERVSPTDIEEGMRVGVDRNKYQILLPLPPKIDPSVTMMTVEDKPDVTYGDVGGCKDQIEKLREVVEMPLLSPERFVNLGIDPPKGALLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEVDAIGGARFDDGAGGDNEVQRTMLELITQLDGFDSRGNIKVMFATNRPSTLDPALMRPGRIDRKIEFSLPDMEGRANILRIHAKSMSVERDIRWELISRLCPNSTGAELRSVATEAGMFAIRARRKVATEKDFLAAVDKVIKGNLKFNSTATYMQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P808</accession>
    <name>A0A6A6P808_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription factor Nrm1/Whi5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_192859</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P808"/>
    <dbReference type="OrthoDB" id="2163387at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468:SF1">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468">
        <property type="entry name" value="YALI0A15257P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="215"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="275"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="392"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="45844" checksum="2275C436AFF9D867" modified="2020-06-17" version="1">MASSAKSQDQPAEVASKVLRRAQVSKMTRALQNRLALANVKIKHGWQNLSLETIEPRVEMELKRKRPGSSNETMSDTSSSCISDRLYPVGVLESSPLAPPIFSDDVARANGHHGSKRTKYYSHAAAAAARQPASSSHARAKVRHHHNGRGSWKSAYRLPESSPAYHARRARYPHSSHVPSLSFVSEASTVPDDPVSPVTTDDEDVELPVHSFQADAPHFCSSPPRTPRTPPPGSRSGRSAGARSASRAFNAHGQQRNGQSGEEGADLLLYLATSPSPAHHNRNANNDGGNNPSSASKTPTTAKQRLFAPSTPPPKSTPLPSSMMSTPGGGMSSFPGFGPNTPSAAAFNYTDFLNFTPSPGQAVWKTPVAAAKTPLAGGKEAARRRLNFDGLLPSSSASGGSPNVGGSGSFESKTSTGSTKKETGLGMELGGELVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8J2</accession>
    <name>A0A6A6P8J2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_184483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8J2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21676" checksum="C81C358B0BC13628" modified="2020-06-17" version="1">MRRRSSPPAIPSCCSAAALNQSPSRSRSHHQESLLAPSPSNAVGTVPRRHFAQRLPRRARQRGGPPQKPERAANRRVARPVLARAPKPSSGTTCSFQHLGKRVLGQNSFSFFSLQGAATGRSGHTVDFFLTAHDSTRSPWHPKIHSAVLRLLKSRFPSPIYIAIQRRPFGQYAILKHQGVCLVHPLWNFGRLTGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Q2</accession>
    <name>A0A6A6P8Q2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_280657</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Q2"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="66"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="342" mass="38280" checksum="655A5136D4133BF9" modified="2020-06-17" version="1">MSSGFQAQPGWEWPSGLPGRFDSAAFGQESEDESGSDSHSFKTTTGGSASPRHGQQEHQQSQPRPRRFYRPRTCRICLETVNPTFHPEADNTQGIFGHSMPNVTYESEDGGRLLRPCKCKGSSRYVHEGCLQAWRHADPAYGKRNYWQCPTCGFRYRLERMAWGRIVSSAAAQVVLTLFIFFVVTFLLGFVADPIINLWVDPLGTLSPFLDEEERVPLFDDEPSTWIEHFVKGMASLGLMGFAKVILMSPFHWLNLRSARMVPGGRVGVTGRDRMANLSWVTITIGVATFLYGIWKSVRNWSRQTLEHAGERVMDVQADDEDDDDENEGDENSGFGNVGGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Q9</accession>
    <name>A0A6A6P8Q9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_281179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Q9"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="461"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1238" mass="139634" checksum="7C25B719AA15ED02" modified="2020-06-17" version="1">MRRQHNPTLGRGLGRGRGRGLGRGNSAASHARSSSGNANAAYPDAPNAPWRSWPEVCVSVRSLPPSTTTDDVLRIFSAYGDIGYISISPPTGRYPDAAAKVIYRPPPSTAVWMEPIRMGSRILRMFLAGEQKTEDKLIKSPVHPNTFYPEEMKKNALSVEFGQTPVQGTFLSMRKILPTSTNQESPLRFQLDLRKRMLSVWFSLRLGKDEPHEFKFQVPFSGLRKIIQERVGPEKSAITFSVEFPPWYTGKVRSLDKASSDIPSRTWDSGGLWWRVTTIFQLDDKEMLEKSPERLYKPYAFIDPGRWLTWRIQFLDDEQSDTYLQMRAALRDFNINTVQDETLNILYKPDIKFHGLVDFPKLAPNNLHLLTTPEEHIRLTWPVRYQLEVCLSWGYLLEYNLSAEWLRQLAETEPEVATRMLEQVAEEKKKVENPFDIFKHEGLKKRRTPPEYCLHMQSATVTPTTIYFHTPVIEMSNHVLRKYAKYSNRFLRVKFQGEIPDGQYYPPDNNTHIGIFNRFHRVLDNGIAIGDKHFEFLAFGNSQMRTHGAFFFASNENATAAQIRDWIGDFNHLKLVAKYAARLGQGFSTSRAIQGAPTIKIVNIPDIERNGHCFTDGVGKISSFLAMLAAQSLDLPTAEMEPPSLFQFRMGGCKGVVVVDPTLTGIQIQIRPSQNKFSTPNQGLNIIRTSSLATATLNRQIILVLSSLGVPSNIFMFKQKTLLDQLHNIFDDEDLAISLLRANMDAKCTTLKLAAMVADGFLTAKEPFATSMLRLWRAWLIKYLKEKAKIPIEKGAFLLGCVDETATLRGHFKTDRPLPHASREQRMSKVPEIFVQISDVNKKGHYIILEGICLVARNPSLHAGDIRVVRAVNKPELKHLKDVVVFPQTGDQPLANMCSGGDLDGDDYLVIWDPELIPMQINYEPMDFSPPKPTEVKDKVTVSDVTDFFIKYMCNNKLGQIANAHVAHADRSPKGVKSAICEDLAKLHSIAVDFPKTGVPAKMGPDHRVATWPHYMNRKGPSYHSESTVGQLYDMVRCVDFQATDNCAFDARLLSAYVPDADLEAFCIRLKRDYDAALRRVMTQFEIATEFELWSSFIIAHNGHDYKIHEEVGSIVDAIKETFRASCWERVGGSPRYDGGDAERLRPLLLALYKVTADEVTAAVKGCTVGSEDNKDPACRPLMSVAWLFPNELGAVAKSSWMEKDRMARALMEVMKPVGRGVGTGGLVKHTEILNLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8R6</accession>
    <name>A0A6A6P8R6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8R6"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="NmrA-like" evidence="2">
        <location>
            <begin position="40"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="354" mass="38466" checksum="61FAD5BA1DA2DF43" modified="2020-06-17" version="1">MTSPTFALTATTGKLSSSILSHILNSSLLPPSSLILCTSTGSPTHPHLSAAVSRGAQVRRADYDDPASLEAAFAGVDRLILVSTPAIALDFNEAPEGQGRERQHYAALEAARKVGVKHVYYTSLAFACGGKSESKAGVMVAHLRTEARLQQLAREGSIQFTSIREGLYSESWPLYFGHWDLGKDNNGRSEVKVAGDGKITWTALSDVALGTALIATDKDSAKWEGCKVTLAASKGGITLAEMAEMVGKRLGREIKFEVVDKEEHVKYYVNQRGMDEPFVRWWIIVIALSFLVSVVTKIALPLFGENNIIAIAHSSSCVLFSSSSSSADDFRYTRLFKVRSRTTLLWTIQESSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA34</accession>
    <name>A0A6A6PA34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA34"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="20177" checksum="E4D9B7EFC4B1578C" modified="2020-06-17" version="1">MARNVVQSIPTAAGVPADPRGPAAPRELKFFSRPRGLGKTTRADSLASAPIKMGCGWSSCRRPSWRWPSWRRCWSPCRSASSSSMSSGSSHFSWGDDCCLPPIRRASRPVVQVPGLETIREETESDEAVPRLVSNGSTAPPAPAEAVEAAETETAGAEAGSDSGSVPSSERRKASRRLGKLKKKLRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA98</accession>
    <name>A0A6A6PA98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_402867</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA98"/>
    <dbReference type="OrthoDB" id="5783963at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="51809" checksum="D8EAAF2C8E120AE6" modified="2020-06-17" version="1">MAPNRIIIDTDPGIDDVMAMLLALSAAPEELEVLMISVTWGNVEVQNCLRNVMSLFHHIAKEQEWRRANGQPEGFETLKKCKPIVAVGADRPLEDQRMMADYFHGVDGLAGIYTSHPHLTPAETWANLFASALSSNNPDLVAAAREAASSSSSTAANAPTSHALFTPTNQPAHEAILSQLRAHPADTITLVAVGPLTNLALAAAADPHAFLRAKQVVVMGGAVDEVGNITPVAEFNTFADAVAAARVYALTSPRPASTMPPAPPPAPAAKTDGHEPPSRSSQCLPPYPKGLGSRRLKVVLFSLDITTPHEITRGMFLSTVKPLVSAGSPLAEWVSAFVTPTFAKMEALHVGAADRSPDDVGLALHDPLCIWYALLHEKHPEQWKMAAGAPEDIRVETAGQWTRGMCVVDRRDRKRREEPTVEARAEVEEGDEKEEEPEVHNDTGNWLGSKGGNRIWRVVGTPGHNVWGPYLLKRIFQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAN5</accession>
    <name>A0A6A6PAN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative importin 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_333905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAN5"/>
    <dbReference type="OrthoDB" id="431626at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056840">
        <property type="entry name" value="HEAT_IPO9_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF9">
        <property type="entry name" value="IMPORTIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25018">
        <property type="entry name" value="HEAT_IPO9_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin-9 central HEAT repeats" evidence="3">
        <location>
            <begin position="207"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="810"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="818"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="902" mass="98702" checksum="0D5818B74C47014C" modified="2020-06-17" version="1">MEEGFSDETFYGVVRDLVKTMYDVSVNADNKPTIRALAVSVFRGSLNTLETVMEERKAAVKQFADEALSVWIPFFIEVLESRLPPPPPEDEENQDGGASEIFRGLVVLKIQVVKVLMRMRSVFPSTLSPHSPALFSATWNELSALQEPYHLMYIEEERQSRLEDADHLPYTLDFLVLEELDFMQACLRASPVRKELEQQLSGHASAEGTWVTQVMKVAVAYAQITTEEEGVWNLDVNIFLSEETGVTANYTPRTACGDLVIKLGEWLEDYTVDGLLSYSRSLYSTGHSWKAKEAALYILNQLLGDLADMQRCIKPEAAEGFIEFIRYAMQQNDEFLRARGHLVAGSLIKASDGNLQAVAAQFMEASLRAITTDESEVVKVSCIRALQPYLPAAPANITMPLQPTIIAALAAFLSTQDVSDMAESDDLMVTLVNTLKSAILLNTQICIAPDEDTAMGPNGEPHAGAQGALNLLFTLASHGANNFQLTMLVNETFEDVARSIAASGYDAYVRLCEKVLPGLSGAFDVGALTDESALTSLAADLLSTLAEYGSEPLPQGFVAASMPKLNRLLLGSSDGQLLRAATVAAQNIIAHDHKQLFEWQDPETHKGGLEVMLVIIDRLLSPSVEDAAAANVGGLAAEVVEKAGRERLGPYLEQLLRAVAVRVGSATQAAFIQSLIFVFVRLSIVSPHEVVEFLAQVEMQGGESGLAVVMRKWLENSVNFAGYDEIRQNVIALSKLYDLQDPRLAQIQVKGDLIVPQSDRIMTRSRTLQNPDQYTVVSAQLKIMKVLVDELLSAAGGGPQGMAARSGLAAAQQMAAEEAAEEDEDDDDEWEDDLDTLDLGLGVTKRDLMSYDQPNSAFGRAPDDETQAYLVNFFREQSAKPGFGEMFAALSQTEQDKLRSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAV0</accession>
    <name>A0A6A6PAV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_137490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAV0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025609499" evidence="2">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="16897" checksum="85926F32A1179495" modified="2020-06-17" version="1">MQIKFALLAAAGLLVSVNAAPTPKRQVSTIEFGDDPSSTMTWSHDGEKSSGTSSISWGPKKRAPQGEISETLPNGGKISFGDWDSTTWFENAPKPPQPGSGSWISWDPSGKEKKARRGDDGGISDGTATLSGFESETVWESDAEAKPGSSFTFDPSEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAZ1</accession>
    <name>A0A6A6PAZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WD40-repeat-containing domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_376786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAZ1"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34366" checksum="BD1347DABDF41B1A" modified="2020-06-17" version="1" fragment="single">MDEQVDQVSSPAVSHSFARLVAHTRDVYCRSVAETTKVEILLNGQKPPHSSQPNKWATNHFISLQWTSSGAFLLSANADNILRTFAFPTDNLMSKSCGFLRPMAAHPFPQNMYAIAACSWTEDHATAVVSVADIPLQLIDFYPDGSTKIVGSFVMWRLPGEDLLKAYSLAWDSDRNYLIAGLKSCVAIADPADPQAKPTYIRTCPMRKARGYSPSVVHGLVHALSSCPTERNVFAIGTTGRGLALADRRQRDLATAVKVVDDPLNWGITGNGITSINWDSHGQYLLVSERHSDGIQLWDLRYQGRCLAYLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAZ7</accession>
    <name>A0A6A6PAZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Magnesium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_333786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane magnesium transporter (TC 1.A.67) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAZ7"/>
    <dbReference type="OrthoDB" id="44756at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053279">
        <property type="entry name" value="EMC_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018937">
        <property type="entry name" value="MMgT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28144">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28144:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10270">
        <property type="entry name" value="MMgT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025618582" evidence="8">
        <location>
            <begin position="23"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="144" mass="15784" checksum="EE8AA6BB7FA01281" modified="2020-06-17" version="1">MNPIAGLLNFIGFLLLTHAVYSAHEHSALFANLPPTAAPTGSPAVTSLPTDIVLETLASVVVLCVGIVLASPPLKPIQWRVWAGRIEREERMTPEQKARLGNRRVGGPGTSGNPFRVLEERMGFWDVRSKRKEFADWVREGGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB18</accession>
    <name>A0A6A6PB18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_315193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB18"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="37735" checksum="AB8CD60E1D991A79" modified="2020-06-17" version="1">MPLTHTEYGVHTEAATAAAAFASQIKGKIILITGVNSKGIGGETALALAAYEPKLLIAAGRTSTKVEEALKPIKDQHPGTPCKIVTLDLSSQKSCREAAKEILDSADVPQIDIVINNAGIMWLPERRLSPEGIELQFATNHIGHYLFTNLIMPKIIALAKASPKGGTRIVNVSSRGVVYSPIRFSDWNHTKTFEELPESERPPIEVVTEFHGGKVGAYTPIVAYGQSKTANVLFSVQLNKSLYDAYGILSIALHPGHVMTELGRYIPPEEMALVAERARSSGIELKSPSEGASTQIVAALDPNLGPEDFFLAECRPGDWLPKWGSDPTSAEKLWKLSESLVGEEFQWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB55</accession>
    <name>A0A6A6PB55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_361160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB55"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="273"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="471" mass="51787" checksum="AD7378940A8B398B" modified="2020-06-17" version="1">MRDNSDVPQPGPARLSKGAGPDEWLEQAKQCKYLPEADMKRLCEIVKECLMEARPYRHNKTQINQPPHISESNIQPVRTPVTVCGDIHGQFYDLLELFRVAGGMPADAPPATAPPPLSTDPSSSPIPSPSSASSAVKQPPTSPPPQGKIISAADIEPPTQITDPRAKRKMKRRFQRDANYTGPAPGDGEEDEEDDIDDEGGRGRSRSIGRRLSSMDDEGEGSIVGNPAGGAAGNGMQNYIFLGDFVDRGYFSLETFTLLMCLKAKFPDRVTLVRGNHESRQITQVYGFYEECQTKYGNASVWKACCQVFDFLALAAIVDGKVLCVHGGLSPEIRTLDQIRVVARAQEIPHEGAFCDLVWSDPEEVDTWAVSPRGAGWLFGDKVSSEFNHVNGLQLIARAHQLVNEGYKYHFKDKDVVTVWSAPNYCYRCGNVASIMSLDESLDPEFTIFSAVPDHRRAVPAGRGGRGEYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBA9</accession>
    <name>A0A6A6PBA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Docking domain of Afi1 for Arf3 in vesicle trafficking-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_331497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBA9"/>
    <dbReference type="OrthoDB" id="66409at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08616">
        <property type="entry name" value="SPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="1"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="827" mass="90097" checksum="513CB967D3E9EF67" modified="2020-06-17" version="1">MEHQYPGPISGDEHMLAELMLPDQAHVRSQDWTIFFLHKDTAAEEEAREERREKRRETRERRKWRRKARMVMEARRRRRRMEAGESGVGENGRGSEDEDDVDALSDIEDMLGGDEDGLHNGENGPFEDESDSDSDTEAEEEEQLEGPPLIYVLNLVNTKQDNTVKRGAVVKAMAICTRHSFLHIYKPLLLLALEEYFKAPVPETLESLYNALNSMDLSLMPRLSLLERFILQASDAKDMFIEKFEQMIQQRMAEDAERRSMLSSNSSQQSPSRPSTQKYALPRDTHEFESKVLYNGIPVPIKVPTAISPETVGDFSIVKLIQTFSNPHASSPQPFALHPHLTTSGAFTHPIIVLVNALLTQKRIMFLGHNRPSGEVAEAVLAACALASGGLLRGFTRHAFPYTDLTKIDDLLKVPGFIAGVTNPAFANKAEWWDLLCDLPTGRMKISHRIESAPVTDGLLYFQQHHLPGLGTGTASGAGGSGHLYNFPHHGIGGGSTKGGGGSGGSSSNSGPGGVGADADVTGDNAFMESLLHSISQRHGEGVIRAKWRDWVLKFTRIAAAFEELVYGASALYIGALECDSDAGGYGVGGHGYVWPDDAARTRELAGNVYRVEGWRNSRSYYSFVQDCAHLWTKRPVRDLDFAHHHDRLRFLRLSHDQSAAVYLAFARAVDEAGDRAEAAAAAAMVASTTSPASAEGPSAVSQPQQLSQRALDRLHAQARYDVVNQLLTSVPEASNAGLFYVALGLFHPKPEARAAVVRLMDAIIAHPAGRHYWAALGRFAKLAYLRIKQGGSGEMGPQGLGGGSGGAAMTSGGAAVTSAGAGGSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBF8</accession>
    <name>A0A6A6PBF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_279662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBF8"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF127">
        <property type="entry name" value="HISTIDINE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025351987" evidence="4">
        <location>
            <begin position="20"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="551"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="637" mass="66590" checksum="89DBB330B166F876" modified="2020-06-17" version="1">MLAFFVALLAAVILAPTAAEPGKRQVDYHNVRASVVYTVAGEATPASLGSFGPQHLTSLGAQQLFAAGSFFRQRYLVNDDDGPTDGTTDEAYRPIAGLSADIVNDDHLYALTTDDQPNVASAQAFLQGLYPPFEIAGSDAAATATQLDPSSVLSNGSYVSSPLDGYRYPRIRAASTLDPAYASVAGNRQCGAWAASAQVHLASEAFTEVANAAADLYYDVGTALLYDVLDDSGWDYINAVPIWDYLSYMYNHNSTVMSLLSSNISFPGALDQVRDLASRREWAINADLAYSSVATGAQVGEQIRAVAGKTLAAKVLGLFSEAIASGGDTNKLNLLFGDHAPLTAFFGLARMQQADADFYGLPEPGSSLVFDLFTTDDAADAPFPTSDEADSLKVRVYFRNGTAPTADPDDDGIRDVQNSVLTARTLFGNYAVDFAWDDFGRDMAAVMTPSAAHWCAACGGTALFCPAFSYAGLADDEEARRTDGCVSPPVAGVIGVVVTLVVLAIVAALLALLLGVRVRRVPPPPPAAAKKSFGGFKGDAKMASDADLALPKGGAPAGAGAPAPRGPLGDVKGHERVGSWELSGPGDKDVEGGGPGADAGAMGMSMGVGRAGLERRRSEESLEVSPYAEPVRPEERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM6</accession>
    <name>A0A6A6PBM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_278717</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM6"/>
    <dbReference type="OrthoDB" id="311279at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="89" mass="9900" checksum="5D265D1EAA227ABE" modified="2020-06-17" version="1" fragment="single">LDRLIGLAMLVVATAVFTYYTIWTLLMPFVDEDHPLHSLFPPRVWAIRIPVILILLGSAVVGSFLGVVMIRSNRKKAIKAAKAKAEKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC27</accession>
    <name>A0A6A6PC27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit F</fullName>
            <shortName evidence="4">eIF3f</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_278377</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC27"/>
    <dbReference type="OrthoDB" id="25498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000019">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03005">
        <property type="entry name" value="eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="30"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="314"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="353" mass="38427" checksum="503EDBC819D85902" modified="2020-06-17" version="1">MADTDSFLHVARPLGPAAVGGQPSTAPLNVVIQPQAIFSILDHSLRRNPDQERVIGTLLGVRTEDGTEVEIRNCYAVPHTETAEQVEVDMDYQKQMLALHLRANPREVLVGWYATSSELNTFSALIQNFYGQQGDGTWPHPAVHLTVSTVPGQDIEARTYISAPIGVTAERAADSCLFIPVPHEIKYGEAEKSGLELIAGAKDREDRTQPMVNDLDALEHAIERVLEMLDRVSNYVNNVLDEEATPSNALGQFLMNALALAPKVDPADIERDFNNHIQDVLVVSYLANTIRTHIDISNRLATAALTLGTGDGIGGTSGGGGGEVGQKGDRQDQKRGGGRRGQDRRQQQQKEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCD7</accession>
    <name>A0A6A6PCD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Splicing factor 3a, subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_138546</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCD7"/>
    <dbReference type="OrthoDB" id="10250970at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2690:FF:000002">
        <property type="entry name" value="Splicing factor 3a subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="27374" checksum="584C8A26E16009A3" modified="2020-06-17" version="1">MDYQNRAGSKFGGGGVASKSATNLDRRERLRRLALETIDLDKDPYFFKNHVGTFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAKEEKEGKPRDGQFMPGGQQGVQVKRNVVKIGRPGYNITKRRDPLTRQLGLLFQLHYEEIAEGVVPRVRFMSAFEQKVEEPDKNFQYMVVAAEPYNTCAFKLQAREIDRRDGRFWTWYDEDNKVFWVQLLFKSEGEERYSGAPGSAPSGPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCK9</accession>
    <name>A0A6A6PCK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_279795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCK9"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="65"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="40162" checksum="9DA7CB93CF08D164" modified="2020-06-17" version="1">MVAATSSSPLACPTSFKQRALRGAVADPLRSSSQRSLGGRHQIRTIVGEGGTRHKLNTGAEIPALGIGTWRDADKQEQTVLTALKAGYRHIDTARIYGTEPAVASAIEASGVPRSSIFLTTKLWNNSHAPSDVEPALDASLQDLRTPYVDLYLMHWPSPLQSGPSLRPTDARGAMIPGAADYVDTWRAMEALLRTGKARAIGVSNLAESELRRLLRAARVAPAVHQLELHPWLQQRRFVTLHRRLGIHVTQYSPFGNANPAYAAATEELSPGERLIEDPVLVEIGRKYGKSGAQVALAWGIRQGRSVIPKSVSPERVRHNLEGDFELAEEDLRRIDGLDRALRFNDPSARFRWNYYADLEGKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCP3</accession>
    <name>A0A6A6PCP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GNAT family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCP3"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052777">
        <property type="entry name" value="Acetyltransferase_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43305">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43305:SF1">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="18245" checksum="87801433F33BED19" modified="2020-06-17" version="1">MDSESYRIEPARSSLDIDHVMQLFIAYVEWLGIDLTFQDFEGEKRAMPGKYAPPKGELLLARDRNRRPIGCVALRPMDEEGCCEMKRLYVSPDARGLRLGHALVKAIIDDAASKGYREMKLDSLDKMVQARSLYKKFGFVETSPYYDNPIPGAVFLSCTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD92</accession>
    <name>A0A6A6PD92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor TCF25-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD92"/>
    <dbReference type="OrthoDB" id="205993at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="616" mass="69428" checksum="EEC2E09C253E2B13" modified="2020-06-17" version="1">MSSRALRRAQREKEEQKRLRRASEAEIDGEDGDDDDDNDDDGGPAPATKTSMFAMLDDRDEGDSPDETPGEPTLEEPETPAAGARRKKKRKKKGKRKSSPPRTSNASTQLEEIEQAIRSLDLELRRAWGGETASPRDGDAQPYNLLAIDTQHLQAANEMRRLFGRAALQGAYDDDDDNGGPLGLRRNVFVQGKEEWPRGTSGGLGMEVVERHSDGTTEYRFVHGSAYQDVQRQFLECVAIMDHERMISLLRFNPYHVATLLQVSEIAKQERDHTTSGDLLERALFSFGRAVHSTFAAKLAQGKARLDFASQENREFWLAAWRYVSNLGMRATWRTVFEWARLTLSLDPAGDPYGVCLALDQFALRARQPKAIVDLAESPWFEERWRGLCNVQYSVGLAHVQAGDARLGREKLRSAIEDAPWVAAALFRELNLEPIPPAIWGRKPRSLWETLSTRLYVSSARDLWNTPEATALLSEVASYAKPDSAQVDDRPISDNVARHVLLVDKPELVSLVASSIKGRDLSSFDPLPPPQSLSPYRIERPRPTSREQMQQELDDLTHFFLEQRQLFESAQGDASDEARLHFLAETGISMQTMQERLRRVQELMVQLGGAHRQEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDG3</accession>
    <name>A0A6A6PDG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDG3"/>
    <dbReference type="OrthoDB" id="10274540at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="31125" checksum="DE49F28C3CF8BD34" modified="2020-06-17" version="1">MSSASSDTLHKSSRRPSEPAEPMKPEKTEPVKSEETAPPKPEETVSDETDPKQVVMRATMASASSAKAREQMDERECSRRRAAITRLRLFLYNHFWWIPGFRLSREEALQQVVERDPYTMYLTTEKKDGTKVNLLAKMDTGADGNFIADDLVKELGLWDEVERHGGRKWLTLDGGHLPTIGTIRLKYSAGKRNFPMESDSCTLFHVLEEEREAQDIVLGGPALSEAHCLTIDPAFDVKPRYKVITREPEKGAILCTERGRGAKGKVVFIPKKPGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDG8</accession>
    <name>A0A6A6PDG8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7904 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDG8"/>
    <dbReference type="OrthoDB" id="6375767at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051014">
        <property type="term" value="P:actin filament severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008154">
        <property type="term" value="P:actin polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057226">
        <property type="entry name" value="DUF7904"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF133">
        <property type="entry name" value="DUF4045 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25480">
        <property type="entry name" value="DUF7904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7904" evidence="1">
        <location>
            <begin position="45"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="401" mass="43505" checksum="81B5D720E7C4A994" modified="2020-06-17" version="1">MFADYFDETPVLPEKLSVDTQAVITSSPLDTGKIKTLRKQIQEICDGKVLAVPNHEEHILYENSIYVCTHVFGSSVGARTSEVYLWVGAAVSEAAVEDAQLFAKKAAKESGGKMMLSRQGKETPSFLEALGGILITRRGSPASRSSKYVLCGRRYLGHIAFDEVDFSLASFCSGFPFLVSTGTGSIILWKGVGCTAEELGSARLIGSDLGAAGSYDEVQEGHEPASFLALFTGADPDGPKSMPKSADHWRLKAGSDKFAARLFRVEQHQHQPHHARSLAHQVVEVAPFCQADLEPEGVFVLDAFFEVYIIVGALTRSQHHAFATALLFAQEYGILAASLQDRPFVPVSTVVLEGFPRDLKAVFRRWDDRFVPTSALMAGKPKRGKSLRTVGLDSAIAAAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE22</accession>
    <name>A0A6A6PE22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_10610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE22"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="26475" checksum="BF28DE9E62EDF8D5" modified="2020-06-17" version="1">MSQVDVGVFGSKMCGEGEMKANSSNAERNRPVHERRSEIVLRQQGCGPAPSSVPQSGAGRQGPWLGHLGSRSNVAVQMRGPWWVLPSRPCPGYACERTVGVDADGGGEGAARCSMGLAAAPTNQPSATSVGAVRAGQGRRKGAGIIVWCVAGGQEAVRSALLRAHAPLRRADTTRSRTTRFIIVFKTRFPGRAHHIQQGQASDGAVGTSSQQVARITRCLSLWPSVVRCCFFSCSRRSPGSGLSARRLVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED9</accession>
    <name>A0A6A6PED9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RNA binding protein Nrd1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_12216</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED9"/>
    <dbReference type="OrthoDB" id="79367at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031126">
        <property type="term" value="P:sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16984">
        <property type="entry name" value="CID_Nrd1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000026">
        <property type="entry name" value="RNA binding protein Nrd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000397">
        <property type="entry name" value="RNA binding protein Nrd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048892">
        <property type="entry name" value="Nrd1_Seb1_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21380">
        <property type="entry name" value="Nrd1-Seb1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="8">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="463"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="600"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="72396" checksum="61237BAAD78DCB48" modified="2020-06-17" version="1">MAAVEELGKLLQEMQALKAPGVTKSKIEAITALCITNVQFEASLIQKICLHFRSTPSTHKLGVLYVVDSVTRQWVEKARQTGQELSGSSAAAGTYAAGVYKMTEILPHLMNEMLSVAPDNQKEKIQKLVDIWERGNTFPQQLLAGFKQKLSSVSASVAPQPATAPAAGPPDAASILSALAQLGTQSSSTPTAPTQQTQPDNRYSTNSAIQPLVASSLPAVLQNAGAVAANSSIPWHGMPAQPAQAPAAAANSNPFASLIPPQANQQPAAQQPAPETQGFQVQLVQELLQKQYGPEQIAQIFAALQNAQLPGMAPAPSPAIAPDMTPSMSHNGPGGNGNETYAQHYSEGNRPADHNDAHDYQRHRHRSRSPDYRRRGSPPRNRRDSPTYGAYDPNIAQSANDGRPAEHDRKGRGGRGRGRRDEYRQRSPPPQRSRQGGSPKASGPKWVEFDKSLPSGCIKVLSRTLFVGGVTTSESEVRNIFSRFGKVQTCIVNHDKRHAFVKMIDRHDAVSAKEGMDKIKDQEIIGKVRSTRWGVGFGPRECSDYSTGISIIPINSLTDADRKWVVNAEFGGIGGRPLEPGLVLEEPDIEIGAGVSSKAISRRVGPEGGRRGGHGFSNRGGFDPAAPRYRKPERQAPEPPRQPSPRSEPHIGPPPPVPTFGFQLPTLPGGVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEH4</accession>
    <name>A0A6A6PEH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_9837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEH4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="35201" checksum="5C85F72CB25ED006" modified="2020-06-17" version="1">MKDSSPAKGTPTSVFSCEPSAGDFSFVSPERIQASDEGVSDFDTLTFHSEDWSEMDPLTKEYLQDYDDSSSMDDSTYMSQPDTTGQVPVSGPSGQYGYVDQNPFFEQYMRYSPSQGSDSHGSRQGSQPRPSIVMQSPLIDSPSLADPGLTYTNFSQNSAGAGRPSNFDFQSSQQLSLSGARSLGQGSDVEGRVEDTWTPPEPQSYNNPFMNVEAGWGQFRPQGEYIPEDVGVQLRQPHPLSLRYQQQGGAGSVPVRTQSYPGPQPGQAMMSQDVMRRSSAAVPHGSIDPSTIVSPTGSAIHDSHETVGIFDLADNRHSFISIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEW2</accession>
    <name>A0A6A6PEW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="3">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TIF6</name>
        <name evidence="4" type="ORF">BDY21DRAFT_331133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
        <text evidence="3">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEW2"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2462340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="14063" checksum="6FC9B27A65F72AAC" modified="2020-06-17" version="1">MAVRAQFENSNEVGVFSTLTNSYAIVAVGASENFYSVFEAELQDVIPICHATVAGTRIVGRLTAGNRKGLLVPTSTTDQELQHLRNSLPDEVKIQRIEERLSALGNVICANDHVALIHPDLERETEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKV0</accession>
    <name>A0A6A6NKV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_174940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKV0"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="101"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="351" mass="38688" checksum="7194FB050104C7DC" modified="2020-06-17" version="1">MSLQSDINVDASRFAPSSITQKTKALNENILKALDGAPKWWEIGAHAYRRLRKEGGTAFPKPVVLDTAKTLQLPSRDAGRTIPLRVVRPKDGSAIKGVYAHIHGGGFVLGDEEAQDVPLQWMADATSLTVVSIGYRLAPENPYPAGPEGLLRCGRLSSEERQSGIWRGSYVHRRRGTGTRIVQFRTLVNNFQLAGAHLTTVSTLHLLESQPNFSLRGVILHYGTYEMASFFPSVHLFNRAHILDKPRIDQFLIAFLGEKSEAERRDPRISPFYADFSGLRLPPALFTCGTEDPLLDDTVFMSTKRAAAGAEAVVKIYPGAPHGFTMFEAASCEPTADALQIVEKFLVEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKZ6</accession>
    <name>A0A6A6NKZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_294781</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKZ6"/>
    <dbReference type="OrthoDB" id="5600212at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="634" mass="70289" checksum="67C539565E1A929D" modified="2020-06-17" version="1" fragment="single">MSPQGPDADDSFFNDLSRQPDRDDGSSASRSNSIDAALPAQNDAAAGATAAAGAVSTTDPAGGTPKLKRIACVLCRKRKLRCDGARPTCGTCKRLSHDCAYDEVRRKSGPKRGYVKQLEARLMSEQVENLLKNQDEHGPDGRESSNPSFSAPSVPQGMGRDVTNLGLGGNPDAIPQIVPPGGLSPEEQMLQGGSGSLEGTSVDGGFPFEMIGLGLQEPLPPADVIDELHHIYFEKVHSSVPMIHRRRYLAAMNLGPNMRPPVCLRYIIWCLAASVSDKYECFQDHFYQRARKYAQIDEMKGHGESTISIAHCQTWVLICSYEFKLMYFPRAWMSTGRAVRLAQMMQLHRLDGQGLDVKQCLPPPKDWTEKEERRRTFWMAYCQDRYASIGTGWPMTIEEKDIMTNLPAIDDAYDKSKPMQTASLEQTFSLSGPSHLSTLSPFGGIVLMATLFGRNLTHLHRPTPNDNDHDIDGEFWKRHRQLDNILMQTTLGLPDHLRLPAGMQDPNVVFMNMSIHTSAICLHQAAIFKADQNHLSPSIGSESKIRCITAAAEITNIMRTIYTQDVAAMNPFVVFCLYVAARVFIQYLRSQPKDQQITSSLQFLLSAMQALKRKNPLSDSFLAQLDVDLEGAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLJ4</accession>
    <name>A0A6A6NLJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLJ4"/>
    <dbReference type="OrthoDB" id="722566at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12014">
        <property type="entry name" value="Cyclin_D1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="150" mass="16418" checksum="E258473B90AD63BC" modified="2020-06-17" version="1">MQPDEPAPLPEGVAEAIAEGSWNHGGGEREDATGADSGGAEPPYQGRLEAVKLTGDPNVPRGEYTWIAPDIGRGGLIRTATEEPFNGARIVKCAGHIAARDFRDDKYIPSQLIMVSHNHLAQYWEEFGHISFLRRVDLDEVPRTRGSMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM56</accession>
    <name>A0A6A6NM56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_358265</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM56"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058758">
        <property type="entry name" value="UBA_RNF216"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF42">
        <property type="entry name" value="FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26112">
        <property type="entry name" value="UBA_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="346"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="760" mass="84512" checksum="6B90F48DB22033C4" modified="2020-06-17" version="1">MPSLLSSLVFPAGGPARQEGQSNEEDGKSDGSESRDRSPPVSTGAVPSTGQGTNEGYIPGKLSTAGMRVENTTAIVFDLESPAFKTPHEEEEPGLKDLNAALEVLVEIFPDVRPDVFREMLREFGEESRLQLVTEAILRHGQKYVKGRFRAGLLRDTEEVGGSVGTGQKTTAGDSCKGSQRKLRSMNRHVEEVREKEEEVLLAAEDMFRSPAYKYAVKATLYAEFRGLSHATIKAVMAENNFSYTLSRPTLLQLVSKSWTYSITAFFTRRKLPSADSHPLITWSPSALDPSVLVPRLKLTASAQLNRELYDIFIAPTLMTQRGEQEALDWKIALQLNEQEAEEAGASFECGCCFGSYPFESVVVCDGGNLGVTNSTDGEGGDDRTAGLDGSPPHFLCFDCVRNAMQAALYGQGWSNAVDLSRGTLRCFTSTTDSCNGCIPASQVRQALLQTAPTTNRKDEKAAQQTWEKFEERLAADQLRRSSLPAVYCPFCGYAEIEELSDSARLMPLLQHTRIRPVAAAVVASVFTLLVVALMLYPLFRFIARYPIMVVFFSVTANYLFPYPPVPLHDVLRTSILRQMRCARGYKFSCLRPTCRKSSCLRCGARWRDMHRCFASSLEALRRAVENAAADAVKRTCPACGTSFVKSSGCNKLTCPCGYTMCYVCRAHVGTREGYTHFCQHFRERPGPCHQCGKCDLYKGEDEEVVVKRAKERAEREWKEREGGEGGRVVLERRRREGWWGSVGEEWLDWFVGLLVEVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMC9</accession>
    <name>A0A6A6NMC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_425020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMC9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="17724" checksum="394CE831019050CE" modified="2020-06-17" version="1">MDGQAGWRRWEVDGGCESESSSSASAPRLPSGRASWTPCEACPVVGSSSGVWFVLGWPWGAAAAAERAISSGGGGGIEANGERAAVCSVAEQKKPRPCYGVRRTALRSPTTCWVVRASVAAPDVARDCRRCTAAPTRSYLSTAQTHNGKERYATALSCERIFEQKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMD7</accession>
    <name>A0A6A6NMD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_404557</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with creB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat creC family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMD7"/>
    <dbReference type="OrthoDB" id="3367at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045013">
        <property type="term" value="P:carbon catabolite repression of transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051362">
        <property type="entry name" value="WD_repeat_creC_regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107:SF16">
        <property type="entry name" value="AT02583P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="436"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="166"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="565"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="640"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="659" mass="70457" checksum="4D1AB6CA7A5BA842" modified="2020-06-17" version="1">MFVLPPPPRYPTGAFNAGPGAPVIETNNTLSHPSGPDYQLVVGEGTYVLRDDLHLATPPPHPSEAPVHNPNPLATALSPPTAGTKLSLVKLAPSTAPVQKLFRTHSASRTTALPPFPGTAAAATATILDGSEAQSFASDSDSHLKSNGVSPALALLPSGVGSTPTFGEGNPALASAANARDSKDHQQLKRRKPKSNIIKSNSSFVSRVIPHEALQKRLQEHNPNGVFVFANINRAMQWLDFTSPSKDEHLTKILFTKAHALCHDVNPVTKSSSHIDLVMGFSTGDLIWYEPMSQKYARINKNGIINSTAVVEVRWLPNSENLFLAAHTDGSLIVYDKEKEDAPFVPEEGPAATAANGVAAADDSHGNALESRKRLQIKKSVQSRNQKTNPVSYWKTSNSRINGLAFSPDGRHLAVVSEDGSLRIIDFVGERLRDLFASYYGGLMSACWSPDGAYVVTGGQDDLVSIWSLDDAALVARCPGHNSWVTAVAFDPWRCDERNYRFGSVGEDCRLLLWDFSVGMLIRPRAASVRQRGSVSSHLPGVRNRVEPASAAAAAARLRSDSTLAAGASGGSASADADADADAEPDESEVVHEVEPRARVAMLPPVMEKSVDSHPLCWIGFEEDCIITACNEGHIRTWDRPKEGAAGSDGAPSMTGSCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMM7</accession>
    <name>A0A6A6NMM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMM7"/>
    <dbReference type="OrthoDB" id="3024632at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="11629" checksum="1ED5E2E7AC929FF7" modified="2020-06-17" version="1">MSSSFLFEFGSSLVEITAMTALIETATAESLISSGRSAAGIPCAAMSSFGSIFMIRACISTSTLAWMRSTIGMQSARVDAAVWLIENLDRTERGVWVGCGSDSHHARCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN03</accession>
    <name>A0A6A6NN03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cullin family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_356593</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN03"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000031">
        <property type="entry name" value="Ubiquitin ligase subunit CulD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="585"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="970" mass="108901" checksum="E08B5CD78E08AC51" modified="2020-06-17" version="1">MADPRRPASGTSGDNSSSMSPHPTSSSPDKKRKLATQHQHAHEQRYSGEHRLLDSDQHDRVASDASGKQPAIADCFPGPSKKAATAASSGDAAYDLDTSEPIAKKTKLTHLGSGTAGTASSTSELGDNAAAAAPQHPSSATPPHTSTSPKKMYNFPSPNTSPARSNGPSPVVSLTTSPHAGQMTAPGPTASKSPKRPIFDPYKGAKRLPVKGTSHKGPPINYLEITWPKIARGLDEVFADSNGWVHPGTSVEELYKCVTYCCKQKQAQELFERVEKVFRAHIDEKVRDPLFQMAKEGVDDLELLRALLTSWTEFNNQLVTTRKMFVYLDRAYLLQWQLPWTSEMGLKLFRDVAASENLRHKVFEGAYGLIVADRQGRGLDEDTFMQAVDMYHGLEIYTECFENLFLARSAADFESWTENSIMQKTLAAHVKACNELIANERNRCERFGLDASTQRSLMDVIRRVLVEERKISLVNHKDLNHLFDTNDVDSLELLYRLLERAHFGSDMKIAFEQWIKSTGTNIVFDEGHQDRMVVKLLTLKKRLDTFWRVSFHRNEELGGVLRKAVHAFMNTSKKTDATWGTDNSKPGEMIAKYVDALLRGGAKAIPQELSTSGVGRAPEADGDDGQDDVEFDEDAEVNHQLDQVLDLFRFIEGKAVFEAFYKKDLARRLLMGRSASADAERSMLTRLRTECGAGFTQNLEQMFKDIELAREEMAAYKVLAEARQQNSSIDLSVNILSAAAWPTYPDVTMVIPIEISKEITKFEDYYRSKHSNRKLQWKHALAHCQIRARFPKGMKELVVSSFQAIVLLLFNEVETGESLSYEFIKRETGLPEAEVVRTLQSLACAMLRPLAKKPKGRDINPGDQFAVNPSFTTDKYRVKINQVQLKETKEENKETHERVAADRNFETQAAIVRIMKSRKKIGHQELIAEVIKATKSRGVLNVADIKKNIERLVDKDYMERDDDNQYSYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN10</accession>
    <name>A0A6A6NN10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_156794</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN10"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2452633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="222" mass="24684" checksum="5630A43582F555B1" modified="2020-06-17" version="1">MASAIPAAGSRSSRPPQSSAARAHLLGYNFLSAILWASVLGRVVLLASLVGWQHVFAGTGEFAKWTQTMALMEVVHSVFGLVRASIMTTLIQVASRILLVWPVFTLFPGVVASSPACSTMLVSWSITEVIRYSYFVFVLGRGSVPEWLEWLRYNTFFVLYPMGISSECWLLFKSADQAAKMNSSLVYGLYAILAIYVPGSYILYTHMMVQRKKIMRAKRHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN76</accession>
    <name>A0A6A6NN76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN76"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="10640" checksum="16942DC28E823055" modified="2020-06-17" version="1">MGLGTYVPMYVCTGALFFLRFSFGCFGSIKWRQGPKPQTGWICRLGGMSVFAHRDCRIAGLSWGVYGAPESLRNAIRSYGRGLSWCLGSGATGGIAVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP54</accession>
    <name>A0A6A6NP54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiamine-triphosphatase</fullName>
            <ecNumber evidence="6">3.6.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_355958</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolase highly specific for thiamine triphosphate (ThTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>thiamine triphosphate + H2O = thiamine diphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11744"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:58938"/>
            <dbReference type="EC" id="3.6.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ThTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.28" evidence="6"/>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP54"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050333">
        <property type="term" value="F:thiamine triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042357">
        <property type="term" value="P:thiamine diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07758">
        <property type="entry name" value="ThTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039582">
        <property type="entry name" value="THTPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012177">
        <property type="entry name" value="ThTPase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14586">
        <property type="entry name" value="THIAMINE-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14586:SF1">
        <property type="entry name" value="THIAMINE-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="14">
        <location>
            <begin position="12"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2453458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="24629" checksum="0CAD3A277F2C62EB" modified="2020-06-17" version="1">MASRQGSKLSRVLEVERKFRSLAVRDLSQHGRFPHFRSLRKLPVQCLHDTYYDQSSLLSSAGAWVRRRNGAWQAKIKKGGTFNNSKFEELCDARDISSHITRITGTNKLEADNFGLLPIANFSTRRETWIADDEFHIALDIMDFGHEVGEVELQRVLHDIAGGGDLSEQQEQRLMQEMDEKISTFMKQYSWAFSPGEPKGKLTAYFERMRMKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP64</accession>
    <name>A0A6A6NP64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_121053</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAND family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6260732at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010265">
        <property type="term" value="P:SCF complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039852">
        <property type="entry name" value="CAND1/CAND2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013932">
        <property type="entry name" value="TATA-bd_TIP120"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12696">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08623">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25782">
        <property type="entry name" value="TPR_CAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="TATA-binding protein interacting (TIP20)" evidence="5">
        <location>
            <begin position="1185"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="498"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1404" mass="148396" checksum="8ADB9B8406BA8EB8" modified="2020-06-17" version="1">MAHAASTPQTITALLPKLHDADADFRYMALADLHQTLLATGPSQSQVHIVTNDSTLYTRLSDGLLHTLADSNGEVQNMAVKCLGPFATKVPAYVLSSMIDRIAGMGTKGGGGGGTTGQAVDESIPALALRAIVVALPKPVQGTPPTKATQDAYAAISCALIPRLVGGKAPSSASAGKSSGADKSGTGGSTTMGMLPADVAHGTDSNAIDVLTETARCFGPLLHRSEVDALQRSTLEVLESARTSSVLKKKAVVAMAALAPYFSQDLLSRFVSTIVERLRQPHLTSAKRKVYLTLLGSVARAVPRRFGPYLKVVGEFVLAAVSQAELDEELEAREEDDDGERNTEVDDVHEAALVAIEGFLLFCKDDMKSFLGESLDAALRFLKYNPNFTGDDEDGDETMGVDDEDNGLEGLEGDDFEEEQGFDDDEDSSWKVRRCAAKVLSAIVTTRSDEDLLEDATLYERVAPILISRFKEREESVRLEVLSTLSLLIRRTSEMHIVSSSASTTGQTDASMMPPPPAPSRKRRRGASDASMFDAQAAVIAASGTGFASPVNGGTPITGPRAALAKLSSLMVTGVAGLLRSSPSPTKQASLVLLRDVVVTQRGGLDEYLEQIMGPIADAIKASEAQTSGSSLANANGLRVCAMQLLGVIAETHSSKNVQPFMGSIVPALVSAIKDRMSKVSIEALAATEQVIKALTPPRALASGDANKDSLAQLYSVIMDRIRTSYVDIEVREKAIAVLGLLLGRTAASPGLVTPDQRKEGLDLLADRLRNEVTRLAAVRAIDVVIALADDKSQFEPAWVRAVALELGAQTRKANRGLRSAAVAALKTLAVNKATRDNLDAESIGEVVGMLPPILESADFYLVSQALVILSTFVRADAAAVVDAALVKRVADIVASPLSGPVVSSLLGLVEAIGEMGQGGPLMNSLLRGVGVNGNPDLVGKTVGTLLVAGASSVGVSLDDFVKELKGAADDVRRCLALAVLGEAALRLGKRSPLEPGFFMGYFDAKGSDKVALAAAVALGRAAAGDPERFVPEVVGKLERPRTAFERYLALNSVKEMLTHADGEEAGAGVVTFGKDLWKVVMEASQEGEDNRAIGAECVGRLAVLEPGVYLPELEGLLKDPSPGVRGLVISALRFTFADTDEAYDDHLRADVVGMLTAMLNDNELENRRMALSTVNAALRNKPHLVVPALGGLAPLVLGETEVRPELVREVAMGPFKIKVDDGLELRKSAYETLNALLDAAFPRLSLLPVFDRILAGVADDHNIRTLCLHMLTRLSTLAPDATRSVLNTLSGLFRTVLQTKPKENAVKQEVERVKDSANQVLRTTLVLQMAFGVADQAGPAGVGGGAGVPVGAMGASSLGAMGTAGGAAEADGIRDWVAYWEWCRREMEQGLRSAERELKEKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPI4</accession>
    <name>A0A6A6NPI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_292776</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPI4"/>
    <dbReference type="OrthoDB" id="165352at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="602" mass="68865" checksum="CDAD4A3DA2D63FA8" modified="2020-06-17" version="1">MPPGPQPPPTIRTPQDPSSGDVEKQEQGSSTGRPRGVSIQSPTSPTSGRGADRLSLDTLRRRPTRSNTVKKWVEPERTNWEEPGAEPGVDTRKDAEPHLHELHRECQINIVDISEEQIRNTELENATLEPFLREKKPGWSDCRWINVNGLSWDVIKALGNDQKLHQLAVEDLMNTQSRTKVDWYPGQAFILMTLQKLVKMRTRKGSDSDSESDSDEDLATLEKPRHMIKRKKKPLMVKLMNKFRSTYYWERRQRSKTFSGENAMDRDPKRFQRSFTMGNFGDFTTDTIRTLQRYRGGPNIERTEYMERNSALSDRNLAVTVEQVSIFLKDDNTVISFFEHSALDVFQPILKRLQSHDTIVRRTCDASVLVQALIDTIIDLAFAAVGAYEDTIGDLELDVLTDPSLEHSKQLYILATELALLRSTIQPIVGIVNALRDHKGEPIGMGYMARHSSMAVGSITISPLAHTYLGDVEDHCLMITQSLDRMMRAADNMIDLIFNMMGSYQNESMKQLTAATIFFLPLTFLTGYFGQNFSRFDAVDLHSDVFFWYIAIPVMVLTVLILWNEMIVRVISRFFQRREISRSRKARSQSNERGKKGQKKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPM0</accession>
    <name>A0A6A6NPM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF500 and domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_117935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3YL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPM0"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11842">
        <property type="entry name" value="SH3_Ysc84p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11525">
        <property type="entry name" value="SYLF_SH3YL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033643">
        <property type="entry name" value="SYLF_SH3YL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="370"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="257"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="309"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="429" mass="45561" checksum="9D82436C07C4DF44" modified="2020-06-17" version="1">MPLGINNPLPASMRSECRKAGKILASFVDPRQAFGPDKVIPPQILANAKGLAIITVFKAGFLGSARFGSGVVVARLADGSWSAPSAIGTVGGGFGGQIGFELTDFVFILNDRAAVRTFAQAGSLTLGGNVSIAAGPVGRNAEAAGAASLKSVAGIFAYSKTKGLFAGVSLEGSALIERRDANAKLYNNRYTARQLLEGSVPVPPAAEPLMRVLNSRVFSGIAGQGTMPEQMYNDIPVYDDRHEDVVWQGRTGSAYGEGVRSDRTGSFGGGGGGANDYEYHDYPRPGGGGGAPSRASTWQDDLYDRGPPAQQTGGLNRSFTTRANPTETFDRMERRRTGGFDDNYAYGDRSKPGRPTAPKPVFAAQKKNSMGPNQAIAKFTFEPDQPGDLGFKKGEVITIVKRTDNETDWWTGRIGDREGIFPSNYVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPR0</accession>
    <name>A0A6A6NPR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Electron transfer protein 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_292302</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2</text>
            <dbReference type="Rhea" id="RHEA:63388"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:61715"/>
            <dbReference type="EC" id="1.17.99.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:63389"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPR0"/>
    <dbReference type="OrthoDB" id="1726137at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120547">
        <property type="term" value="F:heme A synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01665">
        <property type="entry name" value="HemeA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023754">
        <property type="entry name" value="HemeA_Synthase_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="55083" checksum="C5E9DDED4BE01C1D" modified="2020-06-17" version="1">MMASVFRALPVLRRAAPNLSRELFTCRTCSTKATASLRSKALLMSNIPRNYGIRWNSTQAIPSQAVSQHGAKLVASKTGTENGAKEGGRATSRVYPQTSDKLVAYWLLGSAASVFGIVVFGGLTRLTESGLSITEWRPVTGSLPPMSAEKWESEFTKYRASPEFHLLNPNMTLEEFKKIYWMEWTHRVWGRAIGITFLLPTAYFILRRRVAPHMAWKLVGICGLIGFQGVIGWWMVKSGLKDELFAPGSHPRVSQIRLTVHLGAAFAVYAAMLRSGLSILREHGARAASPEEADKLVRKLLHPRMRVFRGLVGALTLLIFATAMSGALVAGLDAGLIYNEFPYMGVGLAPPKSELFDPRYSRIEGQSDLVWRNVLENPSLVQLDHRALATTTFSAIMALWCYARFGRSMRAVLPHNACKGVTGLVHLAWVQVTLGISTLLYLVPTWLAAAHQAGSLALLTGALVLSSRVGGSARVLSLLRQRARLAAKHNGKSVADVLGPKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPX9</accession>
    <name>A0A6A6NPX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDP-mannose transporter</fullName>
            <shortName evidence="7">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_354924</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasmic vesicle membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPX9"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="539" mass="57659" checksum="826CF6457CC54099" modified="2020-06-17" version="1">MSARPGSRASSSASTGSQSGDAGPGSQLHPQNIPLIDLSSRSPSPYARSRPAAATAASEDDDDDDYFLFEREPSVVRPLVADDVGTGAFSAGGGRRLAGEGSRSSWRRVLRAGGLGSFFFGTWIGWQVYVALLVVWVGGCGFGLLLMNRFILLTGVYKFPYPIAATFIQLVIAHLCLIGFSAFTRAMAQPLSRLGLGAIVAPSVPSGTQGFRGTPKSYPFPLSLLRKIPGGQGGIAGGGIFEFDLKVARQVLPLAVVFVGKVLLSNLSFAYSQMSTYTLSRVGIVPLALIFTAFLTRASHSTGVLSSTLIATITLALACIRTDARVTWESTVSGVFSTLFVALYPILLLRTYRQLVSDLVPQGDALNLNTPHNTLFVDGTTTFPMTSTTSSDAAAVDGFASGPTSREETRAYYRILHYTSLLSLVLLAPVLLLSGEVSNIRHNCYFLDVPFFWFLTVCGGLGAWAVFTSAPLLAKAAGPLALAFVGTPRAAFQLVVLGHFRLPGYAWVAVAMCWVSAAWYVLVRRDEGRVGERRRLEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ35</accession>
    <name>A0A6A6NQ35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_122868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ35"/>
    <dbReference type="OrthoDB" id="2238745at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF174">
        <property type="entry name" value="ARRESTIN-RELATED TRAFFICKING ADAPTER 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="299"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="692" mass="75708" checksum="83D6B0CE810F0C87" modified="2020-06-17" version="1">MRTTARDSVGGPVSGLVSRPSLAESVRSASDRPPTSPTASSILKAMPEEKPVAIANGVSVSIHLAEPVLFLQGFEQGDTHSRSTAMLRGNLHLRVSKGAKIKAVTLKFRGRAVTKWPEGIPPKKSEYEEVNNIMNHTWPFFNAQFPTAETGTGADHVSLRNHHSSLQGLKSRVSSESSPTSSSFNLSPKDARKLSLQVNQSRSFGKGESATGGPTVAQKGYRTFSPGDYIYNFELPIDSHLPETIDVDLGNVKYELEAVVERAGAFRANLIGSKEVVLIRAPSEGSLEQVEPIAISRNWEDQLHYDIVISGKSFPLGSQVPIAFKLTPLAKVQCHRIKVFVTENIEYFCSNKRVHRMEPVRKVQLFEKRADAAPVSTYPGSTVRVISGGGVPYDQRAQAARGEDFSPQDPSNLLGSLDGEAAIGPTEMEFNVQLPSCGNMREKERGFRLHFDTTYQNIQVHHWIKIVMRLSKPDPNDSSKRRHFEISIDSPFHILSCRATQANTELPAYSSPAPEEGSQRLFECGCPGAMPMRRTTPPSFIPTPPEGNRNGTRNPNNRHSIAVTHGGSGLARPQAAHLSGPMQRPIHILRMPSFNPPEFADDDPPPPMETPPPRYDTIASPTSGLADYFSRLSDAYDDESEGSGDSGEGEADLSVGVRARLARSRSRVDVPLTPGSRVNRSMDEPRTWGVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQR5</accession>
    <name>A0A6A6NQR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_400446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQR5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="31677" checksum="754BB5348BC8358D" modified="2020-06-17" version="1" fragment="single">LRIRPRPRSLAPRRPALHPPPVHPAGLRHRLTHRPRHARVPAPRPPRRLRRPQLPRLVPAHRQRARARRPAAARRRPPPRRQRAAQRARLARRRRARRRRRPRQPRQLAQLRARVRRRRMRVDGVEQRRQRLGRGELGGVRGGGALGGQLGEERREARAAGGGGGGGVVVGAGVGVGGAARGGGSGDAGGGSVEVDGGPVVGEGGGGGWEDVGSWGDREAVEVGHFFFLDAPKGLDVCERGESVEPWLLGGSLRAVGSASRGAPRCGSHLALLKCWWDRKLQVAVGRRHHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQT9</accession>
    <name>A0A6A6NQT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_387833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQT9"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="28655" checksum="117A51805226C9A0" modified="2020-06-17" version="1">MSTTLPILPGRAIQSPAKRAHKTDDSTFIKYRTRHEVQREVDAIFFVRRNTSIPVPFVIQSHVQESGSWLSMYSIPGLPLTNIWTRMSEEAQATTQQDLSIHISELMAIRPPEPTYIGSCVGGPAYDHRLNNGLPYRPFASVSDFHKGLVAPVTRFPRPQLAVEYRQQLADDHDITFTHADLCGGHILVEPSAGKITGIIDGEMAGWWPEYWEYTKSLFGSRYVPWRKELVEKVLHPYPSQLRIERILQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP6</accession>
    <name>A0A6A6NRP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sacsin/Nov domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_416707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10031156at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022155">
        <property type="entry name" value="DUF3684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12449">
        <property type="entry name" value="DUF3684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="2">
        <location>
            <begin position="30"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1436"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1738" mass="193435" checksum="59E50690A11D9B58" modified="2020-06-17" version="1">MAGDVDYARMREQTLRVGADEVVTANIRALVDKILARYSSEFTTLRELVQNAADASASKVTIKFDTLPSHAVPLPSTTDRSALFRHVLQHHTVRRLVVTNDGQPFSGEDWARLKRIAEGNPDETKIGAFGVGFYSVFNDCENPFVVSGGNSMAFFWKDNALFTKYMSGSDQSSKDTSFILDYRDTTSPLPDLTSLCKFLATSLTFVALEQLELFVDDVNVITLKKKMAPSLPVPIPSRLKTQSKGRLMQITGVDQHSAQIDAQWINAIVWNRQSDSPDSQGTYAGTPKPQNKAGGSNVGFKSFFTRLTKSIDPQANAKAAAAEKEAAAQKAAVEDLCGVSGGTVFLRVSTVAIKTNVGGIASELERATKKAPPKQTEISLLTTPHDETTAALSTTSGLTGAKMADIFASVIPTAGGRIFIGFPTSQTTGLHCHVSAPALIPTVERENVDLSARHVSTWNIDMLRIAGAACRILYASEMAEIKGALSKAVSDSAKTPRRDEVAKVAPNAVNVLQRYTWTESTPSPHIGSIIGEGFWDCSRDIDILSTRGVLRCADVRVTEEDMSFIETTPLIPKTILTSNEMFIATLFNRGFLQELGISDIKLELERHPLSESQGIEFLRWLAGKVDGQHFDRGIAKRLLDSTVISMSTDEGSAESQQPNETSRSLAKRLAPSVLDLRDVNSYADAAKISASMPLPPYTIPTSLSVRLTHKELQSFGWVQLSLVTWLMFLVNHGECERELTTSAPFASHVLQHLSKGWEQLPPDMKTTVIETLSHRAVIPTKQGLRKPGESYFSSVKLFKDLPQVQVQGVKERFLVCLGVRKTIELSVIFNLLDAPDDGDGVATRWSHVDLIKYLASIQDDMPEADIKRLRTKAFCPAELAKEVEPSHLYQVSDLCFPEQQNKNLGLPVLKWPEYLSPSSGEAKLLFRLGLKRHAFASDLFDIMGKTAGNDWQRYNLALNVFFNNVSLHYYLSFDRRTVQNLKFLPVEGSPEIVSPSECFTNEKAARLGFRILRADLHNRADMFGVRRDPDIETCAATFLSKPHEFLSSRPKARLLFEYFADRSDEIGTSLAARLGESAIVPYKDRRKGDETTSFIQPRLCYIGSSHKYDRLVPFVDFGTAANLFLLKVGAKHQPTTEELAQNTVRSPADTLNMLQQEGYLELLRSFAAANAKLKENKALWQQMKKVPFLLGYRDVVAHNSTSKDPEKQMMSSTVEVADVDSDDEEELAREWSLQKASDIVIVDQVEHFRRFKDSLHAAPEDERLEAFYTSLGTPFIGSLVDVRLNTGTKTPDRGHATQLRARIIERSRLFFHECSHDQILRDHKWLDRHLKVEFRSAIQMVVSLKTRRLSYSRKTTAALEGTRRECLCVTADFDQFEVARQLVQLLLKRPQQRDALAFEKIMFTRLTRLRDMGYNVERIIRRREYESRIANEQMAQEERRRLEAAAKTPPRPPLQPKQPSIPGAFEQDDSPSKPKDDLSEAFNELNLVNDGKKLFDRLKGHLGWNQSQDSLGPLKGLLGDGADTGKPQGVGESNPAVTRDRINRALKGMRAYNGEAHNSRDFSQTVDEVKASYCDRKPGHSLERAGAVGDMPLFISRDVPEPERGAYVRDEMPGMRIFGAALEHVAASYGFAPGKLHVFADARSSSIAFNADGAVFVNYEAFKKADLGRFARAPDGSFVASADAMIPPMIAWWSTVAHELAHNLYSNHDANHTHYMGAIMEEFFVPMAERIALVKRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRZ0</accession>
    <name>A0A6A6NRZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cercosporin toxin biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_353327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRZ0"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="332"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="422" mass="45971" checksum="A097E4BFABEBC9DE" modified="2020-06-17" version="1">MGPLSHPILIIGTGISGLALAQSLKKHHLPVRVFEKDSPQKPRLQGYRIRINGDGQRPLQACLPAPLWDLFLTTCHAATPSVLNYDALSGAEVGRMTGPPPGRPAHDVVPRVADRRVLRDVLLRGLSEEAGEVSYGRRFARYEVDEAAGVVRAFFADGSVEEGCLLVGADGVASAVRAQLAPGHVMIDTDARCVYGKTVLTPALSEAGFPREAAEMMAVAQDGSKGGDSPIMLFMDPVRFCREARETQDAVKIPEDYVYWVFGARTSLFGLSDEELHKMSNEECVKHTVELAKEWHPSMRALLELQDEEQASAIRISAAKPPLKAWEVSKWVTLIGDAVHAMPPTGGSGANTALRDAAGLSEVIVRDVEEGRVGDGRTDGWSLGMYEAKMREYGNEMIEMSFRGGKRLIGMPPTEECKRIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSP7</accession>
    <name>A0A6A6NSP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_105879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSP7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="21538" checksum="7E094076C083B5ED" modified="2020-06-17" version="1">MTRPTPPRPARGSKGPRPHARPRRGDEDRTELGYRPQPAVVANSTRVASRTIRAAAASTTLTLRARNRCAPGRSAREGPARKGACQAWSVPAAACKLASRSTIFAGVDSLSCALFLSASGCGTSLVVRSCIRKKKVDHPSAWVRSRASIPSKLRLGPAATRLQAFLAVTPLYVSTRSVVVTAKSHRQRKEKPDGLASCCKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSS9</accession>
    <name>A0A6A6NSS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSS9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="381" mass="38193" checksum="33F90A117F64F94E" modified="2020-06-17" version="1">MGQFNPASTASRTATPSPREAHSPPSIEGLLQETNLDGPSRPWLSSRMATASGPSPTTTTTAVTPVSTSRPSSSSPPTFARAHASSLATLRALPPTSTLVLFSPVLPLPPTLLPSNPTTISTPTPAKPPRRDTDPSSSRPTSSPPTPTPAGAGQDDRDADVDDEPPMDPFEPLGRALSRHHRRVRHVPFVPRVGLTATHGPFVALAGAVIVVVVVATISPASPASAPASARAGAGGASVQGRPRRGGAGGAGFMDSSGAAGGKGIAGSGTAAEQLAFARRVVELVAGRDAAPPPKVLVVVSDLGAAAPGAAGAGGGEGDGDGGEKADREEDEEVGEDDLLLLFGPEGAREVEGFETVVRCGGCGREGLEEVAGKVFGVGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NST3</accession>
    <name>A0A6A6NST3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_308153</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NST3"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="11755" checksum="6B6513D4A704217C" modified="2020-06-17" version="1" fragment="single">MAKNAGKMQNLINYRMKATLNDGRQMAGQMMAFDRHMNLVFADTEEFRFVRRRNKTTGATTLTEEKRNLGLTIIRGAFVVAIQVDGPPPADPSARLGAAAPSGSGAAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTF6</accession>
    <name>A0A6A6NTF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTF6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025652475" evidence="1">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="7811" checksum="6B2B41CC7C7E753E" modified="2020-06-17" version="1">MQLTTVLASTLALFASSASATYYGMNSTMTTSAYMTGTSAPSPTFSQGAPFTGAAAPHATAGGVAGPALGLAVFGGAALFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTN4</accession>
    <name>A0A6A6NTN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTN4"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="7844" checksum="F6FBDF0E3A31DC9A" modified="2020-06-17" version="1" fragment="single">IKFKDAVGRKFSFPWDLCKTWHGMEKLIQQAFAHVDVIGPHVMEGHYDLVGPDNEIILPPVWETMVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTV1</accession>
    <name>A0A6A6NTV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_290437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTV1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="347"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="363"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="394" mass="43866" checksum="2FA328EC4EEA5A96" modified="2020-06-17" version="1">MSGLPERAQQVIACAASTVIISGIMVVLRFFTRTAILHSLGWEDWLILVSLVGSLQRSKYLMCTLASYQRDMTLPAYRTNSMQAMYATILLYGMSLTFAKLSILLQYLRIFSVMYVRKVCYIQLGIVTAYGAWLFFCSLLSCVPIEKNWDDSVDGGCIPTTEMWFANAGINIVTDFMIVLVPMWPVRKLKLPKRQKIILAVVFAVGFLACIVSILRLYSLYLATISDDSTYDNIGVAIWSCLEINAAILCASVPTIKPLVSRLFPRLLSNSSRSRTMYNTRANGGQTGNTNLSGNRLRGASQNPRRVGADTESNKGIMSAEVFSLEQMKNDDLELERKYDNHHFHAHVQGADPNSSGSLSDTSEGHDGSGWRDVEHGGIRVERTVKQTVDHHVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUE8</accession>
    <name>A0A6A6NUE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_365602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUE8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="33007" checksum="2E59F86F4C2DCABE" modified="2020-06-17" version="1">MSKNQEIQSFPEAEYSALRKAIYVTWNYISLFPEFGPATKVSLAENYNKNCRVLDGKYHKKVDVTAIEYCLEGSEDAPYGYKRFQNTAKGWTTVLRHDFMDLLLSAGYDKREIMFFSTKEAIADAIRAVQRIFQYLDGSDKITGSAIKCRARILAGMDVWEFSSREREETNHQVSRFLSGPPQVDWSHPTGFERRIVGFWKEALLESGRGNSFYKTTDREAVREAIENMYVHIHTWDCVLQEEFGLFGHYPAEKVKRRIECYALTYGFIGGPEPESRWKSIYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUW3</accession>
    <name>A0A6A6NUW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor eIF 4e-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_68149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUW3"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="372" mass="40137" checksum="1920293F1E87F830" modified="2020-06-17" version="1">MDRENLWTRRSNSSKLSLSMNNSNDSHDGGSTTRPDPPSRTFSASKRFGGGDTPSGSARPNPFNAMSPLTTTNISSPTSSASNAFGLGSGAFASFGSAAKTPKTPGTAFDFSKAAMSGQAPSTPGAEKRDNKGSLSRMTSRSAAPPGIPEVSSTTPAAPVALDKPTGAKEQSGKPGGGRDGGNIDPAVPWPLKYAWVIWYRPPTSKNSDYEKSIQPMCRMASAQDFWSVYVHLKRPSSLPTVSDYHFFKEGIRPVWEDEENRRGGKWIMRLKKGVADRYWEDLLLAMIGDQFLEAGEEVCGAVLSVRSGEDVFSIWTKNDGGRNIKIRYVCSVAAQCQPTPCIIPLPFFPPSKSLVNSSPQRNHKARPLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV19</accession>
    <name>A0A6A6NV19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_289151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV19"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070139">
        <property type="term" value="F:SUMO-specific endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051947">
        <property type="entry name" value="Sentrin-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896:SF3">
        <property type="entry name" value="FI06413P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="72"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="271" mass="29956" checksum="99C88B45CCA869CB" modified="2020-06-17" version="1" fragment="single">MKNPDNSDSKAASPTSTTVERSLRSSKRPNNAGTSTSEAEPHKEKEPVIAGMDVGPQWENEVYYPRTGPNRAIVGWQDVGCLNVGEELNDNIINFGLRWISEHTTIKDKVHYFNTHFYSTLTTPGTRGINYNGIRNWTKKVDIFDKDYVVVPVHADNHWFLVVICGLPNLARTPTEEGEAGSSDFGENEREPRSSGSRMRAPDNGATIIVMDSLGITHPSTIAALRSYIKEEGRAKRSLEIAAGDLRGTHGKVPHQQNDSDCGVYLLGYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV96</accession>
    <name>A0A6A6NV96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_351471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV96"/>
    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048205">
        <property type="term" value="P:COPI coating of Golgi vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000013">
        <property type="entry name" value="Putative Arf GTPase-activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="10"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="137"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="214"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="526" mass="54419" checksum="7D8DCB8996E7A2CB" modified="2020-06-17" version="1">MALATKTQSQKIFEKLKTKPANKICFDCGAKNPTWSSVPFAIYLCLDCSAHHRNLGVHISFVRSTNLDIWQWDQLRLMKVGGNESATRFFQRNGGSAALASKDLQTKYTSNAATKYKEELARRVAADVKLYPDEVTITDIPDSTDSPAGASTPSGDGGDDDFFSSWDKPTIKRPSNPPSRTGTPGPGSSRTASPFLNAPGGSNGAPGRPKSPLSASATTNAEGAGSGTTATPTAVRPAAAIRKTSSQSAGGAGATARKTNILGGKKKGLGAKKVGGAGAGAGVDAALDFEEAERKAKEEAERIAKLGYDPDAEAAETSAATKSGAGVGAPAADSAPSSRVVSPGPGSPGRAGGFGATKGRERRSEDMERLGMGIGRLGFGQTGGAKPAQQPKKPMGFGSTSKAVEDDSDRYARDKFASQKSISSDEFFGRAQFDPGAQREAKQRLQGFEGATSISSNAYFGRPENEGGPGGAGGGGVDDYGDLETAAKDFVRRFGITAGDDLENLTNLLGEGATRLQGAIRSYLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVA7</accession>
    <name>A0A6A6NVA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-3' exoribonuclease 1</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_307126</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016494">
        <property type="entry name" value="5_3_exoribonuclease_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006743">
        <property type="entry name" value="Exonuclease_Xnr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="10">
        <location>
            <begin position="728"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="11">
        <location>
            <begin position="920"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="9">
        <location>
            <begin position="1161"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="447"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1291"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1387"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1420"/>
            <end position="1437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2455651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1446" mass="163012" checksum="9C24C6F36230D973" modified="2020-06-17" version="1">MGVPKFFRWMSERYPTISQLIAENRIPEFDCLYLDMNGIIHNCTHNDSDSPTHRMSEDKMFIAIFNYIEHLFGKIKPKQLFFMAIDGVAPRAKMNQQRARRFRTALDAEMAREKAIREGIEMPKEDPFDSNCITPGTEFMAKLTVQLKYFVNKKVSEDKDWQGVEVVLSGHEVPGEGEHKIMEYIRQTKSQPNYDPNMRHCLYGLDADLIMLGLLSHDPHFCLLREEVTFGRQSQKKSKELEHQNFYLLHLCVVREYLELEFQELEAPDALSFPFDMERVIDDFILMAFFVGNDFLPNLPHLHINEGALALMFNVYKTVLPKAKGYLNEGGVINLERLALLLDELSHVEYRFFESEVSDAAWFKGKQMGKEDVMEKTKRRGQLVITPKQREIFRGIKNYVNSRSLRSELQPYDLPASLPASDRKFVEELADNLHVKWKTVEDENGDRHLQLSFPPRVPMNGAENEEDDEEEKDDEEAQIAMLRVLKKYENAKVEEMTADDAQAEMQKKYEKKFHQWKDNYYKSKIGWGLDNEDEMRKMTENYVQGLQWVLYYYYRGVVSWPWFYGYHYSPMISDVKKGLNADMDFKLGQPFRPFQQLMGVLPDRSKQIVPQPYHDLMTNPESPIIDFYPRDFELDMNGKKMDWEAVVKIPFIEEKRLLAAMGTKEGLLSEDERNRNEFGVSLKFTYTSDLDYAYPSSLPGIFPDLEHCHCIENIFELPTMEGLEVYVGLVDGVQLGVAALAGFPSLKVLPFHGQLGFHGVSVFQQESRNESMVLTLVETEERSKISKARERLGKAIHVGYPFLQEAKVVKVSDELFDYTLATDGSGQVIQTPHNPHEIGAWKKKSDRVESVYSKRLGIIIGSVESLVHVAMLKGLRKTDDGATVKEYGEIPGMETDYATQTIVDDVVSEDARFIEREALPIEEEFPIDSKAFYLGEFNYGRPLQITGHIDQKAEVWVLTLKGREPEFGREIARNAERLTPYTPSFAVAKMLRLNPLVLSKLTSSFSVNSSGLKLNLGLNLKFEAKKQKVLGYSRRSATGWEFSPKAINLITEYMLKFPEFIAGISRNPKGDLYEDTNFYPEDIAKTKMKEIGAWLKSIESKSFERVPLEAEQLDSEVVKAIEQAANAALASGPEPEPRRIRGVPRAALLKPSDAESRLGGQKFALGDRVVYVQDSGRVPIGGRGTVVGMTRTARVTLLDVVFDTTFMSGTTLGDRCSPFRGSTVPATSVLNLTTKQVIAWSKASTAKQPQQQFQPLTVQNRVYGAPMATSGQPQLFPAAAPPPLRGSFRGAVTGHLPGPRGSPRSRGRGDAAIQNGHTRQTALPFHPANRGARGGNTVAPRGQHMNGQPLRARGGNTNCGPPLPGQRNHRGYVVVDQMDPNEGVGKRNSNFRPQSYAATPPPASLNAGRGGRVRGGRGGRGGDRGVRARGPNADRGRGSTGPTATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVD1</accession>
    <name>A0A6A6NVD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H/ACA ribonucleoprotein complex subunit NOP10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleolar protein family A member 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">snoRNP protein NOP10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_324350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NOP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVD1"/>
    <dbReference type="OrthoDB" id="13807at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904874">
        <property type="term" value="P:positive regulation of telomerase RNA localization to Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.40">
        <property type="entry name" value="H/ACA ribonucleoprotein complex, subunit Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="Nop10-like SnoRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="9529" checksum="D6D06C1947510C2D" modified="2020-06-17" version="1">MHLMYTTDLATGKRVYTLKKVVDGEATQSAHPARFSPDDQYSRHRVTLKRRYGLLPSQLQKQVTQDLQPKPVKEDEKNGENST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVT5</accession>
    <name>A0A6A6NVT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase M18 aminopeptidase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_416135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVT5"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF4">
        <property type="entry name" value="VACUOLAR AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="489" mass="51662" checksum="87FB89F5A8007347" modified="2020-06-17" version="1">MAATAPAKSKASSYTQPFCDFLTSNPTVFHAVSAFAAQLEAAGFSRLCERDPWCVRPGGRYYVTRNGSSLMAFAVGASYEAGNGAAILAGHVDALTARLKPVPKLPPRGGYAQLGVAPYAGALNTTWWDRDLGIGGRVLVRKESGKVETRLVKLGWPIARIPTLAPHFGAPAAGPFNKETQMVPIIGLEGEGQQSVEVNGREFTSSKLAPEGSFVNTQPEKLVKAIAGELGIEDYSSIVNWELELFDVQPATAGGIDKEFIFAGRIDDKLCSWAAMQALLNSVSDSAATSSSSSIIKAVGLFDDEEIGSLLRQGARGNFLPATLERIVDSVAASSSSSSGFSTPSLLTQTYANSFLVSSDVTHALNPNFMGAYLEQHSPALNTGLVVCADSNGHMTTDAVSTAILSACADRVGATLQIFQIRNDVRSGGTVGPMLSSKMGMRAIDAGMPQLSMHSIRATTGSLDPGLGVLAFQGFLDTYEEVDKEFREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVV9</accession>
    <name>A0A6A6NVV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_62609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVV9"/>
    <dbReference type="OrthoDB" id="4159136at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF5">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="18290" checksum="EC93573F92C68127" modified="2020-06-17" version="1">MAWGRGGAGNIEQAAGADKRRAEDVEAAQPSASASDDPLPSPSHAHPQEYAHMGRGGAGNFYSPATLTSTGTFTTTTASTPGAGTSSSQLAEHAAGHRGRGGQGNFVWRGEAEAARERAEAEARDRQDDLSERVARDVEAGLARPAKVHSEEGRERQKDGEGGGYGQEGAEWVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW65</accession>
    <name>A0A6A6NW65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_307220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW65"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF5">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASE PRCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="108"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="298" mass="33119" checksum="13ECDB162EF63D5E" modified="2020-06-17" version="1">MAGSGHSYDPNFTQNCIDAIGPKASPRTREVMGALLRHIHDFAREVELTTDEWLAGVRFVNSIGQISDNTRNEAHRVSDIIGLESLVDEIAHKHVNESGQTPTSSTILGPFWSPRAPFRNNGESIIESPHSGQVALMHGKVVDMVTGRPIPGAVVDIWQASSNGKYDFQDPENQVDNNLRGKFRSNEKGEYHFYCLKPTAYTLPTDGPAGVLFDLLDRSPWRPAHIHLMISHDDYSPVVTQLYPKGDPHLHDDSVFAVKPDLVVDFKPRQGDPKAELDLHYDIKLAPRDSKSASVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWT0</accession>
    <name>A0A6A6NWT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_306112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWT0"/>
    <dbReference type="OrthoDB" id="2129362at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43072">
        <property type="entry name" value="N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43072:SF23">
        <property type="entry name" value="UPF0039 PROTEIN C11D3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13420">
        <property type="entry name" value="Acetyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="22017" checksum="56E40E8607FA2BAA" modified="2020-06-17" version="1">MAAGESPPTVLRPCQESDIPALNAIYSHYVHNSVATFATEPTTDEDQLQTFRSVKRQALPFIVGVDTSASTAIVGHCYASGFRPDRAGYRHTVEVSIWCHPAHQGRGVGTALLRRMLAVLEQPGRWPEYACDARPEDSIVRQVVVCMSVDEEGKRGGLALKEFYERFGFEVVGRMKEVGHKFDRWIDTMYLQKSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWW2</accession>
    <name>A0A6A6NWW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_58577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWW2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="211" mass="22399" checksum="561BB3DA2E1658C8" modified="2020-06-17" version="1">MTSRGSEKTANSVLKLSAPSDRQFNKHGRQATSTQLTTPKPINKTPQCPHSRACATAGQVPPSSSSPGSSPSPSSRPQSRLSLSKKAAPEAVKPASHVYSMNNRRVLAIHALAPDAVRRPGSREMTGRGMPRRIAAQQPCSAAHGRNHHRRPSASTTHTTPQAASQLGPPFPRHPGSSAAPRRPPCRALPDLPPPRRTANSISSGLVANRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX23</accession>
    <name>A0A6A6NX23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_288240</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="898"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="938"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1019"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1123"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="277"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="608"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="902"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1216"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="835"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1478" mass="162472" checksum="BB7082FB8BB20A63" modified="2020-06-17" version="1">MSHPCPTDGSFGPTVGSCRGGFDFTLLFEESILGLLPQAAFLLLAPLRLVTLRRRRSRIAKGGHLGTLKFISSVLYAASSIVLLVLWSDVAQFRTRASIAAATVELLGSVMIGVLSRLEHTRAIRPSHLLQFFLLTMLACDAVHLRTLCLMDYPSSFIVSTSMHTTLAALMLLLESLGKTDLLSNSHAKSVPPEQAMGLFETRLFIWLNKLFQQGYRKVLTPQDLLSVDDSLLSGDVRSEFRQSWTRYPKKTGRYALLRVLLTVLRKEFLLPCIPRLLTTGTEIAQPFLIAAMISFIGRPDSEQTRNMGYGLIGAFALDYTLLAVFSSWHAQGVAKFNVKLRGCLISAIYHKALEIPSTDINLSAATVLMNVEVEKVVNGFKFVHDIWALAISSAVASYILYTYLGVSFLAPLLATLAAVLATLLISKNVKVRQAAWGTATGVRVSQFAQTAGNMKGIRMLGLVQVVQNTLADLRAKELVKYRYGQLLVWVLAICSLFQIATLFAYLVFAIIGLSTGQLTMKFEDLFASLSALKLVTTPMLFVLQHIQVVQNGVASAQAIQKYLQKESQPDALQENDASTLTFGHESDSIEMRPLRNDTGKEERQYAVQIKSANFGFEHGRPLLTSINLKLRTGALTIVIGQIASGKSMLLRSLAGETTLLQGAIDRPPGGMGFCSQTPWLRNLSLRENIIGESEFDERWYTTVTWACGLDVDFAELDRGDATLVGSRGVSLSGGQKNRLSLARALYSRRPVMLIDDVLSGLDNTTEKLVFERVFGRRGVLRKSGTTVILATHSTRVVSEADEIVVMANGSILEQGTYSGLRTKADFIREIKVQENEHSKAEGGDEDHESTNSPRSKHRACRDASGNDQNEEETDQTRRTGDIQSLLYFLRVVGRTTLTCYFILQSVSVILSTMQFIWLKMWAESTDGSRSSAVKNLAIFVVITIASIAATSLWIAQFVFAFLLRASSALHSNLLQSWMNAAYSFIASTDVGSITNRFSQDILLVDSQLPYSWSNTTDAIGLILANFGILIAATPPVAAIMPILGAIAWMIQRIYLRTSRQVRLMDIEAKAPLCTHFLETLEGLSTIRTFGWLDSYKRQNTELLNRSQVPYYLLFSIQNWLKLVLELMIAGVAIVVVGSATALRSSIDPGYLGLALVNIMDLGIEMRQLVTAWTDLETSLGAIVRIRRFVLTTPPEEDPGIPKAEPPASWPSSGSVEYRGVIARYSESGEDVLRGIDLRIRPGEKVGICGRTGSGKSSLVATLFGLLKVADGEVAIDGIPLSSIPLEVLRAKVTALPQDSVFLRGSVRYNLAPWISETSSSPTPLPSLHRSNVPDSKLVQALQGVGLWNRLAAAAGEDKDEAAVLDWEMKDVDSVLSHGERQLFCLARAIVMDGRIVVLDEATSSVDTQTEKRMQNILRSAFGDRTVLAIAHRLESILDFDRIVVMDTGRIVEVGEPETLMATQGSLFKTLVEAQRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX80</accession>
    <name>A0A6A6NX80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_56312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX80"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="272" mass="29694" checksum="4DE3AE0094BAAFCB" modified="2020-06-17" version="1">MQLPVRPASSQRCTIDALSFALFSLSLQLNAGVSGALSLLYSDWQAQKRGLQTRRAGAEGKSVAHNPWASSVSWAPVGTLGPHLANHFVVHFSPIATVLPVLGLASEWHCIAGYVFCLCLLSSSLTPREHQIVIYWFFAFSVMLNMDHESVAPRLNLHSCSAASGSEDLGQQIANHATPSLSSRTNTACRSRSLVFAIHNIARDKRRDERTHTISDLSETRGSLLAQRPNAPLPESSRMQGLIRVVGNIERSRIPGFTESLERVLGWGRTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXI1</accession>
    <name>A0A6A6NXI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8/S53 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_393797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXI1"/>
    <dbReference type="OrthoDB" id="3866712at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="205"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="51102" checksum="7E9A5A6C2A050755" modified="2020-06-17" version="1">MPSPRISLNPESPVNTRISPSQLVVIFNSQAQVQTTVNGLSSDTADLSNVQSILDENDASIESLFGLSPDRLRSQQARLSFPESVPDLSSFYRVKAPEDKFEQIASALRAVPEVKAAYVRPGASAPLIFKPTPPAFADAPAATPDFTSRQGYLNPAPEGVDAKWAQTQPGGRGDGIRIVDCEWAWRFSHEDLRVNQGGVIFGQQGDDDNHGTAVQGVVGGDQNSYGVIGIAPNSTFFGSSFENQDVATTIKAAADILNSGDVILLEIQISGPNAGNWIAVEWYPDILAVIRYAVMKGIVVAEAAGNGGENFDDPIYDQPQPGFPSDWRNPYNPSNPSSGAVMVGAGAPPPGTHGRNYGPDRSRLSFSNYGARLDAQGWGVEVTTTGYGDLQSDSNPDLWYTDQFNGTSSASPVVTGALLCLNGILRSWRGVTVTSEQARMLVRQTGSPQQDGPNGPASQRIGNRPNMRQLVPAAQALFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXT9</accession>
    <name>A0A6A6NXT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome-releasing factor 2, mitochondrial</fullName>
            <shortName evidence="5">RRF2mt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor G 2, mitochondrial</fullName>
            <shortName evidence="5">EF-G2mt</shortName>
            <shortName evidence="5">mEF-G 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MEF2</name>
        <name evidence="8" type="ORF">BDY21DRAFT_287763</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXT9"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000106">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000007">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000514">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03059">
        <property type="entry name" value="mEF_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030851">
        <property type="entry name" value="EFG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="43"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="604"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="657"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="52"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="899" mass="95874" checksum="F81EAACF15D23A93" modified="2020-06-17" version="1">MLIARLWPRGRVSVPLLARTRLFSATAVRQSAPSTGPDDDTLARTRNIGIIAHIDAGKTTTTERMLYYSGYTRRIGDVDEGSTVTDFLPAERTRGITIQSAAITFNWPPTTVSTSSSQSHLPSAPRSSTPHTINLIDTPGHADFTFEVVRSLRILDGAVCILDGVAGVEAQTEKVWAQASAYAIPRLAYVNKLDRDGAAFARTIKEIGVKLRTWPAVCQVPWWEGGRGRLLGVGDVVGRRGMKWERGGDGRDVQVVEMDELDRREPWLAKEIERGRAALVELLSEHDDEMVEKFLEAGENHQAIAPSDITDSLRRVVLHHPQKIVPVFGGASFRNIGVQPLLDAVVDLLPSPGERPDPEIKLGQKTSSLQALFSGELELPGPAPEPKKPKALFKPTPKALLAPLQACALAFKVVRDPQRGMLVYVRIYSGTLPRGAALYNTNLHQTERAQRLLRMYASDAVDVESLGTGTIGVIPGLKHARTGDTLVAYAGVNPKTGPPDPIRSLQLRPIEVPPPVFFTSVEPDSLGEKRSMDEALGVLLREDPSLSMRVNEESGQTELAGMGELHLEIARDRLIGDFKAKARTGKIDIDYRETITVPSRLVTERRESDIQGKKSVAECSASVAPASDVPTASSTSSDDITTTIPLDSSNTLTIHHAPPPSSPDPSLPPHLLTPLTSATSAALSRGPAHALPTHSIAVHIHLPAPLLLTTPDTVAPAALSLAARAAVRTALAQASAAGANSVLMEPVMLVRIAVSERDMGGVVHDISAARGGVILALDESGSGEAAAGASASSASNDAAAAAADAADAIDPHRIYAPPDPFTSSTASASADLGAAVAQGLTQQRTVTARVPLKEMVGYLKHLRSLTGGRGTFVMSVEGFERMGAQRERSVLGEIRGEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXY8</accession>
    <name>A0A6A6NXY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_48565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXY8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="124" mass="13496" checksum="20A6C4D892A08946" modified="2020-06-17" version="1">MLRGHSRRIMELTEAHTVPLCIPLDTSCTGSICHRYFAAPVSLLETNRRLHSPAADFSTRPSDPNGRRASNAKSASEPSRAWLGAGPDLDVAIIGALPPPRLPDHLPTRVVASGHTRELRLVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY03</accession>
    <name>A0A6A6NY03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_347985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY03"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19354" checksum="7BD4181B136CFD61" modified="2020-06-17" version="1">MLYRYLNLAPPPLAPSTSKPSRRCPHPFIYQHLLTPSGPPSLPLPAPPPSYTNQLPTSSQPSASRAPRYLRPRSTLRPRPCLRFLIRTPLVVSVARQWCAASRRGRWAGWSSSGSEVGGGPTGSVSGPGGGGWDERGRESRWAGELGAENVFLFLFFFAFAAVACAGAEWTVGRNFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY12</accession>
    <name>A0A6A6NY12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sarcosine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_54463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY12"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF37">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="5"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="453" mass="49735" checksum="7137E821C3A877FE" modified="2020-06-17" version="1">MARSFVIVGAGNFGAATALELVTQHPMADVALIDTSPFPNPQAASHDINKIIRPDYSDPAYTRLMAEAMPLWRASPLYSAFYHETGVLRADPSHFSDACFDSYDVVGSKTAATWLSVDEVRRRWNGVFRHANLDGVDKCYWNPKSGWAEADRALEAVIRDAVSRGVRYYSDGVQTLLIGADGTCRGVRLKSGAEMLADSVVLSAGARTALLLAESAPDNREIQAGDRIVATGAVSFYATLEGVVRDKFREVPVFKSCLKQAKGESISLASNGILKFNCDLSFTNMGYHVASGQLMSIPPEGIGQGLWNPSNFPQALKDRCKQVLANLYGEMVDGVEIEAYRMCWDATTPSHDFLIGPHPHCKNLYILTGGSFHGWKFLPIIGKYTVQMLNGTLEESLQKKWSWTEGCLPWEGHKANPTYQLEADLKDFADCLGQEINTRAPHEGLTGAERAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY89</accession>
    <name>A0A6A6NY89_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_287945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY89"/>
    <dbReference type="OrthoDB" id="2338662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025391937" description="Glycoside hydrolase superfamily" evidence="1">
        <location>
            <begin position="16"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="63304" checksum="C2AE2E449A2EF8ED" modified="2020-06-17" version="1">MVLGLLLLGRLSASADDPFNNPPGVDIWCGKAYRPEDAAFDPGGWLNAPEPSRFLLLDLRVFPRMSVYTADDSEGSFILEARTSRTRGIPYCSGNIQRHDVFSVDPVELAFEVSDAETGRTLVTGLEAPALSISHEVSISIGDLMPRFAPYTINVKLILPDCDQIYTTSTKIFRLPRRDDGGGVTKIDQLYGGLMVQDYLSNSTEWKPLFPFSYYVSWGGWLEQDLTQVDAFKAAGYNIIHVVPGGGYPPVNWTTFEQFFDLCDELGLWVMYDLRHTYQNRTLLSDQISRFASRKSLLLWYTADEPDGHCDPLEAPKTALGRIRELDPWHPVSLCLNCANFHYEEYSAGADIILSDVYPVAVNTSYSEVYGTVCNTTYGCCGCDNCEGRLSDVSDRLDAFRRYQDWLGTAPPKSFWGVPQAFGDEMFWRRNPTPEEEVAMVALSVNHDAKGIVGWIYPTTDSIAAATRALARVVTSEEITAFLLGSSTQSLEVHSPPAAVDAAAWVRESKMLVSVVNSGRATQARVSIILPEMVVGIAASKWGDGSGWKAAGRELSRNGLGKYEVDIVVLDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYG2</accession>
    <name>A0A6A6NYG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High affinity nicotinic acid plasma membrane permease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_346034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYG2"/>
    <dbReference type="OrthoDB" id="5298304at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901604">
        <property type="term" value="F:dethiobiotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015295">
        <property type="term" value="F:solute:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905135">
        <property type="term" value="P:biotin import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000399">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000278">
        <property type="entry name" value="Putative MFS transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF33">
        <property type="entry name" value="VITAMIN H TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="533" mass="58286" checksum="78B591B8FAC1AE20" modified="2020-06-17" version="1">MGDDVIGNPQTCRGTPSDGAKLHEFHQDVEVAVENVDIARIEKVYNKLDRRIVPAFWTLYFLCSAIRSNIGLAQTMNLDSGHDLSSVLNITPKQVSTGLALFYVCYCVFDFPSNLIMSRLSPHVWMSRIVVAVGIVGSCMAAMKAVWSFYLLRLLLGIVIAGMWPGMSYYLTLFYPPFRTGKRIGRYFTAAQVSAAVVGLVSAGFQKMDGLGGLVGFQWMFLVYGLVGFLVGVSLLWWLPDRPIRPGQTGKRTGWRKFIPESKPALTGEDARVHYEDLTRVYHRRPWTLQDLLAALKDWRIWPLTIMYFGVVGVGIGVQNYGTVIIRGINPDLTGVQLSLLFAPIWIMDLIAILLVTPLSDRFHHHRALFFSVPVSLQIAGLLVTTFAGSSSNSWARYGGLLVVGFGLGPTVPITMTWTNEIFQTRHGEVGVAAASAVVSGLGNCGSILTTYALYNGWPSDADGPHKYRKSNLVMVGILCGSIASAFAMTVLLGLFGIAKKKISGLSSACESEGVAVDGAARREIQQRGFGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYG6</accession>
    <name>A0A6A6NYG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Non-haem dioxygenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_372441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYG6"/>
    <dbReference type="OrthoDB" id="627829at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-haem dioxygenase N-terminal" evidence="1">
        <location>
            <begin position="34"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="27432" checksum="6630F60988EDE955" modified="2020-06-17" version="1">MQTTLSSAADVTRLDVAPPASSMSATTLLGLSLLDADDQRARVQPLHNLRAALYDIGFLYVANHGVPRTIIDGLGAYLPALFGLVASTKTALSERNWPHFLGFSGFAEEETIAHDIEYPGGALVAALSYRFVDLVEEAFGITLGTLDDFARENGASPWHRIKLTKHLPTAGKEEGLEVLNADGERIAAPTLKRSFVVNFGNALEAATEGMMKATVLCVGSALRDESFSKLFNLNTGGSREIARQEQRALQISSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZI7</accession>
    <name>A0A6A6NZI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZI7"/>
    <dbReference type="OrthoDB" id="5405654at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42053">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42053:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="235" mass="24484" checksum="32291389CCB3B81C" modified="2020-06-17" version="1">MAAATATSKPQAPPISTIKTPLSATYPSELRSPLPGSPAFIKREEGALKTPITPPNAYVDFLKAFSPSILTPLPTGSSSKFTFGDKTPAPSSATISEKSSPLPSASQPPSSATSACSCAATAGEGTKAARPSPKITIPPSPFTRPMSARTASPRGYNGCPSPFSPSSARSPLSAHSVQSPFSATLSPRERDEAGKPGRQRAVSVRQVVTRTVTYTRTPVTPLEPAPRGKRRKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZL8</accession>
    <name>A0A6A6NZL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZL8"/>
    <dbReference type="OrthoDB" id="45930at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="548" mass="59775" checksum="C746EFE1CB34AD1A" modified="2020-06-17" version="1">MLDAPRRWFRRNRTNFAIGAGVIGGAYLAGQYVLGKISEARQRLSDDRIARDNLRRRFEQNQEDCTYTVLAILPTASENILNELPVERTLAELQRQRAERLARSGNVSVASSDVAPSITTTEDDTARSEGFVHASQQIANGEGKSESAENGNGSGSGEGESTIKATKKTKAQLWSELKINSITRAFTLLYTLSLLTLLTRIQLNLLGRRSYLASVVSLASPPPPGGPNSSAAGATRIELENRDDDAALQDTYCSDFDTNRKYLSFSWWLLHRGCRDIMERVKEAVETVFGGLNPREEVTLERIGELVLEVRRRVEGKDVGERRNMKWLPFLLPPTDQESYVLRESGMTTSSSPPPTPSPDNAPNVDVPPALRRLLNETSDLIDSPNFTHVLTRLLDACFGHLIDIKLAQLVYKSTSSDALSGSTPASSISPQTPQVRASRTRLADVLPVFTRQAHVIGAAGDTDVVRNEYIDVLDEVGELRAFAAVVYSSNWEIEGEGGSGDTWKEDDLSRPGTAGTDAEGPGTTPVGGEESSLFESAWGKATASSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P063</accession>
    <name>A0A6A6P063_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P063"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="544" mass="59394" checksum="B34CBDECB998C3B3" modified="2020-06-17" version="1" fragment="single">PRRNGCGEDISPARPSGVSLAPRFTYPEQANCGIEFNEAIRKLRKLGPKPQKPSSQRLAECLERKFTEVRMIVPELPEDAVGQPPAKEEDYRLLDILVFEGGAHNELRRAFAQLSLAAGFNQSNPRLLRAMLYTKSLKLPKDSQGSIRAYVRVNFHPKSQTTARAAVSTGLKLFAIGMAYSSHVMPILLAFVQRHIMSMEFSDVMAAFELPALSKAKEFATSLSSWMDTAWECYNAQGMSHAMHISSGPTFALLSPNNNANPILSETRPQKRRRTSPLAITGTGASGSAEIASKIRQNEDVHVNPEVDSTRGNDTTWSDRLENRAAGNTTEAIDADTSALTMDASSGTPSSDVAVWTPRTIQPIAGRRPNRQLIGRGISGPARNSLHRLPELDSAEGQRGSAVQVKSEARESARGGVSELRQGHVRFSPRTADLTQGSGGWNHVDGREKENVTKGTDKGVNSRLEHGDGAAATQQSPQDFPVAPNPHSSTYQTHADSPPLLGTQLHGESSGQLPGERRSPTSRLSDILHYEDDSSWWRDLWGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0J6</accession>
    <name>A0A6A6P0J6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_337782</name>
        <name evidence="7" type="ORF">BDY21DRAFT_340245</name>
        <name evidence="6" type="ORF">BDY21DRAFT_345456</name>
        <name evidence="5" type="ORF">BDY21DRAFT_351627</name>
        <name evidence="4" type="ORF">BDY21DRAFT_355811</name>
        <name evidence="3" type="ORF">BDY21DRAFT_357067</name>
        <name evidence="2" type="ORF">BDY21DRAFT_359446</name>
        <name evidence="1" type="ORF">BDY21DRAFT_359697</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001715">
        <property type="protein sequence ID" value="KAF2452266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0J6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="53" mass="5899" checksum="0EDC282078B8E7FC" modified="2020-06-17" version="1" fragment="single">MKGCSINKTLREELSTSRRACEEKVGDSRLGGCRHVNQLRTQQYGGCAVSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0S1</accession>
    <name>A0A6A6P0S1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_344269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0S1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="237" mass="26006" checksum="49E60C6F98ECDE75" modified="2020-06-17" version="1">MLFERSFIPRLGYLQNPSLPSPHNTPPSFCVSGLAPSVARPSLLPPPAAQREWLLPSASPSSSAAFGLRDLPSTSASDRARIAGSASELRSVLRTCFVYVPTYVHMVWEAHIVRAGAGRAFLFYFSSVGRLGALAAARRGGLQKRGSGTCSCVRSGRRCANKGYVHFHWRDWAQDGAGDATLSDGKRTLIMFGSTFVRHRGDGRDKRTKKSECLKRTKTKNEKGANGWTKYLLEYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P192</accession>
    <name>A0A6A6P192_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_16330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P192"/>
    <dbReference type="OrthoDB" id="5398515at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="537" mass="58981" checksum="8C1AF08CFE25E63D" modified="2020-06-17" version="1">MPSTPPPPEGRRVHTPPAPLHGPKFDEWDPYSSPRRSSRVAAQQEQKVKQTSSVENTPTRSGRAAASNSLGEPSSPTSSRKRGGMMAAASGGSGGLRSGGSAHKHRISPPPMSPSKRARATPRKSGAKHLLAQEYTESDSANEDEEAPPSMRKLRSAPAATMTNPGAMFPTPVKTPNKPDGEDETPKKAALSSTARVLFPSSRTAKPEDAMPTPRRRRKHLPFTLGSFEDEVATQDGDQIQIYTDTKERIPELDEGEDNPFVTPKGRKTKQHETPKRKKERSKEAEEEEERMQERVRNNEGLIYVFRGKKVFRKFEDAPQNNASREVDEAEETLSDRELRRMAGSPNARRLPRTDYKPRLLWPSEEQRREREAAAAANQDDDEEAITEIDSDSAERSSNVAPATTPTRKGTKKIEVVPVPDEPEPEAETETHANTLPDPFNTSGPSRSARKPRFPRMQLDGANDDDDFDDAAAAEDKFATAASSSPSAVATGATRGKGKKMSPFDQWRRSKASVPDVKGTKREGSSLQRGAAAKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1L9</accession>
    <name>A0A6A6P1L9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1L9"/>
    <dbReference type="OrthoDB" id="5386574at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021582">
        <property type="entry name" value="Aim21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11489">
        <property type="entry name" value="Aim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="681"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="870"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1176" mass="122496" checksum="69D9442D1869AF8F" modified="2020-06-17" version="1">MSMPTVPPRPARTQNQAAGPTASMDVPRVPPRPARRPDRSASPNRNTFARSPLNDPSFVHKASHGPNGLGSKRELGDSPPRRPPSVTLPSIGQEGQEYASLLHLTTGGSGDHDHDHDREKDAVAAAAPGDKMAYADDDADADSVVGKPEQTKNVAGDLPLYAPTASMPKSMAKSRIATVTRTDSSQAEAAGVGKGAAYDGADDSSSAAGGAGNKAPRPPSSTSGGGGAASASGFGLGLDATRSSSSLGTRPQSIYKEDEEHGIPEIGIQVPMYPNAGDVQAPTPAPGQAGPFQTSSGSVSGGGVSGAGAGGLGSGDASAPVPQRPRHQRTKSGREIFTVPPGSYGLHGHGVEPRHPLEKKWYEKHPEALEGEYGPGIQENRKDYHLSSDDLNKLVRETARNGVGMGSGVNAMSTPDEMIGYMAHEEFASRMASPRPPSVAKGRSGSSQTHAESPLRKASFPINELKKKTSTTSEAGAVESEAEEDVIHIDAPQKSVDWAPSVPGDEHEDRETPILAEDEVAKHPEAEYLQPAVSPEPEGRRSSMYTTEELDALRPKSSSSRPTTRPTSRNNSLHSPPAGMSRFQSSEDHHEPLEHVKEYEPLFPEEDEDDEDDEAGQKHRGADGGKGGSGRKGEDGKVPRPALPARHYFPSKDVWEDTPNSLQLQTVVDHLPSPTDEKKAAAAFEGAGAGAFETPEQEQSRKRAMPGAKAASDKQLRPAGEDEDEDGDGGHADFLSAHQASRQGAWHNRHLRRVLDEEGGAGGRRPGMQQRFPSQDIWEDTPDHHQLVTVVRSPPSVEEQKEQQQLKEQQQKEVAEDQRQAEAAMATATAATAKPSVPPRPPRKQPSGDAGPDKKAPPSVPERPKPSVPARPGAAARAPTKRSSAAAAADEEAAAPAPKPKPAAPARPPPGGKIAALQAGFMKDLNSRLQLGQQGVRMPGASEKGEARGGGKESEREDEQDEEEEKRPLGDARKGRARGPARRRRPGAAASSGSRSPGPAAGAATATVAPKGAPAAADGQSRSALRLSFAPVWTALEIGEDGGVGHGAEKKKAPAPAPAEAEAEDLATPKAEVPLASAMGGSAVAEPAAEAEAPVEVDEEEVSEEDGEALRKGAGAAKDEAVQTGRKDVAIGAGVGAGEGMGTGMEVGVGEKLTAFVGGKAPDEGDVVVRGKEGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2F6</accession>
    <name>A0A6A6P2F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dimethylaniline monooxygenase (N-oxide forming)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_285460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2F6"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="630" mass="70432" checksum="87D6BC9BDEBE65AD" modified="2020-06-17" version="1">MAAAAVALPSVSRVEPGSFTLDAGNLPLASADSKVDPDAVVSKWLESFQKVLENKNFDELKNVFLPEAYWRDQLCLSWNYHTLKSSTNMVPFLKAHTKGCRLFKLGIDRSSSSPKVAPLDFLGDIKGVVSFITVETDVGRGRGVVKLSLDKTDNQWKAFILFTAMHQLKGYEEATGPRRPQGVKHGHNPGRKNWKERREAEVNFADGSEPTVFIIGAGQAGLTIAARLKMLGVNSLIVDKNERIGDNWRKRYHQLVLHDPVWYDHLPYMPFPEFWPKFTPKDKLGDWFEQYANSMELNAWLSVQLQSLDYDEATKRWTISLERAANGKKEKRTVHPRFVIQATGHSGEKNFPSHIKGLDTFKGSVLCHSSEFIGAKPNSAGKKAIVVGCCNSGHDIAQDFFENGYEATLVQRSSTYVMSSEAGLEVLLGGLYEEGGPPTEDADLLFYSIPNAVLKRMHVDATKEIARRDEALLDGLRKAGFAVDQGPEDSGFFMKYFQRGGGYYIDVGCSKLIADGKIKVKQGQEIEAVTEKGLRFADGSELEADEIVFATGYSNMRGTCRKIFGDKVADQVKDVWGFDEEGELRTMWRRTGHEGLWFMGGNLGLCRYFSRMLALQIKALNEGIMKYDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Y3</accession>
    <name>A0A6A6P2Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biogenesis of lysosome-related organelles complex 1 subunit CNL1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CNO-like protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_284382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLOC1S4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Y3"/>
    <dbReference type="OrthoDB" id="5424991at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034455">
        <property type="entry name" value="CNL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39145">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT CNL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39145:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT CNL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="148" mass="16359" checksum="029BA22CA11A21AB" modified="2020-06-17" version="1">MASPAPSVPDTQLGLSQAEVQLLRQHQSAVGSQLGGSSSRAASNASSHGRLLVDPSSLQALSAHFDRLMYSIQQRWQALHAQTQAATTQQYDRAGNAIEMADAEIARFHEILRQIDELQVEFDKVRHISEIVKGYRARVEAIDRRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3B2</accession>
    <name>A0A6A6P3B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_215862</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3B2"/>
    <dbReference type="OrthoDB" id="3232309at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466:SF1">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="213"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="450" mass="49962" checksum="D6B2293AFF9C2DD8" modified="2020-06-17" version="1">MVYSLNYRRPSFVPNSRASSNGEEMPGSSHGSVASGNSGMSRNIPDALSFDRIISGGTCPPCTIRDFMNYSMYIAHTPENLQFFLWCRDYEDRFNKLPESEKALAPEWVPSQADADNLASHAQRNPRVSPEAAAAFRGTGFAATPTASDSERINPFSTPSQSPSVASRGYDSTDSADLDSPFGAQQKVDHAKNAATTFESAGLMKPFTIQPYREEINRIISIYVSKHSPRELNISSKERETLLKALEYTTHPSAFTDVKKSVEWSLRCQAHPNFIRWSICNGNKPRVLFARFLGVAGIIGGFIAAILLTLSSAGRAWRVMSLIGFFIGIATLIAAWKGMCVVLHGMHHRHLRPWELFASEDEDPEVESKKGLSSESLLSNKSNSFEDEPWVARYEKRNVVRKVFDREVWIQEPALRQIQDTIFIQAILGAFVLSAVAVGVFCAFPAGNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3C5</accession>
    <name>A0A6A6P3C5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_370752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3C5"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000100">
        <property type="entry name" value="Glycosyltransferase family 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF5">
        <property type="entry name" value="UDP-GLUCOSE,STEROL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="292"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="615"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="244"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="828"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1060"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1146"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="829"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="847"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1082"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1195"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1249" mass="134106" checksum="206AB2F7E2571694" modified="2020-06-17" version="1">MADTADSRGHGHTAIADDDDIAKRSTSEPSRTANKNATSPPPPANNPLNRAETAPEPRPSSEPSRPPAAEKKQPAKRPGPPPKSGTALDRTAGILAGARAGRQPDFGRARPTELQRAITFQLDSDEDEDPTSSDEEWEGEGGEERSGGQGRKVSEREASTGEGSRPGAEDGQKATGRGKRRSKRKSRDWPRFDRFVVGNDAFTSRGRVSKRDGRLKISVSETANRGYLAKALGTGLRNHLKESIREARKGDEGPDQGEADDEEKRRAKDEAEGPAPGPAEAAAAVVPPRLNVVVMVIGSRGDVQPFIRIGRILKEQHGHRVRIATHPAFKDFVERDAGLEFFSVGGDPSELMAFMVKNPGLIPSMETVKQGEIGRRRAAMFEMFQGMWRACINATDDETDRENIKMMGNKAPFVADAIIANPPSFAHVHIAERLGVPLHIMFTFPYSPTTHFPHPLANIKSSNVDSEYTNFMSYPLVEMMTWQGLGDLVNRFRMKTLGLEPVSTLWAPGQLYRLRVPHTYLWSPGLVPKPDDWGPEIDIAGFAFLELASSFEPPPELVKFLEAGEPPVYIGFGSIVVDDPDRFTRMIYEAVRLAGVRALVSKGWGGIGGEGTKPPDNVFLLDNTPHDWLFPRVRAVVHHGGAGTTAIGLKCARPTMIVPFFGDQPFWGSMVARARAGAHECVPYKRLNAQRLADGIEQCLTDEARRNVRRIADSIAREGDGAANAVRSFHRALPLRGEPSLRCAILPDRVAVWQLRNTQLRLSALAAELLVARRQLRWQDLKLLRVYDWNDFDGPGEPITGGGAAVLYSMSQAAKGVGLVPLHMTRSVKERKKHWDKKKRAKKKLKQKEQQEQGSEKDGPVENGDVAAGPPQNGRPTLPARNSTKMSALSADPENYVVEELAYDAGHGLSKTGKAIAKAPMELSLAVAQGFHNAPRLYGDETVRRPVRISGIRSGLRAGKDEFLYGVYDGFTGMAYHPVRGAKTGGALGALTGVGVGVGGLVLKNVAAVLGPAAYAMKGAHRQMRRGRAPTAFVRRARVVQGHKEWRALLEAADGSRALKRSGSVPADGLEVDDKGRGAGAATSSGNARPSSSPSSSSSTTTPASASADLAALTARLAAAAPALAAARAAAAARARLRPRLRHELRARRAHAPAAAAAEAAEAGEAGGTEGRRRPVGDAAGGLGHEDEAEAEVEDLGRGEGWKAEGEERAWGRRGAGGDGDGDGDGGERAAGRRASGPDARDFAPRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3J0</accession>
    <name>A0A6A6P3J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3J0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="78" mass="8525" checksum="9DFAAAAD62F0A8F6" modified="2020-06-17" version="1">MFLLDVSRECVLAWGFSLSLFIYAFLVSDSYLLLLVYSTGGVVHVVVLSAGTCLDTRTMAGRSNMCTKMLVCNDVGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3K1</accession>
    <name>A0A6A6P3K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_205624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3K1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="16969" checksum="1359C054B5D3C4FF" modified="2020-06-17" version="1">MINTYSTQSESLNHRHPVAKHRVPWSPSLLRLLVSSNGSATSFFSFASRFVLSSAARRPHEPMYARPCAWAQSEGTHARHRSRQISAENLKRAETSLCTISQDSSRRSLAVAQRGEASIVDIPTSPSHHFRNERTRKLVAHPRGQGEAQTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P404</accession>
    <name>A0A6A6P404_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_210707</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P404"/>
    <dbReference type="OrthoDB" id="25767at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF5">
        <property type="entry name" value="TRNA PSEUDOURIDINE(38_39) SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="328"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="201"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="641" mass="72480" checksum="01763B6AA616ECE8" modified="2020-06-17" version="1">MRTAVPPIFQPSFRNNLWRIRSHLLLLPDSSQLWTYFAKQRYSSAMAAAAPNEVDYSSWSNEALVARVTELEKRLKETNAQAVNAASPNNPPAKKIRRKVPNRLIDPSKYSTRPIALKFAYLGKRYNGFEHHMNNKTRLPAVEEALWRALMKCRLIFPIDKDGNIQQGDDGDINWNGCEYAKCGRTDKGVSAFGQVVSLKVRSSRPPEHDGSEKSAGNARLYASADEAESTKQAEEAKPRKQWDPIKDELQYTHMLNKVLPPDIRVLAWCPNPPPGFSARFSCRERRYRYYFTNPAFLPVPGRKGLYSGQGERTYREGWLDIDSMQEAAKLFIGEHDFRNFCKIDPTKQITNFKRRVYHTEIKEVQRSEGPVALATWPGFRQPGVDEMFQQHQEESLSAVIDVQAELDKITSLAPSDPITAGSAFPRPTPKLYAFEVQGQSFLWHQVRHLVGILFLVGQGLEPPSVVSNLLSVEKTAGKPRYEMAEDIPLILWDCIFPDLKTKSREDSLTWIYVGDEQKGESPVKGGASGKFDRMGILEDLWETWRERKMDEVLAGTLFDAVASQGRKRDYGAEPLVPGQDVRRSAKVFHGGDSYKLSGKYIPVMQKEKMDAPEIINARYASKKGLNGGDIATQCSDEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P453</accession>
    <name>A0A6A6P453_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GTP-binding protein-like protein GUF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_341420</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P453"/>
    <dbReference type="OrthoDB" id="1074at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000078">
        <property type="entry name" value="Elongation factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="64"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="73"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="191"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="662" mass="74040" checksum="61A83ABD1DD851DA" modified="2020-06-17" version="1">MRCSPRAAQPVLQQWRAPLLRLRRPRDAFRPRMVPGSAHLRRSYATAAREPGDLEKRIAAIPIERYRNFCIVAHVDHGKSTLSDRLLELTGTIQPGQNKQILDKLDVERERGITVKAQTCSMLYRHKDADYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAFAQGLELIPVINKVDLPSADPNRALEQMHDTFELDPSKAVLVSAKTGLNVEAILPTVVDHIPAPVGETSKPLRLLLVDSWYSNYKGVILLVRIFDGQVKAGDQITSLVTGLKYIVGEVGIMFPDMTPQTVLRAGQVGYIYFNPGMKKSQEAKVGDTYTKVGSEKEVELLPGFEEPKAMVFVAAFPVDQSDYEHLEDSINQIVLNDRSVTVQKESSHALGAGWRLGFLGTLHCSVFEDRLRQEHGASIIITPPTVPFRIIYKDGSLETISNPNLYPDDATIHTRVAELQEPYVTVTITLPEEYLGRVIELCESNRGTQLELTFFTAVQAILKYDLPLAQLVDDFFGKLKGATKGYASLDYDDAGYRKAQLQKLQLLVNKEPVDAVSRIVHRSQAERLGKAWVTKFKEHVERQMFEVVIQAAIGKRVVARETIKPFRKDVLAKLHASDISRRRKLLEKQKEGRKKLRAVGNVTIDQKAFQAFLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P459</accession>
    <name>A0A6A6P459_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF159 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_283922</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P459"/>
    <dbReference type="OrthoDB" id="2111841at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106300">
        <property type="term" value="P:protein-DNA covalent cross-linking repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="373"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="46450" checksum="0F99FAD525CA0D51" modified="2020-06-17" version="1">MCGRYALALRPSEVRHELESSQMPCDDAPADGAVKQSHNFAPGYYGLVYRADVPDRGAGDTDNKVGESADMHEVIKEIEAQKSFRHPKIGYKLQAMKWGLIPFWTKRTPDYGSVMRTINCRDDSLIENRGMWTTMKRQKRCVVVCQGFYEWLKKNGGKEKIPHFVKRKDGQLMCFAGLWDCVKFEDSDEKLFTYSIITTNSNKHLSFLHDRMPVILDNGSEEMRKWLDPARTEWTIDLQSLLKPYGGELECYPVSRDVGKVGNDSPSFVIPINSSENKSNIANFFGNQKKSAKREHAGVREQERKDESTRYIARPKREGSGKTLSDSETAGETRNDSGAVKQGVKRELSDSGSPSAPSIHADKASKVSPNKGPLQSPSKSIRTTRNVSGNAKQTDQSPSKGPNGTRKITAFFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P474</accession>
    <name>A0A6A6P474_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_420731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P474"/>
    <dbReference type="OrthoDB" id="5355510at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="526"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="562"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="583" mass="63303" checksum="C3886DF6F05C9F20" modified="2020-06-17" version="1">MPAFTSSTFHTQPNFPLQRPSFGPPARTSRPPPSYSANDSTATATNTIALASNSNTEVYPTLRPQFYLTRGPNHLTPLVAADELPLSVQLRGVPRAMTAELAQVMGMTCVGEASGTGRVYGLESGVLGEVGREHDKKEQALDPAEQERNDKAREGSSAQRPDVQSLSHCHFYCALPYTILARKPDPEKKEYCTYWIRTGECDYTQQGCLYKHEMPDKATLARIGFRGVPRWWAEKHAVRMRPILSENRTDEGARSSGATMSWRRLTTTPDALRQAPGKVLAKEDNNTTSGEESSEKESDSESEDASARDVTVKNVKRQSGQHLRSNPTAPKDSKFYFSRTAKLKDADPELVHVQSSSAVQEPRSNRALTCADIKFPALVPQKSRMVTGESSGDDSLIELQMPGAHESNKNLNHQKQHRVEIAKESLRPDVTIASKERTTAGKSKISQPASQAAPISSDCGSLLDIEPESCAPSSANIKSAAGQQVSTETLIGFLAKQGLLKDPNVALKQLLGSAASANNTADLKTNVDKEGKAASKAEKSRGMLASKYADNSEEVAEESGKTKRKAVNQKVAKKGKNTAAIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Q4</accession>
    <name>A0A6A6P4Q4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_420270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Q4"/>
    <dbReference type="OrthoDB" id="2387925at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="58681" checksum="4789708A04867D9F" modified="2020-06-17" version="1">MQPHRDMSARRDPGASALVSFIVPRAEVKRVKTELERREKFDRSAKIRPNTDQTFAIPSSIEWPLAAPDDVESFRARLLEGIGLAALQQKIQLAPRRGAQTHAHDASSHLGQNPLRAAIAAWITTLPSSILPSLNIAPSALVSSFPTTHSVYPPLLLLPAHAFRSSPWPTLLRHIPSPHLATLYAGLASAAGATAVAINAPIPASCAASLGATEASNSADKPPSRSAPPSPNLLRTPSGLTPLHNFPSPVPLSASASSPSFLHRPPPAALRAALWAHTTQHGIAQTWAPAYTMFSRGNVREKARLLEVVEPRVARSPSPGRAGAGPEAGNADVRFAAVDLYAGVGYFAFCYAKAGAEVVLGWDISGWSVEGFARGAEANGWVCGRVGEGDDVDLGIVQALERRRDGEEDEVGQGEVVGSAVASKRRPRRNGRSHEPLLLAFHESNGYALSRIERLRSSIPPIRHVNCGLLPSSRGSWATAVEAVDPDAGGWVHLHENVGVHDVNARADEAVGALRTLLAAARKGYDEGGEPFAVVDTLKVIHDVSKFSAVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4V8</accession>
    <name>A0A6A6P4V8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_199203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4V8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="28830" checksum="4067A393FD973DFA" modified="2020-06-17" version="1">MPGVPYFSRSQCTEGTFRAFRTSLNGREEKREKEKKLKRLARSRCYRRGRACTAPPSQWRLARDATVGSLTKICRYLHTRAFSLGLRSWRLPTGMRPRHLSHREREKRVLEVQGTNGAGGGSDRTCPCGKYQRITARFTQLFAPTGLAGDAIALRARPGRKGALESQDVVPRRHRGSGPMMASRAGCTWILALARIPPGWEDRPVRGQPAKRRRRTRVSENEGGSAPTPLAHGFAWYIAAAKHLHISFDSPAFLNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P528</accession>
    <name>A0A6A6P528_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_300672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P528"/>
    <dbReference type="OrthoDB" id="3914935at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="490"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="511"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="60817" checksum="C9C679C0CB7DBE8E" modified="2020-06-17" version="1" fragment="single">MGKPQPAAPPRWLVHLRFRTESRDFAPLTLHSESSRSKENNSGIQLTVLIGQVNTSSPNTMPARSDGNKQRQDERIINTNSFSILSKRSVHRLYFPDQPDHYALFTTKFERRAPLINRGYWLRMHAVRAGVLRFLGLHHGASLSSSPSQPVRVVVNLGCGYDLLPFQLLRERPELCENIVFVDVDYPQLIQAKADIISRTAELSGLLINVDTSGSDKATPLRSQQYVALGCDLRNLSLLESFLTAGLGRPACAFLFYAEVSLTYMPVADADAVIRLASSFHNSHFLLLEQQIPSSTHPFTITMLDHFATMGTPLHAPLTYPSLASQLNRFARLGWRGPVRARSLWNYWLDRHAVGADEVRYVESREAFDEWEELGLFAGAYFVLCARNGGGGEGEGQEKAEEWVDLGGTELETGENESQDDVRTGPGLRFDFHPHSTTGDGETNASFSVRRRFAAILLSPSPSPPPDAHTLQAFAHHAGLGPRNTRVTTSTIYTPLPGPTTTTTAPSFSRPSPPQPLPPPFSNPPLARGITHHTITPIPYNPSSSSVSSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P537</accession>
    <name>A0A6A6P537_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribonuclease P protein subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_300715</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P537"/>
    <dbReference type="OrthoDB" id="124041at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.210:FF:000005">
        <property type="entry name" value="Ribonuclease P protein subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027081">
        <property type="entry name" value="RNase_P/MRP_p29_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR027081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="250" mass="28505" checksum="44343DEAAD353E43" modified="2020-06-17" version="1">MASSAPDPANTAKAGFVKELLQRAHSPSSATYVYDEKIRDRPLFLRPTDVDVANARTRRQRERARKDALRRKSQKPRPFSAREKRALGVHDIPSDQQKYAIFEPLHRMWCAYMRDILGLQKDQAEQGIASRAHVTPETAGPMLVSADFHGAELEVVRCRCVDRVGIKGIVAKDTKFAFELITRRNQLKLIPKEHTVFRFEIPLGESNEESSTENQNPPKRLIFELHGDQFIVRAGDRANKKFKAHVPKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5C3</accession>
    <name>A0A6A6P5C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_282624</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5C3"/>
    <dbReference type="OrthoDB" id="287393at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="130"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="344" mass="38980" checksum="8293101BD2F5B3E4" modified="2020-06-17" version="1">MSARKRNEWLEAGLSDEEDQDDGYDSEAAEQRRRVAFYGRTSKRRKVNSDFEGSDGDDDGVASSAQICEKEVGNLEDTARTGQRIELPDDDFVDPDPSVSHNDTGAPAAPYSKLTKKKLESARKKAARTGVVYLSRIPPFMKPTAIRNLLSPYGDIGRIFLTPEDAEMRRRRIRSGGNKKTKYTDGWVEFLDKKDAKAAVETLNTQIIGGKKGGWYHDDVWNMRYLKGFKWHHLTEQIANENAERAARMRAEVVRTTKENKEFLANVEKAKMVEGMKSKREGKTAGRNGLNNADEVEDTAKVESVKFDGPRRHFKQSKTKLKKLESEDDVDQPEDVTRVLSKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5P9</accession>
    <name>A0A6A6P5P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_408618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5P9"/>
    <dbReference type="OrthoDB" id="5125733at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9852" checksum="70DD10F7BA0A37FB" modified="2020-06-17" version="1" fragment="single">MKTTGDAKALKLAPYTVVHTVSVRAVDNRGAFQSYVVEEDELYGLPLFSRAWCFQERLLARRVLHFTPTQMVFECRSCCQYEFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5T1</accession>
    <name>A0A6A6P5T1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative NADH-ubiquinone oxidoreductase 64 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_370626</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5T1"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.100:FF:000002">
        <property type="entry name" value="External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.100:FF:000005">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 64 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF50">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="538"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="691" mass="77365" checksum="D8D1390EA24F9611" modified="2020-06-17" version="1">MRVPVGPAPRFNHGRSAGQFQGLLPSPKTTTRRGVSILTPRTTHRPAISRGCSSLHPRCRLSAPFQIRLAATDTTGAAAEAAVKRGRLWPLVYRGLAFTGFFFLSASSVLAAIFIYDATTYREAPTFEDISLSEYALHPRRGGPKNLPIAEHLVDDDESPEMKAQKHKPKLVILGTGWASVALLKQLNPDDYHVTVVSPSNYFLFTPMLPSATVGTLELRSLVEPVRRIVTRVKGHFIKAMAEDVEFSEKLVEISAVGPGGEKEHFYLPYDKLVIATGSVTNPHGVSGLEHCHFLKDISDARLIRNTVIRNLETACLPTTSDEERRRLLSFVICGGGPTGVEFAAELYDMLNEDLCRIFPKILRCEISVHVIQSRGHILNTYDEALSRYAEQRFAHEAVEVLTNSRVKEVLSDRILFTQKNEAGEIVIKELPMGFCLWSTGVSQTEFCKRIAVKLEPQKNRHALETDTHLRLIGAPLGDVYALGDCSTVQNNVSDHIVTFLRTLAWEKGKNPEDMEISYSDWRNVAKRVKTRFPQAADHLRRLDRLFERYDADQSGTLDFGELHALLRQIDSKLTSLPATAQRAHQQGQYLGRKLNKMAQAAPGMRLNQLDYGDIDEAVYKAFEYHHLGNLAYVGNAAVFDINGMGLKGGLLAVYLWRSVYFAQSVSLRTRILLAMDWTKRAFFGRDLMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5V7</accession>
    <name>A0A6A6P5V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_370073</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5V7"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000097">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="18"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="471" mass="52082" checksum="142D34D6CD171FFC" modified="2020-06-17" version="1">MSSYALPKSHQDLMERSLADTDPEVAEIMKKEIKRQKESILLIASENVTSRAVYDALGSCMSNKYSEGYPGARYYGGNEHIDEIELLCQKRALQAFGLDDQKWGVNVQPLSGSPANLQVYQALMRPHERMMGLDLPHGGHLSHGYQTPSKKISAVSTYFENLPYRVNLETGLIDYDKLEENALLYRPKLIVAGTSAYCREIDYPRMRQIADKAGAYLMMDMAHISGLIAAGVNKSPFEYCDVVTTTTHKSLRGPRGAMIFFRKGVRSTDPKTGKEIMYDLEGPINFSVFPGHQGGPHNHTITALSVALKQTMMPEFKQYQQQVIKNAKAFGEELTKLGYRLVTGGTDNHMVLLDLKPQSLDGARVEAVLEQINIACNKNTTPGDKSALTPCGIRIGAPAMTSRGMGEEDFKRIARYIDACIKLTKKVQGELPKEANKLKDFKAKVASGEVKELADLKAEVAAWAGAFPLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6E7</accession>
    <name>A0A6A6P6E7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_188677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6E7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17242" checksum="0FD8297E330E7812" modified="2020-06-17" version="1">MKHASRQSHNLPALNRYLTYIPQAPSHHYESTVPFSAAFLSAAAVSAILTSSRCCLVYNHYVRHRRLRRKGDGFAPIPLLGLSTRTEVWEMVAGQTTAVIALARLTVLGHLLSPSILIAWNRSASSPVPPAPVDIYEEKGTSQTETAERCIYTRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Q9</accession>
    <name>A0A6A6P6Q9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase-like superfamily-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_282352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Q9"/>
    <dbReference type="OrthoDB" id="5538558at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF39">
        <property type="entry name" value="THIOESTERASE_THIOL ESTER DEHYDRASE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="316" mass="35045" checksum="A2C8D594BB304506" modified="2020-06-17" version="1">MHARTPRAAPGVRPLVPRSRPPAPRAQQHAHHRSRRSCSSTSGSGSGSGSGAAAAAGLPSRWLADVAARLGKCVHFGLGPAQARVAAGVARDVGQDWRGLVAGSEGYLTGEGRRGLWRHEVQWGEMVGLMDVFFFGGHVNNVMYNRYAESARVNWALNYARRIDPAHAREWRELVTPRNQGLIMKSIRTDFKFPMTYPDRITVLHKLRSPPSSSSSSSSSPQSDLTLDVLILSELHRRPAARCVEELVLYDYRAGRKARMPDWMVEVLSRTWAEQEEAKVLWGGRARDLEERVRELERGSWDREGAVEDFGTGGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P740</accession>
    <name>A0A6A6P740_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIP-1 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_420119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P740"/>
    <dbReference type="OrthoDB" id="2189254at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1212" mass="130342" checksum="5090214F7E32FBFD" modified="2020-06-17" version="1">MAPSLDTDTRVADYLDDKLQTLADLDSLDELLANVRSQQGLLKQQLSEAERDLGSAKQAARDRAAEVRRRARDFDAQQRDIDEHLRLLTGSDASDDALGRFEASMGALRRLDVANAYVRLLEEVDRLSAQATAALSRSPDDDNNNNATALPPYRRLRLLLAQLRPLHAAAEGAAPHLLDHVARTAADLRSRIAAAYSAELEAALHKLGWPRPDAVLAGSLLSGFNHAFRKLLSLQIAELEADGERSSSSAGATAGGGSRELVLLPMETLVKPLALRFRYHFSGARPTNRLDRPEYFLAHATGLLAEYAPFARDYVQPLLSAAFASGSGSGAAPAWLARNPLCVDATSALVAALLPVVRWKVLKEMPRVVEEPGLLGHWVVELMRFDGEVRGEWGFEGGAVGDGGGGEEGGGEEQGWEGLGYEVLVQKGYVEQWLQGETAFAVARYQEIVEAADGGELEYESVEAGQTKPSKAAIRLVDLLETITEHYRPLPSPPHQLRFLIHLQLDLTDRFLRRLDAALEAYRTMTSPLSRIPGGSIVVAGPEDRAAVAGIHGLDRVCRILGSADYVARALGGWADDVFFAGLWSEAKRMVARAVERAGPDAAVAGTGLGARELAHRTSDALLPADGARKAAGAAEPEPEPDVDVDDMAASLFDAQRACFERLRGRAERSLHETLRLGVGEALRPYAGVTDWASLAWPATAPAGSSAGAGGSLQASPQLAPALTHLGHSLGFLGRALAAPARRRAARAAARAAADALFDGVLLRNRFAEPGAAQLGVDVGALEGVLEREGGQGVGAAGLRRVREGVGVLRAVGVRGRDGGGRERGERLGVLEEGDLWEMERRLFRDNVSARELLEEMGVEALTVKEARRNYTVERVGSASGGDAHPQVPSQAPTKAKSLGAGYWVPVYTVPSCRLGGHQLTERAGGVGTGSFQPCGLAGVGTAERGRLGREPGTCELNIFGQPYAVRRWVRLRFDGGNSEEGGVGSLWFDCARWRVVMSTHFDGAPSACRSTYDRGWHVEARPRRRRPFWNAGGKAGKRSGGTADTHSWHVVRGSRYASHGLVLDSRYVRPAARRWAFTRQSSPSSGRRPSRWSRRMAVGAVAGDRAGGAAKDDGRRVDDWPSVALFRLPKPDLVRIPLVTQDLGGALGHAQRPDCSRPALPLPPPRLSFAWTKDGSWAPIDPSDASIEPTPRPGWLRSDEDEAEMETHTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7M1</accession>
    <name>A0A6A6P7M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7M1"/>
    <dbReference type="OrthoDB" id="5563539at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="591" mass="65202" checksum="441846D877ABB966" modified="2020-06-17" version="1">MAQVLPVQLPDGQAGFRSSLRKSSPSQSSFLVGSPPSCGSNKTVRYGGAEFHEQISTSLPSSTVSSPTASQVNLAKSSSFHSVPSVAPPTSPQDDEKDTNITFPMYDDAPAFSHSEDLEPPASPKTENSYTVPSSSDDETASESTSTPDTFPTAGDDTSIKPEPQRHVDYLSHDWKEEEIWSSWRHIVSKRRQYGQLSRLENASWRTWAKAKYKLKTVSPETLNWLKDYDVTWLYGPLQTPSTYALSEHRSEPTSNLSKNNSFINKKPILKKRSMSEVMLQRSISASSLVKQAAAAVQAQQDASNGRVPQRPPLGRTASDFVGRTASDFVATPAASSKPVSGETTDYFSSTSASTSGLQSPSEKRHIRFDDKVEQCIAVDVKEGDEDEDEEPWKAEEDDDSSSDDGVVMMKTSKKAKPLSRSNSRGSFSNEGKTIAMLPSTRLKYRTDSPDIPDDMYAPTSRWRGGKLSPSPSQETLRPSRPSTNFLLGEDDQDDEDGDGPDWQPSRPFPDRRDSVAVYQNRLRPSDPDGRDPRSEESESSGGLRRTESGMFMPYEDDEQLANAGIFGKVVDTVNTARDIAHVIWNVGWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P911</accession>
    <name>A0A6A6P911_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P911"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025686161" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9690" checksum="A4FA4703C776885C" modified="2020-06-17" version="1">MGCVGSCARCVCAVWFVGRTRGVRTVCLVGLGCVGRRRGGRRRQRRRRMAMRKGSMGVGGFKEEWYVVGEAPSRVLPARMTDAARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P914</accession>
    <name>A0A6A6P914_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">homocitrate synthase</fullName>
            <ecNumber evidence="5">2.3.3.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_164987</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58884"/>
            <dbReference type="EC" id="2.3.3.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:12930"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.14" evidence="5"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P914"/>
    <dbReference type="OrthoDB" id="2015253at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004410">
        <property type="term" value="F:homocitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07948">
        <property type="entry name" value="DRE_TIM_HCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000002">
        <property type="entry name" value="Homocitrate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000032">
        <property type="entry name" value="Homocitrate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02222">
        <property type="entry name" value="Homocitr_synth_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048253">
        <property type="entry name" value="DRE_TIM_HCS_fun_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011872">
        <property type="entry name" value="Homocitrate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02146">
        <property type="entry name" value="LysS_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="405" mass="44230" checksum="57D0BD9EF6D2D8D8" modified="2020-06-17" version="1">MLDEFGVDYIELTSPAASEQSRKDCEAICKLGLKAKILTHVRCHMDDAKLAVETGVDGVDVVIGTSSYLREHSHGKDMTYIKDTAIEVINFVKSKGVEIRFSSEDSFRSDLVDLLSIYSAVDKVGVNRVGIADTVGCASPRQVYDLVRTLRGVVSCDIECHFHNDTGCAIANAYCALEAGATHIDTSVIGIGERNGITPLGGLMARMIVADREYVKSKYRLEMLKEIEDCVASAVSVNIPFNNYVTGFCAFTHKAGIHAKAILNNPSTYEIINPADFGMKRYVHVASRLTGWNAIKNRIEQLGLTMTDEQVKLCTAKIKAMADVRPLAIDDADSIMRTFHFNLHSGSEKPLLPNLTEEEKAKFIQAEAELKQEVVGMAGNGIKRAAEAPVEEPVAAKKVRSEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P968</accession>
    <name>A0A6A6P968_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_162194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P968"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="24744" checksum="5EB4F1AF991AFE27" modified="2020-06-17" version="1">MLTLSHHGVSPCRCLGGTSWEKPSPNANPAVGCRKPRHGTRGRSWRRDGSWGTAAASSGSSEPRGEAGNCMRGTFSPQSTTTRGERRTGLLCWIPTARPGLYLRPLPPHSLPSRGTPAARSQAEAVGLPYIAAPAASPTCIFILVRNSSRRTRPDNALRGVWRELRFHFLPPLTPCLVLVAIFEAGGENPAASEGGVHKQRYPHNWQWGLKGPDPHRWDGLVTLCLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9P6</accession>
    <name>A0A6A6P9P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_169331</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the epsin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9P6"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF110">
        <property type="entry name" value="EPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="524" mass="58073" checksum="A476644B54C0D78D" modified="2020-06-17" version="1">MAEIAQLTYNSSTDFHQIMDMLDKRLNDKGKNWRHVLKSLKVLDYCLHEGSELVVTWARKNIYIVKTLREFQYVDEDGRDVGQNVRVSAKELTALILDEDRLRAERQDRKSWKSRVTGIEEFGPPHASGFGNEPQRHPQRRPKRQDEEDLEYRLAIEASKNEAEEDRKRREKNAAVSADDDDLAKAIKLSKEEEERRRKELEDNNAASLFDEPPQQPSIQQPTGYNQGYQQQGEVDWFGNLVNQQQQQPQNTGFFSQPTGLQGQQTGYQNGLGYSTFQQQQPQQPGYDQGFQQTPFIQPQQTAFSANNPYGQQSNGFGDLGHQQQPLQSQSTLQPGSHNPWSTPASQSVDNLKPQPTGSNNPFASSFPRPSSAKPPTLSTLQEQKTQSQFNNTAFNPPLSFASPQPSPPPQKEANPHHAHLNALLSSGEGQDTFGNVGNLRIPAQHTAPGTFVNSAGSGINRLAATQTGNNPFLNQQFTGAPPGQQDRIMPAQTGPAGGFGGGNPFGPHGQQNQSGQTGSLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA50</accession>
    <name>A0A6A6PA50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_131602</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA50"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23164">
        <property type="entry name" value="Prefoldin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="120" mass="13471" checksum="598CA2ADD362A43F" modified="2020-06-17" version="1">MSIPPETLQKLLQEIEQKAAFSQQQISIVKSQIAAKNRESRILQLTTSEVDALPDSTNVYEGVGKMFVLSPRKDVKKRLGAENEELKSDISALEKKLHYLETTYKNSQDGIQRLLRPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAE1</accession>
    <name>A0A6A6PAE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_333283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAE1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17288" checksum="A184E81529E57C19" modified="2020-06-17" version="1">MLPTTPPCKFLLHPIQDVVSGWTDRICEKAPKQQTYPNKTENHSHPNAALSDHTSNTFTLTNHTLHPPNLPAIFPSQLPLFPPTSGLMCGGPSIPASGYPNAWLFLLGGAPAPAPPLPSLLLRPSPPLLLSSLSRSLRRSLLLSLSGSLSRSAYRSRSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAX0</accession>
    <name>A0A6A6PAX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_138437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAX0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="164" mass="17900" checksum="B78EF968B1370D3D" modified="2020-06-17" version="1">MLCSIRAFCGLAVHLRGHRLTPQSMAGAQSYGSGDGERMNAWGQTRLLMAAIWVDLNPGSDTLRQSAGKTPRKGCPGRERDDERDFCFLLSSPSLRTSRSSICTLVPNASAASRQLGFALLFSLHDLPVLFFFFPFFFLLGAPGSLSFGCLAVRLSHNATVRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBD7</accession>
    <name>A0A6A6PBD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_259570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBD7"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="2">
        <location>
            <begin position="14"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="129" mass="14229" checksum="CF587C1A626DC8FC" modified="2020-06-17" version="1" fragment="single">PHLGSPAPAPTWSQRWRQLSREYGQSALGVYLVLSALDFPFCFLAVRMLGSDRIARWEQAVVGGVRGALGKVLPAYDTADGRECSNTCPALRTAIWTQLALAYAVHKSFIFIRLPVTVMVTPKVVKTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBL7</accession>
    <name>A0A6A6PBL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AHC1-like C2H2 zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_383422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBL7"/>
    <dbReference type="OrthoDB" id="5355528at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058706">
        <property type="entry name" value="zf-C2H2_AHC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25909">
        <property type="entry name" value="zf-C2H2_AHC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHC1-like C2H2 zinc-finger" evidence="2">
        <location>
            <begin position="305"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="636" mass="67504" checksum="871FAA76163A067D" modified="2020-06-17" version="1">MQSMFRFPWASEPGGDKHLMDKFAQPQQSPVVDIPLLNKLKRKATGSPEPVSPQAGFVAKKWKCGSEAQAPNAPTRRSVKADVDVLSPRPSRKSNAPEDVAQGVAAKSPENSSPVFPSTVASSPMQDTVVSEVYTPLQEAIEAHFNYEILLKHQELRLIEQELAKCQISLEQLRRCQLIPFPGSESASENVSGGVGPALEPPSGQHRPQHPAPWGVTDGPYTRHYAKWLIPDPAFDSVPPYDLGAAHGLTQSTSGRSTRASYLDQAGVAGKSRSSRNSSNAKLHALTSDVAPPKDKSGGPLYLRRSTDGQLVELFCDACQRGDFSSVQGFLNHCRIKHNKEYKSHDAAAIACGRPVDEETSASAAPGPQSVAPTSAPVMTPATEHPPALPSLAGGASMVHPLIRSNNTQQTNKLPPRPLKGANTLAPKRQKSPDPVADATSNRFVASAKVPHLSKLISKHGFDGCFDDFVGQASAKIDIGALEGPSDDEGDSALTTPARETPTVKSQQQLSRLPARAPAPLNSSKIPRAKMTGGAQPQRQQQPGSLNVGSKHVGLESPTVELSPNTVESNPGLVSDREGDDDDDDEARSVAPANLGAEADIGVDVEVEDSSDVERPSRVKGLRGFGPGSSRKGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBQ2</accession>
    <name>A0A6A6PBQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glucanase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_278349</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="11">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBQ2"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.40:FF:000001">
        <property type="entry name" value="Glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF2">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025708675" description="Glucanase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 10">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="392" mass="42230" checksum="06EB3DC8A9005D3C" modified="2020-06-17" version="1">MKSVIYAATAAAAFTGALAAPSTPKSKRQMGADCSAVSLSGNAFAQYEGYANSYYAAEVEAAVEQISDPDLAAAAARVADIPTFMWLDTRAKIDILEPELQMVPCDEIIGLVIYDLPGRDCAAKASNGELSYDQIDVYRSEYIDPIAEIISRYPGIPMALVIEPDSLPNLVTNADLQTCQDSASAYREGVAYALEQLNFDNVVMYLDAGHGGWLGWDDNLEPGAQEIADAYQRAGSPSQVMGVASNVAGWNAFSMNPGEFANADDAQWNSAQDEQRYAELFSPLLEQNGMPGQFIVDTGRNAVQGLRDEWGDWCNVDGAGFGVRPTSDTGDSNVDAFVWVKPGGESDGTSDTSADRYDSYCGKPDAFKPSPEAGTWNQEYFEMLVRNADPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBX5</accession>
    <name>A0A6A6PBX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_360548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBX5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025497888" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="18456" checksum="6DBAD5ADE081B7E5" modified="2020-06-17" version="1">MPGWPPCCCSSPLLCSAAVICTVHCSDRSNRDPEAQPARPPPGGWPQAKSKGPDRQNNPPFPSEGRHRQKNHVPHLIPVPGWGGSARERRPSPGARASPPLPGTPTTAAGGRSRRWVFWPAAVKDNDRVRYGAYGQARKRKVVFAAYATLNLVGRQCVFRGAIAERHDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCA2</accession>
    <name>A0A6A6PCA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_332046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCA2"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000054">
        <property type="entry name" value="DCR2p Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="216"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="543" mass="61048" checksum="3B2C628C2D075DC8" modified="2020-06-17" version="1">MTRRIVRTIIQLGLFGFCSFLFLYMLDNQYGVLPTSIHSHLPAHHPGLIIADVHLQYCNLLNPLTSCKLDPSKWHRIEKDLYLNSGLVQKAYLHIKRKKEEELTAEDKVVLDVKIGRLDPAMGEKGEDNEKWESRGSGIWLKRSAKRHDSDSNNVITAIDILFGADAVEPRPGWEIKDTPLLLSSDGVPEARISVRRGSPKKVEKPIPRIRKDGKFKIMQVADLHLSTGLGACRDPEPKEHNGGKCDADPRTLEFVERLLDDEKPDLVVLTGDQVNGDTAKDAQTAIYKYAHVFIERNIPYAGIFGNHDDEGSLSRQGQMALIESLPYSLSEAGPNTIEGVGNYYVEVLAHGTSAHSALTLYLLDTHAYSPNEAQFKGYDWLKPDQIEWFQNTVRELRTVHKHYTKIHLDMAFIHIPLPEYTEPAEIFGNRKEGVTAPGFNTHFKDALVEASVPIVTCGHDHVNDYCALAKTDEGQPELWMCYGGGAGFGGYGGYNGYVRRIRLFEIDTNEARIRTWKRLEYGDTETRLDEQVIVEAGRPFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCH5</accession>
    <name>A0A6A6PCH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_314113</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Cytoplasmic vesicle</location>
            <location evidence="1 16">COPII-coated vesicle membrane</location>
            <topology evidence="1 16">Peripheral membrane protein</topology>
            <orientation evidence="1 16">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Endoplasmic reticulum membrane</location>
            <topology evidence="2 16">Peripheral membrane protein</topology>
            <orientation evidence="2 16">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Golgi apparatus membrane</location>
            <topology evidence="16">Peripheral membrane protein</topology>
            <orientation evidence="16">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCH5"/>
    <dbReference type="OrthoDB" id="10256289at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01478">
        <property type="entry name" value="Sec23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.730:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000006">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000008">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 16" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="8 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 16" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12 16" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0813">Transport</keyword>
    <keyword evidence="9 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="18">
        <location>
            <begin position="60"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="19">
        <location>
            <begin position="127"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="21">
        <location>
            <begin position="406"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="20">
        <location>
            <begin position="524"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="17">
        <location>
            <begin position="640"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2461539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="773" mass="86372" checksum="861E78C0B1F536E9" modified="2020-06-17" version="1">MDYEALKEQWSEIEDRDGVRLSWNTFPSSRMEASRLVVPIGALYTPLKEKTDTPLLQYEPVSCKAPCRAVLNPFCQVDTRARLWICPFCLQRNALPPHYKDISQDAIPPELHPNSTTIEYRLARPAPSPPIFVFVVDTCQEEDSLKALKDSIIMSLSLLPPYALVGLITFGTMAQVHELGYTECAKSYVFRGSKEYTAKQVQEMLGLMAPGLRPNMMQPQPGRAPPPMGPAARFLLPVQQCEFQLTNALEQLQKDPWPVANDKRSLRCTGVALSVAIGLLETSFQNSGARIMLFTGGPATEGPGMVVGPELREPIRSHHDIDRDNIKYYKKALKFYDNLAKRTAHNGHIIDIFAGCLDQVGLLEMKGLSNNTGGHMILTDSFTSSMYRQSFARVFDKDGDDNLLMGFNASLEVITTKELKVTGLIGHAVSMNKKSASVGETECGIGNTCSWKMCGIDPSASYGVYFEIASQGGPTQIQQGPQKGMMQFLTYYQHSAGQYHLRVTTVARNLSGPSGDPAIAQSFDQEASAVLMSRIAVFKAEVDDGPDVLRWVDRMLIRLCSRFAEYRKDDPSSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNHEDVSNSLIMIQPTLDSYGFDHEGSQPVLLDSTSIQPETILLLDTFFHILIFHGETMAEWRKAGYQDQEGYENFRALLEQPKEDAKELIQDRFPLPRFIVCDAGGSQARFLLSKLNPSTTHTSGTYGGVSQTAQTIFTDDVSLQTFMDHLMKLAVSGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCU1</accession>
    <name>A0A6A6PCU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_91111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCU1"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000024">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="200" mass="21800" checksum="BD1D501FB3C0E990" modified="2020-06-17" version="1">MTTRLVLCLGDLFIPDRAPDIPAKFKKLLAPGKIGQILCLGNLTDKDTYDFLRGVAPDLQMVRGDFDVEAANLAVSKVVTHGSLRIGFTHGHTILPPGDADSLLIAARQMDVDILLWGGTHRFEAYEMEGKFFVNPGSATGAMTTGWWTEDEEPTPSFVLMDVQGDVLVLYVYQLRKDASGAETVGVERVSFRKNGGDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCU8</accession>
    <name>A0A6A6PCU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_260398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCU8"/>
    <dbReference type="OrthoDB" id="3939017at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="740"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="838"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="883"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="851"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="889"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="901"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="920"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1042" mass="113761" checksum="029AF75F54A4BC89" modified="2020-06-17" version="1" fragment="single">RQKSTSKKDRPGLPKRSSSVRRAYHRIFGGGDSQDASPETKGVEVYSSDLERIQQELKRCEQALEEANNMIVSQLDEISELQRYKDRIDVDFKLKEQALMQQTAAVEEHMVAVVVQQIRDARASEREIVRQEMERQNRNALENLRRRHEEQILALSAPRTVTTEGEEGQSALQPNHELDLLRSEIAKLTAEFNVAKAEAAENSAQLAELRQAAELEEHEAAKAELEAAQAKIAELTTATEGVESLKAELEAQRSLKGDLEASQARVTELSAASESLSSVKAELEVALAQVGKLTEDLETHNAVKADLEAKLEKLTAEIDGQESLKAELEASKDQIEQLTKDVEATASVKSDLEAAQAQIAQLTQEIESFASTKTDLENAQTQLEELTSKLESHEATAKNLEDAKAQVTQLTQDLESHASLKEELETSRAQLEKLTSDAEAHTTTAQDLEAAKAQVAKLTEEIEGHAATKSDLEEARAQVEKLTVELEGHANTQISQLTADLEGHSAVKGDLEKAEVRIAELVKDAETYSSTKSELEAALAKITTLEGDLEESATIQTQLESTKAQLVQATEELEAANSAKEELQKAQARIEELTKDAEALASTKTELDSAQEKLVELNEKIEGHAATEKEVETLQAKVAELSAAADAHETVKTDLETERAKVAELTTIAEAHESAKADLETERAKVVELAAAAEAHESTKADLDTAQAKIAELTKDIETGQADHASITERLTAAETALKAAEENHTATASTLAEKQQELSEARSDHESAKEKLTSLETELQDAKSALEKAEATSAAHGELQSQHETLKEKLLTLETDLQKSQDALKDQIASLEEAKTRAEEALKAANEAKVAAEEQATKDEGELTAAKDSYAELEAKLAEAMTAKQMAEESLASASQESQTLKEDLEKRLATAENSVSELEAKRKADTEAADSAKGEFEEKIKAAEGAKEATESRLKELEESAEADRTAHEKASSELKEKEEQLKEALAKEEEARSQLEAAIKEKEAEVEKVKSHEGDFKRLDSEKAGLEEKLEALQEAHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDJ2</accession>
    <name>A0A6A6PDJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Homoserine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_389037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDJ2"/>
    <dbReference type="OrthoDB" id="9972683at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005757">
        <property type="entry name" value="PRK07581.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF15">
        <property type="entry name" value="HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="60"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="357" mass="39473" checksum="6BB32B188D17C7B2" modified="2020-06-17" version="1">MKEEYSTYKLGDFKLKSGGVIPDAFIAYRTFGDPSFPAIIYPSWYSGSLSDNYWLIGDDKTLSPQKYFIIVTALFGNGQSSSPSNTPSLKPFPDVLFYDNVAAQHRLVTERLGVTHAFAVLGWSMGAGQTYQWATQFPDFVDVIAPFCGSAKTSLHNQVFLEGVKSALLAAKGASSAGSAKGEATLGSEYRSWTEEEKVAGLKALGRVYAGWGFSQAFYRERLYEKALGFKDLEDFMVNFWEAWSTSKDPENMLVMLQTWQAGDISNQEPYNGDFEKALRSIKAKALVLPGKTDLYFPPEDSAYEVENMASGMGKMIPFPSIWGHWAGGPGQSVQDVKWLDEKLKVLFESGLDAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE06</accession>
    <name>A0A6A6PE06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_9098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE06"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="16927" checksum="5CB7332E2C3E3CD3" modified="2020-06-17" version="1">MGDASPCASEKRALPSSRLPPAAASSFPLPSRSLPASSTPRRLPSASCCTEAVSHARRRSSSSVRSFFTLVSNAPPTLEALSPFRSLPSSCFAVNKRPTLPSPDSRSRARSPTLTPAHETLSRQVLAHSPLQHLGLPLHVGNISCRSLYRFSGFNGGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE24</accession>
    <name>A0A6A6PE24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA ligase</fullName>
            <ecNumber evidence="16">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_383129</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="16"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE24"/>
    <dbReference type="OrthoDB" id="151490at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000234">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000013">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3260.10:FF:000008">
        <property type="entry name" value="DNA ligase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044125">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021536">
        <property type="entry name" value="DNA_ligase_IV_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11411">
        <property type="entry name" value="DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="19">
        <location>
            <begin position="447"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="20">
        <location>
            <begin position="746"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="20">
        <location>
            <begin position="955"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="711"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2462080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1031" mass="116131" checksum="7D87C9621DF3FE33" modified="2020-06-17" version="1">MAADVTMQSAEAAEEEEMQYGHGNISIEELGEKFPNRPHNHSRTLPFSSLFLTLFNPLNDNKKKPTATQPPLSRKKRGPHGPTAPTPYENRRNIIQRFIARWRSNVGNDIYPAFRLIVPEKDRDRPMYGLKEKTIGKLLVRVLRIDKDSADGRALANWKLPGRLGTAGGRYVPGGSAGDFGARCFEVVGKRAMRTEPGDLTIGEVNAMLDRLAAAAKEEEQLPVFEEFYRRMNAEEIMWLVRMILRQMKIGASERTLFQLWHPDAESLFSVSSSLRRVCWELYDPAVRLDGEDRGIKLMQCFQPQLAAFQMHSLDKMVGRMLRTATEEDDEFWIEEKLDGERMQLHMVEEDSAPGGFRLGFWSRKAKDYTYLYGSSFEDESSALARHIRPAFSAGVRNLILDGEMITWDVDQGCVAPFGTLKTAALAEKQSSNVFDDNTGQRPVYRVFDCLYLNDTPLTQFTLRDRRAALAASVSDIHRRIEVHPYTVGQTAADIETALRRVVAESSEGLVVKSPRSAYILNARTDDWIKVKPEYMTAFGEALDCVVVGGYYGSGHRGGTLSSFLCGLRVKDGSEKCFSFFKVGGGLKAADYAAVRARTDAKWKTWDPKRPPSEFVELGGGAAQLERPDVWIRPSDSVVLEVKAASVAQSDSFRAGLTLRFPRFKRLRDDKSWEQALSVDEFIQLKEGAEREGREKEFEVDTWRKRKNERRTRKRPLVIAGEEGAGDEPAASGKRVAEATAAEDPEVGDIFKGLTFHVLSDAVTPKKMSKDGLETFIKAHGGRIVARPADQDTVCIADRRLPKVVALMQTDRHTLVRPAWLFDCVAQAAADARRSAPTGTPPPRLLLPWEPVRHLFFVKSAERFDPAANVDVYGDSYARDVDVDELMEIFRHMPKAEDGDELAAEALRALEEEGIRLEEIKTWLFKGCVVWFAYGDEAEAEEGEERRRVRRANWEVDLAETTVKFAGGKVVRDVSLEGVTHVVFGRERGLLDEVKRALDGLKRPHIVSLDWVTESWKEGTLIDEDRFTIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEN3</accession>
    <name>A0A6A6PEN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ARS binding protein 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_331448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEN3"/>
    <dbReference type="OrthoDB" id="2104370at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018562">
        <property type="entry name" value="ARS-binding_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42048">
        <property type="entry name" value="ARS-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42048:SF1">
        <property type="entry name" value="ARS-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09441">
        <property type="entry name" value="Abp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="845"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="619"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="696"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="746"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="765"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1104" mass="115429" checksum="A55D2215F42F7749" modified="2020-06-17" version="1">MDSASAAALDSAAAQVAAARHHHGQHHAHSHSGGGGASFHHRHQNPQSPSPHHNHHNQHMLHDGSSGAGGGTGSGGLAPQHFYGPASAAPDTMSRSSLPPSTPSTHAASPRFGSGGGGAKASTGHAAAASASPPPTGGSGGGGATAGGAGGAQQQQARAQTPQAHGAPGGSGGANSNGRPMLMPGFVPQDRSLPARSDALSGADALGRAYAAFILYCNPTFGPSTDTAELVQAFSAPPKSDGKSFSTWSLWELIERLERKDIKTWTQLALELGVEPPALDKGQSAQKVQQYSVRLKRWMHAMHIDAFFEYLLGKQHGYYMQIPPPENPFPESGRDGVPLEEDLAIRNLDPRFRPKRGRRKAEEVEDDIDHQATPPPKRPHLDTSMAFTSPNGFGNPHSAFPASALGDDFASTGDPWTAVTSVNSALTPHPSKSLSTTSAIHPQQLRWRLNVGGDSANPMTPHPLSAITPASATTDATFDEVPQSAITPSGRRARRRHGPAVSSAWPSSSSTPNGKLRGRPPSNRSVRDGPFVTFPANPKTKEAPTIELGGKDGTGNSGNGGRSSATPGPMPVVERAPSEPPLPRQQLSPAQRHHAIPASAHPSSSGPRQFPARPPHSSPHPSSLAPSAVSQPPLPPPPSQGRPERLQLQVPQHVGGPVHLITPTVLVNGQSNEDPNGPPPAPLSLALSGNGGGGSRRSSAAGPGADAFFDDDDDAAGAEDIPDSTNSFGMGPTRLGTPGEQPRPQPQHTRLSYSPATTVGVGTGARSSTPQQNSSHYHLLQQPANNGASNLRVPPPPPPMSTIFHASPSSTANANLTTSAPFPVRSFADLQRALATDLLRAEVSGRRPVRRRRGASSSASKARPPRLKGAEAKVLAAAMLRRLRGQPSHLYRSAPLDADTAENAAWRVACAAWLGLALVGSEAQTPAAANGGQPWLPTPWPVGAPKRIDVRLFRVTDGFYHLIEEDEDEFDGRGNAAGGIVQECFDISWSLVLGAGSAEAEFSVKGLDLDNDVEAEEAGAETNVAVAAAVREDAEQGIIDSEEEAAAAGAAFDLSEEGVGLLEGGTRASEAVEWRARYLAIRQDLREKEREIHRLKERVLEAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEP7</accession>
    <name>A0A6A6PEP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_2769</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEP7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="20454" checksum="4F16E95F7ABE6AD9" modified="2020-06-17" version="1">MLVCAPFRRAPRLHAGNRLSAHEHMGNPRRSSRRLALVAYPATLCSDDSADAILEGCGPPLLLLRLLRRSRAGLPALESAAARAVLASRRPRIGARTLLAAVVGTKLVEIRVGMNAVAIRSSTTLAVLALFPPAFLRLLDRSDHGTEVTCVLGKVAELLLKLACECSMCSPKCRSRLGTGWRGSAAGPLLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEV1</accession>
    <name>A0A6A6PEV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_277440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEV1"/>
    <dbReference type="OrthoDB" id="4818801at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050278">
        <property type="term" value="F:sedoheptulose-bisphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046390">
        <property type="term" value="P:ribose phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF15">
        <property type="entry name" value="SEDOHEPTULOSE 1,7-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="28"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="103"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="234" mass="26279" checksum="FAEB831200BAFD33" modified="2020-06-17" version="1">MADKDSATPRVFLFRHGETEWTKSGQYTGRTDISLTPHGAKQVKATGRMVVGRGKLIDPDKLGLVFCSPRIRAQTTFKLAVGDDEVHKLSAAGKVDITEKIAEWNYGAYEGLLTHEIRMLRAAHGLDSDRPWDIWRDGCEEGESAKDVTQRLDDLISRIHELQKDNMHGEKNCDVALFAHGHILRAFVKRWLKYPLEFRLSMMLEPGGVGVLSYQHQNVEEPAVLVGIGFPLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF20</accession>
    <name>A0A6A6PF20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_389965</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF20"/>
    <dbReference type="OrthoDB" id="261831at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000057">
        <property type="entry name" value="SNARE complex subunit (Bet1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="32"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2462319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="122" mass="13038" checksum="7DE092D87C41B941" modified="2020-06-17" version="1" fragment="single">GAGGAAGGGGGAGGFRPATPNARGQYSDAVLSELESQNEEHLGGMIAKVKALKGVSLAIGNEIRDSTALAEKMNDSFDSTRVRLRGTMNRMLRMAERTGVGWKAWLAFFAAVVLLFWYVWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFV1</accession>
    <name>A0A6A6PFV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_10636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFV1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="13033" checksum="8E5CC972846DD82F" modified="2020-06-17" version="1">MQKVLACDASKSLDQGHTSSAKKGLLHLLSIPPCLHGFGAVLLPLSECIFHEAFHHLPSEEIEIIMMESQTWRFLAALASVPSAPTLLDLQHHGRQRWHQPADDVLGRLVDDLSHSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLB8</accession>
    <name>A0A6A6NLB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_375560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLB8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025374222" evidence="2">
        <location>
            <begin position="21"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="233" mass="22364" checksum="3AE2421801D1F785" modified="2020-06-17" version="1">MRVTSTFTLFAAAAAGLAAAQDPANFNEDTMPLAYRSMSASSAAAASTSAPSNAPLAPVEDVGEIVSDVVSSVADTVPTPVTTSDGIFSALPINATSLSLTTPSSLLPLPSSLNRTLTAGVGTGTGTGAGTGVFPTGTRNDTLASGTGTASGRANGTTSTISTRARSTVTSVTVIDGEAPTQSGGGGQSGGADSQGAVETGTSSGGAEGGVFRHRESGGVAALVVALAGLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLG2</accession>
    <name>A0A6A6NLG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_158965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLG2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="923" mass="100978" checksum="C9F1EA7C76F35B2C" modified="2020-06-17" version="1">MPLEGWDPEMSRAEAADLIYDIFDIKDYGRRRFREIIRAMSGKRYRGLFDQMCDGERALFDAEAMEYRRQISTGKQSKARKREKTDEVENDIKETPEKRAQSSLIETEKQRTVSSTTKDEAISPPRRNKARSKIQQSGDSPIVSAAHVSTADETRRATLGAKKELSRPVVKQEHTSTSANKQAHPEPTPIKRKRGRPKKDHSVAPKTPVRPIATGTQTELDEFNEISQKLRDKVQDISKNLVGDSSDSWSLLFSEQAVDKATCIVRKRKAEANISTLWEEYGASSGMGKEEFSAMVEHAPLEELDTLLNPQKNDGIGQSSERPRKRVRIVSESPQKSTSGSTPTLLNRMGTAHTSADRQDLANDDAQPSAISDSTSNSSSDSTSDSASNSTSASTSKKEAETTVSSSSTTNTTNSTSAMSGVLHNFNRVSSASTSKESEDVSDQESDSSASGDDEGESKSSSLVYNESTEADDVPKLFLGATASDPALDSVKNYRQTHPFFMHASLEDTPDELAGYLADVAQYAQDIGVDKAGVQKCVEEARAAHETIQEWLLYQSGPLPVRDGFSSSPDPDMTLEDLVTAPREASPRVETPKCSTPVSSSRHSDLPNRTPEPSEQTRVIPESPQPMIPEEKENEVREGLWVMNDIETRDSPDDGQELLPEEDPEGSQFTPMEVVEDSADEGAVVDDEESMSTDESHSQLGQAVGEEFPTEQEVPAASDITTAEGVLQVQPSGENVGMESPEIGSKELLEQEIGALENEADDQHEEERPDEDGSVDTTSNQESGTPSRESEISARKQDEQPEDIAIDEAVSASATPKTRSIADTQSETSETAPVRPWFSSKDFGETGDTIISGNWAYPESSAEKAVDSTMQEGFRNPMIRQASPAMRMGISPKILMEGNSPSRNLLQRTAMLASSLIYVLPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLS4</accession>
    <name>A0A6A6NLS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_358734</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLS4"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27225" checksum="8C9C3EF7090C67E0" modified="2020-06-17" version="1">MSYNKPHLSPLSPISPRSLPFLLTSTLIFIPTAVLLRHHVSHHGPFRVAPTIIKLNSRLYSLFSLLLFLALLPPPVSPLPAFDDSTLRYAYHVSKLYEYVDVFNVLAAGGSIGAHFGFHHLTTPYLTYVRTLNHAEPRGWRVVAMLNAAHHAIMYAYFGGVWSAKWLRMVLPWTGFAQLAVGIVGELYIILGSGSAGNENEEVWRNMVSLGLLACYFVLFVMEMTALRKNKDADSEKRDGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM31</accession>
    <name>A0A6A6NM31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_358009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM31"/>
    <dbReference type="OrthoDB" id="10253329at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="46546" checksum="125235CACD173339" modified="2020-06-17" version="1">MYDLEPCRVEIVGVEGPGGVEAREGVERAFAARAEDRRDLSLVNHVNWLAQNMHALVVQEGGGGAQARARVDGPGAVEPGAEPGAIVLEKDGGEPAAKEEKEARDEYYYATDLPSRSHIIKIPRPPEWSAGDDDGGDDSSDLTDSYSEDDDEAEEQEDDAQRQNQTSMTSLAERGIMISLPFLELHGIELLELVSPSVTVKCDRCKTTMDVSSLKNNTSASSSGMRTESCKKCANPFGIGYRMDMMHANSVRAGYLDLDGCTVVDLLPSAFVPTCSECSTPASSVAAVRGDAAMAICRECHRRMNFHIPEVKFLLVNTSTGGAKEKLGIVAGHELPKRGRCAHYSKSYRWFRCHDETESHPNEHANRMICSSREQNYRPEDCAICHATLVGKRGTGFWEGGKGKAGLDWLRLFFSCHSEFFLTAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM67</accession>
    <name>A0A6A6NM67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_328628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM67"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="117"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="360" mass="39737" checksum="F75FE9E5C7A835B4" modified="2020-06-17" version="1">MSEAPGKGSLSVTEKVMMALKLGTVVPWLFYQAAAAIFRDKETTRSWMHEMRNRFAHHCLTCFSVDELPYTPLFPSTESVVAGSCRKLKWPREIQDIPGGEGARIHWLGDQKAKHVLLWFHGGGFALPANPGHTNFLAECQKKLDAAGKNVLVALVEYTLTPYAKFPTQPKQCLLAYKEALGRGYGAENIIIGGDSAGGNLAVSLLLSLHHHPPSLPQVSSQGIVAGLCLVSPWISYSGQSESFKRFNDYDIVLRDQVLDWADRYQPSPLRDIYSEPARAGPDDWKDLPVKKVLLLASTGEVLHDDIIEMGQKMEKGGLPMTVVQCPKSRHIECIQDAQVGLTPGTMSEAVWEWLPTVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM81</accession>
    <name>A0A6A6NM81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM81"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="16981" checksum="D69CF0C14C6D7014" modified="2020-06-17" version="1">MLGSGALGLAGRGLGCPVERIWRPIRPRRTDDERDGGPGPVSCRTQASRTTWDVLFSCKEWRRSRAIRRCCTGVLCSSREREPPAAPCSNLMRLRIPIGCPFQHGPGSSVLATYAWTKAAFLTDCLGTRSCKASRGTSKTRPGHNPGKHDISPAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM95</accession>
    <name>A0A6A6NM95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_358312</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS36 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM95"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000165">
        <property type="entry name" value="Vacuolar protein sorting protein (Vps36)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000527">
        <property type="entry name" value="Vacuolar protein sorting protein (Vps36), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021648">
        <property type="entry name" value="GLUE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031558">
        <property type="entry name" value="Vps36-NZF-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16988">
        <property type="entry name" value="Vps36-NZF-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11605">
        <property type="entry name" value="Vps36_ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51495">
        <property type="entry name" value="GLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GLUE N-terminal" evidence="11">
        <location>
            <begin position="6"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="322"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="619" mass="66843" checksum="BA75B42D72A7D7E3" modified="2020-06-17" version="1">MFLRHLDLTTALRPSLLPDETLLFVQDAVGLYEGKYKIPSYQNGHAYLTSHRACYVDNEEPRKHAVAIDLKDVDRPEFYAGFLKSSAKVTLYPKASKRSSLSSRAPVVNPQISPSPTPPARHGSPLRSVTPSPAPPPPASATWICPICSFSNPVPSNFDPSTANANTPLPPCLACGIKPPLVHVAKAAIAALTSRQAAPGTIAPQNEGVSSQVSEATRQGRGAEVRPSFQCPRCTFENHPSLLTCEMCGASLISAVDRRLETIGGPNVRRAESPGPSLGNLSLEDDGKECIKFSFRAGGGAVFFERLKNALVQRKWLLQSAPPVPTPQLSSSTTDEGGLAVAAGSDSSQGGQRKVVGIAGLERRGHELRKNNEIVIGNAFEDLEALMTSAKEVIALAEQFSAQAGVANDNGNPEASALLSQSASALGLVTTKDMLGSGSGSDSLYISELSRNLAEFLTDDAKGVLKREGGIMSLVDLWAVFNRARGGVELVSPADFAKAAELWDKLKLPVRLRRFRSGLLVVQGRERTDERTIASLLAWLRELHDQPPEEECSWDWRRYGRGVTTQEAAERFGWSVGVATEELEMAEERGALCREQRLDGLRFWENWLVWGNGSSGGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMB7</accession>
    <name>A0A6A6NMB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_149476</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMB7"/>
    <dbReference type="OrthoDB" id="2264563at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13311">
        <property type="entry name" value="PH_Slm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046868">
        <property type="entry name" value="BAR_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046869">
        <property type="entry name" value="SLM1/RGC1-like_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043453">
        <property type="entry name" value="Slm1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941:SF1">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20400">
        <property type="entry name" value="BAR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20399">
        <property type="entry name" value="PH_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="298"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="509" mass="55296" checksum="88A3CAA54FD589B8" modified="2020-06-17" version="1">MSSPTESLPRRTTTMGTDDDAVPGEDTSEVTKLMLERLQAFKHAVGYIEDYITATEKAHNSHGKEYERVLKTVSHPLKEGHHFDQQLGGIAGMFDNIRSNTQGIANSHHETAKTLKGSVLPMFERLHAEIKNKSKELNKGAGKQSKTVDKARNTTQKHIELLGQHTATFDSTGGKMSAADDPYVLQRGVYHRLNKQVVEENNNRQDLLSVQDSLKKFEAHVIEVIQQGLGSFNQVVSGQAEQTRAMYGNIVATAHAIPPDFEWKGFIARNEGVLINPDNPPRTVSSISFPNQDHRATQPVIAGALERKSKMLRRYETAYYALTPAKYLHEFKTDDDFGREPTPELSLYLPDCVVGAIDGTKFHIKGKDVSKGKVGNTFSMSHELQFKAHTPSDAQQWWDAIRAAAGQVTAEQPPPSEPTSPEVARKESQPTSTDGSPAPAAAAAETPSAEKKEPTEPAEPANASTAQSPTNGEASGTGEASGSGGASGPPPSWSAQGEAKKEEEKKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMD4</accession>
    <name>A0A6A6NMD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_357848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMD4"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="41"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="385" mass="41529" checksum="E68E5133C72ECFE4" modified="2020-06-17" version="1">MSDTDRAPPFLSVSSDNHAPWVVVASCILIVLSGLTVAAKIIFRLKSAKPSLYDAFLAAATLVAVAETVCVVLACGHGLGKHRSHIDDADFELVNKFYCTGSILAVASLALSKTSILQFIVALNPQQNVVDSCYGTLAIVVVWAASSLLALALQFEPTLHVDQRALYVYIGVVNILTDVALIAIPTHLMFLIRKISARLEIIAYFAVRIVVPVFTIIYLVSLSSRFPSEDPTWDAVIPTIWHQVMLNLSIITACIPSLKRVLDAFRSGAAAASISTPYQLTVSKQSSLGRLRLRAKGREDPSSRGNSSADGNRERRQHGRSSHISASDSERTIPTNSGWKVTKTAGLAEDVPEIHPEVELDGRSQGDVSETTGPLGDEQSGHVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMJ2</accession>
    <name>A0A6A6NMJ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_329029</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMJ2"/>
    <dbReference type="OrthoDB" id="5584477at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="403"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="507"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="769" mass="85997" checksum="BFDD4DC04BE6D011" modified="2020-06-17" version="1">MTQFSEDQLQVIKTYPIKDELDSFRASFESACAPINDRSDNVEEFLVSFNGRDIVLNLLGALQLLPASSRLCFGHDVGRLSGNIALLYAGLSSGQIDLRHTADLVRAVVARAEDTQIWTAVYDLITRTKPSPVTPPHSGAPFAVSKQTPWKFSTASAVNSSDLRRDVGPMLRAEMENNITIDQPLLFDAFFGQVSRLTEITAAVFKKCKATEPPLYTDDSGWTEWPGSCEESKVLGWLRCLISQMLTFANESGFRPSKRRRYIATPNKPLLGSVSKRKLDVGLAYDPGNQVEGYDNQDCAWTDILIAGELKSNPQEDTHNSTWFDLLRYVREVFGAQVTRRFVLGFTLCGSIIRLWELDRLGALASRPFDINRDGQKFASMILGFLWMNEEELGFDPTIVEGGKQVEIQRDGQYERLYLQDVIRRQRSVVGRATTCWIGRLIGTKPMQRVVVKDSWEYEERPEEGDLLMNATKSGAENVALWYHHETVYVGGTVDDVYHNVRKGLSTADAASNSSGPGNGRSASGSSMRKRSRSSLQISMPPPKRSCSGSQRLRNRVHRRVIMHGVGKSIDQASTLKTMLTALLGGIKGHESLLNINILHRDISIGNIMLNEAEDDGFLIDLDLAIKANREEVSGAPSKTGTKVFMAIGVLHGDEGHNFMHDLESFFWVLFWIGVHWNGPGQSRGNSKYEAWNYEPTTQLAQIKKGTVVEEDSFSKEVGESFTEYCKPLVPCILELRKVVFPGGKRWLSEHRGLYPRMKAVLEEAREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMM3</accession>
    <name>A0A6A6NMM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic membrane protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_293952</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMM3"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="712"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="228"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="838" mass="90966" checksum="9C94C21E91D92D87" modified="2020-06-17" version="1">MRRKHSATGRRDTVPAHDRGATIGSGSVDAQQHERQRRSSGLRHIPAPLELVGGRLADGHAGKSKDSSSGVPSASATAPAEPAKPLPPPGPGASGHLPQLSPMPPSLPLPPTSIPTYLQLELSAERPSPLYIHRPSSPSYDSPYESSAVKFERLVNFLFLPPRLEGVLWFGALACLDAWLYTFTILPLRFGRAVGLWARWWARNAWKESMDLGGFVWAGVGRVWRRQRQRRRSSSVQQQQHRRGSAIASGIEAVSPLPPTTPLLTPGRAPLSRQNGGTTPLSATHAFPTSNGTVVGESQRKHSKSNVFRHRRTKSTPSSLRPNHKADILKGLLVIASCAVLMKFDASKIYHNIRGQAAIKLYVIYNVLEVCDRLFSALGQDVLECLLCRETLERGADGRSKVLRPLWMFLLALVYNVAHATSLFYQVITLNVAVNSYSNALLTLLMSNQFVEIKGTVFKKFEKENLFQLTCADVVERFQLWLMLLIIALRNIVEVGGLSLGGGRSSSFLSSASPPPPAAGGVNGTSVPLRSSTTILPLSFTILPPWTGQVLTPFLLVLGSEMFVDWLKHAYITKFNNVRPAIYSRFLDLLARDYYVHAFSADAGAGAPHGLTRRLGLPVLPLSCLFIRSSIQTYRMFLATHMPGPLSSSSATSLSVPGPTGTSPATTAALAQLDMLIRRALGRSASFGAGTAATAAAQGSTWWARWYTVDDAIALVAMVLVFGCLFCVLLAAKLVLGMALLAWARGRYGQMKEREAALGAGAAAAPAVVLEARRVGGWGVVEVDEDKRRWIYADAPEEGRALRDKEERARQRAAGGAGMEAVELGGVSRYAMVAKRIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN78</accession>
    <name>A0A6A6NN78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_143126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN78"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="16359" checksum="B6079B4EBE019E16" modified="2020-06-17" version="1">MMPGCAPLSIESRVPVLRQAGATTGRAVAGQHSHRGLFQLRVAMGRSGGSIWRCGNQRSLGSLPGPLQPILGRETNTPVSAPLVGCAALRFMRGEPGCRGILIGSGAKISDPRGCNADELRSSREKSANEEQVSEPARWHKNLRKLSFESVCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN82</accession>
    <name>A0A6A6NN82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_388429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN82"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF24">
        <property type="entry name" value="FE(2+) TRANSPORTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="412" mass="44353" checksum="A5BB84AD88CC5444" modified="2020-06-17" version="1">MEAERPQCGGGGLDAETYDLPLHVAAVFLVLGASLFGAGFPVIAKKIPAMKIPPKVFFFCKHFGTGVLIATAFVHLLPTAFGSLTDPCLPPLFTEQYPAMPGVIMMGSLFVLFVIEMWLNGKTGGHSHGGPTGSNMDPSEHSASRRSISNPAPVRRQYSFSSDESWGDEKTDRKVWVEESEVPVAQPTAEAPLPSEMPPWFIAFYQQYARQRDEMMSMISNLMPAAKQERPAPTYTASPELEAGEVDPLVLKKMNLNITLLEGGILFHSIFVGMTISITTDGFIILLVAILFHQMFEGLGLGSRIAQVPYPKGTIRPWVLVCAFGTTAPIGQAIGLLTRNTYDPDSAFGLIIVGVFNAISSGLLIYAALVDLLAEDFLSAEANAILTTKDKVTAFIYVLLGAAGMSVVGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN94</accession>
    <name>A0A6A6NN94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_382335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN94"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="21981" checksum="363A5F40200C624A" modified="2020-06-17" version="1">MLVKTGNYPSIWMRRAALRSSISGGAVATIAAPARKIMTPPPELLRLENKCRITFIFGPEDTWPEPLNDLFLHRTTLYTEYPGLLEAFFTRGVRIPPTHTVALDLFIQLSGSFALGLEALLEAVVAEPEYADLVELSARRTEGAGFLLWAATALCKDREDIMGQMLDAYWCARKDVHMLACIKEGRLEVDWVDVLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNH2</accession>
    <name>A0A6A6NNH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CHCH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_356182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNH2"/>
    <dbReference type="OrthoDB" id="5586401at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039870">
        <property type="entry name" value="Coa4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="3">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="77" mass="9219" checksum="7E547EAF32FA07C5" modified="2020-06-17" version="1">MSAKLDWHATMNTEPADEEPDDWDKRIFSTGCADENARLTDCYYEKKDWRACKHEMEAFRECWKRKGNDKRVETKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNR9</accession>
    <name>A0A6A6NNR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_128623</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNR9"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="52"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="535" mass="58568" checksum="08A4197531EEA5BC" modified="2020-06-17" version="1">MALQSPASISSNNKTSFNNRKQPVEDGVGTDTETPTSQNSPGLLKRFYVGLCIFFLFLNYFLAQYDKFILSYFHDNVLEDLNLRATHYAILSGYATGIVYALLALPTAFIADYTSARVWVLTVAALWWSLCVIFQGLSRNFWQILLARIGMGIGQAPVEALSVSLISDLVGWRNVFLGESCFYVGVYVGEAVSGQIATAFTVTGTSWRVAMKAIGIVGVVIAVAVRTVLREPMRQKGLLSTADEAFDGRLAARSAAGTGATRAGESKLVAARRDMQSTLLYVMRLHSFWLIVLSASFRQLSGNVFGYYMPGYLGNTYSTHPELFSRYGIIVGTVGSVTVLTGGALTSLFWHKTRLTPIYLTAIGGMISSLFVLLMIFSRDIADGSEDQGIKILYGVMCVAYITAELWLGAIYGLVASLLPPAYKTFGIGVWSTVQVLIYSTGPEIIGLALKDVDSSSDEYRKDTQIALAVIIPSGYWIAGIGFLCCVPLLRRDWKSPHIAQRAFSTRRKCGFAIFFALLCSVVITLFTLSIYYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPA5</accession>
    <name>A0A6A6NPA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_424530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPA5"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="52916" checksum="FC080CAE4BB041D9" modified="2020-06-17" version="1">MRYGYSKKPDNFCLPRGQQNSDKTLEYCISTMTFPDNYLTLCLEQASKSPLHYRHGCIIVRGGKVIGQGYNDYRPGFDGGALKTGRIGTGSGGSANPPDAEQDPVADHKRKKKLNPKNSSNGRSGAFTPFEVMLGGGGGGGGPNANTPLSMHSEMMAVHSALAGSACLAAASSAPRLRKPCFKLPGGSKRKARLWRAVLAGYVERVGAGRGGRERAAEAQGQGWRFEAAAFGPVQGQTGDEGEEWSLSISISAPTSVSVRPFFGCGCSITSSTPPSSAKKDAGSKPNYRPCYNESMHSYKDNPPNQSSTASSQPMLLPKGRTGQNNNSISARTKDPRLNGADLYVARLGLDKAISARTKTSHPSPPIRAAPSDADQPASELGSHGSGSLHDELKCPHPRSIRRPPKIPETYDRRIIRSSRPCYRCVSYMQSVGIKRVFWTNDSGEWEGGKVRDLVDALEAGSGRDADGTMLGGSAGNGVFVTKHEVLILRRRMGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPB1</accession>
    <name>A0A6A6NPB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_122025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPB1"/>
    <dbReference type="OrthoDB" id="1112565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
        <property type="term" value="C:stress fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031005">
        <property type="term" value="F:filamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09397">
        <property type="entry name" value="LIM1_UF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000105">
        <property type="entry name" value="Similar to LIM domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24207:SF1">
        <property type="entry name" value="FILAMIN-BINDING LIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24207">
        <property type="entry name" value="ZYX102 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="612"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="676"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="544"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="576"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="595"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="757" mass="81732" checksum="FF8F6D454FE1E003" modified="2020-06-17" version="1">MGDTMRPASFLPSIKCSNCGAEIEISYLADHVCSSASEQQEESPKKEALPKPLNFMDRAATFGSSGMGGLKPSVGGSKPGRMAPPPRIDSTVANKPFLQLDQLTPVSNNSSGYSRSNQSTPMSGAKSPKPPLLRSATSPMPRPFSPPSPDLSSNLDCAFPPFPTTASRGGSTKNETRKNTQKHHEPDARYAPLSPRSNGGASVLKRMDTIAPGPFDTRRGKGAANKEPTGHRRTATTSSDSGKSVRNPSISSNYSVRSKNDSVGVADKADVSIDARPATASESVRGLEAEKTRMGPPPRPARPEPIDDFLERLKNQEPGAPLPSLTKDDRSRTYPLRKDSEDQMEQSGAMDPLRSFEPAVMPLRPHIPRSATQSPSSDRQPSQAQATQFPPRTASRNGTRKDSKPGDIPPVPLAPHLQRQFGANSSHSPTDSASSDGSGFASDARSASSRSSPPMSETFGTSPKQTFGEMDRFARGREMRSNTNDSMGFGSSVRSESPAALSPMDDSRQPFRANAAEPLLPLRAPIASPPESPIDPAIQRGIIAHQRKQSQQSQQSQQSQQSQQSQQSQQRIAPPTIQTNIPRNNSATNLSALTSPSDVSSVGVGKKSASKGNCRGCGNAIVGKSVKAADGRLTGRYHKQCFVCKTCRAPFATADFYVINNFPYCAQHYHQLNGSLCKACNRGIEGQYLETDERAKFHPRCFTCIHCREVLSDGYFEVGGKVFCERHAFHAAQKNTFLGPGRRNPEKRATRIMMMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPH9</accession>
    <name>A0A6A6NPH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phorbol-ester/DAG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_292452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPH9"/>
    <dbReference type="OrthoDB" id="4596934at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="51" mass="6135" checksum="E1DC859E34881690" modified="2020-06-17" version="1">MAQCQHEFHLIKSPYTLIVWRCQTCHSGPHWSIYECKHCKLKVCRDCKDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQK4</accession>
    <name>A0A6A6NQK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CrcB-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_374662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQK4"/>
    <dbReference type="OrthoDB" id="409792at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="709"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="324"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="742" mass="79701" checksum="FBB1D473E85ECA85" modified="2020-06-17" version="1">MASSGSRADHYARQRMSLQPSSTMERRRSGAATSAAEADDADAATVPPEDSLDDLEMAVATFSRGSDGLQRRATRLEAEERRRSRSAGDGRRVSRSYSSRSGASMAPDNRSDGPETATTTTTTPPPLPARSSHSRDRRLSTQQQQQPPWEHIQYAEAPAEHEHQHQQQQQRTGRFEDDFTLPTDLDQLTALEGQQLPPHSLTRHETGGSRRSNPLSSMHRRPSRRSSDYERRLSAVEDRRFDQHEQHQQRRRRRSSVRSSASRWSTKTEPTPEEEAYIELDEEPQLEREEDEEAAAAAAAAAAAQGISPAASGEEEKPPDEESPTGSQEAQQEQQSPHAPRRRGPPTKGPSRLATEVYITAYLILFSILGTLARLGIEWLSAYPGAPVVPGVLWANFAGSLLMGFLGEDRVLFREEWGLEPGVQLDRWPRPWWRRRERTWASPRNLRVDADARAAHAKAKKSIPLYIGLATGFCGSLTSFSSWMRDVFLAMSNELPLPPNPRDASTSASASALLFPATTPRPAGYSFLAAAAVLILHPSLSIAALKLGATLADAAHPYLPTLRFGLTRRVADPACAALAAAAWLAAVVVTAVPPAPAWRPAAAFAAALAPPGALARFWLARLLNARVAPTFPLGTFAANALGAAALALAFDLQHVRLGDGGGGTVVGGGAAACGALQGVQDGLCGALTTVSTWVAEVVALWEAGRRGAAWGYGAGSVGAGVAVVVVVMGGVRWSVGWEAAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR53</accession>
    <name>A0A6A6NR53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_292483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR53"/>
    <dbReference type="OrthoDB" id="269518at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23797">
        <property type="entry name" value="UBCc_UBE2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000061">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19356" checksum="B71D3F8ADB2FF0BA" modified="2020-06-17" version="1" fragment="single">RQEFYVRFKGPEETPFSGGLWKIHVELPDQYPYKSPSIGFVNRIFHPNIDELCVQRPPLPSGAHLSSGSVCLDVINQTWSPMYDMINIFEVFLPQLLRYPNPTDPLNGEAAALLMREPKSYDAKVREYVQKYASKDAADENGEDSESDDEMSSVGSYASGEDEEPAGTMEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR95</accession>
    <name>A0A6A6NR95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_310090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR95"/>
    <dbReference type="OrthoDB" id="73788at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="279"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="476" mass="50841" checksum="91F996C4B09F1E5B" modified="2020-06-17" version="1">MDVAYDHIQEENFPDEDEFRKNENGGDKDNGNGGASGGNAQHRASGSFNTELQDAYRAFSNSPWGARLGGFFGTVRKQGEHYYEEARQEYSAASEQATRGFSDLRETIMNRTRSLSLQQQGASPDDPLAGPPSDDDTTTEKGAASGAAAPSTGVANLPADILHEAENMLSRFRSEAARRLRDIERAEDAADEALLKFGANIRNFLRDAVTIAPPEAGGASGAGAAGGQGAEGGEVLFESKDAEGRRVLHTTRLDASLHAIHASADKFTSDPDSPEFAKWAAGFDVSKQTDAIARDLEKYDELRKTMEALVPEKVEYGAFWTRYYFLRHVVESDEQRRREMLKATAAEPEEEVAWEDSDDESSTPNNTTDQPTIKTPTAATTATGPGPEASQETLKQPSAPPAAAAAGPSDCSGASLKPGAGSPRRSNDQHSSADSDASYDLVSGAPSSRAPSSPKEAGGNGKKEEAVAEESDEDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRG4</accession>
    <name>A0A6A6NRG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_352698</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peroxin-16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRG4"/>
    <dbReference type="OrthoDB" id="2021143at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="165"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="382" mass="43643" checksum="AAAE92BE9510AE81" modified="2020-06-17" version="1">MNAYRQAVPQALAMPPKWLGQYAEFITKNASAVSQIESALRSLTYIIPGRFRESAIASESLHSGVQLLSLYHDSLLAKAIARLPSAQRPHPSPHTRYTRFWTERSPTYRRIAVVLQMIRYTELLWEMAARRRGERVRWRVVVLLETVKAVCRLLLMRLTNSRPLLSPPLPQREVDPSALEEQPSSVSPSLNGTESPPSERSDDAGWTMPRTGLSMPSLPESSDISSYLLSKVLTADDVKPPKALLHRVSGKGELAEILYILRPVAYALAMQRWSSDRKSWRPWLIGVSIEYGARQLAKRDFQERVAGGLRGLTRLEREELRRRGWAMGWWLMRGAFYENITKAWIHGVTKRLRGKPLLDLIGGVIEDYQFLWDEYYFSTATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRH2</accession>
    <name>A0A6A6NRH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rho1 guanine nucleotide exchange factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_291793</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRH2"/>
    <dbReference type="OrthoDB" id="2272012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="5">
        <location>
            <begin position="532"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="666"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="911"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1246" mass="141186" checksum="DC34291C847630D4" modified="2020-06-17" version="1">MADYGSQQGREYGRPPANYGHATNHQRDAAFSSIFGAAPPPGRSQTMTSQPFPNRPIDRAQTMTSQSMASGPPPEMTPRAPPVRQHMNGYGPSGGAPNGYGDGGSSRMPPTPHLQRPDGASMSPVPQQQQQMRQPQPQFPPPLRPDRRPYDGPQRLEPRGLPPGPGYNKPIPNRYPGPSGPALNADPYRSQSMASGPRPQFQGPGAPYGRMSPAQTFRQQPYLSRTTAQGRVVPERPDERTMSMTSYSRDSDYSQTMSGRVIPNRRRESAGQDVPSDTQSSTSSATAVSSPAPGSKTRSPSQSSAPSRTMSMASTITDARTNSLKARSSNATNSTVPPPNATMVSQKRSPLVYPAMLSKVAEVFQDRLPLSEKQKDGLVYQNAFTGAEAVDLIAYIIKTSDRNLALLLGRSLDAQKFFHDVTYAHRLRDTSNEVYQFREKLVEDQLEPQVNGVFTLLTECYSPTCTRDRLCYSIACPRRLEQQQRLNMRVQPGLKREESRSSLHDDQDDQQKLWINTVSKAVADSVDDKEKKRQEVISEIAYTERDFVKDLEYLRDFWELPLRNPARSPIPEHRREYFVRSVFSNLSQVHQVNSRLAEALTRRQQQNPVVRNVGDIFLEHVPRFHPFIQYGSHQLFGKHDFELEKSRNPAFVRFVEETERLKESRKLEVNGYLTKPTTRLARYPLLLENVLKYTKDDNPDKTDIPKVIAMVKDFLVKVNRETGKAENHFNLRQLSQQLVFKPENKVDLKLQEESRELVFKSTLKKTPTENIGDIQAFLFDHAVLLVRSKTVNKREELRVYRKPIPLELLVITQMDEVLPKMGIAKRPSSSLIPGTNKTATNAPKAENTKQAGFPITFKHLGRGGYELTLYCQTQIQQQKWLEHIEAQQRKVRERSNFFTKTILNEGFFTQQMRVNCCVPIDGGRKLVLGTDVGVFLTDRKPKDASFKPRRVLDCKAVTQIEALEQHQILLVLGEKTVYSYSMDVLDPEESQNAPLKRGRKICHANFFKAGVCMGNHYVCCVKTSALSTTIKVYEPMETHAKKQKKTGFAKMLTGSQEYLKPLKEIYIPSESSSIHFLRSKLCVGCAKGFEVVSLETLETQSLLDQADTSLDFVAREEKIKPIHIERLASEFLLCYTDFSFFVNRNGWRARPDWKITWEGTPQSFAVFNPYILAFEPSFIEIRHIETGVLVHITTGKNIRMLHSSTREILYAYEDEMGEDVIASMDFWSRPLSPQSPPHNSQFQEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRL5</accession>
    <name>A0A6A6NRL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_352689</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRL5"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="13">
        <location>
            <begin position="78"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="256" mass="28685" checksum="084A9C89C0F9D5B9" modified="2020-06-17" version="1">MDGSNGCETHQMAPSEIDVEGYNERSPTTPLATSRAQSPFIQHPTIDFDGLSWPSRGTLQRKEATEKEKEECLAKLSGAVRTILECVGEDPDREGLLNTPERYAKAMLFFTKGYEENLSIIVNGAMFHEEHDEMVIVKDIEFFSLCEHHLVPFAGKMHIGYIPNRRVIGLSKIARIVEMFSRRLQVQERLTKQVALALSEMLQPQGIGLVVESSHLCMVMRGVQKTGAITTTSCMLGGLRSTAKTREEFLNLISRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRS1</accession>
    <name>A0A6A6NRS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta/gamma crystallin 'Greek key' domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRS1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025633550" description="Beta/gamma crystallin 'Greek key' domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13461" checksum="6E86705D2842DAA2" modified="2020-06-17" version="1">MKPFNLMVLSFMGFGFGFGRPAGSPQDPTIPTVHAKICQLHNFAGDCYEDTALANDCAAFRAPWVDNVHSFIASAGFICTLYVDDKCIDHNYGYAEDGQGLPNVDDVLISGMDVASWSCGLNDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRT3</accession>
    <name>A0A6A6NRT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_103594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRT3"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF6">
        <property type="entry name" value="OXIDASE USTYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="31718" checksum="88B8B56D4A58FF00" modified="2020-06-17" version="1">MSTVKDPSYHQLPEKDSSESAEEEYLIESNRVRPSKVVGKSTLFYAILLVSSLLSNLFLIVQLSNPASRRNGAQSDEMRTPFAGLVRDTEMVLEKTYVFENETEHNEFWENINVDAGLVALSDEWVREHGLQLGQRFPWDDTKGIYVLEGFHSMHCLKSIHDALTKLKAKRRPIYTWDHIMHCMDSIRKNIMCEASDLPLYSTPGEDPELGIGEVKQCRSWEALTAWSHEHTACYRLINETDAHMDRLERYKFCPEGSPYIERVREVFGDRTGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRV5</accession>
    <name>A0A6A6NRV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRV5"/>
    <dbReference type="OrthoDB" id="17687at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000021">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000015">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="342"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="907"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1142"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="967"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1091"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1142"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1212"/>
            <end position="1223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1268" mass="136459" checksum="3679727198E24A37" modified="2020-06-17" version="1">MFNLSNLVQKAQSFIDPSALPSFAGGAPRSDRPSKATLFRHQFRLPDSQNPLHEITAELTLPSSQSGSNANRPPHAGAAAGAPAPPGTNAAQAAYGAGGADGGKDQYRLPGAHYVGRLHLSEQFLCFSTSGSSFVSSASTSASSVFTGQTHGAGPAGNGFTLPLCAIRRVERLSSQSYMFALAITTWNGFGGEGGAGGKGGAGGGKGGVAAATGSGLGHKFTVQLAGSRQQCERFCDALKRGLREGVKEVEHLKAIVQDCYSEYLIWLDTPEAKESGRDGTKPAREPPDTGLGMMRAFGYPGDARKLRDKSKIRLWREYLRENGRNATLIRQPTFHKLIRVGLPNRLRGEIWELTSGSFFLRLQHPNLYKDTLEKHVGRESLAIDEIEKDLNRSLPEYEGFQSEEGIGRLRRVLTAYSWTNPEVGYCQAMNIVVAALLIYMSESQAFFLLSILCDRLLPGYYSTTMYGTLLDQRVFESLVEKTMPILWEHLVKSDVQLSVVSLPWFLSLYINSMPLIFAFRVLDMFFLEGPKVLFQIGLAILRLNGEELLEATDDGTFITVLKSYFSRLDESAHPKSENPKLRQVTRFQELIVVAFKEFAGITQNTISEQRAKHKEAVLDNIESFAKRTSIRNLGPDSKRLSLNDLGFLYDRFYGVLYERQQRAQVIQMEKDRVARQKLGSRIRATEVVTGIAGNTSVEMGRVALGPSPTQMDYDGFREFLAGIARWAVTDSPSSPQRDPNDAEKSPYYGTNGRNRSVSLPPWGSSPEPADHDFMRRLFHRWDVSGEGSLSLQNVVTGFAYVKGSRDIMSNISYFFELYDDDGDGKVDREGILRISEALLFLSRRGFEGNYLSPASSMTELQPGSAGGAANGGGGVNGENGRSHNRDEMFLSSVSAFIRRCFEYADPDHGLGSKNQQRSTPKQQRVDSNGPPSTSLENFSIGSDDASEDLLDLVDSPEKTRSPKKNTSTAHPHTPTHSITETATTDPLASPPPQSISSPKPDSAANNAALDPSNPLHITLPTFRMVILADETLEAFFESAFADSFRLADAPPTPSSRSASVSTFASSATTPAPRPAAPVAPAGSAAGGPSQGPTPAGAVPPGAGAGPVPGAGGVVGPGRGLRGMLDNIVSDGMRVAAEVKRRMDEAQRELDAASSAAGQQRRPSRAGAEEEDEDEEDEERGRATELLEGADAASVGLGVSTEAGKEGKQEEGQGGGVAGGGGDVSLLDAPVRGEEGREGQGVGQASGQAQRPRGASQGQKSGVVEFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRX5</accession>
    <name>A0A6A6NRX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/hydrogen exchanger family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_374091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRX5"/>
    <dbReference type="OrthoDB" id="5327978at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF1">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="7">
        <location>
            <begin position="25"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="437"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="541"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="582" mass="63497" checksum="7CCDC69B69919BDA" modified="2020-06-17" version="1">MPTLAVVDFNIVCATLGGFISLFGLVSYLIKEKFHLSEALIALVAGLVFSPHAANFIRPEVYALHDAVILDTITLYFSRLVLGVQLVIAGVQLPSRYLRLEWRSLALLLGPGMCCMWICTALLTWAMVPHIDFLHALAVAACVTPTDPVLSNSIVKGKFADRYIPRELQKIVVAESGTNDGLGYPFLFLPLYLIKYLHHDGGAGKAIGMWFYETWVYTIILSVIYGAVVGWLARKLLQWAERNKYVDRESFLVFAIAIALFLVGTVGMIGSDDVLACFIAGNTIDDSLQPTIDMLLNVSIFIWFGANCPWYLFDHSSTIPIYRLIFLGILVLLFRRIPIILLMHKKIHQIEEFKQALFVGFFGPIGVSAIFYLYISLEFLRDIEVNGETRPDAAQLEELFTVVIWFLVICSIIIHGLAIPLGKLGIRIPRTISTARDQRDGAVPRPRVRRGQSSGGAAVDGADESSPSPTPSANGGIMRAPRSRADEYPEDKVHGEGANGAIPGVFFRLGRKVTRRRDTEGGGGMESGSEALEIGPAEDGGPTGSDGRGVPNGGSVGPAARSVEFRGEDRSQGAATAAERGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS84</accession>
    <name>A0A6A6NS84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SUR7/PalI family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_291583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS84"/>
    <dbReference type="OrthoDB" id="4480814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G07470)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="328" mass="35632" checksum="87036DEA13B37E44" modified="2020-06-17" version="1">MGKLGRFACIFVPMGLTIASLICLLLVFLGGLNKGSSVQTGLYFMQADLSEFTANPDLDVVDGTDLDNTLLSAFESAQADDDLKDYYNIYIWNYCSGEENNGSPDIDYCSPRKASFWFNPVAVWGLENTNVEQLFPDELQKGLDTYEKVAKWMFAAYSISFFITVGEIVVGLFAICSRWGSFVTTIVSTASSIMTLAAAITSTALYGALVGTFESVLKPYKIHASLGRSSLSVVWLAVGFSWAAGLFWLFSTCCCSGRSSGGKGKGRGGDGKRGGVTAEKTPYAYERIGSPFLPEGANRSQQHHGAEVPLQNMGQQASAYEPFRHERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS87</accession>
    <name>A0A6A6NS87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_416613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS87"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF272">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="329" mass="35797" checksum="EE9671F9C8E31776" modified="2020-06-17" version="1">MTQKNLYSPYAAEHAAPNGAGDSRPTAIQIVKDEGMIGVLEGKCAFITGCSSGIGIETARALHVAGANVFMQVRNVQKGEEVIKDIQEHSSSKGKIELIKMELGSFESIRKGSPNQFRELRRTILILDLGVMATPETKTEDGFELQLATNHLAHFLLFQLLKPTLWKSATPSFNSRVVCLSSNGHHSGRLHFDNLNLENTYDPWAAYGQSKLANILMANYIDRVYGPKGIHAASVHPGLIKTGLDKFMDPTLLEAMKTKEQGAATTLWAATGKVWEGKGGKYLENCAVAEPAANASAAAQLGYAPHAYDEKAENKLWEVSCKLVGVRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSD6</accession>
    <name>A0A6A6NSD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inhibitor of apoptosis-promoting Bax1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_354278</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSD6"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="31254" checksum="0626CAE96FA00B80" modified="2020-06-17" version="1">MSNARYQPAPTRDSFEEPQRYSQPPPSYQDAEQSTNEALLGGVPRGVDDNMPDDFKFGGVVAEATLDIRMAFIRKVYAILTVQLLATAALSAVSFFSTGYKTWIQTHSWMMWVSLFGAIGFMLLTYWKRKSYPANLLFLGGFTALEAYSISVITSFYDVRIVLEALIFTLAIFVVLTLFACQTKYDFTSWMPYLFGGLWVLIIFGFMAAFFPYNSKVELGYGIVAALIFSGYILVDTQLVIRHYHVEEEVAAAISLYLDVINLFLAILRILNSQNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSI9</accession>
    <name>A0A6A6NSI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_290944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the OST5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSI9"/>
    <dbReference type="OrthoDB" id="5371169at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007915">
        <property type="entry name" value="TMEM258/Ost5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05251">
        <property type="entry name" value="Ost5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="8467" checksum="F099886EE64F4324" modified="2020-06-17" version="1">MSATPLLDVWEAASANPYQPTVSKDSQFTVGFILLLIAFIFTGAFGINRSIATLPLYGIPASLAFGFGAVYMICAVGVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSU2</accession>
    <name>A0A6A6NSU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_290359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSU2"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="238"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="63541" checksum="F94C641F2DF63356" modified="2020-06-17" version="1">MSHSEPFEFITHTAGARAASPSPPQHRLFDAYATLKSAKDVDVDVQLQTALRARYPSLTVTAVPTTSVNLLAFAGAGHAVATPDVSAEDPLVGWRGYVPPARRGDGPGGVARADMFAKYRYEWGGENFIVYGVLVSFYVVQYVLKEPREGETPLSGSRVADELILAVGKWQASAVRTVWVYDRYWVSSAKMYQEAMRISWDDIIMEEGMKKELKGVGNKFFDNKAVYEEYGVPWKRGLIFHGPAGNGKTISIKAMIHTLNSRKLPIATLYVKTAPTTFDIRSIFVRARQMTPCLLVFEDIETIVTNATRSYFFNEVDGLENNDGILMVASTNYLDRLDPGLSKRPSRFDRKYLFSLPSKEQRVKYCEHWHDKLRSKPIEFPHKLCEPIAEITYDFSFATLQEAFVSTLLVLAREETPDGAGDPRGEGYQETSGAGGENAVWSGEADGGDDLERYELWRVIKQQVAILREDMDHEEGSVRRRTSTARSTRDSASAAEMSASTGPCGGDGDAILQHDRFASDLGVGKPRLPVRPVTDVRAAEVAPTALRLDGLESGPGAQAWDGGLDGWDSFLLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT22</accession>
    <name>A0A6A6NT22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_326005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT22"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000016">
        <property type="entry name" value="Proteasome subunit alpha type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="253" mass="27829" checksum="121A6B1E1525DD8B" modified="2020-06-17" version="1">MFRNNYDNDSVTFSPQGRIFQVEYAQEAVKQGSVVVGIVSKTHAVLAALKRNAEDLSSYQKKIIPIDAHYGIALAGLASDARVLSNFMKQQSLSSRLTYDRAISLAEITARIGHRAQVNTQHYGKRPYGVGLLIAGVDAKGPHLFEFQPSGVTQEMVACGIGARSQMARTYLERNLDHFEGSSRVELVKHALRALKDSLSQGRELTVDNTSVGVAGISEDFKLYEGQDIASWLDATFENREEGEEGESMEVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT62</accession>
    <name>A0A6A6NT62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_366222</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the RRP36 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT62"/>
    <dbReference type="OrthoDB" id="448446at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 10" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="333"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="393"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2454453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="427" mass="47089" checksum="68755404AD593523" modified="2020-06-17" version="1">MAKSRSKNPANVPRSRAPVSASDSPPQPHSSDEFEGSSPSILDTGGAGEGQGIRSDDGSYSDGKWDDMESNANTENGDEGLDSSPSYEEDQDDEDQQGAETDVQVQMSKVSFSALAKAQKALDSRRGEGIQRKRKRFESGGEDDGTEDKLAALRERLRELKRQKKSTTGLVGQDSSGRSKKAERGKPGDKAAESAANDASRQRRRKSTQAATLESDGGHSSSSSKTDSETDSDASTSANKKTRRTSKHAPAVQTSTRPVPRARTAVSAPKKRPARDPRFSSLSAGPLDRATVARRYEFLDTYRAGELAELKGALAAAARNPRADPAETAALERALRREESRAAERERRKRVEEVERKHKREERKKVEELGKRPFYLKRSEVRKRALVEKWEGMKGKERERAVERRRKKLAAKERKGMPGVRRGGSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTN3</accession>
    <name>A0A6A6NTN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_291089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTN3"/>
    <dbReference type="OrthoDB" id="4179406at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="331" mass="37996" checksum="5EC09B343F69B20C" modified="2020-06-17" version="1">MVDAISPICHIPGASYLSLPFCRSAELGRSSVKFEDLVNVQDNVAELQTLTLYGKELPAHIRKTELAVRILRPVVRYSDLPSHDELLDELSKFIRDLEEVADALVTFNVKVGRLVDEALLSSRWVLQTLNKLKKRQIWTWLNTFFSSDEDAVRREYLRHCEFLQNHLAKRIEQADNLRNSLRRMESRFDTMGKIIARDDAGIKIDREELLSQLFTRLGGNRESRERLEEQLQLLKQVNSYRIYALAHVMGIMAKMQSMAASLKDLKERVLTPTAAENRRSPPLEIQLYAVQKGAERLQRLVIEGTENGNNQRQIEMAPGEQVRAVSLTLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTS5</accession>
    <name>A0A6A6NTS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_260233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTS5"/>
    <dbReference type="OrthoDB" id="3938895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="14714" checksum="1CB1CA1EEB49C520" modified="2020-06-17" version="1" fragment="single">RAGAPPIEPIPDNCTVTNPLPTPTACGSASSTPVHLSPAPSATAALVYQFHLPPSDLEWRNYTTWWTQCLEQCNGYGYTGDCQTAFMAQNVPAPPAYGLPGGDLGIQCLMYSRPLTSDEFVEVDSDQYSMPTAGVIAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTW4</accession>
    <name>A0A6A6NTW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_81071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTW4"/>
    <dbReference type="OrthoDB" id="5409186at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="17520" checksum="E93AE94A2316D74D" modified="2020-06-17" version="1">MTRRIIAPERLYGRAIATCETANATCAECFGAGNVPCTENGCYNPEGGEQCCGDGTYCVGDTNECCGSALQSSSTTLRSTTSLRTSLRTSTPATTQGNPGAIQSSQQTSIRSTELATSAGNAPSPSTEPAPSAPSPPAETQAEPRPSDPPGQHQLRKSLHRSPQLSSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUD8</accession>
    <name>A0A6A6NUD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_397207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUD8"/>
    <dbReference type="OrthoDB" id="5296889at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="385" mass="40947" checksum="6AD9A1F3607FF52D" modified="2020-06-17" version="1">MFFKRLSRSRADSYVDDDYDGPPSANSTRYEKYDARPSSNRHSLSKDPAAAGPDKDASMYRRPDAPQDAYGGSPTLPRNNSGGLVNGQAGMPNTPGSGGGMGHGAIPPPGGMGDAGFMGSGGTPTKSPGSEPMMPDLLARAFSESVRPYTDKIEALEQQVAELQAWVESLQVQRAEVHAWIDKRGLRPDVPPSIAKQMDASQAAADTLNAQLDRKITIVNFDLHRLQDDLNDSISAAHFAAAMAKFLPDIARLSSLPGGPRYAFDLVLKLGGNLNSHGGLDGGDAADLAARRDFYAQLDDAMVDVVGRRFDEQEDWPVAREIKRIEKTAAYLRNFGVEPYFPRTLDVMRREGAVVGAGGAGGGGGYVGGGGEGVATGQGTPPRYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUR5</accession>
    <name>A0A6A6NUR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_350225</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUR5"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025550924" description="peptidylprolyl isomerase" evidence="8">
        <location>
            <begin position="30"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="52"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="415"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="511" mass="55318" checksum="FA7ED2892AD8798B" modified="2020-06-17" version="1">MLPPANPSASVSSPCWLAVFALAATAVQAIDRTGLRIDITNVVECTRKSRVGDTIQVDYRGTLQSDGTEFDSSYNRGVPFEFKLGQGMVIAGWDQGLTNMCIGEERKLTIPPELAYGDRNVGSIPSDSTLVFETRLEGITGVETEDPVTESPTVASTATSGSAAQSNVVLASPSATATLGPQGGGEEDDGECHLLGPFALLVQGALGVLALTSLVYKRWRETPRRPLKIWWFDVSKQVFGSVLIHVANLFMSMLSSGSFDVNQKAKEAASFVQDATKTQPNPCSFYLLNLAIDTTIGIPILVVLLRLLHHGFLLTPLANPPESIRSGNYGQPPRVSWWLKQSIIYFLGLFGMKLVVFFIFQLLPWIAWVGDWALRWTEGNEAIQITFVMFIFPLIMNALQYYIIDSFIKDPAGGAHEMIPDGEGDEHAHLTRGRQSDSDGESSDEEVEIEDYGKDAGGIQASGPLEEANPTPLPARSGGGSNTDGEGSSRGSTVRSADYGREKPGRPSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUS0</accession>
    <name>A0A6A6NUS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LrgB-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_397329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUS0"/>
    <dbReference type="OrthoDB" id="2502820at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249:SF0">
        <property type="entry name" value="PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PUTATIVE SEROTONIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="551" mass="58373" checksum="0381168F74EBD31C" modified="2020-06-17" version="1">MSERELRSIFRDGVEAIALVARSSWRRLLTAWVYVPIGIMIVLFACFGVDSLIRLSSVSFPASVACMIILFFVLIALEPAVGERRVRTLVQYIDIPGGFALRYINVLFTPSFILIPLGSPITGTEIAKVIGVFVIGYFAMFALTAYLVRLLQLILGTSKRALTERAEEIGPNETNDPGSPSADPSTPSLASSAQPLLPPTPPPEPAPPARTQDPSLITGTGGPPEASTSPSNAIPANPTTLHPFATQSAPPLTRAQRWAAQLNARLDATCHGLLFICVGLPVYYGGPAYAMPAQLCVNVLAYHAALRLPARWRRVAHPVPVAAGVTLLAVWALAASRGEGFLDGLRAYRTRAGYVQMLRGELGAPNTPRPGAGDVLGSVLDVSIVALALPMWQYRKELTRHYGTILVPSLALSVGSLLLYPPLCAWLGISPPRALSFASRSLTLALGMPATANLDGDLSLVAVLCIASGILGVLLGNQLLGWLRIREDDYITRGVAMGVNSSAMGTARLLEVDPRAAAFSCLSMSVFGTAVVVGTSIPPMAGVVRGWAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUZ0</accession>
    <name>A0A6A6NUZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_72371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUZ0"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF34">
        <property type="entry name" value="MOSC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G07820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="191"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="40357" checksum="250819EB7ECCDF12" modified="2020-06-17" version="1">MKVGELFVYPIKSLRGVSIPATQVTPNGFPYDRRFMLMRAADPGPASPPPPTAQWKNMHIAHVPEMALFHVALWPPSSAAAGDDGSLTVTYRAPDEGIERGADAPPTPLRVPLQPKTAGLWTREVVMHRSPTTAYDMGPEYDDWFSARFGFPVKLVYLGGHLRPVLMSTTPDGAQPGQPQQTNGASPSWPSWLSAIARPITGAFGPRKEEITFADCAPFLVASSRSLANVSARLPEGEKMDMSKFRPNIVIDDAPEDWDEDFWAELRVGDDGGSVIHCVHNCVRCISITVDYKLGKFGTGEAGSVLKKMQRDRRVDAGSKYDPVFGRYSFLRARDEGKTISVGDEVTVTQRNTERSRFDWPGIGQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVC7</accession>
    <name>A0A6A6NVC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_380539</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVC7"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000241">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="322"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="723" mass="80684" checksum="5E371FF660D69BB8" modified="2020-06-17" version="1">MDRQSPFSLNLFGSQARDEDDEQRTKRQMLQQLVNFIMEFHLDGVFIYRDQIRENALVHRYYCDIDIAHIISYDEDLAHRLVREPGEIIPVFESALKVCTKRIVHPTRREIELPEHQLLLHSNAANISIRDLTADNVSALVRIPGIIIGASTLSSKATTLHIQCRNCSHTDDIAVTGGFSSISLPRRCARPANEMRDGDKCPLDPYFVVHEKCKFIDQQVLKLQEAPDQVPVGELPRHILISADKYLTNKVVPGTRCTIMGIFSIYQAKGSKNSQAGAVAIRNPYVKAVGIQSDVDHTMKGNAFFSEEEEQEFLELSRRPDLYEVFANCIAPSIYGNQDIKKAIACLLIGGSKKILPDGMKLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAIYTSGKGSSAAGLTASVQRDANTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPIFGRYDDLKTPGENIDFQTTILSRFDMIFIVRDEHERGKDERIAKHVMGIHMGGRGVEEQAEAEIPIEKMKRYISYCKQKCAPRLSPEAAEKLSSHFVNIRRQVHAAELSANARSSIPITVRQLEAIVRITEALAKLTLSPIAAEEHVDEAIRLFLASTMDAVNQGEGQASRELMEEVNKVEEELRRRLPVGWSTSLATLKREFVDGRGYSEQALNRALLVLQRRETVQIRHGGVQVYRSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVX0</accession>
    <name>A0A6A6NVX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_365137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVX0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="327" mass="36769" checksum="6228BC3E9C86E4B9" modified="2020-06-17" version="1">MSNTGTTQSLSSETLSTAAKMLYAFMSILDPTNMSQAILKDALEKDLLTHLQAPNRPRAIRPFDSVKEQLVCHGFVHQDKLTETLQMYTSVAESVLEIRTVGPWKSSPSYDREIASHVWTLQKAFGDTIEDTNDALGKDRKTAMLFLRYAKFALFAGQMDKCRRVALLAKCVFAFLRSRVNDSRYSLSIVECDHAISVALMHTTPSNTLNYAEKSLAGLAQLEATSENHTQEYALAKARAYNQQGLCQVLANSERQEIISSFESSIRISVTTDQTLFRGALPATNLARYYILEESPRRAEEVLETHGWVQQAQNIGEEDDMMLFFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW21</accession>
    <name>A0A6A6NW21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_386780</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW21"/>
    <dbReference type="OrthoDB" id="5558646at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF17">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025411557" description="AA9 family lytic polysaccharide monooxygenase" evidence="12">
        <location>
            <begin position="17"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="13">
        <location>
            <begin position="17"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="235" mass="25447" checksum="D762AC6785A12030" modified="2020-06-17" version="1">MKTNAFALLFAGAASAHTIFQRVGVNGAMEERYKYMRLPTYDGPIQDVTSSSMTCNGPPNDIVMVSDAVLDVPAGADFTLQWAHTLDTDFQTGMIIDESHHGPVMVYMAKVADATGSAPQSGWFKIYEDGYDSGVWAVDKLIDNEGKVTVKIPECIEEGDYLLRGELIALHAASNYPGAQFYMECAQIHVTNGGSAAPQTYSIPGIYSGSDPGVKFNLWGQFSSYEIPGPDTFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWF2</accession>
    <name>A0A6A6NWF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWF2"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01519">
        <property type="entry name" value="RHOD_HSP67B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="88"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="20747" checksum="F63BF653FD85546D" modified="2020-06-17" version="1">MAARRALFRLPLRASSSAALRNGAAASRYASSLASAGAQPKWAATAVLPAQWRLLGKRAGGQTRWYSSELGVAKEYKFDDVKQLSEKPDENVQLIDVREPQEYANGHIPTALNIPVTTQPDALFLSPEEFEDRFGFAKPATDKGVIFYCKAGVRSATMAQLAINAGYKDVGEYKGSYMDWEKNGGKAEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX72</accession>
    <name>A0A6A6NX72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_347823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX72"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="193" mass="20889" checksum="953BFD31671EAB91" modified="2020-06-17" version="1">MPPAAGLFDIPCSNTSARETAGYRFFDLLYPDLTPRSIALAKYCEGLVRGPLEEAQQRRSASALLQPSAVLHPSTAIGAVPQSSYVPTIVTSDSKWRKNAVEPAYGLPSSPEWFSQGSGGEYLMYNGRTQSSMLMGSRVRSEDDAARLNSGGEPEVVACRVPELSSLIPRPGSMHCLVPERWDMPGQKTGVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ11</accession>
    <name>A0A6A6NZ11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_41525</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ11"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="PITH" evidence="5">
        <location>
            <begin position="131"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="340" mass="36738" checksum="B99255938A8AFA3E" modified="2020-06-17" version="1">MSKVVHISSPEQFSSLLASSRIVVVDFFAEWCGPCKAIAPLYEQLAARLSRHNSVTFTKVDTDKQTQIAGSYSITAMPTFVIIKNGHEVSRIEGANPQQLSDAVRKLAAEAEAGASSSSAAGGFASGPVWRGANLPRGYHDVTDEVDRTGLELLNSDSDFGAARVLLDPSEPSALKATGNAGGGKGKGKAEEPGEAARDWVQSDTDEQLMLFLPFNATLKAHTIHITSLPPVEADEDEVPMRPRTIRIYTNRPHNLGFEEADDTSPTQAFELGPDDWDGKTGTAKLELRFVKFQNITSLVLFVVDGDGDGEKVRIDRVRIIGESGEKRTMGKLEKIGDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ15</accession>
    <name>A0A6A6NZ15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ15"/>
    <dbReference type="OrthoDB" id="5414615at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="317" mass="35050" checksum="908D48B2F43DC951" modified="2020-06-17" version="1">MFDSQNCTVVPDDARTDPGVAGAGILLSFIITAGLSIVLSAVIILYELRGQSKAKISRKMLQSMSDQQIITGIGIQCVGLAKMTTMIPYHFFIVWMLSVLSTATHIATLLALVNDFRRDWVLRWLRQFLMFVNLVLSCVSGIFVLMSVMKGLEPTLPIACVWRVDDRPKPDDAALSVAGTIAVLAGNCIVFVLGVWYLHSKRQPWVKTVQVFGLVVLVAIAVGSTVRVILMSQAFGDPDLPLRGASEKDWSFGQLLSVLLLIMPLISAVEIVRGEMKVPSPLPDDRKPLFHEEEKHNVRQSFQPNPFWGSQASLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ49</accession>
    <name>A0A6A6NZ49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ49"/>
    <dbReference type="OrthoDB" id="16816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050602">
        <property type="entry name" value="Malonyl-ACP_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090:SF1">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="350" mass="38467" checksum="B4BCCA00E50A4BD7" modified="2020-06-17" version="1">MRPSLGRFGYPKSVRGYAVQAPGAPTLDVFSRRTKWLQKERAARDAETSRKVDYVRDEVAARLCERLLDIKRHFPHVLDLGANACNIARILTRPNPDSYSAAPVYEPLSSRVSALTAAESSRSLLHRDEDLPFNNEIAITRHLLASDETLPFAPHTFDAVLSSCSLHWVNDLPSVLTQVNNILKPDAPFMAAMLGGDSLFELRTSLQLAEMERRGGIGIHMSPLADVRDVGGLLQRAGFRLLTVDVDDIVVDYPDSFALMADLQAMGESNALAGRDVPPIRRDVLVAADAIYRALHGNDDGTLPATFRLIYMIGWKEAPQQAKPLERGSGMVSIKDVLEGQRTGGKSGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZI6</accession>
    <name>A0A6A6NZI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="11">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_286114</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="11"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZI6"/>
    <dbReference type="OrthoDB" id="10263824at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="192"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="627" mass="67314" checksum="61CEBDD769D17706" modified="2020-06-17" version="1">METIIRQAGAVCPFLKKTPPSTLRSLSTTTARNASPGGGAMSNLQVIARRCPIMGKALAVQSAKAGNAALAGVYGGARAYHTGKTSRAKLHTTAPKMAQAADAGLAHHKQQRKFPRLVPHYPHAAKKPAETSPQKYPGCVPPPPKPLKFDYDGFYQGELDKKHKDKSYRYFNNINRLAQEFPRAHMASKEDKVTVWCSNDYLGMGRNPKVLKAMHETLEMYGAGAGGTRNISGHNQHAVALEGTLAKLHAKEAGLVFSSCYVANDATLATLGSKMPDCVILSDSMNHASMIQGIRHSGAKKMVFRHNDTADLEAKLASLPPEVPKIIAFESVYSMCGSVGPIEEICDLADKYGAITFLDEVHAVGMYGPNGAGVAEHLDYEAHVAGRPRGTVMDRVDIITGTLGKAYGCVGGYIAASARLVDMIRSLAPGFIFTTSLPPATMAGAKAAIEYQMAFQGDRRLQQLHTRAVKEALAARDIPVIPNPSHIVPVLVGNAELAKQASDMLLEEWDIYVQAINYPTVPVGQERLRITPTPGHTAEFREHLVEALEGVWNKLGIKRTSEWAAEGGFIGVGEAGGEAVVPLWTDAQLGLDGLKGVNIEKETAGAVLERVLEDERKHVLQTAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZK7</accession>
    <name>A0A6A6NZK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_364096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZK7"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070880">
        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="2">
        <location>
            <begin position="442"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="822" mass="89897" checksum="B13CAEA81946ADA9" modified="2020-06-17" version="1">MTMLPPIVGLFQAVASATGPSRAKRPRSWWQRMRAAASAADHPSDESTCATASRAHPWADLWTPRRAERGQGRGLRHKSPRDVQRCPRRRARESAAGVGWRPSVGTYLELCTCSLLLWDRDALLWLHGGRREEAGGSVRRGPLSLWLHAAPRRRHRGRFQAPSQNITFARYAKQKGPSERRRELVSAGAYRGDAARASGPFLGGNEIIAAAGPGRSPSATVLSLYRYLRSGACDLTCAARPSLSLPLAPLRPASVAVKSPCLLKPEPCRTWHHPRDTHGNGQADVFLTSPRLASSWRSFWHTMTSNDRHASHDSPYRTGQHVPLPQSRHAPLTSVATSAMESRTDLASPYPGDDPASGNGYSHSPKGPLSPKAPYSPGLRSVMSRQSADADAFSDKSPTGEIPMQSFSDGLPPPPPVSHSWKRIDHWAESHYEELFDNLCEGCTQNDVNELEHELDCTLPMDVRESLQVHDGQERPGLPTGIIFGCMLLDCEEILLEWQNWRKVNDEYLTQRSFNAPQPPMKAFGGAPSSAASSSSAPPLPQQPSPTNSIWRQDLLSRQDSQPPGAVQKAYAHPAWIPLARDWGGNCLAVDLAPGANGRWGQIIIFGRDYDCKYVVARSWGAFLATLADDLSSDKVHVDEDSNELKLLEFKRQNVEPPYLEILRWRCDQKHGRKAPRRRPNGPGAAGLRINSSVGGTGLNNGSPYASPTTSLGEERGRSPHRFSGAAGKVPAGSPRAHLSSPLARVAEEAPKPIRVHTGGSTKEEKLVSIDTPRPSEDRSGIMSPLRETTNVHDANKKNVNGSKTEEKDVADNPAGMKTVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZQ9</accession>
    <name>A0A6A6NZQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_385912</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZQ9"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000791">
        <property type="term" value="C:euchromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000021">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2457017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="142" mass="15271" checksum="28D000D7F366085F" modified="2020-06-17" version="1">MPGGKGKTGGKTGGKAGDTQVKTTKSHSAKAGLQFPCGRIKRHLRNITRQKTRIGAKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPHINRALLLKVEQKKGKKAQPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P001</accession>
    <name>A0A6A6P001_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_392624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P001"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="243" mass="24517" checksum="1847FF357E63158D" modified="2020-06-17" version="1" fragment="single">CTSSRPSPPPPLSPPSRTPSPSPPPTPSSAAPTTPPPPARPTPSTSAPRPAPAASSAVSPPPTAPPPATAPAASTMTAGPTAPSARAPTPPASPSSPAARPTPPSATPRLARPSRRPRPRPRRAPTTATTTMPRALRRRATAATAPTARTPRPSRPRSLPRSARARPAPCTSRTACARAATWGALLPRATPRCAVGASASGARVRRGTGTITCVGTGSRGARLRGMCAIKGVDCFCSRSIFHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0N3</accession>
    <name>A0A6A6P0N3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_421641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0N3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="200" mass="20826" checksum="108D463108F80D48" modified="2020-06-17" version="1">MAGRATARGPSYRRSHLLTDRAIGEERARASCGRVLTSRRRATACAKGCREGSTNGGAYGWSHGASRSAPWLVTTAAGGQKGGEAREDGGRAGGGGQRAARARRGAGGDQTSRVNVAVERRGRTSLTRGRQATAAVISGRAPPRHLRAGQAARAQLSCERPRPATCQPYSLKGTATGAGPKSREPQANDRRAQQVTVTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0X3</accession>
    <name>A0A6A6P0X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_371936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0X3"/>
    <dbReference type="OrthoDB" id="10265668at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="11262" checksum="D250A5BA39E284A8" modified="2020-06-17" version="1">MSHPFWDKYLKFEKRVEATDRIFAALDLVVHIPLHQSTRYLEWHLQPLIPAQLTNWRHQKSSTISRKELASSRLIYARTQLETTKRWQFEQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1E3</accession>
    <name>A0A6A6P1E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal protein s17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1E3"/>
    <dbReference type="OrthoDB" id="2336871at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025525345" description="Ribosomal protein s17" evidence="2">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="38950" checksum="950B0DBE3A875702" modified="2020-06-17" version="1">MRFTTILTLAVSASLANGVVAQNFGNNSNNGNNGNNNNNNNGNNNNNGNNNNGQDDGQDDNAGDADVLQLDPDLVQDASQVDGLGDDAEDGQAPSLTDDANFINFCSGKTVTNGLQVREGSCNGIVMGDIPAQDQMTTAIIVNPLPGDDLTENEDFDIQVQVNNLVAGFFTNPDNTYYAAPQQLTNGVVTGHSHVTVQDLGGSLAPTNPPDAIEFTFFKGINDDGNGQGLLSATVPGGLQAGFYRVCTMNAAANHQPVIMPVAQRGAQDDCTKFTVGQGNGGNAGDDADADDDAGDDGQDDGQDDGQDDQGNNQGNNNNNNNNNNNNNGQNNGGNNNNQGNNNGNNGNNFGGNFGNRFGRGRGRGRFSRRAFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1I1</accession>
    <name>A0A6A6P1I1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_275553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1I1"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="44206" checksum="C5C9003DEFD83FFF" modified="2020-06-17" version="1" fragment="single">PVLPDDILHLICAELSGRRDFDTLFNCSVACKNLAVPALTHLYRFHHDAPLKDMEPLAIAQQELIVQKWSIMWRSIILSSLPGEKTMYPYSRYLRVLDMRDLKYLLEEDKFRSKISRTFFAGDLARFRIVDNTTPKSGRKAFLKLNYSAIIEAVGDVITEHTPMLEQLSGDIPGSALIRWAPRLPRLRSLELGDSRALGEEGVRAVLPAHCPHFDSVSLYFWIESDSDHKLATFLSSLRQQSLRSFTVISEVGMRAETFLALNSHSAALRELKLFFADAAIPHLSLLKACTSIDTLELNASSNIDLERTQNDVFLETIEWLRDCKNLRSLSMSGLLSGAAIVTPLLSDPEIRLQKLKVDAYMMKDHRHFHLGLANQKDLQGLFLVGESEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1P3</accession>
    <name>A0A6A6P1P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_302730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1P3"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36504" checksum="5700CE69A6A7B096" modified="2020-06-17" version="1">MNKMPNFSELPLGKDDPPFSAWGLYGKDDQLGTLNRLTDDIVKEAAKEIKTGVRISMNWPLDAQADMPFFRRQAFHKHVYPKPPRVVNDDVWTFNTQSSSQWDGLRHFAYQHAERFYNGVTMGDIHASPSSTVNGIHAWAERGIVGRGVLVDFAGWRAALAAQGQAVRPYDPFETGVIKLEELKQCLEWQGTQVRWGDVLILRSGYMEAHQTKPKDELKVLAEVVPPHFSGVEQSPEMLEWIWDHFAAVAGDHPTFECWPSQQSEWSLHEVLLSGWGCPIGEMFDLEGLAAECKKINRWTFFVVSEPCNVPGGVASPPNILAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1X2</accession>
    <name>A0A6A6P1X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Complex III subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_343855</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the UQCR10/QCR9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1X2"/>
    <dbReference type="OrthoDB" id="44067at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.260:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.260">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008027">
        <property type="entry name" value="QCR9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036656">
        <property type="entry name" value="QCR9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12980:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12980">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05365">
        <property type="entry name" value="UCR_UQCRX_QCR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81514">
        <property type="entry name" value="Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7814" checksum="E82D4169443ABCE2" modified="2020-06-17" version="1">MAGVLSTLYQGLVRTNTRYLAVIFGSAFAIQLSFDKGSDKLWDTLNSGRQWKDIKYRYMEKDEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P274</accession>
    <name>A0A6A6P274_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_22447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P274"/>
    <dbReference type="OrthoDB" id="291792at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF19">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="63733" checksum="938746D187A4D8FE" modified="2020-06-17" version="1">MASSSSSVSSSSSSGSGRESVDPVLRNALRYTVSAKEYKLLHRYLISRAPAVRRRTLQPRRYETVVTGSSADDYNAATVRAALRVFGSIYGGLKLWDLFTQKVLNRGKPRLPSPKIPFWKSPNFRLSSSFALILLFHRLLHRFFIRLRESLLTENARPFRQRNPRVARTLTSRLAPAIGASLSGFFLAVSPKDQLRVTIAIYLFTRALEFSYNRLENKGYFKDRPLWFGSWLLMPAVFGQLLHAFTFDRDCFPEEYGRFILNNSPQYVQKRPANYPAHLPWPGPYDIADSLAEISRLRWPKFTSPILFPDTQTLPSSLSAIAPITSSAHPATTNLSCAVLHPHDPSCLRTYITYWLRAFPRVARFFTLAFTAFALVAKPFRQQLVASPISTLNALAARILRASAFVTGAIGTSWGAICLLQSGAVAPLLLPHGALPRQRWFLHGALGGCWAILARSGGRDNFLYSARVSIDSAWKVGVKHGWWKGIKGGDVLLFTASLALVDAVYEVDPKAVSGGMLRKGLGVLRGEGWVDRAASAKGEGEEGKVVEERESEASGLEGVDRIEEEAEKAEEKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P283</accession>
    <name>A0A6A6P283_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P283"/>
    <dbReference type="OrthoDB" id="3484559at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025388872" description="Ig-like domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20990" checksum="26DD089A16C4E684" modified="2020-06-17" version="1">MQFRASIFTAMPLLATLVLAAPTSVAPPTNMRRSNLPEGCEYDSTTSLTCSFPTIHPVINSNSEDACRTDPEDASHTICTATGGIARIYGSRPIAKRAAETADTAYKFSLECDLTGCEHDTVDRRAVEQEEDEAYKLTIEWKRDVEETVAKREEAQNEDEAYKLSIEWKRDLQETEADEAYKLTIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P300</accession>
    <name>A0A6A6P300_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Six-hairpin glycosidase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_284415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P300"/>
    <dbReference type="OrthoDB" id="4104179at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF2">
        <property type="entry name" value="ENDO MANNANASE, GH76 FAMILY (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="63574" checksum="DC4945F06162A474" modified="2020-06-17" version="1">MGGDVDDSLHDVIRFDAQRHPPAGSPPINPLEELHYALETMQTHFFELWLGTWPNSIDWTGAVLGTYVDAALYTLTNSLEYILPTLEGAELPVEGQRVENEINKYFSQVISYYFGENDFAIRTQAHDDMLWVVLGWLQSVRFIDLHTAKHYPASRRGASGEWYGVQFMSAFAHRAHVFYDLAAKGWDTKLCGGGMTWNPHLRPYKNAITNELFISASIEMYLYFPGDRNPSPFVAGSDAGSSADAGAAGIPVAKPHDPKYLRAAIDGYAWLKDSNMTNERGLYVDGFHIHGWSHNGSIGTGKCDERNEMVYTYNQGVLLSGLRGLWESTDDRSYLEDGHTLVRNVINATGWKPKPDSSGSAGSNNGTGRWAGLGRGGILEEMCDAAGTCTQNGQTFKGIFFHHLTLFCAPLPRRPLVPGRTYAATPVEASLHAQSCKEYAPWVAFNARAAMKTRNERGEFGMWWGWPAGKGHLDGDRRGFEAPPLPDGAVDYRNNASALLDWKWSGFRHGRVPSTPEWRRRTWAASSQAHAEAESGNRDANDRGRGRTVETQGGGVSVLRAMWELVKMYGGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3D0</accession>
    <name>A0A6A6P3D0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_378680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3D0"/>
    <dbReference type="OrthoDB" id="5376498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="18850" checksum="181F2DDA4C124C8B" modified="2020-06-17" version="1">MPSAEPSSQMWIVRLKYRSTTVMLHADPVSTVDTLKKELLVALKETCPDGMLEGEPLPESHEAFILAQSKDKHDARKGWDRLDPSSIKGLDDEEQIGRKKRRKSSVERYGATPLKETGMRDDPLLAFKWRPNEKTELGDGFDILDESDDEFDVVLPTFDDEMDEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P469</accession>
    <name>A0A6A6P469_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_284098</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P469"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="24095" checksum="6EA2907747FEBA93" modified="2020-06-17" version="1">MGALKYVEELQKKKQSDVLRFLLRVRCWELRQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKKPVPKGATYGKPTNQGVNQLKYQRSLRSTAEERVGRRCPNLRVLNSYWINQDSTYKYYEVILVDPQHKAIRRDPRINWICKPVHKHREARGLTATGKKSRGLGKGHRFNKTTAGRRKTWKRNNTLSLWRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4A2</accession>
    <name>A0A6A6P4A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl hydrolase family 13 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_210002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4A2"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000023">
        <property type="term" value="P:maltose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="2">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="13045" checksum="A10DFAD99E852C2D" modified="2020-06-17" version="1">MTVPVSEISDDIPDHPSINAPYELVKDFKPLMSEGPGRAMKLILDLVANHTSHLHKWFLELRSLKNSVKSDRYILGTVEYRKGVAGANCTTTLVAAPRNMKEGVCVLPPSSFARNNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4W4</accession>
    <name>A0A6A6P4W4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4W4"/>
    <dbReference type="OrthoDB" id="3928392at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="195"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="478" mass="53111" checksum="CD4CB9D132050352" modified="2020-06-17" version="1">MSEWLSTPAGGVPEVAPPIDLLMAAVDSRLRDFQSYEPSDKSNNDNTDTPVHEYQALSMDENSEAEQDMSSGYGEAVYDDDLVEYYANSSPRKLEIKSRSNSFDSHSEQTPSDEADGIGKDQYSPDTGSIFQSEAQLVARSPSQSPVRSSTPSPIGSPIPDESPADGLDSSPVTQDNEILPQPKAPRPLPPSRDNEELLGAIIKLRVENETLKETNDIKQFAIDELVSQRDEAMRVSRELKKQIGEYEALLKSTRGMINDLKKHQSRTVASAVDMLLDKTGHAVRDNSVWMRANWNSRASSRTHLRVAEEFFSNNQLQQALVELSRLLTQSPPLPLPVQVDALLLSANILRESGSFNDAIMKYLAAALRICSANKDKDMFVERGRVCFYHALINADLGRWLEASLLFSSASNTPGMEKEANTWFELCRNQHVKFRGRRAKALSRGQPWPEATDTIAYGPLSTRTELLGLRSEAAPRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P566</accession>
    <name>A0A6A6P566_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_196563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P566"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17263" checksum="07939BF6E0C9482E" modified="2020-06-17" version="1">MPSYIHTYIHTQHAGRARHAFDAWPAAATDGGCRSEPNRAFWWERGPSGAEGPPKGPLGRIDDMHLCPSCRGDGTGSVANRSSRCHHVPAYTRKSWRCRDRGDGSIKSALRIVNVISDGVFRSGGPRIYDLHRQARRPPRYAQHHPSVKWFASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P591</accession>
    <name>A0A6A6P591_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_283528</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P591"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="86"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="342" mass="36190" checksum="50515AA50B7A6136" modified="2020-06-17" version="1">MNATSRALLSPATTGALLLVLARGPARLRAALRQRVPAAALARLLRALAALFALGLLARANALLSAWAKNRWQVPGRGRRRRWADEVAVVTGGCGGIGAAVARGLLGLGCKVVVVDTVPLPESLGDWANLTYEHCDITSPDSVHQAADRIRAQLGAPSILINNAGLARPAPILSQTAAALQAVFATNLLAHWTLLQAFVPDMVAAGAGHVVGVASLAAFVTPAGFADYAASKAGVVSLHEALAQELKHRYACPRVRSSVVCPTYVRTPFVEPYREGLRKAKALTLAPRDVADAVVAQVREGRCGVVVLPERYGWLAGLRGWPAWVQEFIRDGTREHVTGKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5H1</accession>
    <name>A0A6A6P5H1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_370694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5H1"/>
    <dbReference type="OrthoDB" id="10248398at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="3">
        <location>
            <begin position="170"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="229" mass="23450" checksum="7A52AE87DF58D741" modified="2020-06-17" version="1">MFGVIVSGRPVLTDSHAITPNQLAFSIPTSPPFSHIVVFLLPGAQLPADAAAAVYVQIPPSTDFTLLGALAADKQSAIFKLSGVGGSMSNQSGAGGAATDDVMVDEATGAADRQQAAGPPVTLGISIEPAQQVAAALAAKGQSRTGPGAGLTGSELVKQQPGMAHRSSVPTKVLAQRIIANAFNFLASFAGNTGPSGAEVVPLKSFQDWWAKFEKKVELDPGFLEREEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5W3</accession>
    <name>A0A6A6P5W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_340085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5W3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025443514" evidence="2">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="7402" checksum="BE069A4F328CB06B" modified="2020-06-17" version="1">MQAAKREFFLSLSLSLSLSLSLSLPFSRRAHDKVPAEKLVQATSGAIPPRKGLLDLPVAKPTAPAPPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Z1</accession>
    <name>A0A6A6P5Z1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tubulin folding cofactor D C terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_340160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Z1"/>
    <dbReference type="OrthoDB" id="10253476at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058033">
        <property type="entry name" value="ARM_TBCD_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033162">
        <property type="entry name" value="TBCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022577">
        <property type="entry name" value="TBCD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658">
        <property type="entry name" value="BETA-TUBULIN COFACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23579">
        <property type="entry name" value="ARM_TBCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25767">
        <property type="entry name" value="ARM_TBCD_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12612">
        <property type="entry name" value="TFCD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin-folding cofactor D ARM repeats" evidence="4">
        <location>
            <begin position="343"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="351"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin-folding cofactor D C-terminal" evidence="3">
        <location>
            <begin position="910"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin-folding cofactor D C-terminal" evidence="3">
        <location>
            <begin position="970"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1063" mass="116642" checksum="746DCD91BEB1232C" modified="2020-06-17" version="1">MNPTTEDDDLLLQRASANLLAELRTRIDKVLWKKASASRDVARTPHRYVKERDLWRTLALLDPFQGDPQLLDTHLKFLLPPLVDAYLQTALSKEHIDSTKPFVPLPRAVCCILNSFCKVRGEKIIIGFLNNEPRHLEPILSAFERGTVENRDSTKRTKNPGLVWEERYILLLWLSHLLLVPFDLASISAPAQQCASLPEDLTGLPKDLPGIPIRILPIVLLSLRSATKERFAAAKLLVKLCLRPDMRAAGLLDCLTNWALASVKASETKSVHIHKNIGLLSFLSGLVSSGTVEEIGKYLAPIYHTCAALPEEVSSSAVARKLVIKTYREIANHSLQPRVDFPDLEGVMEEIIESLLQSVGDGDTPVRYAASKALSVISLKLQQDMAEEVIEAILGYLNENVLWEGNIRDLRAVDPLQWHGLMLTLGHLLYRRAVPNSQLPAVLNSLILGLNFEQRGTTGGSIGTNVRDAACFGIWSLSRRYTTKELDSVDTREVHSVNDVGETQSILRALAVELLVAACLDPVGNIRRGSSAALQELVGRHPDVVDHGISLVQVVDFHAVGLRDRALGDVALASGRLSPLYRRALFSGLMGWRGIGALDAASRTVAAKSIGKLSMFDNFEHVDTCSGAIQTSLAETPKRDVEKRHGIVLALTYLVEECVESSMTDSKAIRATCSLTQLWQLFDGPLALKEENFTSVSLRPEVTAISILSLISALAELSLFVIQSSSSAVAQWNPRVMQTLDYCLRRTEDSVHSAIPSCVQRLGLLLPKEERRSISKSWMDTFTYGSKISSRPSGHAIALGAIYCTIENAAQRDHTAILDALASRCSDIVAIEARVVAVKSIQLTFPAIKLDEPKLISKVAEALVTGLNDYTINQRGDVGSLVRLEAITGVSNAWKQGLLSHGFDSAGTEQDIFAAMLRLSVEKLDKVRNQAGQCLDELESTSVNPSTFSSFGYFRHRLSSVFEPPIKPRWARRGVLAGYVTAAGMGSESVLQASRLALVDLLETMPAEYSHPDDGSILDVANILTELLRDNLGTDRVVLPLLEVIAFLFDAGFLQKLVGTEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P696</accession>
    <name>A0A6A6P696_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">mRNA 3'-end-processing protein RNA14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_338432</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
        <text evidence="7">Nucleus and/or cytoplasm.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P696"/>
    <dbReference type="OrthoDB" id="26282at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180010">
        <property type="term" value="P:co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000006">
        <property type="entry name" value="CFIA complex component Rna14, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="9">
        <location>
            <begin position="214"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="599"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="843"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1008"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="865"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="939"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="951"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1017"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1051" mass="115695" checksum="F8194CB5FBCF1D6F" modified="2020-06-17" version="1">MADNEAELAFLQSMQASTPVVQDAPYQAPSQPADDDDDDYDPSNLLPDRAQAEADNADDAPEQPESRAPSRAAQPPEPAPSSAPAKQAPRTMGGFVIDDDDDDEDDTPIAPSGVPEANGVLKGAGISRHTPQRSVSQTPTSGIPAPSSDVQIQNAAAENQGVSGAPIGAATDSTVPTIAVPDSASANIASDSNEHTQALPISAHVLPKPRLSHDRVGALEDRIAEDPRGDMDAWLELLSEHRRKNRLDEARGVYERFFKVYPSAAEMWAAYANMELENNDFYRVEQIFSRTLLSIPNVQLWSIYLNYVRRRNNLTSDPTGTARQIVSQAYDFVLQNIGMDKDSGEIWQDYLRFLQSGPGTVGGPGWQDQQKMDLLRKAYQRAICMPTRAVNLIWKDYDEFETKLNRATARKFLQDKSPAYVTARSSYTALQNITRDLNRTTLPRLPPALGFEGDVEYMQQVDIWKRWITWEKEDPLVLKDEDQAAFTGRVVYVYKQATMALRFWPEIWFDAAEFCFQNGLESDGNEFLAQGTTANPESCLLAFRRADRIELTTTAEEGDESVRRRGEQVREPYDKVLDALYELIKKTQARESQSIANIKDMFAQQRSPPSSAKDDDEDEEEENAKAAAKEAAVQAQIEAVQKGFAAQIKLLSKTVSFAWIALMRAMRRVQGKGKVGDLIGGSRQIFTDARKRGRLTSDVYVASALLEYHCYKDPAATKIFDRGMKLFPDDEIFALEYLKHLIAINDITNARAVFETTVSKLTQKPDSVSKAKPIYAFFHEYESHYGELSQVTKLEKRMADLFPDDPTLSRFAHRFTSGNFDPTAIRPIISPGSQAKPKMFMAHPGDFTSGPPVPPPIGSVIPSVEKPPPTQLPINPPRPTSAAGSIRDSPRPPYAQSLAPVAATASPKRPFQPEDSDTESVGPRKLARGESPLKGAAGRRLDQQKRRAAEAGGGGAGFGAGMGNSPLPLPRDITFLLSIIPPAETYQASIFNADKMVNLLRTTDLSNANLTGQTTTPRPPQPPQPPQPPQHQYGGYGGTPVQPSGGFSYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6C8</accession>
    <name>A0A6A6P6C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_370259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family. PalB/RIM13 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6C8"/>
    <dbReference type="OrthoDB" id="167576at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25435">
        <property type="entry name" value="PalB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="114"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="919" mass="100337" checksum="6D61D3BF1BCCD09C" modified="2020-06-17" version="1">MSAAPTKDEALAMAVEAVELAMSLLKLSLSSSDRAELMATCHALLQEAENVKKSNGWPLSSTSSVSVPAAVEKTKKAPASTRIQTRAEQILLLKGSLFGSDKFVMWESAPSPSEFSLAPDGSLFEDAAKLDLSEFQNGILECWSRAEDALVPTSMKKYNGLPPGQSLLDIDGPASLLKMDMDLKVDLVQDAACDCSVVASLCAATALAEKGFPNIFASVIYPKANNRPVVSTNGKYIVRLNFNGSFRKVVIDDYLPVSRDHRTLHIVDRNNRTLLWPALLEKAYLKVRGGYDFPGSNCALDLWTLAGWIPEQVFTQDNEQPMADLWDRIFTSFRRGEVLVTAGTGKLDKRSEEHLGLESQHAYAVLNLKEEDHRKFFLIKNPWSKGTSWKGTISPPSMSASSPATGSRSSLLDEALDQNVNFPALVSLTNGQPGTFPRPNEQLTPGTFWIDMENLLQNFETIYLNWKPSLFTSRQDIHAAWNLATESPALLFSEQPQFMVKSKDGGPMWLLLCRHFTNDTLESAGLKDSTSLGKTGRLLPGYIGFYIYENNGVRVFEREGYCERSEIVSSPQTLLRFEARPNVSYAVVAFCEDSLSANYPFTLSAFGNSPIELERAFNKFVVNARVSSCWAQGTAGGSARSPTFGSNPQFRLVVRHAGSLVITLQEPSNAHNINVRLVHGKGKRIFVIRKRDVIGDSGDYTNSTAIAHVADVDPGTYTVIASTFEPDKYADFFLSVDSTVPIDLSELPRDGAGRVCRRLARATFNFGDNKVAAPLVPRRMIGVGVVASFCPGGASSLGGVRSTASESNVGSQAASNADGASNAGIRSPVRITIDVGRGSGRKILLASNNGEFTDEDGALRTDEVTLESRMLQANDMWLVLERLSGSSAASQEVYNVELRLDRETGLDVGAWRSWRDPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6D1</accession>
    <name>A0A6A6P6D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_192594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6D1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="433" mass="48121" checksum="28F0981741B65409" modified="2020-06-17" version="1">MPDMPAENSRLDGHRKRKSRHVDVEKEEKRHECQHRKGLSYEMVESHNEHSGHENSHVRLTGGEAGGEGTDGDDEATRRERKRAKKEAKKARKEAKELRKKESRKMRDGGHGGADGLPSPGVEAHREGTDGFQNIGGDSGQVWEGDKGDADAKIARREGDYAGGAEPNKANKQLAASGGGNGGSDSDGLAKKKAKKEKRKSKDTSGMDKDEHKNRSGDRKARKEHSKRRKSDASLSDGGVPARKKKARLEKAPDAINEEKKHRKQAEVETLAADADDDGMVLNIQWDVTGSQGEDQSGDDSIQRKTEETSSPVQTKDKPKRTRDKQSKGSKKSDIFVDDGPDDDLWKKGQEERVGNEADDVSLPLWKRVIAMSPKLEIPHWSTWDPQPETEADKKRKEAGKPPKGRKFKYMKSQDIEELIKVRARQLLDGDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6G2</accession>
    <name>A0A6A6P6G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_362135</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX20 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6G2"/>
    <dbReference type="OrthoDB" id="14603at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="27296" checksum="FEFED191E2234F48" modified="2020-06-17" version="1">MSTDAEKGYKPPTSADYTPPASTIDTTKKRWHPKEDLPAPYQQAPSPQPRGVPAPPNISVPTTASSSPSPSSPPRPPPSSLNDVDLHDPAANPHSLNTAGAPAQREARAPDVGVWAVVRRLSWEDFKNVGRLPCARDAFLTGIGGAFAAGGAALVLKKPLWNSCNWAVGTYAVTAMSSYQYCAVQRQREKAGVKHVVEIMRQKEGSKARAEAARKKADEEAAAVAREADEARRRREEEERAAARRAWWKVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T3</accession>
    <name>A0A6A6P6T3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_300356</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T3"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF103">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSIDASE MNL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="39"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="468"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="731"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="738"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="533"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="675"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="821"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="907"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="628"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="919" mass="100612" checksum="B3D9BDC79FE30744" modified="2020-06-17" version="1">MLRYRRYRVFVVLAVLTILALYQFGGSYSTNWQQAASSLSHLHDSDADADAKPPAAADQQQPEQQAPPALDKIEIPEAEGHVEPTATPPPVPPGDVPPQRIPPPLPSARPSPPALGDTSDGPAEPLDPVAAEVPAPAPPMAEAGEGRVEVDRPPTTLPVIHWERPTEHFPVESTVPLPTATPRRDIPRIQHDFAGQRAASAADDEIRLQRLAAVKDAFEHAWGGYREKAWMADEISPVSGGQRNPFAGWGATLVDSLDSLWMMGLVEEFDHAVEEGVAKIDFTTSIRGDIPLFETTIRYLGGLLGAYDISGGRHRVLLDKAVELAEIVMGAFDTPNRMPITYYYWKPAFTSQPHRASTGVVLAELGSLSIEFTRLAQLTKEPKYYDAIARITDALEEWQMDTRIPGLWPTKLDASGCQKHMNQIVSQSPRDATEELLGANATMLDADVTSPQQPHGWEKRQMDDLPKAGAQANANGNSGAQPATNNIPTPPDALGQPGSAQEQGNRQPNCIPQGLGHVSQTASEAYSIGGMADSTYEYLPKQWLLLGGALSQYRTMYEASAEAAIEHLVYRPMLPPPEESGPGSREWDILFAGSKHVKGPASRSDGSSSSSYSPNGDRFEAEGAHLTCFAGAMFALGAKLYPDTRGAAGDMDAARRLTDGCVWAYNITATAIMPESFHVVPCESADPAAPCPWDEDLYKRYLDPNAEQRWRAYEQQLDRERERDEMASLRALTRSSPAPAPAATPAPLAPADDAEPAGPPRFPQATPPAAAAPRLPPTVPDGLQVQKPLTRDEFVEAKVRDERIPRGLTAIGGRKYILRPEAIESVFYMYRVSGDPYWREAGWDMFSAVQRHTRTEWANSAIDDVTKEAPQLLDEMESFWLAETLKYFYLLFADEDLVSLDDYVLNTEAHPFKRPDMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7J5</accession>
    <name>A0A6A6P7J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_369769</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7J5"/>
    <dbReference type="OrthoDB" id="2146at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034719">
        <property type="term" value="C:SMN-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000019">
        <property type="entry name" value="Small nuclear ribonucleoprotein G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="3"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="9539" checksum="500D31317976EEF9" modified="2020-06-17" version="1">MPQAQPELKKYLDKRLFIQLNGQRKVIGVLRGYDVFLNIVLDEAVEEKPSNEKVRLGMVVIRGNSVVMLEALERIETDQRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7N1</accession>
    <name>A0A6A6P7N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_369905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7N1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="37787" checksum="0BCB858A71C029B9" modified="2020-06-17" version="1">MAPELMNLPLELRQMIWDFLLVDAEEHCKATIAGRRRLVLRFWGSLVDTIVRTRSDLLLVNKRVAVEILERLFKRHTPTFDSGPQILHVILRRLPSPILEWIRSVELKWCRFPPEPDYDHLDITEVRPLMDFIGRRTSIRTITVTLELHSSQRRPNDISIDRNYYWCMVIAYAMQLVLVGLLDEVCVQYTPDSVWALLEPEDDIQSMVHQKPSQWASPPESALSFLVEQLETRGIAGAGTNYSLDNIVARMGLQEWHQSNGVLEDAKEFWFVLKAPQEHDVYKQDGFWCSRDGQQFYYFPLGDWRPAATDKQPQNKGYDWVESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7N6</accession>
    <name>A0A6A6P7N6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7N6"/>
    <dbReference type="OrthoDB" id="204377at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="1">
        <location>
            <begin position="17"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="35824" checksum="BAA413B883973516" modified="2020-06-17" version="1">MGESYHGADRLDRIGYLFGHPISHSMSPLLHRTVYEALHLNWAQIPLESTDMDLFLRLIDGHGEKFYGASVTMPHKVAIMKHCDELTDEARDVGACNTLFIRDDPELKRRILVGTNTDVIGIRDAFYENVAYPEKVFHDRPALVVGGGGAARSAIYALRTWLHSSHIYIVNRDEREVATVLTECARAGYGAALSHVSSVKEAEALPAPGAIISCIPDIAPRTEPERITRRIVQVILSKPQKGAILEMCYHPNPFTTTARLAKTAGWQVILGTEALIWQGLEQDRFWTGRDVHELPVKAVHAAIEKELARHQEKELDSVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U6</accession>
    <name>A0A6A6P7U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation repressor/antiviral protein Ski3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_338409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421075at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039226">
        <property type="entry name" value="Ski3/TTC37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040962">
        <property type="entry name" value="TPR_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704">
        <property type="entry name" value="SUPERKILLER 3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704:SF7">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18833">
        <property type="entry name" value="TPR_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="454"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="650"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1001"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1442" mass="160927" checksum="D9C2EC27A3B0F2DA" modified="2020-06-17" version="1">MSVKASLKAAKAALDAKNYDETISQAEKVLTADAENYFACLFLGRALDQKGRQDEAANAYERATKIKPDDDQAWQGLRSVYEKQGAKNVSKYVFVSMRLAEIFAEKEDLHRCQVAVDNLLSFASNHGTRTDQKRALEFQLPSSPIFSFLEGRLPNPSYTYIKVADIIETEEKEKINREIGNRRTRIGARVTQVTTEVKREVILDSPLEKIYQSIIDWTPDDDVRIQYSEKLLQRFYDTLVLTPLHQKGSVKDGQERSARDNLLDAVKGAVILKRPFELAWKICLEWQDAESFAEWSPYDIQTYLSLFSESGLAKVLRGYLGTELSPFPKLLDQMKEEVSEGKTDVNKDDSLSNADRLLLMTDGLEAAKESPLAHRLMANYYLHLEEYDSAANVGRQGVQLLAGEAHKSGLDFQHSKDAMNSTLATALIYHQSPKNHPEAKSIFESILKRKSTFSAALIGIGLILEQEQEFPKALDFLTRALARDPENSRVAAEAAWCKSLNGQYAEALDELQDALARMDPADSTTRDLRSQTHYRIGQTMWKLDPSRANRKDRHGPYASFLAAIKTNANFAPAYTSLGIFYEDYARDRKRSRQCFQKAFELSPAEVVAAERLARHFADRGEWDIVELLAQRVVDYGHVRPPPGSKEKGISWPYSALGVVQMNKQEYNKSVISFLSALRIDPDDYHSYVGLGESYHNSGRYNSAARSLKLAQEILSRKEQDKRPTSPMSGKPERWFTEYMLANVNREMGEYQEAIRGYRKVLLERNEEFGVSIALLQTLVEEAWRNVETGFYGRAVDSVNVAIAVATDISKFRPEAFNLWKALGDACSILSWVQRKIDILPLQEVKTLLGSGIETKELNILSEIDGIGERALAHLVPADDEGTMDAMHLGVSRCLHAALLAQKRAIFASTNEIHAQAVAWFNLGWTEYRAYTAIEQPIEESRSVKPRRKFLTASMRCFKRAIELEAGNSEFWDALGVTTTLLNPRVAQHSFIRSLHLNERSARTWTNLGTLYLQQNDLELAHTAFARGQSSDPDYAHAWLGQGLVNLLWGESKEALSHFTHAFEISDASSLVVKRQFGFSAFDHLISSPPASSLKDNITNVIQPLFALQRLYYQTPANIPARHLAALFFERVGNHDHAIEALEIVCTAVEAEYEDLELSRDLIRFAQAKSDLARNRLAVRDYAAAAEDTETALDLMSTDDGTDGFSRPSDRDTVSKVRLSARLTAGLSHYYLGDMSQAISDFRSALEESGSAPDVICMLAEVLWATGKETEKGVAREQLFGAIEQHSTHVGAMILLGAMSALDADSETMEAVREDLHSARTQPGLDTRELRRVEVVLDAMAALSSDDPAIVKANVHNEVATSIVLAPGKPHGWAQLAAESEEPFAAQMALRTAEKSVPPHGPLSAAKLAKALAGTDCVADALRAVVLAPWLKDGWESVAERLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Z5</accession>
    <name>A0A6A6P7Z5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_361970</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Z5"/>
    <dbReference type="OrthoDB" id="4476201at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015101">
        <property type="term" value="F:organic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000046">
        <property type="entry name" value="Amino-acid permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF29">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="565"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="591" mass="63353" checksum="18048A6BBAC2AF4A" modified="2020-06-17" version="1">MSSDPPRNVSTASAGRNKSVNQEPVTSVLPGGDVPYDPNQEWDADGEVLAALGYKPEFKREFSLFTTFCVSFAILGLLPSFASTLYYGMGYAGTAVKQAHTRIQTGMTWGWLVAMIGIQCVAMSMAELCSSMPTSGGLYYAAAVLAPKGWGPFAAWITGWSNWMGQVTGAPSVNYGTAAMILAAASIMNPSYVPTNYQTFLLTVLIMLIHACMSSLPTRWIAKINSVGSTFNMLALIVVLIIIPSANNRESRGLPKFTPSSQVWGDIYEGTSFPPGVAVLMSFVSVIWTMSGYDSPFHLAEECSNANIASPRAIVLTSSVGGIFGWFLQLVVAYTVVSIDDALESPVGQPFAAYLDQILPQRISMAILALSIVAGFFMGQGCMIAASRVTFAYARDDCFPLSNIWKQVNPVTRTPVNAVWFNCGIGIICLLLIFGGELAVGALFSIGAIAMFVAFTTPIFIRTFFVGNRFRRGPWHLGRFSPYIGALASAFVALMVPILCLPTVTGDDLTPDLMNWTCLVYGGPMLFVLVWWAVSARTWFKGPKVNVEHLMLGDGGAAVVQGKDADADADADSSGAPEVVGGKAAEDLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8B4</accession>
    <name>A0A6A6P8B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase 12 kDa subunit mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_337449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8B4"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="12004" checksum="5970539786A08BF7" modified="2020-06-17" version="1">MPTPESEAFLARKPKVPPTFDGVDYDDNRALRAAQDAIIREQWVKVMMARLVREELGKCYYREGVNHLEKCGMLRERYFELLKEGKVRGYLFEQQNITPSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8P6</accession>
    <name>A0A6A6P8P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_281398</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS3/PSF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8P6"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21693">
        <property type="entry name" value="GINS_B_Psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055221">
        <property type="entry name" value="PSF3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22466">
        <property type="entry name" value="PSF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF3 N-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="87"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="20898" checksum="755CD5EA518F2510" modified="2020-06-17" version="1">MDSYYDVDAILTDSQKVPCTFELSVPGLGFLDGNMGGDMKQGTKVELPLWLAEMLAVSIGHTKLMYSHSSASAAVPSFTSLDLPSALSNRVVAALKADPRTVDLRAQAPHFYALGARILELFDEDEIVDVLSETFKVRVTTLADQAHNPRGATGEGADFLRGLDETERKLFRDAHDGAKAVRTWLAESAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P969</accession>
    <name>A0A6A6P969_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_166331</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P969"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000076">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="21"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="370" mass="40886" checksum="1A3C6486A0BDF037" modified="2020-06-17" version="1">MKFSKIFCPAGLAASAAAQADFPSTDGTLFNIDGVTDYYAGTNSYWISMTMNDNDVNLVMDHLEESGLRVLRIWGFADVNQVPGSNTVWFQSFVNGQQPQINTGANGLQRLDSIVRAAETRGVKLIINFVNFWDDYGGMQAYMNYYGGSKTDFYTNSEAQAQYRNYIEAVVSRFSDSPAIFAWELANEPRCPGCDTSVLHTWASDISAYIKSLDPDHMVTLGDEGMGLTGGDGSYPYQYTEGSDWEAALDIETLDFATFHYYPSSWGLALDGPTGQAWVENHARLCAAAGKPCLFEEYGLPNNHCDEAAWQETSAESEGMGGDLFWQLGDTLSTGQTHDDTYTIYYNSADWQCVVEAHQDRIGARTSNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9C9</accession>
    <name>A0A6A6P9C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Calcium uniporter protein, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_369485</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Highly selective calcium channel localized to the inner mitochondrial membrane, which mediates calcium uptake into the mitochondrial matrix. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates ATP production, cytoplasmic calcium signals and activation of cell death pathways. Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer, assembles in a dimer or dimers configuration with two interfaces.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCU (TC 1.A.77) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9C9"/>
    <dbReference type="OrthoDB" id="278338at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990246">
        <property type="term" value="C:uniplex complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015292">
        <property type="term" value="F:uniporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036444">
        <property type="term" value="P:calcium import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051560">
        <property type="term" value="P:mitochondrial calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006769">
        <property type="entry name" value="MCU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039055">
        <property type="entry name" value="MCU_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462:SF10">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04678">
        <property type="entry name" value="MCU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium uniporter protein C-terminal" evidence="20">
        <location>
            <begin position="397"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="66"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="215"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="549"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="215"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2460478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="578" mass="66173" checksum="D05F8C3ABC2F4EBE" modified="2020-06-17" version="1">MKLRLSTPALSRVLSVELRASCAPAPQRHAAPLFREPHPFAVPLCKPPESIPFSTWQRAQYFSTRPKLKQKSADPDRFKQLPGELNNKVTPEEKEHYERTVAESTQSGGQVRTPWQREGAEEKPVKKPRSASAMTKGKLLTTPSRMLKLVIPLTISDHNTDRKDVEPLALLVHPQQPLSYLERLIQAELPLLREGNRERVPNVWFRAEDSMRDSLEPRTPRVGREKGKGGRDDEGVQVAQEKERRDQDAEEEDTKEEREQTSVEQDEHEKMQKEHKEAVENPPHGDAAEDAQSGDVNKDRLSPQHARQLRGGPGEGGVESYSGLGHETASGRDDESSKESSEDDAEERHMVRWSSSTEIGDFIRDAARGKEFAIEIENAPSDIRVGVPSFGDRTYYLRMRLRSTSRKIAQMADVKRECDELAKKGAQRFAFSGLGVLCAWWYLVYRLTFETDLGWDVMEPVTYLVGLTTFMGGYVWFLYHNREVSYRTAMNVTISRRQSKLYEQRGFDLAKWEQLIEDGNALRREIRAVATEYDVEWDELRDEKEEKVAEALRKERDPKKDKDGDSDSHRDEGSDKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAM8</accession>
    <name>A0A6A6PAM8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL23m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_333670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAM8"/>
    <dbReference type="OrthoDB" id="275582at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059">
        <property type="entry name" value="RIBOSOMAL PROTEIN L23-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="24120" checksum="66359F09142D4A2D" modified="2020-06-17" version="1">MKPSLSLLTNNINAKPIVAPHFRFGRKPIYLPNFDVTLLRTKHLPVTQAKFQVPLFFSKLDLRDYLYNCYGVRAINIRSYVKYRRVQLGRSDRSSRHERATWIRPRPHKFMFIDMDRPFVWPDEPTDFEPWDKEQFELTNEYQQKTAGRRNSEQEPRGSDEERKTLAEQARDLLEGRQKWKPTDSAPAQASRKTEARRQRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB20</accession>
    <name>A0A6A6PB20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74545at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01709">
        <property type="entry name" value="RT_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37015">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37015:SF2">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="909"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1283"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1283"/>
            <end position="1296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1441" mass="162661" checksum="EA1BD202AC95B800" modified="2020-06-17" version="1">MANAVLSTLHHVTDRKLRKLAEHQAKFISQRALILAEAEKETEPNKKVQALLDGIKKHGLEAGRGGMSVKNVERFLNQSRYDPSVTPALMRQWENSLLHDLEIQSLKYDYAELFGKLLTEWIQNQNPAMPASAASDDDAATADADSSASGFEPIGREEMHEQRKQWETFAFTLKMTDTENIRKYLTELFATASEGKFKTGPLNEIRKMFAKLDESSPSRFDSDIVVTCIDGVLREDLFAGKKRQALVDLRSKTSTVLREMADVLNMDLDSLDTWQWEPSPVRLNMRRQLSGKYRVYMDEEIHQAIFCHFIGMKFAVYLKKGLGMLYDSPAWHEILQSELIPRHAQDRREYFLGANERRTIPGSVWHRRKSDFRDNYFLTQLPDHFDGPSMPYDDDDDIDKATNQKAKGAALLKEQMFRLATTEMLINKKVHGQFCVWQSDFKWYGPSLAHSTIYEVLRFFGVPTKWLAFFRKFLQTPLAFSHDGPDAVVQVRKCGVPMSHMLSNALSEPILFCLDYAINQRTEGGNLYRLHDDLWYWGQEDSCQTAWTALDEFANVMGLSLNEEKTGSALVLDDPGLFRSPRSPLPQGPVRWGFLILDAKHGRWIIDQKQVDQHIEELRRQLGACRSVLAWVQAWNSYVSRFFSTNFGQAANCLGRQHIDMVIETFKRVQKAVFAGNSPNEGFDANVTDFLRSEIEKRFNFKGLPDGFFYLPAELGGLELRNPFITFLARYEKAPKDPVDDVLQAFETDKTSYERAKNRFHNGDFKPDYSLRSKVLKYKAAAKEGEPVKLSAEFDPQTETFMGLDEYVRFREHTSRRMGTVYEKLLEVPEEAVVAQTPEVDRALSDLAPNSIDRSGLTRGWNKASPYWKWIVQLYAGEVIEKFAGLSMGEKDMLPIGLLEVLRSERISKASKPQQMEAHREAVSRIAATVRAFHERQQSFRIYHGSTNSTRMNKVSRDRVVDTSGLNRILSVDASRGVAVVEPNVPMDALVAATLPAGRLPPVVMEFPGITVGGGFAGTAGESSSFKYGLFDCTIGAVEMVLGDGEVVRASRTERRDLFYGAAGTCGTLGVVTLLEVDLREAGGFVELEYRTVRGVEETLKVVEAFTRDESLDFVDAIMFSAERSVVMTGVLTAAPSPSLPVQRFTRAHDPWFYMHADRLTRRQRPLSPGSPAACADALRIAIPTPDYLFRYDRGAFWGGAYAFRYFATPFNRVTRYVLDGLMRARPMYAALHASGIGDRVMAQDVAFPFSTAGSFIDWVRAELGIFPLWLCPLLPPARARARQQQQGGEAGAEGAPRPPAFYTGRDLRPDAPMLVNVGVWGMGPRDRARFVAANRAVEAAVRRAGGLKCLYAHAYYTEDEFWQIYDAEAYGGLRRKYRAEGLPSVFEKVRVRGPGEGGEEDGKRLGWVGWVKGRLWGVWPFNGLYGVWRAVVGGDYLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB63</accession>
    <name>A0A6A6PB63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amine oxidase</fullName>
            <ecNumber evidence="9">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_279635</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="9">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="8">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8 9">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB63"/>
    <dbReference type="OrthoDB" id="3341590at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015328">
        <property type="entry name" value="DUF1965"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF20">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09248">
        <property type="entry name" value="DUF1965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00766">
        <property type="entry name" value="CUDAOXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0186">Copper</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7 9" id="KW-0801">TPQ</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025404291" description="Amine oxidase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1965" evidence="12">
        <location>
            <begin position="260"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="11">
        <location>
            <begin position="340"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="7">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="8">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="797" mass="89786" checksum="7F2BC58E5261FC39" modified="2020-06-17" version="1">MHQTRFLGVFGLCGLAPTATLAAVVKPAIGLERRLLHEEIDKRGWSPNDTCVSEESAPATTAPKANIWSAITPEDNAAVWDLLHDPATGLNLTAPGDAVLTDNYVYWIDTVPVNKSDALPYIDGDGPMPPKYARAIIFEGGKEPPISQEYMVGPLPVCEETTVAPLDYIYNGGMGGAVPFNGRHFDSKRSAATEPLITEVMSSIADITVAMFNGAYYGSDDDRTNLTTTSGTPLSFDGTQAFRNIMFRYPGEPHGTASYMIPLDFYILIDCTGTDASKYFLKGIVTGEMFYPSVDEFRAAYDSGEVAFAFQQTRDDNWAMVDYKPELGERELEERFSPSSLELDGKRYKIDPEARYVEYMGWSFYVHFTRSLGIMFYDIKFKGERILYELSLQEAVAQYAGNQPKAANTVYHDTYYDLGTYMTSMVEGFDCPFGATFWDVSYYEENLKVSNPDAVCIFETDMTHPLSRHRAGGGSTDYDFQNMGVVKGSFLGVRAIATVGNYDYAFTYQFHLDGTLQVEVRASGYLQSSYYYPDQQAWGPRIYQATMGSLHDHVLTWKADFDIVDTANSLQVSELKAVNQSQPWFPELGEFEQLQLDISYMEEEKQFNWFPNQQGMYVVVNKDALNQWGEYRGYRLVPGMSDIHLSVLNSPFSLKQNEFSKSHLAISQHHDTEVFANSVQNANLPWKPQQDFSMFFDGESVEQEDIVLWFNLGMHHFTRSEDVPVTLFTEAHSSILLAPQNFFDRAQDGDLKNRRWLVPDEDTGELMVETYGIELPQCPVILEEPADALGTNTETEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBB1</accession>
    <name>A0A6A6PBB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">XAP5, circadian clock regulator-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_383908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBB1"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="193"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="382" mass="42413" checksum="FDA7D6BB40D0A6B1" modified="2020-06-17" version="1">MSNPSSADQSRTSTPNPNAAASRFTSQNTTAEDLLKSQTVGLVHLSDFRKRRAEALELKAREEQERSLGRSPGPPAPGTPGEGGATPQPVKKKRKKVPKGKLSFAFDDEEDGELAETSAAPSPRRSNTPDERKKDVSEDDTATAAPLKKRLGPNSGVTVTPKAMTKSILLREAQTREQLRKEFLVMQAAVKATEIAIPFVFYDGTNTPGGVCRMKKGEQVWLFLDKARKTGARRKVGGERSQREWARVGVDDLVLVRGEIIIPHHYDFYYFIVNKTIGFDGQLFKYSAQPTAASPVIAEEDEDAAIADPLARADKSKEKSSVKVEELEGYHDEPTLTKVVDRRWYERNKHIFPASLWEEFDPGKDYSKGIRKDPSGNAFFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC31</accession>
    <name>A0A6A6PC31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC31"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="74" mass="8754" checksum="DDDA94217C69A0F4" modified="2020-06-17" version="1">MGFVNDSVFWVHLLAVTSRASICVGLSFHYWDRHVVFMQRGRTRNVSYPHMGPNCGHSWHPYTSRRVRAMDEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC45</accession>
    <name>A0A6A6PC45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingolipid delta(4)-desaturase</fullName>
            <ecNumber evidence="8">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_313850</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:46544"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:31488"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="1.14.19.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="8"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC45"/>
    <dbReference type="OrthoDB" id="200948at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017228">
        <property type="entry name" value="Sphnglp_dlt4_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="10">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="416" mass="46046" checksum="1DBE70EC6FECC385" modified="2020-06-17" version="1">MAPPSASTTGTTVVAGANKRKDDSIRVVDGSGKPEETPVDDYDKFFWTYTEEPHRSRRMAIIKAHPEVTKLCGPEPLTKYLVLAVVSLQTLCAYLLRDVPVFSWRFLLTAYVVGATANQNLFLAIHEISHNLAFRSPEANRLLAIVANLPIGIPYSASFRPYHLTHHKSLGVDGLDTDIPTALEAFFFDSVAGKAFFCTFQIFFYALRPMFVYRVPLTRTHALNVAGQLLFDVVIVKLWGPTALVYLLVSSFLAGSLHPCAGHFIAEHYVFERGSTADAARGKAAATRDPAAASIPVPETYSYYGPLNWLTYNVGLHNEHHDFPAVPWSRLHRVNRLAAEFYDGLPCHRSWVGVLWQFVWDRDVGLWCRVKRSEGGRKVGGGSKVEGGKAEGGEVSGGWKEEELGANEDKVIPGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCY0</accession>
    <name>A0A6A6PCY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I 3-dehydroquinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCY0"/>
    <dbReference type="OrthoDB" id="197068at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000135">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050068">
        <property type="entry name" value="MurA_subfamily"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01093">
        <property type="entry name" value="aroD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43783">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43783:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="642"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="725" mass="78464" checksum="CA8EA12F933469C2" modified="2020-06-17" version="1">MLQAEAPATPTRLKRAVVEQVQELPFNGAANRDKPALLIVHSEGEVGIVGVFADVLGQPWRSVETPGEVRMEPDPTTVLGIGAAAYGLGGRRQRWRRRIVINAHCVDAEGAAPPDEALTARCDYEYLYTRRPFFRRDLARFLSFILGQTDHHRDLSRKKRTTLISTTFPDVHAALPNLDILSVGADAIELRVDLLKEPLGDGTYSALPSLRYVGEQLMILRQRTELPIIYTTRCTNENGRFPMDDPGLFYRYLYRAIQWGVEYIDVEVWLPEEVRRSLAERKGSSRIISAFHDFSGTFKWTAPEAQALFEKGAQYGDVVKMIALVNSNDANYELEYFRSIIQAKYPSPPFSGLNMGLQGQLSRLLNKIFTPITHPLLPMIAAPGQLSAAQINTALHSMGQMPKLDIYGVGSYRSTTQAMFFEKCFNELSLPHQFIFVEKGPKGSVENLIRRHEFGGAYVNPPVAVASAPYLPCLSDAARAIGQVDTVLAQRAGGGGEAGAHNAVVAAANAPTAATFVGDNASWKGIRATLLRDFVPTAYGGRAAFVLANAEADAAAAIFALKSLGIGPIYAIGFRGQGYLAGEVEPVRSVEDVKRLEQPFVIISALPAEKSPLVGPLLKHYSGDGNGNGNGNGNGAAGGRRSGTATPTATAQPEAPGTPAGNKVFVDLSNGPRKSDPLVTATALGWKAYGIADVSAWTTVETLRLLVGQNVPYDFVRLASGRGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDI1</accession>
    <name>A0A6A6PDI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_329708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDI1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="30763" checksum="F6380110B19F850D" modified="2020-06-17" version="1">MMGGKNSVGGAVQVRWLLLLLALLLRLLWWWGGTEDSVVHSDGPALAIGTDTLTMESGCVGAERVRRNVGRQRPRRVWMVLLRLVLLFVLLSIAIALLLLLSALFLLPARRWWYSPRWALSIAASTTGVRPRRASSASRTMVALLLLALALLIFPELAHQGIIDVVDRVCALRTSKLKLPEWICGRVGHTCSRKALCWGLRRSAERIWRGTVRQSGGRRGGRRGARRRCGLVTGRVPRVWVVQFSENEVKALSTGLPQCVPSKDVQECVGFARKHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDS4</accession>
    <name>A0A6A6PDS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Translation initiation factor eIF2B subunit gamma</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_5240</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDS4"/>
    <dbReference type="OrthoDB" id="10250549at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="14">
        <location>
            <begin position="12"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="EIF2B subunit epsilon/gamma LbH" evidence="15">
        <location>
            <begin position="412"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="550" mass="59105" checksum="9E74723FAAD03486" modified="2020-06-17" version="1">MPRAISGPGFQAVILCGPGVSLNTFTSKMPKALVPIANRPMVWYPLDWCYRMGISDITLITPPESAPALEAALSQNPHLTSLPAPKPEVLSPPLLTPTTGTGELFRLPEVQSAITGDFIVLPCDLVCELEGTALLEAWMIQTAGLGGATGGLTETNKPAPMTLGGEKSGRRGGMAVWYHTKGEGSVKGEETDFVATTPLPPPIVPSPRGSIRPQVSNLVYSLPTDTLNDVTAEKKGFPIRQALIRRHGRVRMRTTHRDAHIYVFPHWVLRLMKRNALDSVSEDVVGLWAKATWQHPRLAEKLGMREIFADAADKEPDDAMGGSGILDDEVDVAALSSTYEPRTENKVGSFSVPPMLAYVQPPGPSLPLIRRVDTAALLLSVSLRLARLPSLEEGSSSPLSHTAKTANPSGVPKKCRVESADSLLAENVTVAEKCNIKESVIGANCEIGEGARLLRCLLMDGAVVGSNCQLTGCILGRRCKVEGGPARDEKTVLKDCEVQEGNIVPWGTEAKNEKFMIFEGLSDEGDVEEDMAEHFDDVLADSGEPGVSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE50</accession>
    <name>A0A6A6PE50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP cyclohydrolase II</fullName>
            <ecNumber evidence="3">3.5.4.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_330489</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.25" evidence="3"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE50"/>
    <dbReference type="OrthoDB" id="5569761at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001591">
        <property type="entry name" value="PRK00393.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF29">
        <property type="entry name" value="GTP CYCLOHYDROLASE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="10">
        <location>
            <begin position="258"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2462110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="440" mass="47321" checksum="F043B125E44460C9" modified="2020-06-17" version="1">MTASSSTADGSLPAHASPAFPPLYSPPNSRPQQLDEYGVSDLQLNGARAKSPNHDTFAAPTSAPYNTATTHALSTSSLPADSSAAADAESRPPPPPSLLSPAVTPPVTPGETTSAHTNLLHPSPSAPSDTTAELPHQHSLRQRRPSKPRPRLLETLPEVNCVVRARIPTTTGQEMFLHLYTNNVDGKEHLAIVFGGNIRSRSLDAERPGETELDRMIRGAYVGTLYPGRTSSRTGEGSSAAVGQRQQQGEYDDDAAQAVREQEVQERQAPLVRIHSECYTGETVWSARCDCGEQLDEAARLMSLPSAASSGGVIVYLRQEGRGIGLSEKLKAYNLQDLGSDTYEANLLLRHPADARSYGLATAMLLDLGLGGDQGIRLLTNNPDKVSAVEGPNREVVVKERVPMVPLAWRTGGKEGIKSQEVERYLSTKIEKFKHMLNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE62</accession>
    <name>A0A6A6PE62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosyl-DNA phosphodiesterase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_330506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE62"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="498"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="3">
        <location>
            <position position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2462120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="545" mass="61841" checksum="700964FB700190F5" modified="2020-06-17" version="1">MDRAYFGQSTTGGHSSHALSQGGPPVEENYVHLGPGVQNHFWSGALKRTWIYNFQRLGDDIRLEEVLKARDLETAYLCSYEFDAPWLFSKLELSRTKLFLVMHADNEQKHFYRQECKSLGLDVTPIFPPARSGNMTSMHSKLMILKYIGSVRIVVPTGNLQPADWGETGHMENMVFIIDLPRNEAMAPPTPVEHLPIFGQELLRFVDALGLDSSAQNMLRRHNWHNTRPFGFVHSIPGTHNGTNMYKTGMPLLNNLVQQLGLGAYDNQRILSSWVDYMTSSLGRLKEDYVANFYRALQGEFDASNQPRTGRKMTKPEREYRKKLHERFHIVYPCNKTVQESIGGSGGAGTICLAHDYWIDDDFPKKLMHDLKSVRRGVLNHAKMILVRTHVSTGLSVHEFTMKCWAFVGSHNFSESAWGKTQRMRGSDDENRHKLIVRNYECGVIVPVGPDTIASYTWPALGEDEFVILEDEVPGYDIFLGSIPIPAAMPPERYNRYNQPGGRVTSRKVPFTFNPEQNPTTDVVPVDNETEAESSEEDGEEDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF69</accession>
    <name>A0A6A6PF69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication factor C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_14667</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF69"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000012">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000007">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000107">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="62"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="354" mass="38979" checksum="9F6BD61B889DEA95" modified="2020-06-17" version="1">MVQPEQGESSSAARNGSKASANGSATNFELPWVEKYRPVYLDDVVGNTETIARLKIIAKDGNMPHMIISGMPGIGKTTSILCLARQMLGGAAYKEAVLELNASDERGIDVVRNRIKAFAQKKVTLPPGRHKLVILDEADSMTAGAQQALRRTMEIYSATTRFAFACNQSNKIIEALQSRCAILRYARLTDAQLVRRLRHICEAERVDVTDDGMAALVFSAEGDMRQAVNNLQSTAAGFGIVNGDNVFKVVDSPHPVKVQAMVRACYEGKVEVALETLQELWDLGYSSHDIISTMFRVTKSMDSLSEHSKLEFIREIGFTHMRILEGVQTLLQLSGCVARLCKINMKPDAFVLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PGH9</accession>
    <name>A0A6A6PGH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FDF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_331431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PGH9"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="289"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="321"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="464" mass="46814" checksum="87690FCF4C9EE296" modified="2020-06-17" version="1">MPPYGAPPGWYPPPGQGFPPGPFSPPQPGQMPPPIGPPGQQQQPQPQGPQQQQPPPPIGPSGAKDLAAKPPQKVEADSTAAKPDAAKPSSKAGTPVPSGPAAGAKQPPPPPVESKPDVSAALAPATTTTGSATSTAAQTTSPQPSAATGKAPPTGPKNNRIVPAIPLGSNNQQPRQAPVAPLQSASANVPPKMTAASASQPVAAQAAALNYQNATQAATAAVAAAMAKLPPAPGQKAGAAEGSAMDNLTKKVAEMRADDRIRHGNKPGTGGFAHPRGGAQHRGRGAARGGMNKVEVPTTDYDFESANAKFNKQDLVKEAIATGSPLGDSAAAPNGSPAGGEASPTNGTDGEKTAGTHPDVVIPTDKPATYNKATSFFDNISSEMRDREEATSRRGAEFRSEERRKNMETFGQGSVDGYRQGYRGRGRGRGGGYRGGRGYGGRGRGGPTRGRGGMQQAGAANGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKQ9</accession>
    <name>A0A6A6NKQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_257958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001735">
        <property type="protein sequence ID" value="KAF2452236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKQ9"/>
    <dbReference type="OrthoDB" id="4357141at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="231" mass="25690" checksum="DB08B76B72C77FC1" modified="2020-06-17" version="1" fragment="single">RNILAGWRGSGLFPFNPHRVLADILKPPTQQTILKAKEIMVDTCPHYTELPTPATPVSGEALTSLLDMIKHVPNDEASSQHKERLQKKVSNAAQTFLAKNALLRDQNRFLTKMNDEGKARRAAKSAILGKAKVMTWDDLEKARAEHIVKEAAKTEKKAKKTAKEAKKIAKTTLQAEDAATKERKRGRKRMAATAGADPSEPMAKVARIIDGQVDKNEVITEPWRAPVARMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKR7</accession>
    <name>A0A6A6NKR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hh protein intein-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_367853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKR7"/>
    <dbReference type="OrthoDB" id="3941414at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039510">
        <property type="entry name" value="Vint_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032838">
        <property type="entry name" value="Vwaint_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14623">
        <property type="entry name" value="Vint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14624">
        <property type="entry name" value="Vwaint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWA-Hint protein Vwaint" evidence="2">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Vint" evidence="1">
        <location>
            <begin position="354"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="445" mass="49094" checksum="7617E4F1AC90C575" modified="2020-06-17" version="1">MPIPNSEKKEKSARPQIDCKISIYQVEDDGLIVKVVPPTKPLMNQSRGPVEIVLLIDVSGSMNDLAPVPPSSEGEESEQKGLTVLDLTRHVACTIAESLNEHDTLCIVTFSTDCASMLGTVFNYAVANLKSTYAQKHFLARLPANKFLDDPLNLGLIQDLIGAENKKGEVELALRTVVEPKKVKSSWEKWGCHYLSSFLMAHQFQKCFSFKDPGTQRYGKSSQLFRDQLDVLDNLFDSLPAPPPSRPPVPLSYGTVTGGRTAPLSPPSDMRQYRNVKSTCFTRHTRVLVVDPDDSTEKTIPIEKLRTGDIVKTLKGNTRAVRTVLKCHTDQTKGRTMTVIPVNDTTNLWLEHQAGDVANDHAINVEGLWGATMGHGLTPKSAAGKVDVRIHDFYGDWDAVAKSLDKLPKHDGLALGDGTTKDKATVLFPEEKANEQPQLQLDYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL63</accession>
    <name>A0A6A6NL63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_329217</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL63"/>
    <dbReference type="OrthoDB" id="6130531at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="6">
        <location>
            <begin position="286"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="366"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="225"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="320"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="601"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="764"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="609"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="649"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="788"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="805" mass="89294" checksum="3ED303F07E445552" modified="2020-06-17" version="1">MTPSIDSTTSATSSSNHGSSSRASKASTAIAFAHQAERLGQYTSSQEPAASAGASTQAVEAKFITPQDPVIETASGGRLPAVPLAEAQKLNALKDDIEGCRDPSVHGPKHANVVRQAKDGTLHGVSPESAESSHQSTEPGAPLRLAVPPSRTNPLFPPLPMYGPPTLLRTLQCWSFRASSAVLSLCFLLVIMLGAIFTSIGPAIGNAWLRVTFRDPRKLRPFYEEEERRRRERRREEREWNRKKGKAAGQQRGKGKRKVKSEAVSSDEDEFVPTEGGPDKLLCDVGYYARRVGLDCESYSVQTEDGFIIDLWHIYDPRRERPAPKDKRRERSPEVFIEHDDAEGRRNSTRAQRSGGGSASKAKRKYPVLLIHGLLQSAGAYCTNDDDSLAFYLAKAGYDVWLGNNRCGFRPRHSLLSYNDPRMWAWNIRQMGVLDLPALVSRVLAETGFPKLALVAHSQGTTQTLVALAKEQRPDLGEKISVFCALAPAAYAGPLIGKMYFKFMRVISPGMFRALFGIHAFIPFMMRMHGTLPAKFYGEMGYRIFSFLFNWTDDRWERDLRARMFRFAPVYVSAESMRWWLGRECFAKQKCILATRQEARIEDAEDREEDRGAAGASDREERYFDEGETHPSEGTPTRTLQPPANGDVTGEGSGGGGNGNGGGKADDDRGRFAWYDARAPPMAFWVCGADGLVDGRRLLRRFERGREPFVDVVHAKIIEGYEHLDVLWAVDAVDKVGREIKEVVWRTAPEEVRGSVRVPKGCEEVDMGRGMGGGKGEVRVGLDTGAGEWREEVKRTSEVSGESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM52</accession>
    <name>A0A6A6NM52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_358283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM52"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="6491" checksum="F408CAB99D124165" modified="2020-06-17" version="1">MPAASCLSKLRRVKKRNDAGIISNTDHVPRTPGVRGPPILTPHLPKYPNDTLNRERHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM78</accession>
    <name>A0A6A6NM78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_294054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM78"/>
    <dbReference type="OrthoDB" id="5015991at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="13715" checksum="29D8E65E86951EDB" modified="2020-06-17" version="1">MCFFDQHRFSCGDWKWGHFRQHCNREYRIGETCGMKLVMTTFDVKQRCKLCEKIETKMRRRAAEMERINRWQHESNRSASIERSMEIVRQLDQEIYDLSCERSRRLHGIGSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMN1</accession>
    <name>A0A6A6NMN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ataxin-10 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Copper transport protein 86</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_150821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a role in the regulation of cytokinesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMN1"/>
    <dbReference type="OrthoDB" id="379794at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="8">
        <location>
            <begin position="931"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="485"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="831"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1002"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="485"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="533"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="850"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="884"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="913"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1066"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1078" mass="118955" checksum="5597BED431F1EB15" modified="2020-06-17" version="1">MAAPTEGAQREPPQPHKGLGFDYSVLMRIAVAAYIAHFKLAGSIKEPDLKKLDGYVRRTLGQTVRNPDVRRLGLCEPLWVLVFEAISAAIPSLTSRCFVRAANLPRRNPGEDPANAGASSVAHTTASALPGAQDTVSGPLIISNMTSLLADLERLIDLLGVARNALACGDGELTERAQKYAADADVHRAVCRLISICVRVAARGFENGSGAGAAAAATVDGQPVGPNPADEEKWQIIVSKYKLALVTGLQLLNNLVSKNERKKLMLWVELFDSSCGTIFPNGSTDAPTKQKGRPPSFDPKQIETGFLRSDLDKAALDETAAIQNLVDEGSPKTDGVKRNGNPSPFLQFMSTVGQSIRKELADNGGGQGCGTNVAEKVVTALELVTECRRRWQAMSEEQRAEWTMAAERGTEWTFAGPLNDRSEDLSPAERFAITTQAVIEGQKKSIPHLYGNSSDEPIPPAKEDFRVTYSSEYGASILRRGKEDLLDRLEPLEPRDQIKPTQSEKASEGEKDSTRDASVVVETEQTLPQQRSDEDDYGTESEGDDEEDDYIHSGDDGRGLLTDVPLILGPAEIEVLPVLIMGGIFRNPSSETSHPSRQQLDEQDPLSRIGENLYRVRCHLLLAQENGRNLLRELLIFVAAWDLREEELYFRVMIKIMEAILDNGLMPFAYHAFRENKDIISPAQAVIMKLLANIFRSRQLADGEARDTVTTSAAKDFNSPPEPTPLGFYPSRVDVRMASFLFTEFRQRIVPQTCALIFLQGRVHARRADPQEFPLNLWDMERMYEGLYQYLEFFAVLTEHPVWKDMMADWDLCSEIVTLLKELDSAIPKASAMSASTRQQQQGREVQVPLPSPSPPPPPPPPPAQASSQPPPVAVERPYDLTEPPISQASSQPAPSGDKSNQFSPSGVADVDPWTDEPQDEPADFEWRNLKKLAVLVLSSLAWKSKKVQDQVRDHKGIEVVLRCCAHDEFNPYMREHAVMCLRFLIEGNRANIELVSALKDRAKGKTSPTTDRVAGDVRGSSDERDSGARSLPEVPPEVLDQHGYETYVDDEGHIALKRRDKRTTPTHLSTSPATQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNL9</accession>
    <name>A0A6A6NNL9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_388293</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNL9"/>
    <dbReference type="OrthoDB" id="5584477at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="391"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="471"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="771" mass="87325" checksum="C8B44E82AB4F3DA4" modified="2020-06-17" version="1">MAALSDAEIIAQNPIGGQLDSFRRALQSTFDELRLSEVKDHRSLSARLVETTDAKFLAVDLVLTLQTTSLARTLLSRSGTGTLLRDLSGLVAHLDSPDFDTRSFIPLFEHVDGCASDQEICAALFTLLASLRSTPPTVFSKLPLDTPVKSNSSSQCADEQTHNDIDERILQEINGCVYRDTKEWSADADRMTKMANPQVRSGLWTEYPIVPSQDAFFSWFWAFQRRYLCRGRGTFYASPDLPLAGSDYVRKHTDELLKFTGHAREVFAAQPTRRFLHGFIIRGSIMELWVFDRSGLYGSEKFDIHKDPRRFIKIMFGYTRMSDEQLGVDTFIKEDKEGKYVVLEEEAKEEHVYLEDKPIAFQRAIVCRGTACYRARKRGSQQWQYVVKFAWRSNKRQAEGELLRLAKERNVWGVAKLINHRDLDAIADLRSGLQFGKPQIFRLARQNLISQSRTGTRSSMLANPLGISLTPLASSSSGQKRKRADEKAMAPPPKWSRSKSSRRSHTTGSSVQADGGVSSCVDDNPNLNSLTTTPEVGEHGSFENRIFSCLIISPPGRPLREFKSILEFLHVCLDVVKALRSLHCNGKILHRDISENNIIIAETKREEEPRAIVIDLDLGKELDRAPSGARHRTGTMEFMAIEVLRGKQHTYRHDVESFFYVIVWVIISHRPGGSQGLSKESQLRDWYRGSYTHIATIKRGQMDRGGFKDILAEFLPAFESLKGPVEELRDILFPYRGELFTGTYKDPDRLYHPMIKVFERAIAQHRGLGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP00</accession>
    <name>A0A6A6NP00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_403828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP00"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF31">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="11"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="404" mass="42988" checksum="3EBB1EAE8F877993" modified="2020-06-17" version="1">MASSDTDTVTFNASCLCRSSTFTLTWPRSSLPIPVRMCHCELCRRTHGTLCLFHATSPPPSSTANMCTYKTSPSETRYFCATCGSKMIDHSSSGAAGATKAGGGDGHGDGGRWSVSIAVLDAPEETWKYSEHIFVCSTLDGGFADWLVRVPGDPDDLPRCAMRDDSRLVPLGWRLGPLPGPGEKKTAKDGGEAERLRAHCMCDGVDFYIGRPGDKRGDEGEDPLAALPPSLRAADQSRFAGSLDACMSCRVAAGDPINAWVFVPLALMSAAASAAAAPQPYLLPLPDPAAIPSLGAAAPPTTQPTSPALKWFASSPDVRRFFCGTCGASVAYWVADRPGVVDVCAGLLEARSGARAEEWVEWDVGRKPFDSQSAILKRLVKGVEEWGKKWAAERGMKVVEEAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPD4</accession>
    <name>A0A6A6NPD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPD4"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF143">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="466" mass="51695" checksum="D8C51A9E0781D46C" modified="2020-06-17" version="1">MGQGGHINLINGSPYDWTSTGSHQYQMSGWEWPDTVRSGSSVQAYVEWDQDPGVHDEDDAGEAYYSITGSPDKFSVHANNRDGFEIVVNLDNFETKNNPRGSTIDVGFEWGFTRNFILSGSAGDYSSSNPPVDWMHQNLETLGDRKLRHICMPGSHDSGMSVLGTKTTGASERNTITQVLNIYDQLKAGARFFDIRPVISNGLFYTGHYSEIEGFWQGGNGQSIDEVIDQINRFTSEYKELVVLDLSHAYNTDNGATSYTDFTQDEWNRLFMQMKAINGRLVDAVAGNEDLTQWTLNNFIGNGDGAVLIFAEMAGGASVDPFKEEGFFSPNNFPVFNQYANTHDVDRMRSDQVSKLKSNRDIVPGGKDGFFLLSWTLTMEDVGDILNPAVSILGFSSKCYYPLFEVFNSFRPQSFPNVIYVDGFGVQLPGNYLFDDFHGNPRPSTDITALAMAVNGIAGKNTYITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPK7</accession>
    <name>A0A6A6NPK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mis12-Mtw1 protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_327393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPK7"/>
    <dbReference type="OrthoDB" id="3364649at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="527" mass="58078" checksum="F87C00912F8ACF3C" modified="2020-06-17" version="1">MTAVIRREPLQTLNMSSTQRPARRRSARLAFEDDDAPPVKKAKTDATKTSDAGGGKANGARSKKQKISYDEDDDGFQFSRAKSKRTKTKQPQVPEPIQEEQASTASAPKKSTRRQKEPALTAPPAQQDEGEGPTTRRRSARLSGDNIQKTPPPEPTKKRTGKKGASKDFRDDDEVNGIKVIDDALQVEKVRSPTKIALPFADTPVIKRNKEMRKGSGKDGRRRSSTGLRGRRASSLIDSGTSNAVPHSEVETQNFYKHIEQSLPEPRRMKQLLSWCGTRALPEKPSGHVPDSNAIMAARAIQQELLDDFSNKSEMSNWFDREEQDDAANEPLVKQPNPRNVQNAQKLQELEEEVKRLQEEKRSWDTLLKDSSAALSQSSKAKAKASPGEDSERKITQIDASLLDDPAQVEILSSLAESLSFAQAPSLSQAPPSGTSSLIPQYVAEIQSRVRHVTSTLEPTVDIFADGIHKLSQYRLAADRVADRILGSAVQQLEERDRAAKERAGTEGIGTKEVLRALSGALADKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU9</accession>
    <name>A0A6A6NPU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_117999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU9"/>
    <dbReference type="OrthoDB" id="340550at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42106:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42106">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="715" mass="74622" checksum="60CFF8E8F5F9F1F0" modified="2020-06-17" version="1">MSMDESTLPGRDTTAPKSDSDRADPGDNSATLNATSIFAAAAAARTPSKSPSKSRSLSDSTPTLSPSPKFREPARLSKDDHTIVSSSSGTPGLPRIPRRPDFLARGLSLQMPPRESTPTSLLTGSRGAPLSPQLDAHTTYATPATVLPRHSRGLDFARACTNLHHSTLAEQSSPDSSPTVTQKGSGGGMMIPQRRNHRNSASMMDSPAGGIGVWSMGGGDKMTVASSSLGSVNMLGSDSDSSSSDNDDIMESYEPDDPIVNTPQVLKLNNAAFPSPFGLPSLSSPSGGWTGSGSPAAPTASLMNYQRARLRKAKSRHSSSSASAHSSMASPGPGSPPQGKSYEGNSGGYFAREVVKRNAGSRRESLSMVTNDLHISSGNDSGDELRAPGVVRRPVTRRGNLLPKTRAFGRIRAELLEESAPIDSEVKREAEVIRQVRESDPDDRPQSSTANSSPSLLPAVPGANEVLEDIPEDGAMGLDSESGTGAKGLFGAFSLQASKNRAGPSFWNRFDTQMQTPPPPTFPRGEPSATGEDVSMDSPSVSSSSMTTGGIFNQLAQNGNNGPNDSSMKGPSTEPSRASTPQPNGSSNPFSSASSASAARPSAVEGIRKANKRRRDDDFDISSIKRRAVSPSISVQNSPILSQSPGQRESIWSQATKRESTVSASSGGGHAAGERSNSGASSVSTNVTTPALGPKRVGMQGMTDTNDGLMKMTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPY2</accession>
    <name>A0A6A6NPY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein SLX9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_125439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPY2"/>
    <dbReference type="OrthoDB" id="5429132at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="20648" checksum="D7B42874F93A8783" modified="2020-06-17" version="1">MAPIPPRKSNPKSSSRTAESSRPRTTYPAPTTTFTTTKKDKRAMKRSILLNKIEKSYAQPAKKRRRPSKKLVANLESLTEALPDVGEDDRDNGDGEAVVGQARIRHRSLKSRPGAMKRKEKLERMERERFDRNMAQMLGGGAQQPPGGMETDAGAGAAEGSRSALRFSALRSFIEGTMEKKEFKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPY3</accession>
    <name>A0A6A6NPY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_310018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPY3"/>
    <dbReference type="OrthoDB" id="70387at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="481" mass="53090" checksum="C899481011B9330D" modified="2020-06-17" version="1">MLHGLVDNLVLELLRGWDVSKKVLLIPGMSGAEWENPMTKKQLSKIRRKWNWIRVLPPLLWGFDEEAAAAAAAATSGGGGRVVAPWGGTLELVESVRNLIDLMTIGQDMDHLAMRQPPGCFPAAAYGKFAAPGSKSLPPEIWTIILDFTGDWELAKTLHVYTTLPVPPEWQQQFLAVMNPNTITPSFMGSLEWAILAGSLATVRELLSNNPAPRWLSTLCVKLIMRFGRVDVLAYLEGAHKDLFWATFGHAFLPDKASAVFGRAEILEYWRTSPAFLTKEYTAEALDGASKAGFVHVLDWWHRSGLPLKYTEAALEQASSKGHVDVLEWWKAASMHDGDTGGGGPAPGKSVSYATQSGLLPVLRWWGTSGIAFPHEDTVAKLASTHGHVALLGLWHALRGEKVIFDNQVLVGATKMGHRDVLEWWRRSGLRVEYKTCDIEEALEDGVGGRKGDEVRKWWARNGLNLGVGTSEWMRTKVLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQD6</accession>
    <name>A0A6A6NQD6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_366660</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1108038at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16702">
        <property type="entry name" value="RING_CH-C4HC3_MARCH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000287">
        <property type="entry name" value="RING finger membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056521">
        <property type="entry name" value="MARCHF6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCHF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145">
        <property type="entry name" value="SSM4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23113">
        <property type="entry name" value="MARCHF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="766"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="794"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="824"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="998"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1092"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1154"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1197"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1357"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1395"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1452"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1550"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1607"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="17">
        <location>
            <begin position="33"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="41"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="316"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="439"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="444"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="594"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2453951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1675" mass="184924" checksum="348F8B89277094D8" modified="2020-06-17" version="1">MAAPSAARSSRGGGRHRDLMNDPEYATNTEGAKAPEDPDTCRICRGEGTAEEPLFYPCRCSGSIKFVHQECLMEWLSHSQKKYCELCKTSFRFTKLYSPNMPQRLPLSVFLRRAAVHTVQTVLKWCRWVLVAFVWLCWLPWCMRFVWRGLFWLADAGWARDASFMQSPLSTVDAELASRGNSTYNATEVPSQAELSLFGGPALRLSVNTSEPYVFSLFRRYSFLFHARPLVPTSGYDASDLQNSTASATLQGSSLLSDMSFLRNLTSSPAINRLLMDVVEGQIITVLVQQPVLNLAPLNGENQELRDDAARALAQMANQDAQEQGERQEQAPEGEDEEGGNGEGDDRSEVDSEASTHIDSERLSQGEPEEDGQAGIRRRFSGFESLPLNLQQAIENEDQERFMRIAERMPADARERVFAAFPELVLTEEPRVLQVRNLDGHEPSSSSAAENEGENASGEGDSDDEPSGSQPSQRPEMPERGKSSIATEIKRILEEERRNQDLQSTEQTSMDEPDAERGSDGSWQHVSCHGGAPSRNGSRPSSPKGKGKSKASPEQLSSETGDPDRREESSSHLDGVAEASTDAQTTDALGASDDPLDSLSEDGNDNEDGSDSGLNNNPFHPDYEEQNPEPINPAPSPTTTPLGDAPLHPAVNPLDHNQGLWERINNWIWAGIPADDPGVGVDDEGANDERVVQDPANEEPFVPFLDGRPRNEDDVLQAENDEQDPEVARAAAQAGIDVNDPEAVEDAEDLEGMLELIGVQGPIVGLFQNVLFSAILISATVAGAVWIPYVAGKIVLLFLGSPFALCVKMPLQIASGLADLAVDLLLFFGGVCIYWAVTICRGFLVPLDYVRDTTWLQGPLRSAGDNVRGLVDSAFVGITRTFSAASTSWDSDHLYFSMSSHASLRSIQHGISTFFSPSIYVESLSQLGSIFDVQYAFGELVPGIPRAIMGAVGLTAHCVKGWFFEIFYGDALKWTFKLPGSKKALDPSLAYWSATDRMIAVLSGYSCFAIMGALYLTRREPMFTSQPLRKVESVIKDILHQAGGVFKVILIISIEMIVFPLYCGLLLDVALLPIFSTATVQTRMAYMMEHPWIFSFLHWFAGTCYMFHFALFVSMCRKIMRSGVLYFIRDPDDPTFHPVRDVLERNVATQLRKIAFSALVYGALVIVCLGGVVWGLYYGFDNVLPINFTSHTPAPEFPLDLLFYNFLTPLIVKVVKPSEGLHSMYRWWFRKCARALRLTDFLFGLKSFDERGHFVRKTWSAWLAAKDFSSTPTPVFGPDDKEAAEEDDSEVYFIRDGRHVRAPASDQVRIPKGAPVFVEVNESNIRIDGKPDEGVHASPDMVKMVYIPPWFRVRIGLFILTIWAFAAATGLGVTIVPLLFGRRVYMHFDTEVNDVYAFCVGIYTLGGLLYLGFQCQHLYRRAPAFFSAPLTTMLSRTVRQLATAAFRTAKVVYVYTFAVVVLPVLFTLLLECYVLIPLHMYMHAPLTTAATGQGFGYTIHALQDWTLGLLYVRIAHRVFLADARSRPARAARAVVANGYTDPDACVATRVFFLPCAVVFGVALGAPLLLGAAAQRVVGVVSAPPGGSGGAAAVTGDGHGMRVLAYRMAYPALLAAALSAWVAWGAVKAVRRWQSRVKDEVYLIGERLHNFGERRRLRMVNSGTKVKRLTIGIMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQU9</accession>
    <name>A0A6A6NQU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_113265</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Forms homooligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQU9"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000213">
        <property type="entry name" value="High osmolarity signaling protein SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="276"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="172"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="184"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="335" mass="35298" checksum="218650FFFA96D8DA" modified="2020-06-17" version="1">MPSYGSLGSPSLRKEAGISYNNRPSMFNVGYVLGNPFALATIGVSMVAWMIAFISSIIADARDSFPNFAWWAIVYMFMCIGGITLSVATDTEDMFSVSIVGFLAAGLVFTTSAVNSLVYSSDAAKESAAAGFILLSMVAIIWILYYGATANAAHRRAIDSFALHKSDRSAHADANAAATRNSRPMSHTFGSSHQDNSMTAANNAPQMVPSNQLNAGGFETSSPVSGYPGGPIGAGDANRNSSQPRFGGAGTMSSQANGGPIGGENSGEGDGGAPTEYAYRAKAMYSYEADPNDANEISFQKHEILEVSDVSGRWWQARKENGETGIAPSNYLILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR49</accession>
    <name>A0A6A6NR49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ZIP zinc transporter-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_107967</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR49"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000007">
        <property type="term" value="F:low-affinity zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071578">
        <property type="term" value="P:zinc ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF69">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="509" mass="54376" checksum="8A4AA91C988C7375" modified="2020-06-17" version="1">MDSLLLEAHSLLARQEEGEEEGPAPSCDDGNEYDGRMGLRISAIFVILVGSTLGAMFPVFAKRHKSVGVPEWAFFIAKYFGSGVIIATAFIHVSRHFPIWSRLLSALLPQTSFGSLSTSRLRGVPSLTCPSTDLSTHTNGNQLLAPAHEALTNPCLTGPIAEYPWVEGICLMTVFVLFFVEFIAMRYGEKTHSHHSHHHHGGDEESQNVAAAGPTAAAAAATTRDPAHLTDTSRGVANADDDDDESKGATPLQEMPHRGSHIPGTDHLGHSREHRDSEAIAGSEWAKGEHHGRYHDHSHDHDKEGGSKDVLSSAGAATADHHPPTNQGAMPGTIAESYAAQMTAIFILEFGVIFHSIFIGLTLAVAGDEFTTLYVVLVFHQTFEGLGLGSRLAEVPWTSTSTASSSSWRGTATPYLLALGYGVSTPVAIAAGLGVRETYANEARTTLLVNGVLDSVSAGILIYTGLVELMAHEFMFSERMRGERGWVVGAAMACMCLGAGLMALLGNWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR93</accession>
    <name>A0A6A6NR93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Quinon protein alcohol dehydrogenase-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_374282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR93"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="121"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="523" mass="52550" checksum="31C0BBB4A7430A4E" modified="2020-06-17" version="1">MSAHDPHSGQDVEDDDNGMLDAAEAEEEVQDEGDAAMDSGSDVEEIQLENDSAAYFDGHKDSIFCIAQHPVHPEIVVTGGGDDVAHIFDSTPPPRPVLPASYESNPQPAGERAGLASIFKIDGHTDSVNAVAFTLPKGEFVASAGLDGRLRAYRADPSGRLYRFVGEAQEVDEINWLASCPHPDYPNTLALGAGDGSVWVYTLSVDDPASPLTIVQAFYLHTGPCTAGAWTPDGTLLATVAEDGTFYVWDVFGAAAAGGIADAQVGGGGQAVVGLTPADERFRVDGGLYSVAVSPGGALAAVGGAEGKIRIVGLPRLGGAAGVGSTAASGAKGAGARSKAGGGKQAGGPKTGGGGRGASAAPSAGQAGEILASLQAQSDGVESLSFSAPPMTYLAAGSVDGSIALFDAAHGFAVRRHIRAAHEEEAVIKVEFVRPAPGAPVGPGGMAAGSWLLTSCGNDGVLRRWDARGGTAAAAKGLVGEWRGHRGGGEGGGVLGFVQGGGGGRVVTAGDDHVSLVFETPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRJ6</accession>
    <name>A0A6A6NRJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_115168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRJ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="234" mass="25965" checksum="D7157038F7F28AF8" modified="2020-06-17" version="1">MCGTFPFAESYGVDYYKVTYPAMSRKVYPFGLPAISSLYAGHSARLPIPMLSNSLPIMQRWDAGPVGKGFLAIPQAFYDSVLLGYGLRCRSTNRFSGAQILFNAFRWPPRSPSTDRTILKTSTHHESAGPACPACPTTEAGRKERVNIVSALVTAYIVVAVLAVLLVITLSSNRKQRQKTAGYWSIHELLMLNASLRRRCHSVNGRFPGIQTGFTQGNRIAHVAIWKRPQNYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ9</accession>
    <name>A0A6A6NRQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase II-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_116373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ9"/>
    <dbReference type="OrthoDB" id="10069473at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099122">
        <property type="term" value="F:RNA polymerase II C-terminal domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17003">
        <property type="entry name" value="CID_Rtt103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000030">
        <property type="entry name" value="DUF618 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047883">
        <property type="entry name" value="Rtt103-like_CID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF0">
        <property type="entry name" value="CID DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="20446" checksum="01B5DA747EB7F2D9" modified="2020-06-17" version="1">MAYTDDSVKAKLSALNDTQEGIVSVAQWIMFHRRHADRTAQLWQQRLKDSNASKRLNLVYLANEVVQQSKARQKKEFVMAFSNIIADATAAAYRGAPNDIQQKLRRVIEVWRARQIFDPAIQDAIERNVDGEFHLAPLAITRTSNCADAGPNQASPQNRDRPHPFQQEIRPRRWLTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSI1</accession>
    <name>A0A6A6NSI1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting 55 superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_352798</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OB-RGRP/VPS55 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSI1"/>
    <dbReference type="OrthoDB" id="14246at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034424">
        <property type="term" value="C:Vps55/Vps68 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007262">
        <property type="entry name" value="Vps55/LEPROT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050">
        <property type="entry name" value="LEPTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050:SF0">
        <property type="entry name" value="RH04491P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04133">
        <property type="entry name" value="Vps55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="13920" checksum="AEE196BB8C07D820" modified="2020-06-17" version="1">MAGLKTIIVLSFILAIGFLLVILSSALWKNYLPLLVVATYVVAPIPNWICGRAANPDDFMESSGSVLIDFGRFLTGFFVVMGIALPSLFAHCALIQYPAMIMSIVGGLLIYGTIISFTMFFQEENEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSM6</accession>
    <name>A0A6A6NSM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_94636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSM6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="262" mass="28850" checksum="E336F3B6B47BE88E" modified="2020-06-17" version="1">MARHWALRTASRPPQLSRVARPRRGIVIVVSRIGQRKKFQPFPSRLVAREWRREGEEEKFFPCFSGQDGFVARTSPADPQGRDTTTAQWPTRESAAGSPIRSQNHLPTSLVVILSSTRPASRIQSRPSPAPSRPLGKRPPPHPHALALFPRSIPPALSRAAPQRSARPPASRPPPPPPSPRAPRARTCREQGAQCRRHQSRLPSLLPYALRLSSCPSPGLQPGRQPSQFVVASAAPIARRVRCRERAAGSGLVSSGWTCPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSZ6</accession>
    <name>A0A6A6NSZ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peptidase family M1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_351766</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSZ6"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000004">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="13">
        <location>
            <begin position="155"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="11">
        <location>
            <begin position="380"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="12">
        <location>
            <begin position="671"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1014" mass="112693" checksum="A72FB1BAB0F036B4" modified="2020-06-17" version="1">MRYMKPPGSAVACRSRGVTCAPRSRHLPLSTVLSPAAAPAAPRPNCRWLRQTAASPRVAAALRPGRSSIARASCYSTTGTRCISSASPTYTSSPQQLTPTSRAHRNLAKPLYSPRAFVRHCSYQRTMCRHLEGAADATGSVDVTKGREVLPKNVKPLHYDLTLEPNFDTFEYEGKVAIDLDVVEDSTSITLNTLELKIHSTEISSGSKLVTSSPDLEYNDDSQSTKISFREVIPAGSKAKLVQRFAGTLNDNMAGFYRSSFDGPNGTKKYLATTQMEPTDARRAFPCFDEPALKAVFTITLIAPKEMTCLSNMDVASEADVESKMNGCTKKAVTFNKTPLMSTYLLAFIVGELKMIETDAFRVPVRVFATPDRDIEHGRFAVDLAAKTLDFYEKKFNSPFPLPKMDMVAIPDFSAGAMENWGLVTYRVVDLLFDEKVSGASTKQRVAEVVQHELAHQWFGNLVTMDFWDGLWLNEGFATWMSWYSCNTFYPEWKVWQSYVTDTLQSALSLDSLRSSHPIEVPVKRADEINQIFDAISYSKGSCVLRMISKYLGEETFMEGIRRYLKKHAYGNTETTDLWAALSDASGKDVEGVMAIWTKNVGYPVVFVAEDQASSSIRLEQHRFLRTADVKPEEDKTVYPVFLGLRTASGINEELTFTKREESFKLSSLNFFKLNADHSGLYRTSYTPERLRLLGEAAASKKGLLSVEDRAGMIADAGALASSGYQHTSGVLSLLESFKAEPEFVVWAEITGRISALRGAWIFEDEATKAALKRFQRTLVGDKARELGWTFGEADGHIEQQFKSLMFGSAGLAGDEQVVKAAFDIFGKFRDGDRSAIHPNIRASVYAIVLSEGGEAEYDVILNEYRTAKTSDERNTAIRALGRAKKPELIQRTLALPLSDEVKGQDIYLPLGGLRTHPEGIRALWAWMKDNWDLLEKKLPPGLTMLGSVVSICTSSFTERSQMEDVKGFFGERKTKGFNQSLAQSLDAILAKAKWVERDGGDVKAWLEEKGYHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI6</accession>
    <name>A0A6A6NTI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_352643</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI6"/>
    <dbReference type="OrthoDB" id="1937912at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000004">
        <property type="entry name" value="Histone acetyltransferase KAT2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="65"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="304"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2454754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="404" mass="46410" checksum="56F7C1AA4F49A396" modified="2020-06-17" version="1">MKDEAKRKADDTLETGSPTKRLKSASETPGADGEEKKEVRRVPFPEKPAVLEERNGEIEFRVVNNDGRRESTMILTGLKCIFQKQLPKMPKDYIARLVYDRTHLSMAIVKKPLEVVGGITYRPFKGRQFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATSDVMHFLTYADNYAIGYFKKQGFTKEITLAKPRWMGYIKDYEGGTIMQCSMVPKIRYLESGRMLLKQKECVHAKIRAISRSYDVHPPPKEWAANPNTPPCKIDPLSIPAIKASGWSPDMDELARAPRHGPNYNALLHLLNDLQNHSSAWPFQQPVNKDEVADYYDVIKEPMDLATMEEKHEKDLYPAPEDFIKDATLIFNNCRRYNTETTLYAKCANRLEKFMWSKIREVPEWSHVVPEKFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTL5</accession>
    <name>A0A6A6NTL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">S1/P1 nuclease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_307790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTL5"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="397" mass="43646" checksum="CB46C0354A29947F" modified="2020-06-17" version="1">MSAIVALETISAGHPAAPLTCSLTYYLRRNPVPTRNSGSSVNLQLLLLLLLPLQSVKEIEKQWSMHYAVPLSLCVFLSQASTVAGWGFLGHRTVAFLAEKYLTPAAAELVADATAYHPFWDISDGAIWADWEGRRKYEESGPWHYIDALDNPPERCGITWPRDCGSEDKPGCVVSAITNLTLSLTDPDFPSPLPKNETVLFLIHFLGDIAQPLHTENMSRGGNGIHVDFDGRRNSLHSVWDTDIPRKARGLHHDVRKPEEKAAAKAWAEELYALAQREEGRDEEERVRCRADAACEDVVPDCVDVGSPQACALLWAGETNCYVCDYVLSRSVVWLENNDLGGEYFEGAAPIVAGRIKRAGVRLGAWLNELAALDDGSSENGRVDEEGQQEPLGAAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTR9</accession>
    <name>A0A6A6NTR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PAP2 superfamily-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_351442</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTR9"/>
    <dbReference type="OrthoDB" id="2566866at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF10">
        <property type="entry name" value="INOSITOLPHOSPHOTRANSFERASE AUR1_IPT1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="7">
        <location>
            <begin position="204"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="431" mass="49342" checksum="B4AFE077E64109A3" modified="2020-06-17" version="1">MATAPNITVSVEEPEWNSKPAWKLPGWAEPIIVASILFGAMWMTRRRGYRILDRRRGRRSPYKSYLDGTAGGDSGRSSDELLSRSSSGWDSDDEDDWMRNSSLASASTNKHPPKVRDCCGLVRVQTPNSSRFRHHVHSRILQRFPFLIEMFYWIINYAFYRMTSITSQRLFAESGIWNVAQAHGIAVLETEQLSALSLLFPVRERDIQQWFMHGHQDALTVLNKAYALIHIPGTVGFIAWYYYVAPSHATFAVVRRTMTLTNFCAFLTFILYPCMPPRLLPPEYGFLDTVRHDDAQSVWMSGKYVNSLAAMPSMHFGYALCIGCTLVYHSAVFPRRPLEPREPRKSPFWKLWYLALGLAYPAFLLVTIVATANHYFMDAAVAACFVVLSFAANRVFVVFLPLEDWFLWAIRAEKPVPSTGKRFRERGGRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTV0</accession>
    <name>A0A6A6NTV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTV0"/>
    <dbReference type="OrthoDB" id="5283326at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF4">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="78" mass="8170" checksum="217A527E6E8E6C21" modified="2020-06-17" version="1" fragment="single">SCSTIQVYYSTGYSPLAAVTQPIPNDNGGGGQFQIGILKKPTETESVVNDGYQESGIFEGQVYGGIFVEDSADGCISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTW2</accession>
    <name>A0A6A6NTW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase DED1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase ded1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_96094</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTW2"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17967">
        <property type="entry name" value="DEADc_DDX3_DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000160">
        <property type="entry name" value="ATP-dependent RNA helicase DDX3X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044763">
        <property type="entry name" value="Ded1/Dbp1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 15 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="19">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="230"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="434"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="600"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="600"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2454872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="688" mass="72499" checksum="C2C778609F2A924A" modified="2020-06-17" version="1">MADQLDMNRLTLNESKHAPGSNGFPTERAPYIPPHLRNRPPPPPQPSAAPAPMDAGPPPVMNGGGGGGWAPPGGNQGRGYGRMNGPPGGGWGAGGGGGYGGGRGTPPDGANNSFQPRRQFNPNAYGNPGAGGSGPTARGSGDGQWVDGKHVPGPPNPRVERELFGVPNDPSKQHTGINFEKYDDIPVEASGQGVPDPVTAFTNPPLDPHLLTNIELAGYKVPTPVQKYSIPIVMAGRDLMACAQTGSGKTGGFLFPILSQAYLHGPSAAPAPPQPGFGFGRQRKAYPTTLILAPTRELVSQIYDEARKFAYRSWVRPCVVYGGADIGSQLRQIERGCDLLVATPGRLVDLMERGRISLCKIRYLILDEADRMLDMGFEPQIRRIVEGEDMPPTDSRQTLMFSATFPREIQILARAFLKDYIFLSVGRVGSTSENITQKVEYVEDMDKRSVLLDILHTHGTGLTLIFVETKRMADSLSDFLLNQGFPATSIHGDRTQREREKALEMFRTARCPILVATAVAARGLDIPNVTHVINYDLPTDIDDYVHRIGRTGRAGNTGISTAFFNRGNRGVVRDLIELLKEANQEVPGFLESIAREGAGYGGRGGGRSGGRGRGAAATRDVRRYGGGGGAGGGAPGGGGYGWGGPPQGGYGGGYGGAHGGGGGFSGGYGGGGYGGGYGNPSGGQSSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU84</accession>
    <name>A0A6A6NU84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Manganese/iron superoxide dismutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_95179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU84"/>
    <dbReference type="OrthoDB" id="275227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="100"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="279" mass="31088" checksum="B634FB779BD75282" modified="2020-06-17" version="1">MMPKLADEQSYAENGIPNFLTPDAFRISWSEYQAEMLKEVNRMVSNEGTLENDSLQTVILKSARDPAKAALFNHASMAWNNHMFFKGLTKEPVPIPRPTSDAIASSFGSLDSLRSTFIETAAAMFGPGFVWLVRRRGRSPTDRHDLSIVSTYLAGSPLPEAHYRRQPVDMNTQPQGSGAPPVDDTERARLTQVQNTAGAVGPYAAGGNAGTVAKRPALGGVELIPLACVNTWEHVWLPDWGIAGKRWYLERWWELIDWNEVDRLANFDSTKYMYVDSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUE6</accession>
    <name>A0A6A6NUE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_350752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUE6"/>
    <dbReference type="OrthoDB" id="4150821at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="35374" checksum="46F86707498ABE18" modified="2020-06-17" version="1">MPIRTNRIVRDANQRFRPNDPRTAVFALNERPPAYKPPVPTERVVLRGRVESPTLERDLSYFHEIVTGKLEPEKDKSPTLVLNLYRATLTHQRPIAERLTLGQTAGAPYYALYATPNTTSMDEFNTLVITRRSPNAGGNSDAWRQIHSAVYSDACTSIIQPRLNLHASGSMLIANLSRAGLPYTLSWSDRSTAGKLGDCFCVWDSRDGSGVAQMYSEEGWQSLDDSPLKGIIRIKRSRNLNSDMLNGAPDFEDPRFAPELAYLDFSRHSPQFVCQNSYAHENMDIIAAALLTVLVVMTRKMDQIREMGSLPAYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUP9</accession>
    <name>A0A6A6NUP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_349512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUP9"/>
    <dbReference type="OrthoDB" id="4586300at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="58602" checksum="0CB7EFDA7B592C80" modified="2020-06-17" version="1">MAPRDDDKKPDRPINPFLAFRDLVDEHVSSMLQSVIGLPSAITRQPSHSQWMDQNYPRDNAKSASGAAEQRKPDGGDNGSKETADAPTMPIEEWNRHAEGIREIMRQFWGRSDNEERDLFDKKVRERREQMKKFFEERRAGRSGAAVESSGDTCPYGPASPAQAERAHQRVEKMGEIWDDAAVPGNQREGVEEDSKNDRDGHGKEYVYCFDNFPARFGFQIEDPHTAFHSLWTDPFLDISSRFPISSRVYLSRSLYSPLWLEQHPVYGAQGARWRAAFEDLVKEEGGEVARPSTQNGEVESPHDWLMRVGKKPVGSDGDILGSYLTGIFNDLRDKYFDPTLPSIFDRASQEDRSQVPHAHHNEDTDPDTSADEYPDTELDMYERLLDLQTSASADSTVASTSKTTSSSYSYSSETTSAEGKPSILSELTTTTRELQPDGSMKTTTVLRKRFADGREENSETVHTTPAQNRKQIEAAALPPVEDRSVQTQAVEPQRPTDGSEGNKSQQKKNNGNRGGGWFWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUQ7</accession>
    <name>A0A6A6NUQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_397381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUQ7"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000246">
        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF0">
        <property type="entry name" value="DELTA(24)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="592" mass="65104" checksum="D1E55BDB2CD8F1B7" modified="2020-06-17" version="1">MSPSSPYDLDAHNTAVSGISASVSRFARSKTPFKVYHGSTNSTRITSFARDRIVDTSALNHVLSITRTSTTSTSAGTSSPTAKPKYPYTAFLEPNVPFDALVRATLAHDPPLVPPVVPEFPGITAGGAFAGVAGESSSFVHGFFDQTVERVEVVLPDEEGRVLRDVRPDGEGGEEGRKLFWGVAGSFGSVAVVTGLEVGLVRAGRREMGRGLKYEGRGDVGQKEREVQFLDGMLFARDRGAIVSARMVDAESPDAKGLKTVRFDRARDEWFYIYIDKLSKRAASSSRPSLPAANGSEQQQPIATFLTPLPSYLFRFDRGAFWTASYAFPLFHTPFTRLTRCLLDPLMRTRRLYRAWNASGFAQSYFVQDVAVPFESVAELVDWVESELPGGSIGGKWWREEKGRGVGHGQSKKGGVWPIWLCPLRVEGTGGVPLGARVGAKGRREVNETFAAADRSAGGKPQNVWGEDRSAAEKPSHLLNLGIWGPGPPSHDTFIETNRSLEQLLHTRLGGFKWLYANAYYTEEEFWDVYNKEAYEEVRKKTEAHGWVPSVFEKTRAKEERVERGRLRGVLAAVGGEGKGYLLKAKMAGKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV26</accession>
    <name>A0A6A6NV26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase phi-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_423100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYBBP1A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV26"/>
    <dbReference type="OrthoDB" id="342531at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000182">
        <property type="term" value="F:rDNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007015">
        <property type="entry name" value="DNA_pol_V/MYBBP1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213:SF2">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04931">
        <property type="entry name" value="DNA_pol_phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="740"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="830"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="748"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="773"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="830"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1051" mass="118107" checksum="BE243D54EC0880F6" modified="2020-06-17" version="1">MFRKRDRTTVRTDSQTANNHETDAAPPPSKRPKPNPDHFSTLSGFFSGLAAEDPDKRLTAAKDLMSFLVPGRDTVADPDTVEYVLYRLVRGLCSPAKAARYGYFVALTEVLGTLLGPRGRGARHTDGRVVAQTASVRKAVEMVAKYSVPEGKADKTDRSNHLIGRVFGYKAVLQSGILFAGKAPGEEWKEVLDAICELARQTPWLRVECGMVLYETVAELAKKPAGRVPFAESMIKILNERGLSKTAEGVAVWIAAKKAFPDAHFPKHVWHKRDPLCSNEWQQLATVMRGDFSKFGGEDSKELRVKGGSSEPFLPFSYVAVVNSMLERCLCEPKEGSKATSTFSKFWVDIVDNNLFSTSASLEKKSWGFQLLSKMLPLAPEEVIDSLFSPNLMRVLINHLTGKERYLHQSAKAPLSAMTKRAKDDGAVAAIIVKRLLEMGAFNFDHLTKTKTVEGIVEAADDSARSQLVLLFRSYLMRPPSLDGVSAETVRRVATDLLVTVVRTSNKLPLMDDNGNTSDNWMRIIIETFVKLGYFRPSKGLSRKDMDNVSIPPLSDEERSMIHSRFTSCIRSLLATDMKERLPYLTLGIRLMSAWNSSDSTDMQLVLEADQRVHDTLMQARRAVDSLERLCEQPEGTKKAFIPELTLLYVLNIFEAYSGDTDAVTVLDDIKQIDEWEVENEESRSLLIELLLGFLSKQSALFRKMAEIVFSRLGPIWTEENLRALSDLLEKKENLEGQQELFDRQDEVDMDVDVEESDVEEIDGEKSSVPSDSTDETQDEAQDDAGEESAPQDDNRRLESIDSEADPLLEKKIAELLKVAPKVSRKAEDGLLDHGHDFERSTQKTEAGVGSGDTEDSDDADMDDEQMMALDPLLTRVFQERKKKQTKRKEKKDAQETMINFKNRVLDLLTIYLKEQHSNGLSRTLILPLLRLIRTTSSQQIRNKASNMLQQYYTLCKKKGGPGHGDPRSLSLLEWIHEEALNTGPKTHGNACTKASLFFARNYMSSCDSNIEVIVDLYASTQKKWLKNSKGSLQPAFFVEWVNWLAEFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVD2</accession>
    <name>A0A6A6NVD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal hydrophobin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_365225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cerato-ulmin hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVD2"/>
    <dbReference type="OrthoDB" id="4500971at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23508">
        <property type="entry name" value="hydrophobin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.120.10">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010636">
        <property type="entry name" value="Class_II_hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036686">
        <property type="entry name" value="Class_II_Hydrophobin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341:SF1">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06766">
        <property type="entry name" value="Hydrophobin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101751">
        <property type="entry name" value="Hydrophobin II, HfbII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025604434" evidence="3">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="10614" checksum="84058CB4D92337E4" modified="2020-06-17" version="1">MHALTIVSALFVAAVSASPAPILDRRQTNVTDICTGLYGNAQCCATDVLDLADLDCFNPPSRPANVEEFESMCSEEGQQAQCCVLPILEQGVLCQDPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ5</accession>
    <name>A0A6A6NVJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_372935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ5"/>
    <dbReference type="OrthoDB" id="5405107at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025347778" evidence="2">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="16465" checksum="E039868A879E3833" modified="2020-06-17" version="1">MHTGLALLCLDLTQAGWSARTGLDCCIAIGALRDYEAQSERAAQHSAIAARQLRKTRTAQASAAAAVSASILSSLYLGSAALSTPAAALRAHVLLAALNLAASLAARAHVLSFWGPKGKVPLVGAFSDAVERSKAVARRLAVAAAVWGVAGALAALVWVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW57</accession>
    <name>A0A6A6NW57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_64389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW57"/>
    <dbReference type="OrthoDB" id="336321at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051988">
        <property type="entry name" value="HRR_RAD51_Paralog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46457">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46457:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="3">
        <location>
            <begin position="19"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="392" mass="42692" checksum="8105B36E74C35BF7" modified="2020-06-17" version="1">MLACNLFRGFGNGQRDPTSKIRVGTGCAVIDDALCGGFSHALGGISCISGGSGTGKTTIALNVLASHLLAQSSWHVAVIDTTGTFDVVRLLDVLIHRLRAQVCSESTSVASDEELAKRAEGLLERVRIMRVFDFTGLMEAIRELKEKLGEPNRMVVEHGRGIGSGRTESGCNKVTRAMIPDSEDEDDEMLLDPSPEKNLDGLEETLSMESDEVTKEAENLLKMIVIDNVTHVAGPTLKKNYVQGQAFLTSFLRELTYLSRENRLGVILLNTTVTPRDVPSEKSEGTMPDQTNAARENLPNCINQHSIFTSTTSYPALGKTFPYYLDVHVLLSSLPRTTANAVNIYGSGNGRISATKPAQLVNVLEVLADRWEARIGHWCSFTIEKGVELLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWA5</accession>
    <name>A0A6A6NWA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_347703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWA5"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="33582" checksum="4FD626679791FF10" modified="2020-06-17" version="1">MASGPLTRVRDFFLGPLTAQTNDSEPEPSEPSSPTSEFVIIQWLPSTQYSQDVTVRAISSYYNFLSTILFDLQPEEIDWPPPSGWPQITEEDGAYLNKNKTVIELLRHLPYFRQPQGDPFVWMQDTPVLCYQQGVGYADDHERTLFVDPYESEVPPHVVSLAHGLVDAYYVMLDTERGVIYWDGCREMPGTELTSTEVVEKRHKWKTYSTFLVEDFFEMLKQKFRDLKWIAVNPTDIREIDYGSQIDEEYNHMRKALQDAGWPGDGEGGGWDRDAAAKKFSEIEEEFDGPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWE0</accession>
    <name>A0A6A6NWE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_365106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWE0"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="221" mass="25791" checksum="A0E7220E50FC0065" modified="2020-06-17" version="1">MIDSSRGAEVAVDLYADDVLERPREFLRTLARYRCFDAKDPRDKVHALRGVLDIDDGNTMTVAARQLDGIRPDYGIEVEEFLDLLSVPRGGHYLNSTNYISRRQSMFDAYWQSLLAKTRLDDFDTEREQFMIWNIEFMRHRFLHILGLCHYPRIICIGEKDESTEKGDRIALFKGGKTPLVIRLCQTTDRWLLVGDCYVHGAMDGAFWLESYTNCEDFWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWZ2</accession>
    <name>A0A6A6NWZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cut9 interacting protein Scn1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_288291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWZ2"/>
    <dbReference type="OrthoDB" id="413993at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="399" mass="44726" checksum="F9CA58E2F7BC644F" modified="2020-06-17" version="1">MSNRQPKEEFPWDLGVFDAHCHPTDTLSSIPGIRGMRAKCLTIMATRAEDQPLVAKAADELGIAADLATSSWPESLGQVRPGVVPSFGWHPWFSHQVFVDDGRGDGRSALQEDAKVDHYRSVLTAQGNETLDRDFCLKLPDPRPLSEFIAETRDYLKRYPHALVGEVGLDKSFRLPEAWLPHEHASRDETLTPGGREGRKLSPHKVQVEHQKRVLKAQLQLAGEMQRAVSVHGVQAHGIVFETLQETWRGHERRVQSRRERKRRGSAPNAHSGEEPATNASKAKEALPKPYPPRVCLHSYSGPPEAVKQYTNPAVPAEIYFSFSAVINFSSSGASKTEQAIKVVPDNMILVESDLHTAGLQMDEKLEEMARKICDLRGWNLRDGIIQLRENWKRFVFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXZ4</accession>
    <name>A0A6A6NXZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_347610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXZ4"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="98" mass="11081" checksum="1E9F8EAE00D4A5C9" modified="2020-06-17" version="1">MAGLSETASVIAVVNMSAKLASLCFQYLVEVKHSKGNIEHLYRKVNDIKNVLEELQRLLDKQDKLQLFTARTLLDPLQRCSQELEGLEAKLKVKLEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY79</accession>
    <name>A0A6A6NY79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiamine pyrophosphokinase</fullName>
            <ecNumber evidence="7">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_372178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>thiamine + ATP = thiamine diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11576"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18385"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thiamine pyrophosphokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="7"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY79"/>
    <dbReference type="OrthoDB" id="25149at2759"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016966">
        <property type="entry name" value="Thiamin_pyrophosphokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031057">
        <property type="entry name" value="Thiamin_pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="Thiamin pyrophosphokinase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamin pyrophosphokinase thiamin-binding" evidence="8">
        <location>
            <begin position="175"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR031057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="29599" checksum="2995F4536828F410" modified="2020-06-17" version="1">MEHRPCDFLRQASYAAGLARPGLVILNQPIGDLGVFERLWRNSSYVLCADGGANRLHDVFGQGHADRREQFLPNNIHGDLDSLRDDVRQYYASRNVEVTRNPDQMSTDLGKALDKIRSAAPGPSRENTILLGTLGGRVDQALGILHELLRERRNHPAARLWLFSETNISFLLFKGENVIHTRFSEGFCTENVGLIPIFCPARITTSGLEWDVADWETSMGYRISTSNHIVDDTVTVHTDEVVLFTMERSPSLPEQEKIPIATST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY94</accession>
    <name>A0A6A6NY94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_386490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY94"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF49">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="338"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="562" mass="63508" checksum="57B1E41C4FBF7EE2" modified="2020-06-17" version="1">MLPQRNPVTSMTPLPTGLPLPLPRIQHDFAQNSETWRERYTREKRQATVKHSFEHAWNGYKKHAWMQDEVMPVSGSFRNVFGGWGATMVDSLDTLAIMGLDRDFELVLDALDDIDFSSVGADVVNVFETTIRYLGGLLSAYDLTDRRHSKLLEKAKEIGDMLYVAFDTPNRMPVPRWRWKNGALSGPQESPSQVLLAELGSLSLEFTRLSQLTRNPKYYDAIQRISDELEASQNKTRIPGLWPMTVNGKKMMFTADRTFTFGGMADSLYEYLAKEFMLLGGLHDQYRRMYEFAIDTAKKYLFFRPLNEQNAELLLAGTARGTVAGRVKLDPQAQHLACFTGGMVGIGARLFDRPEDLSVARQLTDGCIWAYESMPAGVMPEIFWAVPCGIDTTGDEGEMVEAAPESCEWSVDKWMRGVREFHNRRAGPNDVGMTETGAVRYSKKHRLAPGFTDISDGRYNLRPEAIESVFIMYRITGDRTLQDKAWEMFSAIDEATRTNVGNAGLKDVTSKSNVLLDNCESFWTAETLKYFYLIFAEPDVVSLDDFVFNTEAHPLKRPSVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYC1</accession>
    <name>A0A6A6NYC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pinin/SDK/memA/ protein conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_51974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYC1"/>
    <dbReference type="OrthoDB" id="330772at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="9">
        <location>
            <begin position="211"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="339"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="467" mass="51729" checksum="6EDFF862B00AB96E" modified="2020-06-17" version="1">MVDHTTTAVEASAAVKDPEGGGQPQASTSPLREEVATRDNSAGASPDGASAAPATAPYKRRKSSVSDTESRNGNNTREQVSRSKRPRLSPSVEGRHREPNRDHDTAAPPSTQDEGHDSESTRGHGHEHEHEHGYEIAKPHARASPSSRRSQSPPRRSPSPTTGLKRVSPLPSVNRQDSTESMDAQSTAGAGGRAGNAASRTERRRKSGQLEERRRGQRLFGALLGTLSQSGATPTQKRRADIERKQQAKLRLQAEELDAEKARRKEELVKERRGEQVRVGEMGMRVKHAEVLATAHFLHTRTEPKLYYKPWLLREEEKDIINDQIADAEDLVAREREEFAERRRQQVKEEKEREEEDKAKANGPRAQEMERKVEPMSEEPAIHEDAGHGESAKDNSTANGNEKGTENMATLDPKDKAVHEDGTMQRLEEAELSQPFPAQEVEKDAATGHQDDAGDVVLEAEEDTVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYP1</accession>
    <name>A0A6A6NYP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SAM and PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_286899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYP1"/>
    <dbReference type="OrthoDB" id="422827at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="173"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="651"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="807" mass="88843" checksum="77748954504870E7" modified="2020-06-17" version="1">MTPITPLEPGVEMFQSRKYQPLIQPRTTAPRPLSEATEIFDTDLDGDDSSEFEEDSPKYSFESNDGRRSQTTISTYDEVSTPRSGRRSHFELHIHTEPSKPVEGPKGPHLFRTSHASSDFSFDYALQMSPLLPKESPLRAPTAFRRPMDDYVANPYDDPTVDMPLDTAELPFWSAQQVALWMANAGFDQGIVEKFEIHDITGTVLIELQFDHLKELGIASFGKRHRLWTEIQALRGTDGQFSPVQTPFQDVDSPVHDTKPQKRHRDKQRTRHRAGSPEDVNTPNTPAGNHRRRGRKHRQGGENQGTPLSIVAIEQLVPKPHKCHKGEKCPKWRKQQRQLARLQEENRGFPISPENGGHIVISGDPGNPHSADKVVDNVYRPTSENVPSLVASSDILGPGQLPDFALQEEMLRSLESRDPQENVKQFLSLQKIEPPAALTHSATATPIVERPPTPPLDMFPPLQPPSNGSGPHSNLKSLPRLSIPESQSSSRGIYSGRGDGCSSALGLDPDSAVSPCRTAITAVASPGGSLYRFGTPCSEMDVPVTSVPLGPVSRDTSQSVPPNMLFRDPIARSASRATARPSFVLPSLNEGEVYAPPPQSDGNSTFNTETTAVAETESISFDKERASTAGITSVTDQAGHQRRTKGFKYENVNHAGWMKKRRTRLLRHEWQDHHFRLTGTQLAMHENELPSSGAIDTIDVDDYTVACSSLASNKLAAKLKSLKIAGGAAKKDGSNEPMAFTFQLVPAGGKDGNSSELRKLAVIGGKSYHFATKTRDDRIEWMRELMLAKALKAKGEGYEVNVNGESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ35</accession>
    <name>A0A6A6NZ35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_345981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ35"/>
    <dbReference type="OrthoDB" id="5065855at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.395.10:FF:000008">
        <property type="entry name" value="Ulp1 protease family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="24"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="240" mass="27838" checksum="C540DC4A6802E0EE" modified="2020-06-17" version="1">MSSFHPFKGKVSKHFGDRLSPEDAYLSYYDTRLTREDIDSIKDDWLTDNAIQFWCEYLEQEKLKKEFPEANIILLRPVMTYLLMFENDIRALKTALPDLSKTTHVFLPVNDKHSVDQAGGTHWSLLLVSIIDGVAFHYDSLASCNKIDAMSATRKLEQLIRKPLRFMEMEDSPQQDNGSDCGVFVCILMKHLLLKRLLLTDARGKISMTMGDRQLNAWQGRKEMLKTIESFRKEGERRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZK4</accession>
    <name>A0A6A6NZK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytidine deaminase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_305242</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Also catalyzes the cyclization of FAICAR to IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZK4"/>
    <dbReference type="OrthoDB" id="6017153at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.20:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.440:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="13">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="612" mass="64991" checksum="0F13C16765778DBB" modified="2020-06-17" version="1">MAAPQKIAVLSVYDKTGLLDLAKGLTAHNVRLLASGGTARLLRDASFPVSDVSAITNAPEMLGGRVKTLHPAVHGGILARSIEADEKDLAAHGIAKIDFVVCNLYPFKETVAKVNVTVDEAVEDVDIGGVTLLRAAAKNHARVTVLSDPGDYAGFLKELSAGSDSDAAGAISKPTRERYALKAFEHTADYDAAIATFFRQRFASDAARGPVQHLALRYGTNPHQKSAAAFTAAPGAALPFAVLNGAPGYVNLLDALNAWPLVKELRAALGLPAAASFKHVSPAGAAVGVPLSPAERAVYMVDDVAGLADSGLAQAYARARGADRMSSFGDVVALSDPVDAATARLLAREVSDGVVAPAFAPDALAILARKKAGRYLVLRVDPAFEPPPLELRDVFGVRLSQTRNDARIAPDESFGTVVVPRAGDGAVLPASARRDLAVATIALKYTQSNSVCYALNGQVIGLGAGQQSRIHCTRLAGDKADSWWLRFHDRCLGLRWKKGVKRADKSNAIDMLCSGQVPAEPGIEREDFEANFEVVPETFSDAERKEWGAKLGEVACSSDAFFPFVDNVYRAHRSGVKYLAAPTGSQNDQAVFTTAEKLGITFVEQHIRLFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZU4</accession>
    <name>A0A6A6NZU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_42054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZU4"/>
    <dbReference type="OrthoDB" id="3504677at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8021" evidence="1">
        <location>
            <begin position="201"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="34042" checksum="40E7B72B32A7A298" modified="2020-06-17" version="1">MKEYTSLAKHQRHIYHGRPWWWRRWSPVPASAFGLDPSDSTTTDHSELVMLRLFGGYVLGWLALVAPAAAQCSREMLVDTTDAYVAAQETGDVSAMTLADDVAYLENYGDVAIDSGLLAQGLAIDHSRSTHDTTLCATYTELIITDPSHPYVIGTQMQVAEDGSVTQISSIVTDDGDWLFDAEGTLQYASQETWDPIPEDQRDTRETIQAAGDAYLDLFNDKSVEVPWGTPCARLEGGMYTGQGNPDDSCNVGVPDGLDLTNRRYVIDETLGTVDVFLNFGGPSGMPDSHEFRVENGKLRYVHTMTVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZU5</accession>
    <name>A0A6A6NZU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CTLH/CRA C-terminal to lish motif domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_345412</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZU5"/>
    <dbReference type="OrthoDB" id="1933455at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="391"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="6">
        <location>
            <begin position="391"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="468" mass="53289" checksum="30C81AD24AC17CDC" modified="2020-06-17" version="1">MAEHTSTKLNADQQVSLDQFLLRVPVSIISRNLKNARRLVEREKEWIAKKLQEEIAKGDAGDAQQSAEVVGELVKRLKQLRTKMESLDSELHKLTRSLHARVDHLNQLYTIPSLADVKYEQWSGIRLDRMMVDYMLRQGYIEAARQLAKEKEIEELVDIDAFVACLRVEKALREEHKLGPALAWCSENKQALRKVEVRLSLPLGKRNHPMADFEPASNLEHELRLQEFIEKVRTQNLETIVSAREFAQKYLAPHKDPNFAIRAAGLLAFSPNTNQEPYKTLYSTDRWHYLADLFLAVHHQLHNIPERPLLHNVLSAGFCALKSPSCHSEKISPRQADAEQVLSEEGAGPDSVSDYEFTEDNQPVKPAHKHQYKLHHKGPGGAAALALNSICPICSTELNELARMLPYAHHSKSIVEPDAVVLPNGRVYGEARLRLANEKMGTAEGYVKDPMDQERVFREEEMKKVFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZW6</accession>
    <name>A0A6A6NZW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_392022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZW6"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034315">
        <property type="term" value="P:regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057334">
        <property type="entry name" value="PH_2nd_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112:SF66">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25353">
        <property type="entry name" value="PH_2nd_LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="135"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1190" mass="131898" checksum="26254E78E629D3E2" modified="2020-06-17" version="1">MPKRRSLFTRPQLSALTTIHDSREREKEPRASSSPILASGVLKKKRSPSFHLINGSTPPKEPDVGIEEYVPSPDGVGAAPQPASRGSSGRPTSVFGSFRSLRSNDFMEEPLTSTSSNAPSVNWGDALDNYGRSRNVIYHGEVQTSSSLFRKKKEYLVLTETHILRFKNCHRAAESFPIISPPPVARRLTNPRHSSSPSIGSQQELQTVNSEHSGEERPRDFGTPLRQIVAVYKIDDGRPFFAIEFACLDEEANNGSTMMIQFNAPDERDSWLTHIRAAADAVRLADTNPISPRNSNRCARVVEREGDYEPPNYAIYKVVQRPAKSTGRNSSDDLTKIATTVCFMAIGVHKVHLIPLARGHSSSSVALSSLNVQGAYGIMTMTNMRVREEDDGFELTFRMPLQPPKVLYLASLASRDIAIRLRHVETFLRPEWESRPYMFMVPEDVRREILAERSPERVPEDYFDRTLTAYCIAYNLRPRNIRYGVLDSDEDSPHFVLYPPEDPKQKYSTLELLAVMRALRYNECFGTVSFAGVVLDSLNMLGDAYGEEHLCTRTKRGSPVSLDHQVLRDAHLLIQEVRAMAMTNRRLRRMDFTGCIKRVPKVSDNPKYRDPGCGIVEALFPLCRAQATNVDWISLNHIQLADSDLDYLVGAASERLCHFRGLEMSCCGLTDRTMSLTLDALRAQENTLEALDISDNQVRLSPLIFEPEIRVFGFIRRLDLSKTARTSAAEPLISFNTLKLWRLQMLRLSQTVLNTQDVASLAQYLQTKHSSALRELHLDQTTLTGGDIATLMYCMAHDVDGEARERDLYLDISQNRPTTAHRDLAEAIAQGWAPTRVSLRYLEYSDEAQFRELVRALGKNNSIRWLDISRCSLPSDASEDTCRELEKMFARNSTLLGLDISGENSRLEQAKIGVGINHALCGLMRNNTLQTLQIRNQNLGVQGASTLADVLKVNTALRVLECDDNNISLPGFTDLVNALYHNTTLTYMSPMLEAREAHFRMTEQQIRQASEDASKQHPASPPPAPRRGPPVHLTEQDIGAALRLVEESWDRQAYRLAQYLARNAAVAAGVTDAAALAVDDEVFERPGSAGPPTGGAGSASRSGSGLGMNGIAGGGGGCGGAVGVPPDVRGLMEKVVVERTPTVEKDGRLGVADGVDGSVSRTSLGHVRTESEEERMAWAAEVDKRLDGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P051</accession>
    <name>A0A6A6P051_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P051"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="819" mass="90950" checksum="CCA98E6A2414FA89" modified="2020-06-17" version="1">MTVGRRAVASIICPSAPFLVPLRARSTYSAVRFSPPIIHARNASVATQQKKKPAQSPRTQSKFLRQLKHRRKLEKKQQPRAPESSNDIDCATRFRDALKTRRSGETTTAIKLYPEMVDKTLLTSGDMKALCQALHQHCRIGLRRGRNIDPEIDFGETIIKDMRERTAPPDPWASLHLLSLLKEAKRYDRALAFWDWLQHQSDDYVNASVYGAAIEMLAYHGHKTLEDLEELYETALSKFPGQFLSYHLSPEAILPDRSQHFHGADLHMLLLQGITVARVLMGDWRNAYVGLDVALRLSPDKVPRYLFETFIHERPLAEAYAVFMLACRAGIAPPTPTASRFLASLTNKILGISMSRKIDFATKVELAQGVFRAVKAYVGAGGRLDGPLLSALLKPMVLLLYHSPTAADAAGSEPPGEGEIQEVEKRSFAFNRRVAESARQFLIDLAHAGAKIDNEGPLNSVATIGGRAGCAPVVRWSIESFDGLNITPSDVLYRNTLLAAGHLGEQRLVRTSWELLVEAAEDPETDWRIESRDWEALVRACKRVGMIDYVDEQVAALPHTLTKEGERKIEQAKKAKLLPIVFETAKDAEEAKVLEQVATTGLESLREEVKGMKTVLGRPNGMHDFAEEPVWMHLRQGGTPTAVASARETLRDVYEELSTDPATHAAGQAEAIGDPMDTEDPEAAADVATSTETADKLSEGDAEIGIKSSSEPQRCFIKPEKPMSSTGFTLDALRFENWFTITELLAMAEAREAKRQTAIDKAIKSGKPVADEQDTFIIGPAVAGCDGQVDRQYREMTRDEWKQEALRLRGIRQGRCKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P057</accession>
    <name>A0A6A6P057_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycogen synthase kinase-like protein-3 beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_36861</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P057"/>
    <dbReference type="OrthoDB" id="272141at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000055">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000009">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="34"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="395" mass="45414" checksum="8EE2EC26C85B7711" modified="2020-06-17" version="1">MSQGRSTFNSLRMGEVVREKVQDGLTGDYKELAYTQCKIVGNGSFGVVFQTKLHPSGEDAAIKRVLQDKRFKNRELQIMRIVRHPNIVELKAFFYNNGERKDEVYLNLVLEYVPETVYRASRYFNKLKTVMPILEVKLYIYQLFRSLAYIHSQGICHRDIKPQNLLLDPATGVLKLCDFGSAKILVENEPNVSYICSRYYRAPELIFGATNYTTKIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTPTREQIRTMNPNYMEHKFPQIKPHPFNKVFRKADQNAIDLISRLLEYTPTQRLSAIDAMVHPFFDELRDPNTKLPDSRHTNGGSRDLPNLFDFSHHELSISPHLNRQLVPPHMRPVLAARGLDIESPDFKPLTKEQMMARLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0G5</accession>
    <name>A0A6A6P0G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_37657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0G5"/>
    <dbReference type="OrthoDB" id="3483554at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="11212" checksum="DEC11840FAEFE816" modified="2020-06-17" version="1">MRLDTTELRRNTLITHADHKTREDTPYISFTNSPSSLQELADFRTSRGGDQSIVIVDPHTRIELGLPVLRYREEMEEYKIRPPYTRDYWSNHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0H9</accession>
    <name>A0A6A6P0H9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Inosine triphosphate pyrophosphatase</fullName>
            <shortName evidence="13">ITPase</shortName>
            <shortName evidence="13">Inosine triphosphatase</shortName>
            <ecNumber evidence="13">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="13">NTPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">XTP/dITP diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_345542</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ITP + H2O = IMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29400"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6)-hydroxy-dATP + H2O = N(6)-hydroxy-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:83971"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:233529"/>
            <dbReference type="ChEBI" id="CHEBI:233530"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:83972"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XTP + H2O = XMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:28343"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13 14">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="13"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0H9"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009204">
        <property type="term" value="P:deoxyribonucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.950.10:FF:000003">
        <property type="entry name" value="Inosine triphosphate pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03148">
        <property type="entry name" value="HAM1_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027502">
        <property type="entry name" value="ITPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00042">
        <property type="entry name" value="RdgB/HAM1 family non-canonical purine NTP pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="66"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00093218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00093255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00093271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2457318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="20916" checksum="F0C8F8D44EFD88A6" modified="2020-06-17" version="1">MAPKKLNFITGNKNKLAEVKAILGDTVELTNQSLDLLEIQGTVEEVTLDKCKRAADIIGGPVLVEDTCLCFKAMNDLPGPYIKWFMLALGPQNMHKMLSGFEDKSAQAVCTFAYSEGPGHEPIIFQGRTDGKLVPSRGPTVFGWDSCFEYEGQTYAEMDKAEKNKVSHRGKALDKLKAWLQQETTQMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0X8</accession>
    <name>A0A6A6P0X8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hepatocellular carcinoma-associated antigen 59-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_25390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0X8"/>
    <dbReference type="OrthoDB" id="5627at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="170"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24023" checksum="4D2FF4BDE647BC99" modified="2020-06-17" version="1">MRPTSTYSKMADLRAPREGVATAAAASTAADALSSSQQAGHDADDAARPLRPDDVGLQRQPAGLGKLHEVDLGPDSTLRNIARTAQATRKLQSGEAAEPEPKLGPDGKPWRNRKRRTSEDIRRDKLVEEVLKETRLDIYDEPEAPLDTNDDQAADDRIAEKFRRDFLDALSTRANRRHAAPKKKKDNNAEQRPKGPKMGGSRSARAAMRAKELEAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1I7</accession>
    <name>A0A6A6P1I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_285370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1I7"/>
    <dbReference type="OrthoDB" id="333551at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025066">
        <property type="entry name" value="CCDC174-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13300">
        <property type="entry name" value="DUF4078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="368" mass="41574" checksum="5B7D9E79619B1E7F" modified="2020-06-17" version="1">MTSKDSSLYGIPRPKKATTKEISSSSTLAFTSNLSNLIASSRSRNADGSTAKTAPGRARPPKKGDIFTQHNKGSKKRALKDLEEENPSQASRQKHTTHGSTMDADDFKRSRRKMEEKARLYAAMKRGDVDDEGGRHMVDFDRKWAEKHASRDDASNASTASDSDDGDDDDDEEEDVVEYTDEFGRTRRGTRAQAAREERRKRMQTAAAEDDRFSARPAAPTSVIYGDTVQSEAWNPDARMAAAMADLAAKRDRATTPPPDEHFDGSKEVRTKGVSYFRFSQDEETRKEEMEALERERRETEKAREERDRKREERRKLVEEKRKAIGEKRGKAKADKFLNELMGEFDGNAGAQESRSEEQEDLLKGAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1P6</accession>
    <name>A0A6A6P1P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_371468</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1P6"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF166">
        <property type="entry name" value="LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="257"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="259"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="429"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="586"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="664"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="447"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="590"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="671"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="688"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="748" mass="77290" checksum="A6EEB6B38222A12C" modified="2020-06-17" version="1">MTLVHNGVPDLQPLDMAPQMRPLLRAHKSFPYAMRPPSQGAGGAAAAMMAGAGGILGGPHPHHHHNHHHHPHHQQASTPLNGSSAASPVGAVPPRERITISNLEDVDAHAAAAAAAVAGGVHPFGGSAPASPISRLTPPSPPPPPPPPHQHQQHQQHQHQQAGDGAEAEADDGLDELDFGPDPGAGVEGMEVGLPEGALDVGGEEGQDDGDGAGSGQDGSGGGAGSGKDGQHGGQGQGQGAQEGEEHKPTAAELRAQKRKMKRFRLTHNQTRFLMSEFARQAHPDAAHRERLAREIPGLSPRQVQVWFQNRRAKLKRLTSDDRERMMRSRALPDDFDMTQALHSPFGAPPAQAMGGTPLSSPGGYQPAFPEGSMVRPLNLDALRRLPEASHHHLSPTGISPAFGGFNFTPPQSATDTLVSPVSATAETNPFSFGAGPMDQRSPGRAVSGGGGGGGGGGGGNPFGGSVTSPGFTSHPQHHHIPRLNIHDRMQRGSRGGGEAVSSPLRTSMSYGGADGGMDGGAGADPAAMAAAQHMGQDPQTGGPQGLPYGIGYNYGQIPGFQAAASQNRMRSFSAGVPRRIELSTAHYTPSPRSPVAGGPGAGAVHHQQQQHQQQQHHQAPQTATFPSYGSHHAQGSPLGPPHHGFAQMLSAPHHITSFQNSYLRQDAGTPGSGGSGAGGPPGSAGSQAESQFGAQQGAETGFGEPGDDGAAGGVHAEHHHHHHHHRHQHQHEDGAERGDGLHLGPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2T5</accession>
    <name>A0A6A6P2T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2T5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="11882" checksum="3DEF0079554F51DF" modified="2020-06-17" version="1">MAFDSVHLPRLSFFFSTGPLLGWLALFIFVGGFLSLGRSPGMLFARLFTQSIYLSIYPLLSFPYVSKNPFAFPLFWFRFLASLRARSALTVFKCSLASLRYTFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3E8</accession>
    <name>A0A6A6P3E8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative FAD binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_342019</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3E8"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025441596" evidence="3">
        <location>
            <begin position="22"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="565" mass="62174" checksum="D657C43DF180FC6A" modified="2020-06-17" version="1">MVPKVAVIFFIGLILCHRPNAHHHGPWSPPYERRRCAFGNNCWPDHATWTAFNDSISGRLVRSFPSAARCHEAQYDEQLCQIVRDNWDNSFWRTNQTGAYSAILWELGNDRCFINSSVSAPCGQGLVPYYSVAAQEVSDIQAAVRFANYKDLYLVVKNTGHSHLGRSSGKNALSIWTHNLKGKQWHDSFVPVGAPRDTQGQGAVTLQAGEQWLDVYEAAAEQGVIVVGGNARTVGTSGGYVTGGGHSAWANKYGLATDNLLEVTIVTATGDHEILNTFTDPGYFYAVRGGGGSAWGVIISVTYKTHPNPSHLQLGLVQFNATGSSAVRTVQSAVMKSLVDITSAGYTGYGVFDQGFSGIFIQPNGTNETFVEAFAPFYQLSTYPNVSAVIGNFTLPSWIDYCDAFLTDPNIGTNIQDASRLLTADILLNKTDDLIDMISDFPDAPSGFNFIGKVNPTNRANTAVNSVWDFSHALLSFGIDWADDEPAHVKTERKQRLVEISRRFDAVIGPDGGTYINEANPYEPEWQRVFWGDKYETLLKIKHRVDPTNLFVCNRCVGTDIIFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3N0</accession>
    <name>A0A6A6P3N0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_342290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3N0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="11840" checksum="5A9E34F52447E6A8" modified="2020-06-17" version="1">MGLRRSHVCVYICMCVCMRDVHGARTPLHAKKRSNAVVVPRRLPFRFNPSNPPAALSLSCPAAYTGHGSTLSRKSSRQVASCKALLACSSSARIRVRQSGAHITVQHVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Q0</accession>
    <name>A0A6A6P3Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_362875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Q0"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22762">
        <property type="entry name" value="OTU_fungi_OTU2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049771">
        <property type="entry name" value="OTU2-like_OTU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF10">
        <property type="entry name" value="DEUBIQUITINASE OTUD6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="154"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="34202" checksum="FE65B72F955A553C" modified="2020-06-17" version="1">MDELLARHRKEQRDLQSRITQKKKAATKKTRKGVNDECATLERELKERQKREVATLKGDNDENDESDLIVEDEPLQDSVDAITKPVEQLSLSSVLEQQESNKQRKPNRAKARLARRAAEQEAMVAAAAEEAASMPDYRELERKEMLAEFEKRGLREKVIRADGHCLYSAVADQIDQLGLSLKPNIKPTIISEGEELPGYKVVRQVAADFISNNSGDFVPFLEEPLEEHVRKVRDTGEWGGQPELLALARTYHVRINVLQGDSRVETIVPDTTDNTKEIWLAYYRHNFGLGEHYNSLRRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4X5</accession>
    <name>A0A6A6P4X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-1,3-mannosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_339332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4X5"/>
    <dbReference type="OrthoDB" id="5410040at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40020">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40020:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025369673" description="Alpha-1,3-mannosyltransferase" evidence="2">
        <location>
            <begin position="36"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="19314" checksum="D9946D8B2694F0E3" modified="2020-06-17" version="1">MPPAGLHPRSRLTTSLFTTTLAVSFLVVAIPHALPCPVPPRAFADARADLDGMFDPDEQSQQGTRRRCRKRRSKSLGQDDMARAEKRGAEGGADGEHKPSEAAGPLWVRGERWRKMRTRECPVPKPGGLVGQVLGFKAKEESDGAGSECVPVVKVQPFRERRVGTREENRDSDMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P513</accession>
    <name>A0A6A6P513_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_283337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P513"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="77"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="627" mass="72647" checksum="681597B6665699BF" modified="2020-06-17" version="1">MESPASETSESDLEEEQHDTEVLSGTFSQLAITTESSPYNPLETPDAIRIIHLQPGTGADRIVCELSTVQLSNAPPYEAISYVWGNPNITEPVECDDSEIDVTVNLAAALRRVRLRDSPRLIWADALCINQKNIYECNHQVRNMFDIYKNAERVLVWLGTDPGDHADGAFALVRNIYQRIKQLHAAKGGPFVAGKQHALSEREVDELHTGLGDSWASLRIVFLNDYFKRMWIQQELGIARKATLMCGDNEVDWKMVYYTSRFLNMEGKQIRKRYRCDPENARRLYRWFDDRLWERNKFSLEQICDIMIQSKCSKPHDRVYALIRHPLFRSIGPFEVDYHKHQCDVYMDLVLKWITKRKSLDFIGQFRHSRRLFYKQTEEQHWPTWVPNFAGYDDVHGVVTRWVGTFKASRSFPPDVNVDQNARVLQLKGFAIDSVSKRSQRLKEKQFILSAPRKSYRIFLPDSPNPPEGHKTILKLKKFEAFLLTLVQANLEEELEQLREGMAYWQRAAMEDEDLAPQFHAYEEALKTTQTYSVHAPWEYFMSSAGLASRRSRVFCTRNGYLGLGSDIVRNGDIVAILYGGKTPFILRPKDDYYFLVGTCYIHGIMYGEAVDEFEWAGCLTEEFEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P530</accession>
    <name>A0A6A6P530_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_338981</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
            <location evidence="1 6">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P530"/>
    <dbReference type="OrthoDB" id="78652at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF27">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="23"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="8">
        <location>
            <begin position="192"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="450"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="613"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="665" mass="73388" checksum="2F77E6C8C523070E" modified="2020-06-17" version="1">MEWFWATVTYMLPVEPPEGGDKRGCSGAEIINRLRDEAQTGYPDIEEAAVDLSKTAEMAWLRQLSSWVLYGRLPSYGTEDFFIHEEEIEDGPPEFRSNSRLLPKFVSAQTASSILFIGRSLNHIRARKANLESRSSRSSELTLLPCHLEELGKVKAPITSASLSGTVSAIRASLSRNTLQELLPLPKIIQILTLLRDFFLLGRGEFAVALIESADECLRNRTERSASHKPSTGVRGLLFKDSELNGVLSKTWSTLSSLVDQDDGDNFSADEILDLARDIVRLSVSKQPAPTRPSTPGRAREKDDILPTLPMSLFNDVLLSVPTTLSLDISSPLDLFLSQPEIDIYSTICSYLLGIRHSHVRLASLWKETTLRRDHPAPLAGTHCATPTGKNLLRVRRARSKARNIEMRKVWATCSAAVFFLAEAGAYFEGEVILESWRHFHEWLVGPSNERPGSRAALRQQGDRSASGTPQPPDMSTLSMHSPGVVRQSFASSQHQPDSGVPLDPESLAAAHKRFLSSIVHALLLSDLPFTTSLRALVSHTDQLVAFFARLRAIQTNLDLEEDEGVVDALADYANEEKEVKLELDRARKRIDGDLKALVGRLREVDVERVSGGPGGIVGKGGGRGAAGRLDEKREYEPWKSGGVDRLLMKLDFGSVVEEEDEGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P540</accession>
    <name>A0A6A6P540_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_196094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P540"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="28643" checksum="8112EBE10B909910" modified="2020-06-17" version="1">MMPATVMRSHRPSPRLLGASWRIPPWRINAFGARDNGRSDRQVLFQPCRSSRARAGMQLRPPANATAEAHRLVNALLGPAIGPRLHPPTPIPVRPSTAHHAGRPFDLALTVSPSQRRPRAPGPPIQPLSTPRRANWAFLRPGLHRRRRPTHTHLPGTQARQHTDKSTHGQTERRSSPPPISVANLAARPPAHHAAARPPRQRAHLPLEPRRRLRRPPRARQLPAQQRQLLDERRGARGVLAVVIIFGVGARARARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P548</accession>
    <name>A0A6A6P548_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_339830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P548"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="18970" checksum="DD67A921C0E11581" modified="2020-06-17" version="1">MLELEPWQRRESSLKFMTRAVASMPNDAGYASASIEGRVAVEWFDPSPESQARKYAFKCHRQQGTAAEDGNAPVDVVYPVNALAFHPVHGTFASGGGDGMVALWDGVAKRRIRQYQRYPASVAALSFSADGKYLAVAVSPGFEDGKEGGVEDEEGGVVKIFVRELAEGEAKGKTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P568</accession>
    <name>A0A6A6P568_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_339369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P568"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="18115" checksum="58219DFBF255E2A3" modified="2020-06-17" version="1">MSGFPSLQPAFTVQVEIDAPLAVGSASRNTPLNVVPMTGITVKSEPGFSPALDATHMGVGYDYIHNDPSGEQMRLDVRSQLKTKEGALLAMYYKGPVDITPALMKILGGAPDAESTPFGNSFVTFSFETGAPEYKPLENMMFVAAGRFLVQQGKPVIVEYKVSRVLKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P576</accession>
    <name>A0A6A6P576_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_384997</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P576"/>
    <dbReference type="OrthoDB" id="496at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22881">
        <property type="entry name" value="Mdv1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000881">
        <property type="entry name" value="Mitochondrial division protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF28">
        <property type="entry name" value="CCR4-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="303"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="345"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="438"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="553"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="214"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="386"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="397"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="672" mass="73362" checksum="1C6D8F613F94AC9B" modified="2020-06-17" version="1">MTHTNPTGHPPQSRHLEAFSRKVSATATHLIDNTGVSQHYANALGDLHRELRRPGMQRGVFAFAQTTPRDLVRSTLSVPEIQHRALSYVSDELLRNVPEGRNTYSLFEGFRATVEGAEDAPGQKALVGSEVEPEPKGSKGARQMRNRKRGLNHRLEMMGIRKNMCAAEITEIDTKIANLNKMRRIVLERLADLEGEEADLEHELLEVANKLEDLQEEGEDEDEAAAAGQKTPTTRGANGDNDADDDPASPGFMSESIYQKLPSSPRSKRRQRPGGAAGAHRARRVSTPILHTHMEPGTRIKELAAHTDLVTALDFDYPFGTMVTAALDDTVRVWDLHAGRCMGLLEGHLSSVRCLQVEGNIVATGSMDASIRLWDLSRAEYAPRDAPYRRRGRDGNNEDEEEEEEEVDEDDGLTFGNDEDAPPPPPPTSMQDCPLFALEAHVAEVTALHFRGETLVSGSADKTLRQWDLVKGRCVQTLDVLWAAAQASATLNTNSSTSSSGGGQWRNAGGRLPDASADFVGALQCFDAALACGTADGMVRLWDLRSGQVHRSLVGHTGPVSALQFDDVHLVTGSLDRSVRIWDLRTGSIFDAYAYDNPITSLMFDARRIVAAAGEDVVKVYDKADGRHWNCGPGVAPDAVEAGSIANVERVRLKEGFLVEGRKDGVVGVWSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6A7</accession>
    <name>A0A6A6P6A7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_337956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6A7"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="78"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="33323" checksum="D6A50384EF8C5AB0" modified="2020-06-17" version="1">MTTPGPASEVPDQIDTQPLRLPYLPAPPSDGSDEALLQLPPPDMPRWSEDSTILLRTPGSCVEKLLSNIVVKSGRAVLLDEAHGLQFASQLDLPGPRLHKAQQIGDNVVAIHMDFVEGQQLDELWPNMSESEKLAIAHQLRDILQTMRSIPSDSGIIGSCKGGPARDCRRICAYKGGPFQHQEDFNKFVLDLYEVTPTTIRDALTRSLRSDYRILFAHGDLTQRNIIVKDDKIVALIDWEYSGWFPEYWDYIKFFERHSTNRDWKEYAKEIFPETYDNELVLFQAITRWQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6M9</accession>
    <name>A0A6A6P6M9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_282175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6M9"/>
    <dbReference type="OrthoDB" id="5577209at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14364">
        <property type="entry name" value="CUE_ASCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052586">
        <property type="entry name" value="ASCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041800">
        <property type="entry name" value="ASCC2_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494:SF0">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="329"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="692" mass="74792" checksum="CD8CF330A0A71145" modified="2020-06-17" version="1">MASKLPPLASFPPATLRKGIPPAEWDACLDAWISSSSAYLSSAQETFEKACEDDTSLSSFLISFFREFSRFSSGDSLLRSEKAAQLRRQAFLLTHRALTSSSIPSSLLGWSFLSDVCRCFLRSAHLQKLLSSVWRRNGDQLEAQLQAVKASFVKRLDSADPGESDDDLHQIAALIHSSPDAAFYIMSGSDFLDSLCVAYINANAGRQLRQTLVTITYFGLTGLTRGEKPKYSLLSDHIYVLKANAEQVQKKNPSSPSLLSDLVTNTPFIPKLRDSTSESEGARIGNLLNALESFRQPGIARPRRPAKRSTSKGKGKAIENGHDGDMHIHRMSKITHVQDLFPNLGSGFVAKLLDEYNDDVETVTANLLDDSLPAHLREADRSEELTPPTSSPTHLSPPSPPRSPSPYLPTRRTAFDNDAFDRLAIRPSQLHRGKHHATTTADALLRDRSRPSKAAILAALATFDPDDDERDDTYDAADVGGTVDKADAESGTDEAGRQRRTAGGGAPDGVDPAVEEALFRAYAADAALFGRGAQVRRGAPRARLRQATGWSDEAIEGWAVMLGRDARRLRRLEERFGDAGLAGGRRAQEEVPRTAWRAEEDEEEGEEEGAGEAAGGRGGRGGGGGRSGRGGGGRGRGRGRGAGGRGGSAAEPADEKGTQVARQRKEANKGSRANHNRRDQRARKMARGGFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T4</accession>
    <name>A0A6A6P6T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_419996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T4"/>
    <dbReference type="OrthoDB" id="2117972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="225"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="62665" checksum="EE34DABADCA67F11" modified="2020-06-17" version="1">MDQTEVELESFRRQWKEEVSARAKSNAAASPSSSHAESPKSTASGSASHAAKRSKAPTIPSSARSELQGSLEEFQPRSYHDIEPNETGHRLGDPGSSSCAARKEPVSALEHYEKAAERERLGSLGDSVSLYRKAFKLDSKVHEKYRNKHFPAAAYKPSASQIQQSTTSQQHEQQPNPSDAPVTVPNTAHHSLHGLSPSLLDLLSQFSKLKIAGEVPPTDASPRPSCPISKLPEELLVEVLVHVAIEDVAAFARLAQVCKRLAYLILTEDRVWRRVVQGPEFGFAAMHYRFACKVDGTPVSSLRPRRLGTGARTPSALDDDGDGDGDEPCTAAQAVLATPPPLTAAYPTYRHMFRARPRVRFNGCYISTVNYARPGGPSANQLDWNNAPVLIVTYYRYLRLFRDGTAVSLLSTAEPADVVHHLGWEGVRAQRGAAGGDALPGAVVKDALRGRWRLSGKGFGKTVGGGGLMDEAAGTEGPFWEEGGEDGPVSRPDDEELDAEEEGTLHVETEGVVPKYMYKMAFAMGSAGRGARNNRLAWKGYWSYNKLTDDWGEFGLKNDRPFYWSRVKSYGTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Z5</accession>
    <name>A0A6A6P6Z5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dopey, N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_282035</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DOP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="297643at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040314">
        <property type="entry name" value="DOP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056457">
        <property type="entry name" value="DOP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007249">
        <property type="entry name" value="DOP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056458">
        <property type="entry name" value="TPR_DOP1_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14042">
        <property type="entry name" value="DOPEY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14042:SF24">
        <property type="entry name" value="PROTEIN DOPEY-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24598">
        <property type="entry name" value="DOP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04118">
        <property type="entry name" value="Dopey_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24597">
        <property type="entry name" value="TPR_DOP1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DOP1 N-terminal" evidence="8">
        <location>
            <begin position="37"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="DOP1-like middle TPR" evidence="9">
        <location>
            <begin position="392"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="DOP1-like C-terminal" evidence="10">
        <location>
            <begin position="1379"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1060"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1881" mass="207640" checksum="47970C1E0E9BAE0D" modified="2020-06-17" version="1">MSLDPLAQRPAISPASSGRASPVARQLRRGPEYGVKDKTFRRYASGVERALLLFDTTEQEWADYISFLGRLLKALQARTTTNIGPVPHKALVSQRLAQCLNPSLPSGVHQKALEVYGFLFSMMGKDNLAKDLHLFFPGLAPTLSFASLSVRPAFLSLFEDFVLPLDFWVLRPALKSIILSLLPALEEESAEDFDRVFKILVKLKEAVRENREIGSSKIEQGDSTFWQCFFLAAITNQSRRPGALAFLMRSLPKLGPLARRQSSAGGSEDEPNLPPPAEGVISPEPGLLVRAFTAGLEDQNLLIQRGFLDLLVTHLPLDSPVLQKRIRAEDLQRLVGAAAGVVARRDMSLNRRLWTWFLGPDPPADEENGQLKSPASGQNARAGDLGSYHAAYFARFGCHPLTRSILAMINKPSSSAPQRARPLRICLSLMDRWEVGGLLVPEIFIPALESVYQYGEISTKSQLDEVLRSTSNFFDGVESGLIWGKVVELMTTSLRPGAENPSDRLKRLKLVRFIITNFNLREEEMLLCHIPLAALTILSMLSGCATSKRRAANIDNAAIELAFSIADSLIQLLHERAFRQTKESAETPAGLDKVVQQTVLTRISDFYVKHDGNLEASPQPFEPQVLSLLLLRECTGLFSDALCSNAPRGILEHATKTLCSLVHKLPGSILAGKVELLPIFLEVLGADEEPGNDQRDVSFPVISAVATTLAAFQETGAANPVVPPSEMPPLIHSMVSCLWRYLSPVMPKYHVETVRVLWQLQALTPAERHVEASITALMSTSVLLEKNGPEVSAEAGRRFAVIWSHTMHEQEAYAEKSGRNSRRRSAANTALTMLAGSINIYQLMLTRPLVRTLDALAEEETELFAFVKTWLRDLPSLNRVFWVVAVHLSPLLQHQSESETEKSSSTKDSTTTSIKRRQWQRASKDYLYWMQTLSRILKWASDYTWATIASNVFGVRNGAETDNPELPLPIFFARVCVQAFELSLLGSFSGNPIEISLQRSALAIIRQILLSPCAETLGALHLDDRFISILIKSVDKFNPALQSSLLQVILAAFHARAQNQPAASTPEGRLSSRDGLSASTGRSSITKDSDGVDSPLSSQKPPSQLVDCLRVGFSSPSNRVVLDDWVNFLSEVFPVFPETMFQNLLPLIECFCAQIKLAFGQLQATFQEATIPKHEAPESTLISLMNGLEQTLARAHERLLQDEAKSAASKSPEQPQGFFGNMVSGVFSSDVQQTRSATANSRLSVLLCFQDTVRMCFEIWSWGGYGRDHLPPDPTSFASFNHTALRMRNRARRILEHLFAAETLECLETLVSRWRDLGDRKGEHAAIFGLLNVLNGSRPKNTIPTIFNAIYGRTHPGSLDALRVSTLTSDLTDSNLALFLVEYTRSLEDDAMDEIWADCIAFLRDVLANPMPHRQVLPVLIEFTATLAEKVDNTNFGDQRKLRKELGDIFLRLLAASFTSRSLSFLQEPSVHHNSGNSKLSEKASRDGNFDILPSLATVAPTIPLVLGDNDRVANAVAGISTSILGPAMRAKVFPENVSSPLLDLLSKLSHIPQASKIWKRDISEAFSDARFFSTPLDLVKDYWIAILHEWILNDRDRIPELLSRLSPPTTAGIMFGVGATSARTDADRRTQLNLRRTALLVVAAPDEAVIPNLSGITEKLAELLTATTSTSPSSATRAEVFLLLRALVIKLEPVHLAALWPIIDNELRLALLSLLPDDDAGEVYNSSAVVHASKMLDVLVALEPDEFQLHEWVFITDTIDAVYRPPNWQPTAIVDDLAEALSNATTSPLESHAFALPAQPASTAESSEPSRRPLLDRFMQDLDAADVKAMPKQELTLRVLRPYMGQLSISAFEATYSASKPDRKACMEGLVKDLFDIGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P703</accession>
    <name>A0A6A6P703_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Valine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_281027</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="4"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P703"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000009">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000020">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000078">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000005">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="16">
        <location>
            <begin position="149"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="17">
        <location>
            <begin position="816"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="47"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2459781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1103" mass="123966" checksum="F60427580D22E57E" modified="2020-06-17" version="1">MALNAASHNVAGEKTGPVSGQPPSLAEDSKSAILGASESDPTGQHAPGRDGGERNKEKKIKSEKELEKERIKAEKAKKFAEKQAKMAQGGGGGAAQPSKKEKKKAEQADAQSKMAPYVEQTPKGERKILQPLDDDYHKAYIPAVVESAWYDWWEKEGFFMPEFNEDGSVKDAGYFTIPIPPPNVTGALHCGHALATALQDTLIRWNRMRGLTTLWVPGCDHAGIATQSVVENMLWRRQHKTRYDLGRPKFTELVWDWKDEYHIKINKVLKRMGGSFDWTREAFTMDPNLSSAVTETFVRLHDEGYIYRSNRLVNWCTRLNTALSTLEVDNKELEGRTLLDVPGYDRKVEFGVITYFKYPIDGSEETITVATTRPETMLGDTAVAVHPEDKRYKHLIGKNVKHPFVDRLLPIFGDEYVDPEFGTGAVKITPAHDPNDFTLGQKHNLPFINILDDDGTMNTNTGSFAGQKRFDARYSVVDELTKLGLYVKKENNPMKVPLCSRSKDVIEPLIKPQWWMRMKELAAPAIDAVRSGEIKIRPETAERSYFRWMENINDWCLSRQLWWGHQAPAYFITFEGEPGNRADDNLWVTGRNEEEAQTKAEKKFPGKIFTLERDQDVLDTWFSSGLWPFSTLGWPNKTNDLDKLYPTSVLETGWDILFFWVARMIMLGIKLTGKVPFTEVYCHSLVRDSEGRKMSKSLGNVIDPVDIMDGITLKELNDKLLMGNLDPKELKTATKYQQSAFPQGIPECGADALRFSLVQYTTGGGDIAFDVKVMHAYRRFCNKIYQATKYVLGKLPASYTPPAAGALKTGRESLAERWILHKLTIAAKDINQALTDREFSRSTQVAYQYWYDNLCDVYIENSKAIIQDGTEEEKRSAVDTLYTALEGGLTMMHPFMPFLTEELWQRLPRRPGDATPSIVRAAYPQYAAEIDDPEAETAYELILGCSKGARSLMAEYAIKEDGKIFVQTYDDATYTTATTNVQSIKSLAGKGIASVSILPASSPTPTGCAVFAVSASAAVFLEVKGRVMIDTEIKKAQGKLRKAAEGAAKQRKILDAPDFQEKVSEAVLGTEKQKLDDLMAEQRNYEKSIEQFEQLKLEEGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P735</accession>
    <name>A0A6A6P735_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytosine deaminase</fullName>
            <ecNumber evidence="14">3.5.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Cytosine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_281735</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>cytosine + H2O + H(+) = uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16040"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from cytosine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.1" evidence="14"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P735"/>
    <dbReference type="OrthoDB" id="408702at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004131">
        <property type="term" value="F:cytosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046087">
        <property type="term" value="P:cytidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019858">
        <property type="term" value="P:cytosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000016">
        <property type="entry name" value="Cytosine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF190">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="17">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00060700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00066550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00074321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00084039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2459770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="142" mass="15020" checksum="572D7EDF706794E3" modified="2020-06-17" version="1">MESDPGFQAALEEARAGAAEGGIPIGAALVAADGRILGRGHNMRVQKSSATLHAEIAALENAGRLPASAYKGATMYTTLSPCDMCTGACILYNVARVVLGENNTYLGGEDHLRSKGVEVVNVKSSECQALMEKFIDEHPEQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7J9</accession>
    <name>A0A6A6P7J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras small GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_190007</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7J9"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00876">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001856">
        <property type="entry name" value="RAS small monomeric GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="25345" checksum="7728BBCB2A0169EF" modified="2020-06-17" version="1">MDDDNRISITVCGDGGCGKSSITLRLVRSQWTHEYDPTIEDSYSVTRTIDGQTYFLMLTDTAGQEEYRGLWAASNLRSDAFLLVYDITNAASLDALDYFMQMIEIETEQRLDNGGVPPVKIVAGNKCDLQGARQVRSQQGLEWARKRKCGFMETSAREMVNIEETFALLVRRVVEARRLQIYGGVEPASARTQPLAPVSEKPAMAGADDDDARNKRSFWSRLRCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7V1</accession>
    <name>A0A6A6P7V1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sds3-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_361827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7V1"/>
    <dbReference type="OrthoDB" id="20886at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="645"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="703"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="814" mass="87344" checksum="9455B924A6BBEC49" modified="2020-06-17" version="1">MSALPRSSRSRSKPASDLRDAAARRSAHSDRSASSTATVNDRTPTPPTSTLGATTDDAGPHSLNPDPADSHNPDTDTTAMAEDTAAVAAIIGHHVDRATRDDAVTYTDTDGHSSSLTELDEALDESADGSVGGTGSAAVANAADTPEDDEDVEDEDNDTEAETERLDATPRSNRSAAAATTATVKTPSKLANELVTMDEQRDGDDAANSPSARHWQENGGAATAAADLADDDRLNGPSPTSSLLHDKAATTDSDIPLAAANGSKKRKRFNVGESSGGEDTDADQPARKRSGSTKDRPAIDASSPPAEMDLEEDNAAVVEEEDAPADASGAAKDEDHELEGGDHVMEDAEEVEDEIVVPAKPAKSKKGKRKGKKATRDHDHVERANGTPAVEVEEAAEGDGEEEDPGAVDEEHAKKKTAMEALGGIEKQFQTFREKMVNERIAQLTRELNLLDQPGAPHTDFQTMVRALEERRDDKIQIETKLLHYKRRCLDTQTVAQRSQILAQYRQTARELRENAIDLCGQFWHELQVGRRKWGADEKDFVYKYNPDRPGLIRQQAAYNKEVSILSGIAKHVGFPAAPEIKGLEESELEEDLRAMEISCASSKPPTFGNFEHHTRETTAAARTTDPNAAEARYYEQTLWANSQYPAHQHQPPPPPPQQQQQLSGSKPLKHAHAPLSTTSKPSFSTPVFHRRRADADPPSGPPNGSGSTIDLAASNPPSSAGAAHGSSAPRGTHSAEHAHHHRHAHPRGNFVADVDTPVPRRAQSPNRVDARFIVEALASRDTRQHQQAGPGGAAATAPYQAFPTSGVHGAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P821</accession>
    <name>A0A6A6P821_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_299402</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P821"/>
    <dbReference type="OrthoDB" id="342900at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024687">
        <property type="entry name" value="MMS19_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12460">
        <property type="entry name" value="MMS19_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="7">
        <location>
            <begin position="40"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 C-terminal" evidence="6">
        <location>
            <begin position="561"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1052" mass="115755" checksum="A361BDDCDC676D83" modified="2020-06-17" version="1">MSDVELYLSDADRNKKEASATAARSAQRLESKEISLLELIESLREYVNSDDAQRRARTLSYLAEVLGALRPGVLSGQQRHLLFDFIISRIANDSEGVGASAKALVALEALGKWDPEKPAAIITTLLHYTHPLRQFKSQHERYSVLILIDLLMAKYRTAVHGIHTAVPDFLPQFISYFDGEKDPRNLMVAFSILKVPMTEWEIGSSAQELFDAVFNYFPITFRPPADDPYGITAQQLKDRLRECISSTPDFAPYAFPALLDKLDSTSMNVKRDVLTTLVDCIANYGVRTVNLYAVTLWDALKFEVLNVQEEDLAEGALSVMAEIGKQVTQAPGPLASYLKPITKECNEHFEDAPTKQSQAAGRILRAVAAVSPKSVNFVLDAAIPTILALYQSADSIAKRRGLLEGLVQLLHADTEVFGEWYTTTSRPLLVNGYNAPNRGEAGSNALVKYCERIYQILGSGLQTSPTNEVSFRLTALDGLLQLSKVRQLLADGTISSIIKLFTDIAVHEESAGNDEMKERAINALLEVAHQKPQLVVNTAFPIFMAALPDTDADGSEQYGPVLEAFAKLGGDGQVFKTVVLRLKNKLNSAVQQQASPQYLGAILSAILYAFANSAQELEDRGDFVPYYQDVLRPLLEQMTSTGSAHSTSFDDERILDLIGRLCNIILRHQKTEDQAEIAVEMYGFLHRPSPQQAAPYNQGVPDRDKRLMIVSVHLVAALQRDVPLPTDPRSLLTALVDFSMIDSLSPGVRAATLRKLTLVLNKFIPTSELKPVVEPILFSPRELLATSNLSLLSIRTLFSIIRALVLRNSSLLSTVFPALLDTLADHTYGPVVARGFSTLLQPDDFVTKENHCNISSLHKQKAFNMLVPALTTSFRDATPDTKPSYLVALSGLLRWLPYPVIESEVRSLAPLLLQSLDLTLPEDPNLAADVKAATIATLIDVLGQNPRAIEDHAGSLIARLLGVTTAAPAKRPNAPGTTRGGAGDPKVRGLGLRCLALVPERLRTETVVPYRREVVKKLTGALDDRKRTVRAEAVRCRAKWMNVDEPDADEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8I5</accession>
    <name>A0A6A6P8I5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_281209</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8I5"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025478081" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="251"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="443"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="478" mass="52784" checksum="93865DE83FF6E992" modified="2020-06-17" version="1">MRLQSSLAAAAATLLLGAGPATAAGGLYSSKSPVMQVDAKSYDDLIRWSNYSSIIEFYAPWCGHCQNLKPAYEKAAEELRGFVNVAAVNCDDPANQSLCQKFGVQGFPTLKFSIPNKKYGGKPFIDDYTLGRTTKHIVGAMIDRMPVHMIRVTDKSIDRWLEDGNSTAKALYFTDKDAPTALAKSVATEFWGALDFTFLRKKEKKFCDMFGVTEFPTLLLLPGGDAPPVKYEGPPTKDAMIEFFSRAATPNSVANKGKKSGPKLSDTAQEPVESHRGKPGAPAAAPTPSGQKQQVSLEQRLRIATLGSEALVRERCLQPSSLNCLLVMLPETDWSGEGYPPDADAALASLRKVREKHAEKDYALFPFWIVTPDNPVQELLRRELDLAPKSELAVVQTNGKKSQAREYASTDYSYAALDNWIDDIRMGGGKRYMIPNHVVKTMEEWNREQQQSGGADEQQQQQQQQQKPIQAEDGHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8K1</accession>
    <name>A0A6A6P8K1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_405739</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8K1"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000006">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF10">
        <property type="entry name" value="ELONGATION FACTOR EEF-1B GAMMA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="93"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="232" mass="26077" checksum="D7109D9E50045565" modified="2020-06-17" version="1">MAPFATIYSSVAFRHPRIVKGLAAANINGLEVEIPPDFEYGVTNKTPKYLAKFPQGKIPTLETPDGFCLSESTAIAYFLADSGPKREQLLGRDTRERALIQQWVSFSDLEIFETTLPLLLMQLGRSPYDEAAVTRKEGNARRALTYLNGHLKGRKWLVKDDEVTLADLSVGGALSIAFKYYLDKEARAEFPEIPRWYTELTKMKEVADAFGVVETDFIETRLSFQPAGKLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8N1</accession>
    <name>A0A6A6P8N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'/3'-nucleotidase sure</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_369326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8N1"/>
    <dbReference type="OrthoDB" id="4018688at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="5'-NUCLEOTIDASE SURE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457:SF0">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="29765" checksum="B2520B62F1351707" modified="2020-06-17" version="1">MNIIQSNDDGWAEINIRTLFDTFEDSGANVVLSAPAENKSGSGSLDFPPTEREEPCQFDSCPAASPPVTEPAARLNYVNSFPVTSIKHGIDDVAPNYMSNPGTAIAVTGPNVGSNLNVAVFVSGTVGAATFAAHERGIAAIAFSGASGDPTPFDAPETPLYSRIYADLAVNLTETMHAASAPYLPEDTYLNVNFPEVTESRCNDAAQFEFVLTRIFPRVSIVMPEDVETCGSTTLPTETSVVNNDDGCYVSVSVGNAGSKADASPEEQAQVLDVLQGLLSCVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8R2</accession>
    <name>A0A6A6P8R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Urease accessory protein ureG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_298109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8R2"/>
    <dbReference type="OrthoDB" id="10063137at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05540">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000208">
        <property type="entry name" value="Urease accessory protein UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715:SF0">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="7">
        <location>
            <begin position="52"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="252" mass="26657" checksum="75FDF9A89B27868F" modified="2020-06-17" version="1">MATHSHGGGVSHSHANGADHGHSHEILEGPGSFLGREMPIMEGRDFKQRAFTVGIGGPVGSGKTALMLALCRALRDRYSVAAVTNDIFTREDCEFLTAQAALPAERIRAIETGGCPHAAVREDVSANLAALEDLHRAHAAQLLLIESGGDNLAANYSRELADFIVYVIDVSGGDKIPRKGGPGITQSDLLVVNKTDLAEIVGADLGVMDRDARKMREGGPTIFAQVKNGKNVNHIVDLILSAWKASGASHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P987</accession>
    <name>A0A6A6P987_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BTN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_419321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the battenin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P987"/>
    <dbReference type="OrthoDB" id="5965864at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="292"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="61376" checksum="1C51DF8940BF8BA3" modified="2020-06-17" version="1">MLPMPGSPGATWALYRARLKAVFEGADPRVCAAFWFFGAFLARREPERAALQRKQRDAKPSFAIEAPASREKAPLRARAHPATLPTYPNRSPYAVRCRARSLINNVLYVIILSAALDLVGPDFPKGLVLLFDVVPSFATKLVAPYFIHHVPYSVRVLVFVALSTCGMLLIALTPSSQPPAADGDTATHTLLVAESGSAIASRMCGVALASLSSGGGELSFLGLTHYYGPFSLAAWGSGTGAAGLGGAGAYVLATTTIGLGVRTSLLAFSFLPVVMLVSFFVVLPRGPLRLERPAPAARPGGYERVEGDEDDDARSEDGSDLGGEVSARAESAEAQGERDTLLGTSLRSSSGRSFDDATAKAKRRGGDGGAGLLSGFRANLRRARHLFLPYMLPLLLVYVAEYTINQGVAPTLLFPLAASPFSSYRAFYPAYAAVYQAGVFVSRSSTPFVRVHALYAPALLQVANLALLAAHALFFFIPSVWPVFAVVFWEGLLGGLVYVSTFAEISEKVPLAEREFSLAATSVSDSAGICVAGFVAMAVEVAIFFEDVSILEMVDPYASKWQRPQYYSLLTGLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P994</accession>
    <name>A0A6A6P994_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_384116</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001345">
        <property type="entry name" value="Related to ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="843"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1072"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1104"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1139"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1182"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="463"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1250"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="769"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1612"/>
            <end position="1634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1653" mass="180244" checksum="73316994E9C57E38" modified="2020-06-17" version="1">MAARATMRRIASQTWTLTKKNLLIVFVRHWLSTLIRAFFGPVIFMFFMSYSKNFFIPPATYGFGSPTGLRSFQDALGSATGGRDTVAFVNNGFTGGQISGVIDTVADTVRAAGKRVEIVESDNDLLTTCRSSLRGVSTCFGAANFHSSPEEGPGDLWNYTLRSDGSFGENVFVDETDNDQEIYILPFQHAIDAAIASAEGTQLPDDVDEYIYTDQTQEERDDAIQRAYMNSIIDIVGVAFFIGMVGVVYQLTGHMALERELGISQLIEAMTPNQHRWHTQLARLLASHLAFDIVYLPGWIIMSLFVARLVYPSSSVAILIFFHILAGLSLSSWSILGAALFKRAQLSGITITIASLILAIISQVAGPSNSGAAAILALLFPPMNYTLFILYLAYWEHENRAGNLIEGAPGAPFQLPGIALWIFLIIQTLVFPVLGAFVERGLYGTASRARKINFEDTDSSTAVKLNSFSKMYGPSWWQRNVMRRLGATIKEEVRAVNDLSFSALRGEILVLLGANGSGKSTTLDCVAGLNTVSGGTIEVDGIGGLGYCPQKNVLWDELTVFEHVKIFNSLKSMGTKASKHDLKELISACDLELKIDAASKTLSGGQKRKLQLAVMFTGGSRVCCIDEVSSGLDPLSRRKIWDILIAQRGKRTLLFTTHFLDEADRLSDHITILSKGDLKAEGSAVELKHKFGGGYRVIIYNNLKTKLPEELDMYPKRMLYDHTEYQLADSPTAAVFVKKLEGAGIMEYQVNGPTIEDVFLKLAQEVNENVEEGQAQEGDEEISRKGDSPDGFAPQSSSSAEKKVARSDDEAEEEFQTGRGTTLARQTWILFRKRITILRHNKLPYLAALLVPIITAGLVTFFIRGFEGLSCSPESQASDPRTLSLQRLALFNELEMTVGPPDRVDVEQLARRLQVNTSAFNLVDSFDAFQSSIRNRYANVTPGGFFLGDTPTMAYVGNREIAYSALTQSVFDSVFSDTNIATQYQRFAVPFSPDTGDSLQMILYFGLAMSAYPAFFALYPTTERLRKVRALHYSNGIRAAPLWIAYLCFDFVFVMVISAVAIGIFIGVSDIWYYPGYLFLVFFLYGLASILMVYIVSLFVISQLAAFAFAAGGQASLFGLYMCIVTYVSPDAIDSSLTIAHFVFAVISPAANMMRSLLLTLNEFQILCRDRELASYPGAIKVYGGPILYLIVQAIVFGIFLIWWDSGSVPSFLDFTNRRRTPDPESKHSDIDPAVTAEAQRVIDDPTDPLRVLHVSKAFTKHTLAVDDITFGVPRGDVFALLGPNGAGKSTTISLIRGDLKPSPVPAGSYPAGPDVLVDDTSISRHRAAARAHLGVCPQFDACDTMTVAQHLAFYARARGVRDPKRAAATLARAVGLAAQQKRPAAALSGGNRRKLSLAIALAGNPSVLVLDEPSSGMDAASKRVMWRTLRSARVSAGRALLITTHSMEEADALAHRAGIMAGRMLALGSSEQLRDRHGDRVNVHVVRRDAPRTPPDEMARVRDWVERKVPGAVIEGGMWHGQLRFSVGGSRNSGSGSGDGDVNGDDATTATTAAAAAKAPRRGYGDARMGIAELFALLEASRDEIGSEYYSVSQSTLDQVFLSIVGRHNVEEEDSGAGGKGKAKGKGKGTRSGWRWGAEIKKGLGALTGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P996</accession>
    <name>A0A6A6P996_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_280209</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P996"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="13">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="103" mass="11415" checksum="C2D0E606AC643126" modified="2020-06-17" version="1" fragment="single">GDAKKGANLFKTRCAQCHTLKEGEGNKIGPNLHGLFGRKTGSVEGFSYTDANKSKGITWDENTLFEYLENPKKYIPGTKMAFGGLKKGKDRNDIITFLKNETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9L0</accession>
    <name>A0A6A6P9L0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_280735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9L0"/>
    <dbReference type="OrthoDB" id="4721035at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="726"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="842" mass="90646" checksum="59155FA958985993" modified="2020-06-17" version="1">MPKRVSINSIPRVPVGAKSASPATPASDAALLGTPSLTSPPPGHARQFSAGSLSSPQLPSPGYEGAGGVAGAGVSPGGGGLLDSRFGKSQREHPSVSSLGSFRQPYQHIPDNERLAGAGGIPNTPGSIKSAYDGGFRPTEECPAHKNFYQGRANWLSICVMVLSVYSSVFSGIYLVIALKGPRYGRMIGSHGVLTYSTASLLTALFAKTIELSFVTVFVTFLGQVLSRRAFMKSQGKGITLAELTMRSWIMQPGTMLTHFESVRYAALSLLGVVSLFAAVVAMLYTTAADALVQPQLKFGGWEKKLLAGTVGASFANPTYLADNCRTPIADSDDAAKGTTCLQIQYAAQSYHNYQRYLSSWDEVASNGDGTTDLNTRPQGFALLNENTTVLPSWIDVQDVADTSTENRVVHNVSMAMPHPGVIRAARDEINGIMQPEDLEGIGIYSIHASVPSAVISVTCANMNETELEPIVFEAWNGTLDPAQWPAAAPQAPEEGYLNETVVDDIFGWGAKYGTNPPVFAKYPLEYNTILNHTAYPWGRPSIYLLGNAPETPEYPNQYFMCQMNASLTAYCSTRYNASQSGGSLEAICNDPPDDMAYIKSLHNASSGADTLSGDWLNIAFEWGNSLALNYGITDGNASNARLLTELAIRIPSWGGSPQLSPALPSPAEALAVLSGSTLLMSTNNAPFVPFWNYSKAALETPQYQYFNASIRAQEYASGGVYGYQLGFHLVLFLVFLTNVAVLGYFVVHKGLITDFSEPPNLFSLAVQSPPAEVLAGSCGAGPEGEQYKVNWFVSKEGEHLYMESGDPGVKWRKGRQSREVELMQSPISRSYEEFSKRRSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9P4</accession>
    <name>A0A6A6P9P4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9P4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="19278" checksum="B2103FF250EB0F5B" modified="2020-06-17" version="1">MAQVARFLNSTSNPTCRLRRDLPVAVRFEALLNPGPAPGSLCLCFSPTRPSDARRTEAPSACGMSAPPTGRTRSIRRLPLPHEPGRSPLSAAGESDCPKREKERERQDVAVQCGGARSAVINGPCPRSRRLRWRLTYGARTVVPRKATLHAYLRGTPHQAACSRYGWSGDRIDPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA28</accession>
    <name>A0A6A6PA28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_333367</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA28"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097435">
        <property type="term" value="P:supramolecular fiber organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000003">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000009">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="17">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="432"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2460774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="447" mass="49764" checksum="C651B1C6E12D33B8" modified="2020-06-17" version="1">MREIVHLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGTSDLQLERMNVYFNEASGNKFVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLNNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAYSFRAVTVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVSMKEVEDQMRNVQSKNSSYFVEWIPNNVQTALCSIPPRGLKMSSTFVGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEASVSEGEEEYDEEAPLEAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA61</accession>
    <name>A0A6A6PA61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_369625</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA61"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="759"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="253"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="433"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="596"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="612"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="688"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="727"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="762"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="775"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="780"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="786"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="789"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="804"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="807"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="761"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="772"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="776"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="819" mass="85882" checksum="52ED8BD6973CD565" modified="2020-06-17" version="1">MATTTTSQQQRRQSARQARASTTRPANYYARTFTGRGSILGAASDGAGGAGAGAGGSSGQQQQQPGFYPAITHFTDSVAALPKEVMRHFSMLKEVESKICWPEEELKRLFESVEQMPAPPRRSHPSQAQRQQQQLSHGYNNAISAGDGASTLGGSMINGTMPSFDGVADGSAAASQNQEDMVDSMYRHQFGSMRNVLREALAALDEKNAVQSTACQTLEKGLVRMDSSYAHLDEEISEEARYGSTTHWAYHDKEPRKVVTNERSRRDAAHTNHTGASGAAHDEAASRSEARREAMLANKRSRAAAQHHHHDSDFEQQKKTATNSRARKVMEAADKTLGLGIANGPQPTKKRKTEKAASAAGAAGSGDVPMERTLSSNLNNTKGTAASPRATPGTDAPAPKKRPRAAPTQVLSSRKKNQAASGAQSPPVAPSPLLSTFTASKDTQQRPQSSRARQNSATNAPSAPTVVNAASDASRARPSSSASNRPANGIAAPPQQQETKPKVSNVADPSPDARNTPAETKETPENTALTTNGPVIEQQQPKMETEEPTEPAPNTDQPMPDVDSTNATTTTITTRAGRASKTATPLTATFPEVPMSRSRSTRNNNSGKDNNAGGGGGTAAGSTGGGERGDRGGDRGGDRGGGGGTASHASSESSVPISSTVAKRGAKKASGGDAAKDHAASTTTEKGTAAHHERPSSGRPKREGHGNNGGGGGAAAASGAVATEDGGVEKGRKGAKEERRSADGVVGVEEVDADDQEEPLYCYCNQVSFGQMLACDNETCPKEWFHLECTGMARPPSSKTKWYCDLCRETAKKGRPGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM3</accession>
    <name>A0A6A6PBM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Survival Motor Neuron Gemin2-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_85064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMN family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM3"/>
    <dbReference type="OrthoDB" id="197400at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22851">
        <property type="entry name" value="SMN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040424">
        <property type="entry name" value="Smn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39267:SF1">
        <property type="entry name" value="SURVIVAL MOTOR NEURON PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39267">
        <property type="entry name" value="SURVIVAL MOTOR NEURON-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="194" mass="21430" checksum="CE27BDB01637BA8A" modified="2020-06-17" version="1">MASVDSLYEQDDWDDSVLVNAWDDALQEYKRHRSLHAGGETFEDALAQEALRELALELGEYSDYKSTDEENEDGEGDEDEDEDEDEEMDDNDWYDEHDGEEQSQSENVNGIAADPTEKNVASQGSTEQAQQGAAETEFGTVAAGINGAPHAVLADGHDDNVPNMAMSWYWAGYYKGLYEGQAYGKCRHGAAQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBR7</accession>
    <name>A0A6A6PBR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_360499</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBR7"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF8">
        <property type="entry name" value="CYTOCHROME P450 2E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025502419" evidence="6">
        <location>
            <begin position="18"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="604" mass="68910" checksum="7B7886E6A8906A3B" modified="2020-06-17" version="1">MAFLSFAFAVALLCVFALWKRSQKQKKTPDGFKELPGPKGWPVLGSVPEVPEQNSFLKFHEWGLKYGKIYQVDLAGTNHVWISSDEIARDLLSKKGAIYSDRPHIPALIDDNRTSAQYLPLLSKNDGWQRQRKFANVIMRESEKADFHHYPELEAKRMLVELMNDPSKYNHSLESFVARVTCRLAWGHSEASEELKQRARELLISVSPTGALGNKLPFVMSLPDWLSPAKAWERKRAKTERRFFEIMQAQVQGDMKGKRAPHSWMRTFLENPTGWNFTYELEGAYSVGMHGIAGALTIAAPMQTFCLAMCHYPQYQSMLHEELDRVCGDRLPESSDRPNLPVLRAFIRECFRWRPPVPTGIPHFLTEDDTWNGYFIPKGSVMHPLEYSISRDPDIFPDGDSFNPNRWLDPKYPSYKEPLTQYPTILNCTQFGYGRRICQGQGVAEVDLLVSIASIAWLFKIQRNEEPTPEPETTNGMYGNEKATISIEELNAGFMPPPAPSQPHPYNGTDGSPIPSSCPGAYILGPEDEIKEKPKKKKIDPTHDYTKLLIAKPYPFTFNLEVRNHARAEIVKNEFVKCRADGKYEDPKTYWKEGGELGWVPVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC05</accession>
    <name>A0A6A6PC05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Voltage-gated hydrogen channel 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Hydrogen voltage-gated channel 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_332313</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC05"/>
    <dbReference type="OrthoDB" id="427456at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030171">
        <property type="term" value="F:voltage-gated proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="72"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="24464" checksum="ECF6D193F15A8B2A" modified="2020-06-17" version="1">MVDREASQPLLRKRRSLTAHFGQPVPPSWRESAQSRAQASREHVRFFLTSKAGHYSILLLVGLDVTCIFADFVITIFTCKGDVLDPIWNQVLEALGIVSLSFSCLFMAELLASVWAFGFEYFKSKFHCFDAIVIVAGFIVDVLTTGPIEEVASLIVILRLWRVVKIIEELSVGAEEEMEDLQSRAETLEKENKELRQKVEELKKNTQGDVLSSPTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC60</accession>
    <name>A0A6A6PC60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_278268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC60"/>
    <dbReference type="OrthoDB" id="4153866at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="289" mass="31756" checksum="90475F641924FBE2" modified="2020-06-17" version="1" fragment="single">LSRDVRPIPCHSHNDYWRSAPLFDALAAGCTSVEADVWLTALDNTEKDLFVGHGTDALREDRTFRSLYVNPLVRMLEARNNDSGPNAGARGVFEMDASVPLVLAVDIKSSGPETFDRVREQLTPLREAGWLSHYDGSAGEVKPGPVVVVGTGETPFGRVVEDAKYRDVFFDAPLSSLGSKTDDEERAGERFSAANSYYASVDLPSAVGQVWFGGLTTGQINKVRGQIDEARNRGMKSRYWNTPGWPVGTRNRVWKTLLETGADVLNVDDVKGARWSNWAGCGRWALGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC91</accession>
    <name>A0A6A6PC91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Non-repetitive/WGA-negative nucleoporin C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_398266</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin Nup133 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103454at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037624">
        <property type="entry name" value="Nup133-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13405:SF11">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="10">
        <location>
            <begin position="126"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="9">
        <location>
            <begin position="666"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1197"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1430"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1434"/>
            <end position="1451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1451" mass="160637" checksum="100BA54A945D9293" modified="2020-06-17" version="1">MFSPDATLHGSASSRGGNPRRRQRRDSTDSARQAAPQRKRSKLSEETFAAPANGGIVEGGAGNGGPVVMMNGHAGGTTPRYEGSPGPGVDLSGAAAMLDVPMREKKGTPGAKRSSKGDGTTLLSKTGSYAVKLLPGMPEELRRSPSENYRASSITTRPYAVAFTHKQALVWDYTSPIFNPSTTYLDLPQPSKPTNVLPLGALVCTGPSAELGLVHILPTEGKITYWENLESAQSHHLFQERTESVNGDVGGVLSGETIVDLIEAGHAGYIALFSTGRLAQILLRDQQGRPSITTRILRSDGFDGPRGILSGFKSIFSTGWKKDIAGVVTRPSATKGQMEVLAATNSGVIQAWDIGWQGHQTFKGQADCQEDLLNPFRTIPAPENKSHHQEQLKVLDVALLPDRAPHDNTLRLSTARSVVRLLLLLSISGPGTLRYGLAEIDISGSKAQVGRVVHLHVVSDLHLTSAPQNATLLVPSPGHTAFVVLQHMVAIVSVIDRADSPDTQLLTDSGRHLEPYQDAIYFKDDEEVSFAGWGPELPKAKSDQSSCVIFTRGCGAVRILANRPSEDERVTAKSKMEQAIFFGSIPGNVLDFSRRPAIEFSQEEVEDAAWKLSCEIRDSRSDFVPKIMVSMDQHIQFRMNALLSLAAHVRRFYPPMSRATKWEMMFIAERLNAAAGVWKAYDTENQNRNPNDPAQRTLLDELIMMMTKKENPDVEIGEVDAVRHWFARSIRHMDWLVPWSINAIKEILHHKGKDYRLLLPLISQGCDMMIAIMENAYAFRYEHKDTFGLQDEPVQQDGVLAYYAFEGLPEPWTCNYNVVKAFNTGTGISRAIVLEPANLTPEDAEAWDPATDPVLRNVVEDSARMLKIFCRVTVERYYWLVAQPDNTKKRAADDLANEFIRHQRYVHTMGMLEMGMFDQACEVAEKYKDMRLLVDIFMNQRTWVMREKAQAEQGQFGSAVVQSVEVQKCLDNLSRRLKRYFTDFGEEWSAAFYRKHVRSNALGSLLEMSSVDQEGVTRFLRSNAQLARTAWVNEVLVEHDFGAAADCLTRVASQQETNLWCEKVELSVAKLANLAAAKHRLMRPSDADARCAGGNGAWPSEPARRKLHARLGRELGLASLQERVFLHIRPVMMTAIDEDARVPVVMNAFGQERAAAGQGRLEELLRQGVAELCNQSVMSTWSLVDLLTLIDQRPSRGEAPAARARRGRKTWDGKGKTGAGAAGAGAEDICGKEFYLALEALRMSGEDAEMTRDLMLRLVWKRCFVKDDWQAINETQRKTDGSVGESLRATVLYETVRAVVEGGVLEDKSNYTVRFLSPEEVVGAGSSQKDIRVRFPAEDLSSEIVKDNMVDDARLQHYTAKCQLHHWWQHTIELARKDKESDRERESEETKTMAHMLGVGEKKVGRMVNGTRPARPARGASVVVAAAATAAAEAAERGGRPSADKDVEMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCL3</accession>
    <name>A0A6A6PCL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCL3"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="59307" checksum="B84FC6B96C52F55D" modified="2020-06-17" version="1">MERRTPSPNMSARDMQAQTLDRGAKKLVNEYKSTSHSNPGLLESAIADVRQALALCPAGHPRHAAYLNHLSTYVGLKYETSNKDVALMDEAITLMERAISQTDPSDCGLYGRRLNDLGTLHSRKYEATSNPTDFHAAIRHYTAAIEHHEEDEDDRGYARAAHNLATVHLRRFQREKSVEDIDAAVSWAQRAVDATDDEEQQALWLTRVEQAGDLLEVKYDVTRDLEALHGAIAQSVLLYEAFPPPEPHYWDGSTTFADPVFEAESDVDQRNARRQFVLGRRVWNLHVSGGQYENVGWAEGIEHMRSGAERTFKETRERRQRLDAFHKALETVEQSSGILSPLNSVIDETRTALAALPEETLDSPSAERADLLEKLALAFDERFKRRMIIDDASDALRLILESCEATPSSNDERWKLAKRLYHRARMLEWFFVEKDLPDYLDDGLGCARKALENVPEHHSELKGDILECLGRLLMSQYEEDYDEDNREEALSMMMQALELAPEGSEDRRVRAATLQSDPFQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD53</accession>
    <name>A0A6A6PD53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD53"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF8">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="28348" checksum="085E1067669AF6CE" modified="2020-06-17" version="1">MAPPTTLPTVLLVPGAWHQPVHYSKLISSLERLGFPTAATKLDSVGSLDPKNVTLARDIEYIREQALKPLLDEGRDVILLMHSFGGIEGSGAAKGLSKAEREVEGKKGGVVGMIWLAGLIMKEGDIWQDKSPVAKDPRLQVDEEAGVVYITDPRSIFYHGVSERDANSAVTLLLPMAVGARTTPSPAQAWADKVFEGRLGYIRCGSDKMLAPALQDRHMESTGLPWEVRTVEEGGHSAFYTHPGEIAKYVLDLTKTFTSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD86</accession>
    <name>A0A6A6PD86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDY21DRAFT_640</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="18">Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sterol desaturase family. SCS7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD86"/>
    <dbReference type="OrthoDB" id="2204368at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080132">
        <property type="term" value="F:fatty acid 2-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863:SF1">
        <property type="entry name" value="FATTY ACID 2-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="FATTY ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005149">
        <property type="entry name" value="IPC-B_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 19" id="KW-0349">Heme</keyword>
    <keyword evidence="14 19" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 18" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="22">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="19">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="19">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR005149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR005149-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF2461769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="402" mass="45564" checksum="519F345802858986" modified="2020-06-17" version="1">MPGRTLPTIPAVEIAAHDNKRSCYVTVGTKVYDVTSFLSDHPGGADLILEHAGKDVTDIMQDELSHTHTEAAYEILDECLVGFLATQRVLDTATKSERPDGVVPLPPSAKGAQELKANGVAPDVRGAAEEPVYAATGMSSEDDLSRPTDAASDYNKHKFLDLDKPLLMQVWNGGFSKDFYLEQVHRPRHYRGGDSAPLFGNFLEPLSLTPWWVVPTVWLPPVAYGTWLAGQGLPSAFHLVAYWLSGLFIWTLVEYGLHRFLFHIDYYLPDNRVGITLHFLLHGVHHYLPMDKYRLVMPPTLFLVLATPFWKLAHAVFYYNWYAATAVYCGGIFGYICYDMTHYFLHHRNLPYYYRQLKKYHLQHHFADFQNGFGVTSRLWDRVFGTELQLPSPPSSKVVKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDA6</accession>
    <name>A0A6A6PDA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_330139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDA6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="16004" checksum="E24E078509B1EF77" modified="2020-06-17" version="1">MMFSLASDKAWRLVCGVLLLSAGAAWRSVREASLRLASDADVSGSTERRPTSLLPTLALCCRGDGVRSKSKSPSGRSLDLPLMSGVIFSGSAIETALVAPDLGERASSGAALASSAAAAPSSTGAASGVTAATTPLSVGWSSVFASMACAQRTIRRGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDB3</accession>
    <name>A0A6A6PDB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_359844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDB3"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12283">
        <property type="entry name" value="RRM1_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12284">
        <property type="entry name" value="RRM2_RBM23_RBM39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000876">
        <property type="entry name" value="RNA splicing factor (Pad-1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000172">
        <property type="entry name" value="RNA splicing factor Pad-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="200"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="299"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="485"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="461"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="595" mass="67798" checksum="208C5A9037CFB3BC" modified="2020-06-17" version="1">MPNFDVEALLDQTAKAAVQGRKDIEGAAKDDRIKIRGRGGRDVDSNASLKSPADDDYSTRNRARTRSRDSDRRPRRDRDRDRDRNRERDRERERDRERDRNRERDRDRDRDRARHSRRDSEDSHRYSRGDYYSGTGRPRTRSRSPDDDRHYRPHGRSRRDDDRDRDHYRERDQSRRSSGREKRRDSPSPMEPSVDERDSRTIFVQQLAARLRTRELAEFFERVGEVNEAQIVKDRVSGRSKGVGYVEFKNEESVPAAIQLTGQRLLGIPIIAQLTEAEKNRQNRASENARSNSTSVPFHRLYVGNIHFNITENDLRNVFQPFGDLEFVQLQTDDTGRSRGYGFVQFRNPDAAKLALEKMNGFDLAGRPIRVGLGNDKFTPESTASLLHRFGGDGQQYQGSAFSGSGGRGVHAGGSSNGFDRANGRDNEKSTSASALDDSDMAGVNFNNYSREALMKKLARMDTDDQPSKNQAPKPKTGKPANDAKSSLLANVPVASRCIRLRYMFDPAEEEGEDWVKELEDDVKTECEAKYGKVVHIAVQPHSEMGEIYVKFDRIEGGENAVKGLNGRYFGGRMITAEYIVDAIYSSVFSRSRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDH3</accession>
    <name>A0A6A6PDH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_87193</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="3"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDH3"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="14547" checksum="3227DE3381CBD5F2" modified="2020-06-17" version="1">MRSGGAAANGASGAKSGILESVAGWAGFGGKGGSNTAETMTEEGESEPYDLLIIGGGATGSGIVLDAATRGLKVAVVERDDFSSGTSSKSTKLVHGGVRYLEKAVWELDYNQWVAFRVPMVRKFRTELIRFNLSGTRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDU2</accession>
    <name>A0A6A6PDU2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_8096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDU2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025541299" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11491" checksum="6A8538916327F9AD" modified="2020-06-17" version="1">MPAYSYFMLRLRLFALAAIGAARFPHPADLYNHVPPPLPISPISLGRRPARGEAILEANSKPPHSAPLSHCCQIGRKANKRTPSARAQHFFVQATQLGLYLVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE03</accession>
    <name>A0A6A6PE03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_368190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE03"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="31516" checksum="FD98184A3D7604A6" modified="2020-06-17" version="1">MASTRQHRRGLASEAAISHKNSTTSSNISTNVADSPLTRHVTYSGVWHPPTTAPTDTVIATAYRFPMMIPERFVAYSASHLHLPLRRDILHRAIVYEGDKTRQGTASSKHRTELAGSGRKIRPQKGMGMARLGDRKSPMLKGGGVAHGPHPRDFSTDLPRKVYDLAWRTALSYRFRRGQLVLVDGKAELWSAQGAFVRNVFSTNGWGRAAGRSLVITMEKRPNLFSGLQAAPRMGEAYTWNDVDVKDLLSMGRLIIEKEALDKILKRHQSDLTKTYKIVTTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PG63</accession>
    <name>A0A6A6PG63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquinol-cytochrome-c reductase complex subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_12996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PG63"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="170" mass="19279" checksum="108A024B6A5388BE" modified="2020-06-17" version="1">MPWCKQWASVDLFSNAQASPRHLSVYPPHLTADFRQLYLPDKPPLPASYGLFSLYIQQNYLFMAMPRAILRLRPTTSMFSNARPLMMRRSYTAYQSPHGPKYKIQRNIDGITLGSARAYGQIAAGMGGVVAFFALFFFAEVPRVAKDIMQKVPVIGPMFEKEVPPEDNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL94</accession>
    <name>A0A6A6NL94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_294661</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL94"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="174"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="395"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="536"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="590"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2452436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="600" mass="66919" checksum="4DF1508F3EF26819" modified="2020-06-17" version="1">MGSEGARSEDRFSAHSGGAAAGSESSPEPVGGAFEAPTYEKKEVTYDQVRSLGWVPPAKYDYSVYMTDHSTRNDLVEEGKEPKWLSQAARYEWDDEYGDVGPHDEKLEDELFRSMFINRIGNKMDAYEYRVNIQGPQDVAPVRRFIDAGLHPVMLENVHNCGYDVPTPVQAYCIPAVLLGHDVVATAQTGSGKTAAYLIPILSRLMGKAGKVCGPKAGINGAQYPVRAEPIVVIVTPTRELTIQIFNECRRLCYRTKLRPCVIYGGVPARVQADDLRRGCDVLVATPGRLIDFMEKANTLSLNRCKFTVLDEADELLHTDWEPEMKKIMRGATNVQDDDHTYMMFSATFNKTCRKVAKEYMSEDRIRVTIGREGSTHKNISQQVIWTNEDQKRNALVDLLLSLPPARTLIFVNSRRTADLLDDFLYNQTFPCTSIHYDRTQLEREEALTKFRDGSTPILIATGISARGIDVCNCMHVINYDLPAADRGGIDEYIHRIGRTARIGNEGLATSFYNDKNEDIADKLVKILVENDKPVPDFLQQYTPQEGDKLDFDDESLPSSDEDEFGQSPNDNGSTAGSGVAAPEWKAPSDSDDDNANVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMP3</accession>
    <name>A0A6A6NMP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Gamma-tubulin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_388325</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Spindle pole body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMP3"/>
    <dbReference type="OrthoDB" id="10249382at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08570">
        <property type="entry name" value="GDPD_YPL206cp_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000004">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000003">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000012">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="11">
        <location>
            <begin position="60"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="708"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="728" mass="81088" checksum="79C99B328DA2DE78" modified="2020-06-17" version="1">MSDSGEPTAETPLVENMAVPAFIATADRGEVNDPLLPARRTFSMPAFTRARIDKLGRHMPQTIAHRGYKSKYPENTMGAFAGAADIGAHAIETDIHLSRDGVVVLSHDATLKRCFGQPGKIVDYDWEYLGTLRTAKEPHLPMPRLLDLLKYLARPENKHLWVLLDIKIDNDPDDVMRLIAATIAQVPPAKGRPWAERILLGCWAASYLPLCDKYLPDFPITYIGYSLSYASQFFVTPNVCFNMLQAVLVGPFGARFLHQARRLGRAVEIITLQAGQCGNSVGSQFWQQLCQEHGISQDGNLEDFATEGGDRKDVFFYQSDDTRYIPRAILLDLEPRVLNGIQTGPYKNIYNPENFYIHRDGTGAGNNWAAGYATGEQVHEEVIDMIDREADGSDSLEGFMLLHSIAGGTGSGLGSYLLERLNDRFPKKLIQTYSVFPDTQNAGDVVVQPYNSLLAMRRLTQNADSVVVLDNGALSRIAADRLHVQEPSFQQTNQLVSTVMCASTTTLRYPGYMHNDLVGIVASLIPTPRCHFLMTSYTPFTGDNVEQAKTVRKTTVLDVMRRLLQPKNRMVSTNPSKKSCYISILNIIQGEAEAQDVHKSLLRIRERRLATFIPWGPASIQVALTRKSPYVSSSHRVSGLMLANHTGIATLFKRITFQYDRLRKRNAFLEQYKREAPFSDGLSEFDEARAVVQDLIHEYEDAEEADYLTKDMDKEDGDGQAAGGAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMV6</accession>
    <name>A0A6A6NMV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_146022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMV6"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="144" mass="15960" checksum="C8B8CF37126E2637" modified="2020-06-17" version="1">MQLAELFKEMVIAIKAAPGSTSTQPTDTATAHSEELRARASRLEYKTVREVWNPSAYRYRIVEDTVQASATNELDEYVDITCGGRSHVTLGAVYRRVQVHLHSATSTSYALCLPPYTLWSSTPRPSKYGSWGGDFTSPSTQEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW7</accession>
    <name>A0A6A6NMW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="126" mass="14141" checksum="6EEC38DD8EC4328A" modified="2020-06-17" version="1">MHAEQMPKDTPSSPTHSRQTRNRKTRQTALVSPCKRLTEHPQPWKLGPSPGTPPPRAQNPSCRNYGWTACTRSVMVGCQCRTKRVLLEGLLGDDPREDPRCTYLRIGVGRIGIGRVDGRWRGRGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN36</accession>
    <name>A0A6A6NN36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_357348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN36"/>
    <dbReference type="OrthoDB" id="2156052at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052396">
        <property type="entry name" value="Meiotic_Drive_Suppr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="567"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="779" mass="88056" checksum="AA6E55461352C3E2" modified="2020-06-17" version="1">MDEISKLQRLLEESERRREEAESRALEDRRRREEAESRALEDRSRALEDRRRREEAEELSKASQPRTLQHYLDACHSLNLAIQVVTDPSLTTQGDTTNPTGRIFPRRIIPWDDFPTKQEKIWDQLSIGDLFSSQAAFPSQHQLDYVNSLLQPISSELGLRDFERDVVENAVRKLVEQAYNDLLLRSSLGLQGIVSFESHTNLGNVDDPISESMEQMSIGETGSGATVSVQRRSGPKAHHKAKGKGNRADQFCVYRTSDGRNVPVLAIEYKAPHKLTIDEVITGLESEIQPERDVINKDGEGFAFAAKALTAAVVTQLFSYMIGKSIQYGYVCTGEAFVFLHIPDNPTIVYYYVCVPNLDVLDDDETRLHRTAAAQVFAFVLQALRAAPPPMSWHDEAKSLDTWVVEFDDVLSKIPATVRKEARSTPYKAQRWQGFKRSPIRTRSYCQQLLGNVKHRGDDDDEEGPPSPTPGRSTRSGKKAVTSSTATGSDQKRGQRSGGNRRQGQTTQQTIHSRPFCTQKCILGLAYGGPMDTNCPNFDDHGQRHIDRLEFLRLIRTQLATDRGRDADCMPLYLSGSLGSLFKVRLSSHGYVLVAKGMERFYLGRLRHENELYDRLRALQGKHVPVCLGRVDLILPYYYDGGVFEHFMFLSWAGRPVFKCINQLSQPGVVDAVTTAFKELHTLGVLHCDAEPRNILYDADRSNLMVVDFERAKFYDRQPLGSISPNGQKRRGKRGMLQKQEKDDMSQKQEKDDFAQELQFAVDSVSRCFGRGSCPDKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN43</accession>
    <name>A0A6A6NN43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_293516</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN43"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000006">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000746">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF81">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="9">
        <location>
            <begin position="8"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="10">
        <location>
            <begin position="183"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="34474" checksum="08BC13E723977EC7" modified="2020-06-17" version="1">MALLTYSTVGFVGLGAMGRPMVEHLANKLPETTRIYVFDVVQAAIDQLCEKYPGRILKGSDAKDVAQKAEIIITMVPEGSHVRSVYLDSTHGICATDINGKLLIDCSTIDTATSLAVKDHIATRFATASFYDAPVSGGVVGAIDGTIAFFLGCHPTDANLARLTALLSLMGGKVIPCGGPSLGLAAKLSNNYLSGIIAIACSEAMDMGMRSGLDPRVLAQVFAAGTAQNTICDRFNPVPGVFAKAPSSNGYREGFKVQLMRKDFNLAVEMAKRVGSKNVLGGAGLETYTGAMNDPRCRDLDSRVVYRYLGGNEEWQKDHPNGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNK1</accession>
    <name>A0A6A6NNK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase complex subunit H-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNK1"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019711">
        <property type="entry name" value="ATP_synth_F0_suH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10775">
        <property type="entry name" value="ATP_sub_h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="135" mass="14645" checksum="141B4EF032C9795D" modified="2020-06-17" version="1">MLSHAIRASRSNSAAAVARVAARRVGVTSRRSLFVPSAVRQADLVQDMYLRELKNYKPPPVKPGDAEAHVHKFSPPKPPPSPEEADMAAELGAYEKQAVELEGQADQGKGGEEGAAPVEDWLEEPAEEEEEEGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP61</accession>
    <name>A0A6A6NP61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_355978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP61"/>
    <dbReference type="OrthoDB" id="5592486at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20640" checksum="A9F66CE7C8C02779" modified="2020-06-17" version="1">MISRLQPKNIDILSLTTIATPHRGSAFADYMFDQIGPKHVPRVYRTLESVGFQTGAFGQLTRAYMRDEFNPRTPDQLGVRYYSYGASLDPTLWSVFKFSHDVISRLEESENDGLVSVESSRWGEYKGTLVGVSHLDLINWTNRIKSLVWRSMGWEVNFNALALYLDIAGKSIPSSIEGLRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQH9</accession>
    <name>A0A6A6NQH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_123921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQH9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="57" mass="6401" checksum="ED2B37D3332FD9F2" modified="2020-06-17" version="1">MHYFGVFFERCGAVVFVIPSFNMWLVMAGRFGRACFLFLSRCVLSGAPIIVYMGVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQJ4</accession>
    <name>A0A6A6NQJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_292639</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQJ4"/>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="282"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="324"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="612"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="740" mass="80302" checksum="A302590BE5402D1B" modified="2020-06-17" version="1">MAEQEQRIPAHPPESEGSEQLASSPMGPPSSTGSRKPKKPPPITPKRFNRFFTPRSSTGQRGASVSGKSGRQLRDITKNASNRLIGAQSATSSSTSKSILFDDIPTRYDNESSQTPHIGSSKKRKGLLSPESSPIPPSPSKKPRCDNASPHQGIHIIHEDDFRQSSSIESSLEPEDVAFPRPIRKVNGLGSAGRILQRSFGGFNGLGRGYRVDHCSDGCRQTRDFYTGQDDCHIYSDKQLPFCVASCNTNSLVAIGDEEGSINVIETRPDEDALVIQSHVIFRPHQNAVMDMAFSSDDYVLATASGDQSCRVIDMLTQTTKYVLAGHTSSVKQIRFQPGNNNVLASSSRDGSVQLWDLRCRGTDGPTIDVHVPLGLGSTNPPVYNETRATYANIYNSIVGAHTDRQVTTSTLSSSTLNNAQSRDNGTKGELTTRRSGEVSITALSFLPVGREHLLLTASEASTSIKVWDIRGRYSSRRGGPVPISTTHQPESHSRHRQFGINSLALSSDTARLYALSRDSTVYAYATNHLILGQAPEFGPDRNRRHRYGGVGESKEGLGPLYGFRHPLFHATTFYVKASLRPAREDCPELLAVGSSDGCPVLFPTDERMFPQTDGDDDDREPRVPTVGGWPIPPRRTASAAGLGPASRLEDTIPIYHHGTPLVHGHVKEVTSSAWTHGGELVTVGDDYLVRCWRQDGAKAEKLRRAGQTGEGAMVRWGCGWAQGGEGGAGLGEDGEDEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR01</accession>
    <name>A0A6A6NR01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peptidase S8/S53 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_374373</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR01"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019863">
        <property type="term" value="F:IgE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.80:FF:000006">
        <property type="entry name" value="Autophagic serine protease Alp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025456746" evidence="9">
        <location>
            <begin position="18"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="11">
        <location>
            <begin position="45"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="175"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2454161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="549" mass="59205" checksum="947974DEBFDEF87F" modified="2020-06-17" version="1">MKVVALLTPLLATLASASPVLYVDSVRQDIAPLVSSTNAQEVPDSYLVVFHKHVDQAKARVHHDWVQNLHLNNQAQRTELRKRSEYPLVDSVFEGLKHTYNVAGGMMGYAGHFDEDVIDQIRRHPDVDYVERDSEVRTMEGTTENNAPWGLARISHRHSLSFGTFNKYLYSEDGGDGVDVYIIDTGTNIEHVDFEGRASWGKTIPANDEDVDGNGHGTHCSGTVAGKKYGVAKKAHIKAVKVLRSNGSGTMSDVVKGVEYAAEQHSQAVEAAKKGKGRKGFKGSAANMSLGGGKSVTLDLAVNAAVDAGLHFAVAAGNDNADSCNYSPAAAEKAITVGATTLADERAYFSNYGPCNDIFAPGLNILSSWIGSKYAYKKISGTSMASPHIAGLVAYMLSLQPAQDSSYAVADITPEKLKANLMNIATEGALTDVPSNTANILAWNGGGSSNYTDIINKGGFDVSADLMDEVWAQPIDDVEDDTVTITIPDMDIQIPSTETIEVEIESAAQNARPAADRFRERFENLKHEIQDFVADEMAELMGEAVEEMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR32</accession>
    <name>A0A6A6NR32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation factor G, mitochondrial</fullName>
            <shortName evidence="10">EF-Gmt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Elongation factor G 1, mitochondrial</fullName>
            <shortName evidence="10">mEF-G 1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Elongation factor G1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MEF1</name>
        <name evidence="12" type="ORF">BDY21DRAFT_387810</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR32"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04097">
        <property type="entry name" value="mtEFG1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04091">
        <property type="entry name" value="mtEFG1_II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000022">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000015">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000558">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009381">
        <property type="entry name" value="PRK12740.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636:SF2">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="55"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="141"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="195"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="757" mass="84190" checksum="B9414068EAD426E7" modified="2020-06-17" version="1">MGVDTGVIARGDALRRRWQSGAAAAVLEQAKEDPATLSQDTIVENLDPREAARLSQVRNIGIAAHIDSGKTTATERVLFYTGRIKSIHEVRGKDAVGAKMDSMDLEREKGITIQSAATFCDWVKKNDQTGEEEKYHINLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFINKMDRMGANPFKAIDMINQKLRIPAAAIQVPIGAEDEFKGVVDLLRMKAIYNKGPRGEHIVEKDEIPADLKDLVAERRAKLIETLADVDDEIAEIFLDERTPTMEQIKAAIRRATVSLKFTPVLMGSALADKSVQPMLDAVCDYLPNPSEVENLALDRRRDEAKVKLVSYNSLPFVGLAFKLEESNFGQLTYIRVYQGSLRKGMMVYNARTDKKVKIPRIVRMHSNEMEEIPEIGAGEICAVFGVDCASGDTFTDGQLGYSMTSMFVPEPVISLSIKPKTTKDTANFSKAINRFQREDPTFRVHFDPESEQTIISGMGELHLDIYVERMRREYKVDCVTGQPQVAYRETITKKVDFDHLLKKQTGGAGDYARVVGYMEPTGQLTANRFTQNVVGGAIPEKFLSACDKGFHLACQRGPLLGHKVLGTHMNVFDGQTHMTDSSDFAFSMAIQQAFRKAFKQGAPVVLEPLMRTIITAPSEFQGNVVGLLNKRNAVISDTEVGAEDFTVTADCSLNAMFGFSTLLRASTQGKGEFSMEFSHYAPAPMQLQKELIAKYEKEQAERNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR62</accession>
    <name>A0A6A6NR62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_107308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR62"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17464" checksum="ED3AC6E46C525B5C" modified="2020-06-17" version="1">MWPNFSSKPYVLERRRSKKLHDPCGSVGSARGILALPDGQPRHTRYTLAVKIYRGGSRRGPSIRAKLGKSVSKTTCRSLQHLRPDLYWARTPNLPKTSTLLHEVTPSESHWILQPGNNLRYLASDNWTAPSELASVSPLTFTTSSIWNISASDIHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRC8</accession>
    <name>A0A6A6NRC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_108737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRC8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="130" mass="14095" checksum="BEC79E303BC92CAC" modified="2020-06-17" version="1">MCNGNSPRLNIGGLVATLHRPELNNGVRLDIPSRLTFRNPGDAAGCKRTEMSVEWEAALASKDGNLGNSNNVEDPLYSFHIRQPTTILEEVLSFDVGGDGVVGRRVSIVKRTGFGVPKHRTIAEGIIGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ2</accession>
    <name>A0A6A6NRQ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldo-keto reductase family 1 member C13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_291385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ2"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="295" mass="33208" checksum="2BA47CC5CAA44DB3" modified="2020-06-17" version="1">MANLQTTMPSLKLNDGHSIPMLGFGTGTAWYKRSEGGLDRDLIDAIKTSLKLGYYHQDCAEVYCTEQEVGIAIKESSVPREKLFVTTKVYRELNDIEGSLKASLKKLQLDYVDLYLIHSPFKFKSDEELQQAWATMESLREAGLAKSIGVSNYLPQHLEKLMKTAKVTPACNQIEFHPYLQHGPLLDVHKKLGIATAAYGPLTAVSKARPGPVDDLYAKLAKKYAVTESEIALRWCIDQDVVAITTSGKEQRMSDYMRALAFKLNPAEIKEIKELGEEKHFRGFWKAQFAEDDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS21</accession>
    <name>A0A6A6NS21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_105703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS21"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19611" checksum="5E9269EA303F1849" modified="2020-06-17" version="1">MRARRVRAPCLCGQRLRRQTPSQDGVLPASQGAKEWPWLRQACGMCKWARRTCATTSRNTYPLRPVVPTASLHPSPIQPRRSFSPATGASARWRLIVRCPNGAGRIPRPARGRPAAHGQSLGRSCAYVLSDWLAPASVETRPQHRCHALSLFYTHPPAPLTSSPFHQLNPPQASSPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS24</accession>
    <name>A0A6A6NS24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_423772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS24"/>
    <dbReference type="OrthoDB" id="3783344at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="21222" checksum="629411132C8C69F4" modified="2020-06-17" version="1">MATAEPKATIALFVDAARSGRADELRHLFESHSDYRTIIPGWRLFDVHYLAFFAGVETWKVVVEYVLEAKTWDLGEKGDLIGGAALNNDLPMMQYLLDELHLNANEGRIMFTPVLMMIDPDEEIKRKAWAGEDEKRSTVRAEIVKLLKSHGCTMGGQGEYAQKSHMLGSGKLCWHRVGKTKSSCPVVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI0</accession>
    <name>A0A6A6NTI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI0"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="247" mass="24404" checksum="220176EEA5B4E47A" modified="2020-06-17" version="1">METDGSGHAAGGSGSGSASTSTGSHAPPSLPARFSLSGHPGSPSVGSSTDGGQAEEPLELEAVVSCTSDGLVVCLRRAHPPKPPSLPAPPQPPEPAFRHVGGFFAAPWALEPQRNLGAAFGPPYGGIAAGPAGGPMADYGFGNNPAVVAMRAAEQRAKDEAVMRAIRDTAVFAWGLTGINGTLVNYSRGHPGGESQPPSGFPVWASDSRASGTPADSGIAVGGLSAAGEQPPFGDPGMGGSRSGTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTJ7</accession>
    <name>A0A6A6NTJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_290759</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTJ7"/>
    <dbReference type="OrthoDB" id="627829at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="176"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="366" mass="40664" checksum="5FC86B1D9D159E5C" modified="2020-06-17" version="1">MSAFSSIPNLSLAAARAAETKPGFLAALRAALLDVGFLYLSDTGLPAALVAAAAAQARAFFERLPAPEKARIEMKNQRSFLGWSRLNNETTAFKLDYREQLDLSTSHPIPGPEAPLYHNLLAPNQWPSEDHLPEFRPVFEEYMRRMSQISDFFTSLIAECLGLPADAFNRFFDADQQHKLKIVKYPESESGSDDPAERQGVGPHKDSMLTSYLLQASPQRGLQAQNADGDWIDVVPLEGTLVVAIGQGMEALTGGVCASTTHRVLSPKRGEGVRYSIPFFQGVSYDAKFEEMDVPDEVRKLRTESRGRRGGRKDDVEFTFVKGRWGHLGEATLVNRIKSHPDVGERWYPDLLADIRKQQAKDAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUM0</accession>
    <name>A0A6A6NUM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoA-transferase family III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_289307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUM0"/>
    <dbReference type="OrthoDB" id="16747at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1540.10:FF:000004">
        <property type="entry name" value="Probable alpha-methylacyl-CoA racemase mcr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050509">
        <property type="entry name" value="CoA-transferase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228:SF5">
        <property type="entry name" value="ALPHA-METHYLACYL-COA RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228">
        <property type="entry name" value="SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="400" mass="43078" checksum="75EE658247C7DF1C" modified="2020-06-17" version="1">MAFPPPLSDIRVLEFAGLAPGPFAGLLMADFGATVLRIDRPVPGAHSSDPPPPTPDLLVRRKSSIAVNLKSAAGAALVKSLIPSVDVVIDPFRPGVLERLGLGPRDLMKHNQRLVVGRVTGFRRDGKYSMMAGHDINYLAVSGVLSMLGRAGDKPYPPANILGDFAGGGAMCFMGIVLALLTREKTGMGQVVEANMVDGSAMLATMPRLGTKTRAWNQPRGKNQLDGGAPWYDTYETKDGRYMAVGAIEPQFFAAFLKGLSLSESDLPGDRWDSSTWPQMRDLFAGTFASKTRAEWEAIFDGTDACCTPVLTQAELEESGFDQRPAVTLRNSPALAIIDDAERPVLGQGNGVDGQGWSEKGLSPGCDGEELLGRWMGWFKERQYKVVNGGLELTQKPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUZ4</accession>
    <name>A0A6A6NUZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ceramidase</fullName>
            <ecNumber evidence="1">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_349603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.23" evidence="1"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUZ4"/>
    <dbReference type="OrthoDB" id="5273684at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029130">
        <property type="entry name" value="Acid_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583">
        <property type="entry name" value="ACID AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583:SF1">
        <property type="entry name" value="ACID CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15508">
        <property type="entry name" value="NAAA-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acid ceramidase N-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="51539" checksum="7E0FBE0B32C53057" modified="2020-06-17" version="1">MAKPPRYSVDMSVAPRDRYDAVARRFKAEIAHLPSLFAEVIEEFVLGLGQALGMRNGLPISAAVVIRVAKLVFRRMYSKEEEEELRGISERTGVGVSVLIAFNVLVDTFFGCSSGGARVRSKKGKSRMLHFRTLDWGMEGLRRMVVLLEFRERVGGDVVAQSVTYAGYVGVLTGVRKGLSISLNARPTHNNSHSFVANVRFYLHLLLVVFGRRPPISSIIRSYLVPTPTSSDSPSTASPTTDPATGTSSAIANEQSPTTVHPRRTSSTATAASTTSSAAPLILRLSPDSTVKPNADLPPRAAQSLLTILTTLPAIPTTAAYLILSNGHATAVMEKDLRDAVTRSSTSFVVCANHDEGMAELGQEGDSDGAAEKKVKMPERSWLANSASVGMEEILKESVSRAETIRRRWKRAVGNKKGVGTEKEREEMAGEGDVVRLVSKSPINEVGITHFAAVMDPDVGRVVWCRVRTDSVEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV78</accession>
    <name>A0A6A6NV78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="12">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_289124</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV78"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="344" mass="39269" checksum="B09C9A02A448D4BC" modified="2020-06-17" version="1">MAPPSWLQYGKPTLDRPFGVQLWPIFSAAFEPIVGYKPEEFRFVQGETPMSTLPTTAAMLIGYYILVFGGREFMKNREPIKLNGLFMIHNFYLTAISFCLLVLFAEQLIPTLTRNGVFYAICSYDGGWTDKLVILYYLNYLTKYLELIDTCFLFLKKKPLTFLHTYHHGATALLCYTQLVGHTSVSWVPITLNLTVHVVMYWYYFQSARGIRIWWKQYITVMQIIQFVVDLGFVYFASWTYFTSTYWPWLPNAGPCAGEEFAAFAGICILSSYLLLFISFYLATYNKPSVKGRGRAKSALVEMKDEKVPMVGEARRRLSGGSTALPNGHATPTATGRVTRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVH4</accession>
    <name>A0A6A6NVH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Anaphase promoting complex subunit 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_395925</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVH4"/>
    <dbReference type="OrthoDB" id="10262026at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007192">
        <property type="entry name" value="APC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF10">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04049">
        <property type="entry name" value="ANAPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cdc23" evidence="9">
        <location>
            <begin position="11"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="413"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="447"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="481"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="41"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="647" mass="72028" checksum="9F8F744C6D5A636F" modified="2020-06-17" version="1">MAGLSEDDSAQLQSHLQHAVISCSERCLYNSAKWAAELLNSLPTPSSNTSNADPFSSPPPPSTADSHDSSTAPPPPSTTPYPRPLPPSDPTQARLEAREANRFLLAKSFFDCREFDRCSAVFLPELVPRGPLPAASVPAAKPPGVRPAGLSMKALFLALYAKFLAGEKRKEEDSEIVLGPMDGGVAKNREVPTITKILQDWFEERHGSGLAGDGWLEFLYGIMLARSKDEDMAREWLVLSVHLNPWNWAAWLEIAGLLSNRCKQLNRLTEHLPQNIMTFIFHVYASQEFFQCTDQVHNSLTQIGAIFPGSAFLQTQRALLYYHSKDFEEAEAIFNGLLVADPHRLDHLDAYSNILYVMESRPKLAFLAHLATRVDKFRPETCIAVGNYYSLKSEHEKAVLYFRRALTLDRNFLSAWTLMGHEYVEMKNTHAAIESYRRAVDINRADYRAWYGLGQAYEMLDMHLYALFYYQRAAVLRPYDPKMWFALANCYAAVGRADNAIRAYKRALVAGSYSQTSGGAAPAAGSAMDGLTPGMLGILDPDALYQMGLLYEKLQRPAECAAYMRLCIAQEEGPSEADQGGAVGVGVTSSTSKARMWLARWEFLRGEWQAAMELANELCQDGVEVEDAKALVRDVRARIAMQEGRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW38</accession>
    <name>A0A6A6NW38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW38"/>
    <dbReference type="OrthoDB" id="3248508at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="47877" checksum="C8B9652C2C869330" modified="2020-06-17" version="1" fragment="single">RRRLLIIYIHGFMGDETSFRSFPAHVHNLVAITLAESHVVHTKIYPKYRSRKAIEVARDDFSRWLAPHESPNTDVILMGHSMGGLLSAEVVLLPPTGPAPPARAFQHRILGSINFDVPFLGMHPGVVSSGLASLFKPAGADDKAAGAGGQDATTASEALAAPAPPSRHDTLFAKPTHDPNFNPAFANDVRVPARKGWQSTLHFVAKHSDGLVRASKQYLKSHAEFGGAMADFGGLRRRYARLRALESDDPAARRRAVAGAWAPPAGAEDPPPPPRVRFVNYYTASSGRPKKPKQPHQHQQHDAPPPPPSPDVALAPQTRHLPVASLDSQATAADDADDDDDDSPAAATDSASTASESWVTLSPRPSTVATTKPRDRKFCLLPAKGADGGRDPAWTRVYMDGVDEVGAHCGLFFLSETYERLVGDVAARIEEWVGEEMSRRVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWF5</accession>
    <name>A0A6A6NWF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Endocytosis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_323080</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the END3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWF5"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025604">
        <property type="entry name" value="End3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF74">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN END3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12761">
        <property type="entry name" value="End3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="19">
        <location>
            <begin position="10"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="20">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="19">
        <location>
            <begin position="141"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2456066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="416" mass="46668" checksum="BED7F7B585CF27AB" modified="2020-06-17" version="1">MASKKIEEWEVQRYWEIFSSLVQGGTHLTGAQAATVLKNSQLRDDQLEKIWDLADVDNDGSLDFEEFCVAMRLIFDLVNGEYAEVPSTLPDWLIPESKAHLVQANRALSGQSDSFPRAPSPTDSDTPGLKDGFDWYMPPGDKAKYEEIWTANRSARGELYFDALEPLYESLDVPDTDIRSAWNLVNPQARPAIGKDAALAFLHVLAQRHEGYRIPRSVPPSLRATFNQGNIEYNVDRVGSPAGGRTAAQRWGTSSRDDATETGRKTKFGDAYLSRLGVGDRAHNRPRGTDFSGARTTEDWEEVRLKKQLRELEERIERAEKAKRGGADGSGGRRETKPALVKRELEMLLDYKRRELRKLDDSEKGGAGGGGKSLRSIREDIETVREQVQGLEAHLRSREGVLDDLKREIEVEKGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWF6</accession>
    <name>A0A6A6NWF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_54960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWF6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="32386" checksum="96985B121AB1123F" modified="2020-06-17" version="1">MYIRYLGTPVTVCPVKTREIIPYYLQEYHTSAGRFDVPDLDYDSRLIQEKIVRPQDMRFAFALLIDLLHPRNTSTIADLSLRVLDALDRKFIDDTTRRARTYSARRFDDCLVSFSRFPSSLGAFWSLAEISARYGSRMIVDCLIAFFQQHSKNICASETTAPRPYSHIHMLTMWGTAVATSFMTESSMFACLQEICRRLPRGYMPQRSWLDGEVPKWGLFVDEYGRMIRSMTNALREDVYVTTRIFRAKPRRRHRYPTACIDRIRQRACPGLSRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH6</accession>
    <name>A0A6A6NWH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_61484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="117" mass="13045" checksum="3E7471A838F14249" modified="2020-06-17" version="1">MIRTFSALLAVSFAVHISQDARHVAFLPLWPRRSLNRKPNTFPSLLEQVSPCGISLRVPNIARKAISPLASIPFCSFLSPVFRTRSCRLCTHAPSAPCSSYTTLSTLLRRIGHRPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH9</accession>
    <name>A0A6A6NWH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_347945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH9"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF121">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="32170" checksum="D7E7FF6A56B81E73" modified="2020-06-17" version="1">MTARFLRSHISPAAALSRTSDVGVRRAACNAAPRAFSTSNRRDKTAIVTGASRGIGAAISRRLASDGYNLVLNDIPVQSSALDGIASEITSSNPGRKAVPFVGDVSMVGDVERLVQASVDEFGSLETMVANAGIAQVKHSLDLTKEDWQRMFDVNVMGVFNCYQQAAKQMIKQGSGGKLLGAASIVAFKPFPCLNNYSASKFAVRGLTQCMAMELAEYKITANAYAPGIVGTAMWDLIDEKLGERSGRPKGETIKKFSQELIALGRTSVPEDVAKLVSFLASDDSEYVTGQTMVVDGGIIMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWN6</accession>
    <name>A0A6A6NWN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_288903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWN6"/>
    <dbReference type="OrthoDB" id="5352472at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="368" mass="40352" checksum="DFD1098DF0EFB769" modified="2020-06-17" version="1">MPIQLLPASAAAFAPRSAPTVVLNSKVEPWLTQTLKRINRIKRPLNSVPQHFRCLTETLSGANAIWSLCSIMVPKAPDSELRKDSNPLVEALFNYQLIHIEAYVVHVDMVSQHEVAFKLTQDTIDALVEYHKDIYCVDVAASTWNWAEKEVQLKKLQEEFVQAVNRYVFRTGVRALEGMEEEGAGELLDGRSEDVKNAIMGLFLPLLPPPPRIVDVVRPAPILPSSDNTAGGHWWQPTHSLPTQSLPTQSLPPPQPAPVESWRVLPSTPSPTIASQCTAESQQPSFWTTMADVPNMQLPSPTPSFSQPFSSSSDMYNSPTPSTAMPAAPLPLPSVLAQQCGPAAANNNFGGGFSWSYNDFAPQYAATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWV6</accession>
    <name>A0A6A6NWV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWV6"/>
    <dbReference type="OrthoDB" id="3877279at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="29532" checksum="8392F1DB817C2C58" modified="2020-06-17" version="1">MDTPQHAAVDRRASVDSFELDSYLANYVPLSNFPTPPPATSSFPPLRAAVAEDAVTSQAQDFGGPAIYMASLVPSKASLHGPSIALIQEFLARAQVPDEVIGLAACVLDSLSWRFVREWRQACSQSSSSAETWHNGGPGGTGAVGAEVIVLSALALAETYLSDEPRSSRWWSREVSSLSFSAKQINTTNRCILVDIDYGLHDFTAEMIDEMLWDMRRAERMLEKTGATTDNSLRSDKLAVTSLSLDCSATLVHGLLTPEPSPPLSQLQRSLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWW4</accession>
    <name>A0A6A6NWW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_323477</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWW4"/>
    <dbReference type="OrthoDB" id="7457040at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042171">
        <property type="term" value="F:lysophosphatidic acid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035965">
        <property type="term" value="P:cardiolipin acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="178"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="585" mass="63627" checksum="25A7CAD3AE5D9C71" modified="2020-06-17" version="1">MPSAEEEAQFRARPQHSPLASQRAREQREQEANREREQRQAGGRFANLFPLGYKDGFSQWWTSLKPAVAEHTVLSFVPHLQKPPTHAVTGSAPASCKTSKTNLTAQGQDAADADATAEALEAAASPSPSQTTTDALSGDPYGPRRWNSTLVPLSGKNRSLNEFSVERLADDAAAPKHTLVLLHGYGAGLAFFYRNFEALSRLPNWKLYALDLPGMGRSSRPPFRIAARERDAKIDETESWFVDALEEWRVQRGIDKFVLCGHSLGGYLSVAYALKYPGRLEKLVLASPVGIPEDPYAVREEMPESGESGMAENGFDHDDGLTVTDERGAVGSGTATPPRAGRAGADNNNFLNARSKAGGGGGGGDDDPNAPAPRKPLPKWLTYLWEANFVSPFSLVRWSGPLGPRLVSGWTTRRFAHLPPAEAQALHDYSYALFRQRGSGEYALPYILAPGAFARNPLIRRIDAVGRGYIDGPAAASASASASASASASAGSLQRFERETGVPVVLMYGDHDWMDVAGGYAAADLLNERRRRALEEARSDEERGRERGGGKVVIIREAGHHVYLDGADQFNEVMLEEMRETEKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX69</accession>
    <name>A0A6A6NX69_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_55367</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="12"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX69"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051403">
        <property type="term" value="P:stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07856">
        <property type="entry name" value="STKc_Sty1_Hog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000049">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000050">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038783">
        <property type="entry name" value="MAPK_Sty1/HOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="361" mass="41223" checksum="7CF3535DD5361DA3" modified="2020-06-17" version="1">MAEFIRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSAKDQLTGQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENVIALSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAACIFAEMLEGKPLFPGKDHVHQFSIITELLGTPPDEVIQTICSENTLRFVQSLPKRERQPLSTKFKNADPQAIDMLEKMLVFDPRKRIRAAEGLAHPYLAPYHDPTDEPVAEEKFDWSFNDADLPVDTWKIMMYSEILDYHNVDANAAEDAVAQADGVTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX74</accession>
    <name>A0A6A6NX74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_386618</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX74"/>
    <dbReference type="OrthoDB" id="549750at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051196">
        <property type="entry name" value="RSAD2/Viperin_antiviral"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21339">
        <property type="entry name" value="RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21339:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT NUCLEOTIDE DEHYDRATASE RSAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="239" mass="26770" checksum="5CD94E036763AC2F" modified="2020-06-17" version="1">MLPLEEVQRGLRMLRAAGMRKANFAGGEPSLYKPYLGALTRYCKEELGLDSVTIITNGSLIDVEWMQEYAAYVDVVVVSCDSFDEETNVAIGRGSGGNVAQLAEIARLCDEFGVKFQLNTVVCALNWCEDMAAKVAALAPFRWKAFLVLVVKDEKDGESPATLRDVGKFHISNMQFNIFCDRHKHLDCFVPESNEAMARTHLLLDESMRILDKRKGRITRSESLLDVGVEKAMRQAVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX79</accession>
    <name>A0A6A6NX79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_287901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX79"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046452">
        <property type="term" value="P:dihydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="7"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="223" mass="24495" checksum="1BA418628C05F43F" modified="2020-06-17" version="1">MPSSPKPLTLIVAATATRRAIGRAGTLPWGRLPDEMAYFASVTRRVSHPALRAPHTSAAPGAPRRPRNAVVMGRRTWESIPARFRPLAGRVNVVLSRSGRDAVRTLENVAAAAAEEEETDETAQATTLPPVARIFVIGGSAVYEAALRHPRVRSVLLTKVHREYEDADTFFPVDLDRDAGWTKRDTRALEAFADQEGLGGMKRNGDVEFEFCLYEKCELDNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX99</accession>
    <name>A0A6A6NX99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX99"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="10201" checksum="8F9B95319E22483D" modified="2020-06-17" version="1">MPSSCVAKLLLRTELWASAYLYIAQLLSDPATNYPMQPPAWILIPHIQVMAGKGESTHARYGRGGDASAPRRIPDSVYIGFATLYSSLCDVRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXH5</accession>
    <name>A0A6A6NXH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">beta-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_364684</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXH5"/>
    <dbReference type="OrthoDB" id="434at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000757">
        <property type="entry name" value="Beta-glucosidase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF28">
        <property type="entry name" value="BETA-GLUCOSIDASE L-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025656541" description="beta-glucosidase" evidence="15">
        <location>
            <begin position="19"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="16">
        <location>
            <begin position="655"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2456505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="736" mass="78175" checksum="8CF47EBED2B3DA99" modified="2020-06-17" version="1">MLGSRIISLAASAAVAFAQTYSGGFDGDWDAAYSQAESDVSRLSLSDKIGIVTGVGWSQGPCVGNTHAANSIGFPSLCLQDGPLGVRYATGITAFPAGVQAASTWDKKLIYDRGHAIGEEAKALGIHVMLGPVAGGIGKFAAGGRNWEGFSPDPYLTGIAMIESIAGMQDAGVQATGKHYIGNEQENRRDTISSNIDDKTMHELYLWPFADSVWANVAAMMCSYNKLDDTWTCEDEHAMDELLKEELGFKGYIMTDWNAQHSTVESANAGLDMTMPGTDFNGDSIYWGNQLQSAVQQGQVSEDRVDDMVTRIIASWYLTGQDQSYPPVAFDSWNGNGGPDVSGNHDEVALAVARDGIVLLKNEDNILPLSNPGSIAIIGSDAIANPQGINSCADMGCNQGTLTMGWGSGTVNMQYLIAPNDAITERAQQSGGSATTSGNDDANQGRSAAQGADLAIVFINADSGEGYIEVEGNFGDRNDLYAWHNGDDLVRAVAEANDNTIVVIHSTGAILMEDWIDMAGVKAVVWAGLPGQESGNSLVEVLWGDVAPSGKMPYTLAKTAEDYGTSIVTAGPDNFEEGVFIDYRHFDESNIEPRFEFGFGLSYTTFNYSEISVEGAPSAGPATGPTVPGGAADLYETVSTVSLTVTNSGDVAGAEVPQLYVGYPSSASGQPPRQLRGFDKVMIEPGESADVTFEIRRKDLSYWDTDAKQWVVPEGTFTLDVGSSSRDLRSSGEITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXI8</accession>
    <name>A0A6A6NXI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pleckstrin homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_59348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXI8"/>
    <dbReference type="OrthoDB" id="5579281at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902657">
        <property type="term" value="P:protein localization to prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040345">
        <property type="entry name" value="Mug56/Spo71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039486">
        <property type="entry name" value="Mug56/Spo71_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057379">
        <property type="entry name" value="PH_SPO71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029217">
        <property type="entry name" value="Spo7_2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28076:SF1">
        <property type="entry name" value="PROSPORE MEMBRANE ADAPTER PROTEIN SPO71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28076">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15404">
        <property type="entry name" value="PH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23207">
        <property type="entry name" value="PH_SPO71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15407">
        <property type="entry name" value="Spo7_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01316">
        <property type="entry name" value="Spo7_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="678"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="771"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1155" mass="130720" checksum="61A6E2505D0152F1" modified="2020-06-17" version="1">MTTQGCSQSRQTPSNPALGPDTYTAQRLATPEHLYMTSRRCFIGPIPEGWLRSHRRDWYKHHLHINYSSRAATFSANPNVSRRRRITGLEGPSVSAAFSHSFPQPDDLLEEVEEEEEEEEGNGTAGGDAASRGEGGAQAVLDNPPAMAVPRASQPTEEVGESENRAQRHAPPDVDGVVEGSRPIEGWESEPEQGEPAAASRSQAKRPLQGHSSRGPSSRSFYTASEGSPKQDAPGPPAATKHPAGREDLAPETQQANGSAPSAETPTASFTESNAGGRQVMGSSQALGATDSTASLLRKQTSRADDEGQGASGDAPQRSQLAEAAPERYVGLDGAEDEPRREMPGASGLHALKRKVGDGAVHFNIPVDRRDGAEHAKMRMKQTNLRRASRTWRRNKARDGQIVKTEKMLVRVEQTQQQLTDDYDENDSQKTETRTIEKWREYLVVCRESADENAEFVVQMYTSRVIPEIEETHKKRRSKHTIALNRKSTKVNLYSSLDKTFVICHPYKKGTRIYIMQPRTAVNSVEWYTFLRNSLGWHRAAELHIYVPDLNVRIRLQDPFEQLETSQDLDRAAEGDDEAILRAMQEEQRIAKNIVGRCVDVLRKSPEWDEEVLDAWTRGKRIGLAWRRYDRLEWIHGANERKMYGTIALMKSHELELRPKEHYPTIVMDDKKERIEEPVPVEGFLVRLTSQKGTERRLGKLFYKRLYFSTHDQYLVYSKPAKATPPPPPKLPASENARIPVARQIAEKIPIIYAVNPYPVEGGEVTWLSSGGSGRAVAPEDQEHHDRDAYDEAERKASLILDSDGYVDLRNVVQVRKMRKGATPADEHVDSGSDVDFDESVRDTNREDGTTKQPDNERTFEIVLKNGLVIRLQAFDKMTRKEWMKRLRALVQYWTSRKSSDIQLFKSVRQRNLEELNIDEETEAHVGQFARKWEVTNTYASPELYNMCGISCCRAIRVSSVLLRVRFRTNTIQMSGTLYHKPRRHSTFTRCGVLLCHGRLLLFHDKLRRRSGSEVANIQNDRFSTLDLRDCYLYSGLLTENDLLYTNRTFDSNRPGHHALPRIYLEDGWTSTDEDVMTCFVVWHGRRRSIFRDTSGGESKRGKLKLVSSLGVPGRSIVFKTRSRAERDHWVLAIGMEIERLEQNEDVRFTGASSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXP0</accession>
    <name>A0A6A6NXP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_348269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXP0"/>
    <dbReference type="OrthoDB" id="5518345at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.80:FF:000005">
        <property type="entry name" value="Proteinase inhibitor I2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="2">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="7633" checksum="A693E5A502C3346D" modified="2020-06-17" version="1">MPSINVTLKEGASPDQLDAAKKAVADQGGKVVHEYKLIKGFTAEFPPDAVHTMKTNEHITVEADQEVRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXS5</accession>
    <name>A0A6A6NXS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_262460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXS5"/>
    <dbReference type="OrthoDB" id="4074350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="8"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="427" mass="45370" checksum="80CD47625FCA9234" modified="2020-06-17" version="1" fragment="single">DGSDGPWSTFAFRVGTPPQTVKLLIATSGQETWVVNSGACASAGSEEETALCDRDRGFTFNVTNSESWSDNGDYVLEEESNLGYGGIGNYGFDVVTVGWEGSGGPKLDDQIVAAIMAEEWTASGMFGVSPRPTNFTDFRNPRPSFLSSLRERNLVPSLSYGYTAGSRARAGAGVLGSLTLGGYDASRRTINDVTFQLSSVTYRDVVVGLRSVRAPGALSALSSSIYAFLDAGTPHIWLPEDACEIIASAYGLTYDEESDLYLWNETARDAMDVTSASGNLEFELAPDVQSGPSVTITVPFTSLDMVATSAYPGLGTANTSRYFPMRRAANATQFTLGRAFFQDSFLIVDYERGNFSVAQARFDSQASPDLVTIKALGSDGPDTAQVDADDSRSSSSSLSTPAKAGVIAGGVLLLLVLLILALGAYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXW9</accession>
    <name>A0A6A6NXW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_347008</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXW9"/>
    <dbReference type="OrthoDB" id="204711at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000021">
        <property type="entry name" value="SFC1p Mitochondrial succinate-fumarate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="116"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="217"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="34803" checksum="CD11B879B6F588AC" modified="2020-06-17" version="1">MSAKSVSGPGGKTPTSAATNLIAGGGAGMMEALACHPLDTIKVRMQLSRRARQPGAKGRGFLMTGAHIVKRETPLGLYKGLGAVLTGIIPKMAIRFTSYEWYKQLMAGKDGSVSGQGTFLAGLAAGVTEAVLVVTPMEVVKIRLQAQHHSMADPLDIPKYRNAAHAMYTVLREEGFGALYRGVSLTALRQGTNQAVNFTAYTEFRAFLQNYQSTTDLPPYQTMAIGLVSGAMGPLSNAPIDTIKTRLQKTPAEPGQTALQRILLIGRDMWRQEGFRSFYKGITPRIMRVAPGQAVTFTVYEYLKGVLERGREMLPGGKYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY57</accession>
    <name>A0A6A6NY57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 6A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_347312</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY57"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="507" mass="57332" checksum="FB130EE50682B321" modified="2020-06-17" version="1">MLIRTAVYDGVLLTNALFVLALSAVAVFLYNYLLRPAFPAGAPKVIRENYPVLGAIDFFRKRRELFDSGKSQTSTGNFSFYVGKLNVIGLTSEQGRQVFFENRALSFSEGYAVLFGQNAKPPKLEFSEGESKFSQHFGKRLIQLVKRENIYRNLPNLISDVRAKLQPFADANSGIMEPFDIIYKIVFQLTMRTVGCNDFADDPVLLEKTLALFEYIDKSATSTGILFPWLPTPARIKRDFAGARLYMMFRKVAEERKKLGKRDNDALQFLLDEGDTIGQIMVFVVGALFAGLLNTGINAAAICMYLATNSEWMAKARGEVESVAARHRKDANAPLAETLAALPDSAWEEEFPVVEMCLRESIRLQTRGTAFRRNNTGRDIPVGKEIIPNGAFVTYHIDEVHMNPNIYPEPDYWDPSRYLPERAEDQKVHWAYLGWGVGRHPCLGMRFAQLEVRIVTAFFLAMFDFELVDENGNLTSRLPKIDRNGTSAGKPDEPVFLKYKVRDQMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYF2</accession>
    <name>A0A6A6NYF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_346007</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYF2"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="94"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="294" mass="32341" checksum="A83B058248AACDEB" modified="2020-06-17" version="1">MASRGYDVVVDVDTEGDLGHTDLQEDLEFHSSNFENPQGRGKIPPDQSGSFLGGTSSSRGPASSKHFLWNLSFYAQFFDVDTNEVIRRCGAAVFPRANFLDVLEGNPDLYGPFWIATTVVIILFLTGTISQYLAHQGKEHFAYNFKLLSGAAGLIYGYTGLIPVGLWGTLKWFGSESANLVECWALYGYSNLIWIPVALISWSRISALNYVFVAVGFAVSALFLFRNLYPVLSATDVRTSKILLIVVVALHAGLAIAIKILFFAHGSPAAKESPDDDDTDDEDRIKFARMLFGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ05</accession>
    <name>A0A6A6NZ05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_372411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ05"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025682443" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="398" mass="43952" checksum="8EAD073E94E66CB3" modified="2020-06-17" version="1">MRYLSVFLATTAGVSALATPRAPSNIEQLIARQKASTYGADRLAGRALENLVEYANREGTIHKRQAECTPETADVRKEWSELTDAEKKEYIAAVQCISTAPSIGTDVFSGARTRYDDFVGTHIAQSLTIHGTANFLSWHRYYTWLYEQALKNECGYTGAQPYWNWGMWAEDPLNSPIFDGSDTSMSGDGAYREHPSLNMAGKMYNPANGGDCITEGPFVNFTVNLGPGQKLYDFVADNPGADHLGYNPRCIIRDINKEVSMDSTQDHHTTDLIENYNDIVSFQDRMQAVQPGFFGVHGGGHYTHGGDPGGDFYTSPGDPVFYLHHAMIDRVWTTWQNLDPDQRTYAVGGSVGAMFGGFDQQQQEGTLDDPLDLMVVGDTITIRDASSTLGGSFCYIYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ14</accession>
    <name>A0A6A6NZ14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_379866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ14"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025499354" evidence="1">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="20296" checksum="618316597F140F12" modified="2020-06-17" version="1">MKAVAQLASVALFASAALASPIERREAMFKLRLSSTAYPPLDGKYLSSAGAAGAEEQPTTVGVFGDSSADASYTVQLVPGDAAGTYELYQAPNDGVHQLGLYGPMGFSSLAELEDPEDKVYIPEIEVKYSRWNITEAEGKTLLRYADEVESRWAAQPAADDNWEVKWYDGRNPILANTMPVEVEVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ58</accession>
    <name>A0A6A6NZ58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">BDY21DRAFT_344705</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ58"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02086">
        <property type="entry name" value="P-type_ATPase_Na_ENA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000016">
        <property type="entry name" value="Calcium-transporting P-type ATPase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000020">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000039">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000047">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="880"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="922"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="973"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="1006"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="25"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1057"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="1058"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAF2457031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1082" mass="118667" checksum="00873C6CB536B1D7" modified="2020-06-17" version="1">MAKDKKGPSLEGHVSGQSNEPMSKPAHSLSSQAVIEETKANADDGLTTAEAKSRLEKFGRNDLGDAPGVQPVKILLRQVANAMTLVLVMAMAVSFGIKSWIEAGVIAAVIALNITVGFFQEFQAEKTMDSLRSLSSPTAMAVRDGDTVSVPTAEIVPGDMVEMKTGDTIPADVRLVEAVNFETDEALLTGESLPVRKETEETYPEDTGPGDRLNVAYSSSTVTKGRARGIVFATGMYTEIGTIASALRQKQSKRRPVKRKEDGRAGPHRYAQAYALTGFDAVGRFLGVNVGTPLQKKLSRLAILLFGIAVVCAIIVLGANEFSGAQEVVIYAVATGLSMIPASLIVVLTITMAAGTKRMVERHVIVRNLKSLEALGAVTDICSDKTGTLTQGKMVAKKAWIPCLGTYSVGTSNEPFNPTLGDMSFMEKQPRDIDFVQLDEKEGVVDAHELMKHNDEHLLAYMNVASLANLANVHKNPEGEWHARGDPTEIAIQVFASRFDWNRLKLSGGEKPAWHQVAEFPFDSDVKKMSVIFRENETNTNWVFTKGAVERVIYSCTSVAWNKGEGYIPMTDKFRNEVLANMESLAKLGLRVLGLASKTYTDEIDEKNAGEMDRSLIENDLVFRGLVGLYDPPRPESAPSVRQCHEAGIKVHMLTGDHPGTARAIALEVGILPSRMNEVPKDVAESMVMTASQFDKLSDDQIDALPTLPLVVARCAPNTKVRMIEALHRRKAFCAMTGDGVNDSPSLKRADVGIAMGQAGSDVAKDASDIVLTDDNFASILNAVEEGRRMFDNIQKFILHLLAENIAQACTLLIGLAFKDSRGLSVFPLAPVEILWVIMITSGMPDMGLGFEIAAPDILTRPPQNLERGVFTLEVMVDMLVYGLWVAALCLGAFTLVLYGFGDGDLGINCNDVYTDACDTVFRARATCFACLTWFALFLAWEMVNMRRSFFRMQPKSKKYFTQWMYDVWRNKFLFWAIIAGFVTIFPTLYIPVINHIVFKHEGISWEWGVVFVAATLFFAGVEFWKFCKRVFFRRRARKSLGSLPADDIEARVFGNYFSGSPQGESSPSTQSEAGNEKATGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ88</accession>
    <name>A0A6A6NZ88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_53908</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ88"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="198"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="454"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="509" mass="56051" checksum="2C689542B830E7C5" modified="2020-06-17" version="1">MPTLTGFLKKKRTKDSAGSKDLDSPSSPVTPTISHGSATNKDSAQPTPVTPTAPKVTDFAQHQPPPQQQQPAGSKPIDTPQQQQLQAQQLDNFAPSPGTVPAKAASDETNAAGGGSSSAAAQPDAQMTSPPPQSNIPSIQNLINPPSGEQQEQRQQQQHQAGAAAGKDASNGSAIVPSTQTPVASTRQTKGKYTLEDFQLQRTLGTGSFGRVHLVQSKHNNRFYAIKVLKKAQVVKMKQVEHTNDERRMLQKVKHPFLITLWGTFQDSKNLYMVMDFVEGGELFSLLRKSQRFPNPVAKFYAAEVTLALDYLHSMNIIYRDLKPENLLLDRHGHLKITDFGFAKEVPDITWTLCGTPDYLAPEVVASKGYNKSVDWWSLGILIFEMLCGFTPFWDGGSPMKIYENILKGRVKYPPYIHPDAQDLLSKLITHDLTKRLGNLHGGSKDVMQHPWFAEVTWERLAKKDIDAPYVPPVRAGVGDASQFDKYPEETEAYGAAGDDPHGKLFADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ95</accession>
    <name>A0A6A6NZ95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inorganic phosphate transporter-like protein pho88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_344615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2456999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ95"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="20938" checksum="5E67A97CEDBCF920" modified="2020-06-17" version="1">MAISPQVTNVIIILFVMQVAKKIPFDDPVVLNAVRGLYVTSNVIIAGIYLYIQAQINKKKDRTTIQYVEPAPMGSEEGPKNVTTTVMAYDSQQLRGMFKTQLMGVGMMAIMHLWFKYTNPLVIQSILPLKTAVESNLFKIHILGQPATGDLKRPFKGASGLLSGLQGGDVKTDKKSIKEAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZS4</accession>
    <name>A0A6A6NZS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Spindle pole body formation-associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_372042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZS4"/>
    <dbReference type="OrthoDB" id="5383703at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021589">
        <property type="entry name" value="Cut12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11500">
        <property type="entry name" value="Cut12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle pole body-associated protein cut12" evidence="3">
        <location>
            <begin position="215"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="553"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="626"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="787" mass="84444" checksum="9FC2F8825A2FF7B9" modified="2020-06-17" version="1">MLSWLTGPRITNVAEDLQAPDDLVGPEPSYVEPPDTPAPVFAVRAFKHAIWGTPPPPTHFDLSVEEKKRRSNESARSMKVDNREKLDKNKPSSDTTVPNIAKNKIENTQQSSQTTSQPTQRRSSDSAAVAQQPSGTSPTKQAPAGILMTPGTGATRRKTVKFGEHVVDNEGKRKSGIPSNVPGKFPSPWTPKVGSGASTNEDKGNSKTKGTAHSSSNKLNAALQDAARETATGNNAQDFAPPTKRRSEVDAIAVALSSPGAKPTKSRDDADLTIDVLEPRSESGRYWKAQLESYAERSEREIRKLIAKHQLAKEYAKKKDGEAVELRAKVEKLEAEKKRARGREKTTEEQVRDLRERLRAVMGENAGLVGEVSGLKRRVADLEGKSNCVESTGEARNAGATSSRDTGSSRPPSSVVAPMATTITPPSSTEQCQQSSSAPSSLSSRPRRSTTPEIEPPPRHSSTNSGAATTVPDPANKPTHNPTPNRFSTGAPSRSYARRSTLTGPSPRPRRMTSSPDMRRRGRREIVGDGDVALGPAPLALHKSQSMRSPLLRAREGRDGKENTRPEDAGQAREARDREKEKEKERDSNRLPGASMLARDTPDPWSFQTRQHPHQRSSSPFDQYPSSAGASARKSAASAATSAAAPGNRPPSRSSARSAQPLRGAASHQELQQRAAPPAPAPPHGFPHHHHHHPGHQHRRRQSISQAPAAASAGGGASSAVTDGAPMHMPAPAPPSGRGEGARSGVHARDFGLRGMPRSGDEAGMSAEAFARAQERIAMRRAAGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P061</accession>
    <name>A0A6A6P061_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_371982</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P061"/>
    <dbReference type="OrthoDB" id="2016913at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1008" mass="111462" checksum="21868B2DBFB8B1E1" modified="2020-06-17" version="1">MATLSRDELVHKIETLYSATNPAVIEAVQFELLGFQRSTLGWQLANKLLEDGNPNVRFFAALTFTIKVNNDMEPLSGDDIADIRGKLYSWFFRLVRAQDAPLVTRKLCSAIVIFFMNRRTEPENVVELLLSNLAAVNNADAKPIGEVIQKLPVQQCVPILWLATGMVEEAGKMDAHSALNENIRKLLELNRQTVFDLAMYTFSTQTDSTGGPLDEEFRNRLRATTFECFQAWALHDIGNPAIFTNYPLDKLRALLNQVIIWCGESNESEALEGLGELLNSCLKFFQPEHLSTISEMLRGPWGKQWVSAILSEDAEESSESFVRLVTAFGIAIMSQAISNPDNKETIEIMEIMFALISCPGYPVEEDTICVLGLEFWSTFVERLEDDLSDHVDVWKPYIARVIRQLLMKSTIPPKSETDGWSDDTRKEFQVFRREAREINISAFMLLGNDLLYSLVHEALEALKTKSWLSVEAALYFIDGLAMSDSLLGGESEDAAIENLIKSTLTPELVNGDGIPQRLRVTVATLLGNLTGFFERSASANPALFFSVLDFLFGMLPMDEKIQQSIARTIVKLCESCNKLITQWLDHFLEQYERLRRATEVSGSTKARILGATAAIIQGLDSDEKRFRPTSILLTMIEEDLQTAIGAPDPKLPAAIELAQHALSCLHHIAKALRSPDDAVIDLEAESSSEPFRKPASEDPWSPTHERVLNIINGAMVALGGPAAASDDAFEDVLGIFKCGYTERSGPFALPLQSSVAFFDFTWETIPSTQLAALLSTLSTLVSSQAGDAAFEPLALRCARLLAELMGAKVGQPANDPEIATCLLDALQCFLRRRRGRDFCRVILAYADARAALLNFALLCVCGQDILPKRSAAAFWATFIPRNKAAAATQPTGGMLSPDVHREVEETLYPALCEALACNFGGLAARSDLDALCKPLRQLLDNDTRATRQALKMALYSDGFGQRSGVSDEDKARFLTQVSSPETRRGGRLVSVVKDFWIKCRGSGLGYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0G3</accession>
    <name>A0A6A6P0G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_286333</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0G3"/>
    <dbReference type="OrthoDB" id="61815at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="177"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="583"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="686"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="595"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="688"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="710" mass="78794" checksum="E301298FC98FDB44" modified="2020-06-17" version="1">MVLPKSKNAVGLGNSLMNDRFGKGRGGDMRRGNYQNAIERTGADGEKYVTNNKKDAEWVKMRSVTEQAALDEFLSTAELANTDFTAEKLNSVKVIHPDQRNPYLLSAAEERETVKKFDANKSRLTVPRRPPWDENTTPQALDEREKQALLDWRRGLAQLQEGEDLLMTPFERNLEVWRQLWRVIERSDLVVQIVDARNPLLFRSEDLERYVKEVDPKKNNLLLVNKADMMTLDQRYAWAKYFDENNINFRFFSAELARERNEARDQYEEYSDPYMVRKEAEHVEMSRATEASDSEEEEEEDEDEDEDTDQEISGPANNPVEESSSEDEGSRTSEDQREQNRTEPKTSVEIERARILTTEDLESLFLENAPDLPPSSDPSQPARKTQIGLVGYPNVGKSSTINALIGAKKVSVSATPGKTKHFQTIHLSSQVILCDCPGLVLPNFATTKAELVCAGVLPIDQQREFTGPAGLVAQRIPQTFLEAAYGMRIRTRPLDEGGTGSPTAHEVLAALARARGFATTGQGAPDESRAARYLLKDYVAGKLPFVTPPPANPPVDAFAFNQDLYDIAHLPPKRRAALMLPPKRAPSKWAEGDAARPAAGRDGAASGDADVDADVVPLVNRLPVQGEKATALDRKFFGPGSGDAGHMSLPAHMHGSGRKELSGRKQRAMVALEKGLDPEEVRMAMGNGKKHFKGNKRRGKKKGAAGTGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0H8</accession>
    <name>A0A6A6P0H8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_26476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0H8"/>
    <dbReference type="OrthoDB" id="3738195at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="23668" checksum="33DDECEC0013463A" modified="2020-06-17" version="1">MRRQNHGVFSMNIALSISHDLATGRTFAMLLGTSEEQTWWILDQLSDLPMLASHPLFLPTMLSKYTLSHVAYRVRLLHDALKDFEMQSKRTRFMNVTLADCDPTEELKKHDELRKDVLQIIQLATAWEDMLRTCSSMTEGIRQANKRIKFGTARQRRKVVKEVGAILDERSQFTRDETQNLVSQLQFVKERTQAQMNAIHHIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0S4</accession>
    <name>A0A6A6P0S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_371589</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0S4"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="706"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1072" mass="120944" checksum="D603DDC8C1D318A8" modified="2020-06-17" version="1">MASAPKEGPANKLLEQVIRTPGRQPSPQPTHLSVPGSGTTTPRILHEKGSGYVAPKFEGKEQQMEMVMDQVEDKGFIPPEFVESETKWFYNELGIDDMYFSTETVEAYETTLVNCDGSDANQTPRIVNHIHSLYAAKVAAYARDDKQLEIRLDKEAEDHAVYIDTSKPGISSVEGPKYEQRIDEKYLNGSMGCNSYRVETFRSSSNLPGGQSQQLRCYFVYQCDFANPNPGEKETQVDKIGEKRFLQKATTNTKEIYGSVLQSAVARTGPVIEYFEIEGSREKRLVLAYKQGSAMGIFSALSDLYHYYGLTSSRKYQFSNGYTVMSLYLRPASQTNTANQRFPPIEASIHQIIKEISLLYCIPQNKFQAHFASGRLSLQETIYAHCVWVFVGHFLNRLGSEYATLLSVLDTSNSVHAELLSKLKRRLRTETFTSDYILEIIHQYPDLIHSLYLAFANTHYVQTRGEHDDFLPTLSYLRLQIDKVLSDEELSDMINKTVVNEHHGMVMTAFRIFNHSVLKTNFYTPTKVALSFRFDPVFLPPEEYAQPLYGMFLVISSEFRGFHLRFRDIARGGIRIVKSRSREAYAINARSLFDENYNLANTQQRKNKDIPEGGSKGVILLDFRHQDKSRIAFEKYIDSIMDLLLPPSSPGIKDPIVDLHGKQEILFMGPDENTADLVDWATEHARVRGAPWWKSFFTGKSPKLGGIPHDAYGMTTLSVREYVLGIYRKLNLDPSKVRKLQTGGPDGDLGSNEIILGNEQYTAVVDGAGVLVDPNGIDREELVRLAKKRVMISQFDTSKLSPDGYRVLVEENNVRLPSGEIVHNGMIFRNTFHLRGTVQFDLFVPCGGRPESIDLSTAAKLIDGGKCKIPYIVEGANLFITQDAKLRLEKAGCILYKDASANKGGVTSSSLEVLASLSFDDEGFIQNMCIRPDGTAPDFYNDYVKQVQQTIKTNAALEFEAIWREHQATDEPRSILSDKLSMAITKLDEELQETELWDNINLRKSVLSDALPSLLLEKIGLDTILERVPENYLRSIFGSYLASRFVYEHGISASQFAFFAFMNKRMKMAGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0W5</accession>
    <name>A0A6A6P0W5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Kinesin-like protein KIF22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_391263</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0W5"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000072">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.320">
        <property type="entry name" value="Photosystem II 12 kDa extrinsic protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="2"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="501"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="604"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="92"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="770" mass="83572" checksum="E079DEAB0F7F8A20" modified="2020-06-17" version="1">MSVRVVARIRPLLKLECAKDTIVEGSPAGAERPGSPTLVRIPNPKNESESFSFQFHGVYDQEATQQEIFEKEISPTVKHLFGGFDVTIFAYGVTGTGKTHTMRGGKSLADRGVIPRLLSAIYRRSRKIEKDSGGETSVEVAMSYYEIYNDRVYDLFEAPEKRTAAGLPIRDNGGKTVVVGLSERTCWTLKEFEQLYDQANVNRSTSATKVRHLVLDRLNAHSSRSHAIVCIKVTQTSPTQTRTSTVSAIDLAGSEDNRRTDNNKDRLVESASINKSLFVLAQCVEAISKKQSRIPYRESKMTRILSLGQNNGLTVMILNLAPVRAFHLDTLSSLNFANRTKKIEVNEVENEPVFRAANGPGGAKPGPAHVSGANIQRQPLRPLAAATNSNALPTIHENARKADKPVKQFSVYSDTRKPGRGSTVSAAGGAGAAARFQPGGNKRSLANGSGPFARPAKAIRPNADTAARGIRSAATAMAAAEPALSKDQLEALIERLVEEKLASKSAPSSSDAKRSTADAGAAAHQQLQIPPDLQRRLEALEHRVDETEDRSRKEGLQYLLLARQHAARGEDGAALRMYGLARPFFPGNEKLAGKMRALEERIGGGDEDETLAPAPVSRKLARAKKTCDDDDDQDGDYEDAADDDYEDDDGFRFKHKSAPRKRTAAKASSKPKVAVFRDEYDAEDADGAAVALLQAPRTPRTQHLLRVINSRDVAAIRNLRGVGAKKAEAIVNALCEAHHEEELITDLAQLGGLKGVGSKTVENMRAGILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1J4</accession>
    <name>A0A6A6P1J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CwfJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_344574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1J4"/>
    <dbReference type="OrthoDB" id="444325at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061632">
        <property type="term" value="F:RNA lariat debranching enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07380">
        <property type="entry name" value="MPP_CWF19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF4">
        <property type="entry name" value="CWF19-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="3">
        <location>
            <begin position="322"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="2">
        <location>
            <begin position="531"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="587" mass="64009" checksum="978F83E7F97B989C" modified="2020-06-17" version="1">MSSKIVVVGDVKGQFSTVFEKISALHAKNNFTLALIGGDLFADPSSPTADDTSNVSALIEGHISVPLPTYFALGRHPFPAAAVDRLNKSDDGELCENLYFLGKCTTIKTAEGVRIVALGGVLDQDGDSGGKYSPFYTEDDCRTLGRGGAGPVTAGANGAEILITCDWPAGIRSGSRATYSSDSSPLEQTCVANVCAAVKPRYHFSTSAAFWEREPYFHIPSAEDDDASKLYPITRFISLAPFGNANKQKWIYAFTVDPSAPAPLVVPQGVTISPLSISTKKRAALPTQNEQYRFTAGAESHHLGHRHNKRQKKRHDKQPPPGPSECFFCLSNPNLATHLLASIGSEAYLAAAKGPLPMNTTYTSLAPSFDFPAHVLIIPLSHVPTLSALPNAESRNAVQEEMLHYRWALQQMLVEKGCGKLGAVAWEVSRERGIHAHWQWMPVEAGMVTKGLVEAAFKVEAENEGWNSSWERHAGPGKTADEKSQGDFFRLWIWSPPQTPGNMAGGGTPNNDAEYGENLDEDITSLTLPLNSSFRFDLQFGRRVMAKLLGLETRLDWRACAQSQDEEATDVEAFKKAFEAFDFTLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1W9</accession>
    <name>A0A6A6P1W9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_21247</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1W9"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000664">
        <property type="entry name" value="Protein arginine methyltransferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="5">
        <location>
            <begin position="76"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="29144" checksum="7C2F79B9EE465E85" modified="2020-06-17" version="1">MSSIIDKAREIVAINGMASKITLLQGKMEEVELPMPKVDIIISEWMGYFLLYESMLDTVLYARDTYLKPGGLIFPDKATIFMAGIEDGEYKEEKIGFWDNVWGFNYTPLKTTAMTEPLVDTVDMKAVVTDPTAILTLDLYTVKPADLSFTLPFILTVRRNDFVHALIAWFDIEFSACHKPIRFSTGPHTKYTHWKQTVFYLQDVLTVEAGEQIEGMLENKPNTKNRRDLDIKIAYRLVTDDPNRQAEGSGEYKMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P228</accession>
    <name>A0A6A6P228_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone transcription regulator 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_343050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HIR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77564at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1784"/>
            <end position="1855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1903"/>
            <end position="2111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1784"/>
            <end position="1814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1815"/>
            <end position="1827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1832"/>
            <end position="1855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1961"/>
            <end position="1972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1986"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2004"/>
            <end position="2019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2032"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2071"/>
            <end position="2081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2097"/>
            <end position="2111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2111" mass="234032" checksum="F814292CFEA406B3" modified="2020-06-17" version="1">MSAFHAINIESDNDSDSEVDDTKEIQIEEALKLYQTALKLHAEGPASYPKAAEAYNALFESEIFKYPESQSEYRRAELYESTAVDYDFLPVDDVQSGAVGGGTAAGIGGESAPNTLPQILHLSYKNHGQFMLDQLQHRLQEHMSKLRQHENKTAPSTAITPSHLSVAADGPLRSFAEALDKDDSDLDLWGRASVVASVAGSKRIARYCLEAVLDGDDESIESILRLPGLEEGFAAYQLRELAQQLRDDLSMMQAPLSGLQRKQLSKAIKKRLDPYPALPKPPSHVDLKADPKTLGNVPTKVVLNSTSRDWTAVGEVIRQQVIGEQSGYKDEGPGVGVEIQAPLAGEEEDTEEIREEVEGVVIAAPSEGKPDSESGQTNPKDTQAEADDKTSPKDTNGSAPPMESQSSVTSRKRSTESAGLPETAEGGRARSKRIRARESIAEGGSSAADAAALELARQIEDQMQGYIQADAWLFEVTEKLFSRLHIPIPRSPQTLRDSLAAEDVDEDSSASAERDEWRAAVRDLDSILRNCPPEAAGILLSAGDQTLDQLGGTSKEASLNAVLAHAKAATSPPDAKVNFPESKGLGRWLKWVNEQWMASSEVAWEWVACLLRRGAFPGLKNTSSYLYHHWSEDLKRIVVQITVRMDEYIYQQLVSQIAAVDKKALKENASGKPFNPAPDDEATIDMVQTLFELHLDVYSLIKHPGSGVDAETQTLQRERLERWARLAREAVNLHHSGHQLVTIDHLGLRHIWASVFHINVCESVSQAHVLQCMAELRHVFEAVGKPTILVQNNAIMPELSVDAVDRELSRIRTKDFFTRVFEHDEHDPVAVINSIEPILEPPPLPDIEEHNADGEDGVMEVDGADHVDPGYKEVIANESEETALIRNKVSPLYEMTKFLQSANVTLRLSLWQRLREAYDAIGYPPKIVSCYLRSIETLVKEFKSQSYRILPQQQRRLSLLRWLKIIDEMLLRVLDMAKSEHDAFDMIDASHLKSSIGALASLSILLHTFNVYEDMARVGQGGAGMLASQANPSYGVAAGKFKDIQIRLWMLQYLLLKDAISQNHERFESPDEDRLEYLRAVHNAAGMRSFCHASNKAFLKMMKNDLLQNGDYINSDLVIELSQVLYDLYGLKCFENPADCEEHNVPQDPPTVKTATKLIDFVMAQARKVPMKDLPKTELKNTIEKLHGTIGKRALPPEDIFVNRRVLTAFSKSPINPVNLFRCLRGAPPGISTKRIPITNPSPLSAPAAKGWFFLMGMIALTRFRSQKRVTQGPTEDINYAVTFFTQDLEFGENRWETWFRLAQAHDAQINEAVTWSAEKINAAPSTPLAMELQLMQRAAINCYSMAIGWATRGDADVTGAEIRAKLVDLYAGFGMRVYASTRQPFDMAPFKFREEEMRFFSGDEIYKQQSFNELTEYMAWKFAASLFRRAVAIGVDVAHAGCNGEGVRVAKSKWRNHYMLGKCLWKMYTADEGLRRPPNATPPTVQDVLEAFTKAIETLPSQKSGKDPILEPHYKIVSVVHKMVQRRGLTPQDGSEAIKATPYSKKVTPSTNMETWNNYILQVLQALRNADKSAWHHRITVRAAHVIYDANPDKIAAARGVKHELTQQIFTKTMVMQVWRPENERPGRHFVYTTRYLRFFLRILVQLEDRMNLEQLAKRVRRKTNDFYEHAKVWQELCTAYLKLLRRVAKVPESQEEAVFKSIPNEEFQIQAPRLQTWIHARMLQEPDPEDADLRLQELVSVLRDAAELRKTNNNLMKNTLIDDLIADTYACIYAQVTPGLEAQSPQEQQQQTSDSASQQQQKQMQPQQTEQQPRPTNMMSLNNLITVDGTPASTSQSHQQQPHPTTFIQQPTPTQPMVFNSQDGLLSVVAPSKPRTKGVGRRELLRRAEAAALPAQAGMVPGTGVPIRGPSTSGVKAEQSGAGASGTGGSARGQQTGAKDGCRGSSPGPGNAVGASLKENQRADDVKENEGSATKNAGQEGAGVEVKSAPVSAAVSTVVSVADEDESELSELNDEDVERPAPGELGAIKEEDEEGEEGGEEGEEEGEGEGEEGEDEGENGGEGKGDADGGGEEGGDEMEIESRYVTPETSMRGVDGSDDKDKMEVDEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P244</accession>
    <name>A0A6A6P244_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">26S proteasome regulatory subunit 8 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_385652</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P244"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000068">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="165"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="389" mass="43669" checksum="0C558F681B9AD5D2" modified="2020-06-17" version="1">MECDYFYRNKIESMKLEIIQGEAMLRRLEAQRNDYNSRVRLLREELGLLQQPGSYVGEVVKVMGTKKVLVKVHPEGKYVVDVSESVDISKLTVGKRVTLLSDSYKLEKMLPSSVDPLVSLMMVEKVPDSTYDMIGGLDQQIKEIKEVIELGLKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCKFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRVEGSSGGDSEVQRTMLELLNQLDGFEPTKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPTVEARADILRIHSRSMNLTRGINLTKIAEKMNGCSGAELKGVCTEAGMYALRERRVHVTQEDFDLATAKVLNKHDDKQMSLTKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2A3</accession>
    <name>A0A6A6P2A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2A3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="75" mass="8377" checksum="CF557BA82F8095C0" modified="2020-06-17" version="1">MYQSWRVIVRFSVISPFAVLAARLRHMLSSRPNPPGRTAFSSGSVSLVVFRTSPVNRKALEGVCQLVYSSKFQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2A9</accession>
    <name>A0A6A6P2A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_285308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2A9"/>
    <dbReference type="OrthoDB" id="5572108at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000232">
        <property type="entry name" value="Actin-related protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="533"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="537"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="602"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="759" mass="84508" checksum="A8F2819740875623" modified="2020-06-17" version="1">MVGKKSGKALQREEGLERTDNNMDLTTWPQVNMINQKNYYTEYLKRDDQFLAFRTQNEEATNRMVREARDRDRALAQSSRGVTMAGDGTAGAGGDAMDVDEDLVAEDNTAAVATQEARGSKIIVMHPGSQNLRVGLASDALPKTVPMVIARRDKENESEAGDGEPSPKRVKIDDELPEEPEKWFGEEFSKKFASMATELKQRMRNNKRRLLPNSKELVINYNRRGAVETISEHNDPLRIDWTELPPNPAKAPDYFTGQAALRIPEQSKPRYKLFWPIRNGWFNEHDYTNKNLLFEDFSTIVEEALKSELGLSRRKDWSQYSCVFVIPDLYEKNYVISILDIMLRNFGFGKVCFMQESLAATFGAGYSISCIVDIGAQKTSICCVEEGLCSENSRINLKYGGWDVTETFIKMMLHDWFPYEDINLKRRYDYLLAEELKQKYVTMNESDINVQTYDFHLRAAGQDTRKFVFKTYDETMLAPMGFFRPDIFDNSWKLERRRNLIDRSYDLYDGSPNDPTSIAQNFALEFYGGIPTATNGSADGPSSSTPAPSSLAPPSRQQPASFLSRFNDLESTPRTSVANSPAPDGGPGTSTPQPGRASPAVGGAGGLGDGSGGPAAGPTAAMPVYDPTAEKIGAAEARDRVLPSMPLDRAILASVAQGARGDERKMRDFYGGIMVVGGGSKIPGLNNFLEQRLRELQPGLAKEILVGVPPRDLDPQVLVWKGASVFGKMSSSGNDSWIGQKEYDVLGSRLLMHKCMFNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2D5</accession>
    <name>A0A6A6P2D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Paf1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_414894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2D5"/>
    <dbReference type="OrthoDB" id="10260285at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="490" mass="52939" checksum="4A30402B8E6568BD" modified="2020-06-17" version="1">MSGSSRPVYHQDYIARIRYSNALPPPPNPPKLLDIPNTGLASGQYTSAGYASRLAREQPLNIEADAELGMHVDLVGLPGVFEGDERSIQLLDNPPPPHPGDRPLLRPLAALGKPAAQTANVSFLRRTEYMTGGAVSTLRYDNSSASRDLFRTVTSRTAGAGAARKKRRGADPVNQNDPGYIVRAIAKGFDLAYPRDAGKLVGADGEPVKALETALEEREAWRRPQHPSRPDLKLLDAYPVLPDLGAFPDTGSYLMVKFQTNPVAVDADRYDDRLDVALLYPVESAANAEKLAVARAAYEARPEAGKPPPVPTYDYQLYLPSSSSVAGIKRKFGRAGDEGEDDNDGGGGGGGGGEGAEDALYDYANPATGARSFRYDRVRRYETFHQSGEAAEPYAENVALALHDGAGEDGAGARQKAAYYYPIAQRTYIRSFRKDKVASMLGGARAPDLEEDRETVDTLEVRIADPDEDMRAHVAEHLAKFDPLGAEVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2D9</accession>
    <name>A0A6A6P2D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_371070</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="3"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2D9"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25585">
        <property type="entry name" value="zf-CCCH_DUS3L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="264"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="528"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="202"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2458190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="693" mass="76778" checksum="B05D9B240E8E900B" modified="2020-06-17" version="1">MDDKPTEPPVSTDDAVEAAGYDEKPGTAGGRSGGRNTKPNKKKERGQNTNRTFGSSRDVLQLCSTRTFAPESAPEECKFGSKCKFEHDLRRYLREGKRADLDTLGGTCPVWAVRGACNAGWKCRFVGSHSREMDEGGLVLVEDEERKKRFVEEGDGKVGDMGVLNVVSLEDKMRLSRKKFKAEKSDKYLEYLAEMYQLERDAKADEGDEDGEEDEDDKKKDNTKTKDADGQDQAKHDNRAQYVEPPFLPSEKRRLYYGPDMPILAPLTTQGNLPFRRLCVSLGAQATWSEMAMGLPLLQGEKSEWALMKAHASEAVPPTLSPSLLSTESASTSASNGSMKNGTILRFPTGYDNAKDTKFGAQIAANKPWIALKTTEVLTTLCPSLRAVDLNVGCPLDAVTRLGAGAALLDTRGKLEKMLRGMSAVSGEVPVTVKIRMGPREAAPVAHRLVTRFALGGPEARARGEAGAGVAAITLHGRSKMQRYTRTADWGYIADCAALIRRIHVERAATADTAREPDERDLPNGGRVFFVGNGDVFSHADYGEHLRESGVDAVMVARGALIKPWVFEEIATGQYLDKSASERLGYVEQFAKWGLEHWGADEMGVGQTRRFLLEWLNFHHRYVPVGLLERLPPRINERPPLYRGRNEMETLLASDNYKDWIKISEMFLGPAHPNFRFEPKHKSNSYDTLEAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2U4</accession>
    <name>A0A6A6P2U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_363394</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2U4"/>
    <dbReference type="OrthoDB" id="5546837at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460:SF1">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="208" mass="22148" checksum="45E381A325611E6C" modified="2020-06-17" version="1">MDFAPYQDASPERNRALSPPPPTSPRTSPRPSVNPPRSANIGTAAMASPAPHSGGGGGGGNPYFGGDGSGWAGGGGGGDGGRGGSIGGFGGPREDVDVFETRLGIRMDYEACLAYLLLPPAGGVLLLVLEHRSDYVRFHAWQSSLLFTFMFIVHVIFSWSSVISWLLFVIDLVLIAWLVYRAYRDADTLDRCEVPFFGPLASSILDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Z1</accession>
    <name>A0A6A6P2Z1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Z1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="9123" checksum="3F63D1E05A03BAB0" modified="2020-06-17" version="1">MSTADRYSNADSDIYLGRFSSCAQIRATSIGSGYRNPSSERKSARLHYHTKYTLALYPVQSRMFCERDKVCRTLYDQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3C2</accession>
    <name>A0A6A6P3C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative voltage-gated K channel beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_204397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3C2"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF6">
        <property type="entry name" value="VIC POTASSIUM ION CHANNEL, BETA SUBUNIT (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="346" mass="38555" checksum="628DDFE611F559F1" modified="2020-06-17" version="1">MSVPKDLPKMQYRFLGRSGLQVSAISLGGWLTYGGHVEKENTFACMKAAYDAGINFFDCAEGYQSGDSERLMGEAIRHFGWKRNDLVVSTKIYWGQAFGDNPVNNGGLSRKHLVEGINASLERLGLDYVDLIYAHRPDRHTPMEETVRTFNHIIARGKAFYWGTSEWRADEIERAWAVASRLGMMGPLMEQPQYNMLARARVEAEYELLYPERGLGLTVFSPLKGGVLTGKYNEGVPEQSRVARSEDRFVQGLRKQVGGDEWAGNIATVKKLQPIADKLSTNMAALALAWVLKNPNVSSAITGASRPEQIFQSVKALDLLPKLTDEVMAEIEEVLGNKPPALVKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3E1</accession>
    <name>A0A6A6P3E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_284127</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3E1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07106">
        <property type="entry name" value="ALDH_AldA-AAD23400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="LUC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="52298" checksum="8557129F04E78305" modified="2020-06-17" version="1">MSPSKVAPFCFDTFYNVVDGKTRTAKTAHRGINPMTLEELWPVPVATQQDVDDAVAAGMRAFPAWRDTPIEKRKELLGKFAELFSAYADDFLSLLCQETGKPRPFAAMETNGVQKLIQAHQDFELPVEKIEDDEKVITTTYTPLGVVGAICPWNFPITLSMGKVVPALLTGNVVIVKPSPFTPYTALKYIELAQQIFPRGVVQALGGDDRLGPMFTAHPDIAKISFTGSIATGKKVMEASAKTLKRVTLELGGNDACIVFPDVDVAKVAPEVAMGAFFNSGQVCVATKRIYIHEKIYKDFVAAMVEFAKKLKVGASDEEGVMLGPVQNAMQYERVKGFFADSKEKNHTFAHGEPDVAGSKGYFIQPTIIDNPPHDSRIIQEEPFGPIVPTQPWSDLDEIIQRANNTKAGLGASVWAKDVAQAEACAKRLEAGNVFVNSYVKPNPKAFFSGHKESGIGGEYGTKGLLSYCNAHVMHSYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3G0</accession>
    <name>A0A6A6P3G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_267618</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. Interacts (via N-terminus) with TIA1 (via C-terminus); thereby promoting spliceosomal U1 snRNP recruitment to 5' splice sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3G0"/>
    <dbReference type="OrthoDB" id="76567at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000059">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037969">
        <property type="entry name" value="U1_snRNP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="115" mass="12278" checksum="A7224DD487AF3559" modified="2020-06-17" version="1" fragment="single">SPLTLLALFCDYCDVYLTHDSMSVRKAHNNGRNHLRNVVEYYQQIGHEKAQSVIDSITSSYNAEGQSAPNPMFAPPPGAGSGLPPGMPPPPHSGPPGSHHHHHHPPGAPPGFPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3L2</accession>
    <name>A0A6A6P3L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_370778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3L2"/>
    <dbReference type="OrthoDB" id="21418at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029196">
        <property type="entry name" value="HAPSTR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38645">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38645:SF1">
        <property type="entry name" value="YALI0F12243P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15251">
        <property type="entry name" value="TAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="30451" checksum="D8E553D7C08729A7" modified="2020-06-17" version="1">MESMRSLNTSLPSASPRKQPPPEQLLQAFKTAALSVTNLYKTAASDQTRAHAEGYQDALDELLGFLDKEDMGLGEGEGWRVRQWIMERQQTEGRAQQTMADSDGDEEAEEERRARSSSPATASKPDALVNRQATPQRDQPTQRPAPDETARSESAPPNTHSVVHRQTPPPPVPRGEFTFRQPPPTPMSSLQDLDLDSLDFTPRHMRLEVVSRAHHRSPRHNRQAGAAGAGRNGSSLGTGAGIKRKFPLGDYFDIGGLGLGNGNGKDGHNGGGGGGKRSRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4U1</accession>
    <name>A0A6A6P4U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_283761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4U1"/>
    <dbReference type="OrthoDB" id="3738511at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="244" mass="27447" checksum="F7E419E1D549CEA6" modified="2020-06-17" version="1">MRTFERSNGLLPLRLPLKYNAEKNKTKETVQWVEASPWSFYKKVYRIELGGSVAVAHKKPNTKEQFTIKSVSASGDQIRLMHRLYHKNLLSLYEVFYFDDAFYTVSEHMAISLTHVIGCPEPLTEGQLASITKQCLCGISYLVSQGLSHTDITCPNILLSFDGVVKIGRAIMSVMNKRLKLDGNLSISNPGLWSTEAVEFLSMTLDAAPGELSTHSFLEHARGEDLPWFVIYTLRTARVIVATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5E3</accession>
    <name>A0A6A6P5E3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_282766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5E3"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="23913" checksum="1894A7AA78C8A596" modified="2020-06-17" version="1">MVIQDDPSLPVLSASGLRRIGIGTSGAVFALDEERAVKFAPVSYNDWTTDFHFKDLLIERSVYERLGSHPRICRYIGPVRRGIILERLGDAVRKRLMELRGQGRRVPYEQALKWSRQIAEGIAYVHRKGVIQGDIGCHNALLDGDDIKLCDFAGSSVDGKPPLAGYELRSQRWEENDQGISDALITSEIFALGSTIYEIWTTNRPYHDKPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5G9</accession>
    <name>A0A6A6P5G9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_410000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5G9"/>
    <dbReference type="OrthoDB" id="4152802at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="806"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1149"/>
            <end position="1159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1179" mass="128438" checksum="FCD28F04DAEF6196" modified="2020-06-17" version="1">MAGDVAEGTDAAQPYDARRGAAMERIRKGAPVWDGFELPMRVLGHFEEASQAPERQHARAHRERKYSLCAMRDAATGTSLPRKRSHGLRLDCPGPGTPGRRARATDAGVAFAASPPPRLHLPAAGRREKGHGAPGRALALQPTLRRGLAGGLHIHNAYLHPAQTPLADARQKRSPSAARGLRPPSTRSVVFLYGPPALASRLAWARSASLAPPPPPTPAADTAEPPPPGPRRPRRATRSRLGRARQPRPAPKSLHAPARPAPAPRTKPRPRGPRQLVPPIMAVWPFGRKRRRSRIKADGSEPVAPASTPPDGQQQQQQQQPPPPQTVDAADRSRASATAERDRNRDRAVSRRQSRKKQRRASEGKTNPRQPQPQQQPATPTDPPQHPAAGRRNGDARPSGEHITALPLSEPLSVSPHLRPVTDEHVNSPYDFNLQSGSHTSLPTARERGKLQRPPNLRKRGSANDSAHPRRKASKKRKDDHVREEEIRAMSAPVATYRRPTSLGGEILRRDSKKGRGPLNRHFERPTSNISLPVEESIHSSMSGSSEPRAFIVNAFDLFNPRPTIRCSYTAHVVSTGYTAPGSDHSRSESRKEKRPTLTNQELKASKTIDALADDMDAGDLRELLERDQRRREKRRKADEERIRRRLTRRAEKQKREEAKAAGKENEDPQGAQSVGLGIEATSSTTPHRDDASLKKDSAIMQTPSKEIPPAIQRRSDEGGDPSPMEFATPVETPAETPAVEFAQPVAISQSRTSPPVSPSPRPHHQRGPSNLSHVASLRKESAPQVEPPPPVEQGERRSSAPESGSTTTSRRSAWTSFFRRGGTKRGSADRGRATPSSEVSFSNTSRESMARQPPPAHLHHVHQPASQLRARSGTPVRTQSKFREDLPELPLSPPDSRVQSPEATVPSSGVLASRRGYRTPASINVEVGPGAGANRTRPDSPVSPGARRSGLMSQSLASVDSEGSWLSGKPVKRSSMHPYARTSVGSGSLQKQREEEFAASYEELGMSDEEYFRRQASGHDNRRSNRASSNALAPTSDDEDDAPAFNARPKDNDEEAIVRGDVGRQPTVVHRENRVKSREGLLNDFNALEEGSAPTSPTVSPTDDCASQHSDIIPTTEQPTVQRAQSIDLGKGHARHLSAGSARLLDIPSKRTSLDTKRASNSSQTPTPGPAPTVSEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5J5</accession>
    <name>A0A6A6P5J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_199822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5J5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025622695" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10890" checksum="7FA28E1EBC65BA92" modified="2020-06-17" version="1">MAAFFVLLEAACGLAHFVPLLVSSHGSFRRMSRHCSWVKAIEACLMRTAGVSEQRIVFPVRRSDGVLNLRFVSGKSALRKRRCSCSKDVFTERCLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5N2</accession>
    <name>A0A6A6P5N2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_188476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5N2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21864" checksum="5BED2DD716F31B4A" modified="2020-06-17" version="1">MLRRRRARTRGEQATGRPSTRFRRAIQRVTSNRLYVGRVWPGRLAEQGIHGWPRRARLGWVGRWSRGGLGRRRGTSYIRARTRAQPKPCVSELATAQQDSWRPSLLTVRRCLFLWALLSCRPLASLFLFLLCSSLVGGGFIVFLPGYVGSFFCSLLCRDIYAFAAEARPDCWQRARNEKAARVQLIAATAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6I6</accession>
    <name>A0A6A6P6I6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_338301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6I6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="120" mass="13289" checksum="F232B404DE9264A8" modified="2020-06-17" version="1">MGLPTPLCPRPSATTHPPKRDLPGYRLRPPARSPTRPCHSLTHPPRTTATPPSLFTFPGESTQARTQKVDFLPFPRRQFVDIRLLQSRLACLHSAVATRGAKNASAAYRVFQGHENRANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6K2</accession>
    <name>A0A6A6P6K2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Sulfite reductase [NADPH] subunit beta</fullName>
            <ecNumber evidence="6">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDY21DRAFT_301011</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the reduction of sulfite to sulfide, one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19">Alpha(2)-beta(2). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="6"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000007">
        <property type="entry name" value="Pyruvate:ferredoxin (Flavodoxin) oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000003">
        <property type="entry name" value="Sulfite reductase [NADPH] hemoprotein beta-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000004">
        <property type="entry name" value="Sulfite reductase [NADPH] hemoprotein beta-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000085">
        <property type="entry name" value="Sulfite reductase [NADPH] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000051">
        <property type="entry name" value="Sulfite reductase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000016">
        <property type="entry name" value="Sulfite reductase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01540">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011786">
        <property type="entry name" value="CysI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010029">
        <property type="entry name" value="PRK13504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493:SF47">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="22">
        <location>
            <begin position="789"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="192"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00057613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00063391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00067595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF2459073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1529" mass="168402" checksum="C079370F4575CA95" modified="2020-06-17" version="1">MASIITAGEAAARISYLSSDVVVSVQPSLAADSEFSKHLRTFAQKKVPSVVAKTAPEVLPVRENVDPLLSALGPARNGKAVSVTSPSHVLVQSVPHLYQLAQCPVVMHVSLQPSRYPDYSDITSIRQSGFVMLQSESLQEVQDMALAAHALARRSGKGVIHFFSSANMEADDPIPLEQLDLVRQLLDVGVAPASGDSTAPDGGLYAEDGRTPSTTLPHNQNSATGVTHPTEIGNGAAQKGPEAGSVTASSAESSRRESSDDSGRVSSLATSVESIETRPITSDGIYNLVSQIWDAIRTSTGRSYDAFTYSGPADAENALFIFGSDPVMFAQAIDRANSSDLYAKAGILTTRLYRPWLGSKAAATLPRTVKRISVLEQIRRKTTKWGPLLLDLLMSFKTAAGTTPVIIGYKLGYIEPATIQQALRGIFQNLLSEAPIQNLEIGRPDGPTTRAPEPPLMRPELENAYLKILDQLFGDRLYIANQLQSSHAGISSRLSASPEYGFGSLIARSQRRQDFISKVQAAIKSHPFTTDAPRNWLSKWALQADDSKKANCLAPEVVSRLSVDGSPLANELLSARSMLLKESQWLIGSNSWAYDLGNSGVHHVIASGANVNMLIIESQPYSERAATDAVRRKKDIGLYAMNFGNAYVASVAVYSSYTQVLSAMIEADKFNGPSVVVAYLPYSREDDSPLTALQETKKAVDIGYWPLYRWDPNGGEHGEPNFKLDSERIRRELEEFLKRDNYMTQVMKRHPDLASNLSGSYGSEVRALQKRKAKDAYNELLEGLYGAPMTILFASDNGNAEGLAKRLGNRGKARGLKTMVMAMDDYPIEDLSTEENVIMITSTAGQGEFPQNGRAFWEAVKNSTDLELSGVNFSVFGLGDSHYWPRKEDKIYYNKPGKDLYARILALGGKSLVECGLGDDQDPDAFQTGYAEWEPKLWKVLGVDKVADLPEEPPPLTNEDIKAASNYLRGTIAEGLRDETTGAISASDQQLTKFHGTYMQDDRDLRDERKAQGLEPAYAFMIRCRLPGGVATPSQWIQMDDISTNLGNETMKLTTRQTFQFHGVVKGKLRPAMQAINRALMTTIAACGDVNRNVMCSSLPQHSKSHADVWAVAKKISDHLLPSTTAYHEIWLTDENDKKTQVAGDAVVDHEPLYGPTYLPRKFKISMAIPPYNDTDVYAHDIGLIAIKASDGRLDGFNILVGGGMGVTHNNKKTYPRTGSMMGFVPAGKAHIVCEKIMLVQRDHGDRKNRKHARLKYTVDDMGLDVFRSKVEDLWGEKFESPRLFHFDSNIDTFGWQRDEEGLNHFTMFIENGRVEDTASFPMKTGLREIAKVHKGEFRLTANQHLILSNVSDGDLPIIKELLAKYKLDNTNFSGLRLSSSACVAFPTCGLAMAESERYLPELITKLEEVVEESGLRQDSIVMRMTGCPNGCARPWLAEVAFVGKAYGAYNMYLGGGYHGQRLNKLYRSSIKEEEILSIMKPLLKQYALERNEGERFGDFCIRIGMIKPTTEGKTFHEDTAEVESDEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6U3</accession>
    <name>A0A6A6P6U3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_338664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6U3"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="330" mass="37453" checksum="9B694E0398B1A15F" modified="2020-06-17" version="1">MATSEPEVPNPVIEPDTSDTDSAVGSDIHSELISLTSSITDFVYKNGRRYSAYRGAKYVLPNDERESDRNDLLHHIYGIMLDGRLIIAPIGNHLKRILDIGTGTGIWAINVADEYPNAEVIGTDISPIQPSWSPPNLQFEIDNVELDWTYSKIFDLIHFQNLNACISNWPKLLKQCYDNLAPGGYLEAKETDGVTVSDDNSIPENCHLRRWEKECRGACDKLGLDTSIPWRLKDMFKDAGFVDIREQTWKMPFNAWPKDPQLKQLGRYQLVQYLDALQAYALGLLVEVQGWTKEEMEVFLVGLRSDLKNTKFHGYNVFRVVTGRKPKATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P769</accession>
    <name>A0A6A6P769_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P769"/>
    <dbReference type="OrthoDB" id="2384430at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF11">
        <property type="entry name" value="PROTEIN DSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="764"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="807" mass="86040" checksum="510E7AB484E146B1" modified="2020-06-17" version="1">MTGNRPNFINLRANSEGPPASSSSSLLSSGDLPSPRTGEVPPALSPLDAFAFQGRLLARRFEQPSRDGRRLSRLPATTVASEFEKARPSYLRSASAGSGAETPPSARDDGTSTRLPFAADEPDHVDPARPKSVYPLIQSDDGPFGGSQPSVPFQPELSRVEEGLTPPSTQPEEPRHQVNDYFAIPRAHSPEQIDSRVEQSAAGDQTPHPPAGVQRTITIDSVASSAYSQHSSLAPPRTSPSLNRSPRASPTVRSVPGDSSDDVDGLSLGGSLYSLPQRQLSTTNTSVSRSHSPYSPQSHSVPDAPPRSPSVCSEYSVGGTTRLPRPPHFNFSRPLSRASRPSFDAPSLEAPSRQASGDSGSGLRPSFDLPGGAPSRQDSADSPVTPFPNDFAHTPISMNSEEYFNDSDASVGTGNMPAPSYIYSKYSLPRGRILQRESISAAEFLGPHFQQWDVAPSRKMPMRSAPTSGARPPSPPSPPRPRTTRTDTGMPAAGTALGTPPLGVDTLRPKTTDAAPHPGFTRSHSHAPPRSPREASGHKPTGSSPSMHSSSNATIKPSSASISSSIPPPVPTSLDPDMTPEDHLDRGIERHEAGALQESTYHFRLAAKAGLPTAMLLYALACRHGWGMRRDMAEGVLWLRRAVDCAGGELADDEEGRNKAATGANVLEHRTHRAQFALGVYELGVSYMNGWGIQQDKALAVRCFEIAGGWGDADALAEAGFCYTEGIGVKKDLKKAARLYRAAEAKGMSMAGNSWIYKDKYMDDADSTRSGRSGRSGKKAAEKKSRDKSRTRTIFGRKKAAAASASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L5</accession>
    <name>A0A6A6P7L5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_336700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7L5"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF7708" evidence="2">
        <location>
            <begin position="109"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="358"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="61378" checksum="BF7FEB6A805062DF" modified="2020-06-17" version="1">MRTMGPPGQPPSRRSTQEALDKLAKPRERITQNTAWYTAGVDFCFYAPAQEACNRSIERLRKLNLDDEELDLLANPPSPEDFVAKLKVLEAHQEDRARRSTLMKRTSEFVNVFCEFANRCKGIILLLTPQSPEYSVTFGMMLIVFNAVVTKKEREESLLEFVQTLSSELPIVDFYKTVFPTNAMKATVARIYVEIMKLLDEAVAYYRGGRLSMIVDAVMQPKSKFDVYIANIETEIKNMNHLKDAASVAQAADMMEVVQGTGLVVARIYENFESTSSAIGTSIEILNRKLDSLTANTNKMLHFEMLKHTRSLQEALLADTPAYRPADEELSVVLGRNLQLSQKDRWENNGVLDELILWSRNARDKLFWIGGDIGNQDAWVTDLSRDIVQALQPQLLTLLFAFCDQPANEPLTPILVVKSLFAQLLDLHPGLAYQNPEVCNLWRVRRAVTFSQVWRIFEDLALRVANLFVVVDRVEQCEADEQADVSHQLFPALVGLVQKSQVAGSEASVIVTSIYEPPELPEELEAWLYSVDIDTTKRPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7M7</accession>
    <name>A0A6A6P7M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_361730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7M7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="130" mass="14063" checksum="74D7AD12E79A3440" modified="2020-06-17" version="1">MTEPAALLARPRCASAGLHFGNSTGRAFCRRIWRRVHPCWTVAAARSSGLNLETSKRATARNRAGPAMRSALAPCLFSTLARPNLTSLDFPEPLVGRRTTYSASQVVVIDHWSALLRRDVRAFGGALCGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7P5</accession>
    <name>A0A6A6P7P5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Yos1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_369885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the YOS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7P5"/>
    <dbReference type="OrthoDB" id="15356at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013880">
        <property type="entry name" value="Yos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858:SF0">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08571">
        <property type="entry name" value="Yos1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025463147" evidence="9">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="85" mass="9505" checksum="E756CE80AA56E0D7" modified="2020-06-17" version="1">MFLFGLTSLLKVCILLTNAIAILSEDRFLARIGWSSNVDPGFGNAQDTASIKARTVHLITSVRTLMRFPLMFINTFIIIYELILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Z1</accession>
    <name>A0A6A6P7Z1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_369947</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Z1"/>
    <dbReference type="OrthoDB" id="246406at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14856">
        <property type="entry name" value="TRAPPC4_synbindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.70:FF:000007">
        <property type="entry name" value="Putative sybindin-like family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF15">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18571" checksum="EE2DF130689C5EBA" modified="2020-06-17" version="1">MYDFPLPCPYSRVVFALLVINKAGGLIYNREFHPGLTKLSSNDLLILAGTFHGVHAITRNINPAGAPQVPGGNNPNLPPNPMSYQPTGIEVLESSNFRLQCFQTVTGTKFLLLTEPQQPNVDTTMRRIYELYSDFVMKNPFYTVEMPIRCEKFDRSLDGFVKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P812</accession>
    <name>A0A6A6P812_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_181482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P812"/>
    <dbReference type="OrthoDB" id="5135333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="165"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="270" mass="29683" checksum="B0539C77DC0F7DD6" modified="2020-06-17" version="1">MACNACSTVGQLLLSNQRFDHGVRLSTYGVMRLRSDCRTCQTIASVGVTSSSKGSIEDDTVIVLRLLALPAGAYQICDEENMGTFMIEVAPLIANDSSQSTGVLIDEQWIDMGRVKSWLAYCDRRHPWKCHGLPGTQRIVLGLDSILLIDVRNGNLVSAPATTRYFALSYVWGRGEGALEMRKGNYDALKRHGSIRPDHPKVPRTVGDAMRFVSAIQECFLWVDRLCIVQDDLEQKAKQIEAMGSIYANAYCTIIAGEGADAGHGLRPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P815</accession>
    <name>A0A6A6P815_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P815"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="274" mass="30469" checksum="0A6E014F8F69E033" modified="2020-06-17" version="1">MPPCGELKRVNCLQVPSPAPWALPTGCSSCRLSFLAAAARLHARLSRTTVWMARMGWDGWKDGEKRSANERANETQESVELGPRDRRPWGPGLFVAAATKCDDPVGAASLRWGRRSWRREIFWAYVLATRAHHMHTYTGSARSLPHPAVRPGRRRALRRRSAGWLAPWKVVFERENNARGLSVGLEAALKVQSEEEQAARRGGKAVQKARWTGETARLAPARASSRLPLRPRSGGATYLHDGSTTTGGLRSGPWQQLIDRPFRRSRGRACRPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P891</accession>
    <name>A0A6A6P891_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-hydroxyacyl-CoA lyase</fullName>
            <ecNumber evidence="9">4.1.2.63</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_408426</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 2-hydroxy-3-methyl fatty acyl-CoA = a 2-methyl-branched fatty aldehyde + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:25375"/>
            <dbReference type="ChEBI" id="CHEBI:49188"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:58783"/>
            <dbReference type="EC" id="4.1.2.63"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25376"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an (R)-2-hydroxy-long-chain-fatty acyl-CoA = a long-chain fatty aldehyde + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:67444"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:170012"/>
            <dbReference type="EC" id="4.1.2.63"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:67445"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.63" evidence="9"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P891"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106359">
        <property type="term" value="F:2-hydroxyacyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001561">
        <property type="term" value="P:fatty acid alpha-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02004">
        <property type="entry name" value="TPP_BZL_OCoD_HPCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045025">
        <property type="entry name" value="HACL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710">
        <property type="entry name" value="2-HYDROXYACYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710:SF2">
        <property type="entry name" value="2-HYDROXYACYL-COA LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="14">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="12">
        <location>
            <begin position="228"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="13">
        <location>
            <begin position="443"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="641"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2460165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="656" mass="67221" checksum="DC56247043206932" modified="2020-06-17" version="1">MSSSSSSPPATLNGAHIIARALRDLGVTVVFGIVGIPVVDVAEQMMNLGIRFIAFRNEQAASYAAGAYGYLTGKPGVLLVFPSAAAPPPAGLRGRAGSPVAEQASPASFAVLTDPTRRQIGNSSANAFPLLALAGASETHLATKGAFQELDAVSLLTPHTKLALRPASLALVPRSIATAYRHAWYGRPGPSFVDLPADLIQAAAPAAAVDFGARVAPPPRPAGDPARVAAVAALLRGASAPLIVVGKGAAAAGPAAAAAVRRLVESTRVPFLPTPMGKGVLPDGHALDAGAARGAALARADAVLVLGARLNWLLHFGEPPRWSPGARFAQVDLAPEELGRSAAAADAGLAVQGDVGLVAAQLLEQLRGWRYGGGGGAPGEEAAPPYLAALAAAKERNARRAAAKAADAGLPLSFERAFAVVRAALDRVAGPPERARVVYVSEGANAMDIARSAFRVGAPRHRLDAGTLAAMGVGLGYAVAAHAAYNGEVEAAPDPGPGRPARQRKKIVAIEGDSAFGFSAMEVETLARAAMDVLVFVMNNSGVYRGEAETAAGWARRRAAWLAGAGPARGGLRSTGLGFETRYDGLAEALGAKGYLARTPDELERATVEGFAAEGPVVVNVIIRSGAERELEFGWQGKSKKKEEGEEKEEKGGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P917</accession>
    <name>A0A6A6P917_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_335211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P917"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16902" checksum="CBABB90300B3A196" modified="2020-06-17" version="1">MARPRAAYRLRYWLHAKLASCKGCAHIVRAAAMPHERTKGISCIRVGGMCLTPNSLIGCSPSPDLVQMWWTLVRRRMGGPGRLCLVTPTKHGGFSHCHGGGFTRALTADPARSYDIVPLGRACLRRKWSLSSYRELLTGRPLGWGRFIPSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9C1</accession>
    <name>A0A6A6P9C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">BDY21DRAFT_280750</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="19">Forms DNA polymerase zeta with REV7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000007">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.342.10:FF:000018">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000024">
        <property type="entry name" value="DNA polymerase zeta catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13 20" id="KW-0408">Iron</keyword>
    <keyword evidence="14 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="26">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="62"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="783"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="1043"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="1549"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="397"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="749"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="567"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="766"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAF2460555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1666" mass="189416" checksum="91A25ACBBEAF671E" modified="2020-06-17" version="1">MELFRFRLNCVDYYQTSPTDFDPDICHSSAQSQHHRDPIQVPIIRAFGATETGQKVCAHIHGALPYLYLEYGGSLEDETVDSYVHSLRASIDHALALSYRYNPYDNPRRIAYVGHITLVKGVPFYGYHVGYKYFLKVYMLNPANMTRFVDLLHQGAIMKQTFQPYEAHIPYLLQWMCDFNLYGCDFVDCEKVMFRAPVPLFNELKNMAHKWHNQSIESEWISDPESYQRQSHCSIEIDVHVQDIANRRVVKQRLIHRDIIERFGQQGPEDKVVHSMAGLWKDETIRRKRRMGIENPSSTPFAEDAFVSMSSDPRRTGKGDWVHEEEYRNLVDELVRKEQENSNGPKPSFDDFVKRLDPENKIKTAFESIEDLFPANLARRGLDPDDDDGVEDAVVDESRISVPQNADGIFTENLPGEQRSDGETWPLGERQTMSSEGTSSDPHDVEEMMLASPRKRRKVSSESFSSIQRALVASGITKPVTLEERRVPFKDSTRMDDLLPDESNFGSSNLPSTQSSQTTIKAHANRDSKTVAFPVVKNANVPALSTSASQTSSQISSQKVEVAGYASSHQNTSTNTRSVASRSSGWGHSASKANLRQEITDQAWDLARNYRTAFPWGSQSSLYYAHLPPTAEHVGSTMLDHGLPQVIYQDAYYSDENDVPETSREYAGREFRFDSLSVPFLPDFDPTGLSPASYGEKPPAVVDEIRREVEHNERRQSCSLMVWEFANIPPSAEEVEQWLEEGRKTGRLKACQNDLSKPAKRDLPMQRSQIEEPTQQKSNGPQNVRRKTSVSLEAQYMSIMSLEVHVNTRDTFVPNPEHDEVACIFWCIKDDVPPETGYDRDELKVGVLALSDSSGIAQKISRQCNALVEYEEDELDLINRMIDIVREHDPDILTGYEVHNGSWGYLIERSRIKFEYNLAEELSRTKSKSHGRFGKNADRWGFQHTSTIRITGRHMINIWRAMQSELNLLQYTMENVVFHLLRKRIPHYSFPDLTKWYRSHNPRHLAKTVDYFLSRVQLNIRILDANEIISRTSEQARVIGVDFFSVISRGSQFKVESLMFRIAKPENFILVSPSRKQVGEQNALECLPLVMEPQSDFYNSPLLVLDFQSLYPSVMIAYNYCYSTFLGRVVSWRGRNKMGFTDYERQPGFLEMVKEHINIAPNGIMYVRPELRKSLLAKMLIDVLETRVMVKNGMKDDKEDKILQALLNNRQLALKLIANVTYGYASASFSGRMPCSEIADSIVQTGRETLEKAIALIHSDERWGAEVVYGDTDSLFVYLKGKTKDEAFNIGQEIANAVTKANPKPVKLKFEKVYLPSVLLAKKRYVGFKYESRDQTEPEFDAKGIETVRRDGTPAVQKIEEKALKILFRTADLSQVKEYFQRQCMKIMTGRISIQDFLFAREVRLGTYSDKGPPPPGALIAARRMLEDPRTEPQYGERVPYIVVSGAPGARLIDRCVAPETLLEDGNYELDTEYYISKNLIPPLERIFNLVGANVRQWYDEMPKVQRVRTTSAIARAQVPGDGAAAAAAINASGALRKTLENYMKSTSCLVCHGGLPAPTMVQQQDEPAPTLPVCESCASRPDLASLALRTRIHNSEARTLDISTVCRSCSGLAPEEEVRCDSRDCPVFYSRVREKARLRSFQSGMKPVIDALEKVELDVDDDLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9F7</accession>
    <name>A0A6A6P9F7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plectin/S10 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_335695</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9F7"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="18073" checksum="59981290BBA6CDDF" modified="2020-06-17" version="1">MLIPKADRKKIHEYLFREGVLTAKKDYNLPKHGDIDTRNLFVIKACQSLTSRGYLKTQFSWQWYYYTLTPEGLDYLREWLHLPAEIVPQTHIKQQRSHAPPRGMMGGDDRGPRGRGGPRGDRGDYRRRDAGEGKEGDAPGGFAPSFSRGGFGRGRGAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H2</accession>
    <name>A0A6A6P9H2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_335982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H2"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000001">
        <property type="entry name" value="Iron-binding protein IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="4">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00071673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="11627" checksum="28EB90BA24E8BA62" modified="2020-06-17" version="1">MTLTPTAVAQLRQLLDQPEPKLIRVGVKNRGCSGLAYHLEFVDKPGPFDEAVEQDGVKVLIDSKALFSIIGSEMDWVEEKLAKRFVFKNPNITEQCGCGESFSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9R2</accession>
    <name>A0A6A6P9R2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arsenite methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_406352</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O = dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:69464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:23808"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:183640"/>
            <dbReference type="EC" id="2.1.1.137"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:69432"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:27130"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:183640"/>
            <dbReference type="EC" id="2.1.1.137"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>arsenic triglutathione + [thioredoxin]-dithiol + S-adenosyl-L-methionine + 2 H2O = methylarsonous acid + [thioredoxin]-disulfide + 3 glutathione + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17826"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:183640"/>
            <dbReference type="EC" id="2.1.1.137"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.137" evidence="4"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9R2"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030791">
        <property type="term" value="F:arsenite methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008823">
        <property type="entry name" value="PRK11873.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="ARSENITE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675:SF8">
        <property type="entry name" value="ARSENITE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="9">
        <location>
            <begin position="67"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="30691" checksum="D6DF89718553627E" modified="2020-06-17" version="1">MSLKTKESTYETIRGVYGSKATAGESTETKSRIAAALGYDPEDAAAIPDQANLGVGCGNPLMIANLREGETVLDLGSGGGFDVLLASKKVGSTGKAIGVDMTEDMLELARRNAAKMNVTNVDFIRANITKIPVESESVDCVISNCVLNLVPQEDKPCTFAEMYRILKPGGRIAVSDFLALKPLPPKLKEDAKLWTECISGALEVGQMDQMLRSAGFQDLLLVDKHLGPSLYQDQTCCSTQEGSSEAGNSCCTSAAGSVDGPARAAESKMDSDLDQYLSAFNIYALKANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA10</accession>
    <name>A0A6A6PA10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA10"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="10022" checksum="8DF60C0C8A5A152C" modified="2020-06-17" version="1">MPHKPTDYSPPTRPNQPIPSPKQAPFAKPVPLSHLSQLSKPSRTAPNPVAPSYTSLGSLLPNNHQAPLANYLKPISSPPHPLPKPQTDSTKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAS6</accession>
    <name>A0A6A6PAS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_166870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAS6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16510" checksum="475571D785489A45" modified="2020-06-17" version="1">MTGDRPTPNGRTQRAMMFCFSAGAGFLVEGGARGEGLGEQSRCAPGRVRMASVAPQLGGFGRRRFVRRGKKVPIERCGEQNDRRKYGVGDAQLVSWTERRRELSEQPENRAIANGKSARRARETTARPPLVALLQLGMDGHDSRKRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAX9</accession>
    <name>A0A6A6PAX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_361117</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAX9"/>
    <dbReference type="OrthoDB" id="3638488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000192">
        <property type="entry name" value="Serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF76">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_135, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="300"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="606"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="680" mass="75847" checksum="100DEF576B20E0E7" modified="2020-06-17" version="1">MNQNNRLQLNFGFNDRNPNNYNAGGGPNGPGGGGGGAHGSDVGRAFPTTPSTFPQPMYPNQQGQQEVWGQQPSTGYANAGYFMNNPYQPQFQPLPQQQQQQQQQQQQQQGYRGPPPTTAAYDAATNGLVHQFSHQNLGGGGGGGGAGAGAGGSAAPRAQSPYGRQPSPSQRPRTAGAMPSAQQYGGYLNAPGMPQGGFGGGQMGGGAPSHTDDEPPAKNPDRYAENLQRRAKLSTELVSNFFKENVQRARDRNGRALELDGILKDPAIPEAKKEQKRNTMRRAEAQFLRFLRTKESPDNFQTVKIIGKGAFGEVKLVQRKNDGKIYALKSLVKSEMFKKDQLAHVRSERDILAESDSPWVVKLHTTFQDNTFLYMLMEFLPGGDLMTMLIKYEIFTEDITRFYMAEITLAIEAVHKLGFIHRDIKPDNILLDRGGHIKLTDFGLSTGFHKEHEASYYQQLLSGAKHKNRDNRSSMSLDQIQLTVSNRTQINTWRKSRRQLAYSTVGTPDYIAPEIFSGKGYDFGCDWWSLGTIMFECLIGWPPFCAEEPRDTYQKIVDWPRHLHFPPDQQLSRRSEDFIRSLVTDPERRLGRVGGAHEIKAHPFFEGVNWSQLRLIRAPFEPKLQSNVDTAYFPIDEIDQSDTSAALRAQSEARGEDLAAEMSLPFIGYTYKRFNAFHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB72</accession>
    <name>A0A6A6PB72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB72"/>
    <dbReference type="OrthoDB" id="3833686at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="89" mass="9731" checksum="1947A85DAEF16A75" modified="2020-06-17" version="1">MMDNELLISLATNLRNARNTFGEASPQYASLKRMIDEYVAGARAHAMQQQAAHSNNEAGAGSESERLSEHVGETLHHAFGDLAIRPKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBF6</accession>
    <name>A0A6A6PBF6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_331634</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBF6"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001834">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF152">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="37"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="273"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="499" mass="56736" checksum="F762838D52E4FF55" modified="2020-06-17" version="1">MRPSTSKHVRRQHVDIDFTLRRVFKKQAFRPVQREVITAALDGNDVYIQAATSFGKSLCFQLPAVVDHGITIVVSPLLALVDNQVSALRAANIKVATLNSQIPRPERDDILSDLRCGHPHTRLLYVTPEYCKLSHFRRHLEIVHAQRELARIAVDEAHCISEWGHDFRPAFLDLRWFKTTFPDVPIIALTATATSRVRRDIIDALGLNRHKLRVFEMTTLRPNIHYEVRFKSDDKGPYDDFLKWLRAAQGRRAARLAAAEERDGRRSALNDKDKSQDPGTLPGIIYTLYRKDCESLAAQLRSDGIGAIPYHAGLPKETKADHLAGWVAGRPGYAVVVATTAFGMGIDKEDVRFVVHWQIPKTFEGYYQEAGRAGRDGKAARCVLYYGREDRDRALTLMLRDALTKAAGRMQKAEPELAKMKNRSESFQELFMYCENTGACRHRLICDYFGEATPSMHCQFACDWCKDAKDLAERKEKGLVAENWCEDQMTPYGLLSWET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC14</accession>
    <name>A0A6A6PC14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_332439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC14"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025347780" evidence="3">
        <location>
            <begin position="20"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="121"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="282" mass="28693" checksum="3211929BABBB7CE1" modified="2020-06-17" version="1">MKTFSLLSALPLLGSLTAAAPVNKRDMVWVTETAEVVETVAVTVTVWVNPTDNVPEATATPGQFVEGAPQAEYSPDGGPAVPTTTLTSPSSSESAAPLSPPPSFTPEAAPAPESTTLEVIAPASSSAPAPASQAPEPETSEAPAYAPPSTSSEEAPVSLSTAEPNISSSSGSSSSGETFTGDITYYTPGLGSCGFTNSEGDDIVALAAGMMTSVSTGNSNNNPYCGKKITIEYEGNTHTAEIVDTCPGCDGASLDLTQSLFEKVAPNGDGRVHGVNWWFNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCR2</accession>
    <name>A0A6A6PCR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCR2"/>
    <dbReference type="OrthoDB" id="3553147at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF80">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="40843" checksum="756A07898E577BB4" modified="2020-06-17" version="1">MAWDELAVAAIIIQRIKMFEGFELAGTGGVSAIEEMRVQSRDNEEHGLLEYLRSTRHYRATDPRDRVYALLGVVHPEDAAAMRPDYSIDPKELYKRVALYLIEDRKSLDVLGYVGFRGTLHGLPSWIPDWSAVVPEEYMALADVSHGAYWLDQHKHPPVIDEIGYNSLVLEGKRIDAVMITGKEMGTSPIGHDNSEASLSVYKDWESLALSLDCYPANPDGDDVINAYWKTLIAGATENNEEVDADYGRHFINWYAKFGAGLLDTSGVPRIDSEVTNEEGVLIYGGCVFDATVGRRLALTNKGFLGLFPAGSKDGDVIVLLSGAKFPSVVRLLSDGHLLLGECYVHGAWPDELMDDKSLRRERFQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDR0</accession>
    <name>A0A6A6PDR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDR0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="35398" checksum="FBDE7BE28B368FF6" modified="2020-06-17" version="1">MPTNMNNLSMNTKAQVPADIPAEPFPGVDEEVPRKCFQDLKTAIKGLEVLCADETTVVHSDDEQRAQEAAGGAEMKDMLSSIVFESDDCDEDGDEDEGNEAEEDDEDNDDADKNENDTDADDASTASSESLNTALSTEDAIGVGIVFSDSDDTVDTIDTNPTTASPSSSSPLSSKADGLSDAGSDAGNADQAHAPEDDDDARADAVVAATLAYVRARARLENARVAAAARMGVLRALQVQRQRERERQQWKSWGRGPGSHCGRRGRVVGFCEGVKVGKQYEWRDYWVGVSWERIGELEREEEEEEGDERRKKVEELVERFRMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEE1</accession>
    <name>A0A6A6PEE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">5'-AMP-activated protein kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_330700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEE1"/>
    <dbReference type="OrthoDB" id="286637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025542879" evidence="5">
        <location>
            <begin position="23"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="82"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="157"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="226"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="299" mass="33921" checksum="597D367D8AB71DB2" modified="2020-06-17" version="1">MVRLLWWLADVLLYFGTYETTAIRSIVSAPLWDSKTSTFAGLLTTSDYINIIQYYWQNPDALAQIDQFRLDSLRDVEKAIGVQPIETVSIHPDKPLYDACRKMLESRARRIPLVDIDDETQRAMVVSVVTQYRILKFIAVNVKETQMLRKPLKELNVGTYEGVMTATMDTPVMDVIHMLVKKNISSVPILDVDGTLINVFEAVDVITLIKGGVYDDLNLNVGEALLKRSEDFAGIYTCTMNDRLDAVFDTIRRSRVHRLAIIDENARLKGVLTLSDILEYILLEGEGDSDVLSTRQEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEE6</accession>
    <name>A0A6A6PEE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial outer membrane translocase complex, subunit Tom22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_295738</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEE6"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2462137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="145" mass="15891" checksum="BB5BB56EA61C0CFC" modified="2020-06-17" version="1">MVKLEEVPDEELNATQPGPAQAEDEGDWESDSESDVSETSSLADETLYDRLAALQDIVPPTHRRRLTAAVSGTRSWLGWAARIGGKGLWVVSSSALLLGVPWALAYAEEQQMQEMEREMAMQKRENEVLAPGVQTAQQQGARPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEG5</accession>
    <name>A0A6A6PEG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_296134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM32 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEG5"/>
    <dbReference type="OrthoDB" id="10253744at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF7">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="325" mass="35816" checksum="3438B506829E4A7C" modified="2020-06-17" version="1">MSRLASLWRSPVRRVTFLRAFSRSLSDGVCFGSCPAPCSEYQSIPEGLDIDYKSPLAGTMAAYDRHVVIATGKKDWTSRIEDEENLAFVRALKRLISRGGKFHNPYHQIIVSASSFIPETSQEVNSSISAFVFPNFKYIPAISTDLVSAEEFAKDYLLPGSPINSGSSSDRYSLEMDVGRHVPSPNGAVLVDEVVILICSHGGRDMRCGILGPILAEAFQRNLVKSQFDLQSAKQQPSLAASHSRAKARVGMISHIGGHKFAGNVIIYVPRTWKWNPLAGWSIWYGRVCPEHVEGLIHSFRSGIIVKEHFRGALDGSGRIVKDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF63</accession>
    <name>A0A6A6PF63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_277256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF63"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015355">
        <property type="term" value="F:secondary active monocarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035879">
        <property type="term" value="P:plasma membrane lactate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000340">
        <property type="entry name" value="MFS transporter, SHS family, lactate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="52"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="504"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="58553" checksum="D3B6E576A5539DCF" modified="2020-06-17" version="1">MRNHMAAGWFYSPSQIGRYFLSRVPTLRPPRNTHATNPIKVLRKLDKHQWLMFAVGFCGWTWDAFDFFTVSLTITEIADDFGVENSAVSWGLTVTLMLRSVGALIFGSLADRYGRKWPFIFNLFLFILLEMGSGFCQNLSAFLGVRSLYGIAMGGLFGPAASTALEDLPYEARGILSGLFEQGYAMGYLLAAIFYRAFVPTTSHGWRSLFWFGAGPPVLIIIFRLMLPETNYFQVMKAEREAKHAAAHQSVQADGTIKTKKTNGLRAFAREAGRAIAQNWVLLIYMVVVMTGFNSCSHGSQDFYPTFLKDQIGMSPTQTTVITVVGQIGALIGGTVIGYVSSILGRRLTMLIAVVFGGALVPAYIIPRDNSLIAASFFEQFFVGGVWGPIPIHLIELSPPALRTLVVGLTYQLGNLASSASATIQGVIGERYPLPPAADGTERFDYGTVIGIFIGAVWAYLFFFLFFGPEMTPEEREERAAEAIEFENLRKQGVSMREIGISRAKGQQGSLGKEVIEQKEGPEQAEHVENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL32</accession>
    <name>A0A6A6NL32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_294818</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL32"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13934">
        <property type="entry name" value="RNase_H_Dikarya_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="8">
        <location>
            <begin position="67"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="25426" checksum="A7C3DF376364631A" modified="2020-06-17" version="1">MSHQSFQFFDSGSPLDGFGEELERQFDPQYSPMHQHVPENELVVYTPSKKVSQLQVMHPRTGALDLDKFTVVVFIDGACRGNGTPSARAAWGVYFGPQSPHNASDLLKADLPQTSTRAEIEALSQALRIIRDEISQDFSLQQIRIVSDSAFLVRAMSEWIEGWIENDGRNAEGRPVAHYETFKEIHERLDEMTYGDDGGLEFKFWHVPRERNEEADALANQALDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL93</accession>
    <name>A0A6A6NL93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_158389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL93"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="299" mass="32931" checksum="685D195854B2D7C6" modified="2020-06-17" version="1">MTSPNQLPFRNLSLDPNAPADMETRGMARARASARAARTQEGGRDSPNSISVDGINYDLSQLSARSRQRAIEGLNLETPYVQFFQIPPGSKPPYYAFRVSDREDFVIRMGPPGSSYEKPHCSLCSPKDRDACKVGGFARILAPSPIDARRRTRRGCPEQPLGRRLHGRLPQNFPAGRADSGGPDAHRRKPHLAGPGRGSGDADQQTRCRCRRRRRCDGHARRCASDGAGPAGPGAPGRRGREPPRSLPRPRPPRYPQVRSRQRQLYGGAAQRRAHAVPRRSVLRAAGSRAGRHLRIVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLF4</accession>
    <name>A0A6A6NLF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_261648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLF4"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="97" mass="10909" checksum="3C5EE9CB10076C07" modified="2020-06-17" version="1" fragment="single">LVGPACASDEAGSKWLAEFMHLVASDPPDYIGVHYYGTDADAAIKYLEAVHEKYPSKPLVVSEIASISRDKKEVYAFTAEVANWMDDRPWIFEYGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLH2</accession>
    <name>A0A6A6NLH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribophorin II C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_425205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLH2"/>
    <dbReference type="OrthoDB" id="432292at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044239621" description="Ribophorin II C-terminal domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="9">
        <location>
            <begin position="180"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="288" mass="29849" checksum="91299D0A4E79C048" modified="2020-06-17" version="1">MRLLSGLSSSLLLAGASIASALSWTFDEATVAVAARGSGVGGSTKEIFAPNKPLAKPLNLSAGDTLRISLTTLEGTKGKRPHQAFLTLTIPGTPLEESFALSVKESGKGKVEVTQKDLPQQLLTSTTPLEASITIASFGTTTPLSSPAFTLTITPDPMLPPPPASSGTRYAAQPLLSHTFRPPPSSPPFVVTLVFFLAVAATLPALFIAWAALGANLGHVAEAAKKAPVAHAVFFGSVVAMEAVFALYFVSWSLFRMLPVAAAVGAVAFVSGGRALSEVQERRLAGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLY0</accession>
    <name>A0A6A6NLY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_367579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLY0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025581830" description="Secreted protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="12109" checksum="444CB1559363882A" modified="2020-06-17" version="1">MALTFPLSATLLGTLITSVHLEALRSLPKFAASYLHAIHLGRSPFTRRQILRVTTQRKLLKRSARKLQNRSRKRIQTSETALRQPPSLQEVPGIFQPQRTLIWINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM28</accession>
    <name>A0A6A6NM28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative calcium/calmodulin dependent protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM28"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="313" mass="36145" checksum="1DB30192D79F5A8F" modified="2020-06-17" version="1">MLRTSLRMSSSPNELTGATSRRHLFKNSGMDEFVLKDIPKDIFSNFTEIIRPRLRESPYIRLPFDNIPGHRIFVYRYLIDDFLSLVRKHIPMRARKQILKASLLGIVELHERDIAHLDIKPDNIMANYSSVGNDIAIQQVQLIDLENAAYLPKGRCIKGMLAGNDNWRSPEAHFKGELNKPTGIFFFGAVCIYAVVGRVIFGPDEDFRKHEAQGALPVFIRFQRQVSYFGDKEGLHGLIKHVGDEEVNSQVLKMLWEERTEEHIPYEPFSRWPDISDTVFKDFVQKTMNLDPARRITARQALEHPWLANVEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMN4</accession>
    <name>A0A6A6NMN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMN4"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="126" mass="14865" checksum="BFCDFBDAFA40F8A1" modified="2020-06-17" version="1">MTGVSGGPFESEEQFNTWQLSHLLPNLPLSRRDLYQTMHKTYYKIVFAHGDLGFQNVLVKDGHITALIDWEDASWFPEHWDYCKTAGYLTGSDELYLALKKIFDKQYFEEYLMDLWFTREVQHGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMR4</accession>
    <name>A0A6A6NMR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_405292</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMR4"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="37846" checksum="70CF96D47B14986C" modified="2020-06-17" version="1">MSRSSHFERIDASFLVEEETANGCSPKHYYPANSDLDRHLHVWLCRDLRIHHKYVALKIYINRFKYHRELPIYEEINNLQTTHEGRNPKLIRQTLRYILTGLQFCTRKSESYTLPSNMLLGIHDDSVLAKFEQYETENPCPRKELDGHTIYLSRPMPLTKGEPSIIDLSEARFGESKHIDRIMPSVYRAPEVIRGLPWSYPVDIWGFGMALWDLFQPKHLFRPQVSGGPYSEAHHLAEMISIMAPPPLDFLRQCGEKADQYWDKNGTWKNLAPIPDTSLERMDQRLEGEEKQRFIAFVGKTEGVYWNEWLLADLIESGEIGREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMZ2</accession>
    <name>A0A6A6NMZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMZ2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="350" mass="38560" checksum="92F0C9CA93EDA6E2" modified="2020-06-17" version="1">MTDPTSNDMSSPLQTAHPSQGGGEEGALPDLQGRYISLLRNSVWSCCQCNREQPFRYDETSTLGGLLCQNPRCAWWAAPQHAACYKCDFTEQDAVELIRAPTFEAPAHPAQASTVGRTCCRCGHSWAVSAAARSAAQPPEPASRAHTFPSTACGKCARSTCDACLRWRLRDSWDEMYERYMGPRRGGPEARERGKTSPSPPPWDLDGTRADPDPGAGGKRAALSDRDRRARKRQRRIYGNERRVRWAAPTVHRWEEPGGRAGPPQLRRWLYADHEASELANAEDAEEEDEEGSESDEEATSAQEEEEEDFEPAEEVVEDDGRPPVAAAARMQADPEPSSGNTSSTPSDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN16</accession>
    <name>A0A6A6NN16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_149612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN16"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="181" mass="19910" checksum="3CE66A72FC30518C" modified="2020-06-17" version="1">MCDVRPRTPSKTTLEISIGWPGTQSAVRCRVVWPDLSCEIRRARLLPYRRGGWTRTDAGVRKGGNWLLRAAWHVKWNAAARAREGDGLLSVENGSLGKGVGEKLGTGGGTTRSEVIAPISGRQVRGAERSVFSRARRAGRQARWPLSLMLAVGTMTGGWFGRALWRDATSARKYQVRQHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN89</accession>
    <name>A0A6A6NN89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN89"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="22469" checksum="59C5539660EA1611" modified="2020-06-17" version="1">MPYRRVNGNAIPMIPDYISPKLWAQHLPIRLGDAHCSVEELQKEYYECHDRLNSTWVPKMVGVFQYLEEMQEHVKSYVILLESQPDCRSSLSTPLRMPWLTTTTSSITSSVNYPPSNALCKSRNVFYTSNIPKTREMVKDIQKGNAAKNSELGELRTMVLQLQLELATKTNKESAENVPSKQESAKCRKMTKSLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNS7</accession>
    <name>A0A6A6NNS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_357448</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-nitrosoglutathione + NADH + H(+) = S-(hydroxysulfenamide)glutathione + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:78371"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:145544"/>
            <dbReference type="ChEBI" id="CHEBI:229723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="12"/>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNS7"/>
    <dbReference type="OrthoDB" id="417550at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000001">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="14">
        <location>
            <begin position="34"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="13">
        <location>
            <begin position="208"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2452953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="40554" checksum="FA771B664D4808CF" modified="2020-06-17" version="1">MSTVGKPITCKAAVAWEAAKDLSIEDVEVAPPKAHEVRIQIYYTGVCHTDAYTLSGKDPEGAFPIVLGHEGAGIVESVGDGVTSVKPGDHVVALYTPECRECKFCKSGKTNLCGKIRATQGKGVMPDGTSRFKCKGKDLLHFMGTSTFSQYTVVADISVVPITDKAPMDRTCLLGCGITTGYGAAVITAGKGGIEPGSNVAVFGAGCVGLSVIQGAVKNGASKIIVVDVNDAKEEWAKKFGATDFVNPMKIGGQSIQEKLIEMTDGGCDYTFDCTGNVHVMRSALEACHKGWGESIIIGVAAAGQEISTRPFQLVTGRVWKGCAFGGVKGRTQLPDLVDDYMTGKLKVDEFITHRAPLANINKAFADMRAGDCIRCVVNMREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPP5</accession>
    <name>A0A6A6NPP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="14">PAGM</shortName>
            <ecNumber evidence="4 14">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 14">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_128067</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14 17">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 14"/>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPP5"/>
    <dbReference type="OrthoDB" id="1928at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000003">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000013">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000023">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 14 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 14 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="19">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="19">
        <location>
            <begin position="107"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="21">
        <location>
            <begin position="185"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="20">
        <location>
            <begin position="304"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="18">
        <location>
            <begin position="459"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="15">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="17">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="379"/>
            <end position="381"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="504"/>
            <end position="508"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2453273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="540" mass="57774" checksum="C7197D9566F2AEEE" modified="2020-06-17" version="1">MSAYEKVPAASAKFPKPADRAFQYGTAGFRMKANLLDSVVFRVGLLAALRSRKLNGQTIGVMITASHNPPEDNGVKLVDPMGEMLEASWEPYATMLANAESDDALLSTYESLAQTLNVSASTPARVVYARDTRASGSRLVAALVAALESVDTEATDYKLLTTPQLHYIVRCLNTAGTPYAYGEPTEKGYYEKLAGAFKTVMEGKNGGTVTVDCANGVGGPKLRELIKYLPSKEQGGVDIKVVNDDVLKPENLNSQCGADYVKTQQRAPPSSKATPLERCCSLDGDADRIVYYFVDSDSKFNLLDGDRIATLAASFLGDLGRASGLAEQLKIGVVQTAYANGASTTYIEGTLKLPVICTPTGVKHLHHAATRFDIGVYFEANGHGTVVFSPAALKAIATYEPKSPAQQHALRTLTALTELINQTVGDALSDMLLVETILAHKGWTPADWLGTYVDLPNRLVRVEVRDRALFKAVDAERKLESPPGAQASIDALVGKVRKGRSFARASGTEDAVRVYAEAATRGEADELAQKVAGVVKGFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ25</accession>
    <name>A0A6A6NQ25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ25"/>
    <dbReference type="OrthoDB" id="3796964at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="36267" checksum="3C6687054EC80B51" modified="2020-06-17" version="1">MPGAKSCNRQHAPIQHISDPMTKCRCGARLPRLPPDFLSFEIQKLRRHGYDPVDVAFWLMAASGHRQHPAGEPRARIDEGARLTRFAFIERNHHVHGADPAAMRAVLEHVARDLNGALFNGYLEVPAVRWERERAPRLEDDVWVKGRYIRETNTIELFEEGLLRDMNVPRVLGALVHQLVHAFLTQYSCKASQCQRWYETELCMGPDGHGRAFQVLAFFMEKMCILMFGDPEFDVFGEMLKMLHPYKATVKEDDAVEALPFLFGDTELHERYKLTSEDLGLQLGRPPIHSSRLGNPFVQGIASNPLPRRLGKRPEHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ51</accession>
    <name>A0A6A6NQ51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_292207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057283">
        <property type="entry name" value="RGF3_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF1">
        <property type="entry name" value="RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23582">
        <property type="entry name" value="WHD_RGF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="786"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="1258"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1096"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="436"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1098"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1593" mass="174728" checksum="CE1A4400F6E5EB1F" modified="2020-06-17" version="1">MSYNQNGQYYNSAAGYHQQQHHATSGYHHQQGGGYGLRRTSSFDNGDDAGFGAAADERRGSDRSNTIAGRQNDELFMGSMSPHGSGNVSSSGYSSDLHHHGSQSSQHQPQGPASPQTIGVSRTQSAASHAPYNPAAYVDASQRNAAGAGGAGAGYGAHPYSFSTGTYQSYGSPPAPQYQTPPLAQQPFAGGRSHHQSLPSPAALSARSSRHGSSNHVDRPLPSPGYPSDPSLPPTPGPPPPPHVQYSPQRVQSERHPQGRPLPGRPQNSDDALNYVNGPNGSPRIEVENSTSTLRGGHEQASQLPYPTEETGPNGFPTVPYEEYSTSDESDPEAAAGALAFEEAERQEQEDRARRESGQSALFSSYTSERPAEPASAGGGSDSDYAAHGFDIGAFGGGFEPHHLSYGANLVPAQTSMNGADSHSQPVSSSGSVQQRSRDASEASHRDPIHPFPPFQTGATTDVYGTGGLSEPTTHPRRLSFEDDDESGYTGGPEEIFFHPGPTNRPLPPPPPSSDGRPSPASPAWPQTYGRHYPSAPDAYSPSVTSTSATYVPRSQSLLSTGTGPPAAIPSRSKTDAEQYRIQQQQQQLRRSAMLNNGSTEALSPPSETVPIDLPAIPNKRFNPQKLTTADFRKCAEPWALSSIIAWMKFMTDGEAYLKEQAILDGLVALFTNKVPTMNVADAETLSAGVVEEMYKAGTLKREEEWLKFTNATMNGVLFQLTGTGCYAPMLHNFKTPGRCYSFHCQRTLKKIDLHAQPSVRQVEDWQTYYKIKKEDVEGVNKKEVERQNILHEIVQTEDNFMESCTVLQVLYRNSLLAAKPPVIAPKHVDGFIRDVFGRIDPVKKANEDFLLPQLKYRQQEQGPWIVGFSDIFREWIRKAKSAYIDYAAAFPRASFIVRLEAEKNMLFRSFLDNARNHKMSNKLSWDTYLKAPITRLQHYGLLLQTVLKRSVLDSEEKRNLAVAIEEIKVVTLECDTKVAEMQRKVDLQDLQTKLILRPGMQRVELNLDHLGRELIFKGDLQRAGGSRFNWVDIHALLFDHYLVMAKTITQKDAEGGTKHERYDVSRLPIPMDLLVLESANDEPVMKSSVKGIATARPSASNVPTARSSTSVGGGPGPLVHTNTSSSVNSMTTTSSGKSSLVASTVLEGPKDDKILYPFRIKHLGKETYTLYAPSAANRLEWSEKILEAKTKHAAALFAQNAEPFRLRVIADSAFAYDSGTAATNTRSVVIKGTPLDRAIDEVERLFQNSGRPGPICRAKVNCATAFMQPYGKHMVAVGTDYGVYLSEIDNPRGWSRAIPIQRVTQIAVLEEFSLMILISDKALIAYHLDVVCPVGGVPPGNDSARKAPQKLSGNRDVGFFATGKMKDRTLVFYKKREGISSTFKVLEPVFQKSTEKKSRLFRSGRTEFFREYDEFYIPTECFGMNLFHSSLAVSTSKGFEVLNLDKKHSWSVPDLKAPHVATIASRLAGQDPLGMFRLSDQEFLLCYEQCGVYVNKHGEVSRSVIMEFVGRARSAAVYGPYVLLFDPDFVEIRNAQNGRLRQVIAGRDVKCLDDALTGGTAGQRSIKISLQHPGLEKVQIVVELLLNEGQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ58</accession>
    <name>A0A6A6NQ58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L22e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_292735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ58"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="116" mass="13469" checksum="B42420D5E426B514" modified="2020-06-17" version="1" fragment="single">KKGQKITKKYIIDASQPTNDKIFDITAFEKFLHDRIKVDGRTGNLGDTIQISQQGAGKIEVIAHQEFSGRYLKYLTKKFLKKQQLRDWLRVVSTSKGVYELRFFNVVNDEAEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQW4</accession>
    <name>A0A6A6NQW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_355076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQW4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="50" mass="5749" checksum="0117CA15BA759D95" modified="2020-06-17" version="1">MMAVPLAFASRQQVMKLMSDYEVTLVNDNMSVYILPHPIPRHILFLRSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQZ0</accession>
    <name>A0A6A6NQZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_115119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQZ0"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046670">
        <property type="entry name" value="DUF6540"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20174">
        <property type="entry name" value="DUF6540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="130" mass="15073" checksum="AC0391A6566AE4CC" modified="2020-06-17" version="1">MSSYPLFIVTYDRGERWDDGTKKPFHWVFFLKTGNSADESLAFQLRGMPGAFYYSGEERVNINSSGSKKEELEIGAVPQNKYARFKQLLAAAPITKDESSKWNCQDWSLKVLDWLREEGFVEEQYQNNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR79</accession>
    <name>A0A6A6NR79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoinositide phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_400224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR79"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="128"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="757" mass="83252" checksum="7C7C2F047C115188" modified="2020-06-17" version="1">MTSTTASRLPFRDINVHASPSYYAFSSPSSPSAPALVVERPSGDLRLDHDGKATRGGGLSGVRRVSSIAGILGVVRLRLDRYVIVITKAQPMGRLKGHMVYKVAATELLPLRERPLHDPDEDGYLALLRALLRQAPLYFSYSADLTNSFQRQAAADLSQPLWRRADDRFFWNRFVASDLIDFRDGSSGSGSGGGSMAFRHALGPQPDVDPYILPVMFGMMRIAPTAIKGTPLTFVLITRRSRHRAGTRYLSRGIDERGHVSNFNETEMVVILNDDAQGGLGGFAPGQFQNGKLGGGAGGADGRETQVLSYVQTRGSVPLYWAEVNTLHYTPALQIRGVETAATAARLHFAEQIRLYGDNYLVNLVNQKGRERRVKEAYEQLVRELVSTPAEHTEPDSAGITAEKFHTVEPRGARGARGRGGAGGDEPIAFDRLHYIYFDFHSETKGLRWHRALLLMDQLRDAVASGGYFRGVDMPGGRSSSGRAAAGGEETRLDVRARQRYVVRTNCMDCLDRTNVVQSMLARVVLTRMLHDAGCLRAGEAADDDAAFESLFRNVWADNADVVSRAYSGTGALKTDFTRTGKRTRAGALRDLTNSVTRYVLNNFGDGPRQDAFDLFLGAHVPDDEAAGAAAPPAGLFVDTRPVAIQAVPYVLLASVFFVLVGSLTRRPPDATVWPLRLLMLVFLVVGAICAHFMWTHGTLYVNWPKLNPPPWVQENYLEALSRVRSTPLLGPLVIKHERGRSEARMSYLEEGKKRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRG6</accession>
    <name>A0A6A6NRG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_423882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRG6"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="79"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="344" mass="39664" checksum="93808AFEA05A6618" modified="2020-06-17" version="1">MMLALCRIIMEFRTPKAAEISTNKTADPAEKDADNREHCYDALDQPSEQIRVVTVHPGDFADPIVCDLQLVFLDDKPYYEALSYVCGESSATRSIILDGRIKQVAVKLEQALRRLRKRDRPRIMWIDAICINQEDKEEKGHQVALMGRIYSCTAEAVLWLEHDADLENTNSEGLPAEDEVNEIALHGDERDKELLDSIYFNEPLDEPLPISDYQRQGIGALGLFVLLLRQHFCKLPGMEFVDGHLWLSDSFVWAYGSLDAFTFRPWWSRIWELVSNRNSRDSLRILPTLAMFRGRDARDARDKIYAFPAFDAETWQDILIISDYSMGIQELFILLYINFFEATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRK3</accession>
    <name>A0A6A6NRK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5402622at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038769">
        <property type="entry name" value="MTC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38426">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38426:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="893"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="984"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1124"/>
            <end position="1136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1305" mass="142948" checksum="3CCC6E25AFF6B0B2" modified="2020-06-17" version="1">MAADAQSTASAASSNTLHSRQSPYDQQNAEPGSSQPRRSESSARSGSTAAMEWTPRNGAHGPRAGATEAVDGPSGRAHGRHSIQEAGHASRGHRPKRSGGFLLDDFGNAFGDPRAEKEKGSLSVKRRSSGGRSHAGQRPAPRGAPLNGSPLSRQMLTPEDAEGHGQRSQMGNEDPSHQRNASRSTTPEPPSFGPAPAINPTEIVNLALNLSDARRRNPSGGHVGPMPMNSSRRVQSAGYPAPPSTPMHGNNYGYGVGGSLRQHLQQQRRISRNLSPGTGRRTPSRQASGPKPASHIEPAVLLQQQGQDAQLQFSPATLARAEKARRFIELGIEYRRLLQFLPPLRPDSAAPGNHYVSASSVPGTPNVELRKVPSHANKKHELGRSYNPLQFVRNRKLRARERKPMNPDSHEFHDVTRVKQWVDEVGRASEMHGYRQQDYVALPSYGGNPATVGPTKELSEAPHQPSKPKRPPKDWFTSPEELLADSYWLEQENNKMLIEDRHGAKIYEGEGGNAFQLTRSSQEIPRDTDKKRGSVGTSVKIVPPQEIEATEDSDGDANERGRKGRRFLHGSSEDSRSRVKKAARHIRGRSPSSEGLSSSEDEGDGSRRKTKASVVFTPDQENIGPLEKRMEEMLQNGAVNDGSLSATSVYSPDTPDKWGVGHTALSGQVVEPRTKDEGSGSTNGNGKPEENLKTRKTPPSNLLVIPQTADSRDRRGSMDDLDSTAPNTPIKPSLAPGITLDLSPPASRRESPTRKPKKSKLAFIRSEISRDSNRSSEHSESVVDDSDAKSVQRFDTAEPYPVTAQVSRASTDKSTAPSLKQPLSHRTTDSLTSLSRPDSRGRREGKEARDTRDSSSMLSKFFRAGPGRIGEVVRTEGSKVGDLIWKRGDDAESSSSSSSSSSSSDSSDSEPDRRHRLKRRPKLRKRTTTEQSLTIPTKSIKPKHMDNLPAFKSTRVESIPVSSEDVRRGSSPFDRTRRGRSYQPGPQDTDTDSQTHSPLSPNPPHAHDDGGKDDRRRSYGFLSVPSRRRNDKRDDMEPVDRTESNASTAEASARLADVLGVAGEGAHREPPVTGLANVNLKRPSLNGRRQWSITDSRSNSRSKSRDAPYTRSEQASIDEQLVKQQQQPVTRPTPHVTRTEIARTRALLICTSIKAATILQRANSVRHPPPPFLAHASDTGARERLLREGADRFVLDSIPRREEHVVATRILVDALDGHARALRASQAEFVQRRMHGPDGAHARVGSLRRMVDAELSPRVHACADDADALAGSVVAGELAREVQAVSERAERLARKRRRGTRWSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSD3</accession>
    <name>A0A6A6NSD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSD3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="101" mass="11087" checksum="50A96CD153225B4D" modified="2020-06-17" version="1">MAQEPQPPYSELDTVGRTRNWSNTAGRSDRRLRRASLRPFSAIPGDGIPGGGEFGPRTSRRTLTLRSLRLVILHLQLVALGHDSKQKCPKLGSPKKSCGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSK3</accession>
    <name>A0A6A6NSK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSK3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="7375" checksum="A0373758FB87B49D" modified="2020-06-17" version="1">MGPINQQTCTHYESYATTTSFTDCEGCVLATMAMGPGPVVQCGTWVTEPVSSMTVTECFPSPTTAPSPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT16</accession>
    <name>A0A6A6NT16_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT16"/>
    <dbReference type="OrthoDB" id="2827561at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025400073" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="16996" checksum="1E940CDB30F6BC57" modified="2020-06-17" version="1">MYTKYFTSAFFLTLLGQSQVASALWGCPDSGSRAGKFLIHYTPARNSNYMNPDSGCHGGGGDYDSWVRICLPKNDGSYSQIHARGTCCGSGHPKTLHPDQTGLPKDIKIHNGHGCSTEGANANLDNLWITYRGTLHNVPDDPNCSDPDHGSTCEFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT24</accession>
    <name>A0A6A6NT24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_96216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT24"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17866" checksum="F705FFF1048B5501" modified="2020-06-17" version="1">MSYAYIFCFNNFVTDSKVCISKRFVGWCPSMKSKSRDKISRRGSFQRGVTAICYTCSHSTLPLLQSQRDIMKSLSKPTNPSTSNTLTNTPYLCSTPGSLHMSADNYTPGNHTKEEKFLHVLSRSTPISHTTKRHREEGFLAREISFSGAESQIATGNAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT86</accession>
    <name>A0A6A6NT86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_308564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT86"/>
    <dbReference type="OrthoDB" id="684045at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000248">
        <property type="entry name" value="Ankyrin repeat and BTB/POZ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044515">
        <property type="entry name" value="ABTB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="343"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="633" mass="71394" checksum="63BE9BD48BA6CDDB" modified="2020-06-17" version="1">MVRKKHEIEAALHAENQEIKAGRLKEENPLDVSPDFEVLCEACRRGDLKLIQEKISAGVNINARDRFDYTPLILASLCGQFEVAQLLLESGAQCERDTFQGERCLYNALTDRLRNLLLSYDYSKATHSVQPLAAHISALLTRNFPQTSDVVLVSVSESIQAHKFVLAARSPYFARKLATSSSLCSLRLSDAVPPQPLKAAVEYLYFEDVQRFQSPSENEEDFLNGLARVERLLEIENLFENTLDSVDRRVARQKREEELERGQNQLEAWFRENVIANKIRVNRGQAPKVRWNRENSVFADVLLQADEEEHVPPQNTSDLNGGDRASAPANSATEIANTKVSQEDIRQFSGSSRKSVLFPAHRAMLIRSEYFLAMFSSAFREAQDSDYLHVIKVACSPEVLEIVLSFLYAEKADFSLEIATDVLFAADLLFIDKLKVKAATVISTLGYGNASTTEATNPRGVTDSDDVINIYDIVRAGWATRVHRLEEFGARYIAQRMERFIDEEEFEELVAESAGRIQHRQETDTVELIDDIRYYLSERFRLRFEDSGLDEMMDETVSSAEQATPAPEEDASDDAAAETQQIYAPEVDGRLLPGAVRTLDGEAAGDEFTQDAINYQILLRKIDDLLDRLKLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT87</accession>
    <name>A0A6A6NT87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_373670</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="5"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT87"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="13">
        <location>
            <begin position="19"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00071938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="354" mass="38772" checksum="06DC2185AB4CB03E" modified="2020-06-17" version="1">MATVAQDIFKPTKFGGKYTVTLIPGDGVGAEVSESVKEIFKADNVPIEWEQVDVSGMEAGSKHSEELFRESIASLKRNKLGLKGILHTPVERSGHQSFNVAMRQELDIYASIVLIKNIPGYETRHKNVDLCIIRENTEGEYSGLEHQSVGGVVESLKIVTRAKSERIAKFAFAFALANNRRKVTCIHKANIMKLADGLFRNTVKRIAEDYPTLEVADMIVDNASMQCVSRPQQFDVMVMPNLYGGILSNIGAGLVGGPGIVPGCNIGREIAVFEPGCRHVGLDIKGKDQANPTALILSGSMLLRHIGLDDHANRISKAVYDVIAENKFRTRDMGGNASTHEFTRAVLDKMEAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTB1</accession>
    <name>A0A6A6NTB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_291366</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of a tri-snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SNUT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTB1"/>
    <dbReference type="OrthoDB" id="21368at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013957">
        <property type="entry name" value="SNRNP27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077">
        <property type="entry name" value="U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077:SF1">
        <property type="entry name" value="U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08648">
        <property type="entry name" value="SNRNP27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein" evidence="8">
        <location>
            <begin position="12"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="66" mass="7669" checksum="8BACD95EC1E331B1" modified="2020-06-17" version="1">MDVDDEGMDPIEAEMRRVMGFARFRSTKNTKVPGNDKLYGVRKEKKTKYRQYMNRPGGFNRPLSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTD9</accession>
    <name>A0A6A6NTD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_324861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTD9"/>
    <dbReference type="OrthoDB" id="5138418at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303:SF2">
        <property type="entry name" value="COA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303">
        <property type="entry name" value="CYTOPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA-binding" evidence="2">
        <location>
            <begin position="34"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="182" mass="18557" checksum="4E31250536927861" modified="2020-06-17" version="1">MAEPSPPPRSTTNPDAATPPPQPAETMEAALRTFFSSPRFAVAGASSDPNKFGHQIFKWYLAHSLPVAPLNPSSASITVARAAYPALASPAALPNPAATALSVVTPPKVTAALLRDAAAAGVRAVWLQPGSFDGAALAFARGAFAAAVAGEGNVTGGEGWCVLMDGEEALGLAGREWKKVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI4</accession>
    <name>A0A6A6NTI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="182" mass="19399" checksum="512890A326F39512" modified="2020-06-17" version="1">MGHTGGLIRIIRCVGPPQVAPESRPGGKSELSPGGSLVAEREPRRQRFAGIGSNLPLMIGVLQYVLVRRGGEGKLAEDSGDAGLAPVLALSDPGERRWSCHRAPRREWATRRSGPKRAVLSSSGVAGRRAANLGLRPRRSVVEEGRNCALRVARGALSGSRHPRRVLRCAVLLLPACLLVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTK7</accession>
    <name>A0A6A6NTK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein Het-C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_352249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTK7"/>
    <dbReference type="OrthoDB" id="2506204at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025513872" evidence="2">
        <location>
            <begin position="29"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="950"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="682"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="918"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1005" mass="109603" checksum="D15BDCD52AACD871" modified="2020-06-17" version="1">MAPARLSLSSVLIPCFLLLALCAGQAHAFGAGNIASTAKIEGQNWRHGDIEDTLLTLLMTSASGGKKFGKMDVKRVYFGNWLRDYSQAVDVGTLKMVSSEAIRILLWVLGFLSFGFGTGEFEVTAERLGCYRPEEHIDNPKDYADNIDARQYDPRLRGPVDERLELSVDERTGLKNYIASEDLGITTSAGLVRDLFRRSVKLARRYHRNGNKADFYEALRLLGTGCHCLEDYSAHSNYTELALIELGEHDVFPHVGRDTQVEVRGARGPIYPLVTGTFGGVDFLHSVMGEISDKATQSEVQQLEGTIEQSATKENASVVKDLLSQLPDGLFGGKDEAAKADELQENSAAAQMENTHITPQEPEAWAEQLGEISKQIYPVLEFHDEIMLGITETIEKIPVLPDLIEELQNQVNIFIFSLLAPYVLPIIRQVKTELATGSSEIIESSREKQLIVFHDDYSSDPTHSMLSKDHFSNVLNEPAGKIASAVLKWVVPQIVECWDDEDVDEERTIHRIVNGVFHHPALCRYGEDGAADGRQIMFRVVQDWWESQSSREQDDLRDKLSRDGVENGRNHKEGVHDQGHGCGKPIGMPTRDTAMSTGILGSGKGGHGGFEGQAMHKVGKAAGEAVGGGALGGIVGGLVSGVGSSLLGGALGGDDSEKKSYKHEGYRDDGGYEQSYTETARRSSGYGSSDRYGQAEYKTTDYPSGHHREEYSRYEQDSRGQGEGYGFQQRVEERGGYGGGYERSEERRYEAGEEWRSETQTEGVGRSGEYYSHESHHHGHHRKKSSGDSDEDESSGGSDDEKKERKRREKARKKREKEERKRRERYERYGSERRSDHSDDSDEEKRYRRRSGSGERSHAYSGGYGEERKYGGASGYGQESSYGSGAYGGGYGGQQSSYSSGGDYGGGSGYAREASSYGSGGGHGSGGGYGAGGGYGAGGGYGAGGGYGAGEGYGERREYGSGYGGESGEYGSGQYGQGGGYGGGYGGGSGYGRSDEYDEYGSRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTW1</accession>
    <name>A0A6A6NTW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_351462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTW1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="274" mass="28594" checksum="E97ADDA30B631E37" modified="2020-06-17" version="1">MSGCLFWHLGHIPTSGDALWPVVKGKVVRLGIKPALAVCGDQALTIAIEIDSIFVVGARECGIGAIRLVVRRAILINPRAIEDAELIHGAVMNDAATESEVRVDAGIGRRDALSFSSATRACKQNVLRHNNSSSRDNETHLPGIQQSQKPLRAPVGHAIVTPVPHAPKREAKRLLAAAPLVAEGQARPQPALVPRALLVPLRPHRVVAPRAHGVQFLGARDPAPQRHRRHDREPHVGALGAEGAEVAEGVVAGVALVLGGEGAGGVGAGDGACG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY0</accession>
    <name>A0A6A6NTY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_290082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY0"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="11884" checksum="F2AB8F448F557DE1" modified="2020-06-17" version="1">MSTSASGNQIIKVGQDGLTFEPDTLTVEEGDMVEFHFWPMNHSVSMSTFDEPCVPASDDAFWSGFMPVEEGMGDDIFVVQINSTDPIWFYCATGRHCENGMVGVINPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTZ4</accession>
    <name>A0A6A6NTZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTZ4"/>
    <dbReference type="OrthoDB" id="2120024at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="112" mass="12681" checksum="83D87FAAB161FBF9" modified="2020-06-17" version="1">MSSSRVLRQARRAGLIHPLTPSRPVRWGSSYEPPNPTPPQPGGGNPHRNFYKSFGRPVAKVFLGSMFTYQLLYWSWLKLEAVEIKKEKTAELNSLQTQLEQIRSTKPTAAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU01</accession>
    <name>A0A6A6NU01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_96904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU01"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="177" mass="18943" checksum="E7DF2ED063BEF4B2" modified="2020-06-17" version="1">MFENTGRASKAQERNRALPKNSEKAVRRPAKQRIKGAEEGKEGQAGGDDGHLRGRREGSPKASHLSHQSPHHSRPARPLGPLFGLPHESRKGTSRRPCAQQESLTTDGIPGSAATMRVCGVCDTPSWRRAETPASQAATLGGLDAIWGKVQARGPGSPFSRRIHETPSPLPGSRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUS9</accession>
    <name>A0A6A6NUS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_66370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUS9"/>
    <dbReference type="OrthoDB" id="2400485at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21431" checksum="9155B8426EFE3D71" modified="2020-06-17" version="1">MTSPGNTGANQQLPQAFEKRPDSSALTGTSSKDVDYEPYPSQSVPLDESQQQIVESICNLYSGSASESDMQVYADSAVYDDPWSYCDTRYKIAGQWYGIPKVFASSATLRTQIMSATPTEIVFKLQQEYTPRLAPTGKAVNSLVTLSLDENGKVRYHKDMWNEKDYSHEGLGKVFKTLNGDHLTKITKPPDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUT3</accession>
    <name>A0A6A6NUT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUT3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="21105" checksum="4A7044B4B35AC8F7" modified="2020-06-17" version="1">MATARSPASDCTSVGCVCTLLVVSARPTFPGLAAQRPQSNTSSLAMALHAGQTTLVILLHWRHPPNTSPVCRFNSGIKPAPGSCSQSKRVLGKLRSQESHASISCKLQKRHVRQSPASARTTEPGISCQSAEVRRLFHEKRGFSGDGFRALVRPDSLALFGVEFLRTDELALFERRLVSFVPLVLVCSIALRARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUY7</accession>
    <name>A0A6A6NUY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nuclear condensing complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_422865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUY7"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="639"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="583"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1011"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="583"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="745"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1011"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1026"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1080"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1092" mass="119522" checksum="5FF21653729FB0C9" modified="2020-06-17" version="1">MPGRVSTRNSADSRKLSTQTLKSRTSSTRTSALAVDIPDEGEDTSLRARICSIFSDAQRNVATQRKLVISLRKLHEECCYEPVNPPKSKGRATEEDFGETEFNEEIGRCLLRVLTVKKSEPVGDRSVRFLGQFLKHASEKDNAIAQPDADTTDAFPETPASRLTSYILNLLLPLLVAKDKTVRFRATQIISHIVNTLDSIDDELFQLVRLGLLKRIRDKESAVRVQAVLGLGRLADDGDNENDNSDDSDDESSGSGILEKLLDILQNDPSADVRRSLLMNLPFAPATLPYLLERARDCDAATRRALYSRLLPALGDFRHLSLTHREKLLRWGLRDRDENVRKATARLFRERWIEDCAISRLPDEEGAAPPPGQLSAPNYDALLELLERIDVVNSGVESGIAFEAMQAFWEGRPDYREDISFEDPFWDELTAESIFVARTFNAFCRHSGDSMVQSMAEDKMPEVTKFAFILQRHLNVLIEGVQKVALEQDPDAEEDTVQQEFAVEQLLHIALTLDYSDEIGRRKMFSTMRESLAMPELPEECTKLVIEVLRMVCDPNPAGEREFCGIVLEAIAEVHDTIIGDDSSVKDESFHSARSEMSDESTPTKAKKVKKSKSSSSEDGEEGAQDEEKAVREIMVNMKCLHIAQCMLQNVQCDLEQNSDLVTMLNNLVVPAVRSQEAPIRERGLLCLGLCCLLSKNLAAENLTLFLHCFAKGHEALQAIAIQIISDILITHPSLLAPLPPGADTTTASPTKSPSKSNDPQANPLLKPIYKLYTRALSSPHLSVQTPATTALSKLYLSSVFKDPALLHSLVLAFFNPDTRANPHLRQALTYFLPVYCHSRAENQLRLARVAVGALRVLVGVREELEVDGEGAEEDMVGLAVVAGCLAEWTDPRRVVGFSSDGAAGSGDASKVVSGDVNAHMLLAEDVLERVGASGCGKEERKALLTLLAKLALPNAAPPAGSPAAEALGRIVASTEEALEGKAAADATSRNALNKFHCAVTKLVGAIETSEAGHEETLMESVERGGDDEEGAVMDDDTALPAPEAEGTIMPAGDLDDAESTVIDSGRNGRISREATITDDTVDSLLESDENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVD0</accession>
    <name>A0A6A6NVD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_348480</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVD0"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="698" mass="77242" checksum="79D7C95379B4FBD9" modified="2020-06-17" version="1">MGRPVAFGVEDVQPLEEQMDTRNESAAVRATEAEPAQPKRKKRTPMSCDRCKSRKTKCIGPVPGPCQYCASIGVRCEIDMRARKKRPFYHVTEEEYRYMVQILKHQYPGRELNLHTLRELARELDISAADTGESNPSNPNDGSSTNDDLQGSPADDVANDEIRGLYDGLGSMIVDSRGKYRHIGADSGISFNGAVRALTEGPQPTTEFTHPPEIIQPMSTTSLPPTSPESSMSGPSCGVDRGLPLALPMREQCEQYVSLFLEQVHGLYWLYSAEQLHQEVEHIYAVEGDKRVSAACLCGLYAIFALGAQDEETEEVDGGVSPTTAEYLERAKTLVTRVCDQADMESVKALCLLSLALQSACFGTASYLYVGTAVRIAYSLGIQLDKMPPSQGLIEKEQRRRLWWTLYVLDQDSALRCGNPCAITVGEMMPPVPFPSERVLSAPVPGLLQQMASLSHIAKQVSRTLYFQPTSSTRSISFGAVQSLVTSLQSWQRSLPPHLQMHTPVSPSHRRAVGCLHIRYWSVVMLLTRPFLLSTALPGARLSCEKQRSTFETLGHMCIEAASELLGEAREMNSSGCLSSRVYFDCESLLQSLQILRLALVKTGDTIYREQVLSCVRILESMEQFGWPRRVLPEVRHQLRQSGIMSRDESAEAPMTDMIGGSQVYEEGLEQLELDYGSGLAAGGFFLEDPIDQPSLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ7</accession>
    <name>A0A6A6NVJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_60037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="17889" checksum="564FB39B56B12EDD" modified="2020-06-17" version="1">MALCFPIRSTPYGTRNSTCPSLCAKFPYCLPQKGTHKFADFTSRVLPGVARVPPEIRVPQLAFPASALTLPNFGLLVGLFWTRRSGIPIDKAQSPPSICTDVGRFSLGGSRNRLRLRVAHSSVLTYSRIRSAYYVRPAYVKCISSQDSLPTFIYAIRGSQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVK8</accession>
    <name>A0A6A6NVK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVK8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="51" mass="6042" checksum="FA2B3F98B24CDA48" modified="2020-06-17" version="1">MNPRDVWLLHSLRGLDFSQSRFANPIPLRDIEVRSLKLHNGFHFVLAEERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH7</accession>
    <name>A0A6A6NWH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_372956</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH7"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="13"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12665" checksum="EC88E58B3BF5516D" modified="2020-06-17" version="1">MGLAYNIYLNSHRIYGCKNCKTHLSNHDDIMSRNFRGQHGKAYLFENVVNITAGEPGERNMTTGRHVVRDISCRQCKEVVGWKYDKAYEASEKYKEGKFILEAELLCTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWM9</accession>
    <name>A0A6A6NWM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_57258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWM9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17150" checksum="10A6EB373C36AEC6" modified="2020-06-17" version="1">MYKRSISRSSTPPATNGAGHPSKASQQHPVATVLPPTCLFFPFSILCNPPCVPFYYSQLASFRQVLSASGVLAVAPLSSIHSLLQHSTRPFQICLTMAQSSSSSTSTTTFAPMPSAVSTGICRISTIPSQMPAHPTRIRRGLLFRMAELISCVPGVESLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXA7</accession>
    <name>A0A6A6NXA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_422699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXA7"/>
    <dbReference type="OrthoDB" id="5582218at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="27672" checksum="35FE8E8006A8F078" modified="2020-06-17" version="1">MDGPLAGTTTDAMHTKPIHSLTHHPMDLRRRPPPQPYRRATTPSGENLQARSFHFYWFLHCASHRIADARCSFPAAVTMPPSSSSASLGERACLTRILFSRHRRALIHTHLLSAARLPPLLRALRSALAPGNAFAPPRAAPPEPEQAALRRRAAERIVEALPPHVVRLIKPTPRAASRPGSSRGKVHYDGSDEKAVREAAVNEVHEVLGVLADQYLNRHVVFGIVELLVVRLMPEMAERGVEALMAERLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYK4</accession>
    <name>A0A6A6NYK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_266875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYK4"/>
    <dbReference type="OrthoDB" id="2017317at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="153"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="27"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="35543" checksum="24AB8150CC7B0E37" modified="2020-06-17" version="1" fragment="single">LPLLSPARLDRARADGPAAKPEPTVLYLAYGSNLCYETFQDRRGVRPLAQVNVQVPELRLTFDLPGIPYTEPCFANTARRRADGGDNSDGGDDGGKEKEKEKGERRWTKGLVGVVYEVTSEDYAHIIATEGGGSAYHDVLVDCYPLEHGRDTVPRTHPDVPPFKAHTLFAPRQDPDDPSSGSGGRLSRPDPSYAQPSARYLKLITDGADECSLPAEYREYLGALRPYTITTQKQRLGAFIFLSLWGPFIALVFALQEAFKDSDGRSPDWLVQLSGAIFAAVWSSYDTFFHDVFGDGERTMDEHDQSDRDVCARRGPARRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ20</accession>
    <name>A0A6A6NZ20_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_287294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ20"/>
    <dbReference type="OrthoDB" id="2596908at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="288" mass="30817" checksum="BD3E47DAAD4F0035" modified="2020-06-17" version="1">MQRRQQDGTPTNDAPVVSTTPQMGDASQIDLDAWEEQTSAACENALQSLNGEASNPSGMAVCYNLPFLDNETGVFQAELRVYNVSAPIPPWTGVSTQDITVALSYLGATVQNVNGTLQRRDALSWPSDDKLGELVRKQAASMDEVKVLTYVGQVNSNLMGSAMSNEQLQPLLIPSIVLAATAPDSGEIINTTLSSTEASFVNGVFADQATQTLTPESQISASQAAATATPFVLPGTTFGIFPTGFIVTMIWSVAFVVTVGLGTMGRIQFRDQYRRRVKREVAIGVANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ93</accession>
    <name>A0A6A6NZ93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ93"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="17459" checksum="1525D92E06373014" modified="2020-06-17" version="1">MPSQAIAPTIYAHDPITIFPDPCFPPAPSLRRKHGLVLAGKVPKAGIWRSDFLVWPIFFGLGGGGAGCLCYLLVPSPFISPSCCVPAVAARAAPLGLVGNALVVRCHLRSADSGQTPPGWSSKPPSSHCAAFSAFLRCRGAAPDQSQSSSACRVCSTRPTRMTCSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZE9</accession>
    <name>A0A6A6NZE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_371942</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZE9"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000009">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="147"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="7"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2457121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="329" mass="34399" checksum="6F719EBD7D863D2C" modified="2020-06-17" version="1">MKAVVAGASGGIGQPLSLLLKTCPLIDELALYDVVNTPGVATDLSHISSPAKVTGYLPKDDGMKNAFTGADIVIIPAGIPRKPGMTRDDLFKINAGIVRDLVQGCADHCPTAYILVISNPVNSTVPIAAEVLKNAGVFDPLKLFGVTTLDVVRAETFVAELTGVSDPSKTVIPVVGGHSGETIVPLWSLAKPAVNVPESKLDTLTTRVQFGGDEVVKAKDGAGSATLSMAFAGFRFAEKVIRAVTGTTGIVEPTFVYLPGVDGGAEIAKHTGCDYFSVPVELGPKGALKAFNVIKEVNDYEKELLAKAYEGLKGNIGKGIEFVKNPPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZI4</accession>
    <name>A0A6A6NZI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Asp/Glu/hydantoin racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZI4"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF5">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="27338" checksum="7A91A1FAB47F91CF" modified="2020-06-17" version="1">MRAEYSILVVNPNSTEAMTEALKPLTSKLGFKDASLTFFTAPSGPKSINNEDDAIESARHCLPHLLPLLAFNDAILVACYSAHPLVPILKREPSIREANKPVTGIFDASVSAALQLVQPGERFGIVSTGRQWEAILSEAVEAFLGTAAKQGKSSAPEDISARFAGVETTGLDATELHDAPPEEVRRKMMDATRRLVRKGKVGAICLGCAGMAGMNEIVREACLEELGEEEGRRVRIVDGVQAGVAWLEGAVRLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZR9</accession>
    <name>A0A6A6NZR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_32182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZR9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="19520" checksum="AA914272532A394D" modified="2020-06-17" version="1">MRGGASDSVDRNFQLRPAILGVHLLSHLHTLRNWAGILATAVRMKELRQAGSRSDPTSGGELGRGRDHVSFLIPSYCCLEISEIARQCFPWQSGEVDETHVGHVTNAWCGWSIHGEHAIGSSFLPCFFFKPFFRLFSMILLFFFLLFDSFGKWDMLWRGEHRVICRSLYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZT0</accession>
    <name>A0A6A6NZT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_392487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZT0"/>
    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025462152" description="G-protein coupled receptors family 1 profile domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="41589" checksum="EBBFD67031E9C693" modified="2020-06-17" version="1">MPPSWSACFAFCSLLASAASPIGAHAAPSAHPGFYYFYRHDNAASQQLDARDTEETGPVVDGDANPGHAVVRGENVNARTIYTVVSMTCMVILAWLLGSRAKYLRLRHIFRMNPTRLIVVIQHALAVAFVFCAAVVESGLGLSTDSSCFSAIIVCLVFYVLSKIVMYVFLVERAHALRDPFLSRAHDAVWVSFMLVVLTGFGSIATVAFVYPLHDISALDGKCRIGIPLKVSVPLLAYDIAINIGLTAVFIALLGRALRFDPFAHHAAAAPPPLPAPATGGPPPAADAPRPSLLSARLKASLGRRLAWKSFAGAGLVLIPTVANLGVLYYLNGREQGWLCFTVCTLDVTWAVIIIHCLTTDEVEMDGRAAGMNRMQEVTSSASIAVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0C3</accession>
    <name>A0A6A6P0C3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0C3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="15911" checksum="C286D0E85305C8E5" modified="2020-06-17" version="1">MQRATGRQKGRKAHRRNERSAGGRAGRKFGMVSGVRAWRFDGFSSGRARGRGVCVCGCGLRGRVGRPRGCGGSCAGRGRGRWAGDAGATDRSALLPEAASKQAGGLRCVRGRCSADATPLASWGALGTARCSGGGAPGLFAALLMAGCGHCGICTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0D4</accession>
    <name>A0A6A6P0D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor CWC2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Pre-mRNA-splicing factor cwc2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_372051</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM CWC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0D4"/>
    <dbReference type="OrthoDB" id="10251848at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000249">
        <property type="entry name" value="Pre-mRNA-splicing factor CWC2, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="19">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="18">
        <location>
            <begin position="182"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="306"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2457268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="391" mass="43404" checksum="7267068BE4152B75" modified="2020-06-17" version="1">MASPTATKADSEAMASVEPAAQPAAEATADGAATTTVATREGGKKVIKKVIKKKRRPARPQVDPSTFKSEPPPQTGTIFNIWYNKWSGGDREDKYLSKHHAASRCNVARDSGYTRADKVPGSYFCLFFARGLCPKGQECDYLHRLPTIHDIFNPNVDCFGRDKFSDYRDDMGGVGSFMRQNRTLYVGRIHVTDDIEEIVARHFQEWGQIERIRVLTARGVAFVTYVNEANSQFAKEAMAHQSLDHEEVLNVRWATVDPNPQAQKRDARRIEEQAAEAIRRALPADYVAELEGRAVPAKKRRVEGDIEVEEHQDPPSEAPQKNEPLRLEAPEQDMAPTLEELTAGSNNGILGASTLNMLENSRAEGMAFSTARQEAPKSSGPLVEYDSDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0E5</accession>
    <name>A0A6A6P0E5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-lactamase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_379863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3R)-atrochrysone 2-carbonyl-[ACP] + H2O = (3R)-atrochrysone 2-carboxylate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:64236"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:20479"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:234107"/>
            <dbReference type="ChEBI" id="CHEBI:234110"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:64237"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0E5"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000328">
        <property type="entry name" value="Lactamase beta 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000041">
        <property type="entry name" value="Metallo-beta-lactamase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="33"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="303" mass="33060" checksum="0CBB502E5073B2F7" modified="2020-06-17" version="1">MAGALLPLPEVERLSTRVIRVLGGNPGKFTLQGTNTYLIGTGPTRILLDTGEGKPTWPPLLHRTLASERATLSAAILTHRHHDHISGVPDVLSSFPSLPIYKHRPADVASWPGGPNPLDGLQAELHDIAEGQVFAVEGATLRAVRTPGHTADHVAFVLAEEEDAVFSGDAVLGHGTAVFEDLAAYMACLEKLERECGEKGRLYPGHGAVVEEGRARVREYIEHRRQRERQVLNVLETGKEGEGEVEGWGSMEIVKVIYKDYPENLHEPAQRGVLQILDKLIKEGKVAHHEATDTFSLITKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Q3</accession>
    <name>A0A6A6P0Q3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_385926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Q3"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036149">
        <property type="term" value="P:phosphatidylinositol acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="6">
        <location>
            <begin position="141"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="392"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="476" mass="53732" checksum="ED450A63C360F2DD" modified="2020-06-17" version="1">MNAEGLKKRHQRPDGGGGAAVPDGVGQSEKMAAGEMLHPGGPVKHGNYMQALRMFLFALYFFGSCCCILFSQLCGAWLYFADQDLYYAYMAVTKQNFGLLITTMTQWWSPTLVRVSGDASVRGQLHQLPDGRLECDFPSRLILVANHQIYTDWLYLWWVAYTARMHGHIYIILKESLRWIPVIGQGMMFYGFVFLSRKWATDKPRFMHRLRKLNSRHSGPMARAREEEEAAAEAEAEAAADPKADRGPRKPSLDPMWLLIFPEGTNLSANSRQASAKWAAKTAQEDMRHVLLPRSTGLMFCLEELKQTVEWVYDCTVAYEGIPRGQFGQDIFTLRSTYFEGRPPKSVNMHWRRFRTADIPSGDAPAFEAWLRARWREKDELMETYVRVGRFPADDGEDGPEAGPAGMNGEARANGGATGGPRAEKRGGKGAGYIETEVRPRNPVEVLQIFVPAVLGAWALARMAFLVVHRWRARRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1B5</accession>
    <name>A0A6A6P1B5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1B5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="11393" checksum="A4ED96427FEA4DBC" modified="2020-06-17" version="1">MFPSPVPGHTARRYRHRLAARRWADASAPQQQIIVIAVRRLAIRIGFLSLAGDGQGNGGATSVSHRCRSSFPGCPSTTAHTPTGPSARTSSRLPHLVSDWRQPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1H2</accession>
    <name>A0A6A6P1H2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Curved DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_285735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1H2"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000016">
        <property type="entry name" value="Putative curved dna-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="424" mass="46431" checksum="DDFF5A2B5773D4AE" modified="2020-06-17" version="1">MQPADGIRRPQLILSTDYSLSNPDTLTKYKAAGEISNKVLKAVVGWCVEDGNIVELCEKGDKLLEDEIAKVYKGKKITKGPAHPTTVSPSSYVTPYTPIKSDTEEAATTLKAGEVVKIQLGAQIDGLGTIVCDHVVVPNKDGSPAAVSERVADLIHATHYANELLLRLMLPPGLLATGSEEEKKKAAAAKPYTQTQITQMLDKLVKSYDCNLVESTTCWLFERNEIEGKKKIILAPGEGVKGEGFAEVGEVWGVEMGVSLGSGKVKTLNNRATLHRRTTTNYGLKRPSSRATLSEIMKKFSFFPFSLRQLDDERGAKVGVMECVRGNVLRQYEVVGDKDNEPVGRLFTTVAITKNGMTRVSAPPPPDLSKFKTNKKIKDDELLKILEQPISKASTSKAKNKKKKKKPARKAAEEEDDDEESSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1M1</accession>
    <name>A0A6A6P1M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Got1-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_285184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1M1"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000137">
        <property type="term" value="C:Golgi cis cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="139" mass="15002" checksum="64EC0A33477B218A" modified="2020-06-17" version="1">MPSMWLSDTQKIGVAFCSGGGFFLLGGVMMFFDRAMLAMGNILFLLGLTLIIGPQKTLLFFARRQKLKGTAAFCAGILLILLRWPLTGFLVEAYGIFVLFGDFFATIAGFVANVPVVGPYVAKALETISGGRRNAELPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1M9</accession>
    <name>A0A6A6P1M9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1M9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="15358" checksum="082CAEC2ADA5A988" modified="2020-06-17" version="1">MSPFPLPPSSPLFELRWLPHGWAWFATDANVRRVLQRRKGRGGSARGSGPVAESGAPTPPYLCRWREMPTGFGGLWSVVGCPPLVVVCVDTRALGFLFVSFRLRPPTPPFRRLFVACPFLHLGGFFFFFFCPLFGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P267</accession>
    <name>A0A6A6P267_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P267"/>
    <dbReference type="OrthoDB" id="2122015at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007008">
        <property type="term" value="P:outer mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035195">
        <property type="entry name" value="Emr1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17237">
        <property type="entry name" value="Emr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="8927" checksum="0AE23B7135B05CF8" modified="2020-06-17" version="1">MFRVSTYAYGASNKASIEKFPVAIMPSNLPNLRRLFVEARTEAEESAYSRNAFYNLGIFLSSIAIFSLVAQRMTPTSSGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2G8</accession>
    <name>A0A6A6P2G8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_319493</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2G8"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="10"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="506"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="571"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="660" mass="70409" checksum="04713557BDBF98F6" modified="2020-06-17" version="1">MTKRKLPVQQLFILAVCRFAEPIALTSLFPYLPEMIESFNVPKNEIAKWAGVTSALFSLSQCATAIAWGRASDAFGRKPVILLGLFNTMITGLIFGFSTSLPMAIVARALSGAGNGNVGIIRTMVAELCPWKELQPRAFSIMPLVYNIGSVFGPTLGGALSNPYNQDPTGPKGKRLLERFPYALPNIVSACIFIFGITVGILYLRETLESRKHRLDYGVMVGEKISSVTDRHISNIIHAIRGTPSSERQPLLKTNGTHAAQHNGIDEETPKKGHHHHHKYPPKFSEVLTKQSCINLVVYTILAMHSIGYDQLIPVFMHHPAQDQSDPSVTLPFKFAGGFGIGPRRIGLMFTLYGVATMLLQIFVFPPVARIFGVLRCLHACFITFPIVFIATPFTALIPSATGKQIALMCIMLVKGTCSTFSFPCSTILLTNSAKSVRILGTLNGIATSVSAIGRAAGPAVGGAAFSLGAKRGFVIAPFWIFAAIAILGLVPAFFLVEGEGFGDDADDALEPDADAPGDADDDEDDEESSFGSSGEDEDGLVEARRRAFASAARSDAGSESEYGEPAPLLSRTSTVSSAAAVSMTESEDEAGGSASGAFGRMPSYRRGSAAGASPHHHYQRIRRRSSAPIGMGRGFRRLSSNLGQSMSGLGPGGGSFGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2T4</accession>
    <name>A0A6A6P2T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_302199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2T4"/>
    <dbReference type="OrthoDB" id="25503at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="41679" checksum="4550DAF130F65011" modified="2020-06-17" version="1">MAEQYQPPPGPPPGHRSQYQSSSEFAPPPGPPPGHSGHHLHQQQQTPEIYAPPPGPPPSHRQQQEETYAPPPGPPPSHAQQTYAPPPGPPPSRQPASSPSQPYHDWQSIPDPADLPPPPSLTHHASPTGNASLAAADAAHAWTASHPLWEPRALAPEQREAMQAGALVLSKPREYVGDVLQKGRGHWFCRTWRKCPEACLLSTLPLYAAAHDSPLRSGRERTVYFELQVLGVGGLDDAEAGIAIGFVAPPYPTWRLPGWERASLGVHGDDGRRYVNDTFGGIDFTAPFRPGQRVGIGMTFAAPPPAYSESGKGVRMMEINVFFTRDGRREGGWDLHEELDERVLEGTMGLEGECDLLAAIGVFGGVDFEVFFSEDDWWYKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P303</accession>
    <name>A0A6A6P303_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc-ribbon 15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_341874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P303"/>
    <dbReference type="OrthoDB" id="5545479at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139:SF1">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="12076" checksum="24C9038548AD92F0" modified="2020-06-17" version="1">MFFFFTCGTHTFTSRLKGYEHVTTQCQNCGNFTANCYKRWEWFTFCFIPIIPFSLKPYHEVGCHVCNFFQDMKYRPDVQAQGGGGQQIPMQGYGGQQGSQPQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P331</accession>
    <name>A0A6A6P331_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P331"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="279" mass="31328" checksum="6FFE4BD8ACEB725E" modified="2020-06-17" version="1">MSPVLRRASETDKPDAPTPEPSKNDITIGGVIAISISILVILHVILFWAMYFRSKQLQRRKEQGKRPDVENQDTDPRLRPFISTSKQKLRNKFGDKRSRPLDIGKPMPTLQSPPRARAASADSVSLDKQGIGVEEIRLADVQAPGIPAPQPSRQARHESDRLDVPIVLDRGGPSELTYSYRNRYEQALERHGSNGSSRRRDHAGNIADSQSKFRSGSGDAEVPATFHDRPAELTSPGDHTYGSLGTISCRRYDYEQRHLSSPDLWRSLSQKRKDKTWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3T7</accession>
    <name>A0A6A6P3T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_370838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3T7"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="10"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="335" mass="36749" checksum="B22DB4268ECD5F83" modified="2020-06-17" version="1">MMYTFTVFKGSKDGTIIKSTTTKPDLTGDQVYLRITASGICGTDLHVQKADMVLGHEGTGVVEEIGPQVKHLKKGDRIGFGYQHDSCGSCQSCLSGRETFCDQRVWYSEADYDQGSLASHAVWREAFLFKLPAALPDVYAAPLMCAGGTVFNALRMYDIQPTQRVGVVGVGGLGHLAIQFAAKMGCEVIVFSGTDSKKEEAMELGADEFHAVKGKKTLDIGRKLDCLVVTTSNHPDWNLYLQVMNHGSTIFPLYVSEEPLVLPSLKFLQSAIRIQGSVIAARYMHNEMLEFASHHKIHPVTETFPMTVDGITEAMKKLSEGKMRYRAVAFPEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4C9</accession>
    <name>A0A6A6P4C9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_378398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4C9"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="105"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21539" checksum="17AB5A18692581A5" modified="2020-06-17" version="1">MLSCVLLLSDSSTMISGSADNTLRTWDADSGAHKHTFQGHTDNDLGSGQCLQTLQDHPNYVSIFGLNKDVATQFVNRDTDLLMSSAADGTIRTWSWHDGSILRVLEAHTGAVRGLVWVGKDRFVSGGIDGKLCLWNYGEGQPSSELRERMEAVWHLMGGQCKLATASKVEVGKHLVEIWDLCEFPRSEAEGLYLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4S3</accession>
    <name>A0A6A6P4S3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371263</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60955at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061700">
        <property type="term" value="C:GATOR2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="362"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="456"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="214"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="803"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="940"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="990"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1422"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="643"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="863"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="994"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1018"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1104"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1114"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1150"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1616" mass="173142" checksum="95823B4139DA34E1" modified="2020-06-17" version="1">MVLRAQEDGATDGGGGGGGGGRRGAVRARGGVSLARFLPPSSLFSPPSLPSCLASRGAESPPLPASSRAQLGRLDAGPRARPHHVSSGPADVVLAVVLVLLVLPPPPSSFAVVRCRVAGARDATAQPVLHHQRLKPTGRPPTVVVVVVFVVVAAAMAADHPRRVSTTPAATAAAAAAAASAVSSSSIPPAPPLPPQRENKNPFRRLFAGQTFANSVGQRPPSAQATRPDVAGAKPAAPKSSGIAPLSYRSQDATHRTGLEISALDINAERTHAILAGREILKTIHIADTKCAEVINLRAAIIQYASHNAPGTGLPARHRETLDIHDVKWSHSNYSSYIATAATNGKVVLYDLNRAGVELARLHEHNRQVHSLAFSPFSGNLLLSGSQDGTVRLWDLRDLRRDVRACPSKERFAGQSEGVRTVKWSPTDVFEFGFGTDNGVVQKWDFRSVRAPKLKINAHDKTCNALDWHPDGKHVMSASSDKTVRVWDFGSEHRRQRARWIIRAPYPVFNARWRPACWAGAGREEGAWQCTQIAAAYDREHPAVHVWDFRRPFLPFRMVARYASAPNDMLWHSRDLLWTVGREGMFTQTDVHFAPKLVDRRNMQAFALSPTGEVGAFIQRRPRRRGAHLSFQIDEPPSYAGDKGLKRLNPDKHSLSRSSADDSLDDSFLSSSWRRHHGRTASNRSAKSLSSTPPLYEGPARVRLFSESIDSDVEAFKPNQIALRGILLGTIDAPVFSYLAQKYKPTPFKGLPSVDGYLDVQKAFERNALLAQEASAYRLSQSWKMVGMALARVIRQRAAEHRKRRLDGEISPPQLEVKPEAPAVGEEARKPVNRVVRNLQAPHKGPGIIESSSNVPTPLARPQLSSTALRASVDGSSLPNPDHDDLSLGPSLVNAPPDGESASQSQDLLESLRPQYSGTRWYNSETDLSERRAMLTNWRAPPREPLSLENGNNGDGQGVSINIPPTLNRHYSDDSFAMFSASTDSRGISMPGSFMSSRSNMQDMAQSRGFESHYDSSLADSGSLHSGTPSPQLSRHPSHRAPQRQSPGLPDLFEEVAESRPLSGNAPEPRPIPSPDGGAGFDSNAQPNAQDLDNLGRNVRLLRGSTSTRSDLVSSKASTSDVSSSRMETMEASGTIVPENGYDDQQSPRDVPPPPPSPPPPITPHPERASAPAVIEANSQSIADPEHEPFALADFLSRDPSVNTEVGSPFTVSTLIKQLLAFHTITLSDAQSSSHFILLSTPLLPPTHRVPSREISGLLAAYTEHFAALSLPISPSLGTALSRLAATGIHPLQAEAILSTYHTQLLSLSLFNSAANLRRLCYPAFPAVYEGALKDVEVGLLCRTCKNPINNPRGKMRCENCQASQAPCPVCWMPQSPFPPRQRKEKLRRGIASGSAWKDGITTPVDIAASTSGLLAGDIERARHRQQSAAPATAPLEDSEGSAMASPPPSQHPTLWSWCPLCGHGGHASCLSVWFSNPSYGCGGACPTAGCLCDCVRGPRRDERIAAMEARRAEKERAKPVRLGDDRRAGESKAVGAVRGALQSGVRSGVAGVGGAGGGGQASGGGGASGGGGIGVSALGRSDTIATATGLGEGRRVRVVEPGDEAAGFGGYARKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4S4</accession>
    <name>A0A6A6P4S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein-vacuolar targeting protein Atg18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_283211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4S4"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="446" mass="46535" checksum="FF90FF13B60B2542" modified="2020-06-17" version="1">MNFVTFNQDYSHLGVGTTRGYRIYSTDPFSKTFQSHEGDITMLEMLFSTSLVALVKSPRLLRIENTKRRTTICELTFPTTVLAVKMNRKRLVMVLEVLIFVYDISNMTLLQTISTSPNPLGICALSPSSDNNYLAYPHPQRNAASNAAASSFAPPSHAPPGAAGARAAAAAAAPSSGEVMLHDLSKLEAVNVVEAHQTPLSCVALNSDGTLLATASEKGTIVRVFSVPDAQKLFQFRRGSIPARIYSMSFNATGSLLCVSSATETVHIFRLAANGHPATPTTPSAAGAASSSNLYPSGASNADASTTSLASAGGGPASPTLPPEGERLRQNPTFASMLRRTSQSVGKSFAATVGGYLPAAVSEMWEPARDFAWVKVPRGAAAAAAAAARPPGSPRGNGSGGGSLKTVVALSGSGPQVMVVTSEGNFFVFNVDLERGGEGTLVSQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5V0</accession>
    <name>A0A6A6P5V0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_384618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5V0"/>
    <dbReference type="OrthoDB" id="4095816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF2">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="670"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="756"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="851"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="867"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="908"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="967" mass="102541" checksum="29D33718D4BF1172" modified="2020-06-17" version="1">MSYNRQKNGSQPMLGATFIPGGFDDYYMPAQAPEVVSPAPQSSRIMAHCEVIARRSYRIMADMPENMQEGVARLELEADTGRRDTIPPQTPAKDNTYSSQRQNSFSQAPQNNPYENPPPQHLSNASRYSSYGSSTADTPAQSRTYQQIAQAPDFPHFSPFPKLAHRGPNVPESDDEREAVLENARTPVLNSNDPEMQLAWAQDALTYVDAAMLYEQRISETQPPRPGTPQVEHQLRVDAMNIVQFLADQHHPKAEFMRGMWLEFGKFGLRIDKREAFRCYSRAADKGYARAEYRIGMQYEQSNDPVKALQHYKRGSDAGDSASNYRLGMMTLMGQHGQPQDFGRGIQLIRQAAVNADENAPQGAYVLGMLQARELPQINVPEIFLPFDERAARQNIEKAAFLGFAKAQLKMGAAYELCELGCEFSPALSLHYNALAARQGEAEAEMAISKWFLCGYEGVFQKNEELAFVYAQRAAHAGLATAEFAMGYFYEIGMFVAVDADKALEWYERAARNGNKDAGSRIEGISKQRLLSKKDHESVAINRIRSQYGSKRGGRPDRFKQGAAGGAPALPTITDTPAPEPPAAQTPKPTSPTGPGGIRAPSRNATTTPYPLEDQGPSLTKLPSAGPDRGSSTTPYPLDDRPPPVAGRRPTGGTPGPGPTAGFLNPDLVRPASAAPPATARPTSAFGISPHLLAQQQQQRQGGPIDRPYTSVGDIHGGGRGGPGPPPLRVDVKMDEQQQQQQHARRGGRLQKQQSHPHSAAPMSAGAAPPNREPKLPDIGFAAPLDNKPPPLDPHAYPEGGGPAAAAAAAAAAASGSGKPLPTPATGRDALPSQQKQAAQQGRPQSARPHSPAQRPGSRASSAGRPGSAGGGRPAAAGAGGSPGLKAEGGVAVPGRKPVDGGAALAGAGAGAGGKTQGGGGGKVQPGGAGGAGMPPGKGPQTFDAMGIPQAKRDSECVSAFFSISRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P629</accession>
    <name>A0A6A6P629_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_340232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P629"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="240" mass="27072" checksum="BE0F485450DB1344" modified="2020-06-17" version="1" fragment="single">MANGGGNDGFTWHDADYKWTTQTVACGASQFPNLFGPHRFSYDTYKEACTVSRALLWIWIAHAGLISILVLLSTNPNFGRCRLRLQFAASIFGKCWRLPSEKIRRVFKTVLRSAKPRTDEEAAETSRQTDEEAPEGEHQADEEAFERRRQAAEGLAEEGWADEEAIEDDPEEERRADEQVVGMEDMGRGRQGQAHDPGGKPHSKRKHTVKGALPTISEEDRESGHGKDTRRNCKTSQRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P671</accession>
    <name>A0A6A6P671_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_338418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P671"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="299"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="411"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="542"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="412"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="573"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="592" mass="62258" checksum="B00EF40E76F42A52" modified="2020-06-17" version="1">MAHRQGDPPERHGSPPTALPAVNTGAGAAPSSMSSSWSSLQGGQGTGHRSPKDSLSRTPSSPIVGHRASFADNLRGMPGPGSPRGHRPASLTQQALQELLNNPPVARTGPATFDTELSGRDWRTVKVGEVTDPNEVRWAEMETSVEDATNTLIGSGAPNVVLLRENSSTTAAIGTFDYNDLNAYLLLVVGLAQPDASHIQSFNELARKGREGKPIPLKEVKDLGRKEPLIMLPHTANLTKAVEVFGSGIHRIIIVKEHTSSVIGILTQLRLVRFFWENGRAFPSIEMLYEQSLKDLRLGSKSVIAINGDKPLSDALELMNNEGITSLPVLDAQANVIGNISHVDVRLLTKSTSLPLLRATCIHFISVILSERGIHDGKDSFPVFHVTPNSTLAHTIAKLVATKSHRMWVVDPPGGYHSPSPGSSGPSTPAVGPSSHQLLVPSSPSLPLSGPAASSGALDQNTIAPPPTLNIAPAATAFNPTPNRDPVSSSSSSNSGAAPTPPQATPPLSVSASALPGASISGRLSGVVSLTDILNLFARASGLSPHDPAETRRQRRRSSSSSLQGFGRRSVDSARSSQGDVSRSGSVRGRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6E1</accession>
    <name>A0A6A6P6E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_192731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6E1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16615" checksum="98B2BD2B408CFCB4" modified="2020-06-17" version="1">MHNWLWAAVGRKACAAGTTAARRKTRGSERRSAKRRTDMSRAGRAQSARTSSGGCPTWARRGPLGKQERETKQTQGCCTEALGGGRKETDRRPGWRGKGLVRGGMYVCTENLATLPNRRAEATHVRTSAIVRCLSSPICVGRSGFDTEGPPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6E2</accession>
    <name>A0A6A6P6E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lethal giant larvae like, C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_300054</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat L(2)GL family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6E2"/>
    <dbReference type="OrthoDB" id="19944at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045159">
        <property type="term" value="F:myosin II binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15873">
        <property type="entry name" value="R-SNARE_STXBP5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000848">
        <property type="entry name" value="SNARE-dependent exocytosis protein (Sro7), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013905">
        <property type="entry name" value="Lgl_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241">
        <property type="entry name" value="LETHAL 2 GIANT LARVAE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241:SF25">
        <property type="entry name" value="TOMOSYN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08596">
        <property type="entry name" value="Lgl_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Lethal giant larvae (Lgl)-like C-terminal" evidence="5">
        <location>
            <begin position="518"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="935"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="946"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1019" mass="108943" checksum="8E7516F398E106E4" modified="2020-06-17" version="1">MAHLLRGKQAGIQNDLSAGITSDLFAVDDLGRYGVGSQISQIAYDPVQSLLAVGTNDTQFGPGQIYIFGQKRVNAVLPLPKRASVKALQFCADKLLCLDSKHDLSIYSLETKKLLAGHSAPGIVTALHSDPTLDYALLGMQNGDVMAYDLDREAPAPFKIPNLWKEINPRARAVPVVTLQFHPRDIGSLLIGYMEGACIYSFKQNKAVKFFHYELPRGAPGGDSDPASMSMARSPKLTQAVWHPTGTFILTGHEDSSLVFWDPKDGRIVMARTLADTNVDRPEAGNATPGGTHGTFALKEPIFSIAWCANVDPDDTAILVAGGAPTTMPTKGLTLFELGRTPNYATSSWQVLSSHFESPRRQRILPTPPNAEVIDFCLIPRTSPHFAGAQDPIAIIALMSSGEIITLSFPSGHPISPTNQLHLSLTFVHPFIIAANLSTIERQKWLGMTEHRAHGPLILTGGKESSHPLKRFEGRNVAQTAHADGTVRLWDAGHADEIENEELLQVDVARAVGRCDGVEVTRMSLAGATGEFAAGLRSGELVVFRWNHNRNAGREPPRDADNAGPGQLTNVTGRADPSLHDGLLPFTLLDQQDGPCTALQLSDVGFVAAAFEGGSLVIIDLRGPAIIYTASVTDFIKENKRGSFRRSGGRHGDSASKPEWVTVLEFSVMTLDGDDYSSLLLHAGTNLGHLATFQLLPGQGGRYSARFAGAVALDHGDRVVSISTLSADDGGPARATQRAVAGLRDGSTHVNGVVLAVGASGARLFRAPGEKHKGASKTWDEALCDAAALTWVGGPAGMDAKGVALVGLFGDGFAKAFSLPGLKEIAKVKLDGSAAGGEGPALDVRRFADAVVTQTGDVLGWAGPSEMALVNVWGSGLNFVRSKDTLFNPDSLIPPRPTISNLQWISGTQYITPADMDLLIGGPDRPPSKRMIAQARAEEQQRRAAARAGGSSSSAPQDEGYWASMQRAINERTEKLGIVGDNMDRLQENSNSWADDVNKFVNKQKRGFVMGAMKSKFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6P5</accession>
    <name>A0A6A6P6P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_300207</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6P5"/>
    <dbReference type="OrthoDB" id="429533at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000005">
        <property type="entry name" value="Proteasome subunit beta type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="12">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="276" mass="29885" checksum="7E38E5211E742455" modified="2020-06-17" version="1">MVGFDFSNHDRNLALHAKGVPLPKATSTGTTIVGCIFDGGVVIAADTRATSGPIVADKNCEKLHYIAPQIWCAGAGTAADTEFTTALISSNLELHALSTGRKPRVVTCMTMLKQHLFRYQGYVGAYLVVAGCDPTGTHLFTVHAHGSTDKLPYVTMGSGSLAAMSVFESQWKPQLTRDEAVKLCADAIQSGIFNDLGSGSNVDVCVITNEKATLLRNYITPNVREEKLRDYRFPRGTTAVLNEKVIKREDLSKYVTVHEIGDEQPTTAETMDVDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Y0</accession>
    <name>A0A6A6P6Y0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_281425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Y0"/>
    <dbReference type="OrthoDB" id="5335351at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16625" checksum="DD4DD79047B704A7" modified="2020-06-17" version="1">MRPPPAPTGIEAHIRSSPPVGAARSDGSDGRGAGAANGQSEKGRGSTGEDPADPIEQADWEDLYDQFKEKMEEHYTNEVQLHEEFVALMKFFKSWSETGQSVEAERASKRLRRRMSYVEAAEDDLEGKRQHYIKVVRAFESALNLLNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L9</accession>
    <name>A0A6A6P7L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_413702</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the polysaccharide monooxygenase AA14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7L9"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054497">
        <property type="entry name" value="LPMO_AA14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22810">
        <property type="entry name" value="LPMO_AA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025483638" description="Proteophosphoglycan ppg4" evidence="13">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2459869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="29968" checksum="E65137645A1C753A" modified="2020-06-17" version="1">MRTLFIGGLSALIHSVSTNAHTAAYAKGMYCRGGPNGDNQNANDPVVPLYQLSMEDWWFQHDRGCDLAPPPEDEFLELPAGGSFEVELAHNQAFTTLSFDGEFTSEWPDGGDHPEDWHGPGSPPDCIQEDGALHVQNESMAAGTAFAISYHSELSEVTLENLAVFTVRLHTPWKRVTSYDVPAAMPACPLGGCTCAWLWVPDGCGEPNMYMQGFKCNVTGATATSPVAPARPPVYCEDDLSSCVQGAKQMIVWQQAEGDNIEPSQSKSPGYNPKGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U4</accession>
    <name>A0A6A6P7U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_337225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7U4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16206" checksum="1E20B6F68BB3A0CF" modified="2020-06-17" version="1">MARTWRVIWRSREPSVLKSGAAPEQVRSMRPWSREQKFADGNGWKQRGQTGEWCGLRRCCSVAAAAVVVAVEEQPGRESVCDGTRLRREERKDLAAGEGASICTLVGCVTSGDDVGQSSGRAGMSRGVTFSRISMRPVLAMFSSIPATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8B1</accession>
    <name>A0A6A6P8B1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_337270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8B1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="85"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="572" mass="61225" checksum="61B9BFAA7DF0E448" modified="2020-06-17" version="1">MAARRALSRNLPTLATRSSVPRVASFAARMVLPSSNSTAVRRLHATASQLSPATTTAASTATSYPTTHERIQSPADTQNFLDNKFVASQATQWIDLHDPATNNLVTRVPQSTDAELRAAVDSAQRAFKPWKETSLLHRQQVMFKFVALIRENWDRLAASITLEQGKTFADAKGDVLRGLQVAETACGITTQLTGEVLEVSKDMETRSYREPLGVTAAICPFNFPAMIPLWSIPLATVTGNTIVIKPSERDPGAMMILAELCEKAGFPPGVVNVVHGAAKTVDFILDEPLIKAVSFVGSNKAGEYIYSRASANGKRVQANLGAKNHAAVLPDCNKNHALNAIAGAAFGAAGQRCMALSTCVMVGETKEWVGEIADRAKQLSVNGGFEDGADLGPVISPQAKQRIEDLIASAEEEGATIVLDGRGYKPDKYPAGNWVGPTLIANVKPHMRCYKEEIFGPVLVCLNADTVDEAIDMINANEYGNGTAIFTRSGATAGRFQREVEAGQVGINVPIPVPLPMFSFTGNKKSVAGGGANTFYGKPGLNFYTQTKTVTSLWRSEDAVATKAKVNMPTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8G0</accession>
    <name>A0A6A6P8G0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_405604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8G0"/>
    <dbReference type="OrthoDB" id="5206740at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="501" mass="50944" checksum="1065BCC57CBB14DA" modified="2020-06-17" version="1">MMLAVAMPMRPSTSFAPPPSSHPPPPAPSTTQDHPPSQSHPPQPPAQPHEHRAALPPISTSPAPTTATTTTPSSSAACPATSIPPPTMTTSLAILPSSPIHSHPRRPKLSLDTTQVRPLTTFGKGATSLRLDTLSATSPTARNTLRNAYEEGDSASDPTTASNTLNNSSSSGGGSIARSPASAAPTPTSASTLSIGSAISTSSADEPADPALRIPYKLAHNVPSILSNSPLRGLPHGGGGTDSGCNSAVMAPTATRFGARAGAARVLFPPRKRVAFRSPLAEEIRTTRYTLAHSDIAAVEAAAAAAAAATAGSSDEESVASSSASSSSTVSLSSEGEDDNGSGSGSGIDSAKSTSATPRALPSLPLTVSLPPSSSSLALPPRPSTPPAPSSSSNSPPTSSSSPPPPAPPPAPAITSSPKRLHPSSPRPGEKRDSSDEDDSGDEAAGAYPQTPVAGRRKRRREWVWTLGPIRGPAQHQQEQQQEQEQQEEGKRGEAGEEEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9E9</accession>
    <name>A0A6A6P9E9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SUR7/PalI family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9E9"/>
    <dbReference type="OrthoDB" id="5419460at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032185">
        <property type="term" value="P:septin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36414">
        <property type="entry name" value="PROTEIN SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36414:SF1">
        <property type="entry name" value="PROTEIN SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="28637" checksum="6B14D5FD6CCA0308" modified="2020-06-17" version="1">MAARPILGLVALFLLAGGILLQFLVVLSGGINSFPENLIYFLQASTDDIVPQPRNPSRWTFFAVCGVGDDGHNVNCGDPVPALPFDPTHHTNFNTEDGVPGEFIDTHYYYNLSRFMFAFYIIALFCSCMTLLVSILAPLSRLGALVSGLGGMGALFFQILAASLMTAWTVKGRDAFRAADLDAKVGVYAMAFTWTSVACFALATALFCVAGATGRHREREPRPSGARGRFGGLFRKKSARSTHSRGSFLDSESQRRVIKDEYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9M0</accession>
    <name>A0A6A6P9M0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_335588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9M0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="18604" checksum="CDBEAA0C27FFB261" modified="2020-06-17" version="1">MVLVLLVLVLAMLVLLILLLAFFLLQAYPCPGTNRSLPLVLLAGVLLASCGVAQLGVGRRGRVQRRPRSRRRRRGRRVRRQLLVYGGRVLPAAGLGLGLRLGSPSGAGRGRGENAATSGAAAASWGHVHRLQRRAQPSGQARSREQQQALRANVRRRSIAEWARRGGLCVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9T7</accession>
    <name>A0A6A6P9T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial small ribosomal subunit Rsm22-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_336171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9T7"/>
    <dbReference type="OrthoDB" id="421327at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052571">
        <property type="entry name" value="Mt_RNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184:SF5">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="409"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="660"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="754"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="800"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="850" mass="92476" checksum="5B7113A5FD1C0420" modified="2020-06-17" version="1">MGSDAAERARGRRRERDLEAIARKARQEFGDGIPEGLLDEEEIAVYERLYGTPYIIEAGDEGEEGGVEEWAEGEAGEAEDSAEKYVLLKDGEGGELEEVEFAVSGEGGDAEMARARALAEHMAKNGDEEMAEALRELDAAERALKGKESGELDSDIEAYHEEDLEDLEDDPAYLSEGDEPYEEDTYDTGSVTRTHPLTAAGRFSTFPSTLSLPRTALLDPLTTMLSSAHTNPKHLADTAHRVFGGPALPHSTASLNKRQKGTGVAQQPVALAAGQPQMTDIEAAAYCAAVMPGTYAGLTSALVEVRRRLGAKWVEGLLEKEGGPTVLDAGAGGAGVVAWREVLRAEWERMHEDKELEGEEGSEDTSLRGPPPLGKATVLTGPAALRHRASRFLENTSFLPRLPEHVSPAETAASTAAAAAAAGNEAPTGTQDDASKEASNVKGQKAQPRKLYDVILAPHSLWPIQEDYLRKAHVQTLWSLLNPNGGVLILLEKGLPRGFEAIAGARKLLLDKHIAAPGEETDLAKVEEEARRTGTLADLKGPAKEVGMVVAPCTNHEACPMYKVHGPAIGRKDFCSFKQRYFRPGFLQRILGAGLPGEGRPSRNHEDVAFSYVAVRRGRDARRAKHDEVFGMGFEQGDKAADEAFEGFGKEEVQEVEEAVEAVRSETSAEDNENKPTPPPPSTPNPLALPRTIDRPIKRQGHVMIDVCTPAGKLERWTVPRSFGKQAYRDARKARWGDLWALGAKTRVPRNVRLGREQRRGELQGGASAAEKESRRKRKPKYNVVVDRESGRVSLGGGGKVHEARKDVKGSKKAERKARAERTEMEREFSGQGVGWGNAEKEYDELMRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9U3</accession>
    <name>A0A6A6P9U3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_384206</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9U3"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025505365" description="Mannan endo-1,6-alpha-mannosidase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="406"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="462" mass="50703" checksum="EEF2F961C1DB196E" modified="2020-06-17" version="1">MLMRAWSWLLVATASLLCPSTSAIELHIEDEASIRDVASTIAYGVMSYYTFNASGTDPNLLGSFPRPYYWWEAGAVWGGMVDYWAYTGDRTYVNTTMQALLAQVGPADNYMMPFRQAELGNDDQAFWGLAVLSALEYDFPSPPATSPQWLDLIEALWNTQASRWDMETCGGGLKWQIFSSNAGYNYKNAISNGCFFQMSARLARYTGNGTYSEWAERVWDWTRAIGLIDDNYYVYDGSDDTLNCSEINHLQWSYNAGVFLHGAAAMYNLTGASSEWEDRLTGLLEAASVFFSPFDNATNVMWEAACEAIGTCNTDQQSFKAYLARWLGKTAVLAAYTSSAISTLLRASAEGAAASCSGGRSGVECGSKWYTGGWDGMRGLGQQLAALEVVQSLLINRIRDAPDTEGNVTITYGPTQTPTLGVPTRTRDVETPGTSSGSRTTLLGIGTARYLSSFVINIIRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAR5</accession>
    <name>A0A6A6PAR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_334260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAR5"/>
    <dbReference type="OrthoDB" id="2449818at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.20:FF:000006">
        <property type="entry name" value="Ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000002">
        <property type="entry name" value="Ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.20:FF:000009">
        <property type="entry name" value="Ribosomal protein L10a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_uL1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="24378" checksum="946BF4F6B9D3FC1C" modified="2020-06-17" version="1">MSKITVAGVRTNVQQLLDYSQNTKKRNFLETVELQIGLKNYDPQRDKRFSGTVKLPRIPRPGMSICILGDQHDIDRAKHHGFDAMSLDDLKKLNKNKKLIKKLARKYDAFVASDSLIRQIPRLLGPGLSKAGKFPTPVSHAEDLNNKVNEVKSTIKFQLKKVLCMGVAVGNVDMTEDELVSNVMMAINYLVSLLKKGWQNVGSLTIKATMSPPKRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAS9</accession>
    <name>A0A6A6PAS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_138188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAS9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="125" mass="14252" checksum="BE3555C9646EAED4" modified="2020-06-17" version="1">MEISVDSRDPIVPPMVFIYNDSTPASLRLKTYNRKDRNAVVEQFFGEIRRLGSADIRVQIHWVLGHIGMSRNYLVDKVARMAYRRAIESRAEAGARQVAQATSRAHLVWSYIESNTAAYNCFVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBF2</accession>
    <name>A0A6A6PBF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_360457</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBF2"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.10:FF:000002">
        <property type="entry name" value="Guanylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000776">
        <property type="entry name" value="Guanylate kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.10">
        <property type="entry name" value="Guanylate Kinase phosphate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="15"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="205" mass="22404" checksum="87AE551E821819C1" modified="2020-06-17" version="1">MPTAEPSADAALSARRPIVISGPSGAGKSTILKRLFGEFPDKFGFSVSHTTRAPRPGEQDGREYNFVAKEAFLTLKDAGGFVETAQFGGNYYGTSVAAVEKVAKQGRICILDIEMEGVKQIARLPHLRARFLFLSPPSVEELERRLRSRATDSEDAITKRLAQADVEMAFAKSGEAPHEKIVVNDDLEKAYAEVRTFILEGEAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBT0</accession>
    <name>A0A6A6PBT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_368566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBT0"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025376147" description="Large ribosomal subunit protein bL32m" evidence="8">
        <location>
            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="141" mass="15185" checksum="9EA33A926FE37AE0" modified="2020-06-17" version="1">MALVRASAAFRLLLSSPPTTTAAAAPALSVPLHLPRLLPSWPRPSSIQPALAVSAPPSVISLPGLLADLWDSVLRAVPKKKTSHMKKRHRQYAGKALKDLTELNKCSGCGRVKRAHVLCPYCVASIKDFWKTGSKPKESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBX1</accession>
    <name>A0A6A6PBX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_331877</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBX1"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="39496" checksum="4A2FC110AAD45F91" modified="2020-06-17" version="1">MPTANCLHYATQCFEGMKLYRSGADGRLRLFRPARNAARMRMSCSRIALPDFEPDALEALIKKLCAVDGGRWLPKERGDGFLYIRPAMIGSDPALGVNKPKEALLYVILCVFPALDVPGVLATGAPQAAAPPPSQQANGEGNASLTANGVALPMRPRGRGMRLLASPESEIRAWPGGFGFAKLGANYGPTLEATGAARVSGYDQVLWLFGDAAEVTEAGAANFFVVWRGKESGRLELVTAPLDSRIILEGVTRASVLDLARERLTVKENVAGLEPVDVVERTLTIHEILDAYTEGRLIEAFAAGTAFFIAPVGEIHFRGTDIEVPLAEGNSGSYAKNIKDWLKDIMWGRVEHEWGVVVPDEGVPGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC15</accession>
    <name>A0A6A6PC15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_376415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC15"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="146" mass="15433" checksum="7C8BB4691499BD5A" modified="2020-06-17" version="1">MGSPHVSSIRPPSSSITTTTTTATELSRDPYAQRVKCLEDHASSLTGSKIADKIRKLQLALAWADKEEGRKREARLLSREGGLSRKGNPYANPVVDVNSAASAGGCSPAATTISNHSARRARSALLFGLGAGINDDNNNSGQEQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC35</accession>
    <name>A0A6A6PC35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_331903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC35"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="97" mass="10903" checksum="B6865B1DFC489B2C" modified="2020-06-17" version="1">MRDVVVPLRGTTVRERMTNRYLPSPGARAGMSQSLLATTDRYSNYHEALGYQTSRWIVSHALTVMSGARPRVVKSQLPRSHYWAPASLSPRSFPSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC46</accession>
    <name>A0A6A6PC46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_331789</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC46"/>
    <dbReference type="OrthoDB" id="10251741at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="17444" checksum="36B2F731955B7C55" modified="2020-06-17" version="1">MSIDVSLDGRFTASGHENGGVYIFNNETGRMHHSLQGLQSPVRAVRFSPGGTLLAATGDARIIALYDVASGEQVAALTGHSAWILSLDFNSSGEYLLSGAHDGKAKVWSVQTRACVATHSETDQPLWAVRWLPKAAGAAGAGLAKAEMFAVAGKTGGIEVYREASGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCD8</accession>
    <name>A0A6A6PCD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Leucine rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_278651</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCD8"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000273">
        <property type="entry name" value="Leucine Rich Repeat domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="568"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="808"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="376"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="619"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="679"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="707"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="841" mass="91244" checksum="CA8B75D899B4ACCF" modified="2020-06-17" version="1">MDTEDGQAFIKNLAYFVRTHEKALANALQLQRESSKHGSTTGGAASPTTSQTVTSSSSSSNTFAAALSLPYLNFTSHTLKPAKLTLTPHHLFYLLSRFEELGIHVGHMNVRLENIHSDTSPTNYVSFLSQAQRRKNRSSDRDSIHSVSSIRSVMSGMTTLWSNLGLTSSASKTEKQKAIIQEELKYLYSAFTKVPCLRLAPDHKARLIAGYEEFPFDTAVPLFAFKNLSALEIYDVDFRQFYGWDRLAEQLRSLTVKRANVDDLADLLVNIVLDDMDRRRRRSAKVSSSPTPPMAASSSKPKQVDITKSSSVPDSPASGTGHESGSPKSVPMARSGSDETKNGSRARPRSNSPSRPTSARHHASYSHGSRSAMTQGVRRSSGSSTSSVRSATPRNSSSNLLSLGYVPSTKWRFLRHLSLADNGLTAITAAALSPLTNTLQSLDLSSNLFTEIPDTLSNLISLRALNMSNCMIESLHSLTRNPLPAITTLNLRANRMVSLAGIERLLSLERLDLRDNKLRDPTELARLTCIPNLREIYVNRNSFTRTHSNYRVTIFNLFRKTPGYTEDVTIDSTGPTYSERKQLVDRVPEAPNVPVVKPPPEEDVFVSPPAQSAPSPPAKETRNSKRVDEEVQPPRIVSLPNPRSRSDYAVTSQRRRKGAKHRVVEFSSPSHARSPASTPVANAPPKSPPSAVAAGPPPPIVGAHATSVDSTYGSSPDATPTRKPAQAALPGGGVPPASPPQLTKNNQEREALPHIDTAAISPLRADSSELHVGVNGELYKKKIEALRNDFGNGWLTALGDDTWDGAGGGGGGHHQDLNALRPAVPPRTTSQTIVSGGRTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCD9</accession>
    <name>A0A6A6PCD9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCD9"/>
    <dbReference type="OrthoDB" id="10256055at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41677:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41677">
        <property type="entry name" value="YALI0B19030P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37249" checksum="CA32E65F6D707B14" modified="2020-06-17" version="1">MAPSILVQPPVEPSTTTAAPAPPANDDYYLSNAYRGPSKVKFDPSIHLSFTPWQGRYTLSDLGLPASAGANDFGTTEPFQLASPAAVLELRRELLQESTLKKRLHWWHRSPACLRGYTAAEAPFIHQFWTSPEVIEIVSEAAGIQLEVCLPYEIGHTNVQLGPGGRAGLKDLPVTPAPVPPGWQERRSDYDDVNVDDWHVDSFPYTCVLMLSNTDRMVGGETALRLPGGEIRKLRGPTTGSCVMMQGRHMPHAALRAWNTGERITMTCPYRPKHPALRDDTEITNSLQLSYLNELFGQFALERFRVLQKKSEYMIGELENGKKEAWHWIRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCJ9</accession>
    <name>A0A6A6PCJ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_92309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCJ9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="209" mass="22443" checksum="411B64BD4003F004" modified="2020-06-17" version="1">MRPSVWQTLISLQSSILLASQRRAWTLAFGTHLGRTGPFAAAALVPPSYTIAAPFAWSGRISRSTRRSFPASLWLVAGGRLMTGRLMAERGVKAADEERKITPRRKPSQTGAGMGGEVGGRDDGAGVSPAVYESPRPRGRKVWSGLAAVHDLRPRAAAASPVRSRGEVVPKRAKRKPSPTSGQREFSPLGLSLLLLEYTQIHSANTPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCP0</accession>
    <name>A0A6A6PCP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CRM1 C terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_91569</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCP0"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000490">
        <property type="entry name" value="CRM1p Major karyopherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1041"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1041"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1074" mass="123196" checksum="659CDCEDFFF75422" modified="2020-06-17" version="1">MMPTIEELDNTVRTFYEGRGNDQKLAQASLNQFRENPDAWLLVDKILQEAQYEQTKYLGLQVLDNVIMTRWKVLPRDQCQGIRNFVVNFIIQLSNSEETMKANRTLLNKLNLVLVSVLKQEWPHNWPTFINEIITSCHSSLPICENNMAILRLLSEEVFDYSADQMTSTKTKELKQSMCDEFTSIYQLCSEVLRTATDSSLIRATLETLLRFLNWIPLGYIFESPPSGISLIENLRSRFLEMPEFRNITLKCLTEIAGLHTEAAYNEKLVSMYTETLTSVSRIIPLSLDLKSTYAQSNSRDQEFVQNLALFLTNFFCMHLSLVENLPNRDYLTHGHFYLIRISQIDDREIFKICLEYWTKLVSELYDEMQQLPIGDMNPLVGLGGLANGAGMRDPSMLPNYPLRKNKYADVLSNLRVVMVEKMVRPEEVLIVENDEGEIVREFVKESDTIQLYKSTRECLVFLTHLDVQDTENILTDKLARQVDGSEWSWSNCNTLCWAIGSISGAMNEETEKRFLVTVIKDLLGLTEMKRGKDNKAVVASNIMYIVGQYPRFLKAHWKFLKTVVNKLFEFMHETHEGVQDMACDTFIKIANKCRRHFVAIQPGESEAFIDEIVRNLRKITCDLSPQQIHTFYEACGYMISAQGQKNIQERLIQELMALPNSAWDQIISQANADPSILHDGETIKVIGNIMKTNVAACSSVGTYFYPQIGRIYLDMLTMYRASSNLIDEAVQRDGNIATKTPKVRGLRTIKKEILKLINTYVEKADDLEMIHNNLVPGLLEAVLLDYKRNVPDAREAEVLNLMTTIINRLHSMMEDQIMNILDNVFECTLEMINKDFSEYPEHRVEFFKLLRTINLRCFGALLQLDGRSFKFVIDSCMWASKHDNREVESAGLNMCIELMSNMADTDQQTCNVFFQTFYTSILQDVFFVLTDSDHKAGFKSQSLLLAKMFWLVDSGKIQGPIYAPDMAPAGTSNKEFLRNFVANLLGNAFPNLQQAQIMNFIDSLFASNNDLGKFKLVLRDFLISLKEFSSGDNQELFAEEREQAATKAREEERERAMKVGGLLKPSEIDDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD89</accession>
    <name>A0A6A6PD89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_367970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD89"/>
    <dbReference type="OrthoDB" id="5412996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="69" mass="8204" checksum="FFA1E27B00037675" modified="2020-06-17" version="1">MREPRLTKHFWSNYVAQKPFDIDDLFGTDLKEDSIGVESLDEKHDLGEDFVFLLSMNEARDEKREEIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEU4</accession>
    <name>A0A6A6PEU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycolate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_313310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEU4"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF114">
        <property type="entry name" value="ARYL-ALCOHOL OXIDASE VANILLYL-ALCOHOL OXIDASE (AFU_ORTHOLOGUE AFUA_3G09500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="113"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="617" mass="68579" checksum="E696E411456306F9" modified="2020-06-17" version="1">MSGPLQHKPTDFSFAVPPTLEQKHSGVPSRLMTDAREMKQKLMSTAKPANPSGVHERPRLPPGISREDFNRAIAELKGSLGENYVELNDKPLVDGWYMEHPNTHDAFHIVGQDELVASAVVYPGSTPDVQTIVRWANKHEIPIYPISMGRNVGYGGAAPRVPGSVVIDLGRRMNKIVNIDAENASCLLQPGVSYYRLYEEVKKRKLPLWIDCPDLGGGSVLGNACDRGVGYTPYGDHFGMHCGMEIVLPTGELLRTGMGAMPGPNGADNPTWQSFQNAYGPTSDGIFSQSNFGIVVQMGFWMMPETSHQSYMITFPREDDFPKIVDIIRPLAQQRVLGNVPQLRHVIQELSVTGFSKEHWFPGGGTNERRIPRDVIRKHASKMPCGDCSWVFYGTQYGDPAAIKTQLDIIKKAFSAIPGSRMLLPEDVPPEHYLHARVKVCSGEPVLRELDWLNWVPNAAHLDFSPISPTRGRDAEIVHGIVAKLYKKWGFDLFPTLCVAGREMHYIANILYDRASLDEKRRAAGLMRELIAEAAKEGYGEYRTHLLFADQVAGTYNWGNNALMRFNETLKDALDPNGILAPGRNGIWPKRFRGKGWEIMGDEVEKAQSGGAITPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEV9</accession>
    <name>A0A6A6PEV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GTP-binding protein Sey1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEY1</name>
        <name evidence="12" type="ORF">BDY21DRAFT_277490</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Enriched in the cortical ER. Concentrated in punctae along the ER tubules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEV9"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046758">
        <property type="entry name" value="Sey1/RHD3-like_3HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20428">
        <property type="entry name" value="Sey1_3HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="1"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="789"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="813"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="11">
        <location>
            <begin position="74"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="841"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="841"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2462362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="890" mass="99648" checksum="0A077A09CAC14308" modified="2020-06-17" version="1">MTTASPANRSGRRPSLKPNPTAPSIMMNGHFASVGDGPASREQYQHGIQVIDEDKNFNPNLSTYLNLESVIPAGFNYHLISVFGSQSTGKSTLLNFLFGTHFGVMSEQERRQTTKGIWMSKNKRAVANGAMADNILVMDVEGTDGRERGEDQDFERKAALFALATSEVLIVNVWEHQVGLYQGANMGLLKTVFEVNLQLFLKDRKTTTRSLLFFVIRDHLATPLANLRATLLQDLSRIWSTLSKPQGLENSKIDDYFDFAFAALPHKLLQPEKFEVEVEKLGGRFREGYKGPRKVGLIEEESAPVFLPEYHRRIPADGFPHYAEGIWDQIVNNKDLDLPTQQELLAQFRCDEISREVMVSFDEAITPQEEKQAEGVRAGKPAVIPELGEVMNKARSDVVTNFEREASRYHKGVYTRKRAELETSVDLRLKALFQGQISAVHKSGVHDFSEAVSTAVKAGQKQGAASYDFAQIVESEKKKSLARFESQVQAAIVESAPWSSYQQELKLYQKELDTVSSRLRKDEMRRLANRVERWVRSRLGESVGLEFNRIGSGRSGSGAPADGEKPATEKDLWDRIWNVFTETVAQAEARFTERARSFDASPDEVEVGLWRLRRKSWVALKDQIAEEVMEGNLLLKLRENFEDKFRYDATGVPRIWRPTDDIEGIYTTSRESTLKLLPLLSRFKLSRTSAPPPLDAWIGSPPSSVSSADEEDLVAIGGVDEEEGKSLEEETTVLSDAKLQDYGVRFKKMADGVYVEAKRSAIGAVAQVPLYFYGLLLALGWNEIVTVLRNPVYFIFLVFLGVAAYVTYTLNLWGPMLRMANAASSQAVEIGKERLREFLESSDTGRQAISMSGHSEGGRSSYRDSDRINLDTLDSSGKKPAQGSTDDDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEW4</accession>
    <name>A0A6A6PEW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEW4"/>
    <dbReference type="OrthoDB" id="5395390at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="754" mass="84366" checksum="41A13B2FCFD6E77C" modified="2020-06-17" version="1">MSRRRAGIPLRSNLAGVSYRESSPEDDSGEIDYADESDFSEATAPSRGVSRAEQANNSSGPSKRRKTRAKATVSYHEPDSDDEDKDDDGDSDFGSDVENGSPETPKAKRARTLKKTNKRASPRKNVTPKKAKKSAATTPKRGRTMSGVPAKHRAKPALSSVQSDHVIPPWTSLPYEILLSIFTYAAYPMVDEATWASTRSASWLVKAATTCRAFAEPALTALYRCPPLALVGQAHQLLDVLSLPKETKFINYNVKVFSLDLEIRISLASSYAGRGRFTLESILPHVPQLSSVRIFDRNNFKTHVDVGIRHSNKPHWHYSNSILEALKANNVRLKRWVWDEAHIPRPQGAETLRAAHSSAPFQTLRSLHMSNFISIESLPGYLEYDLLAAKEEWSFDEEEEYIFRHVTALATAINALPNLSDLAFNSCNIVHAAFFTKLQRPLEGLTIMDCHYLTHWSLIPYLRNHGNQLKKLHLCHNDGIGISTFGLFHSLCQSLEDLKMDFSNVPGFRTPELDNNSLWMSPRWPSTLRDLELVHMRHWGARGTSADADDTHVVFLQSFIDAATALPTLRRLVIHMIIHIDWRERATFRDKWVHRLEHVFLRKRPDPDPALMSLKNFRLWKEAQVAAATAAKGKGRAAEEGEGRGANGKGRAAGKRARSRAESGAERRQLRPRGRAANDKSTTSNGEDESTEPGRDGRRRRSSSPALPVQGLCDVVDIRIDNMRLAATLFNEGDFLDSDNESDGSWDGTHTWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFA5</accession>
    <name>A0A6A6PFA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">L-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="15">1.1.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_383316</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:19909"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19910"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">In the C-terminal section; belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the N-terminal section; belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.3" evidence="15"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFA5"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004460">
        <property type="term" value="F:L-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000062">
        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000012">
        <property type="entry name" value="Mitochondrial cytochrome b2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF82">
        <property type="entry name" value="CYTOCHROME B2, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07200)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="18">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="19">
        <location>
            <begin position="103"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="272"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00061137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00061589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00066458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00068515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2462389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="511" mass="54520" checksum="5B5FA9C9B2C74D52" modified="2020-06-17" version="1">MGKVFDYGEVAQHNTRDSCWVILYGTVYDVTSFIDEHPGGANIILKLAGTDATEEYDPIHPPGTLEESLAPEAKLGAVDHSTLPKADKAPAQDASDTEQAPLPDVEDVLNLDEMEEVASKKVSRKAWAYYFSASDDLASKTFNNTVYRQILLRPRVFVDCTRCNTATALLQGRHRVGVPFFVAPAAMARLAHPDGEAGIARACARFGAAQLISNNASQTPEQIVAGAVPGQVFGWQLYVQNDRRKSEAMLARVNALDAVKFVVLTLDAPVPGKREHDEREARKVGAKPPAPSSVQGGGSTSTTTPEPATAAAPSNPDADAQQGRAEPQGAAVGKTLFAGTAADLTWEPTLAWLAEHTSLPIVLKGVQTHEDAYLVACHAPQVAAVVLSNHGGRALDTAPPALHTLLEIRKFCPEVLERVEVWVDGGVRRGTDVVKALALGAKAVGLGRAPLWGLGAGGTKGVERLFEILKAETETCMRLLGVERVDQLGLKHINARAVERDIYDATASTAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKY5</accession>
    <name>A0A6A6NKY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Rheb small monomeric GTPase RhbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_388681</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Lipid-anchor</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKY5"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04137">
        <property type="entry name" value="RheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2452316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="21040" checksum="F8B775A49A0311D2" modified="2020-06-17" version="1">MPSPPKQRKIAIVGSRSVGKSSLTVQYVDGHFVESYYPTIENTFSKVIRYKGQDYATEIIDTAGQDEYSILNSKHFIGIHGYMLVYSVASKQSFEMIRIIREKILNHLGTDWVPMVIVGNKTDLRPEQRQVKPEDGRAVADEFKCAWTEASAKYNENIAKAFDSMIAEIEKAQNPSEPTGGNKCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLW0</accession>
    <name>A0A6A6NLW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_358351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLW0"/>
    <dbReference type="OrthoDB" id="3742617at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="31742" checksum="38708C7B087BBF31" modified="2020-06-17" version="1">MPSANQFSLPDGRLMSYELSPKSDEYSPTVLLSNSLCASFTTWDHVVPVLHNRGFRVLRYDQPGHGSSSPPANPESTTFESIADDVYSLLSNLGITSLYAWIGVSMGAATGIVFVTRNPGVVKNLVICDTISCAPVVAGVENLFAPRVEIARREGNLDSIVEQTLARWFAEPWMEVNSAETERMRAAMRKTSVEGFAACCNALTLTSFDLRALTPKVGSSVDRAMLVVGERDANLPQSMAELRDQIRQGFVSAGKEGVNVELKIIKGAGHVPYVDGFDQFCEIVTEFLQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM18</accession>
    <name>A0A6A6NM18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_404703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM18"/>
    <dbReference type="OrthoDB" id="5430106at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22794">
        <property type="entry name" value="THAP DOMAIN PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22794:SF2">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="817"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="874"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="696"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="831"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="918"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="964"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="988"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1082" mass="110625" checksum="780604025A9867AB" modified="2020-06-17" version="1">MPSQEALQPRRSSSTMSTSAAAPVATGSPAANQHNPRHSTSSVASAESTRQQQQRQQPQPHQAAHHSPASNGNGGFIAGATPSSHPRSQPSTSPKEDRHPEKPRPHKPRQQHVVGGGHGRIGRNTSGKNLSRLNRASATALSQLNHDGGGGAGGAGGSPTSKQPHHRSSLSGTWTASQSSSPRPGLFKRNASAYAIPKHAPGHTSQTALRKNHSSGALAKGGSKTAMKQSAAAQARRAAKHGPAAPAAPAIAHHPTVRFDIGSDEDDPIGDPDADDGWTEDSASQSPMTTRDNTRRNSVVEEHGQAAHLLAPAGKSSPKAAREGLAEEEAPTSPSQSSSSRPTTSGSSGRHVRIQSPPTIGAIGTPYPDAGELEDTANAESTGSSYVNGSRKSSTASQLSSEQRQTSTSPPTPPVQQEQIHPQTYQSYPPSATSSRNHHHHHGIPDADAITSRLLQRRRAPPQMSSVSATVASDAHSPQSLSRGSTVVVEEAPSGASAGAAGTPGTTTGVSGTSASGSAGQELVSRFIVNGDDGSAVGSSGTPRESSFLPPRSRGGTDAQQRRRQQQQQQDREQAEQQLDKKKRNKSTPNMATATAAANADLDASGNDTAPSTKSHARTSSNPTPSATTPSTTIITPSSHAQHQPPAVANPALHPSRTQQKLWLQRASSSIEPARAIMPAPTPGGPGGTAPGAGQLGLAQHGQLQLQQHRGGGGVALQAGAPFAPGMAPHSHHMAGMGMGIGYGGLGPGGVGGPGSGGGGVVVGPAPAGMLAGPPGPGGSRDPRRIPRLLRQADQAAIEYRVVRRFRDPVAEAAGRVGEMRARRKGGAGAAEGPIEAGPPAARKRPASARKAGSTGHVSFAGGTTSAAGGSLAAAAAAAGPPRDGAAHPGIAPQQPPSAALPPAADRRRQKPPPPPSSSSSAGGAARAQRQHRHQRVSFELAPPPGAPSSVEDEDAQAAAGLGARIGGVGGGSGGVGLEGRRKGRGEAEEDEDEDEGGGLGLWRRARTESRESRSMRRDGDPLGPWTDHRLLRRNSAWAAPAVGVERAPRQSFVDLVGAHWCWRAAVPCSYARLSPFGLGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW3</accession>
    <name>A0A6A6NMW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_146643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW3"/>
    <dbReference type="OrthoDB" id="2687876at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="40593" checksum="0577B3B6E6114EFC" modified="2020-06-17" version="1">MASRSFSGFRSETEFDLREKDAAAIIWVAAFHCRDFDRAVIWFPPDVHRDVQPSISGSFARPSNAGLGSLDQLSLELLFEVCRQLDLLSLFKFRQVNLYARLVVNSLLEYKKTISYGLNPLCALLRTRLGSGVTLSDFYRVMRTKNCELCGHFGGFVFLPTWTRCCFDCLQQAPETRMETLDSIQKRLRLTPQEVLQIGSFQPLSGFYSMDESWHDPRFKLVSIQRAASVLQREATDEEQRQAQPRNSTFQYMASCALPFFDVGTGMIEHGISCAGCQLAVERIMNREERSRFTIPKYIVDYKGFLEHWEWYTTHKVFSHEGFLEHFKWCKEAQDLYTSSEKGTVEPAERPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMX7</accession>
    <name>A0A6A6NMX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Golgi apparatus membrane protein TVP23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_358491</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Golgi membrane protein involved in vesicular trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Golgi apparatus membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TVP23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMX7"/>
    <dbReference type="OrthoDB" id="2151161at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008564">
        <property type="entry name" value="TVP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019:SF7">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05832">
        <property type="entry name" value="DUF846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="21537" checksum="9B6AB2BCF55B86B7" modified="2020-06-17" version="1">MDNPRPGMLTWRLSSHPITLLCFLGFRIASLLVYLLGMYFTKNFVLIFIITILLLAVDFYYLKNIAGRRLVGLRWWNEVDPGTGDSHWVFESADPDTRSINETDRRFFWLALYAQPCLWVLLAIVAVVWLEFIWLSLVAIALVLTITNTLAFSRCDKFSHATNIASSAVYGSGLARNIAGGMFSRMFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNA5</accession>
    <name>A0A6A6NNA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_153369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNA5"/>
    <dbReference type="OrthoDB" id="2015992at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="27885" checksum="B8EFF65276957C08" modified="2020-06-17" version="1">MSASDMAAIQAAKRDLRRQIKSVLSGLGQHDIATQSAHAVRALLSLPEFAAARRLSIYLSMPSSEISTAELVSASLRLRKRVFVPCTYKCTAPPSRPSQPGSIMDMVEVTAADFEDGAVTLKPDRWGIPCVSTESLAARANEFGGVGLTEGVVPKDGGREGEEEAGLDVIVMPGLAFDREMGRVGHGKGFYDYFLSRMRTFVEESRGRKRMPFLVGLALNEQVLPPGQTVPTDPTDWRVDALVAGDGSVVRASDCDSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNL5</accession>
    <name>A0A6A6NNL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNL5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="19191" checksum="D2C8C8800D26EDBE" modified="2020-06-17" version="1" fragment="single">MASTRFLKGGPGGCMWKGLAIYAGVVGPALGVYFVDPGARVTSAMGGVAAAMRRGVARWVGRKRLLSARDWTRSACWNSALFLSCFSPLYQVYVWQRPSSRLKLKSVSGLALVSPVFTAYLIFAYKANPICEEVDPERSLGSTTTGFDNGRLESEDYRLSQLTHRGPKSGDHVHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNP4</accession>
    <name>A0A6A6NNP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_355751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNP4"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10039" checksum="762E858F265CF6AE" modified="2020-06-17" version="1">MVRQRAPSTTSTNSSVGVQTNQELGSMYDYLAKIILLGPSGCGKSCLLHRFVKNEWRVLTSQTIGVEFASKIVKVGSGARRKRIKLQVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP71</accession>
    <name>A0A6A6NP71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_355398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP71"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="54" mass="6173" checksum="EDECC7986413AD81" modified="2020-06-17" version="1">MMSLLTALVYVAYPTMLKLATPFFYLSNFQTCYLSLPPFTFLFQAASFIIHVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPY0</accession>
    <name>A0A6A6NPY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_355073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPY0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025669492" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9851" checksum="D57518B72C21ACD6" modified="2020-06-17" version="1">MVIFFFFLPFCFFRSWSSWVGSLFGRICMCLSVNGVFSQGEARREDGNRTMMDWVLFAVKSINNREQSRQSTPHRSHHGDHSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ46</accession>
    <name>A0A6A6NQ46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ46"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="285" mass="31550" checksum="2DDBF7D9E2221991" modified="2020-06-17" version="1" fragment="single">MRMRGRRSRRLVRVRCLRGWGIGGVTVAAARELVGVEHDALQGVGCVLWILEVVGARASGLQARALSVGWRNCGSVGDCVDVCRHSRGVRSIGYSSMAILSGSRGGLRSRTRKRAMFTLGRRQRIWRGSQRGRERAPLEDDNFLIVLIAIILFRRIGDGLLSLNIVRDALGTSIYTTNPLTSPCVLFAILTPTLVLIQIRHIEPPHIICRRAQLLGLDAQRAHHLHRLLAPLHQPRRPRRPEPTAWGSTLEARTAARTTLALGRMSAVRTAMDILALVGVEQSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ54</accession>
    <name>A0A6A6NQ54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_120636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ54"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000050">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="1"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="275"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="508"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="380"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="618" mass="67114" checksum="B1C8CCE40537D549" modified="2020-06-17" version="1">MNPNTQQTTLIPPAAGEVSSSGAHGKGRRPLDEKSFTFDHSFWSHNETDPHYATQEDIYHSFGVEFLDHNFEGYHTCIFAYGQTGSGKSYTMMGTPEQPGLIPRTCGELFDRINNHPEPNTTYNVYVSYFEVYNEHVRDLLVPRTSPPSYLKIRESPADGVYVQGLTDVQVKNYDDVARLMKAGDTNRTTASTKMNDTSSRSHAVFTIVLKQIAHDMDTDETVERTARMRLVDLAGSERAKATEAKGQRLVEGGKINQSLTTLGRVIAALADQAAAGGGGGSGTPTRPGTPRGGGGGGVSGSPRKHSAPAKVPYRDSVLTYLLKDSLGGNSKTAMVACIAPSDYDETLSTLRYADRAKRIRTRATVNRDALSAAQRDAQIAAMAETIRALQLNLNSATARNRERALSEQEAAANAVEDYQKQVVKMQRLMDEKRQLAERKIDLLARECDELRRENAKLRGEIEPVRRHLGLALGELKNPIVVPGTASPTKAATAVAGTNRQLAKWAGAKARGVDDAEDKENAGARGITGDNGAKDGGVFEDRGFHGDDDDSGLDEDDESGYEDSGNDEEALAIQRDAEELMKELGLWRKRHAEDVARFAEPGGRCGSGPLMELAAFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQB6</accession>
    <name>A0A6A6NQB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_366721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Cajal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMN family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQB6"/>
    <dbReference type="OrthoDB" id="79171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20446">
        <property type="entry name" value="Tudor_SpSPF30-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010304">
        <property type="entry name" value="SMN_Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06003">
        <property type="entry name" value="SMN_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="115"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="332" mass="35406" checksum="A8293C6E6B455A75" modified="2020-06-17" version="1">MEAELTELRPSLDEFLQQLEDVNNKLALDPGHGPSLELKAALEEGVAELEPLVKDLESKIAATKKPNSSSVAAPSPSPTVSLEQPPPPPPGARKPFSAPHTPATPNTPIQAGPPKYKVNDSVQARWKTGDRQFYPARITSITGSTSDPIYYVVFKGYGNTETLRSADIRPISGHKTQQNQTSANMGAEVDPTVAATASAGGAGMKRKAEEPLGASTAPGRGSSNVISAAASIDPALASAAKNKNNGDAVAMNKHANRAQKIPRKVKATKELEKSKSKWEEFRSKGPGKVKKDSMFRVDPSVNARVGFTGSGASARKDAHRSRHVYEQRKDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQG1</accession>
    <name>A0A6A6NQG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division control protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_292710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQG1"/>
    <dbReference type="OrthoDB" id="5357220at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012535">
        <property type="entry name" value="Cell_div_Cdc14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08045">
        <property type="entry name" value="CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="286" mass="31785" checksum="E5D2B4B3DFFA49EF" modified="2020-06-17" version="1">MEALLSLAFDNISSKDSSKIRKGLRQIDGLLAQICLSSKPSRSQLESQSPSKRRASAVPANRQASPPKRLRDLHGDPAFLEFFRLQEGFEWNVASRLVNCLERLMGMGNNGQSDLLILSTLDLLQGVLLLHPPSRTLFSREIHMNMLLDLLDSVNPPAIQSHAVLVLVTALLSVPRNTRVFEAADGLLAITSLFKSSGTVRSVKTRVVEFLYFYLMPEAPVQKGDSSKGGDRLKDMFSQEDEVDDEIMKYAKPTSEKTALLGRYLSNVEDLVQDLRENAPFGEIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR08</accession>
    <name>A0A6A6NR08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_354303</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR08"/>
    <dbReference type="OrthoDB" id="28092at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025526887" description="ER membrane protein complex subunit 1" evidence="12">
        <location>
            <begin position="21"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="912"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="14">
        <location>
            <begin position="20"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="713"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2454176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="941" mass="101989" checksum="7FEECAD9A63B45B7" modified="2020-06-17" version="1">MRLLRTLLALAVFILPPVLAIFVDEAFKIDYHYALLGQPQPSTTFFHPPFAASKASLIYTLTNKLVLGAVNPKDGAIVWRQLLQSPTNDSETLLRAGENQDVVVSGIDGQVAAWSGADGKLAWQSRFGSAQVKDLEIIEFEDGKAEDGVRDVIVLFGGDMPVVRRLDGRSGATMWEFEDSSGDTPFQVTVSSSKIYYISLYSPLLGSSKLKVTSLNPLNGQRVDQYTLASDTDVSSADSILFAGANSASPILAWTDKARKNLKVNIIGNKNIISLGIENTSAEEIEKIVLHAPQKINSLPHFLVHYQTAGAHWAEVYHTDLARATISKAYSLPSLSGHGSFAVSNVDANVLFTRITNDEVTVVSSASHGILGRWGVQGFDSLQAVHAVSEVVMKSGSASAVRCAVLRSNGEWAQLRNGEQSWSRPEYLSGVVAMTWADISRGESLAHELDIEAHENVLEAYIHRVKRHIGDLKHFPAWIQGIPDRVLASFLGKQDSNAPGKLQQDTFGFHKLVVLATENGYLTALDAGSQGKIAWSSEIIKLPSSTKWANVTLEVTSDGNILVSESGAVRPVHVSTLTGQIIHEEAALETSGKLEQDGKAVIMYDIIDGELQGFLLGKPGSAPLWSFAPHAGERFTSVIARPMIDPVASIGKVLGDRRVLYKYLNPNLVLVTGVTDSTNTARIYLLDSASGNILYVAQHDDVDTSRPIPSTITENWLAYSFTTLASPLNPSRGYVLAVAELFESPLPNDRGPLGARENVSALHPASGGEPAPKPHVIAQAFHIPAELSHLSVTRTRQGITSRQLLAVVPDLHAVVAVPRSAIDARRPVGRDPSADEAAEGLVKYHPVLEFDPKWFLTHSREVFGVQRVSAAPALVESTSLLFAWGTVDLWGSRVAPSFSFDVLGAQFNKMQMAMTVAALGVAVFVVGPMVRRKQINMHWQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR25</accession>
    <name>A0A6A6NR25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear distribution protein RO10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR25"/>
    <dbReference type="OrthoDB" id="5403729at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="23593" checksum="BFDD1EE0329BA115" modified="2020-06-17" version="1">MKDDLDSVALETLALLEWRLRRLEFILTGNEDYEEQEQKTKGTIVERLHALESTFASLASKSKIMSEVQTLQSRLPDLFQSAKPPLDAPSQPPASSFNPAQLLATVLASAPTFQSTASQLAALRDLSLPPTPVFASLASQQPRLAAAADRQLQQSKEISDLRKRSALAVMRWHEVMVLGQGRCWAEWDGRLKAAEREVRREEVRREKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRS4</accession>
    <name>A0A6A6NRS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRS4"/>
    <dbReference type="OrthoDB" id="5336565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="615" mass="68679" checksum="49634ED55CA1E04A" modified="2020-06-17" version="1">MLELQPSSSRKRPRSELPQLSQTSQPISKKQRLSHGESPPPPAFWDNLSKVWLTKRALRELDRRNIEAAPSRPPCSPHRPARRPKRNCQTAQYPGDYLSCCEPRILKDIKLFARHGGPDLSDLRNYPEPPHSPNHTMSSSQSSRQRDSATTSSTRPTTNTTRTKSTGVYDRDFQQHLIDNAVYPHEYEYPDGSVPAEPNNWEDLKQTLAQPRPSLSPSRFSDREFRNLKRADAHAAKEKQVSESVIPIIEGEIGDAKCRSGGIPFTNLDPLTDSTLKPGNPDIYYGARPEQLSRKVRDERGGYIIPSTQKELPIAPNCFLAVKGPDGSLAVARRQACYDGALGARGVHSLQSYQQDEPFYDNNAYTISSIYHGGRLQMYTSHVAPPRSSGGRPEYHMTQLRSFDITDTPETCREGLRAYRNGRDWCKDKLGEAIRQANKRANLEAEAPTGDAGASPALGFTTTVSHTEVNTMSHETGTSLNESSNVLGAFEESSSSIEDPTDYTLPAKRSGKRSSHQQSQRKRHNAGESSGTRHSHESTGTSISEGPSTSNTTVEQIVRWSWTSGHFQCHKGQDLVKKQNDTPADVWIYCDEGWPGQEGKKWRLWISAAREILYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS11</accession>
    <name>A0A6A6NS11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS11"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="78" mass="8181" checksum="9C31D4C7EF3221E6" modified="2020-06-17" version="1">MEPWVGGGGGSFLFLAITTLAGILALINTSGNGVSESGRLVSAQLVLISFLAGRFRAIYPFVFLVQAAYSVTNQSRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSB5</accession>
    <name>A0A6A6NSB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">White collar-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_290777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSB5"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658:SF18">
        <property type="entry name" value="PROTEIN GAT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="36"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="191"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="43831" checksum="67B343FEF4D0038B" modified="2020-06-17" version="1">MPPATMGGVGAGPLPTGFGMPTSSSTGSTLTEFTKRRNWSQRVLEELRDFLHILSPDGRILYVSPSCKALTGWEEGELLGKFVAKYVHADDTAIFVREFNESIATGNALRFFYRFKRREEGYAIFEAHGHPHLVVDPTTFGSAVGPGPGNTCSGFFIMSRPYPTKNATLLDSFLEHKIENERLTKRVAELKREEAEDEETVAQALQRKPGETAPAGSLTPSETTQRTDPVADAQSASQAAYNAMPPPAKPSVSNTALTRQNLDEALAASKPDSINDKMARYEGASHIETIEMLTGLRYRDGERSQGISTGDASPALIRGDAGIAILVDKDSRPGGDKKKKSKGPEEYVCTDCGTLDSPEWRKGPQGPKTLCNACGLRWAKKEKKRQSLATAQPSLPVHSSTNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSR7</accession>
    <name>A0A6A6NSR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin N-terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSR7"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="67"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="304" mass="33264" checksum="53D7B7837177E004" modified="2020-06-17" version="1">MSSTSTTTLLQGASLTIGSKSSLEGAPNSEDRPQWSSNFTSISTGGFAFAGIPKIDDLYRKRQWQLEHMAGAFRVFARKGFTEGTSGHISVRDPVDPNTFWINPFGKHFGMLTASDMVHIDEEGQVIGGNKTAVNAAGFMIHAAIHKARPDVHAACHAHSPAGKAWSTFGRPLDIISQDTCIFWQNQSVYKSFGGVVLAKEEGQNISKALGNHNRAIILQNHGLLTTGSTVDEAAYLFTLMERSCEVQIMVESAAIEKIHVGDEEAEYTYKINGDPETLYTEFQPDYEYEIWKSGGELLATKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT38</accession>
    <name>A0A6A6NT38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_99163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT38"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17584" checksum="E7D5C3C34D4D93E1" modified="2020-06-17" version="1">MSDGHHPRARRLLRAPLRMFRVRPVLESSASATRPSVSARLAGTLAYGCREQVKLSHRRSFWKDPEMSPCIRLAQSDAHPVCWSFQGGSEWAGDPRQGCTCSAVEVNCPLVCGKAVLYTAIALVRQGPAMHLKNTCQKGHGFTRGKGSTYPECPSFRPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI8</accession>
    <name>A0A6A6NTI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_351833</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI8"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22695" checksum="937E5E8B24E00AC0" modified="2020-06-17" version="1">MEVLLGITGADFTIVAASKAAMRGATILKSSDNKTRDLNKHTLMAYSGEAGDTVQFAEFIQANVQLYSMRNETHLSPSAVASFVRGELAESLRSRKPYMVNLLLGGVDPITEKPSLYWCDYLAALSKVPYAAHGYAQYYCLSILDKHHHPDINFEQGMKILRMCSDELRRRLPIDFKGLIVKVVTKDGIREEEFVDDKMITSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU13</accession>
    <name>A0A6A6NU13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU13"/>
    <dbReference type="OrthoDB" id="5390017at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="317" mass="34026" checksum="65647CF13382D9E2" modified="2020-06-17" version="1">MQPTMSLRSLPHLSRKRSARSVSSSEAEPDHDDKPAETEGYFQFSPRPSDSQVAPPAGQGTSRRSRSPSKPPATPREAPKRSRTDGDIDGLELVPKEDAWGIDVSTLVGSQVYLRTPEGGASTSDGGVWRGNWERFEQGRSPFLLAVMGGLDVQYDVLREAIPSLLTISPMLQPLVVHHSLPPTFSALSPPTLSHFSSSHAPSCPLISCPPPSLPLIVSPQPPSSLFLSLGLLHPLGGGLVPLDAIVLLDGQGRRRLVVPFGWGAGRHVLDGAGGKLVRERLTGVLVEAVKALERERTEEMEQSGVDPSADVWMEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU87</accession>
    <name>A0A6A6NU87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_351277</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU87"/>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="100"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="55797" checksum="6A7F5CD36B0FF2CA" modified="2020-06-17" version="1">MPSSALRPASFFNLIITLAFTFIHARFHLRLLPSLALLSFTFFITLPAATMATAPDRLHEGANAPAMPKPADWQDQTDLTQTIIVARATLVLLSTIAIAIRCYTRKFLDRKILLEDWLTVLGWALWMTYVSVTSFFDQHGGGLHQWKLTMADLAEMLKWIYISAILYGPTVTVIRAAICVMYMRMFVTRQGKNYFYWGAHAILWSNVITYSVCTAFQIFACHPRERYWGGHRIDGWCFNIDAMNIASATFNSISDFALLLLPQSVIWKLHLPVRRRIGLSLIFIGGLGACACSVVRLAYCVILLNKVDLSYYLAAMGLWVYAEIAVGLICASTPTFPRFWKHVAPKLARVGGKIRIRRRLGGRINSRGLSDTALSFPPTPTESQRDALDNSEELGGGKYLGHPAVPPPSAGVELRDLPPVRRGPHGRPMPAPLHDPFPFPTFSRDGFTRVDVQGGLRAPFPSPSLPHPARGIRRTVEVTVTSRCASSVARSEARGAEAAPHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUB5</accession>
    <name>A0A6A6NUB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_373543</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUB5"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001164">
        <property type="entry name" value="C2H2 finger domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="745"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="397"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="759"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1166" mass="127200" checksum="B1EFF1EC005D712F" modified="2020-06-17" version="1">MSAQILSMHPAHAPDFGKAREALTPLRSADGPAMAGASAAAAAAAASSIGGHPAPSASMTPGGPTPMEDVTKSPVSDDASRGRRRTRGEGDAADGETDYNGDADAAGAAGSSRKRRRSRKGLDKKFECPHEGCGKSYSRAEHLYRHQLNHNPKQIYHCDFPDCNRSFVRQDLCARHKERHTARGSQLLRKDTFMNNLNPIVTGALANKNAVLGKPPQGSPPVRPGDGQYQTTILNSNGIGGKPSDRSFIVQSPASAVPSSATAGSEISPPLDAQLHSPAAMHAVNRSKSDDMYRAADAPRPYEMNTPRSGPSYGPGGPQRHTSFGSMGAHRPQISPHTRPTDNFSRPPLPSQQSVPGSVQSNPMHSPYGVTPTQQPQQYGTPQQQASGSGHFPSPSPATYQSQQNFPQFTSLPPPTFTTMSQAPTSRDDSQYATSGTPRAMQGIQDVSSGANDNRMSGVTDAFEPSLQQQPYTMPVFGGDGLGRSPFAMADDFTAWLFNDSQFNNSPMGGYPGAGNMSNMMGSASIGLQAPYFNYDGAVAGYLPQPAPPQHPMAVNAILDTSLPESALSESKRQEIIDLITMRFNETDHAPVRKQKEELLEGDKDNETHVLSLHMMQVYIGSYWLHFHPQLPILHRPTFNADACPDLLLICMMALGASCLEKNHGHEVTNACSELASFLAWHVRWEIFMDADFRPPAKLWIFQALLLLEIFEKMYSTRPLHERAHIHHATTLTLMRRGSSLIGRSALDSPPSVNKDAKQGSVSSSNGSAHASGTNTPDEWWHHWITNEATRRAAFAAFVMDSIHATMFGHSAVMVAHEMRLPLPCDEALWSATSSAEVGRVEASLHANGVKPTTFLDGLKKTLNGQPVRTNSFGRTILMAGLLSVSWHMNQRDLQVSSLGVSQALGGRDKWRGSLTRAFDFWKRDFDESLAKSNDLAAPGAYSYSNAMDDDNVFESRTVLHHLAHMAMHVDIVDCQIFAGAPRLLGRSITNQDYQGAKRRMQENWAPTARARDATFYALRFLGAVLLPEDHHHHHGGVQAGSPPSALSLDYSARDDFLLNRPWVLYFATLIVWSYGFALDGPIRRPYGLASDEARLRDMGDFLRRVGGVRAPDDLAKTAERNRCLGLLMLMRDMFRKTRWELLHEASTLLNKCVEMLAPGQGQSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUL1</accession>
    <name>A0A6A6NUL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="7">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_350815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="7"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUL1"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00788"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000004">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000012">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="36426" checksum="E6DB5E02FE9A96EE" modified="2020-06-17" version="1">MSGPLRPIYTRMNEAEANASQMSSPTGTVMDAFEPTYDFHEIRDTLVSVAQVAGDMMRAADPSVREDSDTKRNSADRVTECDKAVEMMVLDRLTTKYPSFDFLGEETSKAGQTLGDGPTFVCDPIDGTLNFIHGFPNCAVSLALAIERKPVVGVVFNPFRRELYSAIRGFGATVEYADGSVHSLPTSGPEPPALSRGLNGCLVALEWGSERQGPNWELRTGMAIKLLSAQATGGAMCHSVRSSGSAALDLCYVAAGTIDAFWEGGCWAWDVAAGWLIVEEAGGLMASANPGDWDPTVEGRLYLAVRGASGGREEVVEEIWRHMGERKFVFGKKHASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUW4</accession>
    <name>A0A6A6NUW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_289802</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUW4"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000010">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="11 12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2455232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="136" mass="15312" checksum="3EC87E4296E97578" modified="2020-06-17" version="1">MRSLTLFTGKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVEAYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVH3</accession>
    <name>A0A6A6NVH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_323575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVH3"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF190">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="508" mass="57593" checksum="3FF7D4CF274623FB" modified="2020-06-17" version="1">MISQQIQLENVHVWDFAWFACGAAVLLWILKRMLDEIISPLRKLPGPFMARFSRLWYLKQVWKGNFEQTNIALHRKYGPIVRITPNEYSIDDVEAVRNIYGHGTNFIKSPWYYASGRPGQSPSKDLFTDRDAKRHAANRRKVAALYSTTNLMKMEPAISECTDLLTERFLELAKSGAVVNMQHYLQCFAFDVIGLVTVGNRFGFLDNGQDKLDIFSDLHAYLRYCATVGIFSEWHRIVFKIFQLLSSKGMANMVKFTNNQIQERLAADDIEGKPTSNDDFLGRILAMHQEAPDKFSMENVFTVCLTNIGAGSDTTSVSLSAILHNLIVCPDSMRKLRAEIDEKARSAEISNPVTYQESLKLPYLQAVIKEGLRMHPATGLPLGRVVPQGGATIAGSYFPEGTVVGINTWVAHSNKHVFGEDAEVFRPERWLESEERTARMERYHLAFGHGSRTCIGKNISLMEISKLIPQLVRTFDFALANSGEKLETDNVWFVKQKNFYCKVAVRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ0</accession>
    <name>A0A6A6NVJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_68288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17562" checksum="4DA7075C6D453216" modified="2020-06-17" version="1">MCGREPDVGEKRAVGRALDGDLRSGAARLAEDQRSCSTFDARDAVFLPLATPATNDVSWRGGAVTRRRHRRPGSSCASAAPLQFPNRTENGQRYHGSMHDAGSHGARLEEFQLYNANRRTCYRLIMLLFITAYERILHNALTGSASLSVCLHSIKKRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVK2</accession>
    <name>A0A6A6NVK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_348559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVK2"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025455931" description="Kelch repeat protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="55870" checksum="754221CCA5467C08" modified="2020-06-17" version="1">MTLLLTLLYFFAGTLCANHDAGPNNQMNDGLQQVRRQSEGLVDLTQVVGHKLAIVGDYLHIHGGWAEYADPGTGNVTYGGSGPPQPRTLSIYLGEPWDSEHVEINIIDSSDLPHFLNQEVWMDPSGDSFWAWGGQYQDGPHNLNPWRFTPDGDGGGSWEEVPMEGADGYDALLKPIQGAVTVTGRDTAYILGGQARQEPLEEYHSEFLKGLVSYDMDANSWANTSAGCCIESLVQDDHIQGFFTPSFGANGLLVYVGFWWTPESQVDMGTVKFYDPETDTWNSQATSGETPFHRVGYCAIGVESPDGTYEIYMYGGMPIFYWEFDEWPEELWILTLPGFHWMKADIAMTGSFRFKQQCIRAGGRQMLSVGGELRLEGPDLMPLSYILDGGVYRHHLPVLDMTNLSWSNEFDPDMDEYDSPQMVKDWYSEGNLDDVPWFNEEVKSLFIRSASTQPPSTRATATDISPTGFAISTGVTALPNTSDDGAGLPQVTAGAVAGGAALAILLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVR9</accession>
    <name>A0A6A6NVR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_386902</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVR9"/>
    <dbReference type="OrthoDB" id="77989at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="456"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="63302" checksum="E9AB895DAA88DA16" modified="2020-06-17" version="1">MSTSRDAPNPLRPYYVPPPSFGTADPSSHDAGSGNSSSSHFYYRRSPTPPPHTSRGAAGRSRLGASARDILSDLDYDEIVGESGPATLADWAKRLADQAVWNYTSVFLSQPFEVAKLVLQCRMISGQELGPGGVVVARGTGPGVHSDDLNSSDSDPENPSYFTSTTPSASRQHASTRRRPATPPRSESTTPTPPSSRRAQQPPIYHPYQTHRYKLALRRPDSLLEILAQLWSKESAWGVWKGTNVSFVLNVLQRTVESWTRSLLAALLNLPDPGSLSGSAGSSRSGGALLPGGSLDVADSPSPWVSVGVVVAAAGIAGLVLAPLDIIRTRLIITPSSPPSSSSSPTSPTSLTQSSDSSPHHQPRTLIPSLRALPTLLPHPTLLTPTFLHATLPSLLAASAPLLLRSAPLRIDPLHSPSAYSAATFLAALAELAVKLPLELVLRRAQVAVLQEWAAETQQPQQAPLKRKKRAVAPSSGSRGRQPRRVGEPSPSPRSETGAAPSDEDAALPTVVDVGPYRGVFGSLWFVVRDEGVSVVGPPPPLRGGGKRLGPTPMSGMAGQQRLRKGQGPAGLWRGWRVGFWGLVGVWGAAALGGAGGGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVV2</accession>
    <name>A0A6A6NVV2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_365089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVV2"/>
    <dbReference type="OrthoDB" id="4770059at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="38112" checksum="A235DFF2DB3566EF" modified="2020-06-17" version="1">MGPALLPGESAIVCCPSSSSGYGCLEPSQCSKSYVTTVTSTLYPEPDFSTTGDLTVYTSAQYTTSNVYAIQVRWQASDLSVLETDPLRPGQSPTPSTSSSSIIPLQTGENSTINADSDDSSDNSGLSTGAKIGIGVGVPVGVLAVAAAGFLLFWRHRKRKQARQPVVLNQSGAANNTAYPGPHGSDPNAGPNMAMASGSPTHYDYHGGYMPAPTHASVGSNNTTWYAPGPPPHLSVSDNNSPSSGHGSPGVNASQQHQYPYGHQDQQYQYAQQQPQQQQQPHPHYMAAVNPETARLHTEQGWLHERRSRLEDMQRIENEEERLRRRQEELEELEAARQRSASLQAGGGAHARTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWU7</accession>
    <name>A0A6A6NWU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_57405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWU7"/>
    <dbReference type="OrthoDB" id="5372703at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="269"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="461" mass="50727" checksum="BE62A6ED9A001DC1" modified="2020-06-17" version="1">MASPPLHHHLQQNRYRCISPRCAMKRSCRYLSDLPTPPDSKRLHTDGSSPETNERLHTGEENAALRQTCSASAENSKYEFITRWREESAVVMDHSNSSPGRKFAAFAPCPSPMESPGQAAQSVLTSVTPAHSSTNQSKSSAKRPSPPLFRGMLHAVGIGIVLRGLPDTHKAEVDRILGRDGQRGHISDADRAAADIWRNRVIEILGGTFIESDLVNALMVMLLSLSPMSRLACSNCNEWRKDATTSGPGKGPRESSADFNLATRVEDTYIPTPIEGPRPDIAVGLSFKKAVRPVLGRVKASVLPTLQEKNVLVGEPTFQARDLYFPFLVAEVKTGATSGSLFEAQNQAAGDATRAANIFQSVRARAIEAGWQDNGRPFLAPPFIFALTVEDSVVELWVHYFDAQERFFFFTKLGTWDAVDENSYRQLVGMLSRILLWGESTVQPLALGQLKFALQLVDPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX34</accession>
    <name>A0A6A6NX34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_422386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX34"/>
    <dbReference type="OrthoDB" id="3944675at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="244" mass="26704" checksum="114588BCF0F3942D" modified="2020-06-17" version="1">MVIYRREAKPNRETEEEFEQNTVGLQDQGLCRKYLGTTRGLTGLEICEPQCGDLATGDAHSVTCSADTPGNGTPLYTDPEGNQYTIGECICAMPFVEELFQEIVLALPAIGDIGCAILKNALGLVLEYGPLGIPGVGTVISVGMRAAISAAKTFAENGLGSQDFLDWLFPCGNRNLRDGLQKGARLPGRLRRPESRRFSGRVNEGRFSFDGHFSCESHFHETRQSKLEGHFHYEGDFSPGHFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXB4</accession>
    <name>A0A6A6NXB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_288967</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXB4"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="15"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2455903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="24457" checksum="E5EE5BD5B6912E4B" modified="2020-06-17" version="1">MQKAYEEWNRALVNVKQTCAVCTDDRGRSAFPSRITVKCKHKSNTCRACLSQWLSSELELKGWDRLTCPDCGESLDYNSVKKHAFQETFQRYDQLSTRAALSTIPNFHWCLKPGCGSGQIHEDSEGPLFLCTTCQSRFCIVHNEPWHDGETCAQYDKRRRYQANNSMRDEKASEKWKKSNSRLCPMCCAPIQKNGGCSAMHCGFAARCRVKSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXM3</accession>
    <name>A0A6A6NXM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_267925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXM3"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF105">
        <property type="entry name" value="F-BOX_LRR-REPEAT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="171"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="707" mass="77602" checksum="D7634C43C5401862" modified="2020-06-17" version="1" fragment="single">SPSPTPPASDAIPINQPQAKLKGRLRLMRSLQRISSSPSLAKAGRSHSTSAAYRAGGRGSISCVSLSAGSRAGSPYDNSYGSSCSSEMSAGYSTAPTSVSSTPAPDGGFKMARVCSSGLDSPTYVGLPLDRRPTSRLGTRDGELSEIEEGYFLRPVAEDKKKARFKKRENFNFWGDMPPELRIDILRYMAPKEIVRCSSVSKAWYRMCFDGQLWARLDTTEYYRDIPADALVNIITAAGPFVRDLNLRGCVQLRERWNLNGLVDACRNLEHFSLEGCRIDRTSIHCFLLQNSRLAHINLSGLPGATNAAMKIIAQNCPRLEHLNISWCNNIDTRGIRKVVEACPNLKDLRAGEVRGWDDIDFMLELHHRNTLERLVLMNCNSLNDESLGALMEGMNNEVDFLTGRVMVPPRKLKHLDLTYCRGITDRGILTLAHNVPSLEGLQLSKCHVLTDTALTALLPTMPRLTHLDLEELDELTNATLATLATSPCHATLRHLSISYCESLSDVGLLPVLKSCARLATLDLDNTRASDLVLAEAAAAIRARNRGARGLSGNERPSVGLRLVAYDCANITWTGVREVLSRNAEITRPMAAPGISATSGPPTYPREIIQLKCFYNWQPTVEEHTKRVLRGDFAAAARLERKWANWMMLNEEVGAGGGGARRRRRRAREAQLLHADEEEGGMGGVGGTGVVGRRRRARSGPGGCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXU4</accession>
    <name>A0A6A6NXU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL14m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_287505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXU4"/>
    <dbReference type="OrthoDB" id="274765at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000005">
        <property type="entry name" value="50S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_uL14_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="18059" checksum="3675C2BC8CFC5B15" modified="2020-06-17" version="1">MPLSTSILYPACVRPAQHVVRKITRAYCSHIILALRQTLLNCIDNSGAAVVECIQLIKRKRPAGIGDRIVVVVQKQRDFGSDRSSVSISNKVKRGDIRHAVVVRTRKQRQRPDGSVVKFDDNACVLINKSGEPVGNRLTSIVGAELRDRQWSKILSLAPMHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXZ9</accession>
    <name>A0A6A6NXZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell division protein anillin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_287904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXZ9"/>
    <dbReference type="OrthoDB" id="2123378at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13278">
        <property type="entry name" value="PH_Bud4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000311">
        <property type="entry name" value="GTP binding protein (Bud4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="551"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="357"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="676" mass="74917" checksum="CAE9A1FA8F97CB19" modified="2020-06-17" version="1" fragment="single">MARQRRIASNSDHDGNDNGDDSAAPPIPERSPKRQSLLVPEGEDGDVHGDLHSLEAKNKGKPSRRESFRGLALDVPIDEGSEDLSFGLDKEFDRVIEAQKVWFENLLSCGSLRTACERDVENGLPKMDQVVEARPQPSRTHSYQSQLSTGANYISRKQKGYLMRQNTKVVVASSRQFSDEKPPPTPTLEPSAAAANDDPRGGTRSAGNSPRKPPHERTKSWTTEPWNGKSRRRSVKGVGRKPPSGPAPPMPGQESAMGGLDTLPENGVPVDEEECMGGEAEDGERGRLFVKVVGVKDLDMPLPKNERTWFQLTLDNGLHCVTTSWLELGRSAPIGQEFELVVLNELEFQLTLQTKLEPPPQPAVESYPSASSPTKTPKQKSAFSRLLASPRKRKEAAKEEAAAREAEAAAAAAAAAEARRNARDNPDATAWELLHDLVASDGSFARAYVCLKSFEDRAFGRVLDIEVPCFNEWAIEDSEAVANSVRSKSKGAHSSTQVHGVGVVRRPPYRIGRMQLQLLYVPRPRGALEEELPRSMSSATRELREAEEVKGRLFEGCLSQQGGDCPYWRRRFFRLQGTKLTAYHETTRQPRATINLSKATKLIDDRRQLTQEHVSSRGGGRRKSAFAEEEEGYMFVEEGFRLRFANGETIDFYADDAASKDGWMKVLEDVVRSNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY72</accession>
    <name>A0A6A6NY72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_40952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY72"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="18392" checksum="1A29E45F36B6E9CE" modified="2020-06-17" version="1">MVPSANIADAALEHAPHQQVGGGNGAMVTVAVIHGWQSDATRQDQAVRGAATKSRLSTRPWAGAARKQERKTCWWTGKRLVGMVGRGEGKRKRESGCGSAGYLSDRRDVPALAGAARGCRAKKSQSGAVPACGGRLAGPAPGERLPDILWVEAARQRATKQGRPYLSGAFISPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYJ1</accession>
    <name>A0A6A6NYJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Inositol-pentakisphosphate 2-kinase</fullName>
            <ecNumber evidence="3 9">2.7.1.158</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_346083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20313"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.158"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="9">The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IPK1 type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.158" evidence="3 9"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYJ1"/>
    <dbReference type="OrthoDB" id="272370at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035299">
        <property type="term" value="F:inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009286">
        <property type="entry name" value="Ins_P5_2-kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456:SF2">
        <property type="entry name" value="INOSITOL-PENTAKISPHOSPHATE 2-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06090">
        <property type="entry name" value="Ins_P5_2-kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="436"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="464" mass="52459" checksum="28A0682BA00D0B83" modified="2020-06-17" version="1">MSSAPPNAGNSLVDDLHGAFADNTIWLDRDVSPSVPASFIRFQYLSEGGANVLLSLSPDLSGGKTGYREEHKPLLEGKLLRLRKAVRGFITAKDIFRFHQSVIQYFFSADEVVEYTLLRVNNSFLAVCNENLQRLAEHQLRTADRTDGCLIGSQDDFISALFVTDMTSHFGPTPDPRGVAFFPTAESSSQRLVTVEFKPKWLIQSPTAPQKARRCRTCALRAKRQATKHRSSDKEFCPLALVDSKGPSAHTLAESIVRAQAYYHELDPAQLDHLTKMLSSFIQYERTNDRLLQKLKNLQMRLSHPLSRTRKCEDVSDILISMTLRDCSLLIRFDIASVGGEHVEPEAKLADLDFKSHGLLVDHYCERNSAVLVETVKALDNPKLVDHELRAARDDLYDRLRTWSEAEEHLIRAGWYTGDENCKLDREICVLWKERDGAETESATEPEDATRNRVVRSNSLKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYJ6</accession>
    <name>A0A6A6NYJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYJ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="21704" checksum="1FCCC6D9828BAE7A" modified="2020-06-17" version="1">MFQALQQKPMIVSPIFGHVWRKTNITSAFFSLFLLTPPEIPLTIPSEHRNENKTKIKTRPSSNCPRLCSRHSSAVPPPAASPSFLKNWPTGPRSFSGGGAHPPVEDCCSCCCCRRPLSCSRACTRALAASLGSSSLALSPSETRAGGSGAGEADGGGAARWLGLVSGVGEEVIGPLVGSGSWELDLRKKWKGMFFCVCVSIRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYQ4</accession>
    <name>A0A6A6NYQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="4 11">4.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_322306</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2</text>
            <dbReference type="Rhea" id="RHEA:10792"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="4 11"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYQ4"/>
    <dbReference type="OrthoDB" id="15425at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000037">
        <property type="entry name" value="Phosphoribosylaminoimidazole carboxylase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016301">
        <property type="entry name" value="Ade2_fungi/plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054350">
        <property type="entry name" value="PurT/PurK_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004679">
        <property type="entry name" value="PRK06019.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609:SF5">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609">
        <property type="entry name" value="PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22660">
        <property type="entry name" value="RS_preATP-grasp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001340">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="110"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="572" mass="62752" checksum="9C6B1E147801C62D" modified="2020-06-17" version="1">MDQVVGFLGGGQLGRMTIEAANDLNIKCVVLDQGHSPAKQVLAHAEHVDGSFKDPASVKKLAEKCTTITVEIEHVDTYVMEEIEKDPNFRAKIEPHWQTIRTIQNKYNQKLHLHQHGVRTAEFEDLEGKSEEDIKTLGQKWGYPLMLKSKTEAYDGRGNFPVKSDADILEAMQALGGRPLYAERWANFKAEVAVMVVKAKNGEFAYPPVETVHEDSILKLVFAPARNVSKGVLQQAQKLATKAIGTFKGKGVYGVEMFLLEDDSLLVNEIAPRPHNSGHYTIEGCYMSQFQAHLHAILDLPIAQEDLELREPSIMLNILGGETTDSHEKVKMKALHITRKAHIHMYGKGPARKGRKMGHITVTAKTMAQAEALVQPIVDIADEVRGKPQKWIQLQPSSQSPTPLVAVIMGSDSDLPKLEAGIRILDKFSIPYEARITSAHRTPVWMAEYAESARLRGIKVIISAAGGAAHLPGMAASHTCLPVIGVPIKASNFDGLDSMFSIVQMPRGVPVATVGVNNSTNAALLAIRILGVGDPEAWDKTVAFAEQNKNDVLAKDVRLLEEGALAYLQKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYZ7</accession>
    <name>A0A6A6NYZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin 26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_288017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYZ7"/>
    <dbReference type="OrthoDB" id="3981028at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48870" checksum="3DA2915834C3BF05" modified="2020-06-17" version="1">MLSSTSSLTSSAHLHPHQNGARASSQIAKTYRQAAQLFLTRRLPEALSTIEPVITPQSTPATVDEGNEYDNASSMELVVPAPITSASKGTRIKVWSFYLTFLNAVVELGPEEGKHAFGSTRWKALVAKAREGAVWDEVVNVGYHGIEADVDADVVINLATLLLTHMPSQYFNAAHLESYLAATSTPNFNIPASAFSPQPGSRSSFPPGSAARTPPARTPVAASGTTTPAGLHSRLKLLELYSLHVLPALEQWDAAREFIQMSDTLDDERKDAFILALHGLKAERETAREREDEVRRRQEEQWRRKEEEERRRQREEEEAEERRRVRREEEERRKRDKQQQQQQQRDRARQGQASLSPPHAAAAASPAKALYQRAAALCSALLLKPLNALATNPLAALRMVLFVLALALALGRRDVRERLRRAWEKVKSTVGVGVKVSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ60</accession>
    <name>A0A6A6NZ60_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="5">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_257342</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="5"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ60"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025620132" description="Pyrroline-5-carboxylate reductase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="8">
        <location>
            <begin position="41"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="9">
        <location>
            <begin position="196"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="86"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="312" mass="31674" checksum="8B8B243F478E9CD9" modified="2020-06-17" version="1" fragment="single">GTMGIAILSGIMSSLTSTTPAPTAPGTPSAEEPPSRLPTRFIACVRRAQSAQRIKAQLSAYASIPLRVVVDDNVAAARDADLVLLACKPQMYRDMLAAPGMAAALAGKLLISILAGVSVRDLEDALYAGPGPRGPGAPALPPNPCRPVRAMPNTASFVRESMTVIAASDPPLPPAQAALVTWIFARIGLTVSLPASAMDASTALCGSGPAFFALVLEAIADGGVAMGLPRAEAQLMAAQTMRGTTGLVLGGEHPAILRDKVSTPGGCTIGGLLVLEEGRVRGTVARAVREATVVAGQLGRGVQGVNGTRFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZY0</accession>
    <name>A0A6A6NZY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_286572</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZY0"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF382">
        <property type="entry name" value="LOW-AFFINITY METHIONINE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="628" mass="69586" checksum="E01F529B4597CED7" modified="2020-06-17" version="1">MASDFTPTRNDSDSDVIFDEDEDPSAIHTSTPDERFRLGLYDIMGLVINRMIGTGIFMTPTRVMQGTMSTGITLLFWFAGVFYAFAGTHLYIEYGLNVPRRIFDGLEQGVPRSGGDLNYLQYIYTWPRYRKNAVLFSTCLYGIAFIVLGNMAGNCINFAQRVLQASNVNEPSKGAVRGIALAAATFSCFIHAFSRRGGISLNNILAIMKVCILLLIVIAAIIFGSGGFKNSQVQTTQNLDAQNSFDGASSEANGYAHAFLAIIFAFSGFEQPNYVLGEVSRPHRKFPIGMTAAVGLVCALYIAVNISYMVVVQRDDQIRANVAQQFFELTFGSLSADSHTGGRVFNAFLAISSLGNIIVMTYTAARVKQEIAKEGILPWPKFWAKNSDISLGRLLRWARRTPSVFRVFHVVLKMRWLAPEEHSEKTPVGALLLHFLSCVVLLFTTYGLTPGNAYNLLTGLASYSLFAFFGVFLALGILYLRLRPSLLWKEKSPGFSPILSVICASVYLVGNLFPLIGTWIKPAGRFGDLIAGGFNTETLDWYIMPTVGWCCIALGALWWLGFLVYAKRVEKRTGTVFTVERVPEFERDPPDTGRPVQLHETVYLAWVAKENEKSGASSDDRTPMMDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZY8</accession>
    <name>A0A6A6NZY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_287250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZY8"/>
    <dbReference type="OrthoDB" id="9999821at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF3">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="151"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="385"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="466"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="734" mass="81232" checksum="E71D7BC5303EAAD3" modified="2020-06-17" version="1">MSAAQQPSAASPAVNTTVPEQQQNGAAGVGRGPQIVSTSEALEVLSGPLLNYKRMSKSAGSGTTWHGTVLLVTTAGQRDPQLTLRFSRPVSGNPSAAAPAPERTVGGTKLYEDPKKCFFRFDLDVPFADFEAMWEYSIPGVKYVSADSVAEPKTCTRSFAVPARNQSMRIMFHSCNGFSVGTDMAVWQGPSLWNDVLRMHAQEPMHVMIGGGDQIYNDSVRVDGPLRPWTDIGNPHKRREFPFDEKMRAECDDYYFDNYARWYGTEPFKTANAQIPQLNIWDDHDIIDGFGSYTDHFMRCAVFRGIGGVAHKYYMLFQHHIAPPRSTFTTDAPKTMHTEGTTPADFAQLKDTFVLTETSEDPSYIIGEKPGPYVEERSRNIYCQLGARIAFLGIDARTERTRHQINYPETYDLIFKRASAELSANKDIKHLILLLGVPIAYPRLQWLENILRSPIIGPLRLLNKRFGIAGGFFNQFDGSVDLLDDLDDHYTAHQHKHERRDLMHRLQELAKQHSVRVTILGGDVHLAALGRFYSKPKLNIPAERDFRYMANVISSAITNKPPPAAVANLLAKRNKIHHMDHDTDETMLELFNHDPGMGKNGVNGNANLNGAEIAKKTNDSNHTTMPSRNYAIIAESNPEAAASGASAAAAADGENPRVPNPDPRHQLHVGEVNAGTDHPAASGLRHTGLCGTYGLDVTFRIEISPKDTEGRTEGYGFSIPGLEASAYQAEGSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P000</accession>
    <name>A0A6A6P000_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L33-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_345599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P000"/>
    <dbReference type="OrthoDB" id="1166329at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018266">
        <property type="entry name" value="Ribosomal_eL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01105">
        <property type="entry name" value="RIBOSOMAL_L35AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="12232" checksum="606B741392ACFB68" modified="2020-06-17" version="1">MPSGQGHRLYVKGRHLSYQRGKRNTNPGTSLLKIEGVDDTKAATFYCGKKVAFVYRAQREVRGSKIRVIWGKVTRPHGNSGVVRAQFRRNLPPKSFGASVRVMLYPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P042</accession>
    <name>A0A6A6P042_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">UDP-glucose:Glyco protein glucosyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_343671</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27683at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003980">
        <property type="term" value="F:UDP-glucose:glycoprotein glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06432">
        <property type="entry name" value="GT8_HUGT1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000065">
        <property type="entry name" value="UDP-glucose:glycoprotein glucosyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040497">
        <property type="entry name" value="Glyco_transf_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009448">
        <property type="entry name" value="UDP-g_GGtrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040693">
        <property type="entry name" value="UGGT_TRXL_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040694">
        <property type="entry name" value="UGGT_TRXL_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040692">
        <property type="entry name" value="UGGT_TRXL_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040525">
        <property type="entry name" value="UGGT_TRXL_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226">
        <property type="entry name" value="UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226:SF0">
        <property type="entry name" value="UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18404">
        <property type="entry name" value="Glyco_transf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18400">
        <property type="entry name" value="Thioredoxin_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18401">
        <property type="entry name" value="Thioredoxin_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18402">
        <property type="entry name" value="Thioredoxin_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18403">
        <property type="entry name" value="Thioredoxin_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06427">
        <property type="entry name" value="UDP-g_GGTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025489145" evidence="10">
        <location>
            <begin position="26"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="11">
        <location>
            <begin position="39"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="12">
        <location>
            <begin position="266"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="13">
        <location>
            <begin position="403"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose:glycoprotein glucosyltransferase thioredoxin-like" evidence="14">
        <location>
            <begin position="659"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="Glucosyltransferase 24 catalytic" evidence="15">
        <location>
            <begin position="1201"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1472"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1491"/>
            <end position="1502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1502" mass="167807" checksum="9EFCEB4BA0DD14C2" modified="2020-06-17" version="1">MRGLSRPLRAAGLLSCALLPLAARAIPSINVALQASFSSPPYLLELLETAAEENSTAYFPIVDRIADGYLAQTSTDRELYTTFLQLLQSDGHLVDPDALSSFQFALAVRSTAPRIEAHYQYYNTSVEAPQGDGCDIWVAADGKRYCDAELATPHGSVADGARELPFDRVKDGRSNMELPIVLYADVTNPRFGPFYKELARTVQDRRAPFVLRYVPPPNRDEAQRISVSGYGVEMALKRTDYIVIDDRDAEEARADSEGRESEQDGEVADLKPLSASDVARLGMKAANFVLDSEDPFKTLIDLSQDFPKLSSAVVSHDISEEFKNEHIGNRERLLPPGYNMIWVNGVPVQSRKVDAFSILENIRNERHLVRGLTSLGLEPEEAIKLLMHPEINEVLADEEPQRFDFRDGIEGGGVIMWMNDLENDQRYEGWPSTLASILQRTYPGQLPPVSRDVHNAILPVDFTNPKDVALVVEPLQSFIKRKVPLRWGIVPITNSPAAAVQARIVYHLLESYGLDAMLSYLQRSLASGQISSPEKAHFDPVIAGRSLIEGAVERSFEEVLQHDDVAVKLEGAAKYLDRLSVNFSPAPFIVNGAIVPRSDDWLTSLSNRVSMDHRSIQRGVAENVFEESTWLPTYFLFQAVKRRHPAVVPDDEINVTFANVGAIFTKHKETLDGVLRIPAETKDSDIESWAQMLLCLDFDSENGRRLLSEAIEFRKAHPSVEVLFLPQLAHQFTDGSLIDRMERLRNQQMQPTDALDKIAATLADGATKQTSQSGNKFDEDYVSAISAVSRDLGIESANSGPVVVLNGRIVRVPINGDDFTKDDFETLLSYEKRKRIKPWARALKELGLEAKIKTPSASAIVTSIVAVSSASDEDPDSMFEASPKVRMSAFELWNTTKTAILTGNKKLSTIQIVASIDPSSENAQKFIPILKVLSELKGIHLRLFLNPRDHLSELPIKRFYRYVLQSEPSFQENGELNMAHAQFDGLPAETLLTMGMDVPSNWLVAPRESIHDLDNIKLGALRAYSSIDAIYELEHILIEGHARDFTLRKAPRGAELVLGTQKDPAVTDTIIMANLGYFQFKANPGVFNLALRPGRSSEVYKMDSTGLTGQHRGASDICLTSFQGVTLFPRLSRQPGMEKEDVLEPSTAGSAAVDIADSVLSKAGIHGTKDYINKGLKFGSDLLASAGLSSQGVKPSRHADINIFSVASGHLYERMLNIMMVSVMKHTNHTVKFWFIEQFLSPSFKSFLPTLAAEYGFSYEMVTYKWPHWLRAQKEKQREIWGYKILFLDVLFPLDLDKVIFVDADQIVRTDMYELVTHDLKGAPYGFTPMCDSRTEMEGFRFWKQGYWANFLRGRPYHISALYVVDLVRFRQLAAGDRLRQQYHSLSADPLSLSNLDQDLPNNMQMQLPIHSLPQHWLWCETWCSDESLAEAKTIDLCNNPLTKEPKLDRARRQVPEWTAYDEEIAALARRTKAGNVPVGEDAGSPGTAEAKSDASREKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0A1</accession>
    <name>A0A6A6P0A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome quality control complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_320628</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0A1"/>
    <dbReference type="OrthoDB" id="207084at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.310.10:FF:000003">
        <property type="entry name" value="Zinc knuckle domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="8">
        <location>
            <begin position="551"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="9">
        <location>
            <begin position="986"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="689"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="335"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="927"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1123" mass="123351" checksum="99595A0C1D01F568" modified="2020-06-17" version="1">MKQRFSSLDVKVIAHELSSSLSTLRVSNIYDLSSRIFLFKFQKPEHKEQLVVDSGFRCHLTGYARETAGEPSGFVKVLRKHLRTRRVSAVRQVGTDRVIEFEFSDGLYRLFLEFYAGGNVILTDADCKVLTLLREVNEGSEDDKLRRGSTYRLDLRQNYNGVPPLTKGRLRDGLQNAVERQTAAAATAKAKTKAKKDALRKALAISITEYPPMLVDHALSVTEFDSSVKPEDVIKDEALLEKLLSALEIAGQVVTRITSAEITTGYIIAKKKRPYPEKRDEQNAAAEDESLIYEDLHPFKPHQFEKDEGIVFLEHSGFNRTADVFFSSIEGQKLESRLQEKEINAKKKVESAQAEHERRIEGLKQVQDMNVRKAQAIEANLDRVEEATAAVNGLIAQGMDWVEIARLIEMEQSRGNPVAALIKLPLKLYENTVTLKLSEPTKEDDDYEGDETESESGEDEEYTTGNGPSKISAKDDKRLAIDIDLGLSGWSNARQYYDQKRSAALKEEKTIQASAKALKSTEKKVTSDLKKALKQEKDVLRPLRPQLWFEKFYYFISSDGYLVLGGRDPQQHDTLYHRHLRKGDVYVHADLDGAAVVIVKNNSDTPNAPIPPSTLSQAGHLSVVTSSAWDSKAVMSAWWVSYDKVTKTGLTGEYLGPGKFVVKSDKNYLPPSQLLVGLAVVFQISEGSKANHARHRIQEEVDGQPEPSTEEASAADDSKERPAPAKEDSSDSDEEEFPDAKLDSNSDDSENEDHQKAQLNPLQTGVVPDADDQIQTSVSREESTVSLAVEDEDRTSSTESSTRPAGGGSKGHLSAYQRRQLKKGKDPLPPQMQSPAPSSQVASDYDLDDDDYTTTSSRQGEPPGPASITSTSVSNKPLPRGKRTKAKRLAEKYANQDPEDRELALRLLGSKGPGSTSAQAAEDKQQKPSAAEQAAAQKARRREQHLRAQAAGRAAEARRHGEQQQQQGEGGGERADEEAVDHAVDVGTFTGRPHPADDIVAALPVCAPWAALASYKYKVKLQPGTVKRGKAVREVLGRWEADGKDAKKVDRDGRDPDRIWPRERELMAGWKEESVVGIVPVGKVRVMMGGGGGGGSKGGGGGGAKGKGGGKAARGGKGSKKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0T0</accession>
    <name>A0A6A6P0T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0T0"/>
    <dbReference type="OrthoDB" id="5426191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="556" mass="60052" checksum="D1F24BA5D4E806F8" modified="2020-06-17" version="1">MASAVQARSLSSLISLASSPPQYPRNPALPALDRVVLYITRVPGSRDVFLTPIKPREKIVTAEDVCSSLYYVHVDDSNDGSDPPDGVLMSESNNRASHAGPREYTRAAGRKPLPQLPLEPQLSAEEHPPLSPRNLMPPPPLPNRLADSTVAGSNRATVSRKPVGSNHRHRKGFSVDIPFRPKQENMKENVKHSIDTGIVPPHVCHTGRFSEELDEDSLRGNFSELNSSIDQRSPQRSTPANIANLVHNTGSGVTLILIRRDPSSGAQWNVAKMRDYSTFAASTHRPQITATHKTKSDCAPVDIDITNPGYSKFRSTDANVHGQNPGENVPFQRCLEMESSRPPSTASSHSRLKSDSSISYNPALSASDLGQSNDSRPQLLTVGSSGSLFTGRNNSLAGQGAPAIERSAKPKGYAFNSPWGGKCEFATGSTGSTLKCKHTPPVVGASIFPTSAVVSELRFNLPHVSRSKKKLGTDSATRSRANSYSAQAPSIQRQGPDFDDLEKLDLTLGQESAGGGFGGKHAKLGKLVLEDEGLKMMDLLVAANMSLWWRAYERTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0X0</accession>
    <name>A0A6A6P0X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fimbrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0X0"/>
    <dbReference type="OrthoDB" id="431378at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032432">
        <property type="term" value="C:actin filament bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051639">
        <property type="term" value="P:actin filament network formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110009">
        <property type="term" value="P:formin-nucleated actin cable organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21294">
        <property type="entry name" value="CH_FIMB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21297">
        <property type="entry name" value="CH_FIMB_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21300">
        <property type="entry name" value="CH_FIMB_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21303">
        <property type="entry name" value="CH_FIMB_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000042">
        <property type="entry name" value="Fimbrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000010">
        <property type="entry name" value="Plastin-3 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000016">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000027">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00019">
        <property type="entry name" value="ACTININ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="141"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="290"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="414"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="539"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="650" mass="72828" checksum="C849A74C834148F2" modified="2020-06-17" version="1">MNIIKLQRKYPQFQQDEIFGLQDAFRRLDVDDKGYLDEATVIKSTQNSERQPYDVVRQALKEVELDSSRRVELEDYVDLISKLRQSSPAQKRMSTGPSRPRAVSGAGGMPTSPTHGHKGSYGGGRIQVQGSSANVTHTINEDERTEFTRHINAVLAGDPDIGHRLPFPTDTFEMFDECKDGLVLAKLINDSVPDTIDERVLNRPGGKIKNLNAFHMTENNNIVIESAKGIGCSVVNIGSGDIIEVREHLILGLIWQIIRRGLLGKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKNAKWHRTVSNFSTDVKDGENYTVLLNQLAPDMCSRGPLQTRDLLQRAEQVLDNADKLECRKFLTPTSLVAGNPKLNLAFVANLFNTHPGLDPITEEEKADIEDFDAEGEREARVFTLWLNSLDVQPTVVSFFDDLRDGTILLQAYDKVIPGSVNWRHVNKPPAHGGELMRFKALENTNYAVELGKQNAFSLPGIQGADITDGQRTLTLGLVWQLMRKDIVSTLGQLARRLGKREIADADMVKWANDTSRKGGRSSSIRSFKDSSLGSGIFLLDVLNGMKSSYVDYDLVAPGRTDEEAYMNAKLAISIARKMGATIWLVPEDICQVRSRLITSFIGSLMATAERMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P122</accession>
    <name>A0A6A6P122_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytosolic large ribosomal subunit protein L30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_344489</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P122"/>
    <dbReference type="OrthoDB" id="1928736at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00481">
        <property type="entry name" value="Ribosomal_eL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000231">
        <property type="entry name" value="Ribosomal_eL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="12"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="11722" checksum="78C15D93688DD392" modified="2020-06-17" version="1">MAPKKTKKTADSINSRLALVMKSGKVTLGYKSTLKSLRSGKAKLVIIAGNTPPLRKSELEYYSMLAKTNVHHFQGNNIELGTACGKLFRCSTMAILDAGDSDILSTSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P140</accession>
    <name>A0A6A6P140_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Imidazole glycerol phosphate synthase hisHF</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Glutaminase</fullName>
                <ecNumber evidence="12">3.5.1.2</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">Cyclase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_31216</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">In the C-terminal section; belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="12"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P140"/>
    <dbReference type="OrthoDB" id="10254903at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000094">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000039">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014640">
        <property type="entry name" value="IGPS_HisHF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036936">
        <property type="entry name" value="IGPS_HisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 12 15" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="16">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="362"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="400"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="472"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="498"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="521"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2457676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="59505" checksum="EFBC8DEE0148FC76" modified="2020-06-17" version="1">MPTVHLLDYVAGNVRSLVNAIEKLGWTVDWIKSPEEVSAAEKLILPGVGHFGYCVSQFAKAGYTEPIIAHIRAGKPFMGICVGLQALFESSEEDLSAAGFGVIPGRLDRFGDKDKSVPHIGWNSASTSSGDHVAGDSLYGLRPDSKYYYVHSYAMPYREGELEKDGWAVATAKYGDEEFVGAVARDNVFATQFHPEKSGAAGLGVIKAFLEGRKREALPSAPSLASAKLGLTRRVIACLDVRTNDQGDLVVTKGDQYDVREKGGVSAGGAVRNLGKPVDMARKYYEQGADEVTFLNITSFRNCPVADLPMLEILRRTSETVFVPLTIGGGIRDTVDTDGTRISALDIATLYFKSGADKVSIGSDAVTAAEEFYARGKTLAGTTAIETISAAYGIQAVVVSVDPKRVYVSSPSDTAHHTIKTAFLGPKDEEYCWYQCTTKGGREGRDFDVWQLVTAVEAMGAGEVLLNCIDKDGTNSGYDLELINDVKAAIRIPVIASSGAGNPAHFAEVFEKTSTDAALGAGMFHRGEYTVRQVKDYLQEQGLLVRQFEDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P170</accession>
    <name>A0A6A6P170_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_274175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P170"/>
    <dbReference type="OrthoDB" id="288942at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="24929" checksum="E13175A140538651" modified="2020-06-17" version="1" fragment="single">SHPQTQSPLFGVIPAEIRNLIYEFTLAQAEDGEHYPPNAYYYRPGYRRRGRVHAQLLLTCRRVYGETHGLPMRLATHPFWHSRGPPHAYRLKLLNFLRLTPKNLRDLEHVQFFTQLWWLEQGKLSADYLNQPRFQPRRITITIRHSDWWYWEKDHALKIEDAWVDRFRGPATLRLLTMEFETIERKAGQLDNIVAKQVPKWKFKRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1C7</accession>
    <name>A0A6A6P1C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1C7"/>
    <dbReference type="OrthoDB" id="552755at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="47809" checksum="2B35C756E939A835" modified="2020-06-17" version="1">MSGSEASADRSSPTGALAPDAMIEGALRGAVAKLFAESRFEDLTVKRVRRTVEEELQLGTDFLKTDKNWGQKSKDVIADEVSAQESKKEGEKDESPPPAPPKSKSKTAPAVKKRKEPQSEQPAKRTMKRASPQSEQQTAPKRRKVSLESELGLNVSEDEEKESAQADGAKENEANEEEVVKKPKAKAKPRLPAKKGQRGRPKKKAVSADKEEEEAEEAEKDKEINLDNGDGSDAVADVGKEYKQGETSHLEKEASPTKATVNETKDDDSSSLSSVIDETPPPKRRKKKEKPDAKLAGKQTKKRASKAKDETNVDPNDAEIKRLQGWLVKCGIRKMWWRELQPYDTPRAKINHLKAMLKDAGMDGRYSIEKARQIKERRELAADLEAVQEGNKRWGHSESEEEDPGKPKRRLARGLKELAFLNDDDGEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P263</accession>
    <name>A0A6A6P263_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HGH1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_363467</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HGH1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P263"/>
    <dbReference type="OrthoDB" id="338814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007206">
        <property type="entry name" value="Protein_HGH1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04064">
        <property type="entry name" value="DUF384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="4">
        <location>
            <begin position="94"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HGH1 C-terminal" evidence="5">
        <location>
            <begin position="292"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="40655" checksum="4A967EF805BE777E" modified="2020-06-17" version="1">MPSELEELVEFLHHGNTQIRQAAAEHLVGYSKAQPSVFKTGQLTPVKDLKLLVRDYPPIAKNALTILINISEDKEVLENLARDDAFVETLLSRITNPAEPNANDAAMLLANLAKSDSIQRLLALDRGSAPPPSLSRSRNAMDQLLACFVRGADGRFNPAADYDYLAYLFADVAKFERGRAYLVTPRGAGEEEEAVMPVTKLMVFTEHGSAVRRRGVASAMKNVAFAVGAHGRLVAGEADGGANLLPYLLLPLMGGEDYTDDDVEGMLDEVQLLPPDKEREPDADIVKTHLETLLLLTTTREVREVLRRVRVYPIVRETHLRVEDEGVREGCDRIVQMIMRDEEGEGSEMPKEVEEGEDEDEQIIDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P270</accession>
    <name>A0A6A6P270_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_390686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P270"/>
    <dbReference type="OrthoDB" id="2157498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029164">
        <property type="entry name" value="PIG-Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39400:SF1">
        <property type="entry name" value="PIG-P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39400">
        <property type="entry name" value="YALI0E29227P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15159">
        <property type="entry name" value="PIG-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="516"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="603" mass="60583" checksum="44B35461DC60B327" modified="2020-06-17" version="1">MENGQHRAAPTSPTATTTGSSVIPRRRSSSSSSRAHKRTLSGSILARLPFLRTSFDDADADAAQQGEEEAEVATAGAERSPDEAGGNGGLGQGSGSGQSRYQHQQHQRRGGGARPSMGRREAAAAGGAGGGAMAQSSGRSRKGSLRKRAMMSSTTGKMMMMQRRDSSTASTPTPAPTSASPASASAGASALPAASPVDGDSDGKDAEDDTEEDDADDDDRTPRRFSYEPDSSSPTTNSTSPSVSASSSSLWPPSPATLKALTLSPGALATAASAAAASKPRSSSSSSSSSSVDRIPHASPGSPLRSPGDEAAAPLYASTATTSDDDNTSASASSLGGIASGRESDGASKDSASSVVEAVAASPSSPPYFPLQAPSAMGSSLQRRRSATKSQNASGGGSNGGGSADAGKGGGQGAASPEGTSGAPAAGAGGAKAAGAGAAGAGAARPRQTSPLALPPAAEGDVPLLPGSSASAAARAAAAAAHHFNHHLHHHHHAHPQQLSSGTDQDDGWDYGETEWWGWVVLAVTWVVFVVGMGSCLGVWSWAWDVGETPYAPPELEDDATLPIVGYYPALIVMTAVMAWVWVVVAWVGMKYFRHAKVVGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Q7</accession>
    <name>A0A6A6P2Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_371156</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Q7"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025369148" description="DOMON domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="10">
        <location>
            <begin position="58"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="414"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="481" mass="51627" checksum="B046413BF380D14B" modified="2020-06-17" version="1">MLGFIRSLVLLFVYATSIAWAADASSGIVGRQDDDDNSTAPVSTFLYKASDYDEDNWANFTFALTVGRDSGDMWFKMMGPSMYSWMAVGTGNQMAGSMMFIAYADGDDDDITLSVRRATGHNEPSYDSNIDFELLDGSEIINGSYVINGRCKSCADSGKLDLDSTEFPFIFAFGPSGFAINSGSSSAGIRRHSAYGKFKLDLKAATTDDDDATVPTLEDTLDTNNIGTSLKEDDKAELPSRFHALVMCGSFVVLFPIGVLILRVLDRVMLHGIFQGIALLVVCAGVGVGIWISKLYNKSKSFSSGHQVYGLIVFVLLFIQWGLGFVHHLLYKKHQRPTILGKIHLYCGPGILVMGLVNGAIGFRFAGSNRRVITYCIVVVAMLLIVGGVLFLQRRKKARKARYMGAPGVPGGPVGVPPPYGGPGEPAGGSSSFGGGLASRFGLGAGHRSTSSQSDIALNRVPSQDPPPYNTGPAQEPRSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P380</accession>
    <name>A0A6A6P380_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.216</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">tRNA 2,2-dimethylguanosine-26 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA(guanine-26,N(2)-N(2)) methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA(m(2,2)G26)dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_343151</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P380"/>
    <dbReference type="OrthoDB" id="6349953at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.70:FF:000001">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 12" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="111"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="656"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00082896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00083299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2457923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="730" mass="81130" checksum="40A06CDA79F5446F" modified="2020-06-17" version="1">MGSSGSQSPTIAVNSPIPLSEDPVAVDSPPKADQLVQHNEAIYKTVKEGLAYILINPDARLSVDPNAGKQGGRQASEQAVFYNEIQQFNRDLSVLAIRAYGEHVVAERKEKIEKNKQRQREVETKRARKQKQAEQRTEEPKAKHVDEASTPAGEENEMHDQRAKPKRDLHSQEYENMHGIKRLKTESVAKGDQIETNIAVAAITSAPTGKDLEQHSKPKQVRFTILDALSATGLRALRYAHELPFVTSVTANDLSAKAVRSIQLNVEHNRLEDKIRVNHANALAHMYEIATFQGPAEPEDWKHRYNVIDLDPYGTAVPFLDAALQSVEDNGLLCVTCTDAGVWASAGYLEKSFSLYGGLPMKGLHSHEGGLRLILHAIATSAARYGIAIEPLLSLSIDFYARVFVRVRRSPADVKFLAGKTMQVYNCDQGCGAWTTQFMAKNTPVEGRKGKFYKHSYAQAPTTSPHCMHCGFKTHLAGPMWGGPLHNPIFIQKILSYLPDLDPTTYPTLDRLEGMLQTAADELTLIPAMSIKPKIPSASNVNPTTTSPATIDGGLRPYLDRSDPGIADPHPFFISPSALAKVLHCSAPSVDSLKGALRHMDYKATRTHCKPGMVKTTAPWGIIWEVMRQWVEQKAPIKEGAIKSGTAGWRIMRASNRPTHPYRSDQPPSPVHEADEDQVPDPIIVENPERRREKLNIVFDEELGKDKERKRLVRYQLNPRANWGPMTRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3K0</accession>
    <name>A0A6A6P3K0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_363258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3K0"/>
    <dbReference type="OrthoDB" id="1875589at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000030">
        <property type="entry name" value="60S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL14" evidence="7">
        <location>
            <begin position="57"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="145" mass="16309" checksum="341E5F305EECC509" modified="2020-06-17" version="1">MGDADVTACNWKLVEVGRVVLFAKGPYEGLLAAVVEIIDHKRVLVDGPSSDPAKVVPRHAIRLADVTLTPIVVEKLPRAARNGKVRKEWEASKVEESWNNTAWAKNRASVMKRRNLNDFERFKLMRLKKMQSFEVKKAMAKAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4E7</accession>
    <name>A0A6A6P4E7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Deoxyhypusine hydroxylase</fullName>
            <shortName evidence="10">DOHH</shortName>
            <ecNumber evidence="10">1.14.99.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Deoxyhypusine dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Deoxyhypusine monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LIA1</name>
        <name evidence="12" type="ORF">BDY21DRAFT_283028</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:14101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="Rhea" id="RHEA-COMP:12592"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="ChEBI" id="CHEBI:91175"/>
            <dbReference type="EC" id="1.14.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="10">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the deoxyhypusine hydroxylase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.29" evidence="10"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4E7"/>
    <dbReference type="OrthoDB" id="421002at2759"/>
    <dbReference type="UniPathway" id="UPA00354"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019135">
        <property type="term" value="F:deoxyhypusine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03101">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027517">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="11">
        <location>
            <begin position="248"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="330" mass="35939" checksum="AB137A62286A9941" modified="2020-06-17" version="1">MGPNDATIASLREILISENAPLALRFRALFSLKHIASLHPQTPQTQPAIDAVAAAFTSPSALLKHELAYCLGQTRHTALAAPHLRKVLEDRAEDAMCRHEAAEALGALGDEGSLDMLKKCRDDAGEEVVVKETCDIAVDRIEWEHGAGASEKLKKSNFASIDPAPPLPEQTSNVQDSIPNLEKTLLDTSLPLFRRYRAMFALRDLCSPPDLPSAIPAIQALARGFRDSSALFRHEIAFVFGQLSHPASIPSLVDVLSNKREAGMVRHEAAEALGSLGEEEGVENILRRFLNDDDEVVRESVVVALDMAEFERKGDLEYSIIPEAGKPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4H3</accession>
    <name>A0A6A6P4H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_339227</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4H3"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000006">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="8">
        <location>
            <begin position="31"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="17289" checksum="62B0EC0457BE1E98" modified="2020-06-17" version="1" fragment="single">MLGAPDASVPRVTAALSLLGRRVLHLGPPTSGIKAKLANNYLLAVNNIATAEAMRMGVAWGLDPAKLADLINASTGRCWPSEVNNPVPGVVEGAPAGRGYEGGFGVALMRKDLRLAVEAAVAAGVKARMGEGAREVYEEVVRGGDAGKDFSVVYRYLGGEETGREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P560</accession>
    <name>A0A6A6P560_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_199384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P560"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="323" mass="35580" checksum="63B36F1C11E70290" modified="2020-06-17" version="1">MEGTPPRGQPLSPTPRPPEQTLNFVCPPPAYSRSSSPGRQARFHIAELEPHHGGPNQEANIENYYKDFRVEVADITEKERPNSRTPLRIEIPKQPSRVITQPRPFLLDNGSVVPREQVAPRWPAIVRRVVQIFVFIFSIIILALMGHSLVLFESARSTLIPGGPHGMQQAWPVNAALEPNYLLVGVALASILTTAFSLILSLRQKLNSPMTVRDAYSISVTLFLLAGWVAGTAVLGQFRKTNGDSLICWACDKADAPVGSIIPYGSVCAEQTASVYIGALISILETLFLGTFAFTFLWTRRQAVPSSRNHFPLKSWATNRACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5T7</accession>
    <name>A0A6A6P5T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_282503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5T7"/>
    <dbReference type="OrthoDB" id="5379086at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21924" checksum="CA723F5545F02DC9" modified="2020-06-17" version="1">MHLEHEELGRKYVNSETMFGDDIKDIPRSNFWVSEDGYAWDMEELAQAIEANSGVMRQPLSKHMFSTADVRAIVQHPIGKRLAALSIEQGQMAKGVRRSTIDQLDGLGKTLMADQSSDQLTSRHAIDEFLAYVATLPVAEQQVLDTLRVPAMDSHTNREYDMSIGEAVQDAKGNRVCLHKTGDFIGQAVKYLRSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6G3</accession>
    <name>A0A6A6P6G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPIN90/Ldb17 leucine-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_317723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6G3"/>
    <dbReference type="OrthoDB" id="445362at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN90/Ldb17 leucine-rich" evidence="2">
        <location>
            <begin position="186"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="464" mass="52744" checksum="F9599C25B9089FAE" modified="2020-06-17" version="1">MELDVSYSLENEQQFWDELEDIVTKKCDSHEVIDNALRTYLHFTTNFRDQYLQSEDDVLRCTFKLLEACLYADHKEYVRRQLVYCLLQEDDPPTLHIITAFLLFDGIHHDETFEMMQTEGAFPRLIELIQSPNLNSDFRLHRLLLRLLYEMSRIQPLTWEDLVAVDDAFVLHLFQIIEQLSDDVNDPYHYPVIRVLLVLNEQYMVMSTASSQPLTNRVIKALSTHGHLYKTFGENLILLLNRESETSLQLLILKLLYLLFQSPSTAEYFYTNDLHVLLDVVVRNLLDLPADSAPATALRHTYLRVLHPLLANSQIAKEGAHYKRDEVRKLLALLTDEGKLSGIHFAPVDDTTARLVRRCEAVAWLRDPKEPIADKATPQKDRARRQMLGMSVHDARQTGSSLSMAEMAAQTERPGVVAPSRGERGRDKAGGETEGEKGERAEGDVVAMVGTGTGVTAARNGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6G8</accession>
    <name>A0A6A6P6G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_282041</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6G8"/>
    <dbReference type="OrthoDB" id="10254238at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="30"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2459580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="14885" checksum="07E4C333D0FD661C" modified="2020-06-17" version="1">MPPKATKTPTTAGKAPAGKAPAEKKEAGKKTAAPSGEKKKRTKSRKETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6I0</accession>
    <name>A0A6A6P6I0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_199965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6I0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19095" checksum="E61C7C6BB3999525" modified="2020-06-17" version="1">MDQQILTKVVNSMSMRIEGGDPRQMAGILSIRIKKMEGFGRIQAQLIVETRQEGRRIYIYSLPGAQPMEPPSLAGGSESPPHAGRWVCGEWALRGKAVTRASSVACPDKMRSIWLARPAGQKGRTQQPWALGRRSEPCPSVGTKKREEEERGDLERRNACGDGRWPEHSLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R1</accession>
    <name>A0A6A6P6R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_362597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6R1"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="409" mass="46199" checksum="E3FC84D34E009AD5" modified="2020-06-17" version="1">MRFGQLVIGSPGAGKSTYCDGMHQFMGAIGRKCSIVNLDPANDRTSYPCALDVRDLVTLDEIMEAEDLGPNGGILYALEELEHNFEWLEQGLKELEDDYILFDCPGQVELFTHHGSLRNMFLRLEKLGYRLVVVALTDSYVLTRPSLYISALLLALRSMLQLDLPHINVLTKIDNLSNYPELPFNLDFYTDVQDLRYLLPHLEPEQPGRDNKASRKKASRDGQGSEDEDEDEDEIDHPKSKFAALNRAIIQLVEDFALVGFTPLAIEDRSMMMVLLRQIDRAGGYAFGGEGANDTVWQIAMRENEITMDVRDVQERWIDRREEYDEEERKLWDEESKLMKEEGSAGTRTATSEEDGGIGLGGVGDNTSPGTNDLDIASEDDEDIVAIKEWERKRRKDVETGGIKIVRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R8</accession>
    <name>A0A6A6P6R8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">KH domain RNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_282022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6R8"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22439">
        <property type="entry name" value="KH-I_PCBP_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="121"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="204"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="415"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="313"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="378"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="491" mass="51215" checksum="82E0E2E6E2DC2221" modified="2020-06-17" version="1">MSASPTPTSAPSQKRPLEEPSSPSGPGDQPDAKRPALDKVAKEDEANNAQAATQPADNAGAGIPSTENGNKDVHGDTVVPDAPAAAGIAILETQPIQSTASSSNPRGASQGAAGPPQDETNWLHVRAIISSAEAATVIGKGGENVTQIRRLSGARCTVSDYSRGAVERILTVSGQVDAVAKAFGLIIRTLNNEPLEASSTPQSKTYPLRLLIPHILIGSIIGKSGVRIREIQEASGARLNASESCLPLSSERSLVILGVADAVHIATYYVGRTLVDQLTERFGGPAASAYATRSGGPAGVVPGGMQVVPYVPQPAGGQWGHPDNFRKHTNTTQRTPANPYGVPYLHGQPPQQQAQAPIHYGAGSPNRYTGAGPHQPQQYGAHPQATAAAAQHGGAVPHAAGQAGAQPMQGVMPGQPMTQQIFIPNDMVGAIIGKGGAKINEIRQFSGSVIKINEPQDNSNERLVTITGTQECNQIALYMLYSRLESEKHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P725</accession>
    <name>A0A6A6P725_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CPSF A subunit region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_281417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="12"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="562"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="1034"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="434"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="579"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1275"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="579"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1275"/>
            <end position="1290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1438" mass="152607" checksum="244B36B133AD8BE1" modified="2020-06-17" version="1">MQCYSELTPPTAVSHAVSLAFVAPGAANLVVAKSSLLQLFELRPASAAASAAASAAASDDASRLVLVAECPLAGTVTGLARVKATETRSGGDALLVAARDAKLSLLEWDPELHQIATVSIHYYEGEDGGLAGGCPWDPPADDAPSLLVADPGSRCAALKFGARRLAILPFRQPGDDDLVGDAEGEGEETRRRETATAPRTPYRASFVLPLTALDPALTHPVHLAFLHEYREPTFGILSAPRAPSQALLRERRDPLSFSVFTLDLEQRASTPLLTVSGLPQDIFRVVALPLPIGGALLMGCNELVHVDQSGKTSAVAVNEFARHYSAFPMADQTDLGLRLEGSVVEPLDQETGDVLLVLRDGSLAVVSFRRDGRSVSGMSLDRVDSDRGGRCVQAGPASCAVKVSRTSLFVGSEVAPSLLLGWTRRQSQQLARKRSRAEVLADPDADADTALSDADEDFMDDDYDDDLYDGGGPARVSGSAAAPKTGEQAATGRHSFRVHDFMLSLAPLRDVTLGATPPRAPDVTRAGDETVHAPLGLVAATGTGAAGGLALLHGRVEPVVLYETAMPSARALWSVRTNAAAQGEPAAAGSTGRRGSKRRRGSSTPDAGTDASYDQYLVVSREGQAGGEGGSAVYRVEGEAAVSEEVEAGEFEKGQETVEMGSLANGARVVQVLRGEVRSYDSDLSLSQILPMEDEDTGAEPKILSASFADPHLLILRDDSSAVIFRADGGGELEEVERGEALKSSKWISGCLYASAATNGETLACLLNAERGLHIYKLPSLGEPAHVAEGLRFLPPQLDEGYAPRRAGARAPIAEIMLADVGDRVAKAPHLIVRTEDDDLSIYEAYHHPSKEERNGSFCDGLRWAKLPQPHVALSPPITSQDGTPAAEPQSHLLRAFADIGGYCTVLQAGASPGFVLKEASSTPKVLCLRGRAVRSLTTYHAPGCRSGFAYIDVHDTLRICQLPPSTRYGDLGMAVRIIPLGEEVQALCHHPRRDAYILGTIQQVPFKLPEDDYHHEWAREATEFLPSVSQGLVRLVVPDSWTAIDTVVLDPGETIQAVRMLNLEVSETTHDRKPLIAVGTALVRGEDLAARGRIYIFEVITVVPEPTRPETNRRLKLIVKEEVKGAVTALSEIGSQGFLLVAQGQKAMVRGLKEDGTLLPVAFMDLQCHVSVAKELASTGMVIIGDVARGLWLVGYTEEPYKLMLFGKGGHVGVIAAEFLPFQRQLFILVADAECNIHVLQYDPEHPKSLSGQRLLHKSTFHTGHFPTSMTLLPSSLPPSSFSEPSDPDAMAIDSNANGAPDSDQQNDKPTHVLLASQSGALAVLTPLSEDPYRRLSSLATYLTNTLDHAAGLNPRGFRARNPASTATAAFGVGGGAGGAGGKGLVVDGCVVRRFGELGSQKRAEAAAKVVGGGVEGEWVLRRELGCVVGGAGLGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7C2</accession>
    <name>A0A6A6P7C2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_268515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7C2"/>
    <dbReference type="OrthoDB" id="3352776at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17090" checksum="7F557A264560B188" modified="2020-06-17" version="1" fragment="single">LLRTRTASFLSALVSPSFDPTTFLTTHFTPSTPRITEHGPPWAAASRLPFLGHTFAGLDGCLTYFLLLAATLETRWGEGTFPAGEDGVVVDAGASADGDAEEGEGGPRGVVCVVGKAQFASKRTGKAWAESFIYRLSGFDDEGRVGHWEIWADPLSAWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7D6</accession>
    <name>A0A6A6P7D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_338870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7D6"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000010">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF29">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52049">
        <property type="entry name" value="ULD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="43"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="418" mass="47301" checksum="EBEB184BDD6E13B5" modified="2020-06-17" version="1">MAQASKRRRVGENNEPNSTANDVVFSKDLLSPITAEERRKWQGFCEIDSDPAIFNVMLKEFGVHGVRVQEVLGLDPELLDMLPKPVYGLIFLFRYREDGSENQEASCPDHVWFANQLTGNACATVALLNLVNNISEAELGECLRSFRDFTKEFTPAQRGYQLVNFEFIKNIHNSFARKMDMMNIDLGMKNNYTDRKRSRKDDNADEDENDQAFHFIAFVPINGEVWQLDGLDRQPRNLGAYLEGNWLGSVAPLLVDKMAAYEQEEIEFNLMSLVKDPVTTLREELAANICSLRKVEKTLDDTDAEWKNFTTDSDDDVVRGPDLALGVFASLIEDSNIPAAVEKKVAIDESMSGLLDVRHDLINQQAKVKIAIRDEAESARADTRKALERRCDFGPMIHKWVGYLAENGVLRELVETVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7J0</accession>
    <name>A0A6A6P7J0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_177586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7J0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="17466" checksum="0DA6780A27E72A65" modified="2020-06-17" version="1">MCVRCPACRLSSDITLPVFSLSPSPSLRLSRRLFFFFSHYRLRASIGHVPLPAEALSFLSHQGGPTRHCVPRQQASGGPRRGRAGSGCETPLDGAAVAQEVRGCSAELWVDGKDAESDGARESQSGASRAAPPPSQPGGCASPAMPSWAPGSARPWRPALTACPACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P890</accession>
    <name>A0A6A6P890_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flavin-containing amine oxidoreductase-domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_337060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P890"/>
    <dbReference type="OrthoDB" id="9982100at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000064">
        <property type="entry name" value="Lysine-specific histone demethylase 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="6">
        <location>
            <begin position="289"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="1046"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="1046"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="114"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="986"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="997"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1149" mass="128135" checksum="AEE788DADC70F0A4" modified="2020-06-17" version="1">MQSRPRNAHRHAYRSPPCCVNRAAASHFCPSSERAATWAQVVPESLGMFNIDPESTTNGDALDEQFLFSNSHDILDGPFDSDAMAHDLDLKGSNIEHSTLTGFDNLAMYEQYNESGPSSVHFGDLRDPSEREESHPSGRDEADVAVSDHSAVHFQETSQSDNAREVPSSGTPDVAPGNGKKRTVNGDERPASRSAAQFTIAPEVHRVTKYVSYNAPKKRPEDPRSVTSPGGPHHTPERQEKFARKVSQQSQHSASSYSPSNPQTRKKHGFRARSSIPSSLSWEEFARQCVLAAYSSRLNPFALHPDEYQMLREHITRAQVTIYLNIRNAILRLWTRNPLVSVSEVEAAGCARDNRYFNLALFAYQWLQRRGYINFGCVYIPTPSNQAPERPFKEKRKTVVIVGAGMSGLGCARQLEGFFGHYAERWADLGEQPPKIIVLEGRNRIGGRIYSYHLGKQDTSNLPPGSRSTAEMGAHFVTGFEHGNPMNILIRGQLGLHYHRLKDRTPLYDYDGSLADVARDGLVEKLWNDILERASAYRNKPKTNETVEGDRRLIQYGRDPSSDQGDVLAALEKAGQPATINLNRTGSPLSGVTDHVGAAGLEKLSGRAYLTVGSTGKESASDAAKEMGWELRPGIEDGKTVNFDEIAQSSAYPNLGDTMDEGIRQYQTMLELTPLDMRLLNWHHANLEYANAINVNQLSLGGWDQDIGNEFEGEHCQIIGGYQQVPRGLWKCPKPLDIRFNSKVTEIRRSATSDQKGDNLTVVCEDGETIAADHVVVTTPLGVLKSNTINFQPPLPEWKIGAIERLGFGVLNKVILVFEKPFWNVERDMFGFLNDSEFSYSLDQRDYASRRGRFYLFLNCFKTCGRPMLIALMAGDAAKDVEKSDDESLLNEVMENLTRMFVHARVPRPSETIVTRWRHDQYARGSYSYVAPLTQAGDYDTMAQPVGRIHFAGEATCGTHPATVHGAYLSGLRAASEVIEAMAGPIQTPQPLVPPKTKLESAGKRKMEETSSGSKRRSKSVPDEDREARILEAVIGEIGERPTKPGKSGINPFLLFTKDHWHECKARCEEERQSKGQKGDTKPTKNEIRVAIGKMWRNASDEVKRPYLEQTQAAKQLTAAGNAEYKERAANWDKEAARIRREFVEKQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8G8</accession>
    <name>A0A6A6P8G8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_177216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8G8"/>
    <dbReference type="OrthoDB" id="1162399at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04462">
        <property type="entry name" value="S1_RNAPII_Rpb7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="81"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="21401" checksum="839F81B49E0AAE03" modified="2020-06-17" version="1">MFFLHELERTITLHPSFFGPRIDTYIGEKLLQDVEGINTGNYYVVCVLDSFDLSEGRVIPGTGSAEYTVHFRAVVWRPFKGEILDGIVAQVVESGIFVDVGPLSCFVAKSVCLVSELNTTKRDFLTLQKMIPSDIKYDGNSTPPQWTDNADQVIEKGSHIRIKIKGIRVEVDEMFAIATIKEDYLGPLPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8J1</accession>
    <name>A0A6A6P8J1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aquaporin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_269585</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8J1"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="280" mass="29335" checksum="AB339D2C86564395" modified="2020-06-17" version="1" fragment="single">RLRGLGWLPARARAHLVAALGEFAGTCLFLSFAFAGTHVANAAAAGQIEAAGGSEDADAARYPNTPVLLYISLAFGFSLAVNAWVFMRISGGLFNPAVTLGMCLIGAVPWLRGLIDTLAQIAGAIAASALVLGLFPGTLAVRTTLHPSTSHVRGLLIEALLTAELVFAIFMLAAEKHKGTFLAPIGVGLCLFVCELAGVYYTGGSLNPARSFGPDVVLGTFDSYHWIYWAGPAIGAVAAVLFYRLVKVLEDETESQATDVDEKAAEPLREDKDPDTAGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8L7</accession>
    <name>A0A6A6P8L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative malate/L-lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_279900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH2/MDH2 oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8L7"/>
    <dbReference type="OrthoDB" id="7881616at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.60">
        <property type="entry name" value="Hypothetical oxidoreductase yiak, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043144">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_ah"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043143">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036111">
        <property type="entry name" value="Mal/L-sulfo/L-lacto_DH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003767">
        <property type="entry name" value="Malate/L-lactate_DH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11091:SF0">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11091">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02615">
        <property type="entry name" value="Ldh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89733">
        <property type="entry name" value="L-sulfolactate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="359" mass="37317" checksum="EEA6980F95BDEDB7" modified="2020-06-17" version="1">MTDSTEPAAPKIHIAASRAHDFVAAVLAANGVPADHASTVASCLVEADLRGHESHGINRLPSYVARLRSGAMSGAASPAVAPVTPCVGRVDAANCLGAVAARAAMAAAVDMAKGPAGIGLVGVRASNHFGMAAWVVQQAVDAGLLCLVFTNSSPALPPWGARDRLLGVSPIACGAPAGPRGRPFVLDMAPSVAARGKVYRAERRGEAIPEGWALDRDGAPTTDPARALEGVMLPVGGPKGSALAIMMDVFAGVLTGSAFAGHVASPYDASRPADVGHFFVALRPDLFVSANEFRDRMDYLYQRVVGAEKMQGVDRVYFPGEIELVTKEERERTGIPYVEAEIAALNEEARHVGVEPISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9D5</accession>
    <name>A0A6A6P9D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_315788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9D5"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052279">
        <property type="entry name" value="EngB_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46498">
        <property type="entry name" value="GTP-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46498:SF1">
        <property type="entry name" value="GTP-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EngB-type G" evidence="6">
        <location>
            <begin position="125"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="39763" checksum="89F9EAE83C9F09DF" modified="2020-06-17" version="1">MSTKLRRGTPSIAYVCESCISSLRTSQRTPTSPSQHLRRLTTASAQPESRSSPSSSALDNSSSSSSAPPTALPSPSSFTSPSINTYLTTSAPSASQLLLADRFFAAGNPRFLFSSPTYRDFPATPAPEVAFLGRSNVGKSSLLNGLLGRTKQRVAHVSKKPGRTRTMNAFLVGPGEGGVRDVVVGLDEKGRKKVRKEPWVGAGGGNVVVVDMPGYGKGSRKEWGEEIFKYLSKRDQLRRAFLLVDAEHGLKDSDTYILNGFRANGIPHEIVLSKADKILLPRPRMPSPEAWQRHLAHMRHASEKVYDGIVRLHGGRGMRLNAILACSGEKRDANGKLLGMDALRWAVLQAAGLGAAQLEQLLPRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA31</accession>
    <name>A0A6A6PA31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_131064</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA31"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019413">
        <property type="term" value="P:acetate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07091">
        <property type="entry name" value="ALDH_F1-2_Ald2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000001">
        <property type="entry name" value="Mitochondrial aldehyde dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="26"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="495" mass="54037" checksum="49237EC9AE4FCD96" modified="2020-06-17" version="1">MTSVTLKTPHSGEYQQPTGLFINNEWVKGVDGRTFEVINPSDETVICSVHEATEKDVDLAVAAARKAFEGDWRKVTPEDRGKLLVNLAQLFEKNVDLLAAVESLDNGKAISMSKVDVSMCAGTLRYYGGWADKIEGKVVDTAPDTFNYTKKEPIGVCGQIIPWNFPLLMWAWKIGPAIAAGNTVVMKTAEQTPLSALVACNFIKEAGFPPGVINNISGFGKIAGAAISSHMDIDKVAFTGSTVVGRQIMKAAAGSNLKKVTLELGGKSPNIVFDDADIDNAISWVNFGIYFNHGQCCCAGSRIYVQEGIYDKFLERFKERAQKNEVGDPFGPSTFQGPQVSQLQFDRIMSYINHGREEGAKIEIGGKRKGDKGYFIEPTIFSNVQENMKIMQEEIFGPVCAISKFKNKDEVIKLANNTTYGLAAAVHTSNLNTAIEVSNALRAGTVWVNTYNTLHHQLPFGGYKESGIGRELGEAALENYCQTKTVSIRLGDALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA81</accession>
    <name>A0A6A6PA81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HCO3 transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_369375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anion exchanger (TC 2.A.31) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA81"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046713">
        <property type="term" value="P:borate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.570:FF:000003">
        <property type="entry name" value="Anion exchange family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF38">
        <property type="entry name" value="ANION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="8">
        <location>
            <begin position="44"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="8">
        <location>
            <begin position="221"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="615" mass="69487" checksum="EFD851E7F4158245" modified="2020-06-17" version="1">MQQGTEPATVDESPGEYTLTREKTTGTTYDFDNARGWRKYRVLRPCLGMYHDVKRRLPFYWSDITDAWTYRTIASIIRMYFVNLLPALAYTLDMYRRTGEFFGVNEALFASALAAMVFSILGAQPLTIVGITGLISLFNYTIYDIIEIYDISIYPQFMCWTAIWAAIFHWLVAVWNICDYMRYVTDFSSQSFALYVGIIYIIKGVEEIVNEFTQYGSTPGFLTTLIAILYFGTVYGLEKLGSSTVFKPSIREVLADYSYVFATLFWVGFGHFPGRLKEAHISHVPTVGAFEPTQPRSWFIKFWEIDVKWVFVAIPFGFLIMLLFYYDHNVSSLTAQARQFPLKKPGGFHWDFFLLGCTTFVAGLLGLPMPNGLVPQAPVHTDSLTVYETELKVIKTEEGEGAEIRRPIVNATAVVEQRVSHFVMGLALIGTMTGPLLTVLSTMPAAVFCGVFFVVGWGSIETNGIVQKIIFVFSEKRFIHPDEPLHTVQKRKILLYVGLQLLGVLSCVAISQTIAAIGFPVLICALIPLRVYCLPKMFSAHELHVMDDLTADNKAVLASLGGAPLLPEVRMARERHARGEATGYLPHEEEEYGLERKYSERRRGVSRQRVGSVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAZ2</accession>
    <name>A0A6A6PAZ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_297795</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAZ2"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="348"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="11">
        <location>
            <begin position="512"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="86"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="484"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="59801" checksum="9B960273E50D1B50" modified="2020-06-17" version="1">MSQSYFSPEVVLLGSRPKTQVYIRSRHVERVLCRRLDEQRGEEYLVLWRKRSIPDPASAPASWHSVNELSRCLHLVQDYLNSCPKPSRKRINENRSPEVSDRRVAAKVRETSSPALSPAASASPSEPQPGSRDIKIFNGVLREIGGYIVAENSSNNDVVLFDATTLPTPDMVERATRTEATIAASRIRYEFTQRLRNISGPPIQLLNTFDESSPPLRFQFIDKCVIRDGVQRADPATLLGCTKCRPDMGQNIGCEYTLKCECLEYAAVDTARLSEEQRERYSLIQANGGEGDTSGMPKRFPYHSPFGNRAECLVPFYLESRHPIYECNVNCGCKGNCKTIVVQKGRQVRLQIFKTRDRGWGLKTLQDLKEGQFIDTYRGEIITDAEATRREEAATSRKDSYFYSLDKFADSQGLQPEDLYVIDGEYMGGPTRFMNHSCEPNCRQYTVSWNKNDFMIYEIAFFAIRPIRAGEELTFDYLDKDDIDESQSTSKSGQEKSSGDGGGAASTDASLKPVECRCGSKKCRKYLWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB03</accession>
    <name>A0A6A6PB03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB03"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16859" checksum="D4440143537ABCD8" modified="2020-06-17" version="1">MVHGYLGEDSALPAKILPQLVARDSRAVVHGRQVAVRDGIGVGGGGSGPARAEEGLAGVEGGIRKRRTLLELAGPLPFTSEEVYMTSKHTGVRGPVGSNGVLLHFLYKWPLRTGQTLLDLRLNTYLDLVIALQLYTRSRPLPDLHRRSRGIARLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBA8</accession>
    <name>A0A6A6PBA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit SPC19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Outer kinetochore protein SPC19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_280255</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC19 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBA8"/>
    <dbReference type="OrthoDB" id="3361333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013251">
        <property type="entry name" value="DASH_Spc19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08287">
        <property type="entry name" value="DASH_Spc19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="102"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="20742" checksum="DBB7A1A1BE6C92D6" modified="2020-06-17" version="1">MAGSLEGCVASLRSSMQLLDSSISILDSGVKDFPRLSRVLQTTRHFEIISEPELHAAQSALVSEIRPEVDALLGRVAAYLDKLERRERSLIAKYDLQAGRLSSSEERADKGAAATAKRQSEQRMRSLGGAGGAPGPEKNNPLAELKMKQLRQKKERLSYAVDRLTLQAQQRERQLRMSMAAPQQRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBC9</accession>
    <name>A0A6A6PBC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger protein-like protein zpr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_279678</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a protein folding chaperone for elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZPR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBC9"/>
    <dbReference type="OrthoDB" id="308464at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000002">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000003">
        <property type="entry name" value="Zinc finger protein zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="10">
        <location>
            <begin position="41"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="10">
        <location>
            <begin position="275"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="459"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="502" mass="55216" checksum="1AA38E07C1FC0BFD" modified="2020-06-17" version="1">MASANPSLAQDLFEDMGRKVAEASREGFGDGNSKVVEEIESLCMNCHDDGVTRLLLTRIPFFREIVIMSFSCPKCGFSNTEIQPAGEIQQRGARFALRADKSTDLNRQIVKSDTCTCKIEELDLEIPAGRGQLTNVEGLLAMVASDLEQKQDERKEVVPELWAKIEEIIKCLRAMASSESLPFTVTLDDPAGNSWIEPSPSDKGGKYSKHEYARTAEQNAALGLTVEADTTSTDETTTRPEYHAHAMVPELPPGVKTNNVDEEEIVENQVYSFPASCPGCTKPCVTNMKMVNIPHFKQVVLMSTVCEHCGYRSNEVKTGGEVPEKGRRITLEVRTSLDLGRDILKSESCAMNCPELSLAVEPGTMGGRFTTVEGLLTQVRDDLHSSIFDTNAPASEPIPPDAFTAGGDSMDAETRAKWAAFFGRLNSALKAETSFTVVLEDPLASSYVQSLVDDGRDEQIKVEDYDRTDEEEESLGLKDIKTEGYEESEARVEHEDGNKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBF1</accession>
    <name>A0A6A6PBF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBF1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="17741" checksum="A805D261989394ED" modified="2020-06-17" version="1">MPAGPLESRADAPPCLRRVIWAWSDMRAEPPAAGGGDGDEEDRKGAPEGAPRASSASPSMSPSSSSAGNAAATFDCPVSAFAAASHALKASSASSSLGIASSLSRIVLASAWALRSSSAARARSMGPVAAAAATLGTCAVDAFGGGLASFFWAGAAWGFEASRNRVEALAAVLDDRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBH0</accession>
    <name>A0A6A6PBH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_333334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBH0"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="25372" checksum="96EAB520ADF3758C" modified="2020-06-17" version="1">MSDDEAFESLEKEAKEFDKDAEIDRILKTFKLDAYAILDLQPGVPESDIKAVYRKKSLLIHPDKTKNPRAPDAFDLLKKAQTELLDEKHRARLDEVIADARRYLIRDRKLTVDSPELKTAAFGRDWREKTKQLLIEDEIRRRKQQRAQMQEEGRQQKKEEAEIEERKRKRDHEQAWEQTREKRIDSWRQFQKGQGTPVGEDGTKKKKKKMKTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM8</accession>
    <name>A0A6A6PBM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein get1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GET1</name>
        <name evidence="12" type="ORF">BDY21DRAFT_278454</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the WRB/GET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM8"/>
    <dbReference type="OrthoDB" id="69461at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.660:FF:000006">
        <property type="entry name" value="Protein GET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03113">
        <property type="entry name" value="Get1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028945">
        <property type="entry name" value="Get1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027538">
        <property type="entry name" value="Get1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650:SF1">
        <property type="entry name" value="GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650">
        <property type="entry name" value="TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04420">
        <property type="entry name" value="CHD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025540772" evidence="11">
        <location>
            <begin position="17"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="4"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="9">
        <location>
            <begin position="173"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="24462" checksum="25363764B581EAF6" modified="2020-06-17" version="1">MISLLLLVFLVQLTTQLFSSVGVATTNEIAWILYNKLPTKTSQSVQEQTKLQREILRMKKEMNAVSAQDEFARWARLRRQHDDVVAKYENISSSLSSTKTSFDRTVALLRWIATTGLRFLLQTYYQREPMFWIPAGWLPYYVEWILSFPRAPLGSVSIQVWSMACSSIITLVGEALVGVWSLATSKKSGMQSKGSARRAQAYGPSSSARQAAAKKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC29</accession>
    <name>A0A6A6PC29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar transporter chaperone 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_332449</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC29"/>
    <dbReference type="OrthoDB" id="2243669at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="13826" checksum="646340448AADF12D" modified="2020-06-17" version="1">MSTQPLLQTAPGKRIALPTRVEPKVFFANERTFLSWLNFTVILGGLAMGLLNFGDKVGRISAGLFTLVAVAAMIYALFTFHWRARSIRMRGQGGFDDRFGPTILAVALLAAVIVNFVLRVVGPKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC92</accession>
    <name>A0A6A6PC92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_403234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0507 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000443">
        <property type="entry name" value="Putative vps9 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="342"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="538"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1298"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1342" mass="148711" checksum="7C849022969671A7" modified="2020-06-17" version="1">MHPLNPFLRAFFRSTLPSQCSPPQHHILLVPTTEALFNGRDRESQASYADLAGSSEDFLASHVLRVPGGIPPGGQTKEGGTTFRDNRGKAKQYPTINGRSVIVKDTFVYSNKGFKTLNQAQLLNDIIYYPDTFDAQPWLVYYIAKPLIGVYETILIASPTAPGTPQASPTRSANGTNGATSSMPRKKEVKSFVDVLNLFPMIARQLEPGLERLFKEFGKELEKPLPERSKAKSPSIRSRRSNSGSSSENESAASLRSIGLMNGYRSRLSPELEEEEDAMRRALETAVTAAIDLFQMVDKQQLSLLGATTDLTGPLVERMIERYVAERVHDTILFPRVSMIWRSEDIELESRMRQMADVDISQVGIAMGHTRRGKQELALRLAKGVDAFKRMGVASSPQEMMEILLATQKAITTSDSSREEARTDVTSPVSDSRSEKQAETASITVNADTLVSLLLVVVIRAPVRHLHARLSYMRHFIFIDDVEAGEMGYALSTFEAVLSYLLRDSAGLRKASRRNRKLWQATKDGDVAEIRKILEPETEHFEGAIEDGENGAGPVEDGAVSSTSQQPRISFSNTSPTEIGNLDGSLDDRYDSIQDLSSGQEDQPLSHVFPFLRSPSPPLAPTLSSPEDQRPKMKKRVSVETRSLSISSGFSFKSRTDTLDSWVSDVEGDMAVETLARTQGPGGDSILMMAVENGQVGALRYLLGLRRYFSVKDVFEDANYDDTTLLSAAVQTGKQDIIETVLDFIVDNSENNDELSEYLARQDSNGRCVAHYLFNQPRLISRIGHLLPWKLKDKNGQTPLFALCRSYDHEEYRWMVEAALDAATRSQGDGQALHLDDHVDAKGNTLLHIVNDPPLARRLLYHSDSDANAANDKKFTPLMVASKYGRTDLVRTFFADPRVDLYARDMRGLTAVELAKDDEVRNRIDDLVLLTATNPADSGGRTTTVVRSFFVEDGSVRLILKSGAPSGNETITVTTCRRSVSDFEHLAKCLSIEHPASWLPQLTNFPSPFMIPSKPSRAILRDMQIQLDNFLKVLLTHPTFSTHEMVWEFFLVPDIELPMLAARTRKKAEARAERVREEYAPLLDVREVELFTSFALESVRGVHHATRSILRRVNRVRFEQADFADAANMLLGTATQTAGAFLPREHVTALDRFTRTLGQTEVSPMTSFYYGMHSIASTVSAILAALGRPAQLIGSMAASRKAMERHTLSLRRNDRWPLGLLDDTRHRMQREAADKVARSSAELESLARELRYTQQTVAGELAAWQEGRVRAGRAACRELARRMVVAEKARLESMKRAVRGLGLDVEGPSKKKKGMAQRKGPGDQNGDGGGGGGGGSSRASQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCK4</accession>
    <name>A0A6A6PCK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_314331</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCK4"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="559"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="81"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="210"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="440"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="751"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="880"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2461668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1279" mass="144835" checksum="5B1B78C3E24EF9F4" modified="2020-06-17" version="1">MGKLIRLELFNFKSYKGHHSLLFGDSYFTSIIGPNGSGKSNSMDAISFVLGIKSSHLRSSHLRDLVYRGRVLRTSKIHADGTATTLGDGEAPQTNGHTNGDAGHHSDDDEPTPTQTRSQRDDPQTAWVMAVYEDDAGDEQRWKRTITATGASEYRINNRLVSAKQYNDALEAENILIKARNFLVFQGDVEAIANQAPKDLTRLIEQISGSLEYKAEYDRLKIEAEKAADDQTFKLNQRRAINSEIKQYQEQKREAENYARKADERDQAIIKHVLWKLFHFQRVMDESGAEIQRHQEELKEYRRNVEKYEQRLEETRRDHAKVNQSVSKVERSIKAKEREIEEKENSLVPIDEKISISKGKIEKYAARVAELSKERDDQNRQVEHLQKSLDTVQKAQAKWEQEWTQLMQREGRELSEADLQEYNRLRGEVNKRTAADQIRVDNLTRQIKTDEETVNSLLSKVETSQAQVQKLDEEMRELKERRANVNSLVKETQKEIDAKKKAFNKAQSERLRKEQLQTELNERLQEILKQLAEADNGRRESEKEQRARETVAAMKRIFPGVRGRVHELCKPKQKRYETAVSTVLGRHFDAIVVDTEKTAKDCIGYLRDQRAGQATFIPLDTIQVKAVNSSLKAAHRGVRLAIDTIEYDSVVERAMSYACGNSVVCDTLDIARDLCYEKRVDAKAVTLDGVVIHKGGLITGGRGPNDARNARRWEDAEVEALRHQKDKIMADLNALPKSTRRVEEETLQGELAGLEQRLHYAHEESRALERNLASKKSERDHAARQLAEARPKHAEHAARLSSLRDELKGHAERVAEAEDNVFADFCARLGYADIRAYEARQGSAQQEHAQKKLQFTTQRSRLENQLSFERQRANGTAERVASLEATARRDEELLERLGEQKEDLQAELDALREELETLAGQLDAQKEKLSARAERVNEARRELARRSRNVEGALKAVAELEAEVQRAAAGRYALLRKCKIDEVKVPLVEGSATLDSLPLDNLLRQDPDAMDVDGEEEEKDGIAAQAVEVQDYGIEVDFDGLDEELKEDPSPKAEEPLLETISTLSAQLDKISPNLRAIERLSGVEGRLKTAEKDFEGSRRAARRARADFEDVREKRLELFNKAFSHISEQIGGVYKDLTRSAAFPLGGQAHLDTEDDEEPYNAGVKYHAMPPLKRFRDMEHLSGGEKTIAALALLFAIHSFQPSPFFVLDEVDAALDAVNVAKVAGYVKEHAGPGMQFIVISLKSGLFQESETLVGVARDQGANSSRVVTLDLRKYQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCU2</accession>
    <name>A0A6A6PCU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCU2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="19247" checksum="311382CA3E7A867D" modified="2020-06-17" version="1">MCNGMSVGDARGVLLEVINNFHPCVKLKRDDCCREPPEQKTSRDRFANTVDYKTSGTLSGRTIGLKGEGLKPMSQAAHPRSDNRAGHFARLTRARACSDRCAADHLPRRRHTDRASRPSRQTRAFRDEFAIGRGSKANIIGMAHVITRGHDGAPTQDKSRGREDPAVEIDRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDG2</accession>
    <name>A0A6A6PDG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_86762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDG2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025529540" evidence="1">
        <location>
            <begin position="19"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="14053" checksum="D5567B4B1B658555" modified="2020-06-17" version="1">MPAPTIASFFCWLRRRRAVWICAQGSAMSPFPPMPPRLGLACFARAWLFSCASPLEPFRRPIPTVSRRWPTLPTDCSLTVRSGRRGKPACLLARAGFRASHRSQAQSHFLAHHAPAGGSACPRCRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDJ6</accession>
    <name>A0A6A6PDJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid/polyamine transporter I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_360595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDJ6"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF5">
        <property type="entry name" value="GABA TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="521" mass="56511" checksum="66AE607BAD26E95F" modified="2020-06-17" version="1">MEEDNKTFEMTVHGEDRSPASDAENGSMGPAGGAGALGDVRQRLDRFITLKPAVAFGLTVLSSWEGLALTFGAALLNGGPSTMVYGTIVATIGSLSLSCSLAEMASITPVVGAQYRWTSLYAPRVMSPEFWGLVQGWLTIFAWISLCAAVSFVAGTVVQGLIILNKEDYVPEAWHGTLLQWSYLLVPYLCNLFARKILPALEILGGIMHVVFFIAAVVTLTVLAPRSSAEFVFNSSLFGQSGWTNEGVQWCIGLLSITAVLTGFDGVLHLSDEIKNPPRKVPRSMILSVVINGVLALAFMITLLFCIGDVEAAVNTPTGYPIIQVYYSATKSKAGATILTIMLLIPMLISLFGVIASVSRLAWSFARDGGLPFHEFFGYTHPTLRIPLNALGLVVVVAGVLGLINLGSTEAFFAIVSLATLGLYVSYVLPILFMLMRKIKNQHPEYGPFQLGKWGIPVNIFALCYAIFIIIWLPFPATQPTTANSMNYAGPILIFVILMSLVDWFISGHKRFHVPTHYKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE14</accession>
    <name>A0A6A6PE14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_330223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE14"/>
    <dbReference type="OrthoDB" id="5327700at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="387" mass="41940" checksum="96CF81A4AF7BC917" modified="2020-06-17" version="1">MPSFDDRRERRSTLGYWMPLFLSVAVATAGAVAWVWSQREDESDSEDDNLSYGEHVRLQPGEETGFVARVQGAVRRTPSPQQFFDTASKRVASVVGGALSSITEGEEGDAHHNPWSEEAARRDITGAAEARSGPSQSRPAPNIKRRTVAVCITADASDSFREEDQAAHYNEHASLLSHIPHVNFATTNFFVLIYAPHLKSQSTSSSNRPASLGSSFSAISTPAQTPGDEKLSQLEPQHYTPGTTPALSATHPESPGALFAGLNGQAMQLVEKPTMVMPFTTPTSHVHMLRHLAPDMVYMAEAVAGERGENVEQVKDWVGQVIVVVGGDGVGLSGLVDTEDEGEGEGNNRPRERWWESAEMVGLGKGVDVVDAVRFGDDFDRRVCGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE81</accession>
    <name>A0A6A6PE81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_277970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE81"/>
    <dbReference type="OrthoDB" id="2687452at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="10785" checksum="CC74D4637E8FD514" modified="2020-06-17" version="1" fragment="single">CWYYMKYRGKNSFKRRDHRLQHLRNYHHMGEVDGRFKKSCFCVDCPAHRDGHNYTEFQCDQIGCERASTKGHFRKTDHRKRQRKVHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED6</accession>
    <name>A0A6A6PED6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="147" mass="16394" checksum="D34D25622B8939C7" modified="2020-06-17" version="1">MDELNADVYRLPWVHSRQIHPLHGRMSEPSAQQHASHPGHPIGQLQRWLPKRFGRDSQRQGRWGGRHSRWRPADAGWLVDLVHVGWVFNWTVPSWAAGFCGVADGPVPGETSPLPVRGIGAVLGTLGDLGRQNVLRPPRRSPLCIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PES6</accession>
    <name>A0A6A6PES6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH-ubiquinone oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_383265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the complex I NDUFA8 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PES6"/>
    <dbReference type="OrthoDB" id="276296at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016680">
        <property type="entry name" value="NDUFA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017016">
        <property type="entry name" value="NDUA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2462310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="17402" checksum="F6EAC696BA6C823E" modified="2020-06-17" version="1">MSARQPRFNQQVLIDTTPLPDDVPKVQEVGASSAPLMSASFFIGARCKPYNDDYMMCKTDANGRGELECMREGRKVTRCAISVLDDINKHCLDEFRAHWKCLENNNQQMWKCRLVEHPLNKCVFDKLKLEKTIPGTPEGQAPVHTKKRSIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF03</accession>
    <name>A0A6A6PF03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF03"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="9568" checksum="FBAB61E82CF28178" modified="2020-06-17" version="1">MRARGHFFLFFLALGPFGFWLWLWLLAFGLFTGHGRGRGAAWDPDMCVPLLVPCWPFLFVFVFWSWAFEACGRDFRKVMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF08</accession>
    <name>A0A6A6PF08_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_13190</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF08"/>
    <dbReference type="OrthoDB" id="15954at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000002">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000003">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="13">
        <location>
            <begin position="75"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Leucyl-tRNA synthetase editing" evidence="14">
        <location>
            <begin position="259"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="483"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="791"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2462380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1020" mass="114711" checksum="B7EE329B83A18BF8" modified="2020-06-17" version="1">MIAARLGAVRQWPRLQRPRPLSRQASSAPTRLDFQRIDAKWQKRWADADAASRAANPNPVEIDPTLPKRFILPMFPYPSGSLHLGHLRVYAIADVLARYARLQGYQVIHPMAWDAFGLPAENAAIEHGVDPAEWTRENIDKMRKQLKLMGGSWDWSREFMTCDSSFYRHTQNIFSALFRAGLAYQGTAVVNFDPVDNTVLANEQVDAEGRSWRSGAVVEKRRLKQWFLKITHDQESLLQGLGQLAKNGRWPERVTSMQRNWLGKSKGHEITFQIVSSIRHGHLQESRSTVQVFTTRLDTLFAAQFLALSLKHPLVQNLAKANVELRSFINDNSHSPPESTAGFCLPGVWAEAPLKDMDATKTDPSVRNAIPVYAAPYVLSDYAEGAVMGVPAHNSRDYAFWRRHMGEGAPVLNTIAPTLEAAASAPVYYRCDQTTPFLFKGYLTGAVPRRFRGLQSDKAAEEICHALSKSDYPAKPKDQFRLRDWLISRQRYWGTPIPIIHCNSCGPVLVPSDQLPVKLPELKPDQLREKKGNPLGEISDWVNVPCPQCHNPAKRETDTMDTFMCSSWYMFRFADPHNTLEPVSPDRADSTMPVDVYIGGVEHAILHLLYARFISRFMATSNIWPAGRDIKPVGEPFVKLISQGMVHGRTFSDPSTGRFFRPDEVDLTDPNNPRIKSTGETPNVSFEKMSKSKYNGVDPTKCIEKYGADATRAHILFQAPVTEILEWDEGRIVGMHRWFGKVWKIVDNARNSMWNDELEPAPEQVLDIEHSISKYEVDGFTDAEADLWLSAQSTIKAVTDALENTYSLNTLVSDLIKLTNAISAAKISSLSPGKTRDALGEKAVRTHIYFASTTILLRLMGPTVPALAEECWEYLFLPKPTGNPQQSQPVFSVSRTRNLDDPMPRTTGIFSLPTSRIKPSFPREDERVISKLSSRTHICAVQQNGKLRFVARIPFPPSHLNQNESTVDLIQWATQQIMETDEAKEYFGPKGLQKFGLVKKVVVAKGGKTVNFVTAKPTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF12</accession>
    <name>A0A6A6PF12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mso1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_368470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF12"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028095">
        <property type="entry name" value="Mso1_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14475">
        <property type="entry name" value="Mso1_Sec1_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mso1 N-terminal" evidence="2">
        <location>
            <begin position="23"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="350" mass="33405" checksum="7C8A6FADC947CD5F" modified="2020-06-17" version="1">MSSLFSNLLTTTTTRYTTLRSQLLSSAAGDADGDTADDTHVCRVLRAYYAEKGRPLPPWLPPDPNAPPAAAPAAMVSSGRGGYGGLGGAGGEAGAGRGRLAGGIGLWDDGGGAAAAAQQEDERISLRRRPGAGGGGPRAGLGRQQPPPPPPQPQQPQPQPASSRPLPSQRAGSYQAQAQTRRPGLPEPAPSGSSAASAASAASASSAQERLKARLWGSSSASAAAGGGGGAGGRSGSPVNSGSRAGDAGYAGVGAGASAGARPGMFDRGGSYGSARSEGGGGGGGTNPVMSANAPWVGSDDFGYAGYGSGGGYGGGGGGGGGGYGGYGGGSGGGRSGRGGMGLPSGPRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKS7</accession>
    <name>A0A6A6NKS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_176261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001718">
        <property type="protein sequence ID" value="KAF2452256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKS7"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="382" mass="43040" checksum="8E84208BEA0176C5" modified="2020-06-17" version="1">MSVDFFEEDWVGDNWEDDDLLADAGGEIADAAQQCISQPGRLHEAFRNTFNSIKLFGFSAFIKTASVEEQSGAMSEIKDVIAQTLGQQATTQSAAQNVTSFARQLTSDPGSLSNQAAIENVTEYLSLHDTSSDDVLQPSQDPQNRRSAKIFELEEYSEPLCLSEEYVCALRLCGYRHVPGNENHFFFDSVIARKDDGSHQWTPVQFQLPRKTREGDRVGLPADPADVKDQSSTQEVPFIALDDFCTILTWNIRCFRIYVTKSFETGGFCWSKEKSFSNVFPRQGAPMLLSTALKQDELSARHKILLAFTISKAFWQYYDSDWMSVEWSLETIQLLQTSSLDSEAPFLKIGSAGFEDSTYRKHGSERMSEEQRALHILLHGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLT0</accession>
    <name>A0A6A6NLT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_294398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLT0"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="79"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="18365" checksum="32A366430E8A6CD8" modified="2020-06-17" version="1">MSDAGSVQPAPEPTVVQGTLVPFANPLADEKEDKKIMKAVDKATKHAALKRGVKEVVKSLRKSPAASLASSGLSLANPAAVCILAADISPMDVISHLPVLCEDHNVPYVYVSSRARLGRASATKRPTSVVLVTKDKVRKRKEAEKEGDAEEWAEAYAQLVKVAKKAAKRVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLW2</accession>
    <name>A0A6A6NLW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF35</name>
        <name evidence="9" type="ORF">BDY21DRAFT_388431</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLW2"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000328">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="194"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="275" mass="30391" checksum="0249596D543E481D" modified="2020-06-17" version="1">MTDWTLDDDDDALALPQSQITKNKDGTETIVTYRMEDGKKVKTTRRIKKTVVKQVVNPRVAERKHWTKFGAEKGKPAGPQSDTTSVAENIVFRPMANWKASAEDKTETEKKKLAMKDAKIKCRICSGDHWTTKCPFKDTMAPEGEPGGAELDEAVDATGGLGPSGSSYVPPHLRKGGAATGDRMGGRYERDDLATLRVTNVSEFAEEQDLRDMFSRFGHVTRVFLAKDRETGRAKGFAFVSFADRAEAAKACEKMDGYGYGHLILKVEFAKKSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM49</accession>
    <name>A0A6A6NM49_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_151960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM49"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="177" mass="19910" checksum="D3ED9B9FEED2E8B6" modified="2020-06-17" version="1">MGKVRPWLSLSRHRASHVRGTIYTYSVPRRLLTFSFFWHLSHVRDAGPAPFCPRSARRESASFLLSHFLPLREEASRQRVRFRGRRSHTGPPARARARAGWAMLDSAAVAVCSARHSQINAYAPCHVCSKHVTVRARAEKRAVAVSSWLGTLIAPLGSRAFTRTLLERGPSRRCGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM57</accession>
    <name>A0A6A6NM57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_152147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM57"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="48"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="283"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="319" mass="35789" checksum="5E8C33ED139F99A0" modified="2020-06-17" version="1">MPPPYVPDEQSGSGSEGYAEDIPSKRGKAVKPEPAEDEGEEDDSEEEFVVEKILRHKWMDVSICAWSHSISAKAPHDALEQSLRLRRQCADAFTLKDLLYFQVKWLGYESASDRTWEPEENLATAPDVLREYFKKIGGRPERKTIKVEPPSTERKRKSGVSSVSGTPTANASGCGRGRKKARTASIENDGSDDDGPVGDYLEERIIVRKHADWVPPKGSWETYIQKIDTLEENENPVTGNVERVALVQWNDGRRSQHPVRVCNQKCPQKMLQFYEERVVFRTNPDNANNADNANNAGPAENGNGMIKKLESESPVFESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN42</accession>
    <name>A0A6A6NN42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase/reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_367439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN42"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF7">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE (AFU_ORTHOLOGUE AFUA_2G00830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="30659" checksum="D64BD236CA7461D1" modified="2020-06-17" version="1">MAAVLTKGTTAFITGAGSGIGLAVAKKCASVGMNVALADKNFEQVQKAKENLSGKGGTVDAFEMDVSNWSDWDSTRTKLLQQFGGVDFLMLNAGTSEQGTWGDAEYFRKIMETNLFGVINGLNALLPTMHESHKDISGKPAAIVITGSKQGITNPPGNAAYNASKSAVKTLAEHLSFDLRHTGIGVHLLVPGWTYTGLTGGPPGGHGEKPSGAWWPEQVADYMVQKMGDGKFYIICPDNDVSQELDKKRMLWTARDLVNGRPPLTRWREDWKNEAAKGVEEMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNA6</accession>
    <name>A0A6A6NNA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleoporin Nup186/Nup192/Nup205</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_142746</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2019644at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="602"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1690"/>
            <end position="1733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1718"/>
            <end position="1733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2006" mass="217163" checksum="29638E84DC777B88" modified="2020-06-17" version="1">MAEEDDGGLEWLHRDLLALSELRLPNVDRLWAQLEVRLDEFRRLLEKPGRNDTSRNALNTGRITIDDTEYQVNDDFKNDTAEIADALDLDELRAARLYLHAQQRSHEYDRRPLLAAILTFHKRREFLLECLRILVSLAVDTDTDDEKLPGEVREALRRSVRLVLNVQNGNVSNGSTFFRRCIADLTNMERWLQGLANRLQALSVIGQTMSAEGVEMINFQTASLTRQHESLASIATQLVRSGYTSLGDLRHSLDVVRNLDRYGVTLLHHIPILMALMAQFGSSDGNATLCDVRKLHEVVVSPGARDADAWSIRSFHAAVIVWWLGEYSGRYVDAAPGVQSPLDDVDLEAEAEQRSKRFMEALRDGALHFMLTCCEDVRRPRDWVDPVRSGIMSALLASQHYSYEAYSVGEDAPPAAEHFRTLFMEGMQGFVESFITNMPDTLRKLKLEEDEARRQLQSRFQRPPAASSRQANSSTTGERTGQPPVEYELHLERFLILIALAFQGSPSGAIDFWQDPEDNLFGFLQWAAKRQTTPRAAAFCEMLRALSEGEACAGMAHRFLLDDSPTASSSGKLRRSSTLSWNQIFAELRFYATALKERSSGSSLPPYLQHQQQNQQPHLSSSFANGTTQHQLHHASSATAAAAAAAQFVEPESIFMLECYLRLLAHLARESRVARAFILEHQSFSFREVLFALCADPAGSSGAAPLAAFIHTHHAQRDRLRAAALDALAALLTDKTGPLRDAVWASLDAWINTAGLPPAVAAAASQAFAHTTGPPGTPQPLPSSPWNEAAAFEPLAAGFEEPDAFVRFLLSLVTPGAADAEEVVLGIAAAAPQEDGGGQAVGLVEGGGTYLHDGLPFPEQLGANYRTQVGMEPYVDFAVGRVFGEKTTRESEMGSLKEGQLSILRLNCLNFIGACLDTWNDDLVLLANGQSAVPVEHLMLAGSLEIYCRLHPFGRVMEWMFNTKVIEALFATAHQDVSAINDAQSDSPLVLALLKAIQVIDRVLQLQATYFSILHPLLRKEAEKNSGVARSRSKPVVTSAISSFEDAILNHLNIVVDLGLYCGTGHQDLTVASLKLLQTLSSNRKLAASPTAGFGSRSKIIGVLEREGDAERIAHTLTDAMAMDDQELEAWPNSPGYDIKVHVLDFLNKCLETVPDRPSMAHLLLGFTCVGGTAVEIADDSLFAKGLSLFHAVLRIAVLLPDADVAPVGGPTGGAANNFVPWLCSLKARANAVLTKLWRSPLTAVYTLTELRANETLFLQACATRIVESGAALFSGMSPAQSVDFIIKNDAVAAYVGFLRSRAAFFEYAARELRATVTNGTPSLRARILASLLGTTQLPPGLVEGNQPVENPTIFDLFDFVELDVVSAARLLPARDPPFIGPIVDAIHAVCTVPASEGAGDGFKFDMHRVEMMLAFRLREIRVRVMEGAPGAPVGPTEEEQVFMEAGHTFQVLGAQNARREVEDSRRAALHSWAQLVTVVVGSCGEREFGGHEVAPEDTKKDGGTRDQVRGLATLREKLGSIGEKGKDDGSGACQGGAQRGVGHGLKAGFVLQAIQVILPKLEKAFATQDHFAAVELAGLASKMLQAVDFGVATGMRPKRGSSNDYNRGRNGASLFASSLALSTVAADANGTRTGTGGASRAADFANARLFQLFRVALSGIALTDSPPLLREMCYQIAFRYLRGLAGAVPTTSRDNDGSAGINGSINGASTRGPDVNGTRTPSSRALTRSTSGPLSQLNARYAQGGAPAGGSKSSPQIRHTIRAVKAAGARVVEVACDDAYGGEGTWRVSALIFLDGLVALCMREGDAFLLEALEKSNFVGVLVDAVKGVPEAVVAVGRGDMPLLLSYYDAALALLLRIAQTKVGAALVLNAGLFAAVRESMLFSVDPDIGLDTDTLIPLTSYYTLLLSVLSVINAAVLSRGPQHDATMAQAQRFLADHRHAVVGIFKRYAGIGRGGFGQRSGIGKEEMRVLNELVDGFTLLISATSFLEFEERTTFSKSPLQMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNQ1</accession>
    <name>A0A6A6NNQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_382209</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Chromosome</location>
            <location evidence="11">Centromere</location>
            <location evidence="11">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNQ1"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.30:FF:000001">
        <property type="entry name" value="Probable kinetochore protein ndc80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 11" id="KW-0137">Centromere</keyword>
    <keyword evidence="3 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="14">
        <location>
            <begin position="155"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="764"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="430"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="639"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2453318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="785" mass="87408" checksum="F6020A55C3CCAFA1" modified="2020-06-17" version="1">MAQESGAFSVRRPRETLGGLNHNASAIPMPTSAMKRSNSVSNLPQPGFTGGAAPHHGRSTSSSRMSLAPHGGGGAAARPQSTQPVFQRSSSGTNLADLGYNSVHRNSSTNMRKSFAAGAMAATPAHHPAGGAGMMGYATGGSAGVAPMSLDSTTQRRSSVYGSRPSYGTGAMGAHGMRQSFFSTAPPAAGIPQDPRRLKDSGVRAQMANELMDYLTQNGFELEMKHSLSAKSMTSPTQKDFNCMFQWLYKRIDPSYRFQKNIDAEVPPLLKQLRYPFEKSIMKSQIAAVGGNNWYTFLGLLHWMMQLARMMDMYAAGHYDDACADAGYDVSGDRIIFDFLSDAYRTWLSVDDEDDDGDCDKLIRPHIEQMAARFDAANAQHLEQVKMLEAEHKSLTSQIEELSKAGPRIAKLDEHIRILEEDKVKFEEYNARIDAKVDKLHAKIAQAEDELRQVEQELTEAEQEKQHLQEMVDAQGITIGDIDRMQTERERLRKNAETTATRLEESRRRVAEKEAEAGRKLDELERLIEKFNSLGYQIGLIPSTAPNAKGNEYELVLKVSTTNGTVNFTASQLGSSQQGQSLDSSDRLLAENGAGYQPHQLLNLDLRGAVKSNILSLRKDVGERRNAALEADMNNHDLLHKIKEAMDDKQAEVEALGHKVNAAEEEFEKTREITTAQKMASDTQIERMEKELAKMRAGLTESVQLMEQREMNTNIEYEQLTLRAASLREELHTEIERMLNDIIKFKVHIQKSLEDYESFVAEELERECEEQEMGEAEEQQESNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNQ9</accession>
    <name>A0A6A6NNQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_293162</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNQ9"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="100"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="339" mass="39501" checksum="355478777DAC470D" modified="2020-06-17" version="1">MTTEVSPTRLYLGNLPRTATKADVESHFQSHGTGKITEIKLMNGFGFIEYEDAMDARDVVPDGSDFMGERLVVQFARGSRRNPEFQPQERTAPRPRRTPFRMSITGLPTETSWQDLKDFARSNGLDVVYSEVSRERDGRGFVEYETQADLRKAVDSLDNHEFKGQAVHCVVDVSLPSSLSGYRRGCRGWKRDTQNQQTQEDRPRDRYRSRSPQPWRRYGPPPDDYYDRRGALPPPRGYTPQPRDDYRRRSPPRRDYYERDRYAARSPRRGPPVDDYPPPRARYPDDPYDARGPPPPRRGYDDPYINGHGRYDRPPSPRRGRTPPPRPGYEDGYRGRPYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNW2</accession>
    <name>A0A6A6NNW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Purine-cytosine permease FCY2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_293019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNW2"/>
    <dbReference type="OrthoDB" id="5428495at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="505" mass="54909" checksum="2FA6C724AFA5D746" modified="2020-06-17" version="1">MEVKQSFDTPTPTTPEPEVENGSVSGGLTSTSFWKTWARDLFLSVETTGIQRVTEEQRLQSPTKVWNACTFWMSANMAVATLNVGSIGGVMGLSFWDCFAIILVVNLLSCMIPAWTASFGLTGLRMTTFSRYSFGYWGNLLVVVFSMVATTGWNAINSISGASVLYALSDGKCPTWAGVIIICTTVWIICALGITWIHRFDAFLWIPPFIVWCVTAGTGASTFSGTAVESPKGPNGAASALSFIAVIFSFAVSWMNCASDYNVRMPVNTPRSRIFIATYIGIIVPTVLVQTLGAALYSGTQVNADWKAAFEAGGIGGPLREALAPAGGFGKFLMVFAALSAIPNNIPNNYSFAMHAQNFGPRAIRIPRLYLVTFGFVAAILVGCFASKYFENTLETFLSIIGYWTVIHLVVVAEEHLFFRACRWSRYDFDAWDKPALLPFGWAAIGAFAFGFLGAALGMKTGWYIGPVAELIGKQGANIGHEMTFGLSAISFPVFRWLEKKYTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPD0</accession>
    <name>A0A6A6NPD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_355400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPD0"/>
    <dbReference type="OrthoDB" id="19394at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="635"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="834"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="854" mass="94602" checksum="EA232E103154AE37" modified="2020-06-17" version="1">MTSAVNRPMDVKMKEKDINNKLQFFGIYSAFARGKVPSNKQIDVAMNSFLESKALASPSKKLSPEGQKLVGEVRDVVEQAKLLLLTKNEGNLLQDFIWQTQQLSGTAGEAQKPGAPVDKETAQQHGNEALEGLRTLGTLLITNGQFRKLLNDATIIMRDMIGDAATSTAKRAKPSEDQLNQLDQPAEDNTWHDVPDVKAMRENAKERYNQNKPFAKDSAKKATENASATANPEGNADPAATADAAANEQPVNANGGLKAGADTLKAQAAENTSDETKEKAKTWKTQSKEYFSGKMPQERREQTIWRLKKMVVEIQGHQDYLRAIETLLRLAETYGGHGRTVAKDSQGKVKGAHSDDSLQIAEADLKTLIERFANGTSLDDLFDSINAIYRDAEKDPELRQWFKDVDGYVRKCLKEQGFIMEDAAKDDWNGLYDRGRSLLRERYRTHTDRVVDEFKFIGKQFDEDPQNKAFSQSLQKLVMDLGNDENGKPVFKKHLVKDLTDVIIPAVFEHTRYVPVPRIEISDPMVDCVIENLVVESDNLAPNAVEFSSDNYWRWGRKKIANKNKNKVMLSSSGTQMDLKDVSYYVKKKQGFPSITDTGVMDVFMGGQGFSFKIEMENSDKKDKTHFFKVNKVDVDIKDFKIKVKQSKHKLLFSLFKPVAMKALKPAVQKALEKQIKDSAIKLDALLFSVHQEAEKAKEDAKRDPSVENVQNIYQRYLTAVKNQLAKGETKAQEATQDKKVNMAVTQHEAIFKDISLPGGVSSKATEFRDLAAKGDKWESPVFSIGSAKETQNLPKAPSVARKPHGSSSASGNALSPEPSSTKGFGNEVDKAFGTSNGTATATADNSGSANAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQC3</accession>
    <name>A0A6A6NQC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_387817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQC3"/>
    <dbReference type="OrthoDB" id="329563at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="634"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="668"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="702"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="804"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="868" mass="94600" checksum="CE26FDCBF23C862E" modified="2020-06-17" version="1">MPSLTTTATASSTASTNPSIASHLRHLVYYHLDNEAAHNAHFFATRLQALEPRSADAAHLVALCSLRLGHLRAAYDTAKDRIAVVVVGGSGIKGGGQQAQQQWHMGCAYVFAQACLALELFSEGITALERAARGGWVGQRSGFYKHSETTRRHLPDAPAVNCLLGKLWRAHGDVHKAVDYYVDALKENPFIWDAFQDLCDMGVDVRASNVFRMSPELAAAAGLTSRASSPTIGGAGGAQAPRQGHHGSIATPGNDPFSSTSRTGSDLGLNPGGSNLLSRLNETTTRYLDIETPSGNGIKPQQHDEDVLMGDAVPAVEGEPPTAPMRRPTRAVQAISSSDQTAVDAPRMRPITTRSRLKTGSETADAPEPNRTLPVPTHKRTISGHAPTHNSSTTGSASTTASTADASSSTAPQRRSARLFSQIRAPGSTKLATSGNSTRDIAAADSAKDKRELRKVRATGTKGSRSAASSTSTVGRVVSGNRKLHEPGDRDGKEAGSRPPSVASGATTQHQVMEPQPDPREREALAWLVELFSKLGAGYYHLSRHQSREALQAFSSITPPAQRDTAWVLAQMGRAYHDGFANVEAAECFARVRKIEPARLGDLEVYSTVLWMLKRDVELAFLAHELSDQDRLAPQTWIAVGNSFSLQREHAQAISCFRRATQLDGRFAYAFTLTGHEHFQNEEYERAMAAYRLAVAADARHYNGWYGLGRVFEKMGKLDAAEVHYNAAARLHPRHAVLALCVGDVLCKMGRPQSALTKYALACELDARNRFAHFKRARVLMTLRRGREALAELLVLKDQVPDEANVHFMLGRAYKMLKEPAVALRHYTIAMNLDPKRYGWLKASHYVKEAMENLNEEDDEDLYDDEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQE1</accession>
    <name>A0A6A6NQE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1264-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_355625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQE1"/>
    <dbReference type="OrthoDB" id="1901244at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="26128" checksum="95369FBD40B37D92" modified="2020-06-17" version="1">MESRPVTSGAAGGPLSTKSRILEAGANMVQDFRPVNQICAHLNAYHAYADEPGRCVEANHYCSHLNEDIRQCILYDSPEKGARLIGVEYMITHRLFETLPEEERHLWHSHVFEVKSGMLIMPRPSTVPDAVWETAETKEMEDVVVLYGKAYHLWQVDRGDKIPLGEPKLVTSFTQSRQMEPCGGFEKLVGERDSRFGESWKRKQEIRSGIKEPEISTSVDRAWDQVRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQN5</accession>
    <name>A0A6A6NQN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA-capping enzyme subunit beta</fullName>
            <ecNumber evidence="8">3.6.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-triphosphate monophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_114288</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67004"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
            <dbReference type="EC" id="3.6.1.74"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:67005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the fungal TPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.74" evidence="8"/>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQN5"/>
    <dbReference type="OrthoDB" id="272147at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031533">
        <property type="term" value="C:mRNA capping enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140818">
        <property type="term" value="F:mRNA 5'-triphosphate monophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004651">
        <property type="term" value="F:polynucleotide 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.10">
        <property type="entry name" value="mRNA triphosphatase Cet1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040343">
        <property type="entry name" value="Cet1/Ctl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004206">
        <property type="entry name" value="mRNA_triPase_Cet1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037009">
        <property type="entry name" value="mRNA_triPase_Cet1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE CTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02940">
        <property type="entry name" value="mRNA_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="4 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="10">
        <location>
            <begin position="430"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="191"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="191"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="524" mass="55560" checksum="B03A4D05B535935A" modified="2020-06-17" version="1">MDLRSLMNPSADSNGLSQQRHPHPQPQPHPYHPHSASPSAVASPGGPPPISTPTSATAVLQTPLGNQQQHFFPPPNPSHPQLLHSPLQTQHSPPIPQLRRQRTSVSLSSSPLASRGSPEAVVHQHPGIGSERTGGVPGSHRSSIHSLTINNKEAPPPPGPQQGTTPVTPAAAAGGSPVLAGYQAQYQMLLQQQQQQQPGQQAFGLQAQQFQQQQQTQAPQSQFSSPRSSSHNSLPPQTPQQPPPSHYQQSQPQPPTPTQHPNQQHSQYYQQQPPTPHPPPSRSHSIATPSPVTAPNMPAAAATTTVTATASVAPPRSRTTSTAAPSPRVPPKLLSKRYRPVPIWAQKDEEDEEGFKPKGMRGGEHQPGTAAARPADDAGGPPPQEQYPDGAGPPPPVPPHPPEEAETYLLGDGATPSHWEPTLTNNVPYDEVTRAVADFVFNAAVLSELPPGFVEIEGKLGMLVERDAPKAVGGQGLEGWRLQLPVGTETVLRDMGGGVGGGFRSSMTTVRSRPLPLLACTVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQU3</accession>
    <name>A0A6A6NQU3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 18">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 18">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDY21DRAFT_354099</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 21">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 18"/>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQU3"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 18" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="23">
        <location>
            <begin position="169"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="26"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="527"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="19">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="19">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF2454101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="611" mass="69110" checksum="1FA2B52339FB9DDA" modified="2020-06-17" version="1">MPQVTNGGPNVADGLAPGYIYVPNSGYQALEEGDPRQVRDREVDNATEPDGDEPDGYDDDDFAASSDFDSDSYEASSLAISNPSDYTKIYNRDRRQHDPNIPASELRGTNPQHVSRRPKPSANAAAAVDDQIAAMSRHAAKIKLDERWGWGTTVGGGGKGLEDKIREKDKADRATVEKVLDPATRLIMLNLINNEILSEIHGVISTGKEANVYHALSGPRMDEQRRTLALESGGAVQPVCGEQQQPVHLAVKVYKTAILAFKDRTPYASEDFRLRAAYKKSSHRQMVKMWADKEMHNLKRIRAAGIPCPEPFHLRLHVLVMGLIGDSHGWPAPRLHNIKFEDTTLDEALATWTDMYRQVLGYMRIMYQRCKLVHADLSEYNLLYHEGKPYVIDVSQAVGHEHPRALDFLRLDIKNMSNFFERKGVDCLPERAVFNFIVLMEDGSQDTENIPAMLDELYENHKKELEKEYESGVAVEDLEAKKEVDTEVFRQQYIPRTLEQVYDIESELEKGEGDELVYKALLSQKVANGDRPSDASESGAEDNDTDSESGSQLSQHGKDDPRRRPRGRKFEDKDVKRQHKAAVKEEKREKRKNKMAKAQKKKLVKNSTRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR50</accession>
    <name>A0A6A6NR50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_387627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR50"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="124"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="449" mass="50650" checksum="998FD0843B0C4584" modified="2020-06-17" version="1">MPMWLCDFEGCRRPAVRTFGDCILCNRHLCSDHLQHAFHGCPKWEDADIYDPAARAAEARELTELIEKINIPALVARASLLRQGIPCSIPLLQYDRSTRSSVMGGMNYYVELSFDDGIKWIACIRSEVATLEFLELIDVPSPRVFDFALENANNSVGVGYILMEKLPGKSLRWALATQKQKKNIMNQLADIFVELHKYPFDLLGSLDHPGDTHIGAFAQESLTDFAQSEMRTIGPFSSPEQYHDSSLRLILDLILRGEMYSQQAVDAYLIHRFLVDLIPLVSPSPSSSSMQNDQNYYLKHADDKGDHILADEDFNITGIIDWEWAYTAPPAHAFNSPIGLLPVGNFYDGVNDLGDDEIVFARLFEEKGRQDLAGFVWNGRVQHRFAFCCGYDLADWSGFLGLFRGLRDAVKVDEGLDWNEWKAAALHRYKEDVGLQLLLSRHEVTAAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR56</accession>
    <name>A0A6A6NR56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_291717</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR56"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01448">
        <property type="entry name" value="TST_Repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01449">
        <property type="entry name" value="TST_Repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000001">
        <property type="entry name" value="Sulfurtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000033">
        <property type="entry name" value="Thiosulfate sulfurtransferase TUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="56"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="188"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="312" mass="34530" checksum="7FF20475AE2BA562" modified="2020-06-17" version="1">MTSYSLDSYIVTPAELNSALRKNVHSKLSTAPRIVPLCASWFLPNDPAERTGESTFLAARIPRARFFDLDAVKDPTSPYPHMLPSPKDFAASLGRLGIRKDDAVVVYDTSELGIFSAPRVGWTLKVFGHPDVHLLNNFRLWVEQGYPVESDEPQPVDPVQYPIPELDVSKVASFEEVKSIVKEQGKEGAEEVQILDARSPKRWEGRDPEPREGLSSGHIPHSRNIPVSDLLDPVTKALLPAEQLKAYFEGKGVDVSKPIISSCGTGVTAAVIDAALTEAGYPELSRRLYDGSWTEWAQRVRPEENLIVKFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR64</accession>
    <name>A0A6A6NR64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-hydroxyisobutyrate dehydrogenase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_387942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR64"/>
    <dbReference type="OrthoDB" id="2624308at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="785" mass="89188" checksum="0D6C425A33906621" modified="2020-06-17" version="1">MASSNDVDEYNDGPINRSVTRQRGYFHIFDLHTSFRLFREPHFYRKNALVYDRSSEKLLHRDVMFRLTEHAESDDRYISPFDGRIKRVVVQCVDDIYDNNNNHVTWRRTFIRNVSPFYMRLANWPTDHVDMTRFQPTGDEWVWIIVKWIPACAGLFCVLTFAQSAQGQERNGGKFDSFPYRFFGYPKVARNALEDATSKRTHREISDALNPIAKRLLRPRHLCFLRNPEVKHLQGMVPMDVEEWITQYRSERNLDYIFVAYTTEQFSHTSAEDMNALHQIAETAARAAGVAAYWIGCTCMPEAAKVHEDVYRISDVIRGAESLVIAVKRPTRDTGAIVTTHEMLEQWGSRIWTFPEVLLSPSGQTIKVYTWGGDLSQPMRLAKKQFAAKVWKRDSAVSRQLIDHFEGNCVLSHLELTTIALQCLYNRNTTQYLPGDHSYALMGLLRLRPTVDDTDSGFQAFARLSLANDSQKLMERLVGVMAKNPDQDWHCMDDAYGANLWDIEPSIQIAGIGDDDTVIVDGVRAANVRWKSFAIVRNLRRDSWKRIFARLAIRWAPLALFVGAWIVSFTSPPPSATASSSSTAGETGGILLAIGAILLVAGLILVLGAPKLLRVIYSGKFWLTQPWFFGFEGHMDIEGIERQIWGGRLQRLRWAPFGSPLSRHYRNELGECVGVDPCSDPNVRAKVERARHARCGEQRIFTLVDTNTMTVTLFESARPPIAVLLVGSEGGMQRAVGCSYDWTSGTLYKETVLRLETPCVDKMDLVSRIRLGLKRPFASTRGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR85</accession>
    <name>A0A6A6NR85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-induced protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR85"/>
    <dbReference type="OrthoDB" id="498286at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF2">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="25412" checksum="04AF2694DCAE518F" modified="2020-06-17" version="1">MSDAASPIATEVIAARIDASMLAMKDEEFEPHTWEELRKTIATNHIEVLRRRPSDTRRYVAWIEHIKAVYGDVRKYLLQERLRWTPLPVANTDANGDATPAAPPALTFACANAEPFADPADYLILRNDWPYGLEPGIAHVVVWLKTPLEADMARDGDLTDDARTQVEAFVTRTFRTAVGEDPKKKGSKVLWFKNWVKLQSVRGVDHVHVLLRDAPDDKLEAWMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRC0</accession>
    <name>A0A6A6NRC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_400558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRC0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="342" mass="35382" checksum="474EDA824D608331" modified="2020-06-17" version="1">MLAPAGKIHLKQSCVDNIASNDHTTSSTLLEVPQTPVSSAVVESRSHLSTATISASQRMSAKLTAMTTFRTSRSPGTLLIDTATPPPPAHPSAASSPSSSPISSTTTTATPPSSPTTTAATSDPLDLRSPAALLSSVRLNLGLGLAVGILALAAGVALGVYAARHFRQRLRRREQRQCSPDADAAALEAGGGRAPETTPAPAPQLARQQGRWHRARARRQSGHGRGGAYEVGGGEEVPVCELAAVPRVVELGGRRWSERRSGGRGGLAEKVGGAEEPGRKGSAWTGRVRSGAALRQDGGERGSAGGQGVGSPRRNTQRGTVRWLDPVAVAEPEPAVLKEVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRG5</accession>
    <name>A0A6A6NRG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_291936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5418235at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF2">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1328"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1344"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1385"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1454" mass="159976" checksum="E06D40775522735C" modified="2020-06-17" version="1">METAAFGQLPRRLTKLYSDTKQSCDSVTEQQDKFDNAPELTALHRKFRIQKDRLIAWGVEWSDETAAATPQEGSIDESVARAGLTETVTSVLSTIKDVLNEAEQMRSSSDGKTAPVTSERQSEKSWGRPSRSWSASDRAKYEELAKDLTSGIDILYDLSRSRRAFMQGTYPTDEKSTTPAGSATSKAAQQHVFQKDDYIHSDITLINPSTGLSTNTQVGSDIPLALDPSKLILPEEEPPPYESVNAPSTARVIGQLCRQHTSTNPWKSDGGKSIKTPVLVEYAMFDSVYRDTGVSPPLNRLEDLMKFLNRPRAPSDSEFGTLRCIGFFEDPKRPRYGVVYDLPRDILDGPWKEHREQPELLRPVTFQHLLQTASNLKLAPSPTPSAPPLEDRFRLALNLAITFNQIHSAGLKHKDVNSSNVLFFRKRHAHSSSSRRATHYNIRAPYVCAFDIFSEYNVEAVADGSPQKIYRHPADPKANQLSGATYGAQFDLHGLGLLLLEVGLWSPIADVFKPKYTLSVFKERIDQIYVKKLAGKCGTVYMNAVQECLAADSSNASSKLEAFVPTYRKVLSKLRRCCLLDESEPFDESASPLERTQSLPEQVRQGGVSAPTNLPTASQKAGSQMPAQTVPKDQGGGSPDSLRSLSKLHRSPVAKKILHPSHSFSRSPTETSIPEETRRRGIRQSFSNVTDTARDELHDISSLYKEQVTSAASVIQRAWRCHKDKITFKEYRYKVTLVQKQWRRRQSMRSSLATTSPTLTDNPHSQDPSIYSQIIDSQQRFQVVTEIPPPTVPKPKLRLHPVKCVPEILDQWHDRLLPRLERIVSRALKDSPESVSMDLVSVGETASTARPCIFITCSSTSRVKAALARRFSYDKATFELKVRCGKIRRSKVTRRPPPTPSNKQRVPPPHRSMANNAPFDGEMPALNPFYQQRPLCGASIGAYRDEHLPPVTYGGVVLVDGEPFGMSVHHLLDAPSDDEPDEEEAPRSSARSAGGNPWLMGMGDQPGLHLDDSFANGGALEISDDEASDDESLWEGSDDDDDGYSGDGVHALTSPLSSSSHSTIGDIPGIAPGKGEDIIITQPAIDDVDEDFFPEPEDRAEDHLASHTLGHVYASSGIRRWRLGNTVHEIDWALLKLRPDRIQPWNLVQGGKNENRKHKEGAESDAANDWYPKLLEPVCRRHFDAADDEYPSKVAAANELGGLAVHCFGRTSGLKGGVVGQAMSSVRVYRRRSFSRSWHVVGDFGVGGDSGAWVIDNTGARVCGHVLAWCARNAIAYICPMEVLLRDIQRSLGARAVALPGADMLRPDEVDAYARRIAGLTLEDATAAAADATRSHHRQRQWSSDEEDGDDEEEDSTDEAGVGEDSDVEPERSDSDAENARQGSAAAAAAAAAALRPAPRPQVRNRKRPARASGGVLLNMAQVPGIAGAEAAAASPQASPQKGKRGLTRLRQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRM3</accession>
    <name>A0A6A6NRM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_399593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRM3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="43373" checksum="5B5F0EC7D3EB0926" modified="2020-06-17" version="1">MEMSNPIAPTFAEAIREDLLAMLEFMDLRPPYSPEIEQFLRDVDLSQLITQERQSPASSSEIEQPLGDIDATSNLTLDSLEIEELLEGPDISERTTQELQDTASIPPENEQSLEEGGFMSEVARKECQSQTPLQRALCSPETGRSNSIDDAADSVEDASKSAEGRSISIDDIMAAAIREYENQRAREAKDHFLQTYSIRINAMKAGEDVAFLMYFLTHFAGRSYPPIRVKNLSVYLGATDLAWNRVQGRLEDVHWTSPECMLRVDVTMHELSKACRYHGLEIVNLELQFSNLHCFAFPCPTECWEANREAVRRFRRHLRGMVVKERCSVISYARKSHEESKRDVESFELCALAPPGKKVTPEMVPFIPEFVPRMATHECLCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS08</accession>
    <name>A0A6A6NS08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_353710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS08"/>
    <dbReference type="OrthoDB" id="5592879at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="11879" checksum="414CB933FE2D7286" modified="2020-06-17" version="1">MRARAVVLLAGLRTKVRVGFEVEAEAGLDVRGEETGCPRATPTLNVRVGTTAEVVYGERYKEDKMAEFLSSYVGEKVRNPAEMGVWADAVRELRDRLVARGKKGAVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS44</accession>
    <name>A0A6A6NS44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isoleucine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_353653</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS44"/>
    <dbReference type="OrthoDB" id="10264412at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000111">
        <property type="entry name" value="Mitochondrial isoleucyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.830">
        <property type="entry name" value="Ile-tRNA synthetase CP2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="13">
        <location>
            <begin position="67"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="15">
        <location>
            <begin position="780"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger FPG/IleRS-type" evidence="14">
        <location>
            <begin position="1011"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2454327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1041" mass="116660" checksum="490032DB5C3A307C" modified="2020-06-17" version="1">MVRPTRALFASYASTLRLPKSSFPARPSNADKYVKRCTDELYQWQRAHRPAPELLSTQSGKDGRNVDGDFVLHDGPPYANGSLHVGHALNKILKDIVCRFQLSRGKRVHYVPGWDCHGLPIELKALQENSTETGSNIGQNGPTSNETTEAAVVVRNKARKLAMRAIKEQMKGFREWAVMGDWNNAYKTLDKDFEMRQLAIFKEMVERGLIYRQNKPVYWSPSSGTALAEAELEYDENHISPAVFIKFPLLEYSEALKRTFDISDHKVSLLIWTTTPWTLPANQAIAVNRALKYAVIKDPQSPSNGRLIVAESRLEHLQSFFPSNPLEVVGETLCGSDLTNGLSYLNPLRQLSGMPILHADFVSESSGTGLVHLAPGHGMDDYNVCKDLGIAAIAPVDDHGRFTSQGLPSKLSKRIEGFPVQGEGTKAILDFLENSAKFDDADTSLVLASHQFKHKYPIDWRTKKPVIIRATEQWFADVGSIQNMSLEALQSVQFVPDSGKTRLENFVLGRSQWCVSRQRAWGVPIPALYRVDDSGKVVEAIMTGETIDHIIKVFQERGIDAWWTNPKNDPAWIPPNLSGNFIRGRDTMDVWFDSGTSWTLLPKRSADQPLADVYLEGTDQHRGWFQSSLLTHIAHQSIKKGNSVPPMAPFRTLITHGFTLDQDGRKMSKSLGNVISPEQITSGSLLPPLKRKKLKCKAQNVDEKPTYDSMGSDALRLWVANSDYTKDVVIGQPILQSINSSLQKYRVTFKWLLGVLSDFKFTSSDQRPYISREHALTLADRIALHQLAQTSTAVHTAYCAHETFKAVAHLNKFISHSLSAVYFETLKDRLYAGAAADRRSAQVVLYHVLSELLSMLAPVTPLLVEEVWDFMPTQVKEAMEHPARRVWSPFKTGADERERKEMDCKIDTLLALHSEVKGLQEKARAEGSMGSSLESELWLFVPQNLVRNDGFSRHIFGKDVQSELMGLLVVSNVEILGERDSTLGDVTVWAEKTISLLGNGVRLLLGPPKNEKCPRCWRYMAAQKEELCGRCYDVVHEINGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS95</accession>
    <name>A0A6A6NS95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS95"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="12359" checksum="AB2AF5C0B4F96077" modified="2020-06-17" version="1">MRAHAHAHQSRKFRPSPARRRLMPSIPLVEGCRADDASPRASPYESQPRYAPAGATRPGLQAPRPFSARRRGLVFGRLLARKRAWRTSPCPSCWELGSCNGCPAPAASLDPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSV4</accession>
    <name>A0A6A6NSV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase/lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_325369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSV4"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF105">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G08790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="280" mass="30335" checksum="F13A193697F5D656" modified="2020-06-17" version="1">MSTGVGMSSCCLSGKVKEGKPKGHVSQIGGLEAYISEPETGSTEKTVIFLTDIFGYEFPNVRLLADNYAKAGFCCYVPDLHQGDSLPISFLDDVEPSLREREQLSLTASAAKTAKVGATLGPWLIRHREAVTKPLMEQFIRAVRLIPGTDKVGVIGFCWGGRYAILATHRGAEPGLAVDAAVACHPSLLARPTDLEPVAKPLSLALGEKDSLVGEAEQKQLVGLMEMKQGQGQGVPTEVKIYEDQVHGFALRGDWSSDKDRQAMDDAEQQGIQWFKKYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT44</accession>
    <name>A0A6A6NT44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_97922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT44"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025677725" evidence="2">
        <location>
            <begin position="17"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="199" mass="19442" checksum="8F775A8F9158D2F5" modified="2020-06-17" version="1">MKYFAGAFCLAGLVSAAPVAQVMPSGEPSMPGGFPMPSMPSGFSMPTGGFPMPTGEFSMPTGGFPIPTGMPSIPGGFSMPTGGFPIPTGGFSMPSGFSMPSGFSMPTEFPSIPGGFSMPTGMPPMPSMPGGMSMPSMPGGMPSMPGSMPVPTDSVPTGGMFPGQPGAPVPGAPAPSGEGAPAIPAVPESPSIPSAPPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT45</accession>
    <name>A0A6A6NT45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_308309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT45"/>
    <dbReference type="OrthoDB" id="361494at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000109">
        <property type="term" value="C:nucleotide-excision repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042238">
        <property type="entry name" value="Rad28/ERCC8/Ckn1/ATCSA-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202:SF1">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="68"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="297"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="458"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="461"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="501" mass="53411" checksum="38BBBB11815F290D" modified="2020-06-17" version="1">MNAFLLNRALGTVAPQALERAYTHSLVRDIQPADVRLYGSRRGLDAALRGQRDDEAVAGEEEARRADAVAHLAGVNAIDMDRFEGRYMLSGGADGTISVWDFDQEERLVPRGSALAPVGQIPKSSQSHKFGITAVSFFPTDPYALISTSFDHTLKLFSTTSFLSSPPSSIPPEPAASYDLESIPYTHAPSPHPSSHLLIAVGLQHPAIRLLDIRTGSAAHSLPGHAAAVLALSWCPLPSRPHLLASGSADGALRLWDVRRSVPALAALDAEDSVGVLGYDGLGTGARHRSRGRAHGGSGGGAAVNALCWAPDGRHLVSAGLDEKVRVWDADRGANTLAAFGPLVRNSRLAGLRLECAPRGATLPRADVLAFPSDAEVLLFELWDGRLVRRLRTPDMVRAARAVPPPPMAPTSATGASATATATRVARARATAVAWRRGGGAPELVSGHGDGKVRVWRPWTGEDEEVEREDEEERREAEAGRKRKAEALEGVRRDVLRGVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTH2</accession>
    <name>A0A6A6NTH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTH2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="66" mass="7081" checksum="F311EC0D8A955538" modified="2020-06-17" version="1">MRVMQLQHRRASPAAAIKQGREGRRSLAPGESTGPAATAHPWLGPPAQPLNQAAFGLADLRARAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTQ5</accession>
    <name>A0A6A6NTQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTQ5"/>
    <dbReference type="OrthoDB" id="5317787at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="466" mass="53111" checksum="3A2533F85C2D4040" modified="2020-06-17" version="1">MPSSVSNDTSGSSNLSSRRGDAYSYSGSTAPTEYSSEVHYLTKTVEPPAYLCRQDPYAYERYPRYEDRAPPSRHQPDASADTYESTVPSDDEELDDGYPDYGLPDDMSNLRLAPQAEAATPKAFGELFPSSRPISIRHDDTTMDGNMNLRLDTEVISPRGDSNWVTLFHLRMHDLKDRDFSFRRYCRDSGREVCNSRRKYKNEQKHTQTEPSADFDSEEESLTTAFASLRRNNTDPLDGSQLNRQDSGYGSVRGSSDEQQRPRTATRTYTDLPPAREPTNTIKLEFSNYAHVNVKRHGKANHKHYDFEYWGIHYSWRRILPKDSHVQHPSWSLTRVNSDRPLAHIVPASLTPSETAEETCKGGWVPPSTFWISDPAVINNGMKDLSDVLLAAGLIAMVDDTIKTRFHSKWHTQLVLPLSRNSSFKIPVDNMTPKRLIDEVFHRGHRSELHIPLERPAHSRRGSHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY5</accession>
    <name>A0A6A6NTY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_416240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY5"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="29145" checksum="A4B816E0D1474608" modified="2020-06-17" version="1">MTSKAAVSLTCDHTSPDGPDSEAVPRGGVTGLVERLKSGDVIKSPWTGRPTASDCRQEMAIEAQIYERLGAHPRLVQLKYWDPVDYTLTLEYMPHGNLMEYVKKYGQKISPAQKQQCVMKASEGIEHLHSHGVIQGDIGPHNFLLDIDLSLKICDFGGSSLDGSRATVVPGVRYRLPSVAERHIQSATIKEDLFALGSTIYFIATGHEPYNELTDEDQVEKLYKDRVFPELSGVPFAEVIALCWRQEAESAKMIIELVKRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU21</accession>
    <name>A0A6A6NU21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_77927</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU21"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2455058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="470" mass="52339" checksum="3AC533E325AEF5FC" modified="2020-06-17" version="1">MTVATTSLTRTERLSLFSLTAACIGVLANTFQGDGEPLIASLALSGVAFSSSYALIRWLGDTFMRAGFKGRDMSKLRHTEIPETMGAVCAVVYLLMLIIFIPFPFYKDIVAATSGGGNRDIVLEVQHVEHGRFLHRFPHNKLASFLSALLSLHSVVILGVGDDLFDIRWRHKILIPAFAAIPMLIVYFVDFGVTHVVVPTPLRPYLNGAILVDLGWLYYAYMAAIAIFCPNSINILAGINGLEVGQSLVIALLLVLNDSFYLLLPSTPYPHPATDSHLFSTFLLLPFIGVSFALLAHNWFPARVFVGDTYCYFAGMVFAVVGILGHFSKTLLLLLIPQIFNFIYSAPQLFHLVPCPRHRLPKFNPRTSLLENSTATFVKPLPRPVAEAMKLMHRMKLLRIKTDESGEVVESTNFTIINLWLVWFGPMREDRLAMGLLGLQTACGLLGLFVRHRLALWVFTADNLSRQWIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU34</accession>
    <name>A0A6A6NU34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_72257</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU34"/>
    <dbReference type="OrthoDB" id="5244761at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="488"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="707"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1155" mass="127339" checksum="00059B77A2889E23" modified="2020-06-17" version="1">MDNGDPDVKSKRLRLDPQNSGLPPPVSQAPPPLHHTHPPPPPPPPPPPPPPPPQAPLPPPHAPQPSSSARPAPYSEPHPSHHPHGLPLPHQHPGPGPHPPQPPPPPPPHQPGSQHPPPPHYPRESTGTPLDSRPSVPNHRDLPHPQQHPPPSTLEHPYASRPAYVPPVNPPQAQQRSYSLDSPYTRPAGTPSQLAPAEPQRRSVVEGSPPSMDHGPQTQMYHPGYPDPHAAAPAHNGYPPMPKQEAPQQYAGAAMHPSQSYPPTPVTGYQTQYGAQTPFGSGGPAARRKQIRATMACNTCRQRKQKCSEERPCSFCRDNNHECEYKDVPPPKSERTVNELTLRISRLEEGMEKIYGFLVKTFAPGMPPMDVSPNVESRSASIRSIAPGPEADRPPPLVHPPVQDTPPLAFVPPAPEQNEADTVHETVNLPADEQVLPGDDVFSNEHTSPAHKLLEWPSIASFFTRDSPAHTNYVVEAEANRGLLRVWGRGEGEDNNDGSRGIRDQGSPANSSGSDDYPTPPSTDGLWGNGFEMGQSQFQHPHHLQPEGFRREHPGGLNPDGSLKFDEATVKRLMHSYLRHIHILHPFLDKRRLSNMVETFIRHYGVPSWPSFVPQSSMTGPLPTGMLNSESGVRMKRKRSEGPTSGPSPVMAERHSPMQTRRMPERTVGNAIVLLVLALGKICEHRDPLPALPGTVEYVAEHASQMWNSTDSPPSTIKPSPISSHSTHPSPSPTNNGYGFPRKLSAENIPISDRRDGNLRNIDVVPGLAYYAFACDILANIIAGNELAHAQAFLLAGLYMGQLTRVMESWTWINLASRASRLLVDKEREALKPPEPERVEMGQVFKSNSPRRTLIKFAYWTSLQLESDILAEMETLKPSGLSSYEERIGYPDNVCLEMPVDAPEDTENEISVMIFYSAQVQLRKILNRVHKALYSARQMGPPRGWASAGATLLEQQFEDWRNCLPPTFRWEDSDPPSPDINTARMRAKYYGGKYIVTRPVIDRALHQRKPIPIPPELVEDPSQIHASNLMARSMPPNGHRQINLKELRSCKTCIDAAIQSTIAFDGLRGRPIVTNMFGTAQAQFGNVLVLAAVHNSWLRPLIPPGKTNQLLDRTIKFLRQLSPISPTMKINVSILESVSKCINGEQEGSFGAPYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU85</accession>
    <name>A0A6A6NU85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_365519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU85"/>
    <dbReference type="OrthoDB" id="3782109at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="102" mass="11463" checksum="18EAAEACBF5F3B61" modified="2020-06-17" version="1">MDSLKFQVGTMKFLGMERQFSIANQEKAITHTFEYKDQLVSLVLDVHFFGLTTIASPTSKQDVLLDIVAVTGLAGHALGSWKERGGDFYEQLEKIRWNPSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUA6</accession>
    <name>A0A6A6NUA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_74554</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001638">
        <property type="entry name" value="NACHT and WD40 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053299">
        <property type="entry name" value="ASTRA_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44156">
        <property type="entry name" value="SUPERNUMERARY LIMBS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="393"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="927"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="969"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1011"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1053"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1095"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1137"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1179"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1222"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1263"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1306"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1347"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1390"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1433"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1579" mass="177811" checksum="E9630C03970A57B7" modified="2020-06-17" version="1">MFLTPRRQCTWCRRQIRHTAWYLSSDNFGNTQPPNPARPSEAHRNRPALSLPRFSDLIFRCWPAHQLRPRLTCRLELGQRNFYRLLSREAPQERMRLLQRSDAGEFEFAENLTSDDTIPPYAILSHTWKRDTEVIFEDMKNHTGKNKPGYEKIRFCGEQARRDGLEYFWIDTCCINKESYAELSQAINSMFRWYRNATRCYVYLSDVSSPLSDTNDEFNPRPWEADFWKSKWFTRGWTLQELLAPRSVEFFSREHKRLGDKSSLEQQIHEITGVPKSALQGAPLSQFSVNERLSWIERRQTTVEEDKAYSLLGIFDVYMPLIYREGTASAFKRLREEIEKLEKCLQDLRLTDPRDDKKRIEDTKGGLLEDSYRWVLENSDFQRWSSAQQSQSQLLWIKGDPGKGKTMLLCGIINELNKSMAKTALLSYFFCQAADSRINNAIAVLRGLIYLLVDQQPSLISHIRKKYDRAGKALFEDTNTWVVLCEIFTNILHDPSLSNTYLIIDALDECVADLPNLLDFIGQKSSVSSHVKWIVSSRNDFNIEWRLRLDGSGTRLSLELEENAKQVACAVNTYINHCLSELSEIQHNTELRDLVREKMLSKANGTFLWVSLVIKELKEVMSWDVLQVLEEVPTELKGMYHRMMKQIKLLRRNYPELCRQVLSTVIVAYRPLHLQELRVLSGLPTQVQNANQSIAAIVKMCGSFLTVQDDNVYIIHQSAKDYLSEEASHDIFPCGVGEAHHSIFSRSLQVMSRTLRRDIYGLHALGYPIERVEHPEPDPLAASRYSCLSWVDHLCNWNSNCCAKHGVDLQDGGAVEDFMRRKYLYWLEALSLCGSTSDGVGSMAKLETLLQGRTDASALFGLVRDAYRFIMYHKQAVENCPLQAYASALIFSPAHSLIRGLFKNEELKTIAIQPPIGDEWSACLQTLEGHYGSVRSIAFSHDSTQLASASDDKTVKIWDTRTGTYLQTLKGHSNWVTSVAFSPDSTQLASASDDKTIKIWDTRSGACLQTLEGHRDWVKSIAYSHDSTRLASASTDRTVKIWDTRSSTCLQTLEGYSGFVWSVAFSGDSTRLASALANTMVKIWDTRSGTCLQTLEGHSSWVISVAYSHDSTRLASASGDRTIKIWDTKSGACLQTLEGHRDLVKSVAFSHNSTRLASASEDTTAKIWDTRSGACLQTLEGHRNWVWSVAFSHDSTRLASASEDKTVKIWDITGDGACLQTPEGHYDSVRSVAFSYDSTRLASASADRTIKIWDTGGTCLQTLEGHRDWVKSIAFSYDSTQLASASDDKTVKIWDITGDGTCLQTLKGHRRSIRSIAFSGNSTQLASASDKTVRIWHTRGGICLQTLEGHRDLVSSVAFSHNSTRLASASEDKTVKIWDITGDGACLQTLEGHSRRVISVAFSGDSTWLASASGDRTVKIWDVTSDGACLQTLEGHRDLVKSVAFSHDSARLASASDDKTVKIWDTRSGACLQTLDIGKRLSEISFDATGSCLHTEIGTIAINASSASYTTPNVTKPQDLRFQGAGVSSDGVWITYNSENLVWLPSEYRPFRSAVSGKTIGIGVNSGKIWMCRFNIENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUS1</accession>
    <name>A0A6A6NUS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mss4-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_380606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUS1"/>
    <dbReference type="OrthoDB" id="406544at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF30">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03180)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="15398" checksum="4D7263637C8AA5E9" modified="2020-06-17" version="1">MIRGSCVCKQLKYEFTGEPQQQVICHCQECRRVTSSAFSINLVVSKETIKIEGSGKTYTFQQKLGPKFQITFCQNCGGTITKEGVDGNMKGVFMIEAGTLDEDFNQTSTPNVEIFIGNRPNWLHPFEGSAQFPEFPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUY8</accession>
    <name>A0A6A6NUY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HypA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_395869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUY8"/>
    <dbReference type="OrthoDB" id="10004862at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="49474" checksum="5555070F7FD888BC" modified="2020-06-17" version="1">MATPSKIVLSPDQKAAYRVEQISPDSAEIASKLLQENHEKYHIFFNQAGFHNHIAHHLLTIFALGASPEVIQRQYDGNKSYQRDQQGADNSVVEDLADPAKFVQYLGPEKYYQDFLLFFRKHMEENGWENTLNEYLFKGDQKSEEMIARLFGGFLHPIIHLGFGVEFQQPAIMCEALAQTAVHGNWMGPFLFGAEKAAKAGRGNVDKPLMEILEEVRTDQNIKTAASWSQGNKMREGTFTYALDEIINHTAQFVATEDTLEEKMAEMIQVNTYFTAAAQRPPHRVKFDFLSMHAVNMTVFFAALLSPRSPVPGRGRARLLEMAARASLALYASRACPALLPAEVASYAPARAGDGWAALGARARGLADDGHAAKMLRALRHAETCCRKWEGGAKGAAWPIRGDMWLKVAHMGMDSVEAGGPHWVRNAGFQEAWDGVPLRDAEAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV60</accession>
    <name>A0A6A6NV60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative asparagine-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_289439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV60"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12452">
        <property type="entry name" value="RRM_ARP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.10:FF:000024">
        <property type="entry name" value="RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034351">
        <property type="entry name" value="Nrp1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23111:SF40">
        <property type="entry name" value="RNA-BINDING PROTEIN INVOLVED IN HETEROCHROMATIN ASSEMBLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23111">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="248"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="347"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="420"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="495"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="613" mass="66004" checksum="42956F5232C2A675" modified="2020-06-17" version="1">MGAPQIDRYAVIHVATTCDEHGVYVTKDSAEVIEVGWILLDAKSLDELYSDSVLVKPVNTPITPLCTSLTTLQWEHVRNAGSFRDAINRIDQFANEHLISKKLEFAFVTLDAWDLRVQLPREARDKSVVLPPYLQHSRTFDLRTEYQRWQQHHPESLPFGSSSLSNICAALEVEPVQSSAPIKHNLPFHLQALAPASPRRAMEEAVTLARVLRGLIAKSQPPAEHPDVMTRPYDARADVRAFLSERSKVLHMSGLPHDTTQSELESWFTQFGGRPIAFWTLRTPDQHKPTGTGFAVFSSHEEAAESLCMNGRALNEKAIEVSPSSARVLDRAQDILTPFPPSKNRPRPGDWTCPSCGFSNFQRRTVCFRCSYTAMQPPPPGADMAYGYYHPGMAPPPHHMPHGPGMGHPRGNPQSSVPFRPGDWKCGADGCNYHNFAKNVACLRCGASRANALPVNDTSLNPMDNPNNYGMQVGPGSMAGPPGPQSFGAPGGGFNSSPGFPGQQFGGPQSNYALPSGLGAPSPYPPPMGGQFPPAGGMPHSGGFDSRAEAAFTSAGQPPSSIGPGFSNNGFPGPADSQSSDPFSFLSAGIGGLSMNNDDGRRNAPGAPAKPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV83</accession>
    <name>A0A6A6NV83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_70303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV83"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="23986" checksum="F33C2BABE5290AA1" modified="2020-06-17" version="1">MYIVHTRLAGSPRLAYTTVPNTGTYVGRAAIRVHPPHHPPHHTTPRPAPPPPTRERAHKTAYLGTVHSRMAPPGAPLPGPSPNRSPRLRRISRGRRGAVHVCRTCLPTYVGPLCTCGVRTYVAGGPAGAGIYTNEKKKTRAAPGGSGLFHVRKRRRGGTHACGGKAALTALASHPSPASNSPTKAFPRGAFFFWSGKDVSPVSRVSNLRSGNVKKKKKNITWGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW22</accession>
    <name>A0A6A6NW22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW22"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="9072" checksum="0597521BEE65C8C3" modified="2020-06-17" version="1">MAPSTWTNGRVFVLARPFVLLRPADLRVLEYAHGCSSLRVRNFTRFPSNDIVFGCAMPGTGIGSWVGGRSRAHLYLCISSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW50</accession>
    <name>A0A6A6NW50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative AP-1 adaptor complex subunit MU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_70579</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW50"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000006">
        <property type="entry name" value="AP-1 complex subunit mu-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="167"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="447" mass="50604" checksum="11B63FD959E37D4F" modified="2020-06-17" version="1">MASAIFFLDLKGKTLLARNYRGDIPMSAVEKFPVLLSEAEEESSAVPPCFSSNGINYLYIRHNNLYLLALTKRNSNAAEILLFLHKIVEVFTEYFKELEEESIRDNFVIIYELLDEMMDFGYPQTTESKILQEYITQESHKLEVQARPPIAVTNAVSWRSEGIRYRKNEVFLDVIESLNLLVSANGNVLRSEILGAIKMKCYLSGMPELRLGLNDKVMFETTGRATRGKAVEMEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTQVKPLIWVECVVESHSGSRIEYMLKARAQFKRRSTANNVQISIPVPDDADSPRFRTNIGTVHYAPETSSIVWKIKQFGGSKEFLMRAELGLPSVRGDDEKGGGMMGGFGGSMGGVVGAKSGKRPISVKFEIPYFTTSGIQVRYLKIIEPKLQYPSLPWVRYITQSGDIAVRLPDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWY4</accession>
    <name>A0A6A6NWY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_288274</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWY4"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="28253" checksum="CA90CDEAA54AB496" modified="2020-06-17" version="1">MEGKGDLIGWGTTGIVQRTSTGVVIKTPWKGERADECRKDMATEARIYQRLGHHSRLARMIDWDPEQCTLTLEDIPNGSLRDYLVNHESTSLSQRLVWAMQAAEGVQLLHSANVIHCDVGPRNFLVGADLSLRIADFSGSSLQGSQASACPGTRFARPDFDWRSPPKVEDDLFSLGSTIYTLITGQAPFRELDSDEVETRYAARSFPDVSDRPCGHVIEGCWTGNISSAQEVLDLLAVELVTAKEKPPSPHKNTGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY71</accession>
    <name>A0A6A6NY71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 90-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_287190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY71"/>
    <dbReference type="OrthoDB" id="202415at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF107">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="159"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="49740" checksum="81B866ABF108B0F8" modified="2020-06-17" version="1">MLSFFARRVSTVAAVTAVVFLIIFFTLLLRPSHIDTLLPSDHFSAPHPLPVPQNTTDGWSFAARRDARNYALSKEQCDAAFPGLYDEIYRAANFRDDVGPVTPEDVDITWRADGVVRVLLYQNQLYIVDARGVARHDYRDRSLAVLHSLNRAVETFPDLLPNIEFSFAVDDMAEPSGNSKTIWSLARLPEKEKQWLMPDFGFWSWPVTGAESYNELRRQIAEEEDYFDNKLPMVMWRGALNVNKERKNLMEITKDKDWADVKDIDWSNKTLLYERLVSMVDHCKYKYLIHTEGRSYSGRLKYIQNCESVIIIPELAWIQNYHHLLVPSGEQQNYVLVEKDFSDLEEKITYLLEHDDEANRIATNSISMFRDRYLTQAAQACYWRELIRSWANVSFQPQLYEEVDSTDEVTGHSSTTRKLRGTTFETYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYB2</accession>
    <name>A0A6A6NYB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Complex 1 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_372185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYB2"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="9264" checksum="5FDF2E12D6948C6F" modified="2020-06-17" version="1">MPRLSGLQRDVLSLYRACLRAARKKPADTRANFIEFARREFRANASIDRKNFAAIEFMLRKGQRQLEICSSPGIRNIVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYI8</accession>
    <name>A0A6A6NYI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Potassium channel tetramerisation-type BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_422324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYI8"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21973" checksum="EAEA9008C4965886" modified="2020-06-17" version="1">MESASEAAFLQRVEGPVNPRQPIQLRVGERTFTTTWGTIYSLDHSIGEEIGPYKDDQYFLDADGDTFAYILQYLRSRVLPIIRVPGTQEYDIHQYALLLADARRFQITPLVDWIQSNLFMNAVTYKMHRRAGKIEDLEVPAQGDGARVRFTPTWFKSDVYVCPRGIPSHRGVPRNCGKQYIVAIVYGWSAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYP9</accession>
    <name>A0A6A6NYP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_321835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYP9"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05652">
        <property type="entry name" value="M20_ArgE_DapE-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF8">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025380906" description="Peptidase M20 dimerisation domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="7">
        <location>
            <begin position="208"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="400" mass="43833" checksum="AA9AA79AF51929C2" modified="2020-06-17" version="1">MRPQILLLGLAALGRTFAQPTQHPLIAHPDNLQAEGTANEYHDDPLLWLHRKLIEIESISGDEYSIGTWLASFLRSKNFTVERQEVEPRRFNVFAYMGDEDNSKTLVTSHIDTVPPYLPYELRSNHTEIWGRGSVDAKACVAAQITAVLKLLRHCSSDDEVPSDSISMLFVVGEETAGDGMRHFSTQKTREYKAVVFGEPTEGKLAAGHKGILGMTIKVKGRAAHSGYPWLGVSANDVLVRATGELMKLRGRLPQSEKYGETTLNVGRIDGGVAANVVAEQAEAMFAVRIAAETPAVIKSMILEALNETATEAEEAGGEFAVEFSGNAYAPVDIDHDIPGFDIITVNYGTDVPNLTGNHKRYLYGPGSILVAHSDHEHLAVEELERAVDDYQRIILATLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYU6</accession>
    <name>A0A6A6NYU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_345811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYU6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="40605" checksum="0F789D002A682CB9" modified="2020-06-17" version="1">MGRPAWPPRSVPSRPPPPPVLQRASADWLLNMSNGNFRRLADRFSFAGLYPGMGPSAAINAVVGYVFFSRHSDSVDWFPGKDPTQPTEPQTAEPRKRLLEGENIEHPERLSFFLRGLLNANDGTELRCSVLIDMIPPSAAAHEVMSLVDGGPEPDGQVYSYDRVNMRVRWPGCTHYHAILVRFMTEEGAAHFFRVSRSKPLVVHGKKCRVAWIPTPTMGLTLGKLHNFTINRQSRSICIREAPDDVSAMVLLNRMRPHGMGPAVEHQVVESIRLYRHLNMVDLVFTSVPEAVRNTGRTTSQGKFVLCKVYYGPDPSCREPQRPSYVHHHGTSLAMPRPAAWPTHQQATPAQVIDDEERLLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZB9</accession>
    <name>A0A6A6NZB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_392121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZB9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22816" checksum="F06A419A926661A0" modified="2020-06-17" version="1">MAALQYKTLPPEVGDASKPQDSVPQTLTLYRTKGLYNSVFFNAEDRLPDHLNRNYGHGPGMEPHDIFGIQNWGVDQITHSLNLLPVLRLATRLLVHKQTLYFWHDILLGPRRPLNGPDAYNCVEIVPGRQALSEQQALLTHHTLKRLAKSIILKVMSPADQQRYGRLSVAIENINPGAHVQDIYGYNRTGVQILIGQRTVPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZI5</accession>
    <name>A0A6A6NZI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_35791</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZI5"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469:SF1">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025447817" description="TM7S3/TM198-like domain-containing protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="8">
        <location>
            <begin position="145"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="400"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="797"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="661"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="687"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="717"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="797"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="848"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1029"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1199" mass="129671" checksum="DC35CBFE15C42E04" modified="2020-06-17" version="1">MRAPYCLALALGFLIFCLSVASASPPHYRLAQRQDDNAASSEAPASTTVVNPESSVETSATSDAQSEESSPTSTREEQSEPSESQSRSAADSEPTETPSPSSTTPLSITATVSSAMAASATNGTASRDGQLPVPPKITPGIGIAGVILLISGLVYTVIGIKNRWMFISFSAAYLCSLAVTVLIIYVMNPPVSDAVQGAFLVAAVITGLLFGGLSLIFQEVTEGLGCLLGGFCLSMWFMALKEGGLIETKTGRAIFIAVMSFTAFTASFSHYTRTYGLIVATSFAGATVVILGIDCFSRAGLKEFWLYLWGLNDDIFPLDTNTYPITRGIRVEIACTVLLFILGLISQFKLWKLIKERRQRKDEDRQNREESLERLESEVGRRIENDITRERAQWEAVYGGKTDGVRPTDSGIGTDENLTKTSVSVRELRRSTTSTMTDSVEMDELGQDGQVPSRRKSTASRRESQEKGGAGVMITVAEDDEIQEVDMTGKPLLSTRGPISRVSTQPSSSNPSARGSMEIRGGIEAGNSRPLSTRSSLRSSVPPPPPIIPLPFKIPQEEDPDASENSSISTVPEDLHAARPKPKRISAASGSKRLSLADMPGESREALIVPHDDDKDSSVAATLDNDNEDRISLPDFTRSNTPIFNPDDLQGEFDATIRKVPSSTSIDGVKSPTDSVQENGLNVISNTGSKSTKSSAAGSPTEGPQVRRISLTTSTDPKPDEPRRKRTSVDSQRRQSGASILRDETEGRRRSKSAKSAAQSEVSRGAESNVGSLMVEHLPRKLSKVAKSYRTNEWAKHLEAAEKPEPEILDKEPESPGIQVETGFQETAAPVEIDGTPQYDLPMASGFVRNQSQNGGTNPYRQSKNGRPASSQSLTGPHVDQQQQQNLPRPASSGNLARSSSQPKLSTRNLRSSSTPLGSYTLLETPAEEGNGGDTSPTTPTNGPHRVSQAPLPGNTLMGKRDSMMRKKMSTMGFSTPNVAATGAVGPNDSASIRNIRRFSDEQPSGFPEEGEASDLEDMTLAERKLYIQRQQQQQQQQQQQQQRRTSSGRAGTWSVNPQSLNGFDSHQPKRTPTVDSVKREQMMASWRESVRQDLQTPQGFVAPQAAPQAAPQAASNPTPLVSGGPSLAAGPKAVPDENRRAAMITERRQTQMAAQQQQIQANMKDEAFDQMMRRGDMLDLHKVAMRRMQAAANKHATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P002</accession>
    <name>A0A6A6P002_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-AMP-activated protein kinase beta subunit, interation domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_392477</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P002"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000562">
        <property type="entry name" value="Snf1 kinase complex beta-subunit Gal83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="5">
        <location>
            <begin position="676"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="313"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="568"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="699"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="588"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="640"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="654"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="809" mass="83634" checksum="61FA3552CBC4333E" modified="2020-06-17" version="1">MAGRANRRRRWPKAGPGSLGCGPRAAAASPANPLPGAAPTPGTSRYEAVDRRQVLPHAGTPERKTPHAATAPLACPRRLGRPTAPVAPPATCQPRLGPRLRRSAAAMGNNPSRSSSTSQPQSPAASASGGGGGGGPSHAHSAPGSNDGGGHHHVAVAHHAHHAHHPFSSPHQYYTHHHHQHHGQPQPAAPHLHHAASAGSPAHRGAGAKEPRRRESIQALTSSAKATAAPPSATLDTAHAHPSSSSAAGGRPAHARRRSQTADQGQPQQPKEGTTSAPLNPVDALYEKMGGDVSAPHKGPAAPAAAAAAAAAAAAGEPQGQDQPVAAAATTTTTTTTTSTSTPPPPPAASPFTAPVAVPGQSAEHAGVAGKDADDDKADFDGAIGSAPEPYPLPPSQYSRPPRLPLPIEEELHTPGSPIISPADLSSPIDPLDVDGVLPQSRHSMLSSTTVEDEDDASFEEGPEAGGPRADIAPVEPRPTVPTLIEWRQGGDKVYVTGTFAHWNRKYKLHKDGPSKHKDALSAIISLQPGTHHIKFIVDGEMRISDTLPTAVDFTNILVNYLEVSIDDVPPPQPPGVPKLSKQPGGRAKTPPAGQAAGAAQKEQPQETQEQQRQHQQQQQQQQQLLQQQQQARAALHPPQMLPPSPELRPAPSPAAAAAAEAAAEGTGPAPKPVVQNLPPKLYHRAIPRFFVDLEAEEEEMAGGEGGGGEGGGGGGGGGGEARFARASAALNAVPLPPSLPMFLGKSVLNGSMPIKDDASVLNVPNHTVLNHLATSSIKDRVLATSVTTRYKRKFLTTIMYRPKGESGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P047</accession>
    <name>A0A6A6P047_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid droplet-associated hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_386006</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P047"/>
    <dbReference type="OrthoDB" id="448051at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37658" checksum="587EC834C2F8D810" modified="2020-06-17" version="1">MTLHPSDAVHLCPVQSSSHDGTRHYLIFFIPGNPGLIAYYTSFLTHLYGLLNQEALRHPAHTISFQVYGQSLSGFEVSSFKSGVHVAHESPPYTLRQQIDLTKHSLEDLVKTLGPAHRVIFIGHSVGTYIALELIRLSNPKVANDVGLKIDNNAARRLSTTRITGSVLLFPTVTEIAQSKNGKRFGYFLTLPLFAWIAAALAKCVATIVPFQLLVILITALTGFPRDAAGTTAKFLKSKWGVFQSLHMARTEMEDIKADKWGEEVWGASAAQDTTPSVPKLYFYFGQNDHWVSDKTRDQLIRHRGRSSNSLDSPGSEERWKPAMEVDQNGIPHAFCICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P053</accession>
    <name>A0A6A6P053_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_39211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P053"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17821" checksum="709A4E387282D61C" modified="2020-06-17" version="1">MKEKEEFALGRIACFAFCRSCVCTWLFFEAFWPPLARTRAQCCGECHSFGSCTGSRRVRNVAPVLKGNRVRPHTACSSRLARELLDPGTFFRASNRCNILSLLFFSLRYRVPEKKSESAQSSASGSVLPGVTRLVRLAFADPQPQKHSVMGHSIPFFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P069</accession>
    <name>A0A6A6P069_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_25232</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P069"/>
    <dbReference type="OrthoDB" id="5399138at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050688">
        <property type="entry name" value="Zinc_finger/UBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24403:SF67">
        <property type="entry name" value="FI01116P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24403">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="11">
        <location>
            <begin position="51"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="9">
        <location>
            <begin position="53"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="13"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="99"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="57333" checksum="86694D4E55CE595F" modified="2020-06-17" version="1">MFLGHDPLAAWDPLNSQPFSELGQPIGSPFLASQEFTDGSETDGPPTAFARRRIPAEARSILEDWFQSHRDNPYLDKKEATELSQATGLTERQVRTFFANSRARRMGGSRPSSNRSSPGPAPESSGATIRSRRIANTSTPSQGSPELNIKLPSRSMASVFPPQRTPSGRQTPGDDDSMSIRSASFQRSSSTARARSRSNSISETPEAAFQSSTPSSTTDIAWGSPSQASIDTAADRAPRRGRKRQRDSILQQTRSIARERVDPQKIFQCTFCPRDFAQKYDWRRHEESVHLPQREWVCMTTGPLMTDPASGFSFCAFCDLPNPPPRHLDEAHNCTACLLTEPADRTFTRKDKLLQHLAQVHKQSAMSRHMAAWERPVQRNVLIKCGICGADIRCWQDRVEHLSNHFGAGQDMRFWIGPPGGILPGDITSGGAGCHAGSTTGTSPPQSRAMTPGVTGGSSQPRITLSPPQASASLFTGGQQQQAPASYTCSLCPLRFPVQSKAIWHERVAHGLYRVQSVHEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P093</accession>
    <name>A0A6A6P093_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_286441</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P093"/>
    <dbReference type="OrthoDB" id="1660966at2759"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000001">
        <property type="entry name" value="Pyridoxine biosynthesis protein PDX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003215">
        <property type="entry name" value="PRK04180.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00343">
        <property type="entry name" value="pyridoxal 5'-phosphate synthase lyase subunit PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="PdxS/SNZ N-terminal" evidence="12">
        <location>
            <begin position="21"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="9">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="249"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="32761" checksum="A90D99FF8ED8A376" modified="2020-06-17" version="1">MATELPTTNGHETQDGEGNNFAVKAGLARMLKGGVIMDVVNAEQAKIAEEAGAAAVMALERVPADIRVQGGVARMSDPRMIKEIMEAVTIPVMAKARIGHFVECQILESIGVDYIDESEVLTPADHAHHVEKHPFRVPFVCGCRNLGEALRRIGEGAAMIRTKGEAGTGDVVEAVRHMRQVNEDVAGLAGLDDAALRVRAKELGAPFELVKRTAELKRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPAKRARAIVQAVTHYKDPKVLAEVSMGLGEAMVGINVEKMPEAQRLAVRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0W6</accession>
    <name>A0A6A6P0W6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_421502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0W6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="524" mass="52193" checksum="9D5CA237FAB97558" modified="2020-06-17" version="1">MIMTWLPVGVLLAIAVVFANALFLPIPSDYRLWYSRLSGSIRDDGKASVSESPPWRSGDGPLIQLHVGAENNDGEPKELELKAKRHPDELSGNDASASTANQFISTIISAVFPGDDDDHDIPYLNGPSMASFPGGCDGFQMATNCGPTNTAAEPVEPESTGFMPESSITFGFQPTTPPPQAPNPAPPQETAPPSTYGAVFHFDNGEVFTVTNIAPDGDVVFGDYTLTPGGPPATLPGGAVVSAASGGLVVDGSTAPFSAIPVTVTPVISAAIFTFPAVGQRGTATLAAGGTILVGDTSLVVGGPAATISVSDVDDDDSDSDSDDEDDNSSDDATVVVSAATGGLVVDGSTTVPFSTLPFPAAPTTTTALAAVLNLAGAPVTASAVSPADPAVVVVGDGDITLSLGGPAVWVSGVQVSVGTAGVVLGGGDTGTATVTLSAGGDGPGLDLLTETRPSPSRPEETGSLSTGAVGDGDGDEGDGEEGAGGAAAGPTASSTSGGAWWKRGRRLDVGSCMVGLAGLWLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P166</accession>
    <name>A0A6A6P166_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_378860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P166"/>
    <dbReference type="OrthoDB" id="5331170at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="31758" checksum="E4AF437C6F5394B5" modified="2020-06-17" version="1">MQYVPVPTPWDPPPLRLPPRRHHTIQPHYAVVWPRDGRNTSTWGRLKDVLTNHGPDMYVSITPTATAVDAPRREQWSGWVDVPVRRGVFGRQGSRAGGVRQESPVGGGSERRRRHNHATRYDSGLTGTFMSGGVAGPAPAPPTPAPTPGPGTAPSPMPAAHAQPRPHSRLTTAVDSDSGLSTDEAAVDDDEDAFSDGEWPPMPWAHRHSAERYDFRTRKYTTEPAFDSNAWRDVRWQPEPNGIFAQPRAYRTVGGQWWEVMELPGWAEAQRRRNGQGRRRRAPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2J4</accession>
    <name>A0A6A6P2J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_363045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2J4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="22751" checksum="BE2670FB2E808324" modified="2020-06-17" version="1">MVRVRSSVPVTVPRRRCAYGSPVRARASSSGYARAQRVPSRLIIAVYGATSCASTTWRPVGPQLQYSNARARYGGHIECASYVVSLAGVTLHAQSSIVSRKGHRLRAPPNASGFRTLPQIDRGRGNLLEASLAGLGSRQSDRSVRRAADQYRVRVLMQTPSPRTTALPYVPVDKSPFRTSHFAYERRPDAPPAIWLAGRSTNRKRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2L7</accession>
    <name>A0A6A6P2L7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_31515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2L7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025556320" description="Secreted protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="19864" checksum="2B71CBBC6D47E639" modified="2020-06-17" version="1">MFPPRCGVPAIPIHNFPLSFLCCFPLHLFASAAAWSYRGSPADACYVFSFVPLCRTQSSPLPPPFFFRSFATDTSSVRDGMTTPRALPRLLRKTCRRKPRNSSNYFNTRGGLGGAAGLGSGSTESEKVGGKKGMRFGLARFSHSLEYHLDIARLLSGLFCESKKRLVHRCPLGFLVLTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Q9</accession>
    <name>A0A6A6P2Q9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_391128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Q9"/>
    <dbReference type="OrthoDB" id="5345494at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="59920" checksum="8A222CC316C3EF9C" modified="2020-06-17" version="1">MAQPARTPSSQSAPSITLPDLLHNSLILRQTAPYLPASAIYALARTCRTLHSLLLQHSASDAFRHLDLAPVRSAAAALRVPIDRGGNTWRAERMDESLTEDEFYSGPLLGIFSKLGRGGPRSGPALRHVQTLVLDGLNSVTADLVREIVAEERFASVRVLSIRECENVNERKLMGVLRYAVRPTRAEGTPRLKALYVFTPREKGGGTPGAVSAEPKKEYRRSPERSPERYLMGASSGSSPAGSASGGSNTAASTPGATHVGAEWNARSQEALTAALARTDDRWYQASGRMLKRQPAAEWAETLRVCEGVIAFDAVLCRGPRHDPDWALAQEAASFSASSSASSSASSATSGASSAHAAGVGGRDAGANPLSYLPPAVATVALGPAGCDACGTCIEGPARFGASPASHLPLLGPPPLHGSSVRSAQMPHALDGAAPAALPLIVRCEDCLRGRWCERCNKWWDEACYGGAGAAGGGAATRTHLQQTEEALEGIRVAGLGAGRNNGLAKMGVKRECFGCGRVCSECKDRFIRRCRTCYNEYCIIDNDASSETACDWCNFSGRRTRELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3T0</accession>
    <name>A0A6A6P3T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_370701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3T0"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="15"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="466"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="680" mass="74825" checksum="12A1A54FD75C5B23" modified="2020-06-17" version="1">MTTQEPYTLDLAGRGFIQGLTFADEATGAPIAHRFGGLPYAQPLAGRPRWRRARPLDDAFVYGTRERPGSFAGQCTVCPQPSFDGSSVTHGCEENEDCLQVNVWVPAGAEPGDGWPVFVYIHGGFLQMGDANGLNPLHLYAETDCKFVLVEPAYRLNVLGFLASKELQEEAKTDGDETVGNLGFWDQRLALEWTRDNIELFGGDPDNITVGGYSAGSHSTFYQLQYDLFQPDENSLIRRAIMWSNGPGVQPKSMREAQAQFDWLLKAADIPPTISSESKLARLRAMDPATLILASTSTPLHEYRATTDGAFVRPDLFAAIDDGRFAARMRRRGVSLLTGECRDERFLYGTYRPAKEDSLPALLDRLDADYGPRAVDALRRFYFPEGRLPDSMEDWRSDAFGKVYSAMQIYATERGFIAGLVRGGVALGAAEEEGSRVTEKARDEDVVDSISDAEFDVVAGWGGEEFGGAVHGVSGEEEREEGAEQEQRGVEDVETEHHPNEHGDDDVDHVDAQIPLMLDENRHRIGKQSEGNPRRKGPGSSSSPGAALAPPRPHSRLFRYRIDFRSSVVHDNPTWGVFHGSDMTLWFLGMTATLPPGEKALAREALVEPLGRYLRGEDPGWGVSGRDAREMRRVTSEGTVDIWRDGRWEEGVGLWEELRRAGVAAGEGSGSGVARGGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P497</accession>
    <name>A0A6A6P497_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_301630</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P497"/>
    <dbReference type="OrthoDB" id="204980at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11319">
        <property type="entry name" value="AmyAc_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000120">
        <property type="entry name" value="Alpha-amylase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013777">
        <property type="entry name" value="A-amylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015340">
        <property type="entry name" value="A_amylase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF215">
        <property type="entry name" value="ALPHA-AMYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09260">
        <property type="entry name" value="A_amylase_dom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001024">
        <property type="entry name" value="Alph-amyl_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025357321" description="alpha-amylase" evidence="18">
        <location>
            <begin position="25"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="19">
        <location>
            <begin position="37"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="13">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="14">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="54"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="264"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="467"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2458617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="504" mass="55726" checksum="219033952648B3A2" modified="2020-06-17" version="1">MRLQGSTKTAAAIAVACCSVGVHAAGADEWRSRSIYQLLTDRFARTDGSTTAECNTEDALYCGGTYSGLIKKLDYIQDMGFSAVWISPPVKNLEGTTAYGEAFHGYWQQDIYSLNPHFGTPDELRELSDELHDRGMYLMVDIVVNHMAWPGPADSVDYDDFYPFNSDSYYHSFCDITNYDDQDMVEDCWLGDSNVELVDVKTEDENIQQMYNEWIAEFVANYTIDGLRIDTVKHVEKDFFPDFLDAAGIFATGEVFDGDPQYVCDYQNYMDSVLNYPIWYPLTAAFQSTSGSISDLVSTLDLIKDTDTCGDPTLLCTFAENHDVARFASLTSDLSLAKNILAFVLLSDGIPIVYAGQEQHYAGDEDPDNREAVWLSGYNTEAPLYKMTATLNAVRNLAVTSNSSYLEYRNWIVYSDESVLAMRKGYDGIGQVVTVLNNQGEDGGEYDLSIGQTGWEEGTSILEVLGCVQATAGSEGMVTVAMAGGEPKVYFAEDSLRGSGICGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4N4</accession>
    <name>A0A6A6P4N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM8</name>
        <name evidence="11" type="ORF">BDY21DRAFT_370475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4N4"/>
    <dbReference type="OrthoDB" id="422364at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000027">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="98" mass="10817" checksum="FCA53C09EF6F7936" modified="2020-06-17" version="1">MSLYPYVNKKVLVITVDGRTLTGTLVSCDQVTNLVLSDTVERIIRPADDPEPSSETSHGLYLVRGDNVVVCGLVDEELDKSIDWTRVRGDVICSTKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4P8</accession>
    <name>A0A6A6P4P8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA ligase/cyclic nucleotide phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_283040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4P8"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="40762" checksum="62F6AF0A80432C07" modified="2020-06-17" version="1">MGSNTNSARLFSFPPQQPGDTNIKNWYQDLIDDPNCQGDPAKIQEAYTSFRQAGLSKSIAALLPPDPPDNESKDSFQTAVSNSASASIIPDAALIKHLSYRRTSIEEDELSTHDVNCLVIWARPTAQVLELLHDIQQKLTTLVGDDLYPIRAVDMHLSVLELSHRHSVSHLRFVYAQVGNHRLQKMLDLPFTLASGSGNPDGINPSAGPPDSGKPNGIRACLVEPQVMFDAKGVAVGFVPAARPNEVDSQFTYNHLRASLQNHALESGVEIDTCYTAPLAHVTIGRFVGNKWFGGDDAALGNMKRERMQRWVEEIENVNEWLRRVYWEDKKRVKWVVGAEKGLEVQLGYVKFGRGSEDADLVGRPVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Z3</accession>
    <name>A0A6A6P4Z3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_339751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Z3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="22701" checksum="EE482B303FE465AD" modified="2020-06-17" version="1">MGRVARELEELEEAKREAVKAGESRRQRGERERREAKVRRYMDFRKRVEKRVAMEKKRGPLLPEATATTAFESAYAMAHQERIKFLRRQCLQRNDPVPRYLGEWAVLEQAFSHVYVVDVKEHFDELAEVAGRAILWEPINGETGVGVHYVYPKGSKGLKVVKWTDENGKEYTKRVYKPTKSRMNEAETAEDSEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5M1</accession>
    <name>A0A6A6P5M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_200639</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the xlnR/xlr1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5M1"/>
    <dbReference type="OrthoDB" id="5365785at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000004">
        <property type="entry name" value="Xylanolytic transcriptional activator XlnR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="115"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="58"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="986" mass="107698" checksum="E450780EAAB74D23" modified="2020-06-17" version="1">MLSTSLHQYPPAFSHMQSPDMVNHNHHHQHMAPQHMPTPGLDSLAHSSHYALQQLHQPHQPFPHNRPFIKQRHHPYGNGPLNPAAAAQRNAMPTDQRPGRATAAAGPVRRRISRACDQCNQLRTKCDGKNPCAHCIEFGLTCEYVRERKKRGKASRKDIAAQQAAAAAAAAAANGTNGASENSNGVQSTPTNGVTSEDQNRAGTPQGIDRQSESRGSINDRPASSMAPRSASMSSTQTMNSHGIFNGMSATSRAVSMSGVEAIAENGMHPQMPNDASGRLQNGSSMMGMPDFASVDEYGRPVMPSNGQHMMHHNVSGPMPHPIIPPSSIQGYGESPYSMLSPQSQSGHPGFRLGTEESSLSGFLGSSPVAGSPGWLSLPSPSTTLYAPHHSMPASQALRYPVLQPILPHLGNLISTSLACDLLELYFQSSSSAFFQPLSPYVLGYVFRKRSFLRPNNPRVCSPALLASMLWIGAQTSESPVLTSSPSARGKICQKLLELTVGLLKPLIHTTSSDLGSPNYEANTVVNGVALGGFGVALPSRAQDAERGSPGAAGDLDDVATYMHLAIVVSASEYKAASLRWWNAAWSLARELKLCRELPTPNPSNRPAEPGDEDADGEVDLEMNVQNGSANGTSNTPGEISEEEREERRRIWWLLYIMDRHLALCYNRPLFLRDAECDGLLQPIDDNIWQSGEFYSGDAEPNSQLFRRKGPIFECTGHSIFGYFLPLMTILGEIVDLVLARNHPRFGLRIRSSDWDEQASEIREQLDSYGRSLREFEARSLNGHSDSKADLSSVMEGVRDHSSPSGGQFGKNTESLLHTKMVVAYGTHLMHTLHILLNGKWDPISLLDDNDLWISSPSFMDASSHAVAAAEALSDILEHDPDLSFMPFFFGIYLLQGSCLMLLIADKLQGEASPSIVKACETIVRAHEACVVTLNTEYQRNFRKVMRSALAQVRGRLLEDFGEQQLRRREVLSLYRWTGDGTGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5W7</accession>
    <name>A0A6A6P5W7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_338125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5W7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025468598" evidence="2">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="86" mass="9055" checksum="31FE9438B35C4796" modified="2020-06-17" version="1">MSSLFSYFLVNAATVIVAVSCSDEQLCNSNSTLIERPSPWSFNVETVVTLVLGSIGTILAALNVVVAWRQLVAITRIAAVGGLDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6L4</accession>
    <name>A0A6A6P6L4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_191920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6L4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="12894" checksum="1BA03D841977E784" modified="2020-06-17" version="1">MAQMCLQLFHIRSGHRTSFWAVCLSTVEYTFVHGFPICAFQLPLCGPSASAIALELFILSIYSVVIGNGPLYIRLGISLLSLPVTMVALLGTCLARWCQLTITTERLPGTNDACFLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R9</accession>
    <name>A0A6A6P6R9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_201660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="28"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="37374" checksum="BE96E2AFBF7796BB" modified="2020-06-17" version="1">MDGKSIGKKQSEELLSSLKKLFDTQEYADFTLRCRNDKYNLHKAIVCPRSKVIARALDGRFEEARTSEIDFKEDNPQIVRRMVHYFYHLDYPTVLPAAPESGVDTALEDIFAQNSAAPAEVPPPIEEPLAEEESPLPEMPDEPAPWPELEPAPDPYDAGEEYIPASAGDQSADDVELAAAVEEAREAVAETPAAVEEAXEAVAETPAAVEEAPEAVAETPAASILSVHAKTYALADKYDIQGLKALAVDKFSVALQNHWNDPDFSQAAEIVYETSVPEDRGLRDLVVQTLHRHESIADKDDVKKVLKRVGDLSFDLIMYVRAKGGWESHEPLEPEDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7A9</accession>
    <name>A0A6A6P7A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF962 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7A9"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046521">
        <property type="term" value="P:sphingoid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="200" mass="21803" checksum="7094482324DB1615" modified="2020-06-17" version="1">MALNLERQLEFYGSYHHNPVNVAIHVTCVPIIFFTALLFAANTPAFPLPDALSIPNLPANLSTASAFLYAVLYILMEPIAGGLVLPIIVSGTALVNYLLQIYGATANYWAIGLHVASWIAQFVGHGKYEGRSPALLDNLVQALFLAPFFVWFEILFNFGYRTELKSRLDKAVEQNLAKFNEGKGKKAATNGAANGSAKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7I2</accession>
    <name>A0A6A6P7I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_336983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7I2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="57" mass="6322" checksum="A043F72A2411E910" modified="2020-06-17" version="1">MLACLTRHQKIEHRHYSSPCLCTGACLLPTAPFSRRLTLNPRRQMTSLAYAGGGSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L0</accession>
    <name>A0A6A6P7L0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_190180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7L0"/>
    <dbReference type="OrthoDB" id="4149149at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="461" mass="49159" checksum="13F44E214BAFDE9A" modified="2020-06-17" version="1">MFNTNHPTAPIPSQIRFRLQHLKLVTLFTRRLPRDSTSSTTSPSSLASLRRANSRRASRRGVPVPPPLPGAPSSTTTTTTNSTQPDVDLSSLPLPPARLSRNRRAVLADLAAVPDPEAPEAHDLARSYGSEALPALLDLLPAFMGLTAARVRLGRDGSYGGSPSSSPEPTRLGKENEGDGGAVAVAELQQQRQGRHQHQHQHQHQHQHQQTGGPRGVKRTSSPSSQQPQQHQSSQGSVGSIVDLPPSDWDISERWMRLAGEWMLQAALEQYLVVGASGRAPLEEAFAWGPGCKKSRRGAMSRGRSGAGAVGENGDVAMNGGGASAGVGGFDGGDEQQLAEEEWAIHCMFGGGHRAGGEIAAQWEEYRRLWYAKLLQKSTAATNTPSNGGSAATPPPDYHPLEAVALAHPIAAFEADALVFLDRLLKSVPAPVLTQLEIGQLNGLSVPETEAFKSRVGFPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L7</accession>
    <name>A0A6A6P7L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_178559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7L7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="150" mass="17095" checksum="E711EBDD8D481022" modified="2020-06-17" version="1">MQQQLSNAEHEIHFLLSYATNRSTMTPLSSSSPYQNKFAQIKQLFLERQYRKCATRCDELLAGSHQDVSFIFSTVLASPASCCFILCNSLRLDRIMPRAALTCSRYILSTLHILLSTRACHMMCSLVASLSIHLPAFQHWTWRRSTTPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U2</accession>
    <name>A0A6A6P7U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_337348</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7U2"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="17674" checksum="D14AAEDFD29D9019" modified="2020-06-17" version="1">MADTEYNAEEAAELKKRRTFRKFSYRGVDLDQLLDLSSEQLRDLVHARARRRFNRGLKRKPMGLIKKLRKAKQEAKPNERPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P893</accession>
    <name>A0A6A6P893_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flavin monooxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_337212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P893"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025650544" evidence="6">
        <location>
            <begin position="25"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="523" mass="58118" checksum="51E014BA731B39A2" modified="2020-06-17" version="1">MGEGTTVAVIGLGALGLVSLKNLAEEGYVVTGFERNGYVGGLWNYTEEDKTSVLQSTIVNISKERGCFTDFPFERDVSSYPSAAEVQAYLLNYVDHFKLSPNIRLNTCVKQVRRDQVRNKWALDIEGAGPEHFDKVVIAIGMNSIPNIPVVEGIESFGGVCVHSRAFKRPDDFVGKKVLIVGLGNTGADTATSLIGYAEEIFIAHREGTIILPRVVDGKSLDHSVNFRLTKLQDFMNDHFPDFAEKNLNKFVKKIQDKAFTIDPKWNLSPAPSLKQSVPVVSDTLVTAFESGSVQPVSALRKVVQENAVELADGTHLAVDSIIWCTGYKTHFGLVEDEYDPTKRTTAQWAASRGSNGKPLPRLYQNIFSLERPDSLAFMGTVAFPNPAFQIYDLASMALAQVWKGRSSLPSRASMEAAVDAHHEWVCGLARRGSVYPGIVKPQEWMRWVNEAAGTGVDEYLGYGWKGWAFWAREPRFCNLLMTGIYSPHVFRVFDGKKKKWDGARLAIERANEDVKMKKVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8H6</accession>
    <name>A0A6A6P8H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_185086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8H6"/>
    <dbReference type="OrthoDB" id="2932980at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="374" mass="39114" checksum="DB231F437D1097FA" modified="2020-06-17" version="1">MSTGYFHNRTKTYLDDLWTGLVTASHILHHHSLLPDASNISVRNPDNPDSFFIPRSASPVQLSASSAASALLELNISDANPVPRTSSSFPDDAERPDPPPEDCLPAERHIHASLYARFPALTSILHICACPPTLTPFLISASPTSTSSSSSSSTPHIPFTTTSPADPTPLLPLRPLTLHASSALAAPAPLFDPSALASAHDPFLRSKAAADALAARFARAETSAGFLAGKLRGAWAGGFGASGAGAQDGGAKEAEAPARSVVLLAKGHGGVVVSCADGGLEEVCWRGVGVVEEAGRVREGVAVVGAVGERGMGGKKWDGEGKLKEGRVMGVGVEGLGWLGEKECAEGLSMEGERVRMWWEEWRQRASREGIYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Z2</accession>
    <name>A0A6A6P8Z2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_160739</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Z2"/>
    <dbReference type="OrthoDB" id="5357315at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000364">
        <property type="entry name" value="Protease-associated PA domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051653">
        <property type="entry name" value="E3_ligase_sorting_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168:SF1">
        <property type="entry name" value="OS02G0798600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168">
        <property type="entry name" value="RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025613581" description="RING-type E3 ubiquitin transferase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="608"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="759"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="132"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="313"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="390"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="655"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="872"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="535"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="661"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="720"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="883"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2460287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="899" mass="94547" checksum="FF97DEB49ED8498A" modified="2020-06-17" version="1">MRPLRLLLSLTSCIVAITLLLYLGLPSEAAEDGFVGPNGASASGSNHGKKHGKLRALFSFHSPSSLFPPSAIISLTDDNSTFFLARPAAFGPQLPNKGLSGQLWVGSGFGDDSLGRGGGVATGAVGELGCSDIPGWDDGTGHAPGGGDAGSPRRQMAKDASGLEGSSMKRRDTTPRDDDGVDSTEGDDGTDDHLHDPLAGSDPASGGTPGSADGATTPEHADIQSLQESAEIAGKVVLLSRGGCGFLAKAKWVQSRGGIALIVGDDIRGGPLVTMYARGDTSNITIPALFTSHTTAHLLSSLIPSGGLLEGTHAHPTGKLGLEGAKKSSNGKTDGNSPGHSNSRGKSSTRPQESKSRPAPGAGKPSSPSVNGAEKRGWFRSLLGLFGFGHGSGSSTEGDSRRPPSSGNIDWVLLEDWDDDEELPASRPKQTSKSKASPKPSPTPAAKSGDDFVIGVQDWRDPDLVEGADDNEPVNGATQNSQSSGDQNSQDSNHPNGGSILPGSGEYEKPGSEPSDSSSGRTSPASSLGEDNEEDSHNDGWLDHLLGGDDHEDGSTSSKSSSHSHQNDVPVHHAGGAHADEHSSEAHDGLWVTLTPTGMSSSPFFDTLLVLVVSPLVTLTVVYALLLLRSRIRRRRWRAPKSVVERLPVRTYHTLSSNEATTTSSPLTTPVTTNPTTPLLHHSSRAAVARPRPRSRTTSEVPEQIISTASTSTTAASSYRNDRPCVERLESSSSSSEQEKRDSGLAEWRRRYGGRQKECVVCLEEYIDGISRVMSLPCGHEFHAECITPWLTTRRRTCPICKGDVVRSMARGDTFGAGSPTAGYDDSDDVQAQAAENRNDSPSAALPLLHEADEFDADVERAEASATAAARGLGSFFGGRGGDSIRREHQLHEEVDRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P965</accession>
    <name>A0A6A6P965_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_335363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P965"/>
    <dbReference type="OrthoDB" id="63070at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000557">
        <property type="entry name" value="WD repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051859">
        <property type="entry name" value="DCAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847:SF7">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="423"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="665" mass="74287" checksum="B1106E6850F8B5E0" modified="2020-06-17" version="1">MSAGQSPAGGGEDETHLGDRTMARALGIEGLLDSGELDYRPDEETDDDEYEDVPDEEEDEEFRDAEDGLGNVEVEFEIPGDEESEGAVGGEGERQSRGTTHLNATHNQIIQALLSRAGFLHFTRQGGTAYDEDSENDTGYGGVRTRRGRRKGPYGRSAFEKVPSEAGRGVMEAGKFGTNERLQGTYTRKRKIAYRLAQRELANGSRGQNQSWNGLIKQSMIPRSMADMIIHYNSRCYSGQFSDDGNFFFSCAQDLRVRMYDTSNPYDWKYYKTADFMGGRWTITDASLSPDNRFLAYSSIQPQACLASTDPYDESPPQILDFVSTTSRAQRTQWNYYGFGIWSLRFSGDGREIVAGTGDDSVYVYDVELQRSTLKIPGHNDDVNAVCYGDKMSPHVLYSGSDDTTLKVWDRRSMGDGRPAGVFFGHTEGLTYVDSKGDGRYVLSNAKDQTAKLWDLRKMMSAERADQIDPANYTTNFEYRSSAYDEDSWRPHPHDCSLVTFRGHSVLRTLIRCHFAPPGSADSAFVYSGSYDGSVYIWNMDATLAGTVDVFKATKGTRPRDSRIAGSYDFIESPTGVWQTCVRDASWHPSAPVIAATSWNGWGLNGGTCTVHSWNDGGDEDEGEPKSVRVNDCLEHDEGLYTGRYPSRRSRFSRAARRMYDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H0</accession>
    <name>A0A6A6P9H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIE subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_335802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TFIIE beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H0"/>
    <dbReference type="OrthoDB" id="5323195at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016398">
        <property type="entry name" value="TFIIE-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="9">
        <location>
            <begin position="25"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="254" mass="28905" checksum="1F6A24F4DAA491B0" modified="2020-06-17" version="1">MATPPASALSTMKRKRPFDVPTAPASQPQDANTGQNIMTQVHFAVEYLRKKDKAMSFKDIITYLSIPVDQDRDSVAKTIRRILRTHKRVEYDKDGFNGQGSFRYRPVHPVRNADELKAYLQSRPTAQGIPVRELKEGWPDAIQAIDGMERKGELLVTRMKKDNVPKMVWQNDPTLSQPLDPHFKAMWHTIPLPTNPDELRMKLESAGLKPTSAPNANLLAPKPKEKKKKAPRRGGKQTNTHMLGILRDYSHKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Q1</accession>
    <name>A0A6A6P9Q1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_335874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Q1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="116" mass="13136" checksum="2F60BAA95076F541" modified="2020-06-17" version="1">MSPRSPALDSARPAGPASYFSFLPPRSLTSSFRFDSRHRSALQRGEPAILPFPFALGACRLRIDAYRRCPRRVQCASQAAAQGSVTRIRWDSSELARRPQLCAHRPDRRRTRSRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAU1</accession>
    <name>A0A6A6PAU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="18">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_334148</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="function">
        <text evidence="17">This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 18">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="18"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAU1"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000031">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF346">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 18" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 18" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 18" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="495"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="995"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1037"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1075"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1107"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="195"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00059328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2461046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1202" mass="130743" checksum="2EA14A9AA250021E" modified="2020-06-17" version="1">MSPPDFHQQAHDRGLSVPEINVISDSGDSHNDCDTVVPSIPPSPASRERSLSASNADFPGRKRSLSGSTVGTASSTHLVLPPPSSSGASSSTASLMSKGDIEDALRPDPGTEAAFNVERNPFAFSPGQVSKPFCPKSLEALYALGGLPGLERGLRTSLASGISVNETTLDGTVSFDEAIDYSRKRRRLEAGLGGEKHHLNSVNTSHSTVSSSEAFADRIRVFKRNVLPAKKPTPLWRLMWQAYNDRILLLLTGAAVISLALGLYETLGISREPGEPMPVDWVEGLAICIAIIVVVLVGSLNDYQKERAFVKLNTKKEDRQVKVIRSGKSIMTSVHDILVGDILHLEPGDLVPADGIFISGHNLKCDESSATGESDQLKKTGGDQVFRLYESGHSDPHDMDPFIISGSKVLEGVGQYVVTSVGVNSSYGKILMAMRTDMVPTPLQVKLDGLATAIGKLGTAAACLLLFVLLIRFLANLPSNPSSGAEKASQFMELLIVAITVIVVAVPEGLPLAVTLALAFATTRLVKQNNLVRVLKSCETMGNATTVCSDKTGTLTQNRMTVVAGTFGEDMSFDDKNRTSNERRSTAFGSDLSKEWKDLLIESIAINSTAFEGEEDGKPTFIGSKTETALLAFARDVLGMGPVSEERSSAPMIYFMPFDSGRKCMGAVYRIQNGNYRFLVKGASEILLGFSSTLRTSSGTTDLDPYQKEKLDGVIRSYAEQSLRTIGLVYRDFAQWPPAEATPPNGDSEELALDRLLANMTFVGVVGIQDPVRPGVPQAVAKCIDAGVAVRMVTGDNVVTAKAIATECGIYTGGMVLEGPKFRTLNDQEMKDVLPNLQVLARSSPEDKRILVTKLRELGEVVAVTGDGTNDGPALKTADIGFSMGIAGTEVAKEASAIILMDDNFASILTALMWGRAVNDAVRKFIQFQLTVNITAVILTFVSAVSNDEGHSVLTAVQLLWINLIMDSMAALALATDPPTEQILDRKPIPRSAPLISITMWKMIIGQAMYQLAITFVLFFAGEQILGDILGNEDRQLMLNSMVFNTFVWMQIFNEFNNRRLDNRFNVFQGIHRNYLFIGITCIMVGCQIAIAFVGGQAFSIDRIDGVQWAICIALAAFCLLWAILVRLFPDPLFERIAKFVGRPFVFVYRPLNRWTHKLGNKIRRRKRPGSLREGNIMDSVRLSDAHIGNKERMDDIERDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAY8</accession>
    <name>A0A6A6PAY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAY8"/>
    <dbReference type="OrthoDB" id="79687at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14011">
        <property type="entry name" value="PK_SCY1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF6">
        <property type="entry name" value="SCY1-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="914"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="988"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1056" mass="108564" checksum="F77B69809CB8F07C" modified="2020-06-17" version="1">MFSNALKSFTSNISSNYTLSPHPSSTSGPWKIFDAKKKSTGKPASVFVFDKKSLDPHSGAGGLSSRSGASALKHAHERVVEQLKKEASSLARLRHPSILELVEPVEETRNGGLMFATEPVTVSLAGLLQDKDEQEQRGGGGLGGGRASRYVVEDGGSGGDGRGGRRRRELEIDELEIQKGLLQVGKGLEFLHESAGLVHGNLTPDAIFVNAKSDWKISGLAFSGPPENSTKPTSAVPISLAEALNYDPRLPRFVQLNIDYTSPDFVLDNNLTPAADMFSLGLLIVALYNSPHRSPLETNMSVSTYKRVFASSATIPTQGNNFKSARPLPREVVAGLLPRLITRRPAQRLSAREFQQARYFDNILVNTIRFLDALPAKTPAEKTQFMRGLPRVLGQFPKSVLEKKVLPALLEETKDRELLALILQNVFKIVTSMPSGRRAFEERVVPKLREVFLGGTGGGAQGKAVAERDSAKEAGLMVLLENMGVITENCSGKQFKDEILPILFLALESPTHSLVDASMRSLPVVLPILDFSTIKNELFPVVSTVFAKTSSMGIKIRGLEALRVLCGGGSAEADTDAGDGLDGLSPETSSKAASAKSAANSAILDKYTIQEKVVPLLKAIRTKEPAVMMAALPVFRRVGAIADADFLATDALPILWSFALGPLLSLQQFQAYMALIKELGARIEAEHTRKLQELSSAAASPPLVGTAGAASSTQDFLSFGGPTASTANGSANGDDAAAFESLVLGRSSATAADPFDAGWGDASSGPPSATSSSFNNAAGAGAGARPTSGLAMHGSRSFQGHNTSSGGGGGGGGAPAFSWSTPEPSPGLPGGRSQGAGTGMGMGSRAITPDFSQPLAPQNATSTFSMPLQPSRPAGMAATPAPSSSSSGLNWSGAATGAGGSSSDIWASAAAAGGGAAAPAPAPQRTASNPSFGSAMAAAGSNPWVTAQGGGAGGGGLGGLGGVGPAGGGGTGSPYSGFSIAPPPAWKQQGGQVQTQTQGGGLSGMGGMGAWGGQQQGQGMGMGMGMGLGQQQGQRQGQQGGGGGGKTGLDKYESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB62</accession>
    <name>A0A6A6PB62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_334466</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB62"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002167">
        <property type="entry name" value="GDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00928">
        <property type="entry name" value="GRAVESDC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="111"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="210"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="372"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="463" mass="50437" checksum="28C344A0BD6365F3" modified="2020-06-17" version="1">MPSRISAGNEAPQRQSEYAAPLFSTSAAQQKHDNTIGFDKRHGAISDDSDSMAHQVTPASGSRAMPKTAVCPTDDDSMVTTPRDGKAQLQQRQPLQQKAKGRMKTDRQSPEYMVKSGIAGGLAGCAAKTVVGPLDRVKILFQASNPQFQKYAGSWSGVVRAIVDINRTDGIRGLYRGHSATLLRIFPYAGIKFFAYEQIRALVIHGPQHETPVRRFLSGSLAGSVSVFFTYPLEVIRVRLAFETKRTGTQRSGLVSICRKIYNERPPRVANPPHVHLGKGAIAHAAESSFDVASSAVQHVTPRVGLANFFRGFTATLTGMLPYAGSSFLTHDYVGDLLRFPRLAPYTTIPRSASTTQDVVTGESKTKKPAQLTAWAELSAGGIAGFVSQTASYPLEVIRRRMQVGGVVGDGHRLGMVEVARRIFAESGWRGFFVGLGIGYVKVVPMAATSFFVYERVKWWMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB74</accession>
    <name>A0A6A6PB74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_278722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB74"/>
    <dbReference type="OrthoDB" id="4114825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF1">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="172"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="236" mass="27060" checksum="AB79B328A112E9A2" modified="2020-06-17" version="1" fragment="single">MERSRRPASNAGILKTPRRGPHVKRWDGKNRTCADWDGLRRDSELFFQNGDILVHLYAKGNSRRGPTFRVPFETLQKFNCGPLFSICFAQLLPELQGSSPTGSGRPQDKYELYIPAPDHVPRDDAFSWHITTRNFFALVYRKPLVGTTMGKALVTLHDRMRMFRAKRANNHNDLLVYLEEMGYLNFAHHPDYALAVLYYAEQYQIFGLWADAFVHCVAMNDGLYLSPEFAAISPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBA7</accession>
    <name>A0A6A6PBA7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBA7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17772" checksum="6997468942C936B9" modified="2020-06-17" version="1">MVRIMRVKRQRDRERESTRVAPASFVPCILHSSRSAVPRRRRCGVIATCAPHAVEDGPSGWCHTPPVSAEAWLRATRGHYGGSAVRTGWTGATVIRDGRKTSRLSYDGARARQEKALLLPFDASLRLLCDVQDATYREQRQLRRIESPRPTAPSQQAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBD0</accession>
    <name>A0A6A6PBD0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_130503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBD0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="18299" checksum="9BCE47F78B0E046D" modified="2020-06-17" version="1">MFFHGRLAMPCAIPSIHIRDRASWGLEGPGTDYAFPISCRTCLRGPSRRAVAAGPTDATGPSCPLLLSAAVDVRVRPWTQVSGLRKLLARRVAQCPSVQGRPDRVLTCHVATQAGGGRDFSVLQFKSWARRTKCAGETQPFNRSINLLVGWLCCAGPLPQSKGSRPFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBF0</accession>
    <name>A0A6A6PBF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase-like protein activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_383829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBF0"/>
    <dbReference type="OrthoDB" id="10261121at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="334" mass="36766" checksum="9CC9EF36746A3B2B" modified="2020-06-17" version="1">MADEDRRSFGRKADKGDSRRDGQQTPSPTSYTGSQTSLPGISAPQMPHSPALSAAMSVESQSSEFQASANRKPPFFFREEYAGLIVKGNFMTLAAKPVHVEEGEWLAHQVVEQFRLLEGMLAIIKVIDDRTGKPICNQETCPTMSAAGHTYAWLDQQRKPIKIPACSYIHHVQKWINGKISDPNLFPTDTSFALPSAYASGGMNTPGASTPIPAGPTNLDASLNSLAGKEWLGRSSGFPENFEGDIKSIYRQMARCYAHIYHGHWLDPFWHINAYKELNTCFIHFVNVGKLFGLIADKEMEPMQPLIDLWQEKGLLPSAQQTGSRPEAGQGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBW8</accession>
    <name>A0A6A6PBW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Golgi matrix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_87507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBW8"/>
    <dbReference type="OrthoDB" id="425925at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019459">
        <property type="entry name" value="GRAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921">
        <property type="entry name" value="MYOSIN HEAVY CHAIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921:SF2">
        <property type="entry name" value="THYROID RECEPTOR-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10375">
        <property type="entry name" value="GRAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="6">
        <location>
            <begin position="337"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="403"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="196"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="492" mass="54692" checksum="9B605F6A9A48A8B4" modified="2020-06-17" version="1">MPSSGNESKGGPRSGPDGSLSLSQSSEERWDALAQERDSLRAEVTQLRQSLESIQGKHEREMSGLQEQLDESVEGRERAETQYRNLLGRVNTIRDQLGEKMKADKEELAEAQGRIEELEEQAQSMREANETLTADIDKLRVENEQQAKEIASLRDRASLSQQNWIKERDELISREAYAREEFENAKQAMQDWEVLAMDERSARESLVDRVAELEDRLNTQQEAYERAASERDAQSSTVDGLQRALQDIQDARKKELREVVENSQSQLEELRKQLQAAEEASAAAQATLESTQKELERARPFEKEVKEKNLLIGKLRHEGVILNDHLTKALRIIQHRKPEDNVDRTIVTNHFLSFLSLDRSDPKKFQVLQLIAALLGWTEEQRERAGLARPGASAVGSASSLRIPMSPFRRTPSTPALSSDMFPDSATPASGTRESLAQLWSEFLEQEAQEGGAAGSRRPSAASPSSSSRERGSSLGLGVTPGGTGQPGPGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCA5</accession>
    <name>A0A6A6PCA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCA5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="44494" checksum="C6DB512D3FB92ECD" modified="2020-06-17" version="1">MSVDSSDMGDNTGFGFRRESSGGLPSLSSHPPFYANQRSYVLQPIDELFHLQERRGSTVSTAALSSSSGSGSQTEVQCSTRASSVCRTPLFESAAATGREDQEDLAVQLVEHSPTFGSPNDDDVAASPKSSTRSTDAFESLHRVEAGRVRKPAPLTKVSAANSANFSPSPAPSSSRRSYRLPGGAQEPATDSLSRSSSTDRLGNSRRNASKSNSNNNDEPVSASEREKKRKTEKAIKERVLRAKQRGRNKEIEEFLTQLGSAPQDPLNQANAKSSGCRATKISIMDTAIDYVRALAQDKLCLEEQLKELSIMATGLAEARKAGGDGMEVERRFQALLREKDARFAQTWRELEECRKKNRVLVDDNVQLVKTLEAVQMDSVGGMRWLAVCSSGSRRGPMKSDKVRQGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD71</accession>
    <name>A0A6A6PD71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L31e-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_93042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD71"/>
    <dbReference type="OrthoDB" id="9739313at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="14409" checksum="6E3B1AF748B64FF0" modified="2020-06-17" version="1">MPQQSKSNKPTAGKTSRSAIADVVAREYTIHLHKHVHGASFKKRAPRAITTIRIFARKAMGTKDVRLDPQLNKKVWESGVKGVPYRIRVRISRKRNDEEGAKEKLYSYVQAVNVKNPKGLQTVMVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDB8</accession>
    <name>A0A6A6PDB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_4784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDB8"/>
    <dbReference type="OrthoDB" id="4147798at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="19098" checksum="8A50199D117B06DA" modified="2020-06-17" version="1">MGNRHNRRRTRSRPRNRNRPQSNHARGYQHGCTAPLPAVTAGLPFSHAVGSSVAAGGGGGNIATAFAPAPPPGLCSARFSPTPSLSSQSSFASASSSLNQFPAHRSPVNHWHHQYAAWQERAALQRREQADCDERRRKENLVRVFGGEADDEVSLCEPMLKVVMALFDDIDYVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDF8</accession>
    <name>A0A6A6PDF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_5288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDF8"/>
    <dbReference type="OrthoDB" id="1932925at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF55">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="541" mass="59647" checksum="D4C446FF02CB3F17" modified="2020-06-17" version="1">MAPNFEEKSGAQEAAVTTPSSHTEADVENGSSTASIDKDIAYVFAGTHAHAIDPVVEKRVLRKIDWFLIPAMIVGMWLSVGNDGSARTNVERCDTQAILGSAVLFGMTTDLELAVVVDPTTTPPTVSTDRLSWATSIFYFGMLAGLYPMTFALQRFNIGRVLGPLVVFWGGICMMTAAVTSWQGLYAQRFFLGFIESVIPTGFMCIVSGYYTQGEQALRHGLWFSGTAIFVIIGSSLNYGFGQITGGDLKRWQYIYLLAGSCTVLFGIWCFAVPNSPAQAWFLTSQERLVAVERLRKGQTGVRCQKLKLDQIKEAALDSKVWLIAIVYCSAYTINGAVSGFGPLIVNTFGWTVLESILIQYPVGGLALIFMLLCGWIAMRYRNTRLIQLMLCCLPLMAGCAMIWKSEWTHRAPTPVAGYALLGFYGPIASLAVAIGMENTAGATKKSVMAATIFVAYCVGNIIGPQMVRSESVSDHYPELWLGIICCYIITILASVALYYVMWAENRRRDRAMPVIDEEERDKLAFSDLTDKQNPYFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDG7</accession>
    <name>A0A6A6PDG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pathway-specific nitrogen regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDG7"/>
    <dbReference type="OrthoDB" id="5369448at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="73611" checksum="C7E747E3D394C3EB" modified="2020-06-17" version="1">MPSFTIYEDSTAGLPPISPSSPLSVASDTCCALPDPDEPIASIEHGGPPTSASPSRRVSAALTSCASIISSMPASLVGGGGGGGGGGCDENNDRGDNTNSSPFTPMKERLLFRSPGSVRALQMASPPPFEPRYNSVASPPNSHGKRYKLTAPPPAPPGPSRNGTPRSVQSQSVITNGSGAKMHGSPRQACLTSGRDHEKLPLVLLHATLLPLVCPWSPENMEEILPKHVLDKFKLLAEKMTDNVMARGILIRHPKEEYDVLEERLLESLELKTPRILKCGHWYGEEDEDPIDSAYGDSESGRHEYHDYDEDNSDSECGTPCGDCGKPFKVDSWGVEGRKRWDIKIYAANGLMRAGAWSAAWSEMERVDVEIAPWIPDDLRRKLDEKTQAEEAEARKMADERESRRLEEERQAREQREMEAARRLGEERRARERREAEEAERRAQASVERSPSAEPQVDPLLRNSHGSSEGPEHIIEGLDRTLPRVGRNGGEIPLGTLVQNYLYLLSQDRRNVAIFALSLLVLVLAMISGAPSVTSPVYDGSVSPDLLDDLDIQCAAAPHSTAVYTTTTTVVTTAVPSALASDAESAATMAASSKLPLMQGYRAESPADMHDALASSSAIPESFPNGAHDVSGQTDVDKRTREGPEPELEPEAERDAADAGEVSLPEKPVTASAVAHESSGGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDL9</accession>
    <name>A0A6A6PDL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_6534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDL9"/>
    <dbReference type="OrthoDB" id="5412996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="50"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="447" mass="51121" checksum="56DE5B0CCA40DFF2" modified="2020-06-17" version="1">MDVDSLNRTANRRRAEEWAKTLTRAAIRKLASSFNDNKNCTLGHQLEGSYNLSFPVHFGDGKRWLIRFPVPGKVMCLEEKLRSEIATMKLVKERTNLKVPAIIGWGFSGGSHPTGSAFILMEYLDGQPLGFWKIAELSDEKRSYLLHQLADIMLSLSDLRFDRIGSLTLDDENRPVLKNRPLSLAQDGLIQDGVNISKIMPANRTFSSADKYAECLSRIIRARLEQQRNSIYDVEDGEQKACARYLFESIINTGLQGHRGGPFVLIHGDFRRPNILINPNTFDITGVVDWEWARIVPVQLALPPFWLTDLDVKGLAESDTGPYFAQCRMFIDCLRQHEVARPNDERRVLLSETMENMIAEQSRFWIAMCLVYPYDFDTIYWEQIDPKRRPAEQTEEEQVAQCLHGFHAEEIGRLVQRKMCDLEDYRRQFYSCCTRTSGGGTPGTSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDT1</accession>
    <name>A0A6A6PDT1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_277288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDT1"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF79">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="644" mass="71306" checksum="13AFE3B7E58C0BF1" modified="2020-06-17" version="1">MPPPPINTGAPPHGGYPPGGVYGQPPPPAHQGPPGYPPQGGYGGYGPPQPPQPPQQTQQVYRPGGPVAEVEGAGRSKAQLIVGIDFGTTFSGVAYAFATNNEAKEDIITEWPGAGNQTKQKIPTVLYYDQYQKVVGWGPDIADALAPTGYPKPGVQKVEWFKLQLMLSGNTYIDPINLPPLPPGKSEIDVAADYLFHLRQAMRNQLQKTLGEVFNREERNIRYFLTVPAIWNDAGKAATRAAAIQAGFLRDENDNRLTLITEPEAAAMFCSKTGLLNLKMHDAVLIVDCGGGTVDLIAYEVEEEQPFSVAECTAGSGDSCGSTALNRNFSNILRAKIRKMKLPDGSKTAGKVYAKCIMDFENRIKADFRNNGQKWAVDVGIEAEFPEAGIEEGYMTFTNEEILQCFEPVVNRILELVRNQIIAIQAQNRTLQNVLVVGGFGASEYLFQQIKLHVPPQFQSKVVRPMDSVAAIVKGAVTAGITERLVTHRVARRHYLMATLQPFKEGHHPEQYRVPSLDGKDRCKYTRQIFVQKGQRVKIGEPVKVSFFRQVAPGATLMYEDILYACDDDVCPEYTKDPRIKEVVTLTSDLSRKNLEKDFERMDTPQGTFYRVYFDIYLTLDGSEFNAELVCQGEVMGRCSARFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE44</accession>
    <name>A0A6A6PE44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE44"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="78" mass="8236" checksum="3914EE57CCB1513C" modified="2020-06-17" version="1">MPANVRATVKIPGAAIFYTASSPPARKTWRMKLSPAPCGYACVAPPPPPSKKTGEGTLDQVARRSWIPGASRVAMRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE52</accession>
    <name>A0A6A6PE52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_360099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE52"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="845" mass="91104" checksum="667DADBD3A3E5C40" modified="2020-06-17" version="1">MTASSSLEDSQYELISEGSSDDDAHTASLTESVASESGMDTPDDLSIIDTQDGDEVQLQLPQPLGGHTSDNEQAIEDSESDEDGAGIHDSAPTSRCEHGPFSAHGRSSFLSTLDFPPFPLGDTAGQEIRAVRTLATFSVHDGLPAALRCYNVPPTHNQVALTMRQTMASKQLKLNWRKVYHILFEEETSEEVNVGGLRPIKMKIRQTTGLSPEGKYIPYRDPYYDSPSCPTPDLAVFYTDAFDGAEVPAWFSVLRKLMADELVPCLDISSSPLYGQSPLYGPDGRRVDPTSAVATREMRLCVEARAASTSSMDEDATPQQSTVHHQPDSSPLILDVLPVPLSYLQDTHPDALNRHLTSLMHPHSSVSAKSDEDGSIANESRGWREHWVAIKARRTLNWLFGTAHFLLLALVDSTSAWLRVASRLVDSAWGDHMAPMVRSMEKRVEITANYVRRKKLLLQGVQLALGMILGTFTILVVHLAFMGVTSQLGGVLRISRQDAVVATPTPAAQVASSAVGAPLMTPCEWHACGYAFPGVKVKGWPQGCGEGAGAKVEETRPKGQEKDLGRSLQEWAHKELASYTAAWTGWEEDVVAEAAAPVMKKLDAWSADKKDGVALSSGTGAKNTNNDVVKDASAPKAKAADAASSSSQQQKQKLSKEHQKQQQQLATTPTTALGYLQHLMFPNAAGIGAPQVRDSIALAHRNARALRARVQSEVVRTWETGLMLVDRVRQGELAAAAAASGAAAKAKAKAQREGAVGAAGRASKALGSFFGVDEWRASAAREAGAVRKGWEEGLSQARRRVEEVWREVPVERPSWGRAKRNAVNLQLDGCGGGCGGGYETYAGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED2</accession>
    <name>A0A6A6PED2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_360300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED2"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000015">
        <property type="entry name" value="Proteasome subunit alpha type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="26770" checksum="F3D1AFDF508DBCE9" modified="2020-06-17" version="1">MFIARSEYDRGINTFSPEGRLFQVEYSLEAIKLGSTAIGVATGDGVVLGVEKRVTSTLLETSSVEKIVEIDRHIGCAMSGLQADARSMIEHARVESQNHAFHYNEPLRVESCTQAICDLALRFGEGADGEESVMSRPFGVALLIAGYDEDGPSLYHAEPSGTFYRYDAKAIGSGSEGAQAELQNEFHRSLTLSEAEILVLKTLKQVMEEKLDAKNVQLASVTADRGFRIYTDEEMAEVVGRLPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEJ4</accession>
    <name>A0A6A6PEJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Trafficking protein particle complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_331414</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10256906at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055505">
        <property type="entry name" value="DUF7077"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056916">
        <property type="entry name" value="NTS_TR130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022233">
        <property type="entry name" value="TRAPPC10/Trs130_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056913">
        <property type="entry name" value="TRAPPC10/Trs130_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23274">
        <property type="entry name" value="DUF7077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24967">
        <property type="entry name" value="NTS_TR130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12584">
        <property type="entry name" value="TRAPPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23036">
        <property type="entry name" value="TRAPPC10_1st"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24965">
        <property type="entry name" value="TRS130_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="6">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="6">
        <location>
            <begin position="267"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="6">
        <location>
            <begin position="412"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Trs130 NTS" evidence="8">
        <location>
            <begin position="782"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7077" evidence="7">
        <location>
            <begin position="1121"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 C-terminal" evidence="5">
        <location>
            <begin position="1486"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="172"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="584"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="726"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1009"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1075"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1601"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="750"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1094"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1690" mass="183730" checksum="7E7637D428279E96" modified="2020-06-17" version="1">MDGQSTSKVTVEYHDPSGVYPVLAPLLSSRLPLRNLHWKSPTRPLRSIDSLHVELLPSGAHLSSSLKRTASGSAVPGSTSVESRQEPRRHQIPGLRRTPYLKVFLLRCDDSESYKSTARKQVREWVRAHTASASQASSSSSSLPAGSKAGQENHDAFEWLVLHVVFPDTPAAAQPRWSGSGSGKGGDAGGVERPSSGPKWPGKSSSTILEKLRADFNVSSKSAPDRVAQVRIPKSVLTGEAPAQAQAQGQQQGGGLRPPSTANEDLHEQEASWNDVVAKLKTLILQSFDLRVRQYEEDIREKDAQRALPGWNFCTFFMLKEGLARGFESVGLVEDALIGYDELAIGLDSVIRDLAMGSASGQATSFLEHTEDLQQLFRKLREEGTDISIEEGRNDGPYTTGSSDLAPFDEDLINPSRKNYRDLIMANNISIFDFRCYIFARQLQLLLRLGNPRSASKSQLMAKLSEPSPSNLRARGSVDDLKIGTKAQQQHQHPSDEAEDLLSLAELCRRATSFVTSTSRVLKEDLACGFSAPSDDASLDSSDITLIASIASSWLFSVSQQVLEATSTPSLPISSFAAHPSTSSSAKLLSAHKSSRGHEPKSGPSPGSAANQPEPKTMLHPARSSSLSHRRSSGSGGFDPPYAVTPPSGQIIYEQPRPGSTPPAGPISPPGAVGGGARTGLDELAAHRAELLLLQRRVIKETGGKAGWWIGWDAVVRMGGGVVGDGEFEEIDLGRSGEESEREEEDEDKGADKEGKEQSRVHEGTETTLEGKAWAKGLCNTRLRAAAASTNDFRAQYAQLSELVVKHFAAAGRSRAEEAVLADLAAVKFEMGDYAGAAMYFSRAVPAYAEKRWTRVEVAMLKLHAQCLKKLHRRDEYVRVMLHLLSKSAARAKAERKARWWGRGSIAKDEDAAAEKEKGPEDDDISRWLDDGHITTAGYLTELVECSAGLPYDMMVPMSQYFADTTVDPHIRHVPGRDGFRLLLRFTHLLEDDLLVNKVKLRLARMDGAAPSAGGNSSQQPQPGREIWLDGPDAPLNVRRGSVRVWLDSNVSTVGQFYVDKIVLEAGKIVFVHEPHPRPSDPASAAGSMSQQLSASSNAPAADPAGPRVPRSARVWCFPNPDALAVKVALSRFIHIDRPRSLDVEVKTGHNDVGKLELRLRAASAGLRLRTANVEMVSVTREGNEKEENVVDGVEMGDRGKPGIIEVLSLPAGCTARLKVPYELETSLRDLGVRVEATYNAATKGGAEERAEFVFVAHSVIPVELPLDVNVHDLFKARVLFQRFHIHTAGSLPLEIVRSQLEGTRLYDVQSPPCGTDESMIIFPKQPATLVYRIEKRDVSSGGGKVGKEEADQPLQLTVDYRCVDETVLTGVEALFSSAVEQAPAARPLTHLLVPVFRERFKAWIKPTAYEQIALLERVKLPSFAEMAWADVLESVPADMRQLPLAFLEKWHKDHPVVTFSPDIAPRKRRRPAPPPPDPRRIVITVAVPHVHVVHTASLELHLSSPQPSPTSAQPRIIPVAVGVPATLRIKYTRRWGSLLATQQRADGALPFVFDVLAQPDLWLVGGSRRATFEAKEGEEVAFELLLVPLRPGPALLPGVEVRAAPRRRPAPAPPPKGDGGGGMSSGAQAEEEDEAIACETEYKSQGMTVLVVPDVRSTSVVMLGRERAADSGGVVLVGDERRGKVEGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEN4</accession>
    <name>A0A6A6PEN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_10774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEN4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="22048" checksum="73CFB3D8E19CDBCE" modified="2020-06-17" version="1">MPRKRVRLGRCTRSQRFGISIFFVGSVRMGTVRTCYVRSVIYPRIGRGIKGMRIFSDERCRNECNRFYLTYSEFSLSPSPSPWELRLPRAVSWLTEMVHRPAKPPRQTEDRPIERRKLQPRRAPPQPRPSSVLPSFFLHRYPNYITVSRPGRAMSLFNLALLAFHLSSRCVIPNLITSSRLMTKVPALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFM0</accession>
    <name>A0A6A6PFM0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_277135</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Associates with the nuclear pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFM0"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17963">
        <property type="entry name" value="DEADc_DDX19_DDX25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000849">
        <property type="entry name" value="ATP-dependent RNA helicase DBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 17 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="4 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="21">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="114"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="293"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="16">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2462163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="483" mass="53166" checksum="C319451EFE2C8A89" modified="2020-06-17" version="1">MSTDTPAAAPTADAPPADTPAADAPTADGPAAEGGGSVEKSQADGAPEAMGGSGLREPEYDVEVTLSDLQADPNNPLYSVKSFEELNLRPEIIKGLHALNFRRPSKIQERALPLLMRDPPTNMIAQSQSGTGKTAAFVLNMLSRCDMTMPVPQALVLAPSRELARQIVGVVQQMGQFVQGLNVVAAVPDPRQRNQQITGQIVVGTPGTVMDMIRRRQMNARSIKILVVDEADNMLDQQGLGDQCKRVKALLPSQIQLVLFSATFPENVTTYARQFAPRANELRLKHEDLTVEGIHQFYLDVNGEDHKYDDLVKFYGLMTISSSIIFRRDTAREIEERMTAEGHQVAHLSGGLEGSDRDRVIDRFRSGEAKVLITTNVLARGIDVQSVTMVINYDVPEKLNGDPDYETYLHRIGRTGRFGRVGVAITFVHDKSSWSKLMDITKYFNVAEQLVRLDTNDWDMVENALKLVLKNPRAGVATDKMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKQ5</accession>
    <name>A0A6A6NKQ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferritin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_294965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001713">
        <property type="protein sequence ID" value="KAF2452291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKQ5"/>
    <dbReference type="OrthoDB" id="1001765at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025354336" description="Ferritin-like domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="35779" checksum="109351046537E505" modified="2020-06-17" version="1">MLSSTLSIFLFGFSTFLVSAAPLCPETIDMAGGGLPNTTLPSTVSDSGVREIQLAQFLEILKVEFFTARFTNVTDWGKTDYSNNSAEIVGKIAAVEEVRRESLGALFNAYKTATIPPRNYSFPVASTQDFFQLADLIGSAGIGATIGLSEHLALTGPMLARLVASILTVESRHDAFFRYVMGKVLNPAPFDTGSDDIWAYSIALSFIVPGSCPVEVPVPVLPKLNVTQQEQATARYTNSTTGTNSTILQQFSWDPTQMPFVVEEGKQLLVGWVNQVNVPTYTPLGVTSWAKGTSTVPQEMNGVAFAVIATQEYDNVNDLAFGTLAGPVVVPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKY4</accession>
    <name>A0A6A6NKY4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKY4"/>
    <dbReference type="OrthoDB" id="3965769at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11454" checksum="50A83205B899D88F" modified="2020-06-17" version="1">MSSSQTQKQQQPTKPQRGEAEPSHRAWVCCKCGYFNRTGKYNTCSRSTCAEKQLDKLGHTRCAKCRPRGFSDYGILRSSKTNPDFMLLDEEDVPELIFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLH0</accession>
    <name>A0A6A6NLH0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_158851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLH0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="84" mass="9978" checksum="5D2DECACA528FBFB" modified="2020-06-17" version="1">MAWRNFQAAFLFAKRPVLFLNFGFFFGRGRGEKIGGPFFYWFLQTSSFSFFLFFFCFLLAVFVFSWCACTFFPLSFFICLATRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN5</accession>
    <name>A0A6A6NLN5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLN5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="102" mass="11263" checksum="5D0834847C20C527" modified="2020-06-17" version="1">MSGAGRANLEAKRPPATATVSDRFAGLGGSGWCVAAAWWRAGRICGWLAGWLVGERRGCWLSWTVDGTGDMWWWWSVGRLDYDFACELARLRAWVLSCPGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM04</accession>
    <name>A0A6A6NM04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_358291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM04"/>
    <dbReference type="OrthoDB" id="5130013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="497" mass="56534" checksum="5D4AA928A334CF93" modified="2020-06-17" version="1" fragment="single">MASLDLEQLLKSLHLLDRKIFCDRELPICRNCVRANRLCGGYGTRLSWPREHDKRRGVVAYTTVKFPVAPRIGRQFINTSSWDIELHDHLAAAGPILVQGGESILQFKLPLLDKAALQPYALANHREAQLFEYFKSVAFHTLAVVDDADRAGGIRSLLLRMALSENTYGASAVRHSVLALASLHRSGLNTQARQLKYAAVNALRKSAEQGIGTTEGQQHIAAGMILCSFELLLPSDTSFQWPLYVCGSKMVMQGVFSTTPKCEGDLSTLIEWLFYHDVFADFSLRHWNLCDRERLFRCRHKIFAFLRANNDSHDQIMGTLGCSYEMLELVSQIFTQTLRPEEAGYHRDDYNNSLAELETRVINIRQQDAAATIFGRPDPLKKTHAENVAELYRFASLIYLERLSKNFSGLSAKVDAWVDEAFRVVAELDTCERPFPLFIVACEAKTDERRDMVFELLDRTAAENRSRPLDRVKRMLEVLWVQDDLVIGEDLDYAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMB9</accession>
    <name>A0A6A6NMB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_328633</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMB9"/>
    <dbReference type="OrthoDB" id="5392779at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="108"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="743"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="746"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="839" mass="91533" checksum="A36024FE3EB9A996" modified="2020-06-17" version="1">MDAVSDAARESPDSERGAESEAKRRKVRKGTRSCWECKRRKIRCSFSTASDSVCIGCRRRGTSCVTQEYPEETAAAALSTGDRGRSMGDRIVRVEALVEQLVKQVGNRNNGSTARAGSSALSEDGGPNTGIPTPGSSDRAESARFLTAYEPSGPDLGLESSHLEGLFSSPMMRTPDSPPPPTTIAPSRGIRYEQVSATLHAALPPREDIHLMIKAGIDVSLHKLTTHPYPVLAQNPGGGKGDLAEIPEAKTHPALLAKYLLILATCLQFVHPELHAEEIHDLSEPPRLLMRRLADTAISLVTSNDEFLGSVEGLECVMLESIYEANSGNLRRAWFACRRAMVVAQMMGIHRSGIQQPLKVISLSKPVYPSYIWYRIVATDRQLCLMLGLPQGSVDVSMASEAALACDTPSGRFERKQCVIASRILERNEWSDPAIADSFAALQELDAELQRAANEMPSIWWLVPNLASLVHDPEKTFWETLRLLEQMLYFNLLNLLHLPYMLRSSTPDTDQVGNGGANYKYEYSKLTSVNASRELLTRFIMFRSFNRVAFCCRSVDFFALTAAMTLVIAHLDGHRKQRQRQHSAGIGGINVLAHHRNGDRAMMERVLENMEAVAKLSTDVLSERSSSLLRSLLALEADAAEGRHGNVDRDCFAAAADDGQSLRIGIPYFGTIRIDREGVISMDAPRRATPPSPAQQRHMPTETVVSSPAIRASEDGYTAGQASGRLGVDILPPAQPPFDDVASEMPSIPQQPQQVAQASSPAAAQLPRMQAHQPFAPQFPTAIDDALQQEYLYPGLTAVADDWAFQGVDLAFFDSLTRGSGVECAGDGSGSWVNLEGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NME6</accession>
    <name>A0A6A6NME6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_375217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="757"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1179"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1565"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1661"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="627"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="858"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="148"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="325"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="757"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1188"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1575"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1610"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1668"/>
            <end position="1678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1693" mass="180276" checksum="D688C0682006AE4D" modified="2020-06-17" version="1">MADPDTAPPAEPPLAEPESSLPSPPPDPEPAAATTATKSPPPTTTTTTTTGAPAAKKTENIPPRRPGMATGTTGAAKRPSTLGAAKPSSSSASRLAPGTKPAPGSTLASKPPARPPPGTAARRPAAGAASDHDVSATSGEETTRARRAPPSTAAGVGGAASKRSAPGAAGAAAAAKPSAASSATTGAARRSTMGPSAGAGGAAAAAKRPGTTGGAAGPRASVGGASATMATRSARSGTAGSTTGTSRTGAGGTMGPPKKPAPGTAAGGSPSATRMRTRTPSTTAASLHARSPKSPKSSPESARTRALGSRASAAAPSDAEDQRASTPTPTSPTHTRSVSMAEDASSLDALGSSLHERVGGDDIPASVATAEDLLRETHLREELEARVKALDAELGELRAKHAAAEALAAEHASTIEDLRKELSPLRPVHDELEKMRGQLHAEQEASAESAEKAAKAEELADITRKLQEEIDNAERRLDEDERRLKEERQKSVATVKELQEQLAKAKDTEAAADGARAALEARSKELEDRVAELTKASADARDKEQAIAQLKEDMDKLEARLADKEETERRAVDLEARLKEFEVKVDRLGELEGEAKDKDDMIGRLQLDIEQLHQRATDAARTHDDASAAAGKTIDELKAEIEAARAAHGDELKSAKDAAAQSDQTVVEVRDKLAALERAKGDEVAARDKDVAEARAAVEALQGQVQALQLSGADSGKVVEGLQAQLREVEQLRESEAGAKAAEAAELRALADELRAEAERVREQESAKAGEKDKEVQGLQDALAALQTQVQEAQQSARDAAAAKDEELKSQAAVVEQLQDDLAKARAAAADDQSGAAAEVQELRAKLAALEEGGATRNAELEKAKADAEQEVVSLKEVIDSLQTDMKSALTAKSDAAKLQADEAVGLRKAVERLQEENAGLKQKVAEREGAVKELGESGVQDKERAARLEKEVADADARLEKLRAEEAGKYQDAVEKLQDEIRELRQAAANHEDAVARFHAESEQSAAELKKIHAAELEAARGDATQAHDLEAARAAAEAEQARLREAVAKLEASTKDMQATIDEHEDAMALLQRDADAEKARLEERVRELDEVNAHHERLQQVRKEEMDRASEELRSLQNEIESLRITSEDDSGAKEEEIRRLNGVIETLESRAKMAFEERTKGVVEKEEEIDRLREQLEKSGAGATEEHAKALKEKDEEMERLRALLEEARLAAEESVRKDEEIERLEKVVVDAEAKAKEDVATLTEAKDAELLSLKDEIKALSAAKESEVERLSERVARLEGELKEAAAAKEAELKDLQLRYSALEESVEAASDALERAHKSLSATTHEKEALESALDMFKREAEDGTAHHAAELAKLNAELSRARADLAAADEKHLAELKSVGDDYARENEALRANLSEEQRRELDAVTAKLDQAVKERGAKQTELDDTLARLAKEADAAAAEHDKQLGETRAQLEALTAERGAHGQALEQARAAAQAAEAQLAELRTRAAEAEAAAKDERAALRRAVEDERARADKAEMSAGVAAALREEMEGAERRVAELEAALKDAREETERVRAAVLRGGGAGGVGGEEREGSGASEGERGEGAARGGEGEMVQGQVGLLEQHQHDNTRQLEHHELHGDAEASRRERERRLRQELAIEGRIARMKEEAKQLEELNNELQEESKRAMKRLSEMSPISPTSPRVEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMK7</accession>
    <name>A0A6A6NMK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_293796</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMK7"/>
    <dbReference type="OrthoDB" id="3053196at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="12">
        <location>
            <begin position="135"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2452962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="426" mass="49131" checksum="5F7E040A7E230A43" modified="2020-06-17" version="1">MSSATLTLPPCLNPQAQQPRPRGAKRRKAKSLARRCKAFMMRHTWVLPLAVCCVVAGAYLLNPTPSNPVHQALFLSYPLPRDADAPADAPTMYGKGAKDFYFVAYYVAFLTFTREFLMQRMLRPLAVRCGIRKGGKQTRFVEQVYTAIYFAVFGPFGMYVMSQTPVWYFNTRAMYENFPHREHDGLFKTYYLLQASYWAQQAIVLLLQQEKPRKDYKELVGHHIITLALIWLSYRFHFASMGLAVYITHDISDFFLATSKTLNYLDSPLIGPYYAFFVVVWTYLRHYINLRILWSILTEFNTVGPYELNWDTQQYKCWISQIITFGLLASLQAINLFWLFLILRIGYRFVTANVAVDERSDAEDDDEEQEEHRHQHQQRKEDGAADGLLKQHQPDILVNGEPVEAGGKEAAATGVQTRSKVRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMV0</accession>
    <name>A0A6A6NMV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cenp-O kinetochore centromere component-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_382747</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-O/MCM21 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMV0"/>
    <dbReference type="OrthoDB" id="10050372at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031511">
        <property type="term" value="C:Mis6-Sim4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018464">
        <property type="entry name" value="CENP-O"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14582:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14582">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT MAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09496">
        <property type="entry name" value="CENP-O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="228"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="350" mass="37743" checksum="DB430DC6EAE53021" modified="2020-06-17" version="1">MAAAADQSRADGLDAEIARVRAQAESLRARRSLLASTVLSSPRTLARLRNAEKTSPSPEPKLTSAIKRASEHAKLHQENLHRICAGITAFRVQDPDPHAVDGGRVLGVRIEAFSDGHFLPPYYLLLHKPHPHLHSLRLHKHTIPPCIPLPALLSKHLPQPPPRRRRRRHDTARGTSPTGPDDGDADGDDADALPPPRQDLPALARALRRELCAHHLRIAAVARARRAAGLPPERTRVPGSAAEAEVRKGEEVADADEDAGRMRPVGKLDIVDVSAAHASAREVRIGWADGTEARVRVSREGKAVGAVALGPEADGDGEGRAERRRDIERAVLGGNGLVAEVVERLEGVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMY3</accession>
    <name>A0A6A6NMY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_293599</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMY3"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="37"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2453036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="380" mass="43201" checksum="32D28CC132D58694" modified="2020-06-17" version="1" fragment="single">GFEKLSARVQVEEERVPDYKLARFYPVRLGEVFKSRYQVVAKLGFSTASTIWLCRDLEANNLLTLKVCITGKSAPKVDNEVAISRYLRSIDAEHPGKDLLRLALDDFQITGSHGVHQCLLFTPLGLSYTDFRNLFPEKWLNKELLQQTLLLVLLGLDFLHQADVVHTDISPNNILLGAPDSSVFSIIEQDELEHPSARKILPDRTIYCSCPMPITSGPPVICNFGAAKMGGKHTGDVMPGVYRAPEIIMGMEWDSKIDIWSVGVMIWDLFEGGRLFRAVKDGHLNDEQHLAEMVSLMGHPPRSFLERSETSRRYWDAEGNWIASTPIPDQTLEMREKRLKGKDQELLLTLVRKILRWHPEERPSAEDLFEDEFLTQSLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN66</accession>
    <name>A0A6A6NN66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="3 15">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 15">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_310892</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="3 15"/>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN66"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000033">
        <property type="entry name" value="Histone-lysine N-methyltransferase, H3 lysine-79 specific"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021162">
        <property type="entry name" value="Dot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF0">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017570">
        <property type="entry name" value="Histone_H3-K79_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 15 19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 15 16" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="10 15" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 15 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="18">
        <location>
            <begin position="62"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="274"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR017570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017570-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2453151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="381" mass="42555" checksum="309EA4F89D5089F5" modified="2020-06-17" version="1">MVRDVTVFPGGAEEGGGKKKRRGIIHAADFTGGDDKASYVPAFEEEETILVELQYPSVTKPERFELVVPKKDDGFKPLEDIIQSTEHILRNYLPPSQKEALLDDSTGIVRRLKRAIFHRSAPNFRTVLAEFNEIISRAVRDGTVARTLDSTTALPLPLVNRILEQCYARTVSPRVESLTEYNAGSDNVFGELMPRFAHQIFADTGLKAEHVFVDLGSGVANVVLQAALQTGCEAVGIEVMPNPARLAERQLREFEPRCRRWGLKTGRVRLFEGDFLNCPELDAILQKADVVLVNNYVFSPATNEKLVIKFLDLKDGARVVSLKNFQKVGHRITVRNQEDPVNLLEVERKEYGSGCVSWVDRGGEYFVAVKDSGRVGRMLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP09</accession>
    <name>A0A6A6NP09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_403598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP09"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="254" mass="27049" checksum="BD089D50D877FC82" modified="2020-06-17" version="1">MPPAPGPRLPAAAAPLEALPTAAEPYALMGPPLPIASASVTLREHTTAGPLPARRATNCAARPPHRRWPVLESLRPGDSLLSHAVPASVPGVTEGYLTHSFDLVSGKVATLLAFVAVVAVFARCRRRRQVRATGVNPAPPNPAGAKLLVEPPQSVVPLPPWTSPPKPLPGPHNHPFFAEVASLPAPTLRRHSQPAGMDASNPTTAREIETRTRTFERRVSANDALVLHRQVQDTRIGGNTGWRRSSWVLAGKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP30</accession>
    <name>A0A6A6NP30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_293030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP30"/>
    <dbReference type="OrthoDB" id="5355526at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="74" mass="8040" checksum="EFDC5C3A21BE65CF" modified="2020-06-17" version="1">MCYQVVERYAACRCLYYKHGIDRCAGYGQAGHVVQEKTVLVGYACSMHSSHRAETASMSGHGILPDSGYSSGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPB4</accession>
    <name>A0A6A6NPB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_388014</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPB4"/>
    <dbReference type="OrthoDB" id="88at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000173">
        <property type="entry name" value="Mitochondrial 54S ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="15627" checksum="8BB04255FC01DA41" modified="2020-06-17" version="1">MPVSAIRTITKNQNGVGAFILQCKRIDFHYCDWEGSSKGMRSFLRSRLADFARANPAIEINVSPRPRKQPILRGVYVNGRDKQICVRNMEPTQIIKKCELLRDASGEPLRRDTKPVKSINESVRGVWSPYHGAQFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPZ1</accession>
    <name>A0A6A6NPZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPZ1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="11809" checksum="5CF30AB36E6F0C46" modified="2020-06-17" version="1">MPSSSKNRQVAKVDPAAQQVRQIETQEQHASANASAGLNLNLFAAVSGVFSGRSKKSQQLKDDGSYYAEEEQQSAARAQGVGAGSLAAAGQARADSGARRLKQTDHLGIEPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPZ8</accession>
    <name>A0A6A6NPZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPZ8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="221" mass="25022" checksum="915BCED3BAFE9213" modified="2020-06-17" version="1">MTRRLQQRPVEYPLKQPNHKHSNDALGGRTEPAICGVIDEHDSPNLLWKNIPLFDNLKEHLDDAPKYYPVKIQLREPSALQCPKTKKLPPTLLSSAAPACKPYFKYDGRPTFPLNKLLEITKNAGTDRAGVMSYNIGSISLNCIFVGLGTSCTNFMDPHGFDTYVGHGPRYPRRDTDHIDDHEHPDDIDLREVHSNDLEVANAVEDDRAWSKEWLALLEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR70</accession>
    <name>A0A6A6NR70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_353401</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR70"/>
    <dbReference type="OrthoDB" id="5594999at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="209"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="858"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1175" mass="128185" checksum="982FF4B2BF1FAFCA" modified="2020-06-17" version="1">MPQSLRHESLLVPVTAVTTWGTKILAGEGPFLQVYDTATYPAKHLNAIRVFESQAIHGIRLRHEDDVDPEAVIWGGSCLCIVSLSTVGLTIECRKTANVQVNDWILDLCLMSGDKMNESRAMQDIIGVLVTAHNALFALCAHSNDSSRGFYDLAELSRGTRCILYSAHLQLLPEGRILVAAGTAFGEVLVWSLTFHLWDGQRAELHYIFSGHEGSIFGVQISEALEHTSTEVPWRKVLASCSDDRTIRLWDISGAVDRASSAEAKSLEQALAERESGFGIGWKDDVHKDGCLAMAWGHISRIWGVRFLRLGEDDEQGKFPYHLVSFGEDSTCQLWNIRPREGRDGDIESPLLLEHFGEASYHSGKNIWCIDVVGTGRHSMILTGAADGSVVSFSPDSHACGKASSCEMEISNMKVMPTAKEKASDPPAAERQNQNNYRQPREDPFRCYAFTSERTFVVTTKSGKVCRCDTGVHTSPSGKTSITLDVTDLHYSSNDLRGYSIAAGATNMGLAFLTGSTGVVHCYDSHTNTISDILDLEGKPAGLFVTQETSCVAPQSCVLVATRLGLPVAQQQLLQRAGESPCLRVNSAFLALPESFMVTSSVSIWRNPDFVTFLGGRNGAILFFASIAFPASQGISTYQQPVQPSQYIPHIHGREAVTDLKWLPVSTALSSDRQGWLVSVGRDGTCSVLQFTGLDKPPTLVHKLGLPFGPNVEGICIQKHGAQEHLMFFGFGGKRFVVYDDSLKQEYTNVECGGAHRNWAFISTGEGDETDGNCRGMFVWTKASKANVAYFPKFSHQIVKSGSHGRDIKAVAISPTRKPGSQNYLIATGAEDTTIRILEYELSGVLDVSGQFRCVQVIRKHTTGIQQLAWSNDGYYLFSSGGNEEFYIWRVHSVPLLGVGIVCEGVCPPKSEARDLRVTSFAVTEKSRLTNFADSEERTFLITLTYSDSIVVVWQYSTSSNSSWALLCSGSYGTACLLQAAYLPSSRTPPLLTAATDGYLALWYPPQESLVTELPRIQASAKWRVHQNAIQCLDCCPIVGSINLVICGGDDNALSLTLMRSESNPSASTLLIPDAHAAALTACTVTTLSRDEGSHHTRYSLVATTAGNDQRVNIWVVRVDLAIPGVEGITVLRLATRATSVADVSDMSQFTLSRGEKSIAKLIICGVGMDMWTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRF7</accession>
    <name>A0A6A6NRF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WD repeat-containing protein JIP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">WD repeat-containing protein jip5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_291679</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRF7"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="364"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="424" mass="45445" checksum="1401CAD873965361" modified="2020-06-17" version="1">MFDTICNLPLSSEVFTQAIHPRYPLLSVGLSTGHVETFRLPNIASDPDECESETARPSAGSSSGFGRIETAWRTRRHKGSCRSLVFSSDGDIVFSAGTDGLVKAAKAETGVVEAKIAIPKDLPRTANEDDFPSLVHALTPQTLLLATDSGALHIYDLRDSDASSSTTYISSKPQQTHHPHEDFVTSITPLPPSAVSTSRQPKQWLSTGGTTLAITDIRRGVLVQSESQDTELLTSAFVGGFAHKGTSVGEKAVVGSAGTLSLWERGVWDDLDERIILDRDGAGVEALVNVPDHLEVGRGGKILVAGLDNGVIKGIQLGINKVAAEMRHHEIDGVVALGFDVAGRMISAGGETIKVWHENIDDDQESLHHESGDQAKKAASSDGDSEESSDSNDLNSRRKRTRWSRGTSKSRARNTGVMHIKGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRX0</accession>
    <name>A0A6A6NRX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_291210</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRX0"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000005">
        <property type="entry name" value="histone deacetylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019154">
        <property type="entry name" value="Arb2-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09757">
        <property type="entry name" value="Arb2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="12">
        <location>
            <begin position="77"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Arb2-like" evidence="13">
        <location>
            <begin position="439"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="720"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="805"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="732"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="818"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="860"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="871" mass="96033" checksum="647D9455CC543674" modified="2020-06-17" version="1">MPDDVPSSEVESSESSVDLVDETEEEALSRRYVVEVVVPKPRAPQALPYSSSRSGLVYDPLMRFHSEPGNRSDDDIHPEDPRRIHEIYSELRNAGLVDDASQQYVPIDMQLWRIDARHAKLSELNLVHTKDHIKWVKSLENKTNDELNDLSNSLDSVYLHQLTYDCARLSAGGAIEACRAVVAGQIKNTIAVIRPPGHHAEHCRPGGFCFFNNVCIAARVCQQDFPQKCRKILILDWDVHHGNGVQEAFYSDPNVLYISIHVHKNGTFYPPGNYGDHKHCGEGQGLGFNINIPWTKHGMGDGDYLLAFQQIVMPIATEFDPELVIVSAGFDAAEGDMLGGCFVTPACYAHMTHMLMSLAGGKIAVCLEGGYNLRSIARSALAVTRTLMGEPPERLPSVEPSPSAVNVVQMVMRQQSRFWRCMYPKDLAAGLKERTGGERMHDIVRAWQSKVLYDEYGMSPLFILRERISKSYENQVLATPNFSEARPLLVIFHDPPDVMGVPDPRTNKLELHNTWLTDVAKIYVDWAVKRGFGVVDVNIPKHVTNSDDDGAYVGSEGPENNPMEAREVANYLWENYIELSDATHIFLMGIGAAYSSIIDLLSTIEGCTETITHVFAFVANNPLQAVRRLADDSISSWYWSHSSVFIAHDHAAMDPERQRKPRRKYGHLIQSPDTEIPQMLATHHPAVCETLEEESNGWQEMAEQMARQAKAAAEPVVLSSQSSAFPLPGRSSALTSPTTTTFKREVTDELAGPGPASNSAPKARTPPQVSSAMARNRASAPMAAPLASTQHLRYQQQMQYESPLDQIDGASDPRPRTMPAAAAASMAPSVARELNKSPGRPPMGWFTHGPSPEKVKGAGPSPGTGSPGGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSD0</accession>
    <name>A0A6A6NSD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-I complex subunit VPS28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_352533</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSD0"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.200:FF:000003">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="9">
        <location>
            <begin position="21"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="8">
        <location>
            <begin position="144"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="27007" checksum="07EC602F05BCD7DF" modified="2020-06-17" version="1">MYPQRQLPYAPTPYSYTPTSALSSTISLDEEVKLFSNNAERDLYESLAEIYSIIMTLEALEKAYLRDSVTETEYTETCNRLLKQYKSNLKNEAVAQAFVDLETFKREWDMECPRATERLRVGIPATDETPSAPRPRQNASGGGPAAPTVASAIETFITTLDAIKLGLREKDMLHPLLVDLIQSVNKVTDVDFDGKPKIVQWLITLNQMRAAEPLTEDQVREFQFDMEQAYYGFKSTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSQ1</accession>
    <name>A0A6A6NSQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hexose transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_374061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSQ1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="48"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="59592" checksum="89F5E1ACF8962487" modified="2020-06-17" version="1">MAPKIGWRGPKTTSRIHGEDRDVLEDQAPQLERVNWMRDPGLRRLYAWAFVLWIASWTTGYDGSMLNNMRIIPKWEDYFDSPTGGLLGILTALYQIGSLASLPIIPFFADHFGRKFSIAVGCVIMIIGGVIQGAAQNLGMFMGGRFLVGFGNSLAQLCSPLLLTELCHPQHRGRVTAVYNCLWNLGYIINTWLTFGTQHINGHASWRIPAFVQCAPAVVQVIFIFWCPESPRWLIAKDRDDKALHILAKYHANGNAEHPTVQFEYREIKETLAMEFQSKKTSSYLDFLRTSGNRYRLMLICSVGLFSQWSGNTLVSYFSTEIYDSIGLTDPTSKLGINGGLAIMSLFVSVLCAILVDRVGRRPLFLSATGGMCFAFTIWTICAAQYEQKRDTAAGKAVIAFIWIHSFSYALAWSGLLIAYSVEVLPFKIRAKGLMIMNLSVQVALTVNQQLNPIALDNLPHSYDLFIIYNVWVFLELCFVYFFYVETKGPTLEELAKIIDGDEAEVAHVNVKDTAEPVYHEKAPETKTSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT23</accession>
    <name>A0A6A6NT23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_387327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT23"/>
    <dbReference type="OrthoDB" id="10256055at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41677:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41677">
        <property type="entry name" value="YALI0B19030P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="42768" checksum="8A3371B8B686F03A" modified="2020-06-17" version="1">MTQAPAATPKANWKPIIQATPSKATGPSGSSNFDPSKHITYKEPSQIIKMKDLGFPEDAGVSPVAVCQPFQLFSPEAIGQMRDEIFQPVVMDKCKYSSNIAACQLRGYSPKYAPFIYDAWNNSETLSIISKIAGVDLVPVMDFELGHINVSVKSEEQTKEELAVISNEKRFYADDEGIAGCPWEDDKPIVGWHTDSYPFVCVLMLSDCTNMVGGETALLANDGNVLKVRGPQMGCAVVLQGRYITHQALRALGAQERITMVTSFRPKSPHIRDDTVLTTVRPISDLSELYYGFGEYRMEILEERIREQLRQLRDRRRSGKKMNTTAFKKFLAEQEAFLKHMNNEMVEEDKVQVGYMDEIQIPDVVVGGKSSSERPAKRARVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT46</accession>
    <name>A0A6A6NT46_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gylcosyl hydrolase 115 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_290855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT46"/>
    <dbReference type="OrthoDB" id="4849794at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.520">
        <property type="entry name" value="Glycosyl hydrolase family 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031924">
        <property type="entry name" value="GH115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041437">
        <property type="entry name" value="GH115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042301">
        <property type="entry name" value="GH115_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842:SF2">
        <property type="entry name" value="GYLCOSYL HYDROLASE 115 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17829">
        <property type="entry name" value="GH115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15979">
        <property type="entry name" value="Glyco_hydro_115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025436459" description="Gylcosyl hydrolase 115 C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="domain" description="Gylcosyl hydrolase 115 C-terminal" evidence="3">
        <location>
            <begin position="833"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1020" mass="111451" checksum="69A2FF3983370C80" modified="2020-06-17" version="1">MQLARSLLSVAAPLFAASAAALGQERIVAFEPPAAGGYALTDGSQPVQIVVDQGDWPGVQRAAGDLAADFGRVTGLNGSVLYASGGSDAAAAAAAGVVGADLLRNGSASVGSAAADPGVIIVGTLGKSALVDAMAQAGLVDASEIEGEWESFVTQIVYSSDPDAGSALVVAGSDKRGTIYGLYDISEQIGVSPWYFMADVPAQSHDAVYVTKSKVQGPPSVKYRGFFINDESPSLTGWINANYPEGEYGPGFNFDFYKHVFELLLRLRANYLWPAMWNSMFNVDDPRNQPMADSYGIVMGTSHTEPMMRATKEWSVLGEGEWAWDANSDGLRPFFFEGAERAKGYESLFTVGMRGVHDTAMSDDVQTGLLETVVDAQRDILADVYEVDDSSAIPQMWCLYKEVQAYYEQGMRVPDDVTLLWADDNWGSVRRLPTGDEIDRPGGAGVYYHFDYVGDPRDYKWINTVQLQKTWEQMHLTYERNARQIWIVNVGDIKPKEIPITHFFDIAYDFTRWSHDSVPEWTAEWASLTFGSDYAEDIADVVNRYGKLAIKRKYELVDSTTYSIINYEEAESLLAEWKSLSEKAQGIYDQLTDAWKPAFFETILHPVLAGATVYDIHISSAKNNLYASQGRNSANMWADYVLELFDRDHDLTVQYHTLLNSKWEHMMDQTHLGYEYWQQPMRQQTPALKYVQTKERSLRGDLGVSVEGSNASVPGDDQWHDLSSNTLSLPPIDPYGPSRWIEIYSTGVNPVSWTISAEPFVVVSQAEGTLSGPDGDGDMEVRVELSIDWDSAPDTFGETTINISSSADYGTQFSMPQVVLPYNSTAAPTSFAGHVESDAHVSIEAEHFAGADAALAEMPAPDGEPGYLVLPGYGRHLSGVELVPAMAPSLAAPAGPHLAYPFYTFAAAPAGDGANLTLFLAPSLNYIAGRPLRYAVQIDGQDVREVGWIEDRPDGALPVGWERAVADGAWASVTGNWSVAPGEHVLRYWALEPGVVLMKAVLDLGGVRESYLGPPESVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT50</accession>
    <name>A0A6A6NT50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl hydrolase family 61-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_291176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT50"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025370416" evidence="6">
        <location>
            <begin position="20"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="7">
        <location>
            <begin position="20"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="32226" checksum="45EE954C587075B6" modified="2020-06-17" version="1">MPASKFIGILGALVSSAYAHGTVSGIVAGGSFFQGYDPSFQFQNPPPTVAGWTTDYLDNGFVAVSDYADENIICHKGASPAGTSVPVVAGDSIELQWTTWPESHHGPIIDYLAPCNGDCSQVSKTELEFTKISGVGPTDGSSNPGTWATDDLIANDNTWVLTIPASIAPGNYVLRHEIIALHEGNQEGGAQNYPQCINLEITGSGTNTLPSGTLGIELYTATDPGIFFNIYSSDLDTYEVPGPALLAGGSSGDSSGDGDNTGDGAEDDDSDPADDEEEPTSCTELRRRFRRRAGHGKNKRIVKFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT76</accession>
    <name>A0A6A6NT76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_290820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT76"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000178">
        <property type="entry name" value="Glycoside hydrolase family 16 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF55">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="123"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="439" mass="49795" checksum="9147A7ECC466D63B" modified="2020-06-17" version="1">MQSNCSSYEHELCTFSNDGIHARSESDPAPAPRRTRHKFKSYRLKGDYEQPWRSDKRMNRTKYNNYIIWGFFVIALCLSGYTWYLANDQASHYEYCLVMNDDFSTLNEDFWSHEINGFGTGSFDWTTTDSSNSFVDSNGLHIIPTLTNETTDITTDQIFDGYSLNLTRAGGDSSCTGSNNMACAIRSNATTGATLPPVRSARLSTKGKKTVKYGRVEVTAKLPAGDWLWPAIWMMPEDSVYGAWPASGEIDIMESRGNEVEYSEGGRDVVISTLHWGPTPKTDAYWRSSRGKALRRTDYTKGFHTFGIEWSSDYIFTYIDSRLRQVLYYDFKGKKNMWQRGYFAEQTENSSLLEDPWSHTGNANTPFDQEFFLILNVAVGSRNGWFQDGKGEKPWLDDSTSAAADFLRAAGKWLPTWGDGDDRGMTVKSVKMWQQGACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTA3</accession>
    <name>A0A6A6NTA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA damage-responsive protein 48</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_373834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTA3"/>
    <dbReference type="OrthoDB" id="3050608at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12083" checksum="21C8488BD7F96219" modified="2020-06-17" version="1">MDFVKNFGGGDKESSSSSSEQKKEESSGGFLGGIGDKINSAAGGGKESEKNEDMLDKGIDMFQEKVLGQGQQSNESAIEQAKDEKISDFIRDQYKSATGKDFPVKDKETKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTS7</accession>
    <name>A0A6A6NTS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_351749</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTS7"/>
    <dbReference type="OrthoDB" id="10263353at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02669">
        <property type="entry name" value="Peptidase_C19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033809">
        <property type="entry name" value="USP39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="12">
        <location>
            <begin position="114"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="236"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="576" mass="65489" checksum="3FD93B3FDFEC8ED3" modified="2020-06-17" version="1">MPKRQAAEPLEDAFNVGSPASKRARVDDEAETPEGADGASPPNNGRLMSPRKQDRQKIDILGADEAEHSEMEEAGATPGMFDGTDREQLGITEEEDEESALAAPSRQDAPAEGYTDLYLDTINRAVLDFDFEKLCSVTLSNINVYACLICGRYYQGRGPKSQAYFHALEENHHVFINMATKCVYVLPEGYEVHNKSLDDIKFQVDPKLPRSEVLALDKNTETAWDLANRKYAPGFVGMNNIKANDYFNVIMHALAHVPPLRNYAMLEDLSSRPQLAQRFGTLVRKIWNPRAFRAHVSPHELLQEIAQRSNKRFTLTLQSDPVDFLAWFLNNLHLALGGSRSKPGTSIVQRVFQGRLKVESQLITARADAGDRLRFEDAAVETNITHFLILTLDLPPAPLFQDELDPNFIPQVPLSSLLQKYDGVHAQEARAHRRRYRLLHPLPPFLLLHVKRFSANKFVAERNPTIVTFSPRALDVAPYVEPDPTVHPPGEPIWYDLVANVTHEAIKIRDDSVEGEAEKKVWRVQLRDRGRDEWFEVQDLYVEKIRPETLFTKESYLQVWERRREGQRKKGKGKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTT4</accession>
    <name>A0A6A6NTT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_366087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTT4"/>
    <dbReference type="OrthoDB" id="3353407at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="765" mass="87924" checksum="A80AEB99682AE1F7" modified="2020-06-17" version="1">MHEKQPSRRASDAPRPPRDRRPAVSTLAASLSRLNPLRLVPSRTSFRYERLPTFELAGGSGASSSGGGGGATLLGFRKFAWLPATAPESPGGSSSLRFGRPDRSFGWPRRLSPSRCRGALVLLVMLLALLGAGGYRRRLRRLEEEERRNHRDPYPWELFPRLNGFYNGIRDLVPFSEYVPEQVAVSVDAPPDFGPKGDEYVDHRDELPLDPVRFDPYPDYGSDEYLQDHFPVKQCFLDREEQIPVPDVYAYPGVPQNMTAPFFGSYRELGLTEDICFDRYGRYGPYGYGYDLDQGGAGVGNESESAGSEKVWEMVGERIDYRGIDWADAQRRCYEKNKARFESGDARDGKVKKLVPRQAYVLRTWAGYQYSEHQILNLRSMVSELALKSGGEYDVHLLVHVKDDSIPIWASEEVYNQTIRESVPEEFWGIATLWSEQLMRTYYPEPFPDNVENHANAPIHAVYRSAHFALQWFAQNHPEYEFFWNWEMDARYNGHYYEFHTEVAKWAAKQPRKGIWERSARFYIPDVHESWANFTELVEEETFTRQEKPVWGPVKFASDAVVETPAANEPPTSYLKDDFAWGVGEQADLIVFNPLFDPARTNWVFRDDVTGYNTSLPEPPRRAAIITLARLSRSLLAAMHDDVFRLRRTMFPEMWPPSCALHHGFKAVAAPHPVFFDRDWAPEHMDRVFNHPRRPHESPFGWGEHNHKGSSFYYNSGFSGALWRRWLGQRQNGEGGRREEEVGSGRLCLRPTLFHPVKREDGAYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU08</accession>
    <name>A0A6A6NU08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_396401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU08"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="409"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="622" mass="70618" checksum="1593E38F14316DDE" modified="2020-06-17" version="1">MIVRALVPNLEYRTVQEIWDKKAYKYKVVESSTAEEDDNKKTQDPSYFIDVKSNKLRDILRIVLRRVRGISLKGNKPPNLLYSYVAELEAHYGTMDSSPGNDIPKKHLSVLLDFIKRTYASTTERLVPLLDGGEITYDLLWALFKPNTEVYANCPEIDRPRCVKCNFGEERERTNRTKYFHLECRYLEWDGKLLGESTVVFEIERFRGVKSISLLNAFPLKYLPSEREARTELIKNGRNFLSYRSTHHVQYHRLAFYRDKYGTPVSVSVDGRVIVDAAYFRKVNPNFRLSAVESSRRTTNDGLLPPPPPPPSETGQVKNADVDVSGMKDEELLICSPVVYGFSLKDKLWVKSAVGFAVANIRPISWNPGSFAHLAIPRDKKDMLRAVAEAYSGGDSGPAFDDFIQGKGRGLITLLHGPPGVGKTLTAEALSELLCLPLYSISAGEIVSSGDLEEQLSRVFELASHWKALLLLDEADVFAEQRAVQDIHRNKVVCTFLRTLEYYEGIMFLTTNRVKTFDDAITSRIHMMLKYEPLSLVNRVTVWEGFLRKANAEYKKKDLEWLANKLFNGREIKNIVRMASALAGHKDGRLSLPQLKVAIAMREEFERDFKGAGAIESQHGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU11</accession>
    <name>A0A6A6NU11_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU11"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="15808" checksum="623CF5CCE4E75006" modified="2020-06-17" version="1">MERRVKGSVRASALVVVAVVAVVAVEAVDGRRVLGRPTPPGCGPPPGGSEGARSIVRSVSRPFFGLFFASLDASWKIVFGAEHERLFGCCLARSAGQVPTRRLDGTRQVFVDDGAGGASTEQGSEEVTHRSTTSNSQGGTRQSLRERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU31</accession>
    <name>A0A6A6NU31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_373563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU31"/>
    <dbReference type="OrthoDB" id="3946340at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="303" mass="33560" checksum="CD7FFB91FBF26F6B" modified="2020-06-17" version="1">MPAEAAGIVLGLRSHSQLFDTPPLETYTDGIVELVPFGRHVFRSSVPFGDADLLHWLWLLGNGATDKWYLAPETLAMKEINLLASAGIDTVDKIKPIRIACPARLELPRVVAGPALLCSQFASEDRSWLASRMCTPRVAVFCANDRSYISDEEVTGSEDEEKWSEKRQSKRSSKSAKRPAEPTLPIRARSSQQSTRKHSITYLTVVQTLQENISFPHGFITDNSPGASIFKVVRSGSREVAASTSFYEAGHAGWSTVFACAVREDDVQWLSRVGKDMIERVHSAAELERAETDGCTKKLKVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUS7</accession>
    <name>A0A6A6NUS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_423326</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUS7"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="219" mass="22917" checksum="32680CA240B876A4" modified="2020-06-17" version="1">MASLPTAPGTSQPRAQAPPLPPKAPPEKPAYIIEWEVPEGSSAKSATSSLRNALLATFDRVFPPYRTYFGRSRRTFLVIMVAIFAALLGLVIGLAVGLPGNCPAPSPPSAAPSDNTTPGTIISGEMTYYSPGVGACGQTHGAADLVVATSHARWTAANPNADPECGRRVRVQRGGASVELVVVDKCTGCAVDNVDVSPTAFQQLGDLAEGRVNVEWSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUW8</accession>
    <name>A0A6A6NUW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUW8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="8044" checksum="6D6ADB2CF8DA2BE2" modified="2020-06-17" version="1">MVQARRARSMIRGPRSLSLWASQTGWTSLTRRVKIGARNRTGAWRWTNVVTTGFDGGDRSRLQWRGWVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV13</accession>
    <name>A0A6A6NV13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA-splicing factor prp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_324624</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV13"/>
    <dbReference type="OrthoDB" id="440128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:001164">
        <property type="entry name" value="mRNA splicing factor (Prp1/Zer1), putative (AFU_orthologue AFUA_2G06070)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000304">
        <property type="entry name" value="Putative Pre-mRNA-splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13428">
        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="9">
        <location>
            <begin position="12"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="113"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="945" mass="104832" checksum="47E10DE471F775D6" modified="2020-06-17" version="1">MSGRKDFLSQPAPENYVAGLGRGATGFTTRSDLGPAREGPSEEQIKEALAKRAAALGQAPPTAYGAKAATGKDDQDDDDDDGRYADPDNEEGLFATGTYDRDDEEADRIYAAVDEKMDRRRKIRREAREAKEREEYERNNPKIQQQFADLKRALGTVSDDEWASIPDVGDLTGKNRRQKQNLRQRFYAVPDSVIAGARDSTQFDTSISADGNSTGGSVENSDGTVTNFADIGAAQNKVLQVRLDQAAAQGGGSGTESVAGTATNIDPKGYLTSLTKSEIKAGEIPVGDIKRARVLLESVIKTNPKHGPGWIASARLEEVAGKSVAARNVIARGCEFCPKSEDVWLEAIRLNKNGVDNHNAKIIAANAIKNNDRSVRLWIEAMTLENDQRSKKRVLRQALDAVPQSVALWKEAVNLEEDPADAKLMLAKATELIPLSVELWLALARLETPENAPVVLNKARKAVPTSHEIWIAAARLQEQLGNPNNMVGKLMERGVTALAKESAMLKREEWIGEAEKCEEEGAVLTCGAIIRETLGWGLDEDDDRAATWMNDAKDPIMRGRYETARAIYAYAIRVFVTKREIWLAAADLERNHGTKEQLWNLLEKAVEACPHSEQLWMQLAKEKWQSGSIDDARRVLGRAFVQNPNNEDIWLAAVKLEADNGQVDAARGLLAEARAKAGTDRVWIKSVAFERQQRDTDAALDLVTQALQLYPKAAKLWMMKGQIYQHELHKFPQAREAYMTGTRACPTSVPLWLLAARLEEQAGALVKARSVLDRARLALPKDGTLWTESVRLERRAGNLPAANNIMAQALQECPLSGMLWTEKIMHLEARTQRKPRSLEAIRKVDNDPGLFVTVARIFWAERRLDKAATWFEKAVLADADQGDSWAWYFKFLLQHGEDDKREDVVSKCVLSEPKHGEVWQEVAKDPANAGKSTEEILKMVVARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVD7</accession>
    <name>A0A6A6NVD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADP-dependent mannitol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.138</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_350031</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.138" evidence="4"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVD7"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05352">
        <property type="entry name" value="MDH-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF13">
        <property type="entry name" value="L-XYLULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00066645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00069279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="293" mass="31457" checksum="D9178D595F3E5EA0" modified="2020-06-17" version="1">MSDTAMNNGVFSLDNTKAPSESKVLPLFSLKGKTAIVSGAGAGIGLCVAQGFAEAGANVAIWYNSNKKALDRAAEIEQTYGVKCKAYQVNVTDPDLVKKVVNEIVQEFNGRLDVFVANSGIPWTQGPAINGEVSHYHKVVSTDLDGTFFCARAVGEIWRRQHQEGTDAFGNPLDNYTCGKFIATASMSGHIVNIPQLQAAYNAAKAGVIHLCRSLAVEWVQFARANSISPGYMATEISDFIPQETKNIWKSKIPMGREGEAFELKGAFLYLASDASSYTTGADILVDGGYALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVH6</accession>
    <name>A0A6A6NVH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="14">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_66482</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. PP-2B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="14"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVH6"/>
    <dbReference type="OrthoDB" id="5593063at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07416">
        <property type="entry name" value="MPP_PP2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041751">
        <property type="entry name" value="MPP_PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="16">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="510"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00053858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2455487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="550" mass="62993" checksum="4C8B4836C167B8E5" modified="2020-06-17" version="1">MDSSDPNFDHNQYIDNAIRAVNEKKPLPEIDFTLHTMEDGTQVSTLDRVVKEVQAPAVHTPSQDQFLSPQDRDKPNLAYLKNHLYREGRLTEEQALWIIKKGTEILKAEPNMLEMDAPITVCGDVHGQYYDLMKLFEVGGDPADTRYLFLGDYVDRGYFSIECVLYLWALKIWYPDTLWLLRGNHECRHLTDYFTFKLECKHKYTEAVYEACMESFCALPLAAIMNKQFLCIHGGLSPELQTLEDLKAIDRFREPPTHGLMCDILWADPLEEFGQEKTSEYFVHNHVRGCSYFFSYPAACAFLEKNNLLSIIRAHEAQDAGYRMYRKTRTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILNTCSKEELEEDTPSSLGGAPSPPLANMDPESTEYKRRAIKNKILAIGRLSRVFQVLREESERVTELKTAAGGRLPAGTLMLGAEGIKQAIHSFEDARKVDLQNERLPPTHEEVRRTSEENRHQALDRAAKEAEQDTGLATVARRISM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ4</accession>
    <name>A0A6A6NVJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dephospho-CoA kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_365247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ4"/>
    <dbReference type="OrthoDB" id="247245at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001227">
        <property type="entry name" value="Dephospho-CoA kinase CAB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="271" mass="30165" checksum="D56AF89A2E84D7D3" modified="2020-06-17" version="1">MLLFGLTGSIATGKSTVSSILRDPPYNLPVIDADVLARKVVEPGTPGYAAIVSHFAPSTPDLLVPAAECGGREDGPGGLGRPLNRPALGRRVFGGGDATVKDRKVLNGIVHPAVRREIYKAMLRAYLRGNWAVVLDIPLLFESGWERLCGTVLVVAVSEPEVQTRRLRERDPHLSEEDARNRVMSQVDVREKAEHALRRGPGAGVVVWNDGDKEDLKKEVERVMKEVQARSPKWWAWLLLVCPPLAGVTALMSFLKMWRIQRQWEQEKKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ6</accession>
    <name>A0A6A6NVJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM4</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM4</name>
        <name evidence="7" type="ORF">BDY21DRAFT_288602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ6"/>
    <dbReference type="OrthoDB" id="10069295at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="81"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="27846" checksum="918291B993879940" modified="2020-06-17" version="1">MDSSDRYLNPSALGTKEYWDATYARDLTNHATSTADEGTVWFSDADAETRVLSFLERLDDEARLRKGDLAEAEAKMMSPSSFLDLGTGNGHMLFALRAAGWAGALVGLDYSEASVALCEEILAARRERRRRQRNESAAAESGAGGAEGGDGGFDVVLDKGTFDAISLSDDVVPGTGGRRACEVYREKVVPLVKAGGGLLLVTSCNWTEEELRGWIEGAGEGGESGGFVFEDRIEYPRFRYGGKEGQSVVSVCFRRTGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVM3</accession>
    <name>A0A6A6NVM3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVM3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17932" checksum="F21FBFFC734E6EB9" modified="2020-06-17" version="1">MFHRRLVGRWLGLIAKGRERHRSSMVRRHQMGLEDDNATIRDIELRNCLLVAKPLARKSDCNVRVFELLSIPSEILLFHSPHAMFAICNDPQEVVLLKFTSRIGGVVKDTDPEATLFELLLRHDTCRPLMEIVHEDRLVPKGPWNTRMCTLARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVP1</accession>
    <name>A0A6A6NVP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_395748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVP1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="460" mass="50474" checksum="AA070637D86EB3AE" modified="2020-06-17" version="1">MVQVKSSSLSSMRAFRLLCCFGRLLPGRLYKAHTTAHFLTSSSFPLRRISTLSSPAHLVIQHPQMTQLAMETPYPPWPASIGPRPPPPPPVPETPTARRNVRAQRSVPALRGQRAQVEQNPAFRSLATRLLANELKTPGNLITALKTDLFGTFVTLRALAKAAVTPKDAAVTADSPPKTSGPGPGPGPSRPVPPRPARPIRADPSLESLTYEEALPTLGASPPDPASPLGVDLRPHGDYRAYLSETENRELKERVRALEHSLSSAYTVINSLHLSDGHGPASLASPHTPIKTPKRSDVAEEDKKSVKSVKKESGSAGSKSERVKKFFTFGKKPQQQPHLGGTPASPPVRPTPYSTMDVETFIGEPRDGEGVEILLRQFVTQLRAKFKHYPDEFAAEQTKIAYARLCLDGSALARMQHHIRATGLEQMTMTQFFMRLVEAHAEDMADHAFEELMLQILRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVW2</accession>
    <name>A0A6A6NVW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_75451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVW2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18882" checksum="5ADD86E549AE757C" modified="2020-06-17" version="1">MEYRVQKRVHIFDPDIPARTSAAGFVGFHALWGLWLRASKKPKTPRTGKQGPEIFSKFGLAKRQNCRRTAEYYVQGTYRPGLMNGAFAQYEWLFHQRIFPLLFCLKVTKPACDGRMYLRGSSHTTRCMRRSGMCADTFIVDGSMLVIDLTAETSNRGRELYNGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW86</accession>
    <name>A0A6A6NW86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_289001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW86"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF21">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="31"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="242" mass="26826" checksum="12B1DD838D0D8D0F" modified="2020-06-17" version="1" fragment="single">MPAAAAAAGEEEAEAEKALDRRTVRRLDAVLLPFLALLFLFNSLDKSNVGNAETAHFTRDVGLEPSDLNTAVACFYAFFVSLQPVGAALGRKYGMSIWVPSVMTLWGICTMLHIWVRARWQLILLRIAIGSLEAGFYPTTVSYLSLWYTRGEFARRLSVFYGQIAVAGAFGGLLSWAIFSRFEGEGDERPGDADDSDGAGWKPWQILFLVEGAMTMAIALAGFWWLPRSARSAWFLRPDERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWG2</accession>
    <name>A0A6A6NWG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">La domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_422427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWG2"/>
    <dbReference type="OrthoDB" id="439993at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08029">
        <property type="entry name" value="LA_like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12291">
        <property type="entry name" value="RRM1_La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="5">
        <location>
            <begin position="114"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="240"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="335"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="57963" checksum="C22159DC5E65E11F" modified="2020-06-17" version="1">MADDKVEVAQPSVAAQDAPVATDDAPTSNGASADITKASDAADEGQDAKETSESKPETDDKRESGVSKPAVSEDKSKEATSVESGDKGASKPQKRYTKFSKTDFNKNVKSDFSSLPETDDPEQIRKQVEFYFSDSNIPVDRYLFTLTGGPENKPIPVKTIHSFKRMRRFQPYSAVVAALRDSEMLVVEGDSNDATVKRKEPLPADAVGDGATTDGKGADGAKTFDPDRATKTFEDRTAPRSIYAKGFGLEGPSTQIDIERFFEPYGPVNAVRLRRTNPEKIFKGSVFVEFKDEAAQKAFLELEPKPKWNETELKVMSKKEYCDFKAQEIAEGRVKPNEWKRGGFRGGRGGGRGGSRGGRDGNGKRDERDWKGRREDFQKNRGGRGGRGGRGGRGGRNNGARDNKEEKKKIPVDERGVPIVHCTKPGDELGGKKRRASEDSLASSDSQGKKRAREDGTEPTSPAKKAKASPELQEEKKDSEATAGAQEVAEVTKPTEEKKESSSPGKKRARDDDDVEEGDAVKKAKTGEEVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI4</accession>
    <name>A0A6A6NWI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial</fullName>
            <ecNumber evidence="6">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_347844</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="6"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWI4"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000003">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="58"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="387" mass="41986" checksum="53E2DFB27C106FCB" modified="2020-06-17" version="1">MLATRSLAAPARQCLRQAVAAQRRAPAFFQTQKRFYSIPEQDKVAKFKGTKGNDGKFTVTLIEGDGIGPEISQSVKDIFAAANVPIKWEAVDVTPRLKDGRTVIPEEAIDSVTRNYVALKGPLATPVGKGHVSLNLTLRRTFNLFANVRPCKSIAGYKTPYDNVDTVLIRENTEGEYSGIEHVVVDGVVQSIKLITREASERVLRFAFQHADAVGKRKVRAVHKATIMKMSDGLFLNTARDVAKEFPHIEFDAELLDNTCLKIVTDPIPYNDKVLVMPNLYGDILSDMCAGLIGGLGLTPSGNIGDECSIFEAVHGSAPDIAGKGLANPTALLLSSIMMLQHMGLNEFADRIQNAIFAVLAEGKTITGDLGGKAKTSEYAEAVMKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWQ4</accession>
    <name>A0A6A6NWQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWQ4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="20386" checksum="B24D68C44DCB485C" modified="2020-06-17" version="1">MQRSQPARPLSYQSTARPDLRVMPSSPEPPKSSIASTSPLHPHDSGFFESSSSMGNDKRAPQDNDSSSKSQVLGAHHHYSSTSSCHGPLHEDKWNSSNHWENPLEPTSKAAGKKAMRGDNNVAQGSSDNLPTTEMAFSSPSHLYASKAAAGNMKLASPAGHDAADHLDARYFSFVQAFSGSVYFSAKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWX5</accession>
    <name>A0A6A6NWX5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_65667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWX5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="19658" checksum="F4003CF1806B18CA" modified="2020-06-17" version="1">MKLHVLAPYRQPCKRQGGEGGDDGATSGREGKRGIRTKSSAASKAGFFCCDATAGSDMSIRAASSALLAVCGRAGRSSSFGARKGFRETGRLGWLLALLKLRGEGSAGDGKAGEAARLRKGLLEDRLSVSPGEGRRSIIDILAARAARATWLRAIGTRTLAAACASGTNVGTTKDSCRIQQAGCRGQASAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX18</accession>
    <name>A0A6A6NX18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_348747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX18"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="6534" checksum="B096DFBD50A5D5EB" modified="2020-06-17" version="1">MVWKVGLLWGLGDWKACGGWAGVGVVSFLDSCLAGLVQGFMWGGGAYGVVALLCCACLRVLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXH1</accession>
    <name>A0A6A6NXH1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_372550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXH1"/>
    <dbReference type="OrthoDB" id="3197614at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130:SF1">
        <property type="entry name" value="SPINDLE POLE BODY-ASSOCIATED PROTEIN CUT12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="583"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="693"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="628"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="716" mass="73622" checksum="774A0333E8384991" modified="2020-06-17" version="1">METASLTLAHNHARLASQETQKANASLASEEHELAAGEFSKAAKDIHDYEALRVLKLLEGHHQHLAHIIKAQSTRLPAPASAEQPPKPEPAPSSTQQIVDPPAANAPSAPQTPTPAATSPEPPAQPPSTTTPARRTLKRQSSSSIATNLATARGIPGQQHQQRRGTPITPTVSRDSAGGRILRQQRENDGSLQAAAERRPSTRRASYQNPEKTKDAGGGVSGGSTATNGAALTAPHPLPGSEEPFQRFFNTFETLFTKLSAPLAFASLPLNPLPTYTANNAEASSARSPKPPSNEVPVPRTSQPPPAVDPSDPDLSTLISRAALRALRDDHPALGPGESFYVVPTSGGTVSYAGIVARGDGSNSAGGVGGTGDAITGAHLAEVPEEEAEGLDDEFVDASETPYAGAGGSASPTSLRAPHARDGHHGHHHERGHSGASSRAHSRRITGGSSGGGGAPGLHHAGGSSLGASTASVATMTPAAAGAARGRGPGIGSGGGGGTSSGRKTREELELENAALKSVLDQQSRRLHMWEAASQSQSAALAMSFRAWRDGGGGGGGGMGSPGQQAQAAAEGVPPVPRIPERFREAGGTGTEAGMGGGTTETKGTEAEGKSGAAAADQEGDAAATPAELVSEHRLRELEEQLAAARRDNEQLARDNERAARDLARQEKMVLRYRELWERLKAGAKRRERAAAEAAATMAEAVETTGSPVGEGEEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXW3</accession>
    <name>A0A6A6NXW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Vacuolar protein sorting-associated protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_386505</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the retromer complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the VPS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXW3"/>
    <dbReference type="OrthoDB" id="9976382at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030905">
        <property type="term" value="C:retromer, tubulation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06891">
        <property type="entry name" value="PX_Vps17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000046">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000034">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014461">
        <property type="entry name" value="Retromer_complex_Vps17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053055">
        <property type="entry name" value="VPS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037907">
        <property type="entry name" value="Vps17_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011791">
        <property type="entry name" value="Vps17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="8">
        <location>
            <begin position="167"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Sorting nexin/Vps5-like C-terminal" evidence="9">
        <location>
            <begin position="298"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR011791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="596" mass="65458" checksum="776E3862536FE2E0" modified="2020-06-17" version="1">MDYSAVTDPDHPEGPSPWASSPQHSRTSFGHPAAADIPSSPLPPQSPYADHGFSSDHDTVDDSLKAVKSVESSENETRTDDARASVHQLPQPPQQHHHQQHQPQMPQTPQMPQTPQHGGPKRGPRQNAPHHKLQAKVTGLERTGRKDLILRFDVYTNLPKFRTTQFRDVRRTHSEFQKLADHLISANPEAMVPAVPPPVTSAGVGTDEDEARVKASFQRWLNTVCGNEVLMRDGEMVYFVESDFGYSPVVRRKQPATGVRRKYLKQFAPPPDDTPELADARPVVKMFYLGTMDAGQKLDRVVKCRRSLGLSEADLGVKLGTMHAQETHPGLANAYRKIGRVIQITGDYHAAQGTAEATTLGDPLAYHSSDAFIVKETLTNRHILIRDLLQAQASTRSKLAAADRLKASSSVNRNKVDEAITALDEARSHEAFLTQKVARVTSTLVQERRKWFARTAADARAAVRDYVVRQIEAERRTLATLEQVRPDIRAIDASGGLSRLGREAHPAQRRASLASSQGPKGDAWSGVPRRVGDGLNRSLASGSVKEEGEEEEQEAQGRKRAVSKSGVGKAPGGLEEDDDDKVDARNAASRLATTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY39</accession>
    <name>A0A6A6NY39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YL1 nuclear protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_347250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY39"/>
    <dbReference type="OrthoDB" id="3942062at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="690"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="532"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="760"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="811" mass="86551" checksum="031B1879E00C7C6A" modified="2020-06-17" version="1">MASDSDASSSDGEPEQPMVLARSRRANAGSRMSNLIAHLDDETIKADLDLLEDAPDDVEFGGEEAEDEGDVSLESSDEDEDEGEGGDDELQGERELRKQEQQAKAADAKKRKAQNPLLKPAAFLKKQKVGGDPRSTPGPASTADVTADSSASGTPAPRKKRSERVSWIPTTDDGPVRTSARSTTMASRADLHERLREKEKHRLSTLAIMRAAEQRKETSKPRKVMTQAEHLAEAARVEKENSKSLTRWEEAERKRSEEQKAKLEAMRNRQMEGPFIRTYSGPSLWLDDKIKIVGKKALIEEVAEELIAMEVRNCGSVEVPGKNSEQTRTSFAGKNAEDNVAEHQIADGNAGDGKTDGDKEVEVKAEPTPMDTDAQSVPTITESEDPLSNVVPKPPTPLPASTSPPIVPPMAPVQSPDGAPAPPEPTSAASPPLVAAGAASAPPMSTKPSFSTVPPTTSAPKFTSTVDPPSLLPSTLAPQPFSATPATVAPIIKPPEFVLYETGINFNAPGPAQEGYSGLLNGIHFWASMPPEEKNENERSSDEQPVQPTEPQADRSPANGPTSGPAPTTALPATATPVTATHISESSPLPNSVPPTSTSPPTPANAPAPAMTAAPNLVKPQPQASVQEGPQPLPRPVKDVAARNLVILNGFHFPQIRAKDRDARQREREAILRPLLGWKNYVKPTKTAPTFCAITGLSARYRDPDTGLAFADEYSYKSIRRVVDGSCMWSNLLGCFVGPVYDDGLGRPARGVPDKFWSKTQEEPKVNVTAAGKRGENGEEEDEALGGASGAKDGGQKDPTQAGASTPEVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYC0</accession>
    <name>A0A6A6NYC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Armadillo-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_393787</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYC0"/>
    <dbReference type="OrthoDB" id="2017782at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000167">
        <property type="entry name" value="RNA binding protein Jsn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052645">
        <property type="entry name" value="Pumilio_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093:SF1">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="455"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="PUM-HD" evidence="7">
        <location>
            <begin position="607"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="669"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="705"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="742"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="533"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="960"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1166"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="977"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1012"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1166"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1198" mass="125995" checksum="B95A25E2B47E2004" modified="2020-06-17" version="1">MGPSQRSEPHHMSINYLSQLAQSQAPSDSSPAATSPSDAPAGATRLGAGSPSHEFGSRLYSKRAREIQAQEGLGPQVWGPPTSGNSTPLRETIPESPNGESFPDFNAPPGLDSIAAGAVPSTTTRRTRAGTLPSRFSPATGLAPGLTPSSTLSKSSRPTPSTSPFKPGSGTPAEGSGFGQPPNNSAASKSALLSRLRAGSMPQRASFLSNNSNPFGPSVFSTNWGGARDRSTTLASIQSSNGPTSPSHSSFSKDGFNDTDVKTLDYLGLVDTPQQSRAQLAQPSDVESLLSEQRSTVGLQPAAIADLAALTKTANRFRSYSVNAKERYADEEEDDMSSMARYAANYSGSLTPSAEGNAAAYAIQEAVRQHNLEVQAFANFATANRPRARTAGVLDSPSTRILRSYMPTPSRLDSSMSASDMQVPEEAEFSGLTEAAMDTPGATGGDENTLEGPTRALWLGNIPPSTTVSSITHIFGEIGPIESSRVLTHKNCAFVNFENVADAMRAKALKNGTEVFPGAGPVRIGYAKVPSASATPNTNGLYPSPSPDPMAKGADGASANVTGSRAAGGGRTDAAVGAAAPPPSAPALPDIRDEILHIVKELGSTEVDGKRIEKLVTRAVEFDDYRTEIPPIGEPSHNRMHDAPRLREIRKRIDNNACTQAEIEDIAMGMLPEIAELSSDYLGNTVVQKLFEFCGEPTKEAMFEEIAPHMAEIGVHKNGTWAAQKIIDSARSERLKQMIVDSLRPYGMALFLDQFGNYVMQGCLRYGSPLNDFIFETMLSRLWELAQGRFGARAMRACLESHSATKDQQRAIAASIALHSVQLATNANGALLLTWFLDTCTFPRRRTVLAPRLVPHLVHLCTHKVAYLTVLKLINQRNEVEARDTILQALFFSPNDQVLEAILSDQACGATLIFKVLTTPFFDDKIRPEVVQNVRNVLLRIKAVPAQGYKRLMDEVGLRDGHHHHHHEGSRPGSKHSSAAPRDQQQPASAAPPADPSTGRPLFYPGMPGPQGPAAGPYSAAGADLQRSGSVDSTGYDAFPTLNGAFPPGMGAPGPMGAPAPGPMGPGYQQAAMLAAAAAGRSGAGAGFYPPGMGFDANAFRGAGNGNGGAATSVPPGLGGMGAGAAAGAPMMPQAGGFAGPQAFGMMNGGGGGGGGMYYPMQYMGPQQQQQPMQQQVGGRSRARMLEMRASPAAAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYJ5</accession>
    <name>A0A6A6NYJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYJ5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025689787" evidence="2">
        <location>
            <begin position="19"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16198" checksum="53D9ADD5AFB70F16" modified="2020-06-17" version="1">MLLPSSTLLLALLAIVTATQSTARGHVRSDGVLLEAKSPGIEITLVTPTKTSISPSPKLKSSTPSRVSTTSRSSTTSKISMASTTSRSDTTSTASETKGRNQHPTQSTISTGRHCPYPYPGETCARQTTTVGNDGELSNGPHCPYPYPGETCTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ38</accession>
    <name>A0A6A6NZ38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_31974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ38"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000554">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43832">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43832:SF1">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="351" mass="39971" checksum="2633F69CED289883" modified="2020-06-17" version="1">MSSGSYLNAVLDSGILPHYVIRVGIRRQLAQRVAMIRSSSLAAAYESKMDYIKALRTRPMAIETDTANKQHYEVGTGVLKACLGMRMKYSCCLYDLESRNGPGSLDEAELRMMDSYAERAELQDGMRILDLGCGWGSLSMYLAARYPGSQVTAFSNSRTQKVYIDSVAAAHDPPLKNLTVVTGDIVNHEFEPESFDRVVSIELFEHMKNYALLMSKVSRSLVPGGKLFVHLFAHKETPYDFDGGWMTEHFFTGGTMLSADLLLYFQDDLKIRRQWWVNGRHYAQTCEDWLSNTTKGRKEIWPHLEETYGKDKASAWFYRWQIFYMACAEMFAYEGGDTWGVSHYLFEKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZB4</accession>
    <name>A0A6A6NZB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZB4"/>
    <dbReference type="OrthoDB" id="4207123at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42095">
        <property type="entry name" value="YALI0C12166P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42095:SF1">
        <property type="entry name" value="YALI0C12166P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="21140" checksum="9E6EC543ADB184A8" modified="2020-06-17" version="1">MPTNRPFLSNFLAAFRAHSALQKAASPSSSGSNAPCQAPYNTYATTSTTTATATADAFSSSSSSSAGAESRTAATTPPAAKSGPAAGATTAAVQAAGQFHAQGPRNHGQHHHNHHHHHHQQAASSPYVRSPASPTSGTFPLGGSASRQRRGSDSSSEGFRDAVGAEKWYIGGRTAAGEERFYKLGMVKKHRSIDRLSLDRLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZG9</accession>
    <name>A0A6A6NZG9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZG9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025395853" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8021" checksum="0C0A1C39AADAF5A0" modified="2020-06-17" version="1">MWGPVSLVLHVRLLVACWLVPVRMPSVELVEQEELLLEESSGTPATITASYLRAALLPRSPRSLPMNQIQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZT8</accession>
    <name>A0A6A6NZT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZT8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="18308" checksum="5D6CF64FCCBE576A" modified="2020-06-17" version="1">MEASTSPPLPSPLLALLFHPPPFTASPPPLTRPLLLSGKPPRPTSCRARQPLFPLPFSSVPPKLPRFGGGCGRGTDVCLAGAPRSRPGPWTAESRRAHMGRPGQASGARPRELPWAALGAWPGEGGAGPFGGYGYVGRTGQETWRGVAGCQGRRWLLLRKLPLAYMLRTLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZX6</accession>
    <name>A0A6A6NZX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H3-like centromeric protein CSE4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">CENP-A homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">CENPA homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_364013</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of centromeric nucleosomes, where DNA is wrapped around a histone octamer core. The octamer contains two molecules each of H2A, H2B, CSE4/CENPA and H4 assembled in one CSE4-H4 heterotetramer and two H2A-H2B heterodimers. Interacts with the inner kinetochore.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZX6"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000087">
        <property type="entry name" value="Probable histone 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="71"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="18866" checksum="FD47D984E07E05CC" modified="2020-06-17" version="1">MPPYQRQVKPPGGRPGPMRYVNATPSKRPRHSAGGKNVGSGRKAQKTVGGRRVSGVEPGDPVPRKKRRYKPGTLALREIRRYQASTDLLIQKLPFSRLVREIASYMVIDKDLRWQSQAIMALQEASEAFLVHLFEDTNLCAIHAKRVTIMQKDIQLARRLRGAWGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZY7</accession>
    <name>A0A6A6NZY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glucose transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_392122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZY7"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF17">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="23"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="620" mass="67391" checksum="EC946B1586DFE4ED" modified="2020-06-17" version="1">MPGKFMFTKPADEAGKTWPAIVIGLFVAFGGVLFGYDTGTISGILAMDYWKREFSTEPDGEITPAQDSLIVSILSAGTFFGALFAAPFADILGRRMGLMAAAGLVFNLGVILQTASTRQPMFIAGRFFAGLGVGLVSAMSKSTNSVTRASGLRSSAGGARSPRRFVVHLFGLAETQRVYGKIAGPGRAGRGARPGRRLESIAALVSGLRAQAGLARGNHDSSACDGPEPHSETAPKWIRGTIVGAYQLAITIGLFLAAIVNNGTKDRDDSGSYRIPIAVQFAWSLILVIGLIILPETPRYLIKRDKYDKAAKALSKLRRLPPTDPAIVDELAEIQANHHYELSIGQASYIECFKGTVGKRLLTGCLLQALQQLTGVNFIFYYGTQYFENAGFQNPFIIQVITNSVNVASTFPGLYLVEKMGRRNLLLMGAVGMCVCQYIVAITGTAADFANLPAQKAAIAFVCIYIFFFASSWGPVAWVVTGELFPLKVRAKCLSMTTASNWLLNWAIAYSTPYLVNDGPGNANLQSKVFFIWASFCFVCISFVFFLIYETKGLSLEQVDELYGMVHKAWKSKEFRPKIRFQDVDQIGENVRGMSLADAAAQAERKRSVAHVEGQQQEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0K9</accession>
    <name>A0A6A6P0K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_385789</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0K9"/>
    <dbReference type="OrthoDB" id="436262at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000272">
        <property type="entry name" value="Condensin complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000920">
        <property type="entry name" value="Condensin complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="87"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1043"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="829"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="908"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="829"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="853"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="946"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2457530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1226" mass="136063" checksum="E4E67721D80481A2" modified="2020-06-17" version="1">MDARVNFDINDSLKQYLSDPTSIATPEAASALADCETDPESLTSGLINGALNPIVEAVAEHPDALTRCENFDSLQFLLKYTSFLPPAALSKILDLVVSGLSAESDAAHADLEADEQDAVQHHKQLLEMFGFLLQWTVAAVETKAAEKPASTTGGRGRGGGRGGKKGAAGGRDTTWDSLAQLQTALDVMSKVLKLKLARIFLTTSERDTFVSLFTRPAYLVLESETRVKSTSIRMHVFKVLCIAVKHHGHAFGAQTSIIQNLSYFEHLSEPMAEFLQILAEQYDYPQLTEEILRELSNKEFNNNDLKGPKSVSAFIIKISELAPRLVIKQMTLLAKLLDNESYTLRCAIVEVCGNLIAMLSKAEGEERSENSKGQINAFFDVLEERFLDVNPYCRCRAIQVYSKLCDLETKFPKRRQAAAELATRSLEDKSSNVRRNAIKLLGKLVSTHPFSVLHGGLLARKAWNERLEAVDAEMNALKPPQELQEKTQDTVDEELLDDATQVENKESSEPAPMTEQQKAAALEKAATEAATSEMMNKLQLTRRYYLEAVRFIDVIHEASPTVTQLLSSKNKSEVIEAMDFFVMIDAYKIETSRTGIRRMLRLIWTKGNSDEGKGVQSHLIECYKSLFFDAPDSFSPNDAANYVARNMISLTFGATPAELTSLEQLLSTMMKENLIGELVIQKLWQVYGVQRKEISRNQRRGAIIVLGMLALADPEIVVKEMEACLRIGLGELGRRDLGLARYTCIALRRINAGAKGKEVAGRPAAPVAKLPNDHAVLVRLAAMCEIISDSKEWFGVAEQAIGAIYALAKHPDTLCSEVIRRKTKYVFTMQQSRPSSSGTSKSVVEESTISSKPSEEPEKAADDNKRPTQQRAASAMSQLLFIVGHVAIKQIVHLEVCEQDFKRRKAEREKLATSGDAASSRKSLGAGASPTKKAGSKKDGKPAEEPSPEDELDLIAGTTEDDFTDAIAHIRERELLYGEQSLLASFGPLAHELCANNTRYDDATLQAQAALCMAKLMCVSSEYCEANLGLLLTILERSKDAITRSNLVVALGDMAVSFNHLIDENTDFLYRRLNDKSPSVKRTCLMTLTFLILAGQVKVKGQLGEMAKCLEDRDQRIVEMSRMFFQELATKDNAVYNHFVDMFSLLSSDERLEEDGFRRVIKFLTSFIEKDKHAKQLAAKLAARLPRCENERQWNDVAYALGQLQHKDEDIQKLVAEGFRVVQAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0T9</accession>
    <name>A0A6A6P0T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DOPA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0T9"/>
    <dbReference type="OrthoDB" id="9970095at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="177" mass="20325" checksum="2515E6AE352F6452" modified="2020-06-17" version="1">MADPSLYAYPSPLEGWQGLPPLPDENAEDGKSYINPPASRSPAYDSFVTPITNGVRGGFDIHVYFLHTDPEDVKFAHELWERIRREFPELRIYQIWDNPVGPHMVGMFEVNLFNPEQFGAFIPWLVINRGPLSALIHPNTGDDERDHTQRATWMGQPIPLNLRPFKKMKEAKKQAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1G3</accession>
    <name>A0A6A6P1G3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pantothenate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_16773</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1G3"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24123">
        <property type="entry name" value="ASKHA_NBD_PanK-II_Pank4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000115">
        <property type="entry name" value="Pantothenate kinase PanK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.510:FF:000005">
        <property type="entry name" value="Probable pantothenate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00555">
        <property type="entry name" value="panK_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="501" mass="54002" checksum="25CCFB66A64A7C6B" modified="2020-06-17" version="1">MPGGSSAEEATRDAAQTSGTPAARDAPPIAIPSDVANSSTTSLPSSGGGHAAGKRPQLAGTAVATDPARIESAISHPGTVRINVQGAFIVEDEATTPGGSTVDEDFKHENKDIRLPNHTAVVSHIAVDIGGSLAKLVYFSRETGTDKSKQPEVELGGRLNFLKFETDKIDACVEFMRRLQRDHHAANGHGGPELCVMATGGGAFKYYDKIRDALGVEVLREDEMECLIIGLDFFITEIPNEVFTYTESDPMHFVDARPDIYPYLLVNIGSGVSMVKVSGPRQYERIGGTSLGGGTLWGLLSLLTGARNFDEMLRMSDRGDNTAVDMLVGDIYGQGYGKIGLKSTTIASSFGKVYKMKREAERDAEDHGGLANGDAREGEANGDGGGGKELGMFRAEDISRSLLYAVSNNIGQIAYLHAEKHNLGHIYFGGSFIGGHRQTMNTLSYAIRFWSKGEKQAYFLRHEGYLGAVGAFLKRQPRNWGRRNSLEALHPIAKSMARPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1J8</accession>
    <name>A0A6A6P1J8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371276</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1J8"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="143"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="357" mass="39004" checksum="D094B3A9FAFDF01E" modified="2020-06-17" version="1">MADTPTVRWGIVTTGLISSWFVEDLALPRGDAKAKHVIQCIGSSSVEKGQAFVKEHIASLSPTLYGTYDEVYADPNVDVVYIGTPHAFHKKNCLDAINAGKHVLCEKAFTITAKEAREVFAAAKAKGVFVMEAMWTRFFPLMRTLQKLIHEDKVIGDVSRMFCDFGQAKELASLGPDSRFKSLALGAGTLLDVGIYSLTFGLVTLDPGVGESAEMPKIAAQQTLSDGVDIATTAVLLYKSGRQGIVTSSALFKTPDVFCRIEGSKGYITVEGDAVSRPEYFIVHPTVPESKGGAPSKRYDFENPKRGFYWEADAVALDVAAVKKESSIMPWAETIRVMEIMDEIRRQGGAKYPQDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1P1</accession>
    <name>A0A6A6P1P1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_302965</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a zinc transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1P1"/>
    <dbReference type="OrthoDB" id="5382797at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904257">
        <property type="term" value="P:zinc ion import into Golgi lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF5">
        <property type="entry name" value="ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="554" mass="56631" checksum="F3480AA011218733" modified="2020-06-17" version="1">MASPNMPLPVPPRTPTPPPEDQANAAADTAKPQEITIPEYNPDALSPMSAGFPPRSFGASLGGRLGGGGGAGAGGSPLSPLSPMSVYSPMSIGGSSDGGGGAGGSPSVPLSAGSVISAGGAPNPFNFQTVQYTAGRPSAATKSDLGRRRGHKYKHSSVSHQIFLEPPPGRAPLQLPASLPMPTARECWRSMSREQTLRAAWCFCHLTVALLVQQGAHGSLAVAALSRLLFFDSVGAFLCVIVDVGGNFEIWKRSSVQWPFGLERLEVVVGLGMAVALAFLGLDIISHNLNHLLAHRGGHAPHMTHAHDGSPAPGTGPTSPLDGAGGPAHADRVSPGSVDLAALAAIVATLTSALALRNHARVGRVMRLDSALLAALPLPPLLANPSHLLTLSCSALLLLLPLLSVGVYAWLDAALAGVMAAAMVALGGRLGARLASILLMSYGAGGGGKGVEAVLDEVRRDESIVEVQEAKFWQVHYGLCQANLKIRVKAGAAAGTADGDQDAVVNRVREKVESLVRNRLGGGYGRGSGGVRWEVSTQVAVDTSGAGGAGTKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2X2</accession>
    <name>A0A6A6P2X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_411971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2X2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="314" mass="36725" checksum="97D985A3A9C01D05" modified="2020-06-17" version="1">MDMLINKAKVKDGKYNRRANILDAVKELNIGLSRAEEFYPSVIDQVRDVISTQLDWISPELKDTLVEAFERYQSREFVLLALLGLVSKLRKLQIRIEGLEPYLFARYFATCIAQIRSQNARVFENLRQLTIEFPRFWSQHRSKKVEVNPAVVLNTISSISLLPALEELTLAGYIGIYAKDRNKHSHYFRKPGAEAIGTLREIWVDEDKYREYDWAQFEMRRERGIWVDVDEYREYSEIHRELALFKFPLNALCTKHASTIQRFVIPVRLLSHPFEVCPYLHPSGRVSMLEMLPESLEVLEIDCEAEFSLNIPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3V1</accession>
    <name>A0A6A6P3V1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3V1"/>
    <dbReference type="OrthoDB" id="5424021at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="20251" checksum="A1291CF006390AF1" modified="2020-06-17" version="1">MAPAVAGDNNIWAQMAYTPPRGPCNHKQSLLSQCCPCLRFMLHPVKAMTSFDCDGCGHHASFHTMENQAEDAIVRRWESEARLRQQQQQEEEEAAAAAAAARPRKRPRRMLESVNRATAAQQRRRNNNALDGALDDWDSETERAEGGRVVELSDGTSQPGAAAEDTVVVRAGRGGGGRAGSGKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y6</accession>
    <name>A0A6A6P3Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Y6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="65" mass="7248" checksum="D3907DD3DA7DC376" modified="2020-06-17" version="1">MPRRTDQERPPTRSQPATTRPAPARTGLPTYTPYCATYLPVWYAQRASERAARTAPTPPAPAQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y7</accession>
    <name>A0A6A6P3Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_341103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Y7"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09487">
        <property type="entry name" value="SAM_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="122"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="122"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="807" mass="91178" checksum="9BE1DE478D52EC00" modified="2020-06-17" version="1">MASQALVDDLSRLGLAHYVDTLHQHGFSSWRALLGITESDFQKMGFKLGHRRLLQREISKFRSVPSSPSLVNRGYSGDESMLQTDSAAQDETSQFSTQTDQNKDGQAKRRYRRHPKPDPNAPKRPKTGYVNFADHLRTDPTISSMPFADITKEVGRRWRELPQAEKLEWERKAAQAMQIYEFQMEAYRRTDQFKEYQNYLEDFRQQHSQTIRIKNDSSSGPSRQFISPDAPFPHKAALEHSQVDPLQTRNEESLDLTISTALDDLSHLRQRLLKEGGGICSQARPPPENAIRQRLHNFLESSGALVFVMSHEEVESMLYEIYRQGTPAGTFTFAEVMSLAAVGGRYGIDSIAEQSKISWCGSALTDVDEAMVKANYLRGMRLLLIVSFFCLLENDLVARHLITAGLQIARQKLPALEGDLEQKERDNWKKVYRSLMFVDGWLSYTLGYPSRISWEDTSYACSDSQAIPASIEDAVHWQVSQIGLVCVDIHKTFECTKRVTTDTVLYLSQRLAAWQDDLPPFMQLGNFANQTPPGSDLSDSRNRTILKVHMLYLGAVMLLYRNILLLSVELPGSAVKEPRSNATLSMPVEAIQKCRVECVFAARQIAQVQKLLHLDVYICHCCWILLYWLSSACSVLLFGISEKLARGDYDGILDEDFSATQICLGILEQCSADPAATKSFANLSPLHSRLFAIRTELCRIKMIALDPSIRAYAHSSEAMGPAMFGTSPVSLPNTSPQAVSIDHLLESPREQMSTKDGDSEFKAELKGISNRLLELLHDPFDRKDSLSEEETGKVRMSDGNYLVFWWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P448</accession>
    <name>A0A6A6P448_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">XPG-I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_341288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P448"/>
    <dbReference type="OrthoDB" id="2959108at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09870">
        <property type="entry name" value="PIN_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041177">
        <property type="entry name" value="GEN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18380">
        <property type="entry name" value="GEN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="129"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="545"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="648"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="780"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="572"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="648"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="666"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1037" mass="111508" checksum="C2DDD3619681A410" modified="2020-06-17" version="1">MGIQGLLGELNASPTAASSRRIALASLSSAHLAAHNRPLRLAIDISIWLFQVRAGKGGTNAPLRTLYYRILRLLSLGINPVFVFDGPHKPPFKRNKRTFGTGGDGPASLAARTGAGGTDATLFARQVLEKFGIVVHVAQGEAEAECAALQRAGVVDAVLSDDVDTLMFGCGVTLRNYNGDVKAKAAAAGGEGSAAMSNKTPTHVDVYVNMRVPHASATAVAEATGTGVDKFATSLDPAGMVLFALMSGGDYIPQGIEGCGAKTAASAARAGFGRELCSLRPSDKAGMDAWRERLRHEIRTNESKFFRSKHTKLKVPDNFPHAEALRFYMSPVLSKPETFELVRRRLEAVERAFDFDYVGLRRFTLDAFDWGCLSGAKHFIRSLAPALLVRNLLQCARRRADEEMGQGRSTDAASIGTDPDALKTQEAKYVAKIHSRRTHASTDSTPEIRISYCPLDIVPIDLEAEEPDDNYQFGDGLHDPLAVDTEGAVEPLPFDALEDMADDGEPSSTVPMGAGTRGRQRTYDPSKLHRVWVLESVIKSGAPVSFEDWQGGTGNPAPSSQGSQGGRHKRGASTTRASSSGAEGAGRAKRGRKVRPAKDVQQGTLNRFAKVSKPNCGLSPIKDYSPANAVSGSRPVLPSKGVQILDLSASTSKSTVGVSGSQSAPGEEKSRPNPREPTKNTPAVDLSQKTPPRHRRRAESSAPPETGHRTRQTSITSFMSPSTNRGFSRSPRSPVGWSRSPRRPPTPTPAPTKTTGGTFDEAIEIISSPELASPAELWGSKQPELGEGRPKQKSNSVRSPTRTSDCWEGPARARGIFMRTQSENSTMSSASGPMIFQVNTTCSVLDMTGIPSSQAISGRDLHIPTEKNVVQESRLTRKKANFADCQESARDEDLTVLRNSRPPRGQHLSQMSGNIFRSRSQPYGAASSESVQQAKSSYTSLYTTSEPASSHFSCMSSVSLPNPPSSILQTSSRERFVKVRESLEGAWKLVDVDDGKTHGVSLQEFAGGVNNSVSMAIHGRSAPWKESEVRVLDLTHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4I5</accession>
    <name>A0A6A6P4I5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sin-like protein conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_370428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4I5"/>
    <dbReference type="OrthoDB" id="340681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="426" mass="45219" checksum="1AE004715A105318" modified="2020-06-17" version="1">MADTDNDDDPVIATYDVFITPPPAPPSTSFPSTDENAAGSGATPAPETRPPAAADNNHQIYLFQYPNRPRDQPYKHSNGSAPLELRLKPCSGFVELDVPIDTAAHFDRRRAVVWGEALRCAAGGGGGGGGGVGGEGPAGAGQASFGLAAGFSLPLGFNAGAGRPGGRGGGAVGPVGGRGGAAGEVAGDEVNEDMIEELLDNFPAANRQGRVLNRQTLGGQIVTDEPDKPVYMLGAFRGKELHLTKLSGVVQLRPQFHHVDAKAHLDKISATTRNRHAGGEPAAAEPLRSTEPRMMQMSIKQTDPDGASSAATREYLQVAHEEPWQRLAYMDEDTVEAYHMYHEKLFLQDTAKAQRLVSSMTNDEYLDAISAPRHDPSGRVKKKPLTKKQMRAVELEVMSDHEAEGEAQADVMAGAEGETAVDPMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P523</accession>
    <name>A0A6A6P523_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hamartin protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_339735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P523"/>
    <dbReference type="OrthoDB" id="6022054at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="415"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="887"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="626"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="686"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="928"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="998"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1029"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1103" mass="125739" checksum="FED88961DBF362F8" modified="2020-06-17" version="1">MLMKTLVRSLNATFATPVTHLPDEIQHAIEQFLDANENTIDEYDASRLHDDLLCTYETYVDSTQDKLAPFICALRMLRPVMREQQLAEWWELVIRPAVDSVGHKREVIDEAREFLLAVLVFDAERDSAGDKARVSRHFLTRLLDSYRRRTKIPPAAAEETITPESEFIAHELESVLVAFGRRKPKELLVALDELLVRKDDRAQVLALLCAFVRVQPPHLYLVLETSLIQHLYKCLMIDTSSTVVYLALTNLIMFLPHITSALVGLMPKLFLVYARLLCWSRIEPSSPEQYQNEAPEEVEDIAWEKLEGTNQDNSEPAPEIMHFFTFLYGLFPLNLMSFIRKPRKFLKGINFPKADEFDLPQDYIRAQTEKYRENHLLHPHFFTMQIEDELAENRWVKTDAADLVMECMSLCVATPSLNDPGPPPKSKLPALPKTLDQQLPPSEPLLMADDDSTIANDTYSPSELKSNSSWRNTHSTAITQYTSNEPLPIQKFSNPASRSSRAASPASRGQDTAGCDSPTLPPVENVPDLPAKIPEISKSLNFPIPPPSEPTSPTLEEFGRKLSQRRKSPKYLRRPEDQSQIATLQRELMLLRNDLHFERYLKLQHLSHIGQLQRKHIKEATVEAETQNLINANKALRAKLEKANKLMEQLKKQQGDSRARSKKWEGDLSTKVKFLREEQKSWVTEEEALRHELTKYQRDCEELRTIVVQRESAKVRAEQHLQSLQADLSELDALRHEVDSLQSRLREYELRELDFEQAKEDKELLRADLDSALLKLNHKDAELERTRKVYEHKLLDMERRLNHVKTYEMQAADGRLPDSVQAMLDSALAASNSRIDRMRKAHTKLLNRYNDLQARYYELGGDFDHPTGQPQMQQEPDRTVHAFDRRPSHMSGGGGSGPLMFNSNYRRPHAFSDPIQDEEEYMAESPTGYHSSGMSSGPNSFPNRPTRYESLTNRQNPAFSDNEYMNDMPAQQHEYGGPLHEANTGSFRALQHQHQHQLAPSTSHNAPSETVHSSNRSAFSIESGSSNSKSEKNKEKITPKSDVRVYGRGECSQATSLLLNSRVSLSLFLFPSYISALLRIPRGPSRSPLACMSSAPPSISHGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P541</accession>
    <name>A0A6A6P541_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_339838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P541"/>
    <dbReference type="OrthoDB" id="3357002at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="40281" checksum="6C503314D3ED4188" modified="2020-06-17" version="1">MSSSGPPQQQSGPPYLPTTWTIGGIPDKSEDIPATSVFLALYVLGAATHMAIFQINRRRGHKFIFSVLMFGFCMARIVTCSLRLANLEHPDNISLAIAAAIFVQAGVLLVFIINLLFAQRLVRAQHPHFGWSMGFRVVMIALYVLVVLTLAMVITATVQSFYTLSTNTRRIDRDIQLYAGSYFFFVAVLPIPMVLLSLAVPRRSGTDKFGHGRFRTKIFVLLTASTLLAFGAGWKLGSNAMDPVQRRGNPVPWYYTKAPFYIVNFTVEVLVIALYALLRIDLRFHIPDGARGPGAYSSGKRDTALSTDGEAGGAPKDVGDLRRPSRVYTEEDAYNFDYDDEARSPVESTMNKTLSHDEGKKEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5F7</accession>
    <name>A0A6A6P5F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="11">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_340221</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="11"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000041">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.280:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="13">
        <location>
            <begin position="364"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="13"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="710"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1316"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1316"/>
            <end position="1335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2459240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1395" mass="156565" checksum="24E7640CEA245A93" modified="2020-06-17" version="1">MLLYGAQRAARFSPRRLSSSPLQPTQIIRPRAARTTRRASATSAAPPQSLEPRRQRSVRAGLSSQARARSLATAADSISSHRFSETLPFAVDPSWVTPPKNEPSPGMTRLRPYQPPIVVHDSVAMPPPKVTMAKDLGAHPGEVYQNLHACIRVGRLQRAAALVRRLGDYYNSHAPELLDAHNSYLEACVEALPKKHADASWSSIQRWFEVEMRGKGVQPDGKTLSLMIKGVFAVQEEGSRRDRAIRRYLHLANEAGNHIYEEMMASGIYSDEEWDVLVRIEADKFLSPPPREPILSEVQEEASAVPIATMPATAKPDLRPVHLKGMGMTELKHALSTLSDANAIPFPHDVEETQGGRDKYYAYMQQRRLEEDVVDAAIERWREEFKSRQRMELTAPLASSSLGQTMWAWQSTLVPLITKEQEACRKALETPGQRQDEPSRLEYGPFFERLNPEKVAALTLITTINLLGTQGVSEGVKLNVLSSRLGNALELEGSADDGMNRVAASQKKSLKSRQRMALLQKLSRQTTQSQRQRAHRDSERFFREFEKDDWATGAKIKLAAWLISRLIDTATINVTRPNRRTGIPVTANLPAFRHGYQYHLGKRVGLLIPNEAVVEKLTKEPDRGVLGSRLPMVVEPKPWTNERDGGYLRYTTPLVRFKPGDELSKMYISAAIRKGDMDQVLAGLNVLGRTPWRVNRDVFDVVAQAWNTGEGIGSIAPEDPQQELPPEPGRDASPREKFQWHETVRQVENERSGLHSQRCFQNFQLEIARAYLDKVFYYPHSLDFRGRAYPVPPIFNHMGADLSRGLLMFGRGKELGTTGLFWVKVHLANVFGYDKASLKEREVFAMEHIQDVYDSATNPLNGRRWWLSAEDPWQCLATCFELKAALDAPDPTRYVSHLPVHQDGTCNGLQHYAALGGDEIGASQVNLTPGDRPADIYTGVSEIVKAEVAKDAAEGNPFAKVMDGKVTRKVVKQTVMTNVYGVTFIGARDQVLKQLEAIFPHFESTSQVSLKKMAAYIAKKIFKALSEMFTGAHDIQHWLGECGDRICRSLTPEQIEVLRHNAQGKEIKSKYKKFNKRTALEICTNFRSSIIWTTPLKMPVVQPYRITKAREIATTVQSINVSRPHVSDAVDRRKQLQAFPPNFIHSLDATHMLLSALECAEKELTFAAVHDSFWTHACDVPAMSNVLRDAFVRMHSEDIVGRLAEEFNARYKGSMYLASVSRHSDLGERIVRARASLARERSVKLKKVPKVGRYGDVEELLVEQERFRLLHSDDPVERERGAAMVTPCSVFEAAGSEDALESETNATILGEVPASIDKDSQRGGTYRKNEGDKYAPDTLDDAETEDAPAYVRKAASSVKGVTEKVYIWLPISFPPIPKKGSFEVQKLKESRYFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5H5</accession>
    <name>A0A6A6P5H5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_199379</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="242910at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13980">
        <property type="entry name" value="STKc_Vps15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000497">
        <property type="entry name" value="Phosphoinositide 3-kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000342">
        <property type="entry name" value="Serine/threonine-protein kinase VPS15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="25"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="438"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1133"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="906"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1521"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="979"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1569"/>
            <end position="1581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1631" mass="179808" checksum="8B943B7D7BD5BFC2" modified="2020-06-17" version="1">MGQGYSLTTLPAGSAGIDVPELADLSYEKSLGNARFMKSIRARTKNGLAVAKVVMKPYPSMKLDPYVTALVHEGKALSDVPNALGHHRIVETSTNGYLVRQYIHSSLYDRMSTRPFLEDIEKKWLSFQLLCAVRDSHARNVYHGDIKTENCLVTSWNWLYLTDFSSSFKPTYLPEDNPADFSFYFDMSGRRTCYLAPERFLSARDSAEGHDGVNWAMDIFSVGCVIAELFLESPIFSLSQLFKYRKGEYEPQHTHLSKIEDVDIRELASHMIQLNPEKRYSADEYLTFWRRKAFPDYFYGFLHQYMYLVTDPSSGNTALSNEEENMGEADERIDRIHYDFDKISYFLGYENEPDKAKRGSSSLQSSNDLYPLHIDIPNNQHQVVSKASRNSDDGTLIFLTLVVASMRSTARAQARIRACELLLAFSERLTDEAKLDRVLPYVMSLLNDKADLVKISAIRTLTQLLALVSVVSPINAYIFPEFILPRLQPFVPGSSSKPNALVRATYASSLAMLATTASRFLDMMQALRADGSLPSTDPEAEDGTISRSIYQTLFDVAREDLVLSFESQTKALLTDSDSSVRRAFLGSVSSLCVFFGSAKANDVILSHLNTYLNDRDWMLKCAFFETIVGVATYVGGASLEEFILPLMVQALTDPEDFVVERVLRSFAAMANLGLFQRSTTWELIDVVGRFTMHPNIWIRESAAHFICASTTYLSVADCHSIIIPLIAPYLKVFPSNFSEVKLLDCLKKPLPRLVFEMAMTWATKAEKGLFWKPAQRQRTFSVGEAEDATPTLSARDLGPKALTRIPKNEEDEQWISRLRNAGMGPDDEFKLLAMREYVWRVAQRRSKDPVDTSSSRFNSIVPMKDLGIAPQTIFFDNDPKFLDNTKNGAGTPTNEERRPHTIADALLDASTTVDDPISRRKRSHINTHLGKIGRTVSVDGRLGETQSNPPVSAIEVQGSGPPDGKAQRPADQTTGLRKRGADSSLERLSAESIDTKVDGHAHGLRHKGSAISLLNAGEGMNKASAETGTTSANAFGKIDAANARRTQPSPLSTALPLPAPKREKAKFQAAHSYQGNDPTVLRLLDNLYLENYPLDELDFGPLVTPITRRRPISRPGAPASMPWRPEGTLVAVLGEHKAAVTRIALAPDHSFFLTGSDDGTVKVWDSARLEKNVNHRARLTHRHSEGVKITALTFLEDTYCFASMGSDGSVCVVKVDYTPLPPPGSGSGAATTGRYGKLRVLRSHQLDVDEHAVWSEHFKSETQSILLLATNTCRLVAIDLRDMSLIYTLQNPNHHGVPTCFCVDRKRHWVLLGTAHGVMDLWDIRFRLRLKGWRFSAAAPIHRIMLQPLRSRRNRVIVAGGSGQADFTVWDLEKVACKEAYRIVGNPTVYGNPSSLSSSSPYRLLDIDEERAGSMLSRFATSLPSPFTAPSASPGPGAAGTSLAPNARSIRAVAGAVHVSDDSTEPRHAFYVSAGPDWKVRFWDLSHPDAGCTISGADIDEPKPIYSVNTTGETIVMTAREGGAVDVAPSTTPSRQQGRVRGGESPAMSPSPTGRAVSRAESNTSARRSGGGGGGSGGSTGGRASRSSIITLQQQNLLKSHMDAITDVAILEYPFGMVISADRSGVVYVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5U4</accession>
    <name>A0A6A6P5U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_420359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5U4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="209" mass="21240" checksum="4B6E4F504BE03C90" modified="2020-06-17" version="1">MCSAPRKHPDEGSAVYIKPQTRIPAAIPGLDSRELQGRGSAQFLEASEAGGTASFPAEAAALRGVVVMAGRSSPELAPAARPVGASSAGPRWSSPPIPREPCLGGARGSPGAPRRGSSVPREQGSLALETRRTNILGPGQGQPGHRATGGSGAPIVCTCYYCIRRSTQSAAARPFLAATRAPSAAQGTFRRRLVVVKQPAGPLGSTAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5V5</accession>
    <name>A0A6A6P5V5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_273939</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5V5"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000007">
        <property type="entry name" value="Interferon-stimulated exonuclease gene 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="10">
        <location>
            <begin position="2"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="18785" checksum="578269F83EF98605" modified="2020-06-17" version="1" fragment="single">GKFVALDCEMVGVGPDPDADSQLARVSLVNYHGAVLYDAFVSPVQPVTDYRTRFSGVTAELLARFGRPFAAVQADVAALLDGRVLVGHALRNDLAALMLGHPKRDLRDTARLPKFRERAGGRTPKLQKLAWEVLGVEIQGGEHSSVEDARAAMLLFRREKAAFEEEVVKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7W9</accession>
    <name>A0A6A6P7W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_419731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7W9"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025482188" description="LysM domain-containing protein" evidence="5">
        <location>
            <begin position="29"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="226"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="277"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="368"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="583"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="670"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="637"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="639"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="722" mass="76693" checksum="D7560F10012F2969" modified="2020-06-17" version="1">MSLVSLRRSLSVTHLTLLLVTLAGYSSAQQFPNSSFNADYPGLSSACATAVNPSLECDDVLGSMSIDLVYLDDDDLEALCTTTCEQSLLDAQASIQSACAADTDVIVDLGVAYPASYVLDHFIYAYRSTCRTDSSTGEYCQTLFQEWMNETGLSRDEECSDCMLGVSQIQLGSPFGYSEEYAQNFSSTTESCGKTGYSYSTTSTYGLNNTATPTPTGSPTSPDCPDTYTIAGGDSCTSISLSHNVSTFSLLYWNGLTSGCRDFPSEGTTICLPSPCDIYTVEENNTCFGIIANYAPDYSIRQLQSWNMNINALCTNLDQMVGTQICISPPEDIADSMPTNTNPVVTSFTSPVPAPTNVADGTNPRCGRWYTVQEGDQCGLVSAQFGIPLDDFYFLNPEINANCTNLLLGEAYCVAPVGSISTYTNYTGGSPVTGDCTGAFGPSSCYNDMATLTDVPFIEPNATWGPIATGSSSSWVSPTPEPTAPGTISGCKLYAEYEEASNADIEASINTCRSVASFYGSTVELLLEWNPSLSEDDCNLEKGSSYCVRKDEIVSTTTSEAGSSPTGVTPPGPTQDGIVENCNKYVMQEDGVYCADMAADAGISLDQLYEWNPALGGDCSGLWPDYAYCVGVSDDDDGGSTPTTTATQSPSPTGVAPPGPTQSGIPDNCDEYVMQEDGVYCADMAQNAGISLDELYDWNPALGRDCSGLWPDYAYCVGVSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8M3</accession>
    <name>A0A6A6P8M3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_377401</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8M3"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032108">
        <property type="entry name" value="CLIP1_ZNF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF83">
        <property type="entry name" value="TIP ELONGATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16641">
        <property type="entry name" value="CLIP1_ZNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="9">
        <location>
            <begin position="105"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="161"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="613"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="770"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="569"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="660"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="812"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="851"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="908" mass="95012" checksum="7D3DE9AB2FBF3370" modified="2020-06-17" version="1">MGSHQQQPQQPQQLLQTPRRLPASRPSLAHSSINTASTPSLSLAARTDLARKASLSALTANGSQQLPQPTSPVPPMPDGAGAPAVEVGDTVDVPGSMYGVVKFVGNVKGKKGTFAGVELAREFAARGKNDGDVDGTRYFTTSVPGAGIFLPVHRASKRMTPTVNADTFPPTPTTPSFSASAYGLNGTSHGSPETPAVPPKFSQSVGPGARAPSPVLKPKPRGSLPRPESPFPQFSKSLMGPPRYTGASSTTSSPGPTRSAIAKPPPRTPSARPYSRSGSRLGDYESIAEDPDTTPVGASRTSGSSSTSGFGMRGRPGSGPAEEEIQRLQKRLEERDRQLREQAASLTEMENSLAELQTLIPSDTTHQRGMSLSGDDMTNDAAQLRALLREKNEKIAALTAEFDAHRADFRSTIDTLEMASTETVRVYERRTEDLLAEIKELQDRGDDVESVARQLKQLEELVQELEEGLEDARRGEAEARGEVEFLRGEVERGRSELRREREKAAAALKKAGQAIDGGGSGGSSFREVEQRDDEIRGLKAIIHSLSSGPDLAVSPGLGERGASPGLGASAAMAEELERVKATMDRLEREKDELRGLVERKAFREEELEREIDLLRRGGGGSGTSPSTTMAPPRRAGAVTPNSNNNIGAPQHAGDHPRDSVISNALSDRTATQADTGAANASSKRSSGRDSRGTVISWRGGQSPKAARGHHAHHHHHVAPTPLEPMIELDAQSATTSTTTTTGGSGALWCEMCETAGHDILSCANLMGGGGGGGGGGAQPDAAAKTSNDALVNGSPARAGAGPHQLRRKESSIADAAAAAKSPSADAHPAPLFQPRRVGSSGPAGPAPSASPPSAVAAPAPAPASAMPSPYEGGLVPAKGEQVADPNKWCALCERDGHDATMCPFEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8U7</accession>
    <name>A0A6A6P8U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative endo-exoxylanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_383929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8U7"/>
    <dbReference type="OrthoDB" id="2012278at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039514">
        <property type="entry name" value="6GAL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14587">
        <property type="entry name" value="Glyco_hydr_30_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025395855" evidence="4">
        <location>
            <begin position="18"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Endo-beta-1,6-galactanase-like" evidence="5">
        <location>
            <begin position="18"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="6">
        <location>
            <begin position="368"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="458" mass="49195" checksum="ED74A2BC7B506A1E" modified="2020-06-17" version="1">MRLIGTFGAVLAPLTSTQITVELSQTYQTMDGFGFSEAFQRSNQLHELPEDSRQYALDLLFNTTSGAGMTILRNGIGSSPDSRSDWMATIAPQNPGGPNAELQYVWDGDDNSQVWLSKKALEYGVTTIYANAWSAPGYMKTNGNDANGGSLCGVSGAYCQSGDWRQSYADYLVQYIKFYQQEGIQITHVGFLNEPELSTSYASMLSSGTQAADFIKVLSPTLEAAGLSETVGINCCDAEGWNHQGQMTNEIRNAGAEDLLSVVTSHSYTSQPSNPINTPHRVWQTEYADLQGAWDENWYGWGGAGEGMTWANRIFDAITGANASGYLYWIGVQGGDTNSKLIRISNGSVSPSKRLWAFAQFSRFIRPGAVRVGISGGGWNMKTSAFLNLDGSVSVQVINSGGATSLSIKVGDMTGSTVTAWLTDNSHDLDQIDAEIGSDGTVSGNVPGQSMVTFVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9J7</accession>
    <name>A0A6A6P9J7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative calcineurin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_335869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RCAN family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9J7"/>
    <dbReference type="OrthoDB" id="17212at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008597">
        <property type="term" value="F:calcium-dependent protein serine/threonine phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12434">
        <property type="entry name" value="RRM_RCAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000503">
        <property type="entry name" value="Calcineurin binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006931">
        <property type="entry name" value="Calcipressin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300">
        <property type="entry name" value="CALCIPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300:SF14">
        <property type="entry name" value="PROTEIN SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04847">
        <property type="entry name" value="Calcipressin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="258" mass="28208" checksum="C007487DAE04D116" modified="2020-06-17" version="1">MATESSHRPSCSLSRGSRSPGLSLDLSDVPALIQPSPPSNTLLITNLRDPSIFHPANLSSLRSIIDETATIYAWSPLKSFRRIIVSFYTVEAAIAIRQKLDGESIMGERVRVYFGEPTPTEPVDQHLQAPKSDKLFFISPPPSPPHGWEMRNEEPPNKEVHAEDLSHALARLQAHAHPESPADDSGDVAMPDVGRQRSGSATILYHPGEHGHSPDLPAIAVEDTSDGLEQDGLADSPLEEQKSFHHTARPPVELMHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K7</accession>
    <name>A0A6A6P9K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_280746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K7"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000925">
        <property type="entry name" value="Zinc finger protein 668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="205"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="447" mass="48901" checksum="9710F205C585948B" modified="2020-06-17" version="1">MQHDLQSQHYGQPSYLNGRIKSENGSERGVSPHASEQSSRYSSQPPSIPPYPPMSSNMSSDMRYPSPSQMQAPVPLLNNHYLPNPPDPHYQPQVQQAEQPAQQPNGRANGGESGPPKAFACSTCGKGFARRSDLARHERIHSGIRPHVCDYPGCGKQFIQRSALTVHQRVHTGEKPHMCERCGKPFSDSSSLARHRRIHSGKRPYKCPYADCQKTFTRRTTLTRHQNHHTGTVEEAAAATAAALASRASVPSRSTRSDVDEYSEVASPLPTPSPNERPVSLSPSAGMPVVQSMHRQASEYSYMSGMNVPPHLRSELQQPSPRSSPSLTSQSYTSAGAQPRPSLTSHPTNYGPPSVLEPPTNTNHGTPGSTAGSPHMGSVGWQSPSQQSMPSPNPADGYVYPEPHYGAAAPNMYYHNSAMRRPQSAEPDQYDPRQQRMPGDMWAPPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAL2</accession>
    <name>A0A6A6PAL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_403157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAL2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="19875" checksum="DF55D800BD5994C6" modified="2020-06-17" version="1">MYVGIILACRLSAVKGNFARTRNDSNGTDPPGIPIPPLRPSDPGSREQISTGAYEASTPAASSRHAGTTTPALTARVWLRTALHLDSSTTVCGSAPTVAAPASRRRFSLTTGVTRILKGAHGAVADGNYVLVPGGRSRRMETLSVDSSSRRCDAAAGTTALEIPLSFENDESDPATWEETRGRPWPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB19</accession>
    <name>A0A6A6PB19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_140326</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB19"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="132"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="473" mass="52006" checksum="886ADFACFB07F047" modified="2020-06-17" version="1">MVSAKPSRGVGPDGIAYPRSSGVKVIVIGLGYSGVVTAIECHRKGHDVVVYEQAPELTELGDIIGITANAAQIIAKWGNGKVHSQIEPLLCTWAANNIRKHDTGEIIFPQPMDGYAAGSGYTGPRGPMAMIFANHCRELGIPINLGKRVTEYFETENEAGIVVDGQRISADCVIACDGVKSAARPFITGINDKPHHTGYAAYRAWFSSEEARKNPKLSWLFEGEYDKMETYIGPDQHCIIGTCSHQNGVVWTMTHKDIYDTASESWAFPGKHEDVLNYTKGWHSRIHDVVNATPASQLVDYKLLWRDALPSWVSRHGRMIVLGDSAHPFLPTSAQGAGQAIEDGATVAICLELAGKGNTPLGLRTCEKLRYARATLAQKIGFETRDVWHKTDWELAAKNPQSVSMPLPNWLFGHDPQKYAYDDFDAAAQAIKNGTTYVPTNLPPPGERHRVNDFKPQDASPWLRGEIVPRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB24</accession>
    <name>A0A6A6PB24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_279851</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB24"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="365" mass="41983" checksum="AB6EBF02562F8C27" modified="2020-06-17" version="1">MTDDGADPELLELLRQSLGLGSTGADAPPETYVLQSAKFIYDNSVDVAIDMYGTRAAAECIWSAMSQRGYSTKTWSEHELHPKTRDEAAVNFIFTMDLLNFSFWSMRSPEERFAVAYRDKKWTGYWSLVAALQRAVGEEIPICTPSFWADSEACTDQSLRHVFRSATEEEMPLLQERMECLREAGHVLEENFDGSIINLVKEGRGSAARLVNLLAEYFPCFRDETSFEGRKVRFLKRAQIFIADLWAAFEGKSYGSFEDIDKITMFADYRVPQMLHSIGCMSYSPPLEGHIFRERKLESGHSWEIQLRGCSIWAVELIRREISRSHPDAYVNAILIDFFLYDAMKAIEAKKEEKIPHHRTRSIWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB30</accession>
    <name>A0A6A6PB30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_139907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB30"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="227" mass="24307" checksum="A6F4AD0FABA1B20A" modified="2020-06-17" version="1">MENVGDGVGLNSVAPIECFNWIHSSPAEFVHDAEESVECAQVSFPEARPPRPSSLRTYVSPSQSPLGALATTQERQPSNLSPRRSNAPLSLSADGSVTSPSSLATPPARPIPPSLPRTPRRRFCFSHVRHPTSAPLFMRPRGRRIVSPRTPSNAPRSARAITLAPRARNMRSTYICTSTAPRPRPAGVDSAPRPGGPRALLAAIREAQRRPLRAAGAAVPDASLQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB59</accession>
    <name>A0A6A6PB59_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_279045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB59"/>
    <dbReference type="OrthoDB" id="5397827at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="293" mass="33538" checksum="237CD782CE8D56DD" modified="2020-06-17" version="1">MASWRSIPRYLLPSRAQLPQTTLPRRRIGLGPSAAASLAHTTSIAPFLGRRCASSSVKRSPQGQIVLEQPDKFRPPSHPARKPRRSTRWTYGPELSEKEKQAQGRRQYPNMMPPEGSFLYWFLLNRKLHAFITISVLVSLAFFTLLSDFLRNLSPSLRPLLPDSSAFLNHPFASFSTTWQIYREHISQQTAAVEERRQRFAADTEKRRAFRRAHGIDEGWVGQFGWFDSDPDAEERRQRAMRRARGEDPDAVPSAPAAEEAKAEVREEVEQLPPRRGEPGGKPKPKKWFGIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBD3</accession>
    <name>A0A6A6PBD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_278510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBD3"/>
    <dbReference type="OrthoDB" id="2349272at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="19709" checksum="56273913404AEAF9" modified="2020-06-17" version="1">MDAIRRVDTPITAAVIQQIAPSTASCSGAAFPDECATADVAATALGASFTTYDISSAAEQTALLALVLFESGNLQYDRNHWPGVPGQGTRNMQSPAYNLQYATALFPGARAQAAQAQGPAAVLYLLLGDQESFGSAAWFLSTQCGQDVRAALQAGTEQGFAAYLTQCVGTTATEGRLQGWRAARQVLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBJ2</accession>
    <name>A0A6A6PBJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquinone biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_257306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBJ2"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025571439" evidence="1">
        <location>
            <begin position="20"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="120"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="58869" checksum="580C14F808CC0CF7" modified="2020-06-17" version="1" fragment="single">GRGRGLPVVVVLVAAGVLGVGVGVGAADEARHAWTAVRRTGRVVGTLGVCVNDYRKTLPLRDEVPADEYAALLSACHQRCADRTLAALEANGSVFIKLGQHLSSLNYLLPSEWCDTFIPLQDRCPVSSYESIAAMVEADTGRPLTDMFSSFEEAPIGAASLAQVHRAVERGTGAAVAVKVQHPALAEWAPLDLALTSFTFAALKRVFPDYDLTWLAEELESSLPVELDFEREAANAERARAHFAAAMPDGPLVIPQVHWARPRILVMEYVAGRRVDDLAYLDGEGIDRDEVSAALARIFNEMIFGEGAPLHCDPHGGNIAIRRRRERPDDDGGGGGGTNFDVILYDHGLYRDIPVDLRRAYARLWLAVLEADEGAMRACAREVAGVTDEQFPLFASAITGRDYVEGGRGLVEQPRTSEEKEVMGRALAGGEGVLQQLVELLGRVPRVMLLILKTNDLTRSLDDSLQTRQGPARSFLILARYAARCVLAERVEALRAASPAGAAWWPPAVLLGLVRAWTAYAGVVARLQLFEAWVAARRWLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBZ5</accession>
    <name>A0A6A6PBZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_83702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBZ5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="23308" checksum="1990144CE81511ED" modified="2020-06-17" version="1">MSFEGQPVRGANTPAVRGTERTISRGFPPSNLILTPMGDGPWTSSKTKTRAKSPASHRGARRASRRAAVERGPSKGPAGRFRRHQVWSGATITVICNPLFWRGASHASLLPVADLAAMLGDAEWKIREESEKYQKSLATVGCQPPERQPGRSNMTSPRRWVGRGCGSWHPESPGSKPNLGPWHGLPSRNRMVLLKRPVPASTLTAPLAVTRRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCL0</accession>
    <name>A0A6A6PCL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6536 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_278427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCL0"/>
    <dbReference type="OrthoDB" id="5429634at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046623">
        <property type="entry name" value="DUF6536"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35395:SF1">
        <property type="entry name" value="DUF6536 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20163">
        <property type="entry name" value="DUF6536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6536" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="576" mass="62262" checksum="706749492B64EDA6" modified="2020-06-17" version="1">MQLAVAPTRHDLDEAHSRKRWLDIGVPSIRNLEWVSIGRRVAWALLFLSAMPLHLFYNASFFFGRTTTEYLVAEMGESFLDTGPSTALTNVSETRPGVLDAFENIVLHAPSWDRFTPEECAAIYSKPLMTGHRTLVLITEEERVQRLPGLWSIVGSGNWMCDDDNDDPDPIDPRGASCHPTKARFGDRDGAELAPGTTLFCLAEPFAEDCKLEVSTSLLVAVAVCNALQVFGTLLLFFVLEGPSPLLVTVGDAAASFLARGDIFTKGLCAYDHWLLRWRWPAIDERLPIPWTTRTLRRHAGVSKRWLVMACAALAAAIILAIISLGLALAADARRGTISAAMSYGAFLAKNRVALISLARRTVPQVALLVNLPQLAFSALYLLYNAVLSGFLQAAEWNRFARARHPLRLSARPGGKQRATRWLSLPPRYGAPLALLGALTHWLISQTIFLADVSSLDFSGRDSVDHNTLAAGYSSLCVLLVLIFVLVAAVALAAVGLRPLTGDMTVAGSCSAAIAAACQNAGETEFGAPVGGGAEDGFWTLPLQWGSLGLEDPDGVGHLAFSSMAVMPPLDGALYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCN9</accession>
    <name>A0A6A6PCN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_278736</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCN9"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 13" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="517" mass="55847" checksum="CA1C96BDA7CC64E1" modified="2020-06-17" version="1">MPPRTVSRESAEDFLSFVNASPTPFHAVKSAKQRLEAAGFEPIKERDSWASTIKPNGKYYLTRNASSIIAFAVGGAWNPGNPIAMIGAHTDSPCLRIKPVSKRSSDGFLEVGVETYGGGLWHTWFDRDLSIAGRAMVRDRRNGGAIVQKLVKIERPILRVPTLAIHLERQETFAFNKEEQLFPIAGLVAAELNRQGRGLAEPLEGGRPGSPSSGDNGSFEPLKTMRERHHAYVVELIAREAGARPEDVLDFEMVLYDTQKAAIGGLNDELIFSARLDNLMMSFCGLQGLIESLGSSAGGAKLDRDPSIRLLALFDHEEIGSTTAQGADSNLLPAVLRRLCTLADADADDAAYADPASPTAYEQSLARSFLVSADMAHSVHPNYPRKYEAAHRPEMNRGAVIKINANARYATNAVGMALLQEVARRARAPATPACGADTAAGVPLQLFVVRNDSSCGSTIGPMLSAALGARTLDLGNAQLSMHSVRETGGVWDVEHAVRLFESFWGHYGELEGMVVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCV2</accession>
    <name>A0A6A6PCV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCV2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="618" mass="64738" checksum="78851A79DE88C5D3" modified="2020-06-17" version="1">MSSFQSAELFPIWDLGRSAACRAACPIKPARGAFCVLKGISPPADALPAPGLAPSLSAWSPPPQFPSTRPSAGDQGAAPRISGARLFRTRTLPLLAVHGGSGYERLDALHHQGPTAAAVLPWTTVGAANPRWEALRGDAREHPFAVTRLLVEYGNVLAGRLVAGYWEAGMWAAVEGEQESGGGHGGGAAATTRGLDPEVDDGWDGVPAEAYDQAYALFTTSPTWQAWAAVVHRLCRSLGVTPTTPKPELDTWDLEADLEKLNGVLALARKRRAGRAAQPAKQRPKQQQQNQPQKSKGRHRGKNKGTAQPASAAAWPKAPAGRPPAPDKQPAYEPDTANPPAPELAFPPTLPDLAEWAEQAGERARDQRAQKPSAAAATAPAEAPASTRTPPGPAAAPTAAPTTDDRSDAGRALQRQLVDRTRGLNARGPQQQQAPTAAPAPHARTRTRTQRLPPHRRVLEATSEADVRGQAEATRRGIPAQTGAGLQTAGREAGAAPAGGEEEVGAWRAFAEGEAARAEQEQEAAARGPGRRGGGGAREAGDGGREEGGRDGDGDEDDGDEDDGDEDDGDDELVFTGREPRPASDWDTSWFEKTFGGGASAAAAPGGGRKGKGRHEFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCV7</accession>
    <name>A0A6A6PCV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_332584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCV7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="25375" checksum="21E838914535A6B4" modified="2020-06-17" version="1">MYAGSRCTPRRFAWSVHPLPFGAKRPSGNRQARKSRRVESLPCPEPWLRPLGPVISLSSPVSLPPGPRHGEPQSAKGLFLVALRFGRPKAAAKARFRRDCFVREAIRTTRFDCGLKKRPPSFVPGLLLLFSPSLPSSRDAVAAELLLSCICNLVRLSVLPPVALQECRWVVQADSGVCVLQVDRYVSICGRKLTRELLLYVSPDFVAANVRQRRCVLAERSFFVSLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCZ4</accession>
    <name>A0A6A6PCZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Target of rapamycin complex subunit LST8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_368835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCZ4"/>
    <dbReference type="OrthoDB" id="400at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098588">
        <property type="term" value="C:bounding membrane of organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000339">
        <property type="entry name" value="WD-repeat protein pop3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="71"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="112"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="265"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="325" mass="35821" checksum="6123A3537C74F11F" modified="2020-06-17" version="1">MSVILCTAGYDHTIRFWEALSGICSRTIPHPDSQVNRLCISPDKRFLAAAGHHTVKLYDIKSTNPNAVLTFDGHTNNITGVAFHIEGKWMVTSSEDGTVRIWDTRTGSVQRNYSHGMPVNDVVIHPNQGELISCDRGGNVRVWDLGENKCSHQLIPEDDISVSSVTVATDGSLLCAGNNAGNVYVWRMIQNRDLTSLVPVCKFVAHNTYITRVLLSPDVRHLATCSADHTARIWSVDPSAPHNTVGAEHLPPARDPDAFPLETTLTGHQRWVWDCAFSADSAYLVTACSDHYARLWELSSQSIIRQYNGHHRGAVCVALNDTALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCZ6</accession>
    <name>A0A6A6PCZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCZ6"/>
    <dbReference type="OrthoDB" id="2129362at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="77372" checksum="16B93C2FC2073041" modified="2020-06-17" version="1">MPGYSSEETMQDGFFPVTYLHPNDEQFEKKCLARTKAGLNGGIAGILALKAEQSGQSTKTGRADFLGGSLPKTGGGNHPGNHSRNAGGGFRGGQRGGGAGGQRGGGAPRGGAQRGGYRGGHRGGFNNGGNRGGSNNGGFNKGSPNNGSPNNGNSNNNGPVQAELPSAEAFRNPEKAARQVTEADAAAKRANKWGTKEEFRAPIVLPPPTDASCVSSAWDPENCEYEEHMKRAADMDWDCKQLADEDGNWMPPPIDWDYRSKFRNYGLSETINEWRNAASVSVEELKLDDKIFRGEAAPALAPKSWIPEQIEGYPAEKFWDFHLKGALHCYYDGDTPWWRTYYNPKSVFLKVEHPPCMLNVMDEEYYKAKGDIGSMDNGSKYLKFRAALREKIKRSRQVKEMTEKSQHLKIRKDYAANTTEPLPELWGPNANVYFRPVMPTDVDGIAEIWNHYINDTPYSPETVAITPSTVGARIADVIEAELPWIVAVKLNDKDEKTSSGSSPNNTPPHLRRRRNVRVHEKIVAFGFFDDHQSRESMYSRVVEMEVYTAPDFCNLGIGRCIVDKLCHISHTFYHPNSGYDWRLGREPNSIVPIAQEGRFEAGGRRRIDRVIVNVTTVHDQAVETERVLWLQAMLRRFGFIHSHTIEGFGAKFGERTDLSVFIRHNTDGRERDGPSLAERLVAADKFAEPWRFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDL6</accession>
    <name>A0A6A6PDL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_412908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDL6"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF4">
        <property type="entry name" value="CYTOCHROME P450 98A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="549" mass="62043" checksum="3ECD6DB61F38BFE4" modified="2020-06-17" version="1">MSTDNVLSPIVAKLAAVQIPPSLLKNAVVALSGLTAIIVIGIVADYVRMLRLRRTLPPGPFPLPVVGNHLQIPKSKPWIAFEKWSKHYNDPLLTIWLGRRPIIVANDAWSASEMMEKKANIYSSRPRIVIMGDMFNATNYNQVVLTYGDRWRLHRRLMHTVVGSQAVRSWRDIQSAESKIMIRDLLDEPEDYVFHIERYACSVVSIIGWGRRINRKNDYVAQQALAMMNNAVDVVIPGAYWMESIPELTKLPKWLYKLPSLIWEQSNLMLKYFYALSLEGSKAHEKNFSARLIDEQEASGLTNEEVATLTGNLIGGGVDTTSSTILSFILAMCVFPEVQKKAQAEIDAVVGQDRAPVWEDEDSLPYVQAIVKETLRWRTVTILGGIPHAPIKDDIFRGYHIPAGTNITGNLWAIHRHPREFPDPDEFRPERYVDGLQFDYPNTRGHNAFGWGRRQCSGQPLAEQGLFLTLASMLWAYNIQPGLDKDGKQAKLDIFAYTDGENMRPVPFPARYTPRSKKIESIVRSEAAQAREQLSVFDGETKLTIADVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDW4</accession>
    <name>A0A6A6PDW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_296929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDW4"/>
    <dbReference type="OrthoDB" id="3621151at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="74" mass="8971" checksum="FA78ED64D8BB28E7" modified="2020-06-17" version="1">MCSYTYSWYYCNHDYYIWSNTIEVCHNRLLSGYSYDAWSIDMCKNMSVKCGGFSHYYCRDCSEDVSLEYKLQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE70</accession>
    <name>A0A6A6PE70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE70"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="72" mass="8052" checksum="CB30CA8B8DF68AF2" modified="2020-06-17" version="1">MGVLGVSLGGLGFGFWVVFCGREGLRVLEGFFCVREGISFAVGPALGLVAFCSFWTLWERWLVRFVFVWLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE84</accession>
    <name>A0A6A6PE84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_368386</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 15">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE84"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000008">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="17">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2462314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="450" mass="50153" checksum="3300C19ECD267B29" modified="2020-06-17" version="1">MREVISLNVGQAGCQIANACWELYCLEHGIQPDGYLTDERKAVEDDHGFSTFFSETGQGKYVPRTIYCDLEPNVIDEVRTGTYRSLFHPEHMITGKEDASNNYARGHYTVGKELIDQVLDKVRRVADSCSGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKSKLEFCVYPAPQVATSVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLGIERPNYENLNRIIAQVVSSITASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVAYAPVVSAAKASHEAFSVQEISMSCFEPNNQMVKCDPRNGKYMATCLLYRGDVVPKDAHAAVATLKTKRTIQFVDWCPTGFKIGICFQPPQCVPNGDLAKVNRAVCMLSNTTAISEAWSALSHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALERDYEEVAADSLGEEEGAEVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEB5</accession>
    <name>A0A6A6PEB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_12109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEB5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="209" mass="22408" checksum="6127A01348B631C5" modified="2020-06-17" version="1" fragment="single">RPPSQIIPPRLHHRARFLLPPLLHRHLSLRPSRLSLSCSELHARAARPGSLAVALSLSCCLSPFPSLLPPARRRSSPATAIRRSHSLLLDRPTACACLCLPASSSCLSPSRPPPPTSQLLSQAGFVPLVFSSTTSLSLYTTTVKSCFLSAVDANPRSSEPAVLKDKLPPNCSPIDALLGLLVSIFCLPSPCSPRNRSIVILPILLRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF55</accession>
    <name>A0A6A6PF55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF55"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="36"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="31163" checksum="D68CA7BCFD372B3F" modified="2020-06-17" version="1">MPTSPDPHSQYITHPSGETSHIIVDDFADPWKPRETVLLQGGFARHAAFFHHWVPALSRQYRVVRRDLRGHGYSSAPARADKPAAYTLDAVLADIVDTLDQLGVDRVHFFGESTSGMLGMILAARHPERVRSLTVCSSPTHLPPATQGFLAMGRASWPEACRALGSRGWGQELAKLGGTMSSADDGYRRWWLEQLSVSSGEGLASYAEFLCTLDARPYLGRIKVPMLILAPTRSAATKIEEQKEVQAQVPGSKLVPIDGAGHEIYVDSAEECQNVYREFLAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL58</accession>
    <name>A0A6A6NL58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_294707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL58"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="11199" checksum="14069C6ED116F982" modified="2020-06-17" version="1" fragment="single">LDRKSYVRILLIHDIGESIIGDIRLYHEKYRCERLAIDFLTTVARDINPSFAEEAKRIWLEFEEGKTEAAKLVRELDKLEYLFQAATYEERSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL86</accession>
    <name>A0A6A6NL86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline-phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_172717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL86"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009141">
        <property type="term" value="P:nucleoside triphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.180:FF:000003">
        <property type="entry name" value="Type I phosphodiesterase/nucleotide pyrophosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="798" mass="87111" checksum="011420432BCD87CE" modified="2020-06-17" version="1">MAPRSVEKDGLLARSSYDADAASLPSTPTSPTSNDDVASAGRPSEELASHDRELLDEEEERERLLTGAQSRSVRQGIQALFARAGPGGAGNDASARERTGSRREKRSARRKEARRKRRGGEEGELMYEMEEGGRRSESEASSERDQHRLGTVMAAKKTRRSRIIRLLLHGSILVLFLILVYLGAVLSKSRKQSYASVFESQTLRSNGSSLFAPTTILISLDGFRADFLARDLTPTLNAFIRAGVSPPYMLPSFPSVTFPNHYTLATGLYPEAHGIVGNSFWDEELAAEFYYTNKSHSMQPHWWADGEPVWVTAENAGVPAAIHMWPGSEAHIAGVEPAHLDRYNGSEVLSRKVDRIMQFLDLPGPDQPGASRTAPRPQLIAAYVPDVDSDGHKYGPNSTEIRTTIANADNMLADVFQGLEARNLTDVVNVVVVSDHGMATTDVSRLLQFEDLLDGDEEAKKVSHIDGWPLYGLRLHEEANLRPMYEALKRKAADDPAFDVYLRDEDMPERYHFSNNERIAPLWIVPKTGWAIVTRDEFDVEEGRRAGAVYHPRGLHGYDHEHPLMRAIFIARGPAFPHTPGSRLDVFQNTQVYNIICDSLGIAPHPNNGTLRLPLRPVGTHFDDAAPPVEIPHDPVVSAGPPSVIPLPPKPEEAPPVVATTPLVNPIRPGATAAAAGTTAAQPSQAEASKAGQEAQETVPAPTQTGSSVSGEPPGGPGAVSSSDQGHDDFAADDDEDDSSSSSDEEEGEEGEEEDEEEEEEEEEPSGWQELWQWVHDKVEAMKDWAHGMNGSNGDGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLD5</accession>
    <name>A0A6A6NLD5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_358831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLD5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="307" mass="35960" checksum="218229262CB1E6F8" modified="2020-06-17" version="1">MQDPHIRDLRTQDSCIQDLRMLYLRMQDLRIQYLRMQDLHIRDLRIQDLFYTRDLRIQNLRMQDLRTRALRNLQVRPTTAVWTWTCSSTRANAPTARLTGQQPPATPCTIYTRATGPPSPPIRQDPLATPRTRRTRATARAKERYPTSIRAWERPWYARSAYLNPRMPAAPRQVRAAIRSWFSRRRRASHASKHASKTLRAARPRGPRWMLPKVHLPARQSSASRSRAPRAPSRLFCCIMCAKVSEGWTAALRHESAVHRSQSFPCSFKDCERSWPWRAYKRRSTLDHHLLDRHGVGQSDLTKKRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLF5</accession>
    <name>A0A6A6NLF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative GTPase activating protein for Arf-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_264899</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLF5"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000026">
        <property type="entry name" value="GTPase activating protein for Arf, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056893">
        <property type="entry name" value="UBA_Nbr1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF7">
        <property type="entry name" value="ACTIVATING PROTEIN FOR ARF, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24932">
        <property type="entry name" value="UBA_NBR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="4">
        <location>
            <begin position="15"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="217"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="325" mass="36068" checksum="9BABEA2E539904B3" modified="2020-06-17" version="1" fragment="single">MVSVLNKRQQARNERALQDLIRSVPGNDRCADCAAKNPAGWASWSLGIFLCMRCAALHRKLGTHISKVKSLSMDTWNNDQVENMRRIGNTESNRKFNPTNVKPAMPIDVDEVDGVMERFIRQKYEQRIFQSPNPRPNVRNNTGSTSSDERPGPPLPPKPTKRFNFGLRTTSSTFPSSKSDERSPPVSPGLGGFGREPSPPRVNKPSRVFGSTVGSSDMDITSKLSSLREMGFPDDKRNAQILRGHNGNLERTVESLIRLGEKSHTPVASNPASTNGITIEKARPPPPAKSATNPFDMLDAQQQQQQPAQPSPPQHQHQQQSYNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLM2</accession>
    <name>A0A6A6NLM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_156799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLM2"/>
    <dbReference type="OrthoDB" id="2398441at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033768">
        <property type="term" value="C:SUMO-targeted ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038886">
        <property type="entry name" value="E3_SLX5/Rfp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28042">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COMPLEX SLX5-SLX8 SUBUNIT SLX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28042:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COMPLEX SLX5-SLX8 SUBUNIT SLX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="498" mass="54763" checksum="4DDF73BC6599962B" modified="2020-06-17" version="1">MDWPRRSSKRSFDDMAHSHRSRSSLDLSSPPPQPHQNQHQHRASSRPGPGSFLQLPDPSRLRPSAGAAAGSSGHRTSTEHRHNPSSITSLLNSHDRTPGADNSGRLQAGGARQFHGDLPFVIDLTAEEGDSPGTVGQWNQSQQQPVQRTPGLPRFSRDIIDLSEDAEMDLAGNRWGAEERGGDLGGGVRASGNLDGNRGDIEPIILGDSGLNSPEVQILSSRPRNLGGNQGRTPFDALRNTVNANNNVHGGDGSRNFADNNDVQVVREHVIRHPNQRGGFDFRTLHGVSYEGGGRRLPRIPGLDENQMRPFGAGHLGEPSRMERGGGRERDGNRRNGRPFRRRVHVGEDASDDDFDGLIGGRGDEAHGFQIPDLNFEMIDINFNWNGNDRDREPPTYEAPEKAPAGFTRSPKEDEYLECPNCGDELNTGDSEVKKQVWVVKACGHVYCGECAKYRSSTWKKKAMDGEVRARWKPFKACVVEGCEKKVSTATSMLQLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMX8</accession>
    <name>A0A6A6NMX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="9">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_149196</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Lipid-anchor</topology>
            <topology evidence="1 9">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMX8"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000032">
        <property type="entry name" value="1,3-beta-glucanosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF5">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025713742" description="1,3-beta-glucanosyltransferase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="333"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="460" mass="49405" checksum="E4C684089736AB86" modified="2020-06-17" version="1">MKGLYTAVAAAAIFPAVLAKPSKTFNKRADTSVTGSLPTVTTKGNAFMAGDDRFYIRGVDYQPGGSSDLADPIADVDGCRRDVAKFQELGINTIRVYTIDNSADHDECMSMLDDAGIYLALDVNTPDYSINRADPHRSYNDVYLQNVFATVDKFVGYSNTLLFFSANEVINDNLTTNCAPYVKATTRDIKQYIHERGYRKVPVGYSAADVDSNRYEMASYMNCGSDDERSDFFAFNDYSWCDPSSFTQSGWDQKVEQYSNYSIPLFLSEFGCTTNTREFNEIASLYSDDMTPVYSGGLVYEYSNEDNGFGLVEITGSSVRELDDFSTLKDALAATEPPSGDGGARLDNPGPASECPAQSDVWDVEENTLPNLPEPAQRYFDDGAGDGPGLDGDGSQTAGTASESDSDIGSGGDSTSEEGEASTSTGAATSVRVPEFSVGVAPLVCAGMVLASSLFGAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN68</accession>
    <name>A0A6A6NN68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_146616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN68"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="18351" checksum="5B68B04F1133A883" modified="2020-06-17" version="1">MKAGRDIELSAAMETAQWTRPDFIPEERGRRAEERVAEVRGGEIRSGGAGRRSGGDGGGGGIQSADPAGRGRPLEGRGATWQVKRSQQGARHPPPRIPLCANPTFCFAPTAIASPPALAAPRLGRPTELARQYRPNQGSDCSCLGVATRLLFSSSAHPQSTRDATAENQKELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNC8</accession>
    <name>A0A6A6NNC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_382456</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNC8"/>
    <dbReference type="OrthoDB" id="415706at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001425">
        <property type="entry name" value="Dynamin GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="37"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="616"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="724"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="814" mass="91988" checksum="B212E413E275B797" modified="2020-06-17" version="1">MAATNLNTSSLDTFRSSEQQNLLDDIDNLRHEGVGEFVFLPQIIVCGEQSSGKSSVLEGISGVPFPQHDTLCTRFPTEVVLRQAATPSAAVMIVPSKDASESDQARLNSFKQSLQRLEDIPDLVKRAKDEMGLTESGKAFSKDILRVEISGPDKPKLTIVDLPGLIQTDSKVQSVADVELITGLVTSYMENPKSVILAVVSAKNEYHNQAILRKARDVDPKGFRTLGLITKPDTLPPGSDSEGVIVDLASNNNIQFRLGWHVVKNRDYNERHWTGEERDRSEEHFFSKGAWTDLPRDMVGIGPLRRRLGKILLEQIQRYLPGLIEDIESNIQDCKNKLLKLGDSRDTPEKQRQFLLKLSQSFQTLCRAASDGSYEHPFFGNPASDGEYYKRLRAVVQNLNMEFSEVMRVRGYHRKIVDNDIRPEVDDGWEGDPSNGEKPLVMSRAGAIEWVRELLVRSRGRELPGSFNPLLVGELFRDQSTRWGRLSQEHVQQIWLASRDFLEKLLFEITDNETSGSLFTHWIDPRINERFDTASQSINRLLADRQKHPITYNHYYTENLQKIREKRQTGTLIESIQKHWGVSSDTISAYRNDLSISKLAEALSRRSQTDMDAFACSELLDSMEAYYKVAMKTFVDNVCIQVVEDVLIGDIWTIFSPPEVGQMHPDLIARIAAESTESQAQRRQLNRKLRILGKGKEICERHSTHSASKTVRARMEAKTALQDDAQTFRSEVSYTSSLRSRVESDSNEGSRGQMAEQKPPSEVGDYLDQGSTSEAPPVAELVEDKEEDGFATKVPHVGLEWRPLGKKSKKRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNI2</accession>
    <name>A0A6A6NNI2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_402361</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNI2"/>
    <dbReference type="OrthoDB" id="26203at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="68"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="398"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="446"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="520"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="584" mass="65502" checksum="99609B7BE3C11EA8" modified="2020-06-17" version="1" fragment="single">MASNNTDNPFGLNPITTPLCDTPFLYESKYDEIGGYVPGRFCVRSPIAKDVQCCLPCPIVDWVYPDDFVTQLRIANWISVASFIICVWLLISYAVLPSKKSHRHYLNVGLIISVIVLLLAWIIPLAARPNMCFNDITPRDMHSSHACAWSGTLLLWGFMSTIIWVLLRSIWMHMRVCWDKMLDHRYMWTSIMVGIVIPAAFVTIQLTVGGVSYRTGPTCLANHKNAFIAFWGWLLAFAGLALLLQVVTIAYCLWVFVLARRVLKGRGRRQSRAADWNNVRRLFQSQWRGFTMTVLCTVQCAYFSIVFLRQDIQVADQSAQSGLDAFNWALCLFRTFGDKEACLPYAEKLLVPREVILAGILMVSLLGLEILILLMRSSLLHAWWDLLRCGHDDANDPLTSLEANPPSSRPTGGLQYNKEQRATSPEKMPKHKALLSSITAINFVPWRNHNRPASPPTLPLTSPRQSQAKATAASAESSISTQQAPPAREPRHHATWTTHAAAMSKRLSWPWHHNKSSSSILALSHTHDHPHTPSSSHRPHCRPPKLVSIPLPRRPSAVSPEPPPKSPARMHSALPDVHAERPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNL8</accession>
    <name>A0A6A6NNL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_374931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNL8"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF24">
        <property type="entry name" value="PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="8">
        <location>
            <begin position="71"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="307"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="557"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="504"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="504"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="630" mass="67665" checksum="64EBEAF619545273" modified="2020-06-17" version="1">MADVWRSIVSALEMVVMFPSMLHGALPPFPSFRSKQEKINRFSEPTISSNAKMRTPDEFLAEVRCLFEAPIQPATMLAMSARLQEQFKPKLENSNICMLPSFNHTLPSGQERGTYLALDVGGSTFRVALVALAGKQAGEAGMRIVHMSNHRIDRAVRGLEGEEFFDWMAGCIRETLATIQKRQTLEDEKEKEVVKTQQHDALSDASDAAIAAAAADAATTDAAVRRADPVPMGLSWSFPVEQTSIRNAMLLEMGKGFRATPGLLGHDLGDLVMQACRRQNLNVRVDAIVNDGSATLLARAYRDAATRMALILGTGTNAAVHLPVTTLSRGKYGARPRSWHARATHVLVNTELSMFGRGVFPTTRWDDALNAQHPQPDFQPLEYMISGRYLGEIARLVLLEAVERAALFGGVVPQGLQEPYALDTAVLAAFESDDSPQLAAAADKLMRDHPLPQDPSPAELRFVKQLATLVSRRAAAFLATAIYALNALRLDAEAAAAAAATITTSAPAARADTPTEPGSASSSSSSSTPPSLASSSSASASDPDPEPPGERPVAGLRRTTVGCNGTVIEKYPGFKGRAQAFLDELRREQQQQGRRRRDGDGGVGPGCVVLLEEAHEAAIFGAAVAACCRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP24</accession>
    <name>A0A6A6NP24_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP24"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="316" mass="33239" checksum="D296E4DE38A76B8D" modified="2020-06-17" version="1">MPGAGQSRRTKTSRGAHAACSMEGPGERPVSLCNKAGVFVEGQEMRGQTKSSVSQLAFRIRLFQGPAGPVEVLLGRAPLGCGSLALSCPAEAPVVHVSRSHAHYKPSQPRATAANLSRQTSQPAIRAAQPSPAQPKIYKAPNDPGAAARFPTLSNRSARLFAGRFGTLPPLPLGLAMWRRCGCGVCKVAGRFPAGFPPARSVELAGSPPSVLAASRLAAWTDDRRLRPFFALCRRSTGAVAARVGLPVLGPKPLPYPRCPPDRPLAGTPSQTSPPQPSAKAPRPTGPTQRPTQSSQFAAKQPPLMKLLDEVASLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPH1</accession>
    <name>A0A6A6NPH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPH1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025563151" description="VWFA domain-containing protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="71727" checksum="96175DA706772673" modified="2020-06-17" version="1">MAAGMRGLEMSPLAHFTTLLTLLTRITAADAASNPAPLVYPSRLTSLQPRTEISDACNLSVLTQGSPRHIALAIDYSTSTLHTDPHSYRTDGARAVVLQLSPEDDLVAVVNFGGEGPARIAYPLGSPKGAIDVLNERDTVRKGSFVGSGVEGGCGQVEGENGAQVIVFSDGEDESDELTRRTAEAVERCNSNGVVVHLAALGGGEDANKVVRKAIERDGGVIRGVSEPEEYCEFLQTVFGRDTVGLADEPDDGQSHVDADDPTEKKPEGDDDKLGKDKDKHEDNDLVVIVTGNDSDAEFSVTSGSDGQAMEFSGNKEAGPMTTDDGQDDTVQPGPLSGSAMSVPAGSNASFPFDINRGERIILAVETNTTGKPMQVTVSNAEDGTELISTETDEQGHAVIGSDVMAADMRTLITIKPPASDNDGAAEVHMVNVEVEAEEVEAEDEPADGTPLAFTEAPMVVPPTPSTSSPLPSSLVPSTSLTGYGETSRSSSSTSSTPAAPRSSSASAVASPTATSTSSPPLSSHSSTAAPTLTPASTTPGDWTWPAPSHPDPKSDDGRNTMQSQCTPSAAPPTSPTSTSSAAPSSGTAAPKQAPCGAPAEEDGASCGSGDEERLPEDGCAELPDRPGSCGNDEDTSPVAPVAPNDCGEEAGDGCEGGDEGGDGAEGQGGEADLAAQGEDQESSASGSKAGLVLMVGGGYGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU3</accession>
    <name>A0A6A6NPU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="32153" checksum="2DACE0A0670BFFBB" modified="2020-06-17" version="1">MAEIATAIETAIKTMTVVVTTMSVTTMNVIAIEMTTASGTETGVQMASVTETEIVADRATAIFRKAPATAYRRRQFQHDGSLGDEESYDNDTFRDTLSFNDDFRNAIPSINLMIGIIAMTPETVTESEAETMPDIMTAGFWPNIRGKIVTIYGESVNHDDRSMVNDAGDSHWRLANASSPIRVYNQNVEERIKASSSTVRMRNPQVQARIAKSARVVQVHNPDLQGQIVKLSSTLRVHRLDERRLGLRLLVLVLGPGGGGMMIGGGAKMLDLCDHSFTSLFHRRRDGAKTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPW8</accession>
    <name>A0A6A6NPW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_117494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPW8"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000009">
        <property type="entry name" value="Proteasome subunit alpha type-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="254" mass="27749" checksum="CFAA2E821CAD4595" modified="2020-06-17" version="1">MSRRYDSRTTIFSPEGRLYQVEYALEAISHAGTALGVLAKDGIVLAAERKVTSKLLEQDTSAEKLYILNDNMLCAVAGMTADANILINFARQAAQRYLLTYNADIPCEQLVRRLCDLKQGYTQHGGLRPFGVSFIYAGFDPQRGFQLYSSNPSGNYGGWKATSIGGNNASAQSLLKQDYREECGLKEACGLAVKVLSKTMDSTKLSSEKIEFATVGKTKTGQVYHHLWTADEIDALLKEQGLAKPEGEGEGAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPZ5</accession>
    <name>A0A6A6NPZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_292480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF135">
        <property type="entry name" value="ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="43"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="473"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="378"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="530"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="686"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="846"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="934"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1017"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1141"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1302"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1212"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="695"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="968"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1026"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1162"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1320"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1362"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1384"/>
            <end position="1436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1530" mass="166401" checksum="13C9B091F6740D66" modified="2020-06-17" version="1">MPKKGKSAPRDVAAPAAITVAAQQSRFHVDLVDPGAVPASSDVAVKDLSVAVGAKEILARADLTLQSGLNYVLAGRNGAGKSTLLKAIADGLVPGIPWSLRILLLGQTRVQVEDDLPSLQLGEAPETVLQHVVRSNEPRERLVREADVLSAALEDQNDPLAPVKARREVTHRRLEKRVDEARQIAARRSGARGLKARKLLIQLEEEVGRSRQRLGVEVSPEELAEETQNVVDLLADVQSSLEAMDAPAAEAHARAVLLGLGFSAESLEMPRSNLSGGWKTRCDLASALCQPTDILLLDEPTNFLDLPSIMWLQDYLGGLIDTTVVVVTHDRDFADAVANELIVLRNQSLERFRGNLSNYERERRKYAKWMTRMKEAQDRQKKHMEASVDNSVKAAKRTGDDKKLKQAASRRKKLDERMGLEVSAKGTRFKLNRDMAGWHTSARDEIEVPQFDPPVHISIPTSPSDLRFPGALVSIEKVSFAYPAKRKSEQVPILRDVDLTIHPGERIGLAGLNGSGKTTLVSLIVGAGDDGASSASSPGALRPTSGSTTRHSRARFGRFSQSAVEELDTLSKQNPELVPLRHLMEVSRGSLLEKEARVLLSSLGLQGQTASDVPIGALSGGQKVRLALAEVLWSPSHLLILDEVTTHLDADTILGLVAALRGYEGALLVVTHDRFFMRCVVEGKSPSKCRGGTGGDEDEDGESSDGEGGDGANVKGRRVYRLTKGRLQLLEGGMARYEEIAATAAGKHKKGRESVTRCHPQPTTVASGDCSAQLAPVRAEKRVACARLHGTIPAAPGGGGKREGSAGGFILFCFYDCCAVAVAVVAVAVAAAAAAAVVCRTPHTCPRTAPTAAPPPVPWSAAMADPAESTPRTAPGDSSRAPGRQPAEKNRRCEYCGQAFTSSSLGRHLDLYIRPKNPKPPDGVHDVDEIRRKRSAITRRQMRASSAAHAQGRRDRTPRAASARLAPPSQPPPPIPEPVDRPEPIFVDSPGHSGGDGGPSVRINEAPWQVTGVINNLPPRAAVPDPAKDPTKHRQQKAEFEQRQRLTEEWEKSKAAELALREVLANVREASAKSTGFDLFDFDPYTMNFPSLCLHVLPAPPTLYSPTPFPTSDSWSINAPGRKQFDALERDVQERLQAHMRARQQQVPPGGSAKAPQPPLGTPSSSSQTSSFLFNPDPRKLSSHISAAFDHWNTLTDQQRQDAWQLELLRSYDRAETSRREAERALEAARREIEQLKSASRRPAANPMFPGLPPTSSSLLLSQQAAREMGRFSDVRAWDFDALVERWRGVVQETRRRQLGLGMSAQQRSLSVSSAPPPGSNTTAAAAAAPQTASVPTLETPISRKPTQFSSGPGKSGDPDASSDQMDISGNQEPAQWSQNPGLQAQQQQQQQQQQQQQLAHQQQQHQLQMQHQQQQQQSQHMQRQQLQQVRQAQHHISSASPHGLPHAPPHHQQLGSSQGHIAQPLHHQHHHGHQQIGQQQLMPSDDGKMRRQSAGYMDPSAEQVQTHIGGSMSMEGIESNEAYMCGRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ75</accession>
    <name>A0A6A6NQ75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mss4-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_292120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ75"/>
    <dbReference type="OrthoDB" id="5290969at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF3">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="133" mass="14654" checksum="59189A618D5A713A" modified="2020-06-17" version="1">MNGSCQCGAVRFTTPTPEPLSLYHCHCIECRKQSASAFGTSAIFPGFSIANEPAIECWTRTTDAGRQLDCYFCKRCGTRVLHQRRGFDVVSVKAGCLDGDLDWGKASHIWCKRAVVPIPEGAVRFEAQPPETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ78</accession>
    <name>A0A6A6NQ78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_424295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ78"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30607" checksum="56576D9A10BB6ABE" modified="2020-06-17" version="1">MALSSLPTHFGITFTSTLHSKPEGLTEPKSIKLPSPFVVAIAGGSRGIGLSIAQAYAEAARTCDVAQQEDVDKFSAGVKAKFGRLDVAVFNSAKAPRYLQDADGTLRLSSHVLEDVEEFHGVTMTNFLGAVYLAKSLLPLLMETKDGMQTLICITSASSHFGSSNVTPASYNISKLAMNRLIETVDSDYRDQGIQSFAVHPGVVLTDLTARHSETVAGDFWKSALTDDPRLCAGFLVWLTKEKRQWLSGRYLAANWDVEELEAKREHIVNEDALKFHMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQV9</accession>
    <name>A0A6A6NQV9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sedlin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQV9"/>
    <dbReference type="OrthoDB" id="10252102at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21518" checksum="2C449D9E7A79A301" modified="2020-06-17" version="1">MSYYFAIVGTKDNPLFEHEFGTFRQGGDGIARFRDDARHMNQFVVHSSLDMVEELQWTTGQMYLKNIDRFHTSYISAFLTPTNIKFLLLTCPDPTSSTLLPTPVPTPSSTASTASLSRSTTASSITNTTAAAGSGSAYATSYNPTAPATEDAIKNFFMDVFDAFVKTSMSPFYALDRPITSPIFRARVAASAKKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRI4</accession>
    <name>A0A6A6NRI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_291810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRI4"/>
    <dbReference type="OrthoDB" id="2163491at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051747">
        <property type="term" value="F:cytosine C-5 DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF4">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="2">
        <location>
            <begin position="545"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="780" mass="88014" checksum="293A3FF86C967BA1" modified="2020-06-17" version="1">MHASGTLPILQAPPQASEGIIRNWTRFHHNNAVTLPTTIQPSQLHNYDFAPLSPSPLYSTVLHSQFHFQGPPSALEPVASSNANAENATRKRGRPRKSALLPSGLLEATSANDQSSPAPESQPAAKKQKTLKIQEPENERPAPRGEPLVWADDRTALCESLPYFRAYQGACYSNECRSKSFLFDKYSHSRDIITDKVVLARAGGGMSRKSLADEMEQSKDQENSSHVRSTINSMELYVPVVIIFGNENSKIKSKMPHIYNVGDFFKITHVWYEKSDGLIVIRFRFEKLDHKCPGWWHPQDQESSQLGAYGPIHNQTCTCCGHSSPQVYKQYWICLNHACEQFWKPGDNNSPHIAEDSLEYDERFLHAFTPWPSSIAPYPLRPALMPLEEYHNIRSDESENAIKGIVCPKCGRCTGRGEFYGLVCGNPNCDFTYKAPKEVIPPIALHDRLKPRTSGFAIHFSDWWDSHIRLQVTLANNYRTHRYDIPGIGSVFHMMANKVVNEEKGGPDDMFVELQEKVESLGLERRYLKEGKLNHRTNHFSMNFGMPYKYVAKNPSKSFEEAPDAVRETRSRMEWACRQCLGNGWDGTNHHGFNELLCVGYHGKNKMDYHDDGEKGLGPVVAALSIGYPADMRFRLKSKHFTGRMRQGNLLLEPPILDWACQNAEFRKAALSELAQVEGSEARSQKIGGIEAQLKARTKGRLGKDILTMSLNHGDIMIMSGAAIQEYIEHTVVPLGRKRFALTCRYIDPSSVDKDHQPPYAVEEDKIKYDGRALAQPSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSD8</accession>
    <name>A0A6A6NSD8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_325745</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSD8"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.220">
        <property type="entry name" value="Fungal kinase associated-1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031850">
        <property type="entry name" value="Fungal_KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043024">
        <property type="entry name" value="KA1_sf_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16797">
        <property type="entry name" value="Fungal_KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="108"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="518"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="649"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="747"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="837"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="591"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="694"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="862"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="936"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="972"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="995"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1247" mass="139227" checksum="E0F9CE387776B9EC" modified="2020-06-17" version="1">MNRNPPPQPRQRRRALGEVQPRERPPASPRHKRVSDLSSALQGLPHNQSLVPNGALSVRGSPSKATGPNGKRLSGPIPAPTYNSNRNSATSTVSPTAPRRLKTHIGPWQLGKDIGRGACSRVREVRHCYKGTIGAVKIISKATAEQLSSASLANLAKNTANEENMFASRKVMPLGLEREIVIMKLLEHQNIVRLLDVWENSNELYLIMEYVRGGELFHYIAERRGLEEMEVVFLFRQIIAALLYCDRLNIHHRDLKPENILLDKSTFEIKLVDFGMAAMQPQGRFLSTPCGSPHYAAPEVINAGLKGTRAYDGGQADIWSCGVILYVMLTGTPPFNYNGEREDLHNLFRAISKGQYVMPDGLSPEARDLIARILIPNPTHRIGIEAIWNHPFLHKYDEEFGIDAKSAAIEHWIGPGPHIENWKPLQRHEIDREILRNMRTLWHSEKEEVLIQNLLNDELNHEKYFYSALIKHRNEIMEDYAGLPAGVGYSPSDYHHIPGRSRAATRRSQSQYSILQENPVTSKQSLLPPQSEASYDPFRASKEPLVDSKADYTNVTIHRGTSSASRKTKFRSQRQQGSLRVETLKNRKGGSQLSRSTSRKSSPGQRSEGTRRTTQSRSSISSSTGGNASSIMVRPSSIHKRGVSFAHLRKTSAGSGPGPDTPSPKQTVPLSRRRGDPNFDSRASPQRPSMRPAEALRSKKEGGRDNNAKYSRAVVPNPYIENEARKVSTELEKVCEEAFFRTSIGSSARTSITDRPTPYETPPSSVSNQESGYAAKEAARIQARGDSRQRPLPPIPNDQANPTARELLDMRERLATRLACNRGTAEEEHLRKILAELDRLVRQPPPPSVDNGRRNVSAPDPRTTELQRDLPIISEEHRSSGVNPLSYRDEYRSATDPVGKAQPRALQKADTIRLVDPTSPPQISPLNIKKAKNLEANENSPRSASAEPSSLHTSYAGPVGSERPKTAPHQGKASTQSDSTKGSALRKKRSWFRFNKTENSSDRKGSWISDTFGSPDDRNKTATSSAQHRNRTLDRSSSASSEFPMRENARDFSGKRKFLNIFGKKRIPKKDAIGLEVASPGDLSNPSLVSTFDNVEGKEAYETVPSSRANDFQQNWFARFFHIKPATKLLCFQVGRGRARQEIVRTLKDWRRFGVKDVSFNRASNTVRARVDKDNHLKIKPVELMAELFVVLEHGRRAQLSMARFTQTRGAASSFRKAVEIIEDVLNSKGLLVEDGCKKQAMCEVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSJ3</accession>
    <name>A0A6A6NSJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Noc2p family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_352535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSJ3"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="725"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="725"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="758"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="783" mass="88144" checksum="42E15BEF37AA1F67" modified="2020-06-17" version="1">MAQTKATKKFEKKHLKDTLKRRKELAKVKQRHQRNDKRKARRAQEHESDDDQPKNDAAPKTSSKRANGGDNKAFANMSVDEFFQGGFNIPEPVKQPAKKTGKRKRAEKPQLEPEVDGSDTSGSSSGHELAEDSHIQDNTGSEEESEDETAHKEQLEKLAEKDPEFFKYLQENDDELLNFDDDADLDGLQLSESEDEETPTKKRKKGNVDAGEDERAPDNEITKAFVHKWRDAIHNKQSLRATKEVMLAFRAAVHVNDEGKQFKYTISNPDVYHELLVTAMECIPKVVRHHMPLKETAGGKVRVSTDSKKYKNLAPLLKSHTHSVTVLLETLSDGATQRRTLSSVELLLPYLLSFKKAIRELSRVVVEIWSDSGNTEASRLAAFLVLRKLVVIGDPGIKESVLKASYQGLVKGSRVTTIHTINGINLMKNSAAELWGIDANIGYTSGFTYIRQLAIHLRTSITNRSKDSHKTVYNWQYVHSLDFWSRVLALHCDSLREAKAGKQSPLRPLIYPVVQVTLGALRLIPTATYFPLRFQLTRSLLRLSLATGTYIPLAPALHEVLASAEMRKPPKPSTLKPVDFETAIRVPKSYLRTRTYQTGVGEQVAELLSEFFVLWAKNIAFPELALPVVVMLKRWLKEVSGGRRGGGSRSGGAGAGNKNGKVNGAIVLVVQKLEAQSKWIEARRAKVEFAPNDRAGVEGFLKDVEWEKSPLGAFVVGQRKAREERKKLVEEGRRREERRRKNNEKDSDAEEIENRFEDSEEDMDVDGDVDIEDIDGDEDEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NST7</accession>
    <name>A0A6A6NST7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_291174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NST7"/>
    <dbReference type="OrthoDB" id="4463286at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="49272" checksum="B830BBE61DF827F4" modified="2020-06-17" version="1">MATTPQKPSTANNSTTPSGNAASASASASASAAPTAPPPPPPPPAEKSTSRSPTGANHAGTSGTSAPQHAPKIIVKKEPASPDLATSRHRPRRLDLSSNNAVAVGGRSGALSARPSAPLDSRDSLREVGLACLSPGFHTHDPSMREQLQRSIDVREQQRQIIEARQKTAKDPTGAGGGAGPHDAPGGEAPPGGIKSARTPSSRRKGPPPGLSITAPSHQNFAAERVVQSAPLNQSFTGLQPAAAGGPGANAGPSSLSQTSHIHHVPATQTTNRLPPISDVFAADNLHPSRESGSSSSRPPAFNHSPNRSSHAAAANQGPVRSPGFPPGAAGHPSHHGAPLTSRPREYKSAEEAVQSLTGGREELLPRLVHYGGHQPPTPPSPIPSKGHGGAGGQQHHGPGTSGIQAPPASGRRRARDEYEQDMGSPPLGRGRPGGEERRRAAPAAGLWGESRGDSPEAQKRKKEEFMSLCSRAWDLLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTD3</accession>
    <name>A0A6A6NTD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_77240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTD3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="18880" checksum="A372D38DC26119E8" modified="2020-06-17" version="1">MQLTSRFLIPEGSDSDWERRQTAPLRGQRRRPLREELLRSNPSRRSTAIPAERSVPIVGGGTGHGPWQRRTRRGRAGFDTYLERQRGRGRAESVERAVVKTATAAGPIWTRTGPGHGVQTRNGFHGTGSPSGPGSPPPPPAGPVRPTFTSARAVSMQLPRAAFMMDGDAPGGQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTE6</accession>
    <name>A0A6A6NTE6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_351734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTE6"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF36">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="348" mass="36464" checksum="F3A3CB072C898134" modified="2020-06-17" version="1">MATPTLSTPLCKILGIKYPILLAGMARTSGGPLAAAVSNAGGLGVIGGLGYTPGQLQSIIDEIKANLTDKSSPFGVDLALPQVGGNARKTNHDYTHGQLDELIDVTIKNGAKLFVSAIGVPPKHVIERLHGAGILVMNMVGHPKHAVKALEAGVDIVCAQGSEAGGHTGEIPSSILIPAVVDVARRYRSPLTGETTMVVAAGGIKDGRGLASSLMQGAQGVWVGTRFVASVEAGCSKLHKESVVSASFGDTLTTLVVSGRPLRVRLNDYIKEWEAKPEEVRALTEQGVVPLARDMEEGKDVDIPFLMGQVAGVIQDIKPAREIVVDMVREAVQMLNLGQSYVSSQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTK6</accession>
    <name>A0A6A6NTK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_351112</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTK6"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045862">
        <property type="term" value="P:positive regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041312">
        <property type="entry name" value="CHIP_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18391">
        <property type="entry name" value="CHIP_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="7">
        <location>
            <begin position="209"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="286" mass="32567" checksum="DBA63A56AC6EFAFF" modified="2020-06-17" version="1">MAHLAEELKEKGNAHFRRGEYESAVTLYGAAITKNPRNPLLYTNRANARLKLEAWDEVIDDCLKSIELMRDNMKAFFYLAQAQLAINHPNEALSSALTAYDLCVHSVSQTSSASLISALVVKCKRRKWEARERERLRRQSSLLAELEDRLERGACDELAALEARRAAGEVGEVEAAEERDEVSKTARTKLDDLRSLFAIADPSKMTKREVPDYLIDNITFEIMHDPVVTRNGHSYERATLIEHLKRSPTDPLTRDPLHVSDLRPNVALRQACEEFVESNSAWIYDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTQ7</accession>
    <name>A0A6A6NTQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_373621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTQ7"/>
    <dbReference type="OrthoDB" id="3892274at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="117"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="130"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="209" mass="23387" checksum="3E4375E440264EAA" modified="2020-06-17" version="1">MPARLRQDSFAMETQQYDYWVPQSGYMNGGLYDSASSLSPSPKMSTPYDHLAMNMPLGQIPEELSYGYQMALTPSDFGSADESSPYCSPSSRPTDVAYIPAPPPQPAPERTHTTSGRRRAQNRAAQRAFRERKEKHARDLETQLAAMTEKYRSLETSHAELTAAYEKLRKTIELLTQPSDGEIPSNADTLRKLLDILHGEIKIKTESAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU07</accession>
    <name>A0A6A6NU07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU07"/>
    <dbReference type="OrthoDB" id="4097008at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="71" mass="7686" checksum="521F4E257ABB4A06" modified="2020-06-17" version="1">MLRIAASIASGAFRWGAEDDAREGERIPCSWESSGDEEDAVDDEDDFGIPLRNLGAGVRRRDVSSASSELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUJ2</accession>
    <name>A0A6A6NUJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_350766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUJ2"/>
    <dbReference type="OrthoDB" id="4157259at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="10952" checksum="8E1D15F3BCCF4CB7" modified="2020-06-17" version="1">MPAPAPTPAAVGGERHFRERRPSLLSASLARSEHVVVNVGHPDAPRLISCVKASQGFDWNQDIFLPSYLDHDSIDLERKQDPVEDIVLTEEEAAAIYPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUJ8</accession>
    <name>A0A6A6NUJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_75291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUJ8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17896" checksum="A0BF87065B10FDD5" modified="2020-06-17" version="1">MLYLSHKPPVLVIRRQICTNSQLASLLSPPRPNCPFSLRLVAVGRTLARLLQYQVSVTAKALSLCLSPPFGSHGRTHTYTDTPHCHERFVRFATLKLCSADSHRTRSRPRLLLLQLTRGANRTLRARPFPSCRRRTARTGRTLHSPRRKPRAADARQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVB2</accession>
    <name>A0A6A6NVB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_69954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVB2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19038" checksum="AB278B7C46287AFE" modified="2020-06-17" version="1">MNKDGRTLHRSGWCSTPICFSGGGVGDAFTKESLGFQLRISTAAWLLAAWQRRESSVGYARWIAWAEFVLPAGFALFLIAHCPPPISALLLSCFSTCSTGFCLPPYSFLLITNLETSALTTLSAPETFLLGLYVTDYCMENDCWWWDGRAEVCAIAPRSRSSGRTVRLQHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVE4</accession>
    <name>A0A6A6NVE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TBP-associated factor 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_66214</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVE4"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000033">
        <property type="entry name" value="Transcription initiation factor TFIID complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.770:FF:000001">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="8">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00076308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="449" mass="49473" checksum="AB1D15CF2F883E59" modified="2020-06-17" version="1">MSVWNPENIRDVAESMGVSSLNNDIASALARDVEFRITQVLDEALKFMRHGKRTTLTTQDISQALRVLNVEPLYGYESTRPLRFGEASLGPGQPLFYVEDEEVDFEKLINAPLPKVPREISVTAHWLAVEGVQPSIPQNPTTADARQQELLPKGPGANTNLAALAGHDTVSVKPLVKHVLSKELTLYFDRIIGAILHDTSEENRLAALASLRTDPGIHQLVPYFTQFVAEKVTHNLKDLFVLTQMMHLISALLDNPSLYLEPYVQSIIPSALTCLIGKRLGSGTEANPLAHFDLRELVASLINAIARKYGAEYKNLRPRLARTLLKNLLDPNKSFGSHYGALIGLNGLAGAEGFRTLVLPNLKYYDVLLKEGLADETRKLEAEMVLGAILRGMHLLEKESKGMANREHSNGSAELKEAVQERIGEVVGAHVFELGHPKMIAAVMNASVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVG7</accession>
    <name>A0A6A6NVG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetamidase/Formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_365478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVG7"/>
    <dbReference type="OrthoDB" id="9975579at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054833">
        <property type="entry name" value="FormamaseFmdA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045496">
        <property type="entry name" value="FormamaseFmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="411" mass="44976" checksum="9D19B1DE4AB42AF9" modified="2020-06-17" version="1">MGKGDIRTVAKVSLETPPPQQKILHNRWHPDVPFCGKIANGEVVKIECLDWTGGQIKNSDSADDVKNVDLTQVHYLTGPFEIETAEPGDILLIEIQDVQPLPEQPWGFTGIFDRRNGGGFLDEIYPKAAKAIWDFEGIFCSSRHIPGVRFAGLIHPGILGCAPSPEVLAEWNKRESELITANTLDRVVALPPEPQSVHAGSAEGEIKDKVGREGARTIPGRPEHGGNCDIKNLSRGSKVYLPVHVPGAKFSVGDLHFSQGDGEISFCGAIEMAGVITIKFNVVKNGMAEMGLKSPIYQPGPVEPQFGPGRHIYFEGFSVDEHGKQHYMDATVAYRQTTLRCIEYLRRYGYDDYQIYLLLGCAPVQGHIGGIVDIPNACTTMGLPIDIFEFDISPGAPVKKMDMGSCAYATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVK1</accession>
    <name>A0A6A6NVK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_289475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVK1"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="7393" checksum="1925E8B1757E0AEE" modified="2020-06-17" version="1" fragment="single">IHSPKAQTHVLQNGKRILPAIDQMREDVTGIIETADALQGAPDARKRGEETEKVGVVRIALVGVAPVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVQ1</accession>
    <name>A0A6A6NVQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_348871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVQ1"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF263">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="176"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="325" mass="36982" checksum="1A616FB340805A3A" modified="2020-06-17" version="1">MLIARRFFHLPRPHLRHHHHHNHNHNHHHHHRHRRQLVYPNSTPHAPRPHSTMATPSEPSTKRQRTTRSGSTPAYELLYHPVLPGRGEYVRLVFEATRTPYTDVANASPTGYDAVAALCQSDTAGWDGDGNPPVFAPPALRVKGAGAEDGSDLLMYQTANILGYLGWATGMVDQGDEVARAWVAELVMTALDWNDEAHDTHHPITSMDYYEDQKPEALRAATAFRVHRLPKRLGYFSRVLSHAQPYLALNRLTPADTTLFQVMDGTMHAFPKEMAARRAEFPAVFAHHERIREEDGIKEYLASGRRLAYGDGIYRHYPELDRQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVV5</accession>
    <name>A0A6A6NVV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_289228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVV5"/>
    <dbReference type="OrthoDB" id="4138492at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF11">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="141"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="572" mass="60292" checksum="A73F0C98AFBE7785" modified="2020-06-17" version="1">MGLLDDLDALLLSLFAGSNALTILLTVAVGGFLAFLYYDSPEPDTHPMLLARGASASPVRMPGESAVYRSQELPHGYPLRTGLGVKYPGAPAYSGGKNGDLRDIWRRVSGKLPLEGGDADANTGKILTVLGKEEVVEHDIKELEREIAAVGKFLKGHKAQRVAVYLPNCIELLAVVFAGSFFGFDTILVPYNQPPEALTSLLRETEADSLIAEAGSLPLEDVGKDVPNLHQVVWVVEKTSRHVDWSEVPAGVGGKIDVVVWHELSREQNGSSAELPADDSKQTPGGIVAVWQVAPGAQSEIVEFSQANLTAAIASHLSVLPRPHRLTPSDLFLSAESLTHTYALTLTLAALFSHATVALTSVAGAGVPLAASSVSVAPTVIVASAETAASMHEEEREKLSASTVRRVAHTAQTRVLAGGAMPSPDGMWARVGGGKTGLGTEPGKLRLLYVSERAGMGGHKPPMTAQELSDLRVFTGARVVYALTAAKVTGAAAQTTLFDYRNEGKDKAGKPHVHFGVPPSSLELKVVDARGVQTTDDKAEGEVVAMGPSVAGGEARLGFLGRFRDDGCLAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW12</accession>
    <name>A0A6A6NW12_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_349016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW12"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF104">
        <property type="entry name" value="PROTEIN CAP1, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05595)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="549"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="853" mass="96292" checksum="6ECB25149B6213AC" modified="2020-06-17" version="1">MSLLPGTLFVLLEGLAAPSRFGSLDGPPSSAEQRSHASSGLVAILTITATAALYPQYMTSSVTALGLCYALLTAGSLVLLERAITSIKDDKYAGGGGFVSANGSFSRRDSVSQAQDNVSGFCLRDFSGAAALACLLGSFWFEKFYTSKRIVYEPGLRGEVEDDWKYSFFLWALFGLFGIAATVVMNFSMLAMIPSYGAFRLGLVALGAPLLARLSISHSFTQIWFSLVCIATGTLLFHDLTISSPAQQLTFGTRRRMRARHLVILVTIVSLIGLTLTHLRHPFSHSSGGNGKIFPPPRATPEKPLDPLPVGTTSSHPIDILINQNDEQFAQLVERQSKTLEEAVAEYRRRYGMHPPPHFDRWFEFAKRKGVVLVDEFDMIYHSLLPFWALSPATIRARVKEALGFSNNLIALRIRDGQPVKINGGQEWQRKATMGMMKSFVDLLPDMDLAFNIHDEPRVIVPHDQLSRMIEIAKTERLPAALAVSEPKNSFSPNPGDLGRGNRADDVKTTRFNVFAHQQTWTHSRMSCSPNSPARYFDESISDNYTAYALGELGFVYNHTAFSDICNSPSLRHTYGFFERPNAFNIVHDLIPIFSQSKISSFQDILYPSPWYWFGKVEYDESKEYAWEQKNNSLWWRGSTTGGFSRDGGWRRQHRQHIVKMLNALDHAKVLTNKAGTDSSAGDWHVKSVPRQEYADIIDVHFSHVGQCDEGDCDAQKEFFEIVKPSDQQDAWQWKHLLDMDGNAFSGRFYAFLQSKSLVYKMAVFQEWHMEWLRPWTHYVPLSLKGDEWLETVRYFSGEEKGKTQGQRIAQEGREWAGKVLRNEDFEAWFYRLLLEYARVIDDNRETIGYGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWG5</accession>
    <name>A0A6A6NWG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWG5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="184" mass="20538" checksum="44848BD0CFCDABEC" modified="2020-06-17" version="1">MQPRRHDVLPCIPPSADPSNHVIARRASCLSRTTLLPAAHRRPPLCHLPLIPLLPRSLSHHPRQTPYAFPRPRPGQRRPTVRFALPQRWRAPHRRRHAAPRAQRARAQHARPAASALAQRGRQPPPALVGPFLISRQRRRAKGRRRRARRRAAPALALLGRPRAPRRQVCAGAGAGGLDRGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWN7</accession>
    <name>A0A6A6NWN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_288070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWN7"/>
    <dbReference type="OrthoDB" id="427213at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000036">
        <property type="entry name" value="Putative sulfate transporter YPR003C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="581"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="637"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="703"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="850" mass="91494" checksum="055A50201AA7B8F7" modified="2020-06-17" version="1">MPSSSSSNSRRHEGPRDSGGGEPSAAERSPPPPAPPGRPQTLDDGSSGTRAPSSPAAARDLPRLEDDGIHPTAPDAASIRSADASGATDAAPGAPGAEPGAVFDETYFDRPTVRARLLSHKNWDQASGCGSDNCAHGTFSPRPQTGGSGGGDDASRAGYGGRYPGGLGEYGHTPDPAHALLGDAVADGLLGGGQQGGKVSTTKWLASKHGLKNRRSMYLQYYIPCLNWIRQYRLRYLWGDATAALTMASFYIPMSLSYASNLGHVPPINGLYSFVFNPVIYAILGTCPMMVVGPEAAGSLLTGEVVRENIEKGHVADKDGRKSAEIAGIVTAMAGGIIFVAGLCRLGFLDNVLSRPFLRGFISAIGFVIFVDQKITELGLARIAEHVGGVAHGSSVQKIGFIFSNLGKSHGLTAAVSFGSFGIIMVCRELKKRLQPHYPGVAYVPDRFMVVLLSAILAWKFHWEEKGLEVLGEVRASGHIYSVHFPFEFSHLKYVADAFNTSIIIALLGFFESSVAAKSISGSKKDDDGIKSMPVSANRELVALGVANLVGGFFMAIPAFGGYGRSKVNASTGGRTPMSSIFLSLITVFCTLVLLPYFYYLPKGVLSAMISVVAYSLIEEAPHDIRFFLRIRGWSELALMLIIFFTTILYNMKTGIAAGIGLSLLRLLRHSTRPRIQILGRVPGTSDRFENAELDPGRLEFVEGCLIVKIPEPLTFANTGDLKSRLRRLEDHGTQAAHPALPRVRRDEHNRNVIFDVHGVTSLDGAGAQVLSEIVHAYRERGVRVFFCRVPSERSDVWRLFLASGIVDMCGGRSHFVQSVPEALHLTEVESLEEFGTFLADGHGECEMMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXI0</accession>
    <name>A0A6A6NXI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_364611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXI0"/>
    <dbReference type="OrthoDB" id="269496at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="21792" checksum="453CD963C97AB3F9" modified="2020-06-17" version="1">MAARRILNPALFICDLQEKFRPAIHEYPKVIATTQKMLKAYIPVFATTQQRAKLGDTCSELGLDSPDGYATQVHADKSLFSMWTSEVQSALRAHSPDSHDVVVVGIESHICVTQTTLDLLRAGHRVYVLADGVSSCNKEEVPVALARLRAEGARVTTSESWLYECMGDAKIPEFRAVAGVVKETKESTKEALQSLCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY18</accession>
    <name>A0A6A6NY18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cryptococcal mannosyltransferase 1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_287663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY18"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 69 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="464" mass="52359" checksum="F0B692EA58969A81" modified="2020-06-17" version="1" fragment="single">RMRHYLRNTALFLGAFNAIIILYVMFAFFSKPSYTYYPAHYKALARLANDSEVAGRANPRGEKVFIAASIVDKNGELLGGQWGTSMVELVDLLGPNNVYLSVYENGADPRAVGAMRNLSESVQCSSSFVADNLTYDQIRHIELPNGESRVKRIEYLAEVRNRALRPLEQSTPARRAKRNGRRSADSTDVALFESHHGTPAYLTTFDRVLFLNDIYFSPVEATQLLFATNSNDPARNFPRARYRAACAVDFINPFKFYDTFASRDLDGYSMGLPFFPWFSREGSHTSRDDAQAQSDAVRVRSCWGGMAAYEAYWFQDQDRPLRFRAEPGPYWDASECCLVNADLANLPQPPEPELVLDAVWNVSNPGIFMNPFVRVAYDAGAFHWERIARRPEQIYAPVHALLGWLLELPGYNPRRRDVREGGFCGARRILLINERPEVGESRWQRTVVPEPVEATATATPGAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYA8</accession>
    <name>A0A6A6NYA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAM dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYA8"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF105">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="327" mass="37025" checksum="F68A2BC702DCC86B" modified="2020-06-17" version="1">MADQAASQTAAGPSTTPLDIQGATQNDLEVADDETDSAYDDDDVASDTTSLRSSIEDYHFQNGRRYHAGPNDEQQSDSLDIAHHIWTLTKDGNLHLAPLQNPQRVLDVGTGTGIWAIDFADHYPSASVIGTDLSPIQPLSVPPNLQFEIDDCCMDWTYRKESFDFVHIRSLYGCVADWPAFYEQCFKHTKPGGWIEQSEMGVVPKSDDGTVKPDSIFHQWGEVSLRAGDEFGKSLRTVDEMKQGIKDAGFVDVVEIRTKWPMGPWVKDEKLKEIGRWNRLHWESSMEGWCMFLLTNYLKWSPEEVQIYLAKMRAMLRNKGVHAYQDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYB9</accession>
    <name>A0A6A6NYB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GLUT4 regulating protein TUG-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_345901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYB9"/>
    <dbReference type="OrthoDB" id="440781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16105">
        <property type="entry name" value="Ubl_ASPSCR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021569">
        <property type="entry name" value="TUG-UBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467:SF1">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11470">
        <property type="entry name" value="TUG-UBL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="397"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="554" mass="58570" checksum="0CEB56A3F9ABCC24" modified="2020-06-17" version="1">MASHVVVIDANARRHTVRTSPGTYLQDVLAEACSKTGGLSPDHYALKYNGKPVDLSRTVRLSGLPSGARLDLVQASRSAAVVAVALQLPESERNARLTHKFPSTTSVWHILRAFECGAVPGTPTNLNLTQRGIPSAGAGAGRLNYDMPVVNVMGRELASFVDLQKNLSQLGFHGGNVLLRLSFRNSGRPLEEAMMEITMYFKSTEEDAAKLAQGAHSGSAGEAQSRPQGQPPPTDATEARSPPAAAAPAQDESAAIPEIQQQQQHQQQQKGEEEHPSTSSQPIQTPPAQPATTTMPSSSAPATQTSITTETLPSASSAADGPHAKESTIYMPSSSATPQAAALTYNPADYEPTEFHAMLHQSRLNSASRNQRLLSDAELAEQEKRARERIAAVRGITVKARFPDGWQAQTGFGRAESAADLYGWVRGLLAAPDHAFVLTFAGPQGRQVHLQEDGKKLVLDLGWKGNWLVVFAWADGVPAAVKNAPVLKQGVRGSAVELKVDMSPRGTDTAGGKSSDGGSAQNGGAAAGSSKHGGGSKAEKENKLKNLLGFGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYF4</accession>
    <name>A0A6A6NYF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYF4"/>
    <dbReference type="OrthoDB" id="5367275at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="273" mass="29847" checksum="44930829EF2B1009" modified="2020-06-17" version="1">MLFAGLAREKSPARRVLVKKDPALETSRRLLRLAARRYGVVLKAMETVVEGADESLPSSYSLAHLFSLTEYDRLLYLSPPGLLLSSYPLDLLLAYAPPSPLAVLPASSAPQHPPDQPFSTSLLLLTPSAPTHARLLAARAARPQPDPSLLRSAFPSPALLTPALLSSLADGFAPLSDTSSLSRPEAGDEAGPGAEPFDPGRWRATRGWVRFAGDGGLPAPQVDAGWRARARWRPRGRDEGRVWEGLYEEFRERRAEVCGLDLEGWRRGVEARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYR1</accession>
    <name>A0A6A6NYR1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_304602</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYR1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="482"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="532"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="425"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="680" mass="76605" checksum="9489C6AC8B23CEF8" modified="2020-06-17" version="1">MSFNVPRNVPTFEDPRRRYEDVIWSSSGRSRFASGENGHAQGVADRLGGMFASGGDLPMYKDKPYYSSSRRRRWYKRKRVLASVLSVVLVALYWFGLFSSSDSKPGASRLWQGGFSPRPSGVVDWDERREAVRDAFKLSWSAYEEHGWGYDEYHPVSKKGRHMVEGGMGWIIVDALDTLILMNLTTELEHARTWVSKSLTYEKDHDVNTFETTIRMLGGLLAAHYLSTTFPNMAPVNAAQTGGDDLYLERAADLASRLLGAYESPSGVPYASINLKTMQGIKSHVDGGASSTAEATSLQLEMKYLAKLTGETHFWEAAENVMKVVDDNGAKDGLVPIFIYADNGHFRDKNIRLGSRGDSYYEYLIKQYLQTSKEEPIYREMWDQTVAGIKKHLITYSSPSNLTVLGERPSGLSGSLSPKMDHLVCFMPGTIALAVTGGKTLAEAMSSTEWGSQQEEDMELARQLMKTCWGMYKVTETGLAPEIAHFNMYSPPHMMEEGTLHSPDVLDPAPDAEWKQDYIIKSADRHNLQRPETVESLLYMWRITGDPMYREWGWEMFQSFIIHTAVPHNGGFTSVSDVTRIPPPSRDNMESFWLAETLKYFYLLFGPDDVLPLDQIVLNTEAHPFPQFSMGPLFKTGWERKPRDAEGNIIQNTVRSELSNEDSNSGSERVIQTAHVTKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ19</accession>
    <name>A0A6A6NZ19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="11">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_286820</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="11 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="11 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="11"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ19"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000002">
        <property type="entry name" value="Isocitrate dehydrogenase [NADP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006156">
        <property type="entry name" value="PRK08299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="6 11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 11 14" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 11 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="16">
        <location>
            <begin position="12"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="97"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="312"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="12">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="12">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2456757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="46420" checksum="6FF19CD82285D52C" modified="2020-06-17" version="1">MATANRIKVKNPVVELDGDEMTRIIWKEIKHKFIYPYLEIDLKYYDLGLGYRDQTEDQVTHEAAEAIKRYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNHLGGTVFREPIVIPRIPRLVPGWKEPIIIGRHAFGDQYRAKDRVIPGEGILEMVYTPKGGKPESIKVFSFPPGGGVAQTQFNTAESIAGFGHASFKLALDKKLPLYMSTKNTILKSYDGRFKDIFQELYNSQYKKDFEAAGIWYEHRLIDDMVAQMIKSAGGYVIAMKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLAQRGKLDDTPELIAFAEALEKACIDTVDIDGIMTKDLAISCGKKDRDSYVTTTQYMDAVERRLKAGLKQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZH3</accession>
    <name>A0A6A6NZH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_46653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZH3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="231" mass="26845" checksum="6D33B7D19FEE14BA" modified="2020-06-17" version="1">MGWVGCDSMQRTAELAMGRMEVTCGRLLHLGFPQFPRTRAAVSGTELSAETVRGNVVSSDTTLWIAGREIQDQQLSQIVYVKAQWVKIHFRYLSHGFYQNIRGPKWLWLRYGYCWIREIRPKPVEGAQRWAYYTLVVLIPRISADGSLHEALVFLELDELCISLECFLVIRRVGDTCDVFERLGPVNPHDPNSYEELRDPLLFRKQRLPYFIPESDSVIKPLREWCTVRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZK9</accession>
    <name>A0A6A6NZK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_371971</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZK9"/>
    <dbReference type="OrthoDB" id="2020972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056026">
        <property type="entry name" value="DUF7607"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24580">
        <property type="entry name" value="DUF7607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="442"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="778"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="287"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="354"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="718"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="984"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1028" mass="117303" checksum="B851F0A545252CD0" modified="2020-06-17" version="1">MAGPVDPWDWTVDDLVANLCKSRRLWQGRPSSILPDPIALEHSLRENSMDGATMLSYVDDSIIREVLGVRPFAMRGAVRYAIEKLRSASHKYAEYTENQRSANAQDGYLSSHSATTHPDPHPNDPASSVPHEDNKSLPPLDDDSDTESFSASVWEEIQRDIEEDEEVKTQVERETLTSDEVEDIIDRKIEELVEAWKRKKLPLREKGAWSLWKRSRHPQSRSKLQKYFAQEVERLNERLARLRKGILDELWRKATDLERQGEIFEETIYQREDCVWRLSVLAQKTAPQRRNRPLKTITSRRQANPRENAEDSEELGSDSVASTDDNPEDFIEPDEDRIEMDVDIPSLVDKTLTNGEFSQPHQHPTVAHSSSPQIKESPSHQVEVKSSDPVTIIDLTSDRGNETDKASQSGTAATSHASMAIPAMASTSEVAKWAWSELEEKNDPLIQNWLNELRSWVPVPYEENIGHICHVDADQTVSERIRTVDSWCSSKGILMMSYDMFRILVSRKDKQKDKSREDDKTLTEISRQLLNGPDVVVADEAHFLKNPGSNISQYASQIRTKSRIALTGSPLSNSLREYYAMINWIAPGYLGNPIEFKAKYQEPIEMGLYKDSSHADWRYALKSLRILEKNIGPKLDRKDFADVESQLPRKVEFVLTVPFHDVQREAYKRFVECQEAGIMTQKTINLATLWAWLTAISLLVNHPFIFLEKLKDRHSQALRAEGSRENSDDEIPANPDQQEENPSIWKSILADDAIDQQIRALQTISDLKDPRFSPKMALLLQIVRLSKEAGDKVLVFSHSIPTLNYIEALLQRESELIYERLDGKTKVSDRQNMANNFNEGRVDLFLISTRAGGQGFNLQGANRVVIFDFAFNPGWETQAIGRAYRITQKKPVFVYRFIAGEGYEAELYKTAAYKTQLAYRVVDKINPVRASSKPSDYLFSPRPIKKNDVQGLRGKDPKVLDKLLDSAGSLIFDLATTDTLREEADEKLTKEEEQEAENEYQRRLQEKNPATLAPGANQLRLRPKHLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0D9</accession>
    <name>A0A6A6P0D9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_391409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0D9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19169" checksum="ED6394D969E8971B" modified="2020-06-17" version="1">MAEARAGQWRPVLRPGCLQLCDRASRAKAPRPARSRELAPAARRPGTAAAAPVWARRPQERERVTHLARARDDSTATATTGAGGSRTRASLCVLSPRAQSRVRRAHPLPPPLLQALVLQWPAPGEDHHPPSPPSAGLADKQPRSSRARSSRRHPLMRHDPTADRPGLRAPAGPCNAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I2</accession>
    <name>A0A6A6P0I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_321649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0I2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="32466" checksum="A999BEAF8E746665" modified="2020-06-17" version="1">MGGGGRWWGEPAAFVSPGPRDPGVEGGSCWLLGNGLQVSSSEEGRAAGPSLEVVPVVGRASERRWLQQQLASVGSHVAGQVGTATVRDVNGWRHSLLHCQYAPAAASGRLRTFFIIFPPLSLPLSFQRIRPDASSLAAILFCVTVRPPLCPFRTLPLASPSYNPHPAAFTSRGFPCFLPVIPYFLSVDPQFLPRCPGTLPACRFPSGANAGIHSPSNTSFLDPFEALPSHSKKKNKFYFRFCSSSAFSRLDPPNSHLLLSSDLAFNPDDEASPSKPLHLTSLFTPYQPPHLHFLRPSSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I8</accession>
    <name>A0A6A6P0I8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2-16 kDa</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">E2 ubiquitin-conjugating enzyme 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_285877</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0I8"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000010">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-16 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="147" mass="16565" checksum="5865B7D81E73CD0D" modified="2020-06-17" version="1">MALKRINKELTDLGRDPPSSCSAGPIGDDLFHWQATIMGPGESPYSGGVFFLAIHFPTDYPFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRRRYEATAREWTRKYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0N8</accession>
    <name>A0A6A6P0N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biogenesis of lysosome-related organelles complex 1 subunit KXD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">KxDL homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_285971</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the KXD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0N8"/>
    <dbReference type="OrthoDB" id="4089816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051390">
        <property type="entry name" value="BLOC-1_subunit_KXD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019371">
        <property type="entry name" value="KxDL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37787">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT KXD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37787:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT KXD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10241">
        <property type="entry name" value="KxDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="KxDL" evidence="9">
        <location>
            <begin position="102"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="199" mass="21187" checksum="C3EDA1BC91ACD156" modified="2020-06-17" version="1">MSSQQYSYYATGSQPVSVPQKPGQFQPSLYGPPAQGAAYGASPPEAPDSSVASGTTGGPTSYGEPTATHASTSSYAGSASEYASSESTAGSVDLLDYMSDRVSGAYDPVPLDRSLAKQAQTSGQLNAKTQEIARLRALAEQRLAAVQADFSQGMKTAKGVERDLQWTQRKVNDINARAQRKYPEQYRAASQRYPAPVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1K1</accession>
    <name>A0A6A6P1K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP-2 complex subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_16242</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1K1"/>
    <dbReference type="OrthoDB" id="28053at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000020">
        <property type="entry name" value="AP-2 complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017104">
        <property type="entry name" value="AP2_complex_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003164">
        <property type="entry name" value="Clathrin_a-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02296">
        <property type="entry name" value="Alpha_adaptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037091">
        <property type="entry name" value="AP2_complex_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0168">Coated pit</keyword>
    <keyword evidence="3 7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="10">
        <location>
            <begin position="732"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="659"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="659"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="23"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="68"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="971" mass="108693" checksum="7A2B3F6BE286D3E7" modified="2020-06-17" version="1">MASAPGGGLFSRSGGSNSASTMRGLVSFIADLRNARARELEEKRINKEKANIRQKFKEGNLNGYQKKKYVCKLLYIYILGWNVDFGHLEAVNLVSASKYSEKQIGYLAVTLFLHEQHELLHLVVNSIRKDLMDHNELNNCLALHAIANVGGREMGEALSADVHRLLISPTSKAFVKKKAALTLLRLYRKYPAIVQQEWAERIISLMDDPDMGVALSVTSLVMALVQDQPDQYKGSYVKSAHRLKKIVVDNECAQDYYYYKVPCPWIQVKLLRLLQYYPPSEDTHVRDLIRQSLQRIMDMAMDMPKNVQQNNAQYAVMFEAINLTIHLDTEQQLMAQIGTRLGKFIQSRETNIRYLGLEAMTHLAARSEILDPIKKHQNIIIGALRDRDISVRRQGLDLLYSMCDSTNAQPIVHELLKYLQTADYAIREEMVLKVAILTEKYATDVQWYVDISLRLIAMAGDHVSDEVWQRVIQIVTNNEELQVYAATNILQYVKADHCHETLIKIGGYLLGEFGHLIADTEGCAPIQQFMALQTKLGNCSTGTRAIILSCFIKFVNLFPEIKQHLLQTFRIYSHTLDSELQQRACEYLALASQPTDDLLRTVCDEMPPFPERASALLSRLHQKHAGTSDKRTWVVGGKDANADPKEFNLVQNTGLRRSFTNGSMTAQPARSNTSNSLGAIKETNGAPPQNGSAANDLQGLDTSVDTQKTLKSAAPNFASAAHLSPDWEPGYNRMLLSSSGVLYEDAQIQVGLRTEYRAALGCVILYFTNKSSTTIGSFTTTLDNRAPDALKTDIKGLPETSIPPDAQTSQMIMFEAKGIFSDPPTMRISYLAGALQALTLQLPVALHKYMDATSLGADDFFRRWRQIGGEPREAQRIFGLKGSGRKTNISTTRKVVEGFKWGVLDGVDQNAKNVVGAAVLHTTESKYGCLLRLEPNFETNMYRLTIRATDESVPPVLMKFMEEQLSLGDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P285</accession>
    <name>A0A6A6P285_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_22841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P285"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17578" checksum="428D7F0583A0F2CF" modified="2020-06-17" version="1">MAALVSTNESYVVNPYCSAKYMRRLSRNGFVPYPAYKNRREVMAINKEKESNDSCKCTLFVAKPALAEPATCRTPSKGTSTTRIPKHRAVKPTKKNLCESPWKTGSHRGKTCPSPSSKHMIEDNRRYYEWFSQVWPRAPESGKSLAAGGRRQHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P296</accession>
    <name>A0A6A6P296_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_411497</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P296"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="44"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="420" mass="47411" checksum="6B5AB7DB2927BE09" modified="2020-06-17" version="1">MANDTSQPPQAVYIPEIDLEDFEDYTIGGYHPIVIGDTFQHGRYHVVHKLGFGGYSTIWLADDKKSERYVSLKVLVAGESSKSTEGEILRLLHSVDSMHPGQRFIPRLLDEFSFEGPNGRHTCLVREAAGCSIAASKEDSVNFMFPIETARSIAAQLIMGVSNFLLRGPDLDKLSPDELYKRYRLDKVPVTRIDGAAVEPHAPPYAVYPMHINMAADKLVDPIVTISDYGTSFILPTNCSPELHTPPLFLPPEDFFHEPITLAADIWTLGVNLYGILGERPLFETLSGDRDDIFADTISTLGRPPARWWDSWGNRKEFFEPDGSWIRNVKRIYTPVFRPLHQRMWDMGRGKTTETCEWDVEGGEMQALEELLRAMLAFEPAERPTAKQLMASEYMVKWAMPAWQRQLGRAKDVETGSSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2C9</accession>
    <name>A0A6A6P2C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import inner membrane translocase subunit TIM16</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit tim16</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">Presequence translocated-associated motor subunit PAM16</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_363568</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM16/PAM16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2C9"/>
    <dbReference type="OrthoDB" id="10262892at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000006">
        <property type="entry name" value="Import inner membrane translocase subunit TIM16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005341">
        <property type="entry name" value="Tim16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12388">
        <property type="entry name" value="MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12388:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03656">
        <property type="entry name" value="Pam16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2457984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19098" checksum="7506EA2D1E4AF169" modified="2020-06-17" version="1">MAHRIITQVVLTGSRVFGRAFAEAWKQAAASQKHKAAELKRPGGAARAAATSSAGLTMDEACKILNVAPPKGGKADMDHVYERFKKLFDLNEPKRGGSFYLQSKILRARERIEAEVRAAEEEATHERYRKGDYWDGPKIYKDKPRPIGRGGLAAAKAISGQDYYRPKRGRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2P8</accession>
    <name>A0A6A6P2P8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1511"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="955"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1137"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1209"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1242"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1281"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1327"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1350"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1424"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1454"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1535"/>
            <end position="1544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1544" mass="162395" checksum="08A861236DF08175" modified="2020-06-17" version="1">MPALTYLPASPAAAASLRQGDTSTPPSEGDSTAAVRGASSLKHALPPLRSARPTSSFPPQSPPTPETTPPGTSDSAAPPTTTATASPAAAMATTTTTTAAPAGMRSARPKRLSGAGTVPQRSNSYTSRADSFKTAREDWDSEDDDEEVGRDAVGGEEGDDRSPHFSSAERFAPPGAFPSSVGGGAGGRHGRAAGFRASSPAAMLPPSPPLPRHSWFGDAGYDYLEGPDDDDDDATPTATGEVTPRPRKSRSAAGVDGAADEGDGDSADDGSGGERDAGRMRHVTVRRRRPRQQTHPAPNGLRTSPDVDDMKRAYSLRERAEKMHREPHKPSPSKKHKDQLQPQQHHRTQRRQRTPPSDQFDPEVGWPHETMRDRDAKRLSAASNASTSSAVVEAALVFADGAPPSRRQTLRHVRKNQALRSESGGSISSLGGITVTSTVGPSSPVAGERKGLPDSSLASSPSTTAPTAATTTADSTPTPRRQPRLVHKRSPIPDRSHHRGASGSSLDAAAAAAPGQRNVSSPAAFPAVALTYGENDAPGSGSGSARGTPRGLRDDEAFERPPQPPPKDYPPLAGARGDGARGLPSVARRFADAQQLGAAGGRGRTGESPRRAVSLGGGTAPPTRFREPEQKVLPRFLPASAVPQFSRGAPSSRWTPEVPGKAEEGVAAGGGGGGVGRSASAGSRGESFRTAGEGKGEERKRQEHDREREASSKVEQPPRVSESKGEDMNDGSRPVMREQVREPASAVLVSSPPRVNDDPDDRRARQESTSPPSSQPANQVPPSFSPRSPRRASTDSDMHSYHRLRPASIDTARTVALSTPGAAPVTGDAPSSAARLLRAHTPHSTTSSRFADTPELLEATAVTFVPYSASEHVTLVRRNTLPLAKAESNGGGAFERGDVELEVEEDEHAPAGPVVAVCAATPPPPQPPPLPKEQHQREQEQARPEGHDEERKADASAAAPPAPPVFKVIPPTPCEEDDDDEERHQLGGSARPRGEMRDGGAARPHPASRRRSVLQRARGVAAGIRLDVSRGWRRSGVARAVSARRRGPTRYYYYGAEGAGADGSDEEEVEDPTGGRLHPEWRPRWAARDEDEYFSDEDDEVDEEEALLPRAGDGEDADVDVDGLRGGPRLPLGGDTSDVRGESEERAQKGRWRAVVGEGLGKRLEGLGKAKLPGTAREKTRRVLGRGKRWGGGKEKGSRGGRGGGLDGAADEDTEGEGELDDGQRRGGRRVRETTVDIDEYVIERVRHADDDDHHHHHRYHRLEDDKEDPALAPSSANAVPKDKDENDKNAQKADMSAASVGGSQPATGPGSVASEPTTAIHDDDVPAPAADAPGAAQAGRDARRDSARDSAGSQNPTTAAAAAKPAATKPAAQAPQLPPIETDVALSPKAGGGGGDDDHRQDGALGEPIPGLLLTSPTMPTGPASTSPLELPASPPPPPQSSGGDDGERGADPLSPATAGPPLAPSATAPTPTSARRPGGGLHGRRISLPGNWVLVGPRTWMAELERARAERRGRRMRDSGISGPVLQRPEMGWSREEWGRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3L5</accession>
    <name>A0A6A6P3L5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_258296</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3L5"/>
    <dbReference type="OrthoDB" id="347657at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05581">
        <property type="entry name" value="STKc_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000128">
        <property type="entry name" value="Serine/threonine-protein kinase ksg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039046">
        <property type="entry name" value="PDPK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="233"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="575"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="617"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="794"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="619"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="794"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="833"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="854"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="871" mass="92662" checksum="8A1CDC81BC1E3633" modified="2020-06-17" version="1" fragment="single">PQPPPPSQYSPAAAPSSSLPPPPSYLGAPSPPNTTPTSSRSPGAATRPMSGLYNHLANTPPDNNYRYRDDAPMLSQPGPGAVNLSRNRSTSSRRSTHAAMQAGVPVRESSRPDRQYEYGGPPPPPQPQPQQLQQMHGGNGPAPPRRSSRRVHQGSASVSGQGGTPAPVGGGGGMVAPAAVAPPAGSPYALENGPPASSEEWKDKGAAVGMRSEVDPATGNRVQRVVKKGVKDFNFGRTLGEGSYSTVLAATDRQTLREYAIKVLDKRHIIKEKKVKYVNIEKDTLNRLTEHPGIVRLYYTFQDERSLYFVLDLAAGGELLGVLKRLGSFDEECTRFYAAQILDAVEYMHSKGIIHRDLKPENVLLDSNMHVKITDFGTAKILDLKPRPGQPPQQQQQQQQQQNGGGPMGTPGTTPTAGPPAADPGDPLDGADSDRANSFVGTAEYVSPELLTSKSACKASDLWAFGCIVYQLLAGRPPFKAANEYQTFQKIVALDYTFPEGFPAVARDLVERLLVLDPAKRLPVEHVKNHRFFEGVRWGRELWVKGSAPRLRAYVPPKGELIRLNGEFCAAGEASDLSSGPLRPQPRVITELPPPSQLDIDWSPVLTRSNERILKLGNLTVTSRPPTQGGNSSAARSGGDLSISGEAGEAGGGAAGAAAAPPPPPPVVVDAPKKFAARFFGGGNTLKRRQRLVMVTSSARLILAAAGGDEKKAKMEVSLLGQGVGWRSFRDAKGVVGWIVDTKDKHLVFEDAKASSTPVDPEASRYTAAEWLDALDRARDMALSQQGAYAYSSASGADNGVSAGPGPTGSSISSPASTLNGAVMNGADASAIDGRERGERDRERGGADAESLKGRKRFSKRHSKNGLAAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3W7</accession>
    <name>A0A6A6P3W7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3W7"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000096">
        <property type="entry name" value="DnaJ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="761"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="802"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1062" mass="115287" checksum="2ACB33C520CFA976" modified="2020-06-17" version="1">MVKADPTRNYYADLEISSNADTEEIKKQFRKLAMKHHPDRNPGREMDCIPKFQAIQAAHEVLTDPEQRYKYDAERRKRGYGSPAYGRPFASQRTTSNNAPFPPPPQRTRPSARPTATDSRYTSSGADRFSQFPRPPPPPPDEDPMNKFTAWGRMHSKAKPQQSQQRPPPPRPNAHRTSYAGGYPYAGAHSDQEDIHRTKPTANTSNAYASDSSAKGKPGVSRSNTTRSPKRPGFNPAAPGEGDEPPSRGASAYFTTSRFAQAPPEVPRDETPPQRGPAPTARKPDPSAYPEFDRRKPMPYGSTGGERTSLYSDNLRRSMSQRNPQKPGDSTGTSPASSHPSHEPRSGRHRSMSPPSRMYSPADQPNIGGSRTAPRPTNRGGNASRPFNLDYSDSDEEEDSPPSRRAGANGPKVPHDIKARPKAQPSPSWANGRASKNDQRQENVFQAAADQKRSQQQDGTSQQQRHSTMYGRNFSSSSIPRFKWSRDWVDKSRRRSDGKKRLPDWAYPATVKPPTPGIPIDTEEDTSQAPALKDPLATTAGLLPRKEPIQHGLQPGKHLRPSLFSTAEKTDSANETPNISFTMPLNHGPSAGPHRPDMKSKSEESISMKFSPNEWNGVFNGSSGYFAGESPASRNGPRARVSPVRGRAQGGATVSTPTSANASTNNVNSPQQTSNDFGTQATSAGGSSNGKITVKLRYKFGVQLVDSRSTAPPPPPPPQGFDASEWAEKLKESSFLYNPSDKPPSPVKRPTSKGRATSRSAPKPTTMPKPATVTEDVDESDLPGDSPTSEDSNRMDIDTDIPAATTAGAKPTTENGPKKGPRNVSAPTGRPEWRDAAKKASQSSRGAQQPEPRGSTGAAPAVPSGAGDQREASGGQFTGLNDLSNVAPFAPSREGLKDMRDLDSTLPFESRAGTATTNGVSAGATEDDDDLTEERQKLPSPPKAPSPPSRLSQQNWQQYLARFQLYATKWHEFNAKIVTHFAARVTDDDKLFGAAAGNSRGACLAAVGETTSGVGFSAVMRNMRRDEMVRVHWNVASEMHAEALKKFGQVRERMRKGGLPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4D8</accession>
    <name>A0A6A6P4D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_301777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4D8"/>
    <dbReference type="OrthoDB" id="1661054at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="544" mass="57366" checksum="05EFB5DCA9C9E181" modified="2020-06-17" version="1">MSGDPLYDLLAPALQQHQQQREQDEDSQHQHGAPSPAAADAAVTSAYLARLTTLPLEALTTTEPQSLAQSAQSSMRSLQALSKRSHKAMMTSAERLSSLRESLPALAASTGELHAALPPLESAATSFAAKHGRGTGGRGLSQGDGVNSNAILDRRRRAMLLSRNIDRVADILELPTLLSSAISTAASAAGPSSSQQQQQQPAQSGSPAATTTTTAATNYASALDLHAHIRRLASLYPNLTLVRALAAAADREMRAMTTQLVTALQSPSLKLAAAMRTVGWLRRSGMGMGMGAGVSVGGGGSGEGALGALLLVCRLANLVVTLEALAPLRELADQETARRDDKKGKDGGDQRDRWAGGQQTERYLKRYIEIFREQSFAIVSMYRSIFPAALPTPSTTTSSTTNPQSSASSDEYLNPLLPLPSPLAAFPLHLVDLLASTLRTYLPNVRDRSSRDSLLTQVLYCAGSLGRLGGDFGLVLAMLEEQDGGVDGGTEDDDGDEDEEEWVEIIKKHRVQASRLELLASGVGTGRNVSGGAGGAREAVGVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4G2</accession>
    <name>A0A6A6P4G2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_339100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4G2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="18787" checksum="A93553B4A67716F8" modified="2020-06-17" version="1">MPAGAARRLLEPLEICQVDGRTGIPQGRSGGMAPCLLRTGPDGRTAVISGGSCTLIRTDMYDQGSAGSAEGHLLSPSSQHIRTGRREMERFRKYRYFHLEDCSINFCRAPRSSQKWSRSTLRRCSRSLRYQRRLLSQRVRLAIPDKGFCRSDEPGQELISGIPFQSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4L9</accession>
    <name>A0A6A6P4L9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_362935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4L9"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="25554" checksum="584A12B208971F34" modified="2020-06-17" version="1">MPSPNSRSRSPPRRRRDHANEDTRGDERAPSRRPRSMGGFRWKEKPRRDEDGGQNEQSERGSGSGGRGYYGRERERERERSPRRESDRYEERRQDGYRDRGAREDRRDRDRDRDRERRDRKERKEEKRKEKPVLTSGGEEMIRVTVNDRLGTKAQIPCFASDNIGDFKKLVAAQIGRKPHEIMLKRQGQRPFKDALSLADYEISNGVQLDLEIDTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4R2</accession>
    <name>A0A6A6P4R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homocysteine S-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_341268</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4R2"/>
    <dbReference type="OrthoDB" id="261426at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="entry name" value="Homocysteine-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11103">
        <property type="entry name" value="SLR1189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11103:SF18">
        <property type="entry name" value="SLR1189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="Homocysteine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025450244" evidence="4">
        <location>
            <begin position="17"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Hcy-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16419" checksum="3ED55B0E66C1730E" modified="2020-06-17" version="1">MLCLMTAGSLAEAVAAVRLARRVGLPVCVSFTVETDGRLPTGVSLGEAIAKVDALTGAYAAYFGVNCAHPEHFMPALRALARDGVRRRVASVRANASAKSHEELDRSEVLERGDPAELGRLHRELKEVLPWVKVLGGCCGTDAEHVGEIADCVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Y6</accession>
    <name>A0A6A6P4Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin complex subunit 54-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_339668</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Y6"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21121">
        <property type="entry name" value="Nup49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="43725" checksum="7EAB83E5D2655DE8" modified="2020-06-17" version="1">MSAFSGGGAGGGGGGVFGGAPSQSGSGGGLLGAAPSSQPGATGGGLFGGASSQSAAGGGLFGGSTGSQNQQQNTGMTSGFGGPSLFGGNAQQTPGQQSSGGIFGNLSQSKPSTAPSLFAPSSQQQQPSLFGATSNIPPSSRPMFAGPLPGAITPGQNQPLQQPVPGVNIDVSQMRSTTRFNDLHSHLQEQIMQIDSLITAQTQAAAQVSAFLPSHGEALKFLPNDADYLTQRVDAVELALDNDSTAIAHQKSTLTSAARDASRVFRAAENLKLPPQFHYHIAGSIASGSPTAGNSAAPRVNAPALEGDDDDDDPLAPVDLIPFFSTCADELRERLRVYESQLSEVGAHMSAIEARVLAETEAALLRAGAQATGADGVEGSKDEQIRVLYAVLRDFEAAILKVAGHVGVAREGVLEVTGMLGGPPPASRLGSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Z4</accession>
    <name>A0A6A6P4Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitotic-spindle organizing protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_283246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the gamma-tubulin complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Spindle pole body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MOZART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Z4"/>
    <dbReference type="OrthoDB" id="48571at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000931">
        <property type="term" value="C:gamma-tubulin ring complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031021">
        <property type="term" value="C:interphase microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033566">
        <property type="term" value="P:gamma-tubulin complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051415">
        <property type="term" value="P:microtubule nucleation by interphase microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022214">
        <property type="entry name" value="MZT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28520">
        <property type="entry name" value="MITOTIC-SPINDLE ORGANIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28520:SF2">
        <property type="entry name" value="MITOTIC-SPINDLE ORGANIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12554">
        <property type="entry name" value="MOZART1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="8782" checksum="C9001557B2DAFD79" modified="2020-06-17" version="1">MPPASGEPDKRQAAREVIDILHEIATLLNTNLNRQQLSYCVSLIENGVNPEALAAVIKNLREQYPEPLDAADSDERQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P500</accession>
    <name>A0A6A6P500_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_339124</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P500"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="8">
        <location>
            <begin position="67"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="9">
        <location>
            <begin position="209"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="28175" checksum="94699592D285280E" modified="2020-06-17" version="1">MRFPTPLIRTFASPARKMTSDSTSKLIFAPSSDPATRQAAQFTKGSLDLADLAPDPFQQFAAWFAHAHACGVPQAEACTLSTAQLPSGRVSARVLYLKELEARSSGGFVVYSNTGTSRKAADLRTNRWAALTFWWRELERQVRVEGTVEMLAPEESQVYFDTRIRGSRIGAWASEQSTVLRGREELEGRVKDAKQKFEGQESIPVPDHWGGLRVVPESVEFWQGRHSRLHDRFLYTKGSGKSEWTIERLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6F0</accession>
    <name>A0A6A6P6F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_270891</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6F0"/>
    <dbReference type="OrthoDB" id="3168162at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000059">
        <property type="entry name" value="Serine palmitoyl CoA transferase subunit LcbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="124"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="510" mass="56974" checksum="B8CF96F79C213263" modified="2020-06-17" version="1" fragment="single">MDLHELQAGVLRLLDEGWMQFQKVPGSAIVLRYIKSSYQNDPMRSVVELLLFLFALRYMLAPKYSTQKPDRIKLTEEEVDELVEDWTPEPLVGKPTQLEELDNEKSPIITGPTGPKVKLTNGRTVTNLGSYNFYNFVADETIREKAIDTLRTYGVGPCGPPNFYGTQDVHMRTEANIASHLGTAACIVYAQAFSTISSVIPAFSKRGDIIVADKAVNYPIRKGLQISRSTIRWFEHNDMADLERVLAQIVKENAKKPLTRRFIITEGLFENTGEVTNLPKLVELKLRYKFRIILDESYSYGVLGRTGRGLTEHQNVDPHEVDMIIGSLSGPLIAGGGFCAGSREVVDHQRITAAAYTFSAALPAMLATTASETLRILQESPEILQALRENVKAMRAQLDPRSDWVRCTSAPENPVLLLVLKAEVVAQKKYSREDQEYLLQDVVDECLANGVLITRLKNMPAPLGQGPRDRTWQPQPALKVCVTTGLSKKEVEKAGIIIRHAITKVVTRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6L3</accession>
    <name>A0A6A6P6L3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_190767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6L3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="19934" checksum="12C0A05EC800A9CB" modified="2020-06-17" version="1">MYSWVCTLPPRCITNTSFIGQRAWIWATACEWLTVRMQLIGLHVLETTPRKELHVGQKANSPINARRRDHFPHYVTDGNTISNISLDERARWFPPQPFLHKGGLPRNSRHPPSHRRAFFLVLGKHVSHRYQKDAIAVGATIGKPANFHSTALKHGRSLLLAIRVSGSCSAKPCKKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T2</accession>
    <name>A0A6A6P6T2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_282257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T2"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="22"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="546" mass="58812" checksum="5043D758D5DF30B2" modified="2020-06-17" version="1">MLPIVDLFYSIHQATYFNATGNFFFFQDIPYAAPPTGNLRFTAPMLPMADRFNVHTGFGGRKCPQAPVPAWSVASSFASQYLSGVPLGQIAIPELDTTPVTPGPQETEDCLYLDVMAPKDALQSAVGQPTAVFSPPKPGAPVLVWIHGGSYTTGSKDFYGDLSGLYPRLDVAGIEKMVFVSINYRLGAFGFLAGSTVQMGGVANAGLLDQRMALEWVRQNIFRFGGDPNRITVMGESAGAGSVMFQLAAYGGHFGTPFQQAIIQSPGYIDISTREAQDETFNTFLELAGADSLQSLRALPSEDLMRANSLQVNTKSIFAFPPFGPAVDGIFAPTMPDHGLLNSPPTFDTGIPVMASRVSFEGLLFTQPDAARYDDSLHDFMRQLLPGITESAIRYVTSTLYPADYGRAGELRYADPVQRAARILSEAGFDCAARDLGIALQGGAGLHAYEFAVPPALHAYDVPYTFWGGSEVDVPGPAGVNGTVANAIQMALASFVAEGRPRDMPAYGPERKCTRFSDEGITVGTDGAVDRRCGFWQSRAYREEWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6X2</accession>
    <name>A0A6A6P6X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_338653</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6X2"/>
    <dbReference type="OrthoDB" id="9971853at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000131">
        <property type="entry name" value="Glycoside hydrolase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000106">
        <property type="entry name" value="Glycosyl hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="5">
        <location>
            <begin position="118"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="6">
        <location>
            <begin position="712"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="620"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="622"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="857" mass="95847" checksum="FBAF047EF461CBA4" modified="2020-06-17" version="1">MVIVHLRQTRRLVASRLSAHLARLTGSSPRKSKPRRRLRKRRPLVNMAPPVMRLRVDGTRFRDQQGREVTIHGINVAGDAKLPAHPDMPSHVTEGFFDGDDISFVGRPFTVDDAHIHFARLKKFGYNTIRYIFTWEAIEHAGPDKYDEEWIQHTIEVLRVAKDYGFYIFMDPHQDVWSRFSGGSGAPMWTLYACGLNPRAFDVTEAAIVHNLYPQPENFPKMIWTTNYTRLVCQTVWTLFFAGRDFAPRAIIDGKNIQDYLQEHFLSACGHLARRIHEAGDLEGRVVVGWENINEPNRGLVGYQDLTAIPKEQKLQKGTSPTAWQAMLLGSGRACEVETWDFGGMGPFKSGSVLVDPAGTMAWLPKDYDDSRYGWKRDPGWRLGECLWAQHGVWDPASDEILRKDYFAKRPGTDDTVTYEYFTNHWFMDYWRRHSRMVKSVFPDAIMFCEPPVLEIPPSIKGGPDDDPNMVFSPHYYDGVTLITKKWNRIWNVDVFGILRGKYLTPAFAVKIGETAIRNCLRDQLSAIRQEGLDYMGNHPCVFTEIGIPYDMDDKYAYKTGDYTSQALAMDANHFAIEGSLINGFTLWAYVAGNNHYWGDNWNGEDLSIFSRDDRPPPLSSAFLSANPSRTSLDPASPSYSQSHLSESASISPSTLKRTLTAENMTASASSSNSAVPRAINGASGTPAQAQTPLSQSLILKAGFRAAEAYIRPTPIATHGDVTAYGFDLRNCTFTLNLVAPSATPDGAPTEVFLPEWHFPPSSGGRVSVEVSGGKWVVESVEVNEGEGEREEGGEDGGSDAVVVQKLRWWHAEGDQWVKVKGVVRKLGGAGVDAEGEEVEEGYLEQCQQLPRGCGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7D5</accession>
    <name>A0A6A6P7D5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_316398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7D5"/>
    <dbReference type="OrthoDB" id="9999821at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="194"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="458"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="836"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="927" mass="101723" checksum="0D803078E7D15521" modified="2020-06-17" version="1">MVVTLDGKSSYQTPPTLRLFAQPMDLLPPPPAKIGGAGGGGSGGGGGGGGGDSKNGELRPEWVDPLAGQPTVGRDGRTVFVRPVDMLEPGMDLSGEEDPEAVDGLFETTRSAPVTGGSSTGSAAGRPAPSRVRRRDGERLGKYREVRGARLHAERGVTFWRFGLEVELTAAQARIAYRINRGPAVGFWVPARGQSMHVMFHSCNGFSLSVDPDQFCGPDPLWRDVLGTHQTRPFHVMVGGGDQIYMDAATKYTKDFRRWCENKSWKDKMDEPFSAEMQDELEEFYLERYAMWFSQGLFGMANGQIPMVNIWDDHDILDGFGSYPDNVMSCPVFTGVGAVAFKYYMLFQHQSLPTEGERDEPSWLLGAHRGPYIDELSRSVFMSFGGGVKFLGLDCRTERMHDEVLSQETYDRVFDRCRREVVKGETRHLIVLLGVPIAYPRLNFLENVLTSRIMDPIKALGRSGALGGFVNKFDGGVEILDDLNDHWTARHHKHERNWLIQELQELAADKSVRVTILSGDVHLAAVGQFYTNRALGVAKDRDHRYMPNIISSAIVNSPPPDMMADLINKRNKVHHLDDETDEDMIALFDQDVDGKKRNNTHLLPRRNWCAIREYIPGATPPPYSRSRSRSPSPYEAARPRRPSNSSRRPSITRSLSFGRRGSFSGMRPGNILRRLSRGGGGGGGDRRAEGPPVSYYNRDAAGHQQHQPPPPPPPGPFQRRPTISGTPGGGGGRKYFGGGGGDGAPSAAAARAPYVDLEHGLDVALNVEQDASDPTGITKPYRLLVPALRYDGPRDANPVARRSRGRWGGLLGRMRRRGLLDGKRDDEGEDGGGEAAGSESPSESEAETPAAAPRAGWRRGAEPSGAKPSRRDGRAGGYGEEAPPPPRAPPRRSERYGARAYEDESVGSATPPLPPLEKKRPGWMIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L8</accession>
    <name>A0A6A6P7L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I 3-dehydroquinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7L8"/>
    <dbReference type="OrthoDB" id="4415835at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF27">
        <property type="entry name" value="QUINATE REPRESSOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH C-terminal" evidence="1">
        <location>
            <begin position="801"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="842" mass="92857" checksum="EB15160E690C5E4D" modified="2020-06-17" version="1">MSGAPYRPPARLPRSFEPEASVVLIGIRGTGKSTLAVFASSAFQWRLVDADYAFHEATGLTHAEYKQRHGAHDYRARQLGVLQSVLHANPKRCVLVCGSSSGALEKTGQELLRDYARSHPVVYVVRDPKSLQGYLKDWQLDRITTILNHSGSVFRSCSNFEFYNLTEPKVNAEPSALRPALSAPTFLTLNHLERHFLKFITLVTSGAGIPSLESAYPLSQIRPEFRRYTYGMAVPLSAFVNHDLDVEELESGADVFELIVDDLTSPAKFEQFSCSRADQISDAFSRIRRGIIVPLLYHVRPGLAMDSEEAKTIYLDLIFHGLRLAPEYMSLDLSLDDNTFNEIVRMKGSTRIIGHLFVRGDHPPPWDSPSWIRSYERAKWLGCDIVRFLRPAFALEDNYAAQRFRDTVSNLPSPRPPVIAYNTGEMGRFSACFNPVLVPVTHPILQALEAPKPIIASVGGGHERSVPPPDVLRTFVRPCVTAASCTNALFSAFVYSPLRFYVVGDAAHKNPCPPMHEVAFQSCGMPHTCSWHQERNIEKLKELAGGSYFGGFSINDSLAIDTTSLSNLWSPHAKAVGAIDTIVPIRASSRASEPLGDLLDLMDTRNQPGPVKALYGDNTTWLGVRACIRRGLSPANAVTSRTSALIVGAGSTARAAAYAVLQLGVKNLFILNKHTEDSEGVVAHFQRLSSTFSHETNGDSTKGTNPLGSTAEFHILESWDTPWPVDFRQPTIIVSCISSSDCLATLLPSQWLKSATGAVVLDATEYTPPSSSVSVLAKQIQSEAHRGYISMGASDLMPEVGFAQFELFTGRRAPRNVMRREVRQRYIEIERACSDGNSYPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U3</accession>
    <name>A0A6A6P7U3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_281061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7U3"/>
    <dbReference type="OrthoDB" id="3784695at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="12093" checksum="212A398C610835AC" modified="2020-06-17" version="1" fragment="single">MPLDTVTTTFFISNLHCPSCVAGIEAALKALHPPPRSISHSILTHQIVARHSSELPVQAIREALDLAGFEIHSVFEEGEAQQDDRPKPTGIRHFGTEWESSLERAVARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P851</accession>
    <name>A0A6A6P851_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_299548</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P851"/>
    <dbReference type="OrthoDB" id="18574at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090422">
        <property type="term" value="F:thiamine pyrophosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000011">
        <property type="entry name" value="Mitochondrial thiamine pyrophosphate carrier 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="14"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="125"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="221"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="329" mass="34852" checksum="06757819A02711A4" modified="2020-06-17" version="1">MASDGSVKALKDEGTPTQVAAAGAIAGLVSRFVIAPLDVIKIRLQLQTHSLSDPLSVASAQGGPIYKGTFGTLKHILRDEGITAFWKGNIPAEFLYLSYGSVQFLTYRRTSAFLSSLPPPLGPPPEPFLSFAAGALAGSVATSATYPLDLLRTRFAAQGRDRYYAGLRHAARSISAHEGARGWFAGVGAAVVQIVPYMGLFFAAYEGLKPALAGAGAPLQALGSGDAVAGTVASVFAKTAVFPLDTVRKRLQVQGPSRGAYVHRNIPIYQGVYRTVRSILQREGPRGLYRGLSVSLLKAAPASAVTMWTYERAVGAMVLMERKIADIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8B0</accession>
    <name>A0A6A6P8B0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_337351</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8B0"/>
    <dbReference type="OrthoDB" id="3942380at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="13865" checksum="1989BEDBEB910393" modified="2020-06-17" version="1">MSTEGSIAAPNASKPQAVGMRKNGKQWHQPKSAFRPKAGLTSYAKRTEERKALAATRTKEREMKEEKEAERQRRIQAIKDKREAKAEKERYAKMAEKMHKKRVERLKRREKRNKMLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8F7</accession>
    <name>A0A6A6P8F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_281071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8F7"/>
    <dbReference type="OrthoDB" id="1097733at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="117"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="268"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="375" mass="40084" checksum="A63CB1FCA0219B2D" modified="2020-06-17" version="1">MMEYAQYQQPHHNHAQPHLQGAYNTSPQSGGPGGASITSPNQQPQMHPQHSQTSPILPSQGHNYPPQQAANAGGHPVHQQMGYGAQGYGVPTMYPPQMSVTQAAAMATASASGQPYYPMGDQALQGQLSQDPRASPRMGGHQQKPESRGGPRSPTQVSGPMNQPPLASQVPMSANQSMQPRRMSQSMSSPAVQQPQPVMNHNAPRTSVPPQMAPQAPQVQHQQRSSEVVADGAVESPLYVNAKQFHRILKRRLARQKLEDALRLTSKGRRPYLHESRHNHAMRRPRGPGGRFLTAEEVAAMNKKEGDDGGNKENSDAAAKSGLLGQTSGTKRKSGAGTGTPAKKAKTGGGAVPVQRPSTSDDSEEDEDDDADDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8P5</accession>
    <name>A0A6A6P8P5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_376984</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8P5"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="5">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="288" mass="31464" checksum="7A506AF0F9136D1B" modified="2020-06-17" version="1">MADRYSFSLTTFSPSGKLVQIEYALNAVNQGVTSLGIKATNGIVLATEKKSSSPLIDPQSSSKVQLVTPNIGMVYSGMGPDYRILVDRARKVAHTNYKRIYNEYPPTRILVQDVARVMQEATQSGGVRPYGVSLLIAGWDDGVEPQGEMTSGDRMEEEEDSDEKEEQKKKAKGKTGGILKGGPSLYQVDPSGSYFPWKATAIGKSATSAKTFLEKRYMEGLELEDAIHIALLTLKETIEGEMNGETVEIGIVGPPEDRLLGYEGVEGAVGPRFRKLSSQEVEDYLTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P904</accession>
    <name>A0A6A6P904_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_383962</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P904"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000041">
        <property type="entry name" value="HMG box family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF320">
        <property type="entry name" value="BOX TRANSCRIPTIONAL REGULATOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="119"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="119"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="562"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="357"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="563"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="733" mass="80089" checksum="86136F6C671190FA" modified="2020-06-17" version="1">MSDNVVSKASTSTTGTELNEKGANTPRKPSAALSYGSSGPSAASITHQSQSNDSPTSRDSPRFRELRKRATSVTSKDDDEETGAPDDSPAHTRAGSGDSASTTNTAATHVCLCQPDPKIPRPRNAFILYRQHHQGSVVARNLGVPNPEISKILGEQWRKEPASVKNEWKMLAEEEKIRHQQQYPEYRYQPRRHGRRTSVDPNAGKTTTVDKYRCSKCGGRSIISAAAPLSLALQSPSSYSQQGSESTLLPLPTPTTSASASSSSRFLPMLNNLSLASPQLRRPHPQDNPPRHSSAGGLHIDTSRDGSIARRYDICGTSPPLSSEFKRRRFNNSSQTPEYISIGRANSTSMGSPASRTNFTAPPNTPHPAAATQLARTSSSWSGPPGQSSPRRSELPERWSRGNSSGSSMPPPPTPRHSVSGPRDAGLTLPPLQSAIALSGASESDRRHGVEIMIMSTQRLPKIKLLGRIAPPFATGGPLGPSTKSQTRGSIVAIEADDMTAAYTLTSWLEDWLNRSGEFTAKVAEGPEVPGQEKDVTLADYLDVVRDWHNRSKIMVDFIFPKPSEESHGEPQKQRETRRCERRADSRMDVDSGKESEKTSEDSEHKKRKGSASIDPPASTPLPVVLIPSYQLHASDAFASRIPITDEYSPADHWQWIATLWRGVVGPDVTIYIKDANSEELARERAVEVKEDCRCLVIRKEKVTDKFDDKTLRRVGFELGEWVRSVGMGAKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P933</accession>
    <name>A0A6A6P933_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P933"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="313"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="360" mass="39215" checksum="D65F3D06DDD6540B" modified="2020-06-17" version="1">MVELYACGFNAFRQIKDSTDLPDIRNFIKIASGHEIKVLFASWNVTIYRIDGKIIHLGTDELEDSQAAKEVTTNPSDIYPVSFFGTEDGVYGAISNLGTLCSYFPPTSIKPSVVCTTSMISRRRDESEIHILQFPNGTAFRLWMMDMSDAAEMGQESKQPYNHAPKHFHLQGQATQLCAGTTFFVLLTESGQVWTWGDARHRQRLARPLADSSVSRERGDVPADEPGHVGALDGVPINKIAACGSLAGAVSRDRDLYVWGDQGPQASKSESEARRLSVMDEEGDVKLSTIDDEVDILDVGIGYGHIIAVVEGGRVFAAGEAGNGQLGLGENIPEFVKDWTEVESLKGLQAEGVTCGPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P936</accession>
    <name>A0A6A6P936_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_166386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P936"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="239" mass="25992" checksum="09596A1529246797" modified="2020-06-17" version="1">MPCYFWIGGVEKTDCSTEQRGRHCALLPTWSRAASRQQNFGCRRGIAAECKSAARVYWGVLVRHASGEPGAGLTAMVAGRRRLRRASSDPIPPLGGFSSCQRATVPRRNAVWRRGRRSAACRLFSDLGRTIKGVLLQGGVAPARGSFRTSQTGPGGGGVPEAKVLLLSPSPRTPARPLAHRLSPCYVWRVCQTRTLVHSLLAHAHILRSPTPTHVALSIPKQDCSRPSFPLFSDVVFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9C8</accession>
    <name>A0A6A6P9C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_335279</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="11"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9C8"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="16">
        <location>
            <begin position="40"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="17">
        <location>
            <begin position="307"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2460392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="429" mass="44265" checksum="041FB54E13E16636" modified="2020-06-17" version="1">MANQTGRSDSAQERLSQVSGHLSSQKRGRAALLEQHPDDIVVTCALRTPMTKGGRGAFRDTQASDLLHSAFTSLLSRSGIDASLVEDIAVGNVLAPGGGATEFRAAALAAGFPVTTAVKSLNRQCSSGLQACVDIANAIKAGMIDVGVGAGVESMSTQYGPQAVSEFSELLDSVPVAKECKVPMGALSDRMARDKGVSREAQDAFAAHSFQKAERAQKQGLFDAEIAPVTVRLTDPETDEVREVTVSADDGIRAGMTAQSLAKLRPAFPGEDGSGSITAGNASQISDGAAAVLLMKRSTAQRLGQRVVGKFVAASVVGVAPLLMGVGPWKAIPAALAKAGGLDPADVDVFEINEAFASQCLWCCGELGIPEEKVNPKGGAIAFGHPLGMTGARQVSTLLTELRRTGKKVGVTSMCVGTGMGMAAVWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K2</accession>
    <name>A0A6A6P9K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_280971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K2"/>
    <dbReference type="OrthoDB" id="2958217at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="115"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="64740" checksum="50CF7E849F5DEB3F" modified="2020-06-17" version="1">MTPDDPATGYGVPHPSPLPANTASAETHELAEKWILNCLEQHNCSELGTLPPRRSRRGTNGSQSQSQGHSQNQFADADDELFADVVPARLIDLRAFGKDSEDARLIDVQGECGDYVALSYCWGKEPLQKYTTTESRLGSMKKRIVHDDMPRTFRDAFAITRKLGVRYVWIDGICIVQDSNDDWETESAKMGAIYGKAYVTVAADSSTNVHDGCFNQKSRNQIDDIPGLVKVPNVLVSKRTSRLYIYSTMYDLGVGHAASRSPFPIEHGHLSQRGWAFQERLLSPRTLHYTDRRLHWECRQEYLSEDNMRFIKQEPISSVLSSLPNLRVVDILSMWHSGIVMPYSKRHLSRATDRLPALSGLAHLFSRYLSAAYIAGIWSERIADGLAWYRSGTLPPRKLDGPSFTWSSQPTPVVCSTVMGNSRCSLADHSVVLAGQDPFGAVAAARLKMRCRLRRARVWIEPSDGEHLASQTWVKAWMEHDDGGTPAEVSWDCLEESAERERLDWTVFCLLLFKIGRRHTVLLLEQVDVATPQIQKEEERPGPDAGTVFRRRGIAKFRSIADWFNDGHKLSITLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9T3</accession>
    <name>A0A6A6P9T3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_280205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9T3"/>
    <dbReference type="OrthoDB" id="4202871at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="384"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="528" mass="59093" checksum="1394E31FF02CE0AC" modified="2020-06-17" version="1">MSASDHSNATAQSSTYQDSEPESDPPGPWSPPAWRRHGTGWFRASTATSPGQYDSAQEGDITLVPANVPLPASPLKGTPRSSPEPNTEGQENVREGSVQRADVEGEEEDALDRERSVSVPVQDGANSCKYIRFAVRAEVQHRSEPFEAALLYFKEKLEAMTHSRISTFLSVFAAVFSIAIFRLLFQPPSAGLVPDLVKVAGMARSFEPLIHFSENGFMQIADLQETGVAVWDLGESVRTTNMTSAPIITNELDELSDALKTLSRELTKFFTNVNGDVDAILIVMDWAKRELASISSMPSSSFNSVFDNIHTAFCRVGLLEYGGVQTALGKFVSDLFGQTAPQRTKSTLQRTFNEFLDVLEEAINNELTYSTTLFALFDVIEKHFSNLQRTVARETDQQEREEDEMLSSLWTRVIGGNKNRLRKYEKNKQLLRNMREKTIQNKSILVSHNHRLDLLKESLENLRKRLVSPLVRSNESASLSIDEQIRGLDAAHEHLRSIREIQKARVFEKLFSNGNRRLTGSPLEIDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Y2</accession>
    <name>A0A6A6P9Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_171400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Y2"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="116"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="667" mass="75554" checksum="249AA34F5FCFD361" modified="2020-06-17" version="1">MPAASRWKSFSTASDSRILRVFWRIGTLMYLCYLLLWACAAILLLHTRIKTCISLAGQIFQWLNAIVAQRLVYDPLGPLDRSRNETRLLIIQPTTNENALITCNMIRVSLDDEVTYSALSYVWGLGEATKMIQINGAPFFVKPNLLSVLRRLRLDDQVTPVWIDALCINQADIAERSFQVAIMGTIYGKAKMVTAWLGEASGDSNLAFELLQNAWDVSVRNRNSEKIINLVRLPAYENHWRAIQRLISLQYWERVWICQELILSRRALLVSGPLCFSWYNFVDLLHAVVSWPNLPSAGFRKAASDAIRDITFSQAFKLAKVSQSRRRGFVPALFTTLVLGRSRKATDLRDHVYGLLSIATKHHGMQVDYSKDIRQVYKDSTIACLKSASNAKILTACKLLDTTTGMPSWVPNWSYRLREDSYVNPEFSVEDISYPDFTAGGEAFGGFLLEDGDRTLVVDGFILDKVYSTNFPNVEPHEKQVSNDVLHEWWSMWTSFRESSRASKYGDEQKQLLAFARTIVVGKYSRRSEGQPEEFETDSWQSYWRLALKWHPTTHKSPAAFKDIDSVNPAAAVFKMQSLRTRIYAGLLAAPKFFITVGGRMGRGSMQARPGDEVGLILGAPTPFILRPTENNRYLIVGECYVDGIMDGEALEETTRQSASSRRLRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAA9</accession>
    <name>A0A6A6PAA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAA9"/>
    <dbReference type="OrthoDB" id="4363844at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="423" mass="47709" checksum="D37EDFF8C3EEA08D" modified="2020-06-17" version="1">MTDIAKFEQFGLTAFYNAIPVLDNAGDWFQWKQKVNEFIQISAVAEDGATPPIEEEEVQQWRHRQRLYTAMIAVKLTHNAAQRVKASEIHRVQTLLRAVKENFKPEGSGTFVNLQRQYQSLTRERCGSVQALGAEIRRIHAEQLLFDPDCTTQEIGRIFLFMDALGTDYEGFRDHIFRQMNLVNDRDADGNVIKAAPTFDYIESKAIEEEHRKGQLAKQPAERQALPALALIRGPGRKKLIPAPDRKTCRVEIDDIPYCAFCEKPYHAESECFKKNPRLGIQGKHEKGRKTRPGDSNSSRYKPSKRQHASDDEGDEAGGPRDPKKPTFTAMKTTGEDVNAAFKKNVQANTTMLAHTSAMMARKTLPIRDAWIVDSGCAQHVCNSASKVSSSNRYASSSITMNVPNESVDEYVSTESLSKWEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAG5</accession>
    <name>A0A6A6PAG5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Short-chain specific acyl-CoA dehydrogenase mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_279149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAG5"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF15">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE APDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="157"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="265"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="442" mass="48423" checksum="D5FAC905A1F9BB85" modified="2020-06-17" version="1">MQSKPFVPFSEPPWLAGLPSPYYSESHRRWQRVCNEFVTEHLHKYAMDWDLEETVPDHVFSDFAEANMLIPTLPAPLPVEWLKKLGIHDVGGVKVEDWDYIHTAIYADEMARSGLAGPSGSLTVGMSFGVPPIIKFGNEQLQERFLPHLLTCKKRACIAITEPSAGSDVANITTTAGKSDCGKYYIVNGTKKWITNGIWADVSAMAVRTGGPGASGISMLVVPLKGYPGVSMRRIKVAGQVSAGTTFIELDEVKVPVENIIGQEGMGMRYIMTNFNHERLSIAIGATRQARVALSSAFEYVMKREAFGQPLVEQAVVRHRLAKCGAELESLSAWVEQFVYQMTKLPRQVADVELGGLTALAKAHAGRVLNECAQCAVLLFGGNGFTRTGQGEIAERIYREVMGVRIPGGSEDVLLDLAVRQLLKIYQAKTKALGKEQGSPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAI1</accession>
    <name>A0A6A6PAI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_133889</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAI1"/>
    <dbReference type="OrthoDB" id="660759at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="219" mass="24306" checksum="DDC5F781AEE0B34A" modified="2020-06-17" version="1">MASTSFRDSMNSLGWSRRDPDLPVNTSRTTPLLDRLQSYNPFGGGGYVRLPTQENNTAGAPLPAPSRREEEEGWFALSRWDRLLIFGGLNLAALALFVTCFVLMPTGVFALRPRKFAILWTVASMLFLVSWAVIMGPIQYIQHLLSGPRLPFTAAYFGSIALTLYFSLGLHSTVLTLLASIIQLVCLVWYLVSYFPMGSTGLRFAARFGGNRVAAWMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAI6</accession>
    <name>A0A6A6PAI6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Phosphomevalonate kinase</fullName>
            <ecNumber evidence="3 15">2.7.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_369064</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP</text>
            <dbReference type="Rhea" id="RHEA:16341"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:16342"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 15">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.2" evidence="3 15"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAI6"/>
    <dbReference type="OrthoDB" id="10262935at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004631">
        <property type="term" value="F:phosphomevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016005">
        <property type="entry name" value="Erg8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035102">
        <property type="entry name" value="Phosphomevalonate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31814">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31814:SF2">
        <property type="entry name" value="PHOSPHOMEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017288">
        <property type="entry name" value="PMK_GHMP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="12" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="16">
        <location>
            <begin position="172"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR017288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2460960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="486" mass="51900" checksum="F7E4A9B8AEB1F68C" modified="2020-06-17" version="1">MGSHSAAQAGETAVSAPGKVLLAGGYLVLDRDYTGLVFGLDARIHVVVQPVKTIEGVALREITVKSPQFTDATWEYGYSLSELGGGIKVTQLRASASLALQRNIFIETTLSYVLTYISTISRSAIPASSITILADNDYYSHPSSTITHDQRQAAPTPRSRFHTFHVPVHEAHKTGLGSSAALVTALTAALLAHYLPPRRFRLADQDPASSRRRLHNLAQAAHCAAQGKVGSGFDVAAAVYGSCLYRRFSAGLLAGLPEPGAQGFARRLAALVDEEEEEEEPRGGGDGVAWDGVVERDRVRIPRGVRLVMADVDCGSQTPGMVKKVLGWREGNAAEARRLWGLLQARNEALAEELVRLAAEDAGGAGAYDGLRRIIAGVRELIREMSAKTGVPIEPKSQTALLDACAAVPGVIDGLVPGAGGYDAIALLVEDREEVLEGLREFLKGWEGGASEEEGGKIGKVSMLGVREDMEGVRAEDPAEYKEWLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAS5</accession>
    <name>A0A6A6PAS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_376819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAS5"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000026">
        <property type="entry name" value="TBC (Tre-2/Bub2/Cdc16) domain family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="662"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="942" mass="102198" checksum="36CFDABC9B22A3D7" modified="2020-06-17" version="1">MATASGDTSRPHASSRTSSRKSSSSQSKPARRESSIAATDKSLTSFPSFSPPSDSDLLSALSRVRSEPSPTVASPADHLFPHAADSPTTATNTKSHRDSSAAASTNVLLDSLTEPAEPSPGARPLFNDTHTGQRSTVAALAASDDAQIELLLHQHEGGPVALVRQLTEDLARRDADMTEMTRKHEKRERALRRMLREHGASSADIDRTLYDLEFPPSSGSSVKEGRHNGFQEGRDERRPGSPDSSGHESDGSVQPRLGQAIRDAIPKKPHRLWQIARGRSISLGSDAKVVAKGTPLQASPKKEIPKKENESKKGKQEDREDAKTTKSVNSAVSAVPKRIMTPRPEGSVEMDSIIPDDNLPPALAPRKWNGDRERPIDQFGFLFDRARQERIAKVVKELQHDNIAEALNKPFSEVASTTSKRHSTGSILSKTSKGDSPSDSESHSLSRTNSLTSMEMPKDWHEYLRRAVAPSELLSATPTPAIGEAVSNHQPSTPTIAPTPTQIPARSALAEPSPTHEISNLAEISPPAFIAPRPAAANDSRTSSPRPLLLDQVALIKEIELRDRLDKERQQNWNAFLRANAEANRRAAVAAAKEVSISRSSTPVGGVSASNRPHSLLATEVSIAAAAVPPDDSNMLGVSEWWHQGTAGNDKRRAFAKLVHAGIPVALRPRIWTECSKAYALREPGEFARLLTAPRPNEAAGATAAAAAEHLRDIETDARRTLKNNIFFLHGPGQQMLTDVLVAYARRNPSLGYCQGLNVIAGNLLLVLPTAEDAFWVFCAMVERLLPSSYWDASLSGCVADTAVLARCARDLLPELHAHLYDALDVRLETLTVKWLLTAFAACLGGEALFRVWDILLCQREPAVFLVCVAIALLELNKDRLMACATLGEVAATLEGQLTNHATSIDGLIYAGYQLRKRIDRETVMALRSEVLGEEVARDMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB00</accession>
    <name>A0A6A6PB00_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_140068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB00"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16261" checksum="70A6A81E9CFCA093" modified="2020-06-17" version="1">MARALADCVPNSDPPPSSSPLHCFDKLAISGPDDPVLCDPYSPRRRALQKWLPPSQLALAGGEANSAVQGTTGPRSTRINWGSRSTFHRSGVHPTLCLLSIAGEPRGAISSPTWLAYCCRSCAALAFQLVPLPFVFCGVPYPFLLFFRTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM7</accession>
    <name>A0A6A6PBM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative lipoate-protein ligase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_278086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LplA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM7"/>
    <dbReference type="OrthoDB" id="201621at2759"/>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017118">
        <property type="term" value="F:lipoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16443">
        <property type="entry name" value="LplA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="LIPOATE-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561:SF3">
        <property type="entry name" value="LIPOYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="6">
        <location>
            <begin position="63"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="388" mass="43401" checksum="72E0705C8C1CC444" modified="2020-06-17" version="1">MSPSRGPLRLFRATLKYSQLQNCRLFCSLAENVTGSRIQSYTSRSSDPYLNLSIEHYLLQKSPPDSAILFLYTNRPCIVIGRNQNPWVEVNLGLLDAATGTRDTATDSTKPPALGSVDLVRRRSGGGTVFHDRGNVNWTVISPRDGFTRDKHAEMVVRALRGLGIDRARVNERHDIVLDQGQRSRKAGLSDDEHTTPYMANGSAAPQPLKVSGSAYKLTRTRALHHATCLLQSPNLNLIPDYLHSPAKPYIEARGVASVSSPVGNIGIEITPFERAVFEEFVALYDKEQSQKDMEEVGVDSLEISDIRKGYDELKTLDWMYAQTPQFTISKEFGNDVFSMTVRHGSVLESTHLSIEMPKLHEIKDWRRYASTDIGNWLNNILLIPSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC90</accession>
    <name>A0A6A6PC90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_412854</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC90"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="408" mass="46898" checksum="71D2C37A9165A0F0" modified="2020-06-17" version="1">MFPCPSSARTLFSTARSLYTAPKSLPLDVLIEEELIPGYDPKRFYHPNPGEILDGDLSRKQRLDGGTTSTVSHDGATARHELDISDHVDRAKSDESRYRYVRTVEDSCEISGPNRSHLCLVLEPMREPIWLLRRRLGSDKVTRDFLPFFKLYIIVLLDGLDYLYTKCSIIHTDLKLDNILVTFGDKSVIDEFVQGQTQEPMPRKVLDDWTVYLSYNDFGHLRLVRDTPALMKICPKIIDFDLAQRGDGQGLLIHPIQVDHCRAPEVWDLLAGEELFQKFNSKDGTYSARHHLAEIIALLGPVPPGLMKRERNMRHWQWALDAVNAKGKLCNNGADFYGGPFFDDNGHFVGNDFVPSDRHLKDIVPEYIIDEEAEIFLSFMRRMLYWLPEERATAEELQNHPWLDLARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC99</accession>
    <name>A0A6A6PC99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_278885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC99"/>
    <dbReference type="OrthoDB" id="2382881at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="34"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="143"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="355" mass="39756" checksum="7F0DFC7CDF35EE44" modified="2020-06-17" version="1">MPEPRDESKPLPPPSKKLPASDVLLKTEQAKRWMKRYRTEVAASSSSLLSTFVAYPLDSVKTRMQAYKFASFADCVQITYKTEGFKGFWRGVWSPLASITLVRTASFSIYQKAKYTYDDWIHRATGHSPLVIANTRDALPNLFTVGCFGAAGATSGALITAIACPFELTKLSAQISVLMAKRNPNSGSDEVIRQSYQEKGTFRTAQNIVKHRGFMGLYSGFHFHLLRDTFGTAIYFMTYESSKQLLANARGNSPTSPFAVVIAGGLCGIVSWAAIYPIDSAKSIYQRNCLTSHRDRTHTPKIQFFNPRMYRGLGVSMSRSCVINAIFFSAFEIMKKWVNRLEVDEELLRANRPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCH7</accession>
    <name>A0A6A6PCH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome oxidase complex assembly protein 1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCH7"/>
    <dbReference type="OrthoDB" id="2100652at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042432">
        <property type="entry name" value="Coa1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28523">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28523:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22817" checksum="D1E6534024C965A0" modified="2020-06-17" version="1">MRPQPFFPRPLGRATAKPRRPTQAPRARGRGLVAPPRPGSQPWQNLMMSRRSDRELPPAKGPNPWLRSLPVFLPVAGAALLALLNYQRQSSSVVGSSLYALRTHPRAREALGDNVYFAHKWPWIWGELNQLHGRIDISFKVKGTRGSGYMRFRAVRKHRMGFFETQEWSLTMDDGTVLQLLTDEAGASPLPQRGDQEGFAGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCS8</accession>
    <name>A0A6A6PCS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_92711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCS8"/>
    <dbReference type="OrthoDB" id="1930760at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887:SF41">
        <property type="entry name" value="THIOREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="22"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="294" mass="31822" checksum="26D3D014636F902A" modified="2020-06-17" version="1">MSAPLVNNSGTDAGPPRMTFHIDITFDFPCPWCYIGHRRLSRAIDLYRKVYPGGRNDVFQFHWHPFYLSGTASLCETASDSATISLGSANCTSSACAPSSSVSATEVLSTRFADQPERAAAVVDRLHQVGRSEGILFDFSPGTGMKIPRAGTRDVHRLVRLVDRKYGDVAAQALVEQLYHGIYEEGVDVGEKEELVRLAAGVKEASCGSDKVLSIDEGTIRAWMESDEGCEEIDKEAERARAGEGVTGVPTFVVSGSKASREALEGAHDVGDWLEVLTKIKQANEEHSGAKISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCS9</accession>
    <name>A0A6A6PCS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_368782</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCS9"/>
    <dbReference type="OrthoDB" id="1507364at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000069">
        <property type="entry name" value="ER associated DnaJ chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015399">
        <property type="entry name" value="DUF1977_DnaJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09320">
        <property type="entry name" value="DUF1977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="434" mass="48468" checksum="03613A08E8262B3A" modified="2020-06-17" version="1">MSASASGADTNGSASARHRAHHDGREGRAYTAEQKSAVIRVRRCSPTAFYDILGLEEVRTTVTDTEIKKAYRKLSLLTHPDKNGYDGADEAFKMVSRAFQILSDPDKKAKFDRFGGDPDNRFSSASAGAGASPFSGFARSPGGPSARAGGPGATFFEEEISPEEMFRQFFGGGMGGFGGPFGEQFLRSHQHQYQHRYRYQQQSQQHQYQRRYHYQQQSMQHQYHQQPQIQDLYFKFFPPLMKTEGGGMFDTGPGFVFNIGGGPGIRVHQFGGMNPRRRPHPHAQAAAGQAAADSGLSSFISLLPLLLLFIIPILSSIFSGGSSTGLSGGPSYRFDSAVPPHTMQRMTPRLKIPYWVDPAETEDLSPRRWREVDKQAEVKYMGQLNVECGLETRRQEQLVSEAQGWFFQDQDKMRAARSMEKKSCKRRDDLLGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCU6</accession>
    <name>A0A6A6PCU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_1332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCU6"/>
    <dbReference type="OrthoDB" id="5422351at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625:SF1">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE GLYCOGEN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="684" mass="73864" checksum="79BBF0505C3E8270" modified="2020-06-17" version="1">MDSTALVAFIFEAPFHAQTVELLGSWDNFATPYRMQMDTRKGALHWTGCFSFNDIVFDGDLYKLSSKRNGGLRMGGTYWYYYRIDGDVEYHDPRKPATTSCPLLPGQSVNLLEIPFDSTFANVKPGAPINKISYHSAFTLDPNAKFLLPKPVPETPRSLSPSPARRQAKSARLAVSAEDLRAQTRVHLPPSPVSPPDSSGFLRSAPAGKAIASRPSTSRGADARKTKSASGSPSLSFKSAFALFKGERPSNGDLKSSGSSERGRSRRRRLSRRHSAKELEIGRPVLISRTDEGRYCIPLSSPEQHDQNDVPQFEPQQPAPGLSSNVAFGMSPLKSNPVDADKDILETLGQQHCWGDECISPCTSNAPQRSSDDMTRYPYLSDPMSTSSRAPSPFRNPFASVWEEEEDFGLDIREIEPSPPLRSRFSAWTIDSEDLEDDGPEPGPQGRDGKATAEAGADAEDDEISSPTFSGFTESTASWARTPCHEDADRDVFEYPFDQVSDVVEWYGADGADGEEDQRRHEDSMSMLPAHATATTTAAITSISAASTTTLTATTTTTGSANTAAPSTTRAPPPKPLQLDLQPPPHPYHFAHLDLRSPPSGGAGPDVRRKTACFGISPASSPAATQEEFPAEVSGRRGQGSGVGSVGGVEMGLAKGMGIEVDVRQPPAVEMLVSEFGYLGEAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEA7</accession>
    <name>A0A6A6PEA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7770 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEA7"/>
    <dbReference type="OrthoDB" id="3527137at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056672">
        <property type="entry name" value="DUF7770"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24968">
        <property type="entry name" value="DUF7770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7770" evidence="1">
        <location>
            <begin position="25"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="19513" checksum="82EAF164F2BF10E3" modified="2020-06-17" version="1">MSFQTAQYIPSSRRDAIRALPVDYVHAVGHSRKPWGNRFTNHWCLYLQTGENSSVRIDMVPSYYVASTVIQGGSKGNLIISKLEYEYSSNATKVVTIQPPQGLCVSDVIDTLLAAGRDKYEFNGEGVGCRMWTADALNLLEKKGWGSSTNYEAAKQAIAKLWPDGTDLPLDHGAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEB6</accession>
    <name>A0A6A6PEB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_93972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEB6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="21264" checksum="3A43E57C2F528424" modified="2020-06-17" version="1">MARLSRQNETWLHDAVVGRLTARLKRYSTPGEEGHRTPQGGLRVTPRMRTTVYATHKAEAAVVTKSVARKFCWHVLRTIYLGRTKRKRRSAQIESHAQQSKSLTYSVEQQESRGTNPQLRWCHGAIGRSAAAFPCFETRRGRRRGSGGATKCSTSTSSGFHRNRIIALALAGAWGGSGGDVSRRLRLFVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PER3</accession>
    <name>A0A6A6PER3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_3102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PER3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="20175" checksum="69FABA1DCFE12953" modified="2020-06-17" version="1">MLFSTFESGEYACCKCRMIGGIRRTAVGKRVSSLVPASAPFRRRRSPARREGMSPADRRGSKQPELEVRRSGTPDTPGAPWSNAVFRLSVWDSSSSQDPLGGSDETGEVKLARGRKPLIWAPVALKQHTVNASRPGRTVLSTCQGGCGRRGGPRDKAVSETIPCREEYASPCVRPSEPGSAWCGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PET0</accession>
    <name>A0A6A6PET0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_331113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PET0"/>
    <dbReference type="OrthoDB" id="3777207at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="445"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="871" mass="94225" checksum="39AA51E941451711" modified="2020-06-17" version="1">MMLNDQAFDAFVYQSAPTSVTMHREPLGYLKPLVEEIGQHVDDFLAVGTHFLRHFSVEILTIRLETDRSIISHLLGAAQLWKSFLDLLTCQSASVKSLLEDESIELWTEGASDPTDLKGQVENAVASLDEYADKITHELIHETDALIQKITNLIAIDEAYRSRDNNASIRRLSWITFIFLPLVFASGVFGMNIDLLSNDPPWVYYLYFIIPLCFLVAICYLLLRYRRAIWTWVIKTRQNPREDDIELQALLMNTATSGIPQLVSNANATTGAARSAGEDLSLLKALSTGAVDAALELLGQGRVDVNDRDAGGATALHHAAGKGLVEVTRRLLLKGSSVEQKDRGGRTPIDWAIASGSDACLALVLFHKIHPLALNENRQPMKSAMHYAAVTAEVLLLDAVVEAGFSREDRDEGGRTPLFAALETMDAGFFNHCIGVFDSNAIDHDGMGIIHYAVALDFPGAVSSLLAHGANVNARDSWQQTPIMCFNATKYKSSIDILELLVEHGADLNAQDMDGNTLCHHVALGSDRGDIVQFIISNGGIISIQNRAGSTPHHLAAGAGNAAVLKLLVDEDPFVLGWTNNESLTPIELAARNGHIELVYGVLRPAVPHDGIWADRLAHVEETLVALAIDADDVARLQLLHAVGVDLTAAAPPPVSPATPNIAEDPRQQRQAVDLDNDVDAVLATPFGRAVVGNREAATAYLLGLGCSASLGAAVHDGSRRSLLQVALDAGAAATTRLLLDAGAPVEGVDSWGSTVLHAAAQAGDVECARRIVSRMEAEGKMELVSSRDSYGWTPLDLAAFYRHPDVEELLHPGGEVTFAWERRPPQGLSAETQRLVEMRARVEPEEGIGEDAAISELPIIQFPATSTRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKX6</accession>
    <name>A0A6A6NKX6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_407070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKX6"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="37300" checksum="FCD5E47EFA6F5DC2" modified="2020-06-17" version="1">MSHRRSVSWADRTHDEFLNQPSPYYDKASEEPFTFPAQSTESIWSQFVAKIWSLFKPKQRYVNFAPLPIRQDAHASEVYEKPVAALSEDGTPRTWLLTTRWTFALFAVLIVSLSFNLAFWLKSVSDPWSVQTHVEVLTSNASYTNTYHEYDLLWTEVLGGSLGEVYTSEGRDDGLTRKAGISMFHQLHCLAGIRSAIQQLQEGKEIGFSEETDTSEHRGHWPHCFDYLRQVLLCHADDSVELSQLESGQWRISGYRNKRICRDHKKLYEETKCGPQGCPGGKYFVPGEDFSKIKVAEESDRRGYVDEREHVGRGEYSVEPDKDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLP5</accession>
    <name>A0A6A6NLP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLP5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025489765" evidence="1">
        <location>
            <begin position="21"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="147" mass="17703" checksum="8679BAF18D672662" modified="2020-06-17" version="1">MKFFKAFFVFTVAFSVAAFATQFLLVDETEYATVDETNALDLPHRPKPNTKIKNPVHRWQGFAERLNERHTNLTKYNPDKYYTELQMCMSRRPWSDNVHKSKKCCKKLWKHYYKELKAYYKEELFYLNKGIDAAFGSKWGRKPQRWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLP6</accession>
    <name>A0A6A6NLP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sec63 Brl domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_417588</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000393">
        <property type="term" value="P:spliceosomal conformational changes to generate catalytic conformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18019">
        <property type="entry name" value="DEXHc_Brr2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000005">
        <property type="entry name" value="Pre-mRNA splicing helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000133">
        <property type="entry name" value="Pre-mRNA splicing helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000368">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000254">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048863">
        <property type="entry name" value="BRR2_plug"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21188">
        <property type="entry name" value="BRR2_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="1502"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="1725"/>
            <end position="1933"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="2355"/>
            <end position="2534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="979"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1185"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="996"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1026"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1204"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1452"/>
            <end position="1470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="3173" mass="358142" checksum="5820B4AD62C76ACA" modified="2020-06-17" version="1">MDRANILPLTGLLVGTCYLSTSYQQSYAFDRPAHSATVVLALCGAAVLALERLLPTHRNATEKLRYEAIPLDDIDGDERPARRDRSPSLPIDVHERGARKNPRALRWMFGFLVVAVCARMEIMRRVIKDVECANRMSYEPLIPFVLAVADFWSSRKGRVRVTEDDPDDTIYDDMFRSVAQSSLRYVVTTLVMAVCGMTILLRDALPGSSYICPASLPIFSIVPVLQFFGFVLDALLVLILWRLLDRGVAGRAPLGLSGPRLVGLASLFSAAFWVAVGVVVYFAKAEYRDWMLAVSPFYVRSLAKAALFITLTVVGGLRCVHYYGAMKTAMIATFASIAYTDFVAAWEHRIPFPPRPSVGVVFVLLAFYVVFVSFLFIEASREIRFRGRAHVFSFKIPAWSVPFLILLFIGRTILWSSRPTHQKYHPVDVLIHTARVAYEDWEKQAASSNSIGQATEEYRQRYRRNPPPNFDKWYEYAITRESPVIDDFDNIYDDLLPFWAVSPEDIRQRTWEAIANQNNDAGGIQIRNGKASISNNVVPTHKWMLEGIIDIIAKFAEFLPDMDLAFNLNDESRVTVPYEEIERMKATAKRSVAPDRDKVMLEFSENRKSQWKDVPKERITKTDFVELSLRRTFEDFGSVGCPPDSPARTQRLWNVQDLCTSCTAPHSLGQFLQNWTVAADVCHQPDLADLHGLYLSPAAFKASRKLYPIFSQSKPGGFNDIRYPSAWNYEDKVAYEPSDEFPDGPFRDKTNALFWRGVTSEGVSGGSDAWRGMTRQRMVHLATNVSTPQMVLLPRSSPREDSEESKPTYFSYANVEPSVLQSAVSASVRFVSPIARCGGGDCADQAAEFGFAPRTLSFQSHWEYRFLLDADGAGFSGRFLPFLQSRSLPFKAALFREWWEGRVMAWKHFVPLDMRGQGLWSTLAYFAGFEGEAEFRGGGKGRSGTRNVAWPARENVLGQYKYAAMSNLVLQADRRFVSRRTDENTGDPESLAGRINIRDMGSRVTREDAPQQPSRKPKGPSGIDRGAIREGEDVLEREQKKRKLGGRDPASAGQLQGTGILSQDLVVEDLRYKPRTPATRDTYQLITTIVGRNLGDVPSHVTRSAADAILEYLKDEEMKDYDRKKEIDEILGNSMSPKEFNELVNLGKKITDYDAQDEDEEMAEAGEGGEEANLDERQGVAVVFDDSEEEEGGGQTFEVRDGADTSDEEEEDEGKDEDEQNGAAGGNVEVLGSDEEEEVVIGSRAKDAAAKTEDSKVVLAFDIDAYWLQRQIGYIYEDAHTQQEKTQEALQILAGVTEDGEEQSLRDIENDLMELFEYEHHELVEKLVLNRDKVVWVTRWRRAAEDSNARVAVEREMIAEGHRRILDELRTREKPDEAPDATIAKKMKLDLMDVDVPSRDVEMKDAKEAGLVGGLQPKKLINLENLVFDQGNHLMTNPNVKLPQGSTKRPGKGYEEIHVPPPKAKRDPSEPKNMPTSALPDWARRGFGSSKELNRIQTRCFPTAFNDDGNMLICAPTGSGKTNVAMLAMLREIGKHRNPETGEISLDDFKIIYIAPLKALVQEQVGNFGKRLEPYGIRVAELTGDRQLTKQQIAEAQIIVTTPEKWDVITRKATESSYTNLVRLICIDEIHLLHDDRGPVLESIVARTIRRTEQTGDPVRIVGLSATLPNYRDVASFLRVDPSKGLFHFDGSFRPCPLRQEFIGVTDRKPIKQLKTMNDVCYNKVLEQVGQNRNQMLIFVHSRKETAKTAKHIRDKALEMDTIGQILRVDAASREILKEEGEGVSNADLKDLMPYGFGIHHAGMSRADRNSVEELFSEGHLQVLVCTATLAWGVNLPAHTVIIKGTQVYSPEKGSWVELSPQDVLQMLGRAGRPQYDTFGEGIIITTQTELQYYLSLMNQQLPIESQFMSKLADNLNAEIVLGNVRSRDEGVEWLGYTYLFVRMLRSPGLYSVGADYEHDNLLEQKRVDLIHSAATILERTNLIKYEKRTGRLQSTELGRVASHYYISHASMLTYNMHIQPSVSTIELFRIFALSEEFKYIPVRQEEKLEISKLVQSVPIPVKEGIDEPHAKINVLLQAYISRLKLEGLALMADMVYVTQSAGRILRAIFDIALKKGWASVAKTALDLCKMAEKRMWPIMTPLRQFPNCSRDIIQKAERIDVPWSSYFDLDPPRMGELLGMPKAGKTVCSLVSKFPRLEIQAQVQPMTRSLLRVELSITPSFEWDNELHGAAEGFWILAEDCDGEEILFHDQFLLRREYAMSEMNEHLVEFTVPITDPMPPNYFITVVSDRWMHSETKIAVSFQKLILPEKFPPHTPLLDLQPLPVSALKLPEYQELYHNQNWDRFNKVQTQVFNSLFSSDDNVFVGASAGMGKTVCAEFALLRHWAKPEAAGKRRAVYIAPFQELVDTRLKDWQGRLSGLRGGKQIVKLTGETTADLRLLDKGDVILATPSQWDVMSRQWQRRKNVQSVGLFIADELHMIGGQGGYTYETIVSRMQAMTLQLESELRIVGLSVSLSNARDIGEWIGASKHTIFNFSPHVRSVPLELHVQSFSIPHFPSLMLAMAKPAYQAVLQLAPDKPAIIFVPSRKQVRATALDILANCVADDDEDRFLHASVEDLAPVLERVDERALADSLSHGIAYYHEALTPFDKRAVEHFFKVGAVQLMLVSRDCCWEINCNANFVIVMGTQFFEGREHRYLDYPISEVLQMFGKAGRTGEDKTAKGMLMVPAVKRDYYKKFLNEALPIESHLQHYLPDAFVAEVSTKVIGSTQDAVDWMTYTYFYRRLLANPSYYGLTDTTHDGLSAFLSELVENTLKELIDAKIIELDEEDDTVTPLNPAMIAAYYNISFVTMQTLLLSLNSRTKRKGILEIITSATEFEGIQIRRHEDHILRRIYDRVPIKMVQESYESPHFKAFILLQAYFSRMQLPVDLGKDQDMILSRVLPLLQATVDVLSSDGHLNAIAAMEMSQMVVQAMWDRDSPLKQIPHFDNGVVKAASEFGISDISEFLDKMDPDSNPDYDKLVKRLGLSQKQLADAAAFTNESYPNLDLEFEVEDADEVAAGSPALLNVNITRELDEDEEPRMVVHAPFFPGEKTENWWLVVGEESSKSLLAIKRITVGRQLKTKLEFVVPSPGRHKLMLYLMCDSYVGVDQALEFDVEAAEGMDEDESEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMD1</accession>
    <name>A0A6A6NMD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_173392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMD1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18236" checksum="87C95132385C24AD" modified="2020-06-17" version="1">MLHVCALVPQYGSGTRREAAALDPSPPMVLPRTGQRPRVDRRMPRSVCLWYESNFCRRTAWAAASCKTHVTISTCSHLGGLQRTVGRRVQETLFYRRHKCLADSTRGRDMSTKSKAGGVRKGSPGMGCHLQGPRPVDVGALRLEFARSAICLQLVTPKLHIPSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMK3</accession>
    <name>A0A6A6NMK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMK3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="481" mass="51867" checksum="370E572C7860B123" modified="2020-06-17" version="1">MSQPPPANGAPQDPVTDLATDDNLIRSTGETVHRLIQLISRNSVSGAFVGLQDSLDVMSVTHETDMNEIMGYLKRIEGALENSTTQHTEDNARILERFCRLESVQHDLNVAKKDISDLIVGINSLEQEVGATKNVVTAFTRELAKFNDVPSIVEASEDDIISLRHKVERLGGLPDTMSTIHNSVQTIRNTVSEALSRLNNPPADDFALRQEINTIKDRMDIMRADVVSAVVAELDKRDDAAQKPQNEAGRSNVPERSNIRFYCSSSSSAPALAQAYEPCSPTHSPHHTFENVPETDVDVRTPEQLVGHKASPSPSESRFAPLYSPNFDAGSAYVPASSPSAISEEEAIRGSNRAHGTIAVSAKAPQDFPRPPHETRLTSMIHNKEATITSLKRSLDVTRSSSSSSPEPASAPAPKRNSVVVATAVADAESAPPPPGPPPRKRSLLPGAADRRSAAASASRMRSRRKAPAGGRNGRAGRDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN46</accession>
    <name>A0A6A6NN46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN46"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="23701" checksum="C7D9D6FFF63F9FE7" modified="2020-06-17" version="1">MVAFDASTGTPSDRSSNSHASASAASSSRPISSDNPTPHSFRTTTVHTATATAADIHHFIICLAANTIENHSSELRIINQAVSSLRHPFPPTASFAFLSLHKEQRAAADRLKAYGAVASMVKTWSSEAESNVGVVMVGVGGLPRQRGRERQLTKGMIAIAAGTAKVAGRLRRDFCPQQHDGQKLDHLLEAATRFRYAWENGRTVIVPRYEGWRYEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNP5</accession>
    <name>A0A6A6NNP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_355743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNP5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="76" mass="8609" checksum="A623AA27360408D8" modified="2020-06-17" version="1">MHINKNKPCPTPPIRLSVPVSRSRGKNAQQRRKVSPPTHFPKRPKNGSPLERNAIPCTQPSPFQRLPKPAPTQRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNQ4</accession>
    <name>A0A6A6NNQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_143913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNQ4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="227" mass="24431" checksum="96DC3BDFED0FBEAC" modified="2020-06-17" version="1">MLAILISIGRTGRRRSGAPNVAAARCRGNSAALQLSWPIAEEMAAGLLAPLRSHLRREQWGRVEGDRRGESARGNGDQRRPSDIPAGSGPWERVAGGASPSSAFYSSDSHWRRLQGRRRWGQGQRDGGGKTDSVQKRTARRNGQQREDGRGGKAAAVQLEGAPDPAARLLRGRLPSGRFGRGRPVTSRLFSCPFCLKRSARLCGGADGWWTAGNRAYIACSCSIGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPH2</accession>
    <name>A0A6A6NPH2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_128416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPH2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="29239" checksum="56747C7A49E0BA9A" modified="2020-06-17" version="1">MVDVQADQITVTRPFKRNLLRSGPFAETFYQSDDTLTSSIQLHPCFVDKCGKGLQSGIVAHYCHSSCYESVGARDATKDIISAALYDFSPSSQWQRERESFWVDKMASWFYDLVTPHLPLEMWRMIASDVAPDPISLGPFIVRRWSALSHPEHRPDAIEVPILVRFGSRSLENKRYVSHVVRNSKKESSPIARGYLWVGSDCRGIVAVHFERPEVEQDIWWQRIRLEQSKKLRLAWDVSSFPSFNSLLLIIGLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPX6</accession>
    <name>A0A6A6NPX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_356485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPX6"/>
    <dbReference type="OrthoDB" id="4215304at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000008">
        <property type="entry name" value="Beta-N-acetylglucosaminidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000013">
        <property type="entry name" value="Glycoside hydrolase family 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050226">
        <property type="entry name" value="NagZ_Beta-hexosaminidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480">
        <property type="entry name" value="BETA-HEXOSAMINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="6">
        <location>
            <begin position="16"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="644"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="934" mass="100902" checksum="0BEF1662F64754FA" modified="2020-06-17" version="1">MAAGKVDHLDPVWDDLDKTLGQLFMMGFDGTTVTPQIRTLIEKHHIGSILLTAKNLKSAEDTTKLVYELQKCAHDAGHPVPLCIGVDQENGGVNSLFDEIYIRQFPSAMGLAATGSTELTYEVAKATAQEIAACGINWIFGPCLDVLTNARNQPLGVRTTGDDPQEVSNYGIAFMKGYKEAGLATLGKHFPSYGNLEFLGSALDVPIITESLEQLSLSALVPFRNAIQQGIDSMMVGGCAMSSAGLNVMHACLSDQVVEGLLRTDLKFDGVVVSECLEMEALSHNIGVGGGTVMAVGAGCDVVLLCRSFSVQQDAIAGLKLGIENSMVTKSRIKESLRRVLTLKAKCTDWASALNPPGIKLLSTMQPSHTQLSTRAYNSSISVVRDKNHLIPLSNLIDPEEELLLLTPLVKPLAASAASRAVSETISAGSPEPAVWERSASVMSGERIFRELGRSLARHRNGRVLHTSYTANGVRPVHENLINRASAIIVLTADANRNLYQQGFTKHVSMICNMQYSTGGEKREKPLIVVAVSSPYDFALDSTIGTYICTYDFTETSLNSLAKVLYGEIVPTGSVPGTISHSQKLHQSRQHWLVEMFNEERDANALDSLINAVTEGTPPNQRSELSGSTSNTFLLHNPDVIEAHFVVRNSSTQQLYGFCSTYFFKATGTGAIGALFVDPARRKLSIGHSLHNRAIRTLLQRDGVKRFQLGSRLPSVFLGIPTGHSSERKRLRSWFANMGWNTALSRPVCSMVARNLGAWAPPDGMAKSLQGAGAEFDLVFGWEYAAQILDHIKTSNRQGLAEVYKLALADSAYCGVIRAKRADDPGTIVGSVVLYNVNSHLAEFVPVIKDMSDACGGISSPVISPAVGEYSTLLQGLILLGMRQLKAQNCSACVLDYMDGDGNIDALSAMGFEVLHNFEEVSCDAATWTMVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPX8</accession>
    <name>A0A6A6NPX8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_355877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPX8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="210" mass="22532" checksum="3ADF3F0B77D41A89" modified="2020-06-17" version="1">MPCHANPEARARAQRPLGGLACCRWLPLQRVYSDGRAVGDMGGGGGVGARVPCMEACLLRGRGAFVGCCACVRACMRACMGVWSVGWWGEKSGFGGAVVEEGVAVKGVWRMVSGLDGRQVWLRLACLLLLAVEEVGSSGETSGWVAGCAGWRPSSWLVLSVRLHMYIETVALSETMFLIGDRILNARTLVTELEIHDLLTHSLKLCLSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ44</accession>
    <name>A0A6A6NQ44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_127586</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
            <location evidence="1 11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dynein light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ44"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043935">
        <property type="term" value="P:sexual sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 11" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="10889" checksum="70D3031BEA6B6DF0" modified="2020-06-17" version="1">MASEKSEKLEAQVKSTDMNDDMQQESIDVATEAMSKYNIEKDIAQYIKKEFDSRKGATWHCIVGRNFGSFVTHESKHFIYFYLGHCAILLFKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ76</accession>
    <name>A0A6A6NQ76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ76"/>
    <dbReference type="OrthoDB" id="16824at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8447" checksum="37D5092979527233" modified="2020-06-17" version="1">MVLGRIAHYAFDAVLISAFLAGVRRSTGLTPSVRAESVSDSPSVKKWVDNYLWVGETVMDQSVAFMGTSSYFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQS1</accession>
    <name>A0A6A6NQS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyl-CoA dehydrogenase/oxidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_354370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQS1"/>
    <dbReference type="OrthoDB" id="10016597at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6562" checksum="DD855DCFA3F84C02" modified="2020-06-17" version="1">MDVKMRMDASRLLTWKALHCLENGPGDLKARAELCYEAKIFCTESAVRSVVDAMKAVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR05</accession>
    <name>A0A6A6NR05_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR05"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="31715" checksum="683133F5549DD4A5" modified="2020-06-17" version="1">MGGGCYGARPHTGHHGAHPATTTATPPSKGKPFSAWRSRPSWKSRDTLDGPFSTPLATATALVTLLSPSRSHFTDRRTPRLSLSLLFGDLARDEEDEESAKAKRERQNRAQSGSPAPLHRPPRQNAAGSLPRLASAGSQAASAVLSPPTPSDHEPPELRPRRAHQAAEQRSSPHPDFSHRHPSPLLLPPASFPPSRLFTCLPHPLASPLCAPFGLPGTTSRPPPDHAPDTMDDAARIRAICLGGRSRRPLPPRPSRQRAGLRRAAVAEDVRQLHIRRAAEPEHALRPRLRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRW7</accession>
    <name>A0A6A6NRW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRW7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="18965" checksum="1FE7E534A18B14EA" modified="2020-06-17" version="1">MVQVEYSTETWLRPVQDLQSKLLSHNVEYERGETKRQIFGNVEREQFVLVFKVLKGEAKAYRPDDDGKGTMSNIQLCGSSEMRADVYADPLKQNPADYDAWYNEDGWTNHMRSWRQDPHPVGKTSFDYMYEVGSRAQWYEQTIVTYMRERKIESREMETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS25</accession>
    <name>A0A6A6NS25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FYVE zinc finger-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_308400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS25"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="145"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="490" mass="52452" checksum="401303E737E3731A" modified="2020-06-17" version="1" fragment="single">MQRQQQQQQRRQGPRAAPESQTSHLPGSSMAAPIDLSSPPPPWQGSSFPGDRESGGTARHGRGFGSFGGGQTRSGDNAGGDGDNHRRGASDYGPSSADASNTAGAGGAARARHRGDDGPRQSLRGQTQGGSRRESDIVLPKWQLDSDVTRCPVCHTQFTWYFRKHHCRKCGRVVCANCSPHRITIPRQFIVHPPTPANIIDLTDDDGFFGGQFSNPALGGGEEVRVCNPCVPDPNFSPPPQQFAGMDPNHRQQGQGYWPFPEFNNNHNNDQANPNNNNDNNGLPFLPPHPGRPHNVSFNNARAFQLPPRSPGVVPHHRSTLSEAALNNYAGHSAGSPAAFEPPPDLRRNIDPSHGSFPSEQQQTGSSFPLLGRLLYGSGSNTAGDSAAAHQFPGFGPPPVPGSGNQGNAAASSSNTPTPPPPPGVPNYHDMFQPQFGPTPGPQRRPGLLPQAPSPRQHQPHAPAAAPPQFPQHHHRPHAASLSHQQHQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSH5</accession>
    <name>A0A6A6NSH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LYR motif-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_110224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSH5"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd20262">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045293">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF0">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="7">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="95" mass="11249" checksum="3CAAD270CA494213" modified="2020-06-17" version="1">MRWLSRSYATACGGRRPRSKRPALGLEHFLQRQRVLALWRDIVRSINKIPASSTRREMRDFARSEFEWNRHVTDITHIRYLVSVSWELSRPSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSR5</accession>
    <name>A0A6A6NSR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_94606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSR5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="19066" checksum="AF0CB36CAED33286" modified="2020-06-17" version="1">MVVVLRRFVACFFMLLLFFFLTGTDCFAGHGQLLIHSGFDSAILPLASLIALAFSPLLSGSSRETQLLPSDTNVFEFYIAFRLALASPFATIRAFSPLRVYCCWGSKFSNGNEVKAIGHWKSRDSSTENFLLLLRNGIFFFFGKEGFFSVVFDIEGNAKTAPRLCVCTWPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSS7</accession>
    <name>A0A6A6NSS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_109363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSS7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="240" mass="25259" checksum="71F201FAB9BD579F" modified="2020-06-17" version="1">MLAAAVSDSRSIHPPAPRPPIGPAAPGCHVLSAVTRRLKEGQLLVEGGGLCVCAGARVADQPQGGQPPPSCSRPSFLPPPNRPASLGPAAVLGPSACPAPRPCHTRSSPTSQLPSGPQSLRRVGRRARHLASLDRRGAGDPCRPACSASTHPSPLFDLVIVEGFDPSLFLFPPPHSTSPVIVMPHHHPAALTLLAWLGPVARWPGAEDRAQCFCNCSFRPFPVACCRVRLGPHRHHPKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTS1</accession>
    <name>A0A6A6NTS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_290023</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTS1"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="305" mass="32628" checksum="53BEC7C3D2EFF185" modified="2020-06-17" version="1">MAWHDVDSWPTVLLGPTLTGILVTLLVAFLIPILLHQFLYRARTPKTLPTFLILGPSGSGKTSLFTQLERGTPSPTHISQVPATATATLPPSITTESNRYRSTEDPTLLAQRRITLIDTPGHGKLRHHALSRLSAPPASKTKSATVPSFPHALVFVVDAARLAPGSDSLAEAAAYLHDVLLALQRRHARARTSRGPGTVPVLVAANKMDLFTAAPAKVVARALEDEVGRVRESRAKGLLDSGGGGEGGRAEEDEDAGWLGEGGEGRFEFRQMEEVDVLVEVVGGNVLGGGGPDVQAWWEWIGRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTV2</accession>
    <name>A0A6A6NTV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTV2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="14390" checksum="A4ECE1938045231F" modified="2020-06-17" version="1">MGMGALYDGTAGTAWHGNGMEGKKGMGQGPAKRARINTPKHVFSILLSFSMYSPFPFLSLSLFLTPPFSKLEFSIHFQIFVSYFPLPIIYPYISPSGWARMRRSIVHRLGHFPVWFESSSHVARCTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTX4</accession>
    <name>A0A6A6NTX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_290686</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTX4"/>
    <dbReference type="OrthoDB" id="2382073at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="44"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="433" mass="47145" checksum="2DD822E58BD3A7B6" modified="2020-06-17" version="1">MHHGPGTPFPPACSPLERQLAQRLDRRRANSTLRSLTVAPPSSVDFSSNDFLSLAGSAELRAYFLCELAGDRSGCPPLLGSRGSRLLDGNSAYAEAVEREVAAFHGAAAGLLCNSGFDANAGLFACVPQAGDAILYDELIHASVHDGMKLSRASRRVAFEHNSADDLGRRIEELLAAKPSFADGHGNVFVAVEAIYSMDGDLAPLAQIVELVERLLPRANGHVVVDEAHATGVLGPQGRGLVCELGLEKRVFARLHTFGKSLACSGAIILSSPIVRHYLVNYARPMIYTTFMSFPSLAAIRASYRYLEDGKSEILSSQLQNLIAYLHERLYELLSSLEDSTGLISMPMTRPRSPIFSVLTTRPRELAKHCQESGFIVRAVVPPTVPAGKERIRVCLHAGNTKDEIDGFISRLQEWLESRLAECKPLMARQSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUL3</accession>
    <name>A0A6A6NUL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUL3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="114" mass="13158" checksum="67D1B60A7B4FFDD3" modified="2020-06-17" version="1">MKSRYTMRDSEHFIMPAPEDVRTLPCAYYYTSYIFSTNKPKKLSEGDCVDYKHKTENQTKPSAIYPVHAHDFSVYLFQRISSRTFRSWNSSSDTSSMVGVKCLPGLEVHSNPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV47</accession>
    <name>A0A6A6NV47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA ligase/cyclic nucleotide phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_396681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV47"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="35138" checksum="6E0100206C12DA29" modified="2020-06-17" version="1">MEPVPVHTSNTFEDFSGITSSSSDNPYDALIDASQNDPVQIQARYSTHRSMRNAQQKAKLLAPDFDGVQIDPVLLRLSDSSVEPGYADPRHCLVFWARPPQAVKNLIAQIQQKLLAAAPNLWLMPPDNLHMTTLEITHSQTASTIHSLVASMRAAIPSIVNYTQTHRARLVRPLLSFDAQALALSFVPAAGESLPPGQAPADDAYSYHHLRRDVFALSRAAGVAVESRYVVPSAHLTVGRFVAGRDFEGDDGRLDRGKVAELVEAIDSVNEWLVEEFWPKREGGIREGGEWIVGQEKGLNCRMGTLWYGGGEDVELGKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV72</accession>
    <name>A0A6A6NV72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_289243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV72"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="266" mass="28117" checksum="4129F5920D8BB889" modified="2020-06-17" version="1">MATPHQHGHGHGHGHKHEREHFDAEAADWDSKPGLKEASRDAMEAIMKYVPGMESEGKNKDVLEIGCGTGLLSYMLAPHVRTLLGLDTSAGMIAAFDAKRAAGTAAAPNVAALELELAAAADPALVAASRALLERAGAGADADAAAGTFDLVVSHLTMHHIPDMRALLALVHDGVLRPGGYVAVTDFEDTGPGAELFHPRDKRHLPERHGLVPGEMEALLREVGFDEVSVVRGAFEMVHEVEPEENGGKKTRGFPFVVCVGGKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVE0</accession>
    <name>A0A6A6NVE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_306310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVE0"/>
    <dbReference type="OrthoDB" id="5428863at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="14259" checksum="0EC4DF098129698A" modified="2020-06-17" version="1" fragment="single">MEKIYHHADFTIIASGSPNASYGLPGVRGTPRIPLSHAKFGGTTFAPFETLSSELSRSVWSTRGWTLQEDLLSRRRLVFGKSQVFFGCRRLTLSENTRDFLTIEEPGMKRRGPGYLNKLNNAISSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVH5</accession>
    <name>A0A6A6NVH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_66538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVH5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="87" mass="9698" checksum="E8F4EC165B796C8C" modified="2020-06-17" version="1">MRAVFMCFLVSRASPKLRVAVVDEGIITPSLSAKTLYIVVCRSRIESHFTSLSPENPYSSARTIPHIQWDQRVARCCAALAFVEELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVL0</accession>
    <name>A0A6A6NVL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_365355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVL0"/>
    <dbReference type="OrthoDB" id="3361892at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032931">
        <property type="term" value="F:histone H3K56 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016849">
        <property type="entry name" value="Rtt109"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF2">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE RTT109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51728">
        <property type="entry name" value="RTT109_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="389"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="633"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2455608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="697" mass="74180" checksum="5AAC46FA083D007C" modified="2020-06-17" version="1">MSASDGPGSCEKELRELLADALPAGLGLTFYHISTPPTRCAAIFAAPPGQKPQRTCCESHFLNVAIRSPENSSSNSSDSNDSGAGSGNNAATTIQKHQPSQIFVFAIEVFIYTTKTLTTLFVSKADSTGFLSLLSIPKTSGGSPVKAIASTFISFLVRHRQRPRTRLVVSLFARAQDQYIYPGSVDNGRKHVLDDRGLVRWWCRVLDPILREHPGALAEEPRAGKKAPEIEDQQQQQSAQDAGRRLAKENVATTGYLVVPGFDTRDTARFFPASVRADPPSAPARWRTAHPLRTIAPHASPAPPRCLVPRFPDDPKARFADELDEEIPALGAAGAGNGQLSESPRRGKGRWKSVTSLDGFWELMAFRQECSSGRLVGFVWVVFEPEGLRKGKGEKDKGVRKLDFGKNGADGVVLPPPGKEAEAGGKGGPDSTARRKASAEDMTSATPSPEASLTSSNTTQPTSPPTSEAGKDGPHRRHRRRPASRAAQLTGPIIPRLPRIKSAGSHGAATAPSNSTASSSLGIPERTPFYWWPAAPAGSRGAIVLPEPEYKRAHDLLLRLDFSGVHQARTSSRRKKRKSEDGDDAAMDAGGDGVNVLGAGLVRKKAKVGDGAPAASATAESCDNVLDVGLARKKRKSQDEDVVDSVAGGGTADAPGALEARSQKKRKSVDGDSSIVDGADVVNVLDAGLVRKKPKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVR6</accession>
    <name>A0A6A6NVR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_396188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVR6"/>
    <dbReference type="OrthoDB" id="66546at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22572">
        <property type="entry name" value="GCP5_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059169">
        <property type="entry name" value="GCP5_N_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032797">
        <property type="entry name" value="Mod21_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF33">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14609">
        <property type="entry name" value="GCP5-Mod21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-Tubulin ring complex non-core subunit mod21 N-terminal" evidence="8">
        <location>
            <begin position="69"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="238"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="552"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="855" mass="95488" checksum="83756E162F2500D0" modified="2020-06-17" version="1">MAHLAKITGLSEGLVASTTGLSSSNRPKEFKYHTDAAVRSLRSSATHHARTNQFDVQDHLGGLLEKFAIRNREDLADALDARLKEFAARSTALRWAPEILALFLELADRPLEKARVEDLEALAPPPLPKELTWADIIAEEPLDEEGIWDDVDYAEPSSDEDVPVKEKRRESESSEDEALEQEKDDREIAQSFVVIPDRTILDDVRKGQFWNQKAQTTHNTMMAENSVGTPSITELQAIREALFIIQGLSSSLFKWDASSDHISSKVEYALSHTGSSSFHALLESLARIASGLFRLRRWVSKAQSVPLLQSFQAAVQCRIRAFDKNITALQKRYLSTEGNPTVSLVEVRTVVEASSKPFLQLADLIERALSPQHPFQCLEILFEQTNIARMTGEADCFRFFGEIFFECLQIYLRPIRKWMEHGEVDRTDNLFFVGIADKSTDLASLWHDRYTLRRDATGAVHAPIFLHPAADRIFTTGKSAVFLKELGHYEKPSLIQEPPLSFEAVCDDPWLISPFTELFEVAFEEWVKSKYSLASFTLRERLYYEFGLGRAIDALEHIYLSKNGSLSLTFFEAIFDKVDRRLASWNDRFLLTELAQGIFGSVDCVDAERLIVRTTPQKQANKGSIKALSCIAIDYVLPWPLLNILHRTTLPTYQKLFTLLLQLTRTTTLLAADPSLKFDQHVPSGRDNPTRARTLRLRHRLLVFATALCAHVCAALAGSAAELRAALTRAADVDALTRAHDAFVARVAERCLVSRRLAPILEAVLGVLEVGCGFGEARRRWDAGGNRLRKMQEQFDRLSGFVVSGLRGIGRAAATSGAGEKGLEAGAGTGLGAGEFGWDMLVERLEGWGEDGKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVU8</accession>
    <name>A0A6A6NVU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVU8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025410845" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20686" checksum="8686C1D34A29E90E" modified="2020-06-17" version="1">MPKLALAVLLMLEYHCSSGQCGDAARQNRTTSSSASRSIARMPYNVSSVWLLEGLRSVMGRLCLRTTQADLQGCILLDERRQSIPMNSDDPAVLDLSEYANASQATPSTRHCVDFRAPISPQVVARVEHPDPSRGVKKGRRWQWNNGVAASVLFRVAFVRDNECRAVEGQNKGDSEMSNRCLGRMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWD4</accession>
    <name>A0A6A6NWD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter STL1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_61425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWD4"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="468" mass="52321" checksum="89F4FF787AFAF3FE" modified="2020-06-17" version="1">MQGTMTSIYNIGCFIGAMSTILTGDYLGRPRQIIVGSTVIAVGAVIQTASYSVAQMMVGRIVAGLGTGMNTATAGVWQAETSKMRSRGKLVIIQMANCITGFSISNWLTLGFSFAPASVDWRFPLAFQIFFSLLIWVMCPFLPDSPRLLIRKGKYEDALEVIAALQGHGATPDSASVRSQFDVIKDILDREHVSTYSWWQLITGRGPSGLLRRMILGAWMQAMNQISGINITSYYMAFIFINALNMTELRSRILAAAGSVDYLIFSCLAYLVIERFGRRKVMMTSAGACSICWIMIAISQGRVAHGGDEYKYGIVSVSFFFVFFASFGMGVLGVPWLYPTEINALEMRTKGASLAMATNWIMNYMVVQVTLPGIENLGWQFWIIWAVICFAFIPITYFFYPETANRTLEDIDRFFETKPGIFVHRNKLAVQLQRPDVYIEADEKFQEAEIAKKSEKDPSYEHVEGKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWL2</accession>
    <name>A0A6A6NWL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWL2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="97" mass="10732" checksum="44807A8196F91B62" modified="2020-06-17" version="1">MMRGGEDVEGRMAGLVWVCLALAGGFGDVPRWSRPRRFPGSRGTKVHEYEIHQEYIQGGHLVPSLGVPAHERTVLEFTSTKAESIDHLEASKQQGMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX76</accession>
    <name>A0A6A6NX76_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_346983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX76"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="20408" checksum="7E01CF51AB8F7C4C" modified="2020-06-17" version="1">MHPWNRPRISRAFPRSRADLIGRGSTVGPASGGYVVVPCLTLRNVVPSCCCRCCGTEGPARIRDHDRSRVRWLDVLPGFGRAVFLPHTSCCAGVRGCGAGPPQTRQGRHCIRRRQRAVRTRVPAVPNCPGCSNAASRRALAFAELASCPPELGGACCPSRCSLRALYPSLRTCRTEHLRLPPPRLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF8</accession>
    <name>A0A6A6NXF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7708 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXF8"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7708" evidence="1">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="48246" checksum="5DB0AD9E5EAF1D9A" modified="2020-06-17" version="1">MLRSTVLHLLAQHHPQYVALAWGTAKFVLVGIINHENLVVQLCQALCNIGDALPRAKITAELYKTDQMKDAISRLYAHILLFFQQAVKWYNRSPAGRVLSSIFKPFELEYKDNLEQIRICAKRVDDTANTAARAEIRDIHILAGLQEKWRAETDRKLLDMQGHHKAISEETRVDVREMKPLIIDIHFKQVMDVLAPKILPEDALRKSQSLVRRGAKFNSVPQDITELLQRIGEWMAKPDSALFVLRASVIALLQPAAPKVLWYLSGPNIQKDTSPATKDVLKSLVFQALKLVPDIVSRNLEHLNAAKMCSEHTEAEWLDLLTAILNQLRKCFIVIEAEDVFRSSSENVEWAATFIGLFQTIVDRAADNGCVVKILVVSYGSAAPRLPNPSNRTVFSVQRPMPVPPHLGRVSRTAAAKTTAWRNLRARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXG6</accession>
    <name>A0A6A6NXG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-CoA hydrolase</fullName>
            <ecNumber evidence="4">3.1.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetyl-CoA deacylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_348102</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O = acetate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="3.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.1" evidence="4"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXG6"/>
    <dbReference type="OrthoDB" id="10250396at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.70:FF:000002">
        <property type="entry name" value="Acetyl-CoA hydrolase Ach1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1080.10:FF:000003">
        <property type="entry name" value="Acetyl-coA hydrolase Ach1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1080.20:FF:000001">
        <property type="entry name" value="Acetyl-CoA hydrolase Ach1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.70">
        <property type="entry name" value="4-hydroxybutyrate coenzyme like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="entry name" value="Acetyl-CoA hydrolase/transferase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046433">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43609">
        <property type="entry name" value="ACETYL-COA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43609:SF1">
        <property type="entry name" value="ACETYL-COA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-CoA hydrolase/transferase N-terminal" evidence="9">
        <location>
            <begin position="14"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Acetyl-CoA hydrolase/transferase C-terminal" evidence="10">
        <location>
            <begin position="333"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="534" mass="59423" checksum="DDEEF5CD34C651FD" modified="2020-06-17" version="1">MSISAALRSRVRRPSYLSKVAQAEDLIPLFPHDSYIGWSGFTGVGYPKKIPAALAEHVERNNLQGKLKYNLFVGASSGSETENRWARNNMIERRSPHQVGKEIAKGINNGNIKFFDKHLSMFPVDLMYGYYTLKKERNRLDVGIIEASAITEDGGIIPGASVGASPEIVQMSDKIIIEVNTAAPSMEGLHDITMTDLPPRRKPYLIMSPEDRIGTPHIPIDPERVIAVVESDYPDKTQPNSPEDETSRAIAGHLIEFLKHEVKHGRLPENLLPIQSGIGNIANAVVGGLASGGADFKNLRVWTEVLQDSFLDLFDSGNLDFATATSIRFSPDGFDRFYNGWKDYTPKLLLRSQQVSNSPEIIRRLGVIGMNTPVEVDIYAHANSTCVMGSRMLNGLGGSADFLRSAKYSIMHTPSTRPSKTDPTGVSCIVPMCTHIDQTEHDLDVVVTEQGCADVRGLSPRERARVIIDKAAHPDYKPILQDYFDRAEFYCLKRGWGHEPHLLWQSFKMHQHLDEKGTMKIDSWETPTFGLPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXQ8</accession>
    <name>A0A6A6NXQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">CTP synthase</fullName>
            <ecNumber evidence="3 12">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_415759</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CTP synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="3 12"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXQ8"/>
    <dbReference type="OrthoDB" id="1739076at2759"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097268">
        <property type="term" value="C:cytoophidium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000207">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000005">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="14">
        <location>
            <begin position="2"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="13">
        <location>
            <begin position="317"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00070745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2456585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="596" mass="65296" checksum="B03754EC41EBD3D3" modified="2020-06-17" version="1">MKYVLVSGGVISGVGKGIIASSTGLLLKTIGLKVSSIKIDPYLNVDAGTMNPKEHGEVFVLNDGGEVDLDLGNYERYLNVTLTSENNITTGKIYKHVIERERHGDYLGRTVQVVPHITDAIQDWVERVAKVPVDDTGEEPDVCIIELGGTVGDIESMPFVEALTQLRRRAGRNNFLQIHVSYIPIIHGEQKTKPTQQAIRGVRSAGLLPDLIACRCERPLEPSTVEKIAHFCQVDVEQVVVVRDMPSIYQVPVLLEDQGLVPLLKDILHLDGVKLDPALVTKGARIWAQWQSLTATLDEHKFHNVDIALVGKYTEFHDSYLSVIKALEHSAMRCRRRLNLVWIDSEALEAPTRDRDPARYYKAWHDVSTAHGILVPGGFGARGTEGMIAAARWAREKGAPYLGVCLGMQVAVIEAARHLAGLEGATSEEFAPAGSPPERHAVVFMPEIDKLAMGGTMRLGRRATRFQPGSEWSRLRALYGGTATHAVLERHRHRYEINPELVARLEAAADGALAFVGRDESGARMEVVELRHHPYFVGVQFHPEYLSRVLDPSRPYLGLVAAASGCLEAVTREVVEGVGGGLAARGMVNGVVDGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXY1</accession>
    <name>A0A6A6NXY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXY1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="19021" checksum="3D5C98CE25727C33" modified="2020-06-17" version="1">MTRRRVHGWSWTTTCWRERGVGHGRIAEGVRPDFEDLQLVKRLQDGRVRAPPHGIVGSTGTGRRAAGPEQEAGPWFDGRAKTRESWWSLPSRRFEVWDRPRLQPAPTGWTGGGRFSRHRPRSINRYREGIGVIESGCWLSLFCYIWASRFYEAETSDFHMGGPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY84</accession>
    <name>A0A6A6NY84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_58137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY84"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="19690" checksum="39C100F94FB71A79" modified="2020-06-17" version="1">MYAGGREASAAAAAAAAAAAAASRRRGGRGAGEGEGAELRGAWRSGRCSRAGKDGPWARRAARICDFPGRRDDGDVLALSGCIVVASAPNPLPPPLAVSAPPPFAGRGGGGGGGRRGASAGGARAPGGEANQLRGHVYTQDSRPGRDFWWSACVVDTTRSPLTVAQAGRPCAAVAAAAASCSLLPPPPPLLLLLLPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZF3</accession>
    <name>A0A6A6NZF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="4">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDY21DRAFT_386278</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="4"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6666987at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01740">
        <property type="entry name" value="GATase1_FGAR_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02203">
        <property type="entry name" value="PurL_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.750:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000005">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000008">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000005">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="21">
        <location>
            <begin position="43"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="20">
        <location>
            <begin position="198"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="19">
        <location>
            <begin position="462"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="22">
        <location>
            <begin position="696"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="19">
        <location>
            <begin position="893"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1309"/>
            <end position="1328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00052585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00057317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF2456872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1377" mass="150039" checksum="CCCDE70A799071C6" modified="2020-06-17" version="1">MSSFGLTRDYATHFALPGSVALSDFRLKRLAQAIGAIDVRAVWIHYVHPSRTLTVDELRSLKVLLHYGETPSPEDRLCQVMLDAISRIGDPRDPNVALFFVSPRPGTISPWSSKATSAAQNCDLEAIVKRIERGMVIAARFDSPIDKDDIPHPDLLYDRMTQSISRTPPDLDVVFGEHDPAQAQQIDLSSSTSPRAAIQQANRTLGLALDAAEIDYLVEAYTEHLKRGPMDVELFMFAQVNSEHCRHKQFNADWTIDGMGKSRSLFGMIRNTHNKHPNHVISAYSDNAAVMQGKPASFWAPSHSTGEWTQTKEVVHYLAKVETHNHPTAVSPYPGAATGSGGEIRDEGSVGRGSKPKAGLAGFTVSDLLLPGFEQPWELDVGKPAHIASSLDIMLDAPIGSAAFNNEFGRPCTTGYFRTLLTKVDILDRESELRGYHKPIMIAGGVGTVRPQHALKEKNIVRPGAHLIVLGGPAMLIGLGGGAASSVQSGEGSVELDFASVQRGNAEVQRRAQEVINTCVALGRDNPILFIHDVGAGGLSNALPELVHDAGLGGTFELREVDNADRGMSPLQIWCCEAQERYVLAVSPEGLEEFKKIAKRERCGFSVVGRATGGETDQEKRLILMDRDSKEFPKPIDLPMSVLFGKPPKMSRIVDSRKLKLHDFDTSLFKYIPTLAEKELLGEAVGRVLKLPAVGSKSFLITIGDRTVGGLTVRDQMVGPWQVPVADVSVTATSLLAGVKTGEAMAMGEKPTLALISPAASARMAVAESLMNIAAASIPDRLDRVRLSANWMSASNHPGEGAALYEAVEAIGMDLCPKLGISIPVGKDSMSMKMKWKDSESQEGKEVTAPMSVIISAFAPVDFTARTWTPALRRLEEVGETVLIFVDLAEGAKAMGGSALAQVFGQTGNEAPDVRDADFIKDFYDAIEQLHEAGIVLAYHDRSDGGLFTTLAEMAFAGRCGLEIMLDDICRTSDPRDLLEGLFNEELGAVFQVRKKDTIEFNKCFATCGPPPGMIKRIGRVSAVSKQHITFTHGAREVYRNSRAALQGYWASTSYRMQGLRDNPSCAQTEFENITDDSDPGMSYNLTFDPKENILPLSAPLFNVFKSKPRVAILREQGVNGQAEMAFAFYSAGFSAIDVHMTDIISGRVSLASFVGLAACGGFSYGDVLGAGQGWAKSVLLHEATRNEFANFFARPDTFSLGVCNGCQFLSRLKELIPGADPWPTFERNESEQYEARVCMVEVMPHAVGQKQSVFFDGMVGSKLPIVVAHGEGRATFPVDPAAGGRPEGLLQEGLVAMRFVNNRLKPTERYPFNPNGSPKGITGVRSPDGRCLALMPHPERTIMKEVSSWYPKEMAQNWSEFGPWLRMFRSARRWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZQ1</accession>
    <name>A0A6A6NZQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_286386</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZQ1"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13279">
        <property type="entry name" value="PH_Cla4_Ste20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000139">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000535">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15413">
        <property type="entry name" value="PH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="67"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="14">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="572"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="249"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2457186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="862" mass="94460" checksum="FD9B508695743E8A" modified="2020-06-17" version="1">MYAPGQFMNPGPAPRPPTDRPRLNLTPSVNNLPGNMSGLSMQSPSANASTTSLARTQSEKSSGSSSPVIKEGWAKVKEEGIVKGMFWSDKYLILREFSLDFQKSNSGKVSFTIRLGDVTNITRSENHPYSFEIARTSGSAAGQSSPPRDGPTKVLICKVDTDDEVYSWIDCIYQRCPSMGGVSNPTNFTHRVHVGFDPISGAFIGLPPEWEKLLTASAITKDDYQKNPKAVLEALEFYTEKLVKRSEDPAAYPSLTPTPPADNSSNTKQLGYGGGGGGGGGTSIAPPRPQPPNGFQRKESYGPSRADAVRAETPPGQYISASEKAAAYQQAQNDQRRRERERQRERERQMEYERQEAERREREEQAAYNASLPRQRTPIAKQEVAGYVGEDTRDSSPSSTPARYNPSRPAPSTPSSSRERQQPSGSLRQMTAQRPAPSAPTGAQNKPGQMKPPTSSAQRQPSPNARYAPGANAQSSQPSTRAPNGAGVQSSTRIPGPSGAAAPKPLNVAPKQQQAPADGAPAVDPVKKAEQMLTKKEDQQPRKDVRMSNMSESEVMARLREVVSRDRPLDSYNKQKKIGQGASGSVYVARIRENAPSSTARSLVRDNGPRAQVAIKQMDLRNQPRKELIVNEIIVMKDSKHPNIVNFLDAFLQEEQSELWVVMEFMEGGALTDVIDNNPSISEDQIATICLETCKGLAHLHSQNIIHRDIKSDNVLLDARGNVKITDFGFCAKLTEQRSKRATMVGTPYWMAPEVVKQKEYGSKVDIWSLGIMAIEMIESEPPYLNEEPLKALYLIATNGTPRLKKPDKLSKELKAFLSVCLCVDVKSRATAQELMNHDFLKSGCSLASLAQLLAFRKNGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P038</accession>
    <name>A0A6A6P038_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_35664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P038"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025353920" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9223" checksum="8D37E890FCE56C64" modified="2020-06-17" version="1">MRWHRRLVAWFMLRSGWFLRGSVVSLFASRRGDGNSEPHQKSFGGIYGAHADILHEVKALITSSFVAACLLGPRIDGTVHSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P058</accession>
    <name>A0A6A6P058_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF410-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_35149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P058"/>
    <dbReference type="OrthoDB" id="10252405at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="35787" checksum="FF96E0414A179AFE" modified="2020-06-17" version="1">MSSKIEKTIARQQQRISEGQFYEAHQQLRVIASRYAKASNWAAAVDILSQGAAALLRADQGGSGGDLCLFLLDVYKQAEMRPDAETKGRILGLLRMFPKGEPTRKRVVGEMIGWSSRFGEYPAGDPELHHVAGTLYADEDEPYEAERHLLLGTRDSPERLTKLLFAWYAESGSPSLAASFAARAVLPYLAVGNVRAASKSLLLFGASLSSSPSPPPVQDVSSATAELRVYPSLPLMNFLGLLLQSVQRGDAGLYRMLRSRYDDQLREVPEWEDVLGQIAEMYFGIRKPSQSNPLFDMMSSMLMGGGSSGGSSQGAQRRVGAGGPPAAGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P190</accession>
    <name>A0A6A6P190_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">BDY21DRAFT_284996</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="29" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="29">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 22">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4251012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.20:FF:000005">
        <property type="entry name" value="Fatty acid synthase alpha subunit FasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2490:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.25.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026025">
        <property type="entry name" value="FAS_alpha_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000454">
        <property type="entry name" value="FAS_yeast_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 24" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 24" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 22 25" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="27">
        <location>
            <begin position="146"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="28">
        <location>
            <begin position="1094"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="99"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="1327"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="26">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="26">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="26">
        <location>
            <begin position="1330"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="23">
        <location>
            <position position="1280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1749"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1750"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1751"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1848"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1849"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="25">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="KAF2457726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1862" mass="204230" checksum="B4821E1543430B46" modified="2020-06-17" version="1">MSPEVEQELAHTLLVELLAYQFASPVRWIETQDVILGDRKTERIVEIGPADTLGVMAKRTLASKYEAHDAALSVQRQIYCYSKDTKDIYYDVDPVEEEAEAAPAPAGDASSSAPPPAAGAPAPAPAAAASPPPSAGPAVAVPDAPVSATDVLRTLVAQKLKKPLMEIPLSKAIKDLVGGKSTLQNEILGDLGKEFGSTPEKPEDTPLDELGASMQPTFNGQLGKQSSSLIARMVSSKMPGGFNITAVRKHLETRWGLGPGRQDGVLLLALTAEPANRLGSENDGKAWLDDMANKYAANAGINLSTAAAGGDSGSGGGGMMMDPAAIDALTKDQRALFKQQLELFARYLKMDLRAGDKAFVAEKQSAAALEAQLDLWSAEHGDFYATGIEPSFNPLKSRVYDSAWNWARQDALSMYYDIIFGRLKAVDREIVSRCITIMNRSNPRLLDFMQYHIDHCPTERGETYELAKELGQQLIENCKDVLNESPVYKDVAMPTAPHMEIDARGNMNYSEVPRPSVRKLEHYVREMADGGKLSEYGNRTKVQNDLQRIYKLIRQQHKMSKASQLQIKTLYANVIRSLSMNEGQIIPHENGKNGRKNGRNGRISGKQGKVETIPFLHLKRKDDHGWEYSKKLTGVYLDCLEQAARAGVTFQGKYALMTGAGAGSIGAEVLQGLISGGAKVIVTTSRFSREVNEYYQQMYARYGARGSQLTVVPFNQGSKQDVEALVNYIYDDKKGLGWDLDYVVPFAAISENGREIDGLDSKSELAHRIMLTNLLRLLGCVKVQKQERGFETRPAQVILPLSPNHGTFGNDGLYAESKIALETLFSRWHSESWGSYLTICGAIIGWTRGTGLMAGNNIVAEGIEKYGVRTFSQQEMAFNLLGLMAPAIVNLCQVEPVWADLNGGFQYIPNLKDVMTELRKEYMETSEIRKAVTKETAIENKIVNGEQSEDLYKKVTVQPRANLKFDFPNLPDWETEVQPLNDDLKGMVDLEKVVVVTGFSEVGPWGNSRTRWEMEAFGEFSLEGCVEMAWIMGLIKNHNGPLKGKPYSGWVDAKSGEPVDDKDVKVKYEKHILDHSGIRLIEPELFNGYDPHKKQMLQEVQIEEDLDPFEASKETAEEFKREHGDKVEIFEIPETGEYTVRLKKGAALLIPKALRFDRFVAGQIPTGWDARRYGVPEDIIEQVDPVTLFVLVSTAESLLSSGITDPYEFYKYVHISEVGNCIGSGIGGTSALRGMYKDRYLDKPLQKDILQESFINTMSAWVNMLLLSSTGPIKTPVGACATAVESVDIGYDTIVEGKARVCFVGGFDDFQEEGSYEFANMKATSNAEDEVAHGRTPREMSRPTTTTRNGFMESQGCGMQIIMDARLALDMGVPIYGILGFTATATDKIGRSVPAPGQGLLTTAREMPSKFPSPLLDIKYRKRQMELRRAQIKQWQEAEYMYLQEEVGAMKSADAGFDATEYVEERTGHIDREARRQEKEALNSLGNNFWKQDPRIAPLRGALATWGLTIDDLGVASFHGTSTKANDKNESDVVCQQLRHLGRSKGNALPGIFQKYLTGHPKGAAGAWMFNGCLQVLNTGLVPGNRNADNVDDALEQYDYIVYPSRTIQTDGIKAFSLTSFGFGQKGAQAIGIHPKYLFATLDKAEYANYRGKVAARQKRAYRFFHDGLVSNTMFRAKAASPYADALQSKVFLDPAARVAPDARSAELAYPAKPAPPSAAEARRADETRRVAETLAAAQGGADRRVGVDVESVDAIPVDNDTFLERNFSAAEREYCAGAPDPRASLAGRWAAKEAVFKALGVASAGGGAPLVEIEIVAGKGGPRVVLKGEAERRAREAGVREVSVSISHGAGQAVAVAVAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P198</accession>
    <name>A0A6A6P198_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P198"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="230" mass="25841" checksum="C05362CC99565E92" modified="2020-06-17" version="1">MPVEPDMCRGIEMYSAEWRLISALEPLEVASEDHNRVMKVLRQWNWQWMQKKAIEVLWDHGSLCHSLGRISLSDVQQTPEEQEQPETPENSEAQESEAPKNLVVQEESEVEQAGDEGSDTEVDSEVEGKGSVELSDELTCPGVQSGEGEYLPRETHTRSSGAPWPAGIEFHHGTVPLSLEELTPLAHCADAGSNGESTFEIETKTRPRVRDILSRYERRMPSPVEPRQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P215</accession>
    <name>A0A6A6P215_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_285455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLT11 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P215"/>
    <dbReference type="OrthoDB" id="10259600at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12265">
        <property type="entry name" value="RRM_SLT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000396">
        <property type="entry name" value="Putative Pre-mRNA-splicing factor slt11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034356">
        <property type="entry name" value="Slt11_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048995">
        <property type="entry name" value="STL11/RBM22-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF6">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21369">
        <property type="entry name" value="STL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="239"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="156"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="386" mass="42624" checksum="54EBDFEECB20C352" modified="2020-06-17" version="1">MPPQVKHDVNRSGHESTDFPSVCERCLPDNPYVQMLKEDYGAECKICTRPFTIFRWKADRTSRQKRTNICLTCARLKNCCQCCMLDLSFGLPIVVRDAALKMVAPGPQSAINREYYAQVHEKEIEEGRGPMDAYEKTDEKARELLSRLARSEPYYKKQRRLEEAETSEGGQKALPAPESSSGPSHLPGPMRTRDTREFARLRGYRGARRGRGGRGGRMGLPSIEPTPQDILPPTDPNITSLFITGVEDDLPEHEIRTFFTQHGQLRSIVCSHRAHCAFINYATRQGAEAAAEACQGKAIIKGCPLRVQWGKPKPLDTMEREQRLAYAKEGRAIAGNRRARDGSTAEGAGALAEQPAAAENDLDSLAAIAAPPGADDNVKYASLAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P251</accession>
    <name>A0A6A6P251_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_18277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P251"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="114" mass="12448" checksum="5CB92535DDA2685F" modified="2020-06-17" version="1">MIQAIGTYTAVALLFHLSPFPFLCFLPWAASALFRAFSGTSGELGVLRMQGDEYCVGRAAAAGPAPPQQVDSPFFVALADVECFRARRFEPRPSSNRPVSFEVCIAQPMSLWSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2B1</accession>
    <name>A0A6A6P2B1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_285259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2B1"/>
    <dbReference type="OrthoDB" id="5334244at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="170" mass="18271" checksum="AEDCA430AFB2B4CF" modified="2020-06-17" version="1">MPSTRLVPPLLLLRPAALRPPPVLAVRPRQQRLRALATTAPRLATQGHGGGTPAGLRAPRQAATPAEPGEHPGPAAARAAGGGRSEESAPGRARSYATSSKKKKEEKDLPGGEHPQPKILHDDPPAGEEQPEDVKRHNEELERMPERAKMRVDNEDAEKDKVPAGFWSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2N3</accession>
    <name>A0A6A6P2N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2N3"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13359" checksum="F00E7E0E2010DFF4" modified="2020-06-17" version="1" fragment="single">MPEQRNIIVLGASYAGLGSMHYIMKHTMPALAATTDGKDITYHAYIVSPSRDFMARPAAPRYIADKDLLGGYGKLFKPLSGALEQYPKDSYTIVQGSATAWDPTARIVTVTPTAPDAGAGGEQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2N9</accession>
    <name>A0A6A6P2N9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_284527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2N9"/>
    <dbReference type="OrthoDB" id="2104739at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="190"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="44508" checksum="8B6E79D0E2DFCE5E" modified="2020-06-17" version="1">MALPLHRHQSSLEGLINFSTEPPLEAGRRAKARRRFYQIVNHFEPIDNDNSSNNNNEYNRPRLVRLTYEYARSEESKDNVLRAFFQSMLLPINSDEDIDFTDKNLEDEVHSTLIGFADYLVDNFFLPLKASTRKTPQPSPIHHSAVQGAQGGTQEFTGTPARISALRGSCLIRDRHRCVVTRIFNAAEAENRTISRGSSAQDDDGNSLIEESRFEDLEVAHILPHSLMKVAADSESENAKQATRTILNMFDNGVVYLIEGTEIDRPRNAITLTPTYHRRFSDFRIFFTPTADQQSHTYRIDSFLPPSILQGSLPVTRTLYLTETRTIDPPSPQLLAIHRAIAHILHLSAAGKYIDKILQDIEKHSIRADGSTELGRLLNLGLRGWLKDTVDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P363</accession>
    <name>A0A6A6P363_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase signature domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_411588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P363"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="161"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="642" mass="67909" checksum="47C0062EE5DAE4DD" modified="2020-06-17" version="1">MAADKQNGEQHQQQEQEEDVKWINYPTPELVEDVNFTPIPPPKNPVIRGYALQIGASVICALPPIQTFLYNNTSFGSTLASIPGIDALPPTFYPAVIPSPASFSSSTPTTSSPLPFAAADLRPAPAVDPTTRYWSVGDYHAAYVSGCLTPSAVVEFLLPQVDRSASAHRSTHAVAFVQTRADLARAAAAASTERFRAGKARGVLDGVPVAVKDQVDIRGYGTTMGTARDWCNGGKGGEKGDEGETSWCVRMWEEAGAVVVGKTNMHEIGLDTTNNNPNLGTPRNPFNPNYYTGGSSGGSGYAVATGLVPIALGCDGGGSTRIPAAYCSQFGLKPTHGRVSISPSVSLAYSTSVSGPLAANMTDLEAAWRVMCTPDPGEAVSELFRAPRRPSPSAGEARPKLLGVFRDWVDRADPPVRKLFDAALAHFTTRLGYAVVDVGIPLVPEGQAAHALTILSEVSSVWAAPDRAPVLAPAGRVLVAVGARIPARDFARAQKLRTRLMRHLAALFARHPGLVIVTPTTPNAGCHIAGGEADLRRGVSNGNASVRSMEFTWMANLLGLPGLNVPMGYVEPVGGEGGEVPVGLMGMSEWGKDDELIEWGFDGERFLHDGLEGGRKRPEGWVDVLGLAGEKMRESVSGESQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3V2</accession>
    <name>A0A6A6P3V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Heavy metal tolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_385452</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3V2"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03253">
        <property type="entry name" value="ABCC_ATM1_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000186">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000050">
        <property type="entry name" value="Vacuolar ABC heavy metal transporter (Hmt1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF651">
        <property type="entry name" value="HEAVY METAL TOLERANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="587"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="354"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="674"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="925"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="925"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="939"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="952"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="976" mass="108871" checksum="2CF672FEB3253B76" modified="2020-06-17" version="1">MLPREPLLERLHSQSASPAPPFTSSPSSSSSAAVAPSRSAAHAVLVDLHFAYPIVLLFFFLAAFTARSILVSNRNANRPNQKLQLGPGGKPLPKLDPTRNHRTRKEKPDDLPRSQKVVFILLSALAAASFLANAANVIIHALWRRDQEWWCGQHMVIYVCGSFFVYTLFLISISDAKPSPNSAHLLTWLLCLAMELVLFAASIAVYTEKHHEPRVGDPFGGRLRYNMTLWEIIEVTIDLLRIVLIVALLGLYGLFVTAFKAAKRERDAQSPSETSSLLGDGPRENGQNGSANGYGSTGGRPVGGKHAHTEGEPAGWVRPKEMPSRSWWEYLKGYSVFFPYLWPSKDRKLQITVIVCFTIVVLQRAVNVLVPYQVGVITDKLSGEDGPVQMPWIPICLYVVYRLLQGSNGLLGALRSTLWIPVGQYSYRELSVAAFEHVHGLSLDFHLGKKTGEVLSALGKGNAINTFLEQVTFQVVPMLVDLGVAVAYFLVAFDAYYALVVAIVTFWYIYLTIRLAQWRAEIRRHMVNADREEDAVKNDSMVSYETVKYFNAEGYEFNRYRDAVDKYQKAEYKVLASLNFMNVTQNLVFMLGLMIACFIAAYQVTTHQRKVGDFVTLLTYMAQLQSPLNYFGTFYRVIQSALINSERMLELFKEQPTVVDKPTAKPMQSCEGDIQFNNVHFAYDARKPALHGLDFGCAPGTTTALVGESGGGKSTVFRLLFRFYNAQSGTIQIDNHNVEDVTIDSLRRHIGVVPQDTVLFNESIMYNLKYANPKATEEDVYNACKAASIHDKIMAFPDRYESMVGERGLRLSGGEKQRVAIARTILKNPRIILLDEATAALDTDTEEHIQKQLTTLAEGRTVLVIAHRLSTITRADQILVLEKGKVVERGTHLELLAKNKRYANMWKKQVQAQQVAEQARVLNDQADRLRRESKDVPMRSSSGESSRASSAQTGSLDGSTSGQDGRARPNAAARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3W5</accession>
    <name>A0A6A6P3W5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_214157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3W5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="25136" checksum="637A4C97372A0803" modified="2020-06-17" version="1">MCKEVHGNMAFPTRQEALPPRQRGCQAQVGLLKVCWHTTLGWNDSKKICLESRKLAEKGDSNNPSQVIHFPLCHHPDHKDENNVDGKLWENAPKVYVDQEAKKSHIFLEFGLVRVAPNDTVDRQKFRDAQSAYKGRKICPHEKLSDLNLFRQYREVAPAGLRESVFAPCRFCDTRYCVRRCRVTDDPQDNHRVSLVVGRGNVVDWRNLKESWDKITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y2</accession>
    <name>A0A6A6P3Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Endoplasmic reticulum vesicle protein 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_385044</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Y2"/>
    <dbReference type="OrthoDB" id="759142at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025344608" evidence="9">
        <location>
            <begin position="24"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="40"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="220" mass="24872" checksum="EE2846ECBDB4EDA8" modified="2020-06-17" version="1">MECLSRFLRLLLLALGAAQLAVALKFDIQAHPGHESSKYERCIRNFVAKDQLVVVTAIVNGQRGDGQMLNMHIRDAVGNEYGKPKDVVGENRFAFNSHADSAFDVCFENVLTSKRDVMSPTRHIELDIDIGADAKDWSAIQAGEKLKPVEAELRRIEEVVAEIVSEMDYLRGREQKLRDTNESTNERVKWFAFGTMGMLVGLGAWQVVYLRAYFRSKHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y4</accession>
    <name>A0A6A6P3Y4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_410541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Y4"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF16">
        <property type="entry name" value="BACILYSIN BIOSYNTHESIS OXIDOREDUCTASE BACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="416" mass="43443" checksum="9BB6703B7471302E" modified="2020-06-17" version="1">MRIERRRLHSIVMAEEPKPLCSPPLKDLDKPWDPSPIRGLTILITGGASGFGAAFAREWAKLGATVVIGDVDDEKGEALAKEFQGEGQEEEEAAAEPAKGASQAAEKGRIHFLHCDVRSWESQAALFKEAIRLSPHGGIDTVVANAGVARPDCLLKPPARTDPATGAEEPLPPDFLITDVNAVGALYTAHLALFYLPRNPGSAPATPWTSSSSSSSGSGSGSTSPAAATAGRRDRHLLLVGSVASLMPVAGLPQYCAAKHALVGLFRALRLTAAGGGPGVRANMVCPYFVDTPLLTRGARLLLAGGALGRVEDVLDAAGRLVAGGGVVGRAVVVGPRGMKGSAGPPGMGVGAAEGEDAEGEVVECALWEAYADDWEVSEVWNRGVIRMINRVAAVRGWIGWAGDLWSAFWARDSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Q1</accession>
    <name>A0A6A6P4Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_414545</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Q1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000053">
        <property type="entry name" value="BZIP transcription factor AtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021755">
        <property type="entry name" value="TF_Aft1_HRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021756">
        <property type="entry name" value="TF_Aft1_HRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020956">
        <property type="entry name" value="TF_Aft1_OSM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11786">
        <property type="entry name" value="Aft1_HRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11787">
        <property type="entry name" value="Aft1_HRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11785">
        <property type="entry name" value="Aft1_OSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="499"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="336"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="622"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="638" mass="65212" checksum="FF0A75B33A5A00EC" modified="2020-06-17" version="1">MAAAATTSSTSSPHLSSRMSSPKDSKRNNPLKADDKQRASPLRNSQETSQPSPPRSDAVQPVNGSQDSGDPKTQTSTANAQPLAPPPRPSQSNGQDGGDYFSSAHANSHFQLEPNPFEQSFGNPSSAETPGKSLLPPVASLTSPSSLLPGGTPTWQNSLRSGPLSPAMLTGPTGPTDYFSDNHFRGSFPTPNESSLRTGLTPGGGGSMFPAPSPNSIFNQLQSGGATPSTIDFHRTAMSAAARNNNPTSAAGGPSQNGATSQSQDVGLQPVTTTSMDSKPFAAPQAPATSGPTQHPPQAAADPFGQHDANDAANGLFLLAQANGARNNPGFGAMPGQQQQQQQQQQQQQQQAGAGGAVQSVGGAHQQLEQTSPVMGGGRQRNAKGSVVSTAESESGHSEAATVGAGAQQKRGGAKGKKGASGGAGAGAAGKAQGGAGGANRRKAEDAPKGSANKRAKGNSGAASVSAGEGHDDDDDSDEDGSMKAEGDGQQGNKKMTDEEKRKNFLERNRVAALKCRQRKKQWLQNLQAKVEIFSTENDALSATVTQLREEVVNLKTLLLAHKDCPVSQAQGLGGMNMNSFIGDLNHHANPYGMALPPNGAAAAAAMGGLPVGAGGHHQHGHQGAQQQGVPQGLGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P517</accession>
    <name>A0A6A6P517_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sister chromatid cohesion protein Dcc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_370410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P517"/>
    <dbReference type="OrthoDB" id="5199543at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="371" mass="40189" checksum="E5E9ADA4FFDB32D3" modified="2020-06-17" version="1">MSTQQSEHSIPFSLATTQQPLRLLELPPSLLDVLTITTSSSTAPTLYIKSAGPRTTPPVSAAGISAARNAVLCAPRHTFSLRQVHTSNSVLVARPCGAAGPPQPAEEPGLRAVACCATTLELLPPHEGNEAQAEPEMYLRELLPVYEGPGAEADGDADMLDAETEAPGLRISKADAFADVPLSDEECEDGWRALCAFERGDAGAYRPAAGALLEAWKDILTASIAEGIEWGKQFRVGALWAVIEDENVPKGLFDGILRAITGGEFTWTWCAVEKDRCVPWVGKVLLEYRAPKSPGILTAKFLDEWKDYVPEEWRADVALELIKNKYTTPSSSTIMYQFQPMTKEKATAAATGVKPGAGARKWHEKFKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P543</accession>
    <name>A0A6A6P543_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inhibitor of Apoptosis domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_205900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P543"/>
    <dbReference type="OrthoDB" id="2196114at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051190">
        <property type="entry name" value="Baculoviral_IAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771:SF5">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="559"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="485"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="567"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="628"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="830" mass="91606" checksum="D144DEE4D2BBFF08" modified="2020-06-17" version="1">MSSPPADAHTFAGRLATFQVPHANKRRGSATSKKKSPAVLQWPHSKPTPEDLARAGFFYRPLAGNPDNVMCFLCLRQLDGWEEGDNPAYEHLAHGPDCPFAINVAIGQRVEDSERDEEDPMSQKMTDARLATYLNKWPHESKRGWKCKLEKMVDAGWCYDPSPEYDDGVTCYYCMLSLDGWEPKDDPMEEHRKRESDCFFFELLGKYGTTRKQTKGKSKGKGRASRTSKASQTSDAPRSSNIDFTNLSFSEPPTLMSLGEYPPGQDDSVMTTATNATGATIASATGKRKAATKTKATAKGTRKGGRAKKKAASPELEPELEPVPEPVPEQPAQEKLLHEEVVEMEDEPTQIAPPTRRATRNSKNVGDSSMIDTSLANSRSQPPRATRAKNTRAKAQKRMSEDEFQLHTELKDAVRRASDQSDASRTRGTKRTSDGAPKTADSSVAILDEPSQLPTKPPKRARTAKKKAAEEHEPNDEASFDKSTTRAAKPAAKPAAKPATKGRKGKKAAKAVEADVSKATEDQMKVDSPPRPFDGRPTLRPFQPEDWEEARREAMEAVGRPVTRLSFHHDSSEVVEEKPRRGPFGGKPTLRPLTPYDHEPSSEAAPHVEEEEPERPATPIIAEEEQVPAEATPTPTHPASHNTARIAHFTPVHRPSRKTASRSPSQQHSDAENQPPSTRPSAQRPPLSVSRFNVPSSVKRTPLATCTPLPSKRNAVEGRLVSSVPWTAIDLENVFIPSPESKRLFDESAGLMGMLASPDKENRLPLDQVVKNVKAGLTSPEKKMTVEEWIYHNASKGEERLRNECERMVSMFETKAGEALRALEGFETPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5X3</accession>
    <name>A0A6A6P5X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 76B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_340111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5X3"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="334" mass="38303" checksum="17A39A2BE68183AC" modified="2020-06-17" version="1">MESRDDELFDEITEVEDEISRFRSTTGNLQDYVAVLRWDPRSWLGGGWGSARAREMRRRRDVYLKKLNDDLDERIRNGTYKPCIQANVILDKEARLNKEELTSISLTMLSGGLDTITTLVAWAIALLAQRPDIQEKACGEIRQMYGEEQALCDAYDDQKCAYVVALVREFLRFYTVLRLALPRATVRDIVYEGVRIPEGTTVFLNAWACNMDAAIWPDPETFRPERWLETPDAPLFTYGLGYRMCAGSLLANRELYLIFMRVLNAFEIVKRTDVDAHPVSGSADPTSLVTMPRRYEVVFRPRNERALREALTRAEGEAKGQEKEEKEKEKVGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6B8</accession>
    <name>A0A6A6P6B8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase C15, pyroglutamyl peptidase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_187749</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6B8"/>
    <dbReference type="OrthoDB" id="407146at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32361" checksum="634A7C228926E54A" modified="2020-06-17" version="1">MNTAEGVASASSGHDADEVAVLVTGFGPFLNNSTNPSWLIASTLPAHLPASPTSHPSTPRINILVPPRPIRVAYRAVLATMPAFLASTYAAADVVLHIGLASGRSFYTLESRAHRDGYRARDVDGEGWRDEDSWARWGAAGLPEVLASGFDCADVWRRWREAVDRVEMEGGEGAGAGAGAGAGEAGGEEGKSGLDVRPSDDAGRFLCDFIYYTSLAWFADRSAKEEEEEEEGEEEDGGQDGTDPNRATIGNKPLERPVAFLHVPDLPTEDDVEKGRQVTIALIRALVESRRVTIEKRRSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6E8</accession>
    <name>A0A6A6P6E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_192664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6E8"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039340">
        <property type="entry name" value="Tfc4/TFIIIC-102/Sfc4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="929"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1095" mass="124053" checksum="ACD16194546FB564" modified="2020-06-17" version="1">MAHDDGNQWSTMEQRVGQDGSTLSFTGPYPAIYGSTSYDHIEDAHIRALPSFGSGGASDSLNRSIYPDLPSESDSDSDEDGFDLPDMEDEQDDEDFEQDHEQDIVMDDPVSDDPDYTLLDPELEESDEEFSPSDEEPTGDGRRGARRGGRGRGRARARAIHVRPRKPFPRGEGPIGSKKGKRGPQAAADPNPNFKRLHSLATNAFINGNFDEAVGHARQAVQENPEIFAAHGLLSEILLAAGNKAEGLESLTYGAHTKRDPGLWWHIATETLELDDLDKNEKLRKADYCYRQALKLDKHNFDARMERFKMNLELGRFGSARTQCERMLKLRADDQEVLRLYTELCVKTGDSAKAIALYDQRIDMLIDSEYTGNERMDWSLLNVYLDLLIHSGRFDTGVRQLSTLSRWMLGRKGDTLWDAVNDDREWDVNDERRIKTEGFEPNRYPNQAYGAGLPIEIRVKLGVLRIRMRPSYYPEAMRHFELLNPSAESSHSHALEYQDLFREAADALRESGFYEDALRYYSPLQKFGPHTSIFYLSLLECHSLLGNISEARALFDNVLQHENGNVKARVLMAKMYQKADMSESGLSIIRDLIRIGKRDVVRKEGLAVGQDGWMLRSTYRRRRYGPRGPYGPRKTKLVDGTQPSKAGTIRMALDFPSQDLWKRLKSLKDVDKDEDDETAAEYIGLTQKLVAEFCENRQFFPRDRSARTSAFARFVDTIDYEDDDGANGDANADNGDISRISEAAIENPEHTSHEEGTAANSLQLDSEDFQGVSFETLLDAICESAWRLAKAGRASECWEMLMNVAQSLVFDRSPQLSFRLRITILACGILLDDDDQVLNTSRWFIRRFSHSPDSFRLYTSAIRHNLAESSKINLGPSQKFILRHLKAADFAVLNSEQRNMFEFTSIERSSWTNRGTTDGNPSKLKELDPTVIVCYGHILAHSGAYPSALNYYFRAFALTPDDPVLNLSIATAFVQHGLRRQSENRQFQIQQGLAFLRRYYEIRTKDNVPIHVQEAEFNVGRMWHLLGLVHQAIPAYKKCIMIGPRAAADSLGDLPEESEESEDFAAEAAYALQFIFCMGGDTETARQLTERWLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6F8</accession>
    <name>A0A6A6P6F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flavin reductase like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_370195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6F8"/>
    <dbReference type="OrthoDB" id="2015405at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050268">
        <property type="entry name" value="NADH-dep_flavin_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466">
        <property type="entry name" value="FLAVIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466:SF1">
        <property type="entry name" value="FMN REDUCTASE (NADH) RUTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="30158" checksum="E040C10642319B68" modified="2020-06-17" version="1">MRSLPYPVVIITARDPSSPTTTSPSPPPSTLHGMTVSSFQTLSLTPHPLVSFNVKLPSHTHAALQAAGCFRAHLLAATPVGAALARRFVNAGSASDPARPWLPFAGLAAGPRPPDARSRAGRASRAARWDLPASPLAGARAAPKGRECPSSSPSPSPRCPPRLSGPAVLADFFCEVLPGKCVAVQDHVVVVARVTEVRVPVGERGGEGEGRVAGGPVEVRLEAERLLARDARVELGLVYGNRTFRGVGGVMREAENDDGGEGDAGGDDGQDGVAPHYVLRMERGDGEDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6G0</accession>
    <name>A0A6A6P6G0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_362290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6G0"/>
    <dbReference type="OrthoDB" id="20729at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051767">
        <property type="entry name" value="Nucleoporin_NUP42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527">
        <property type="entry name" value="NUCLEOPORIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="473" mass="50619" checksum="729F70DDBB20C613" modified="2020-06-17" version="1">MVVCKFFLQGNCKFGKNCRFDHPTGGGAQNWAPNQNAPRGPPQGQSRSQNQSQTQTRFGQPQPQHDVFRGPQSRNQPRGGNRRDARDLPLDNLPYLIVPDAIETDLRFERPLWPCSAYGPGRDAPRQLFGGYPIELSPEELRAMFYKGMSQGDTAQAIQLEKEADDRVQQHIHSVLRDIPGACRYIIDGEHEHPNRIDICKATTSGRQQSNIPGGDAAFMRSTPTASPGTSNLGVARSGWPAPIGGTQQQGGVVGFGHPSLVQAGPASGGGFGAPSFPTSQPNQQQQTSFLPQGQTLGTFQSSSPFDTEQSAFQVPSGPTSFGVLSGPNATAVGPSPFSRPAQPGTFGPNPFANGFSQPSAPIGPLPAQNAAAPMTNGATGGETTRDARTGKLSTWHGEPVQYIDGKPCRREGNDWKRILFPDGPPSPVQGAYGSNHTEEEKAAYEAARAAGSFPNGIIPLEPPSWDMLTWDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6L7</accession>
    <name>A0A6A6P6L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-ubiquinone oxidoreductase 213 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_194491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6L7"/>
    <dbReference type="OrthoDB" id="1913277at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039205">
        <property type="entry name" value="NDUFA11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="194" mass="20657" checksum="77335A9423852E76" modified="2020-06-17" version="1">MASEEQPYQPRDVIDRTIKAVMVVGGAGTVLSAIQNSLTRQNVGALGFITRTGGTIGTFAALGAGYAFTSTAAANLREKDDAYNEAIGGFFGGSVIGLSKRSFPKTLGYGAGLAIVLSAFKYTGGGFSRHGKDYTKDNVEAKDALRNAKRIPMEQTLSEIGEGRGIYPEGYEERRRARIKEKYGIDLSGVPPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6N1</accession>
    <name>A0A6A6P6N1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_414041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6N1"/>
    <dbReference type="OrthoDB" id="48057at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000016">
        <property type="entry name" value="Oxysterol binding protein (Orp8), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF212">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="50741" checksum="E687F848A1EBC5A0" modified="2020-06-17" version="1">MASTKAEAASSLSPAAAAGSAAPSSAASSADPSRAPTPANAPVEKTPDESSKLKTFLSILRRFIGVADIASVRFSLPAQLLEPTPNLEYWNYLDRPEMFISIGDSEEPLGRMLGTLRFWFTKDLKYVKGKPCKPYNSTLGEFFRCNWQVEDTAPSISPPSSSAASSTGNRTVKVSYLTEQTSHHPPVSAFFVDCPEKGIIARGFDQISAKFTGTSIRVTPGAHNLGIFITLQRWDNEEYQLTHPAAHLGGLLRGSLSVTVADTCYVTCAKNKMKVILQYLEEGWLGKTQNKVEGVIFKYDPANDDKTRIKDVPDKDVLGRVEGCWHEKVYYTVGNQPFSKAKEKHLLVDLSPLWPVPKIVPPQTEQLPNESRKFWSGVTDAIVSKQYSLATQLKHDLEERQREKAAERKEKDFNWKPRFFTGVTEPTGKPGLTPDGEVVLQGLHKDEYNLKENEVYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7V2</accession>
    <name>A0A6A6P7V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_337386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7V2"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="64" mass="7011" checksum="81F2417DBA7F3A7E" modified="2020-06-17" version="1">MSCKICFEQLANVVFQDCGHQMACSWCAEQLIGVPQMNVAGFLVRPRCPVCRAEISGVVRALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8F2</accession>
    <name>A0A6A6P8F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_369314</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8F2"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="5">
        <location>
            <begin position="51"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="424" mass="46827" checksum="D110FA83780ACE55" modified="2020-06-17" version="1">MPSFVPVGPAPNEGQPGLSTEFFNGNGIWRDAPVLRGTTKFRPLPEVKSIMITGGAGFIASWIARHLVTSYKETYNIVCFDKLEYCASLSNVGALNSYANFKFVSGDITNPTDVGRCLAHHHIDTIFHFAAQSHVDLSFGNSYEFTETNVLGTHVLLECAREFGIGRFIHVSTDEVYGEVAADDTGLLEKSILAPTNPYAASKAAAEMMVNAYSRSFKVPAIIVRSNNVYGPHQYPEKVIPKFACLLHRNQKLLLHGDGKHTRHYLYASDAVDAFDTILHRGSIGEIYNIGSRDEISNLTLCAKLIGVFGHTNTTEKDVYAHVEHGCDRPFNDRRYAVDGSKLKRLGWTQKTGFDEGLRMTVDWYRKYGDVWWGNIEHIFAAFPSAAKEQSSPGGECSSAPSSGARSSLDEAWTDEVKTIAENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8M1</accession>
    <name>A0A6A6P8M1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar ATPase assembly protein VMA22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_160257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8M1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990871">
        <property type="term" value="C:Vma12-Vma22 assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040357">
        <property type="entry name" value="Vma22/CCDC115"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21730">
        <property type="entry name" value="Vma22_CCDC115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="22425" checksum="BDE19CB60649ACD9" modified="2020-06-17" version="1">MKTKGFFSLAQANFNHPHRSRYGQDYYDERMQAQRRVEIEPSSSDKSLRIHKFGSAFTTSQPTSPTSEPKDSSTAYPSQPPSHSLASTPSMDSPSESLESPASSIPDEKLPPSPTRLPPDPIRMFGILVPPALRAAQASFSAGVDESLGELASLTVQMRRLEGEIARSRKGIKRAERAAVDGQDGKTGSEGDRVLLEGLRELKVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8T8</accession>
    <name>A0A6A6P8T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dip2/Utp12 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_369396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8T8"/>
    <dbReference type="OrthoDB" id="30195at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="307"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="444"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="505"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="589" mass="61273" checksum="BBB87294F7988E0E" modified="2020-06-17" version="1">MAGPLAPSSQKRSGPATTNSSKVAPKYAPRSVTARKAAAPAPAKAKAGRPTGFAALLDGKANGLTARTTNGITGSRPDPTGNARMVVGRGDMVSDSEEDDNENSADERAGKTQVGAKTRPITIDISDDDVAEGEDESDEDEDADEEAEDNKTDGKKQAIGGDGAFSAAAAAVDTAMGDADAEDAEDKQAEAPAAEQQVLEDEDTSEPPSFGDLLRASAPDPIDVDTSAARSARSRKQHPQATSRNASNALRRAAGSPTGAASSPSAGLQRGARSSTAAAVAASAAAPYAPPTTASLGTVLAQALRTNDAALLESCLAVHDLAGIRATVERLPSGLAAGLLGRVAERMHARPGRAGHLMVWVQWCLVAHGGYLAGQPEVMGRLRGLSRVVEERARGLDPLLRLKGRLDLLAAQVEVRKRVMEGQREGGVGRGEEGGEAFVYVEGEGDEGDEVDEGDEGDEDEEQVVGGTGKGGLKGPKAKEIVFDDDEGDDDENVDPMPTTNGLGSEEEDEDEEAGSEEEDLFDTEAEETEDDDGDDVEDEEDDDGDEEGESIGESFIVGDEEEEGEEDDELASPRPAKKSRSGLMGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P972</accession>
    <name>A0A6A6P972_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P972"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="95" mass="11014" checksum="79ED9AE176A76E62" modified="2020-06-17" version="1">MGMQKARSRNGRKMVSWSCARVPGQRVMARLPARGRLLWRSAGGVLAVESFILHPLYYFLLFFLLSDWSLFFVLGLLCTCGAKWLWRHLSFFRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9G8</accession>
    <name>A0A6A6P9G8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_167076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9G8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="18886" checksum="02BCA153D48E5507" modified="2020-06-17" version="1">MGHGPACNIDRKQFLPPATPCRILFPYHKSEISRARTAWPVGHTANKRTRSCHPRSLEYTACGVPRRPKSRLSLAHSPGRSEIPQPPRRPFCAHSLCRSPSTIIGRGIKVPTQADMKIVIYDLNLSPMTYCGSSSSLCAPWAPRGTQSIRCTHPPATGRNLTRLRRRWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H6</accession>
    <name>A0A6A6P9H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ser/Thr protein phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H6"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="336" mass="37334" checksum="D8A6A10332B64818" modified="2020-06-17" version="1">MAATATAAAASPQSIRTRFLIISDTHNATPQSWSDLTCAFRHPLPAADVAIHCGDLTYSGRLEEYAAAIETLASVDAELKLVIAGNHDMSLDAEYYAERGALRHGRRFDPELPSKARDMWLGPEGAARRAGITYLEEGMHRFRLKSGARLNVYASPYQPEFCYWAFPYQRDEDRFNPAPAEPDPSIKNIATNPVPDFPEVDVMMTHGPPLYHLDRTVSLEDVGCAHLLRAAARARPRLHCFGHIHEGWGAERVKWANGTKGLDLVARTDKFQWNQDAVLQNRAAHVNVSSTESLSSLEFGRETLMVNASIMSVRYKPVNAPWLIDLDLPAAGEQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9N8</accession>
    <name>A0A6A6P9N8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAVE subunit 2/Rogdi</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_413472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9N8"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028241">
        <property type="entry name" value="RAVE2/Rogdi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618">
        <property type="entry name" value="LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618:SF1">
        <property type="entry name" value="PROTEIN ROGDI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10259">
        <property type="entry name" value="Rogdi_lz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="35081" checksum="616568FB2477BC02" modified="2020-06-17" version="1">MAAAVWPALPPAQLKSAEDDAQARELEWLLASLQETLQSLKAGLEECAALLAPTEAGSTLAMSSHRSEALKGFLTRVGTRIVKGDIKLRLPSLPPPRHAPAHSPVALTLSTAPTAPTPLPLAQLSAVRSLLDASLDVIDVSAWGGDAGSAPFMAGQLRLLAEHVADARAALKGGAGPDESPADVAGPWWAVATAQDAWVPPLPPNVALNVHVADAALVLEVRTLEPVPPGSYAAARAERGAQHGTGAGGVFGFGIRDRLAYALGTGGSRQPAHDEVGEVFMWKGGEVKVREKVRVESQDPSLIAAMAKLGALEHTVALSRRALDVVMGKEEDEEGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Q6</accession>
    <name>A0A6A6P9Q6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Sodium/potassium exporting P-type ATPase 1</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">BDY21DRAFT_171239</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Q6"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140352">
        <property type="term" value="P:export from cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000016">
        <property type="entry name" value="Calcium-transporting P-type ATPase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 24" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="847"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="880"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="931"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="972"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="1023"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="1053"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="25">
        <location>
            <begin position="92"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00073741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAF2460680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1115" mass="118265" checksum="38A36E268ABC302F" modified="2020-06-17" version="1">MGIEEAQLNVEESTEPPIPSSPDASARRDHLGLAPSVKEASAAAAAGAAAFSADHSAAAAAGGSSRNSTLEGTAVGSSSATVHREWEEEYKHAHTLTVEETTDLLGTDVQNGLSSAEATSRFQRDGPNKVKGAKGLSVWEILLRQVSNSLTLVLVITMALSYGINDYIEGGVITAVILLNIVVGFVQDYHAEKTIESLYALAAPVSKVIRDGRIDSIKAETLVVGDVVLLAVGDIIPADLRLFDGINASAEEALLTGESVPVSKTPQLTFTDRDMPIGDRTNMAWCGSTVAQGRATGIVVSTGMRTEMGKIAELLRNSNDKIDASNKVVYAWKLFVSNLKKILGLVGTPLQVKLSKFALLLFALAILLALIVFSANKWDIEGEVLIYGICVGVAVIPESLIAVLTITVAVGTKAMAKGNVIVRKLQALEAVGGVTNICSDKTGTLTQGKMVARKVWIPGSGVLTVNDTQNPFDPGSGYVDTDDWTGSEIVREDARMQTFLNAIALCNLATVFDENALPQPPGGGGNAEHGGASSPTSTAWTAHGEPTEIALQVLAMRFGRGKAELLGNGDRELAAEFGFDSSIKRMTVVYRQRASGSTTTTEAYMKGAAEVILPLLTVSPAEAERIRARVERMAGEGLRVLCVAHRVLARDGAAPDEKMSDRDAVERHLDFVGLVGLYDPPRVETADAVRKCQVAGITVHMLTGDHVGTATAIAREVGILDGAGAKAPVAARSAATAVMPAEQFDKLSDEEIDRVDPLPLVIARCSPMTKVRMVEAMHRRNAYCVMTGDGVNDSPALKRAHVGIAMGMNGSDVAKEAADMVLTDDNFASIVKAVEEGRRLFDNIQKFLMHLLISNISQVILLLIGLAFKDADGDSIFPLAPLEILWVNLITSSFLAIGLGLEEAQPDIMLRPPHDPRVGVFTRELITDKMLYGSFMGGLCLAAFASVAYGAGGGDLGEGCNEGFGASCETVFRARATAYATLTYLLLVTAWEVKHFARSIFALDPAFASGPWAVFPTLWRNRFLFWAVVAGAAVAFPVVYLPVVNREVFKHAAIGWEWGVVAGCVVVYTAGVEAWKAVKRRCGIGSGRVGVVSVEEAVVRAGLVEEGGGAGGWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9U7</accession>
    <name>A0A6A6P9U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_171912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9U7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16921" checksum="597BF7FF865023EF" modified="2020-06-17" version="1">MRDAGLAATPVFPAKAPRGPRVPLLPAHPAESLDRSHGGCTGVGINRVFSALDRMFDLRERWTLRHQQRGNFTSLRGRDSFCTGGMPPVLSPHMRCTFRCQCSPLGAPIARVSRGLPVAHFHCMQKSCTSPRTCPSSRALACRMLAPHTSPTLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9V7</accession>
    <name>A0A6A6P9V7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Velvet factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_171184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9V7"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="46"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="377" mass="41810" checksum="3A033AC9A5ECEBBC" modified="2020-06-17" version="1">MNRGFDDHSGFMYPQYAHAQYAAARPYTFEHLGQPPPSLGFPTEPDRWVTAIELEMRQQPAEALVTVPGKEKARKPVDPPPIIQLKVDKNGDPGQHFLQSPYLFTCATLCNEKGEPIQREQKEQLVGSLVSSLHRLKDVNNADGGFFVFGDISVRVTGTHRLMFSLFSYSKQTESVHFLKSIHSEPFKVVTQKHFKGLEESTYLSRAFSDQGVRLRLRKEPRAMMAGGTHKRGYQYALAPEADADSRPPPTNSGEDGYGNQNNQTHGDYVPSKRFKADNPGPIPVHPPDVYRQPWSYGSEYQTQAVDRSMPYLGTTPSSSSVTSPMSQGLPLASLTSSSQPLPLNSSSQQLTQMGFSSGPPVSSDPNQDNNYLAPFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9W9</accession>
    <name>A0A6A6P9W9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9W9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="17375" checksum="48788F2B4DEAB30A" modified="2020-06-17" version="1">MGLHLGVEGVPKLLPVTRPRLFERDTQFLFHVTSCPGRHIRPHSHPHSHTLSVKRAYTTKRISILGECRHTCAVGSPVPLIIHKLGPCEDDHSPTVPSPPFPSPMLPRADALPSLSLVHVEYHPGVAVRPHAGIDNEGLERERRRPCDVSPHALPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA24</accession>
    <name>A0A6A6PA24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein HIR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_314478</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA24"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000290">
        <property type="entry name" value="Protein HIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001557">
        <property type="entry name" value="Protein HIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019015">
        <property type="entry name" value="HIRA_B_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09453">
        <property type="entry name" value="HIRA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 11 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="15">
        <location>
            <begin position="29"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="66"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="169"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="14">
        <location>
            <begin position="738"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="434"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="563"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="643"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="863"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="863"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2460729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1063" mass="114793" checksum="2B615E6F790D8955" modified="2020-06-17" version="1">MHIVKPSWLTHGGELRDFEVYSCHVSPDGSRLVTAAGDGYVRIWSTEAIMHCGDAGYSNPKQLAAISNHSGTIHTVRFSGNGRYLASGADDKIVCVYVLDPNPPTHASTFGTNEPPPVENWRVVRRLIGHDNDVQDLGWSYDSSILVSVGLDSKIVVWSGATFEKLKTISYHQSHVKGITFDPANKYFATASDDRSIKIFRFNSPAPQATAHDQVHNFTLEKSITAPFESSPLTTYFRRCSWSPDGNHIAAANAVNGPVSSVAIINRGTWDGDINLIGHEGPVEVCAFSPRMFYKSPVGHAELDANGHSTQVSVTVVACAGQDKTLSIWNTSFARPFVVHHDIAAKAITDLAWSPDGETLFITSLDGGVTAAVFEEGELGYPAPLQENEKNLSKYGAGRKAGVIEGTDALLLEERSKAGELKGVQGRMGELMGDAGVSKPAVPTNGSIDGPRTNGAVDAQAGTNGTTQAPPVPPPAERKVNELKSRVTWVNGKKRVQPTLLSSSGPSASESSLPQTQLISATKQGVKSDSPHAVLDLSKPYDGFPKGGLASLLIGNKRKFAEVEGDEEKRNERRMGSQAQSGAPPILLNTPDGLVPPSAAIQPQDYEVPEPLRPAVSNPALSVSQVRMAIPLIRSVIVRTVDGSEPPPQASNGADVTPAQRTEGANEEVVMLEARNATGPSRTGRHQDKDPTRITCTKRGQSLWQDYLPKPVLLLTGNPKFWAASCDDGSLFVWTPAGRRLVNAMIVDATPVILDCRGWFLLCVTAVGMCHVWNMKTLSAPHPPVSLAPALDVALHVQGMHLTHAPGVVFARLNSAGRIIVAMTNGDGYSYNPQLFVWQRLCEPWWAVGSQYWNTTDAAVGNLQPSSGAQPQSSTSAAKTSPEEDNDEVSPENVSAGIIPLLERNTTNHTLVRGRAYFLQRLIKALLSAEGFEGFESCVSVAHLENRVAAALSLGAREEFKVYLLMYAKRLGAEGLKAKVEELLRSLVGDVFEGEGGDDADEEAKEMEQTLCGWKKEELLKEVVLVLGKHRDLQRTIVPYARLLDIFDKRAAVDEPQQMITDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAG3</accession>
    <name>A0A6A6PAG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAG3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025643697" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9967" checksum="634636B39D9A9588" modified="2020-06-17" version="1">MVWFLRALLLPSMPDALWHFGPRSLPAVVVLSSGRPKGEAGSGVKGRLATYHGGRKMPSRLEWVWFFFPLKLKLKLRLKLDPSTPAPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAL6</accession>
    <name>A0A6A6PAL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_418884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAL6"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="17480" checksum="7302594525C107E0" modified="2020-06-17" version="1">MRLDQIQTKAVHTAVDEFLKSIEPDAVCAIASPFYDRTPRRVSGIENGSFNHCYFAVFDAEDDGNADRRVVQIPTRPRLGCLDKKARSEIATIKLYRYSLSSNNPIDSPFIVLEYIDGSLLLVKDVRNKEYNHYIFRQVARLLLQLHELTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAM0</accession>
    <name>A0A6A6PAM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_383704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAM0"/>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="276" mass="28777" checksum="CA798D477BFE9E46" modified="2020-06-17" version="1">MAMMQAANRLQKALKKGGPTFGAWQMLPGSSHSRTLARSGVEWICIDTEHGNVDDGQMHEAVGTISSCNISPVVRIAANEPWMVKRALDAGAHGVVVPLLYTADDARRLVSSAKFPPQGTRGFGSPFPMASFGNPGPTASEYLQEANDALVTVVQIETKEALENVDEIAGVPGVDVLLVGPFDLGNNIGFPILDGAMAPELHDAIARVLGAAARAGKRTGIYCTSGQQGRTYAEMGFNMVSVAADMIAIPAYFASALAAAKGESGGGAKMTGPYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAR1</accession>
    <name>A0A6A6PAR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAR1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="5880" checksum="2A3177F7300901F4" modified="2020-06-17" version="1">MDAQTPAQSSTPAPLPDCPRAAVSQTSATLPSRGSGCVPPNLPASPTARLPIVPSFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBL9</accession>
    <name>A0A6A6PBL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_279452</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBL9"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000033">
        <property type="entry name" value="Formin binding protein (FNB3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000034">
        <property type="entry name" value="Formin binding protein (FNB3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000013">
        <property type="entry name" value="pre-mRNA-processing protein 40A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25432">
        <property type="entry name" value="FF_PRPF40A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="9">
        <location>
            <begin position="156"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="9">
        <location>
            <begin position="225"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="9">
        <location>
            <begin position="372"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="509"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="593"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="593"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="706"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="728"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="794" mass="94009" checksum="C59017C8C760B7ED" modified="2020-06-17" version="1">MSTPAPAVGGVWKEASTDDGRVYFYNTQTKATQWHKPPEMLSAVDRALANLPWKEYSSNGRKYWYNTETKETTWDMPSAVKEAMEAQPPAQQLAPQHQLPPRPAQAPPQFVAGGFPSFPPQPGHQKARNEHMHPPHTQQEFTRGISAIAQQDQQHYASPDEAEAAFFKVLKRCGVNIGSTWNDVMRTVAKEPQYRAIKEPKDRKAAFEKYIADLKTHETERESERLAKLRADFRVMLKSHPEIVRYTRWKTARPFIDGEMIFKSTKSEEERRRLFEEYIVELKKEHEQQQGKKRLEAMNALTNLFKKELDPETPTRWHDGLARIRSTEEFQNNEIFKALSKFDILNTFDGYIKALERKFNEDRQKQKIMEAREERKNRDNFRALLRELDTAGRIKANTTWKQIVSLIEDDPRYIAMLGQSGSRFHGGDRRHDLPKSGPMDLFRDVVEEHEEKLRETRADILEVLREKRLDVTPKTKLDEVLGVVRADPRTAHYDHDSVSLIFEREVERQRMRHDDDRKTERHADRRADRHSDHHERRAVDNLRSVIKHLDPPVAAGDTWDKVRPRIENTDEYRALGSEELCRMAFEKHIRRLKDKEEEHERDRSRRDRERDRERDRERDRERDRERDRERDRDRERDRERAARDRNHDYRDTRNGHSSRSRRRRTHTRSPEPDAYEADRRKAQADRERQYRKGSTGLSPPPLSSRSRRDRERPVADRYEPARTPTSSHYDRERREREAERERSYVSRADPRDRNVGELDYGEGSARAGSARRRRNSSIDSRDARASKVCYRLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBZ4</accession>
    <name>A0A6A6PBZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CTP:phosphocholine cytidylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phosphorylcholine transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_88260</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="9"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBZ4"/>
    <dbReference type="OrthoDB" id="17102at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004105">
        <property type="term" value="F:choline-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000147">
        <property type="entry name" value="Cholinephosphate cytidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="163"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="359"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="437"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00076205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00080967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2461501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="492" mass="54236" checksum="1D07898997B63CCD" modified="2020-06-17" version="1">MPPKRKRANTAASRAAALENPPQPSSRDASEEDAEDLVLQEVTRHKQTEATAASNTNNPPSKRTRASIWAENNAADVDDQNIETSEADDAQQGAETRLSKPGRRSTRSSMSKAGEAKVDDPLDQGEGGERGAMRMEDPPKAGLVDPKGYRTNPPPTDRPVRVYADGVFDLFHLGHMRQLQQAKLAFPNTYLIVGVTGDKETHRRKGLTVLSAKERAESVRHCKWVDEVVEDCPWIIADAPEFMEKYKIDYVAHDDIPYGADEGDDIYSPIKKQGKFLVTQRTEGVSTTGIITKIVRDYEKYISRQLKRGTPRQELNVSWLKKNELEIKRTMGELRDNIRTNWTTTGQEIGRDLRQFLQSSRPASPARTPGREVSDPMTSPKERVATAGSPSTPSAVAHLSHLDIPNRASNSNGSGSSDFAAGYSLGLIGSVRSWMSKSKRTLNDSRPESPGSETDSTSGEKSAEADASRGRQGKHVQEEVDAQVVDEMDLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC10</accession>
    <name>A0A6A6PC10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC10"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="18815" checksum="DD2C136C63E91937" modified="2020-06-17" version="1">MEGEAGAVPDVSSRAPGSPPRASGEEGEGDCERVRWRRSPGERGAWCCGSRGSIGARQGTGVRCVPSPGRPAWPGRCGAGERVRAPTPSAVGLRCTDGQRRAVLLGRRQRFFLFPGRVLSGGAGSRQRPAMPAPAVNGRNGDNAKFSNQRKRTDGEDSAPSRRRVADRAERGRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC51</accession>
    <name>A0A6A6PC51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WD40-repeat-containing domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC51"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13443" checksum="7A7EEB7BFBF4625D" modified="2020-06-17" version="1">MRSAYATGSASTWEVWAGGTDGRVRVWREPWAKEGCVEPEDEPEDRWPVHGSPVCGLAQHPYYQDVVATCSGEKDQITWSEDKEELELRSCPDSSIKIWTLPDADPQSKGFSANEALVGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC83</accession>
    <name>A0A6A6PC83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_331891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC83"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="8754" checksum="719208904505D04C" modified="2020-06-17" version="1">MGAAMVVVVLAKVCLGRKGGARRKRTSGLLRVRVVLEAQLSAAVGLDSSRNSNYSSSCGPHRRPWVLTNASYKRRPCRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCK6</accession>
    <name>A0A6A6PCK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_398566</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCK6"/>
    <dbReference type="OrthoDB" id="539158at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000692">
        <property type="entry name" value="Serine/threonine protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="61447" checksum="54DCBEA0271DA94B" modified="2020-06-17" version="1">MTVPPSSQVAPLPNNLPFRVVSRTIGQGAYASIRKAIPLHATKPVIAIKFVNKEHAFGTGRLSAKQLLTEISLHRHLGKHTNVIQFLAHGEDPGWTWIAMELAEGGDLFDKIEADQGVGEDVAHFYFSQLVNAVGYMHSKGVAHRDLKPENMLLSGEGDLKLADFGLAALFRNDQGQSRLCKGVCGSPPYMAPEVVGGKRPPGATQGGVPRKDVLERGYAPDAADIWSCGVVLFVLLAGNTPWDEPTPRSYEFAAYVSAKGRPGGAGYADEELWWRLPAGALSLLRGMLKLDPAARFGLDEVRTHPWFTRENPHLSPAGTAANPVGLATQMLESLRIDFSADPTTMPLSQQEQRRRVAAAADAMDIDDGAARFASTQPETPLQDMAFDWERPARADALHGISASQPASGAGTGAGPRGGASTSRAPLLLDGLANDPSLSQFMATPSVPESLTQAARRFRDIVPAHSLARFLSGAAPALLLATLAAALHRLGVPVPPETAAAARAEALRAQGEAWIRVKTVDGRQQGLNGNVVVETVGDGVWEVRFLKAKGDPLEWRRFFKKVAVLCKDVVLLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCW9</accession>
    <name>A0A6A6PCW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_92156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCW9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="136" mass="15278" checksum="727CED45EFE902CE" modified="2020-06-17" version="1">MSCRTTIFVRPYSSRFARLSFPPRSTPPFRFLHTHGWEKPQGPVRGRRDGQGRRTYVVTVSFFTRLLYVPAHTDVLSRQRLFPCRKTARDACGTGSTRWCPLPGYPSMAGRGQVPDPSPGPRPLWCGKMRAVGGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD58</accession>
    <name>A0A6A6PD58_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_398692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD58"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="241" mass="25670" checksum="6095DFD93A094B1F" modified="2020-06-17" version="1" fragment="single">DAGIYIADAADGQKGRGSQGRPARSCPRSHGCANCRAKARSAGRWDLAAAALAAPSARRCAWHGTAAGLRTRALPPAPAVRSAGSRTGSRAREGDERTALWRARGRVRGGDWRRNWRCAEGPRRRRPPRLGHPCGGAPPRPPSANTPRAPGGGGGGGAGRRRALLGRAVESARPLRAAADGLHAACPPTWHQLPPRRPYLLRCRPQLKEGKELRISGASQNPPPADEDARRQARYQRPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDA3</accession>
    <name>A0A6A6PDA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative iron/copper transporter Atx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_333115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATX1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDA3"/>
    <dbReference type="OrthoDB" id="689350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000008">
        <property type="entry name" value="Copper transport protein ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051881">
        <property type="entry name" value="Copper_transport_ATOX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365:SF1">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="8659" checksum="CF05C8276517D054" modified="2020-06-17" version="1">MAEHNYKFNVSMSCGGCSGAVERVLKKLDGVKSYNVSLDSQTAEIVAADSLDYDTVLATIKKTGKKVNTGEADGQPMKVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDD8</accession>
    <name>A0A6A6PDD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SacI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_389282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDD8"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034753">
        <property type="entry name" value="hSac2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022158">
        <property type="entry name" value="Inositol_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF7">
        <property type="entry name" value="SACI DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G15890)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12456">
        <property type="entry name" value="hSac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51791">
        <property type="entry name" value="HSAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025515756" evidence="2">
        <location>
            <begin position="17"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="3">
        <location>
            <begin position="267"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="HSac2" evidence="4">
        <location>
            <begin position="716"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="955" mass="105781" checksum="B405C1210FC27D7A" modified="2020-06-17" version="1">MPGLVRRLLLFAAVDGLVLQPAPPRNHPPTTQQAIKIDYQTNGFSPLFKDRRDEETAPASLETYGLLGMLKVASSSFLISISRREQVAQIRGKPVYVVTDVALIPLSSQAEADKAIVLAREAQKRHGEPEKDEESSGSDTDTIDESSTDSLESDDGHECATSPGAAADEGGSAPARRTSIAEDVIGRKGLYGRFAAKWFSRTGWSAEGRKMQGMSSQERSAIDGAVEANVEDHSEVDIAADDKTKTGDDVPPEQVTISLLPRILRTTKIYFGSRSLYFSYDYDLSRNISKQAQLSNLPLFKQFDELYFWNKHIMEPFIKAGQHSFVLPVIQGFVGQRAFYLDAEAKDEEQQWAEGLQTNEGSITLEELGSKLGDPIKPEDLGPSKRCFTLTLISRRSTARAGLRYLRRGVDETGASANTVETEQILSNCDWEASTASPIFSFVQVRGSIPLFFSQSPYSLKPLPIFWGSPETNAAAFRRHFANLATRYGSIVAVSLVDRRGTEAKIGEAYEQAANSLNESEDGIDGKGSQLAFKWFDFHNECRGMRFENVSRLIDALDPILEQHQWITMELDSGHPSKVQTGVVRTNCMDCLDRTNVVQSALGRWALTSQLATQNLTINLHSDPLTAWFNTLWADNGDAISRQYAGTAALKGDYTRTRRRHLVGALADFGLTLSRYYTNIVNDYFAQAVIDYLLGRASVDVFADFEADLIAADCAVDLRRVRQAAISTCAQMTIEGPDEDLVAGWTLSCPAETGATKSARYEESVLLLTDRAVYLCRFDWGTEKVREFERVGLGTVTSLRRGVYITNTLAPKHMNEKRNVGFMILYKAPEKGEGLVRVNTRSLASEKETGEEPTSPGIPKTPEDAAQRHELSLSFKALPPSSSYMSMEGQEGEPLSEREMIDAITDEIVRVARNYQESSDKPKVEEKDIISLEEAKRSTGLLEQIGYSLKKLVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDI4</accession>
    <name>A0A6A6PDI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF427 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDI4"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310:SF5">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="98" mass="11019" checksum="A2B98CA696A60B5C" modified="2020-06-17" version="1">MPHATAKVDGVTVAETDSYEVVEGNIYFPPSSVNKNYFASTDKHTTCPWKGRASYYTIDVNGTSYKDSAWYYPEPKSKASHIKNYVAFYTSKIDVTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDM2</accession>
    <name>A0A6A6PDM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_383132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDM2"/>
    <dbReference type="OrthoDB" id="5311681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="63532" checksum="B417FDC10DCFE823" modified="2020-06-17" version="1">MDRHGSGLPYQSVHTSPVAMDAVALFVRFPLSVSVRIISFVDDVADLARLVRTSRFFYYLVTPLLYERVTLRSYDQIRYINGKPEGYGSGSPFSVGLNGLVTGDKGQYVKSLRLCGEWREHDLEDFTRGRVPDSSMMLNTVVRVAIGNMPRLRSFSWELNTKPMRAVYQGLASCSGLTSLIIKFPSTRVPRPVTVVPPMPNLKTFKAIELDPLCYPDDISVLLLNSKKLLDLTVHFSPRMREQGEPSINVHAIFGKCVLAGYALPVQRVAVANMYAKHQAELEHVINMETLREVVTINCGQSATDPSTVFLDEDWLSHKPHHLAKNLKVLRIDQPTAQLARLMNEFSGLECLYVVNERYVPQSKSGSSAGTTPGGSNSDSQVATSKARAGTPLSPTSSSMQEQLVSVASDVIAAITKSHGESIRHLLLSDQWTLDHNVIMRIVHACPHLEQLGVSIYANKELEALRYALMGLPKLVALRILFPRDENLESHLASVGDQTHAFVLSAEVVRDHCPRLKWVGLGSRVFKVGPLVPNSEKKRAQNGEPRPMRIITPASADDVKDVEIWSMDRFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE65</accession>
    <name>A0A6A6PE65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE65"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="216" mass="25231" checksum="872D91380338B690" modified="2020-06-17" version="1">MLFQRKLASPFEYSKGGRSLLLEAAMLGHLEIVEFLLQQGADPDNCLLKPSSLQKLSLVFWRLSAAPPKVSLTLSCIQHSLKDLPLTAAEILLIEDIDLRYCSDHLNIFRFTGDTFGTHDLLYAFRKFMRARSLSLEWKITDEFLRSCRRDNWLIQYYFDTILFHFLKANRPEIDITEKGLSMAVERFKRFKPETVKSLLNWNVRELQNTHEVLEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED7</accession>
    <name>A0A6A6PED7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_277352</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED7"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="341" mass="36896" checksum="0F11883B9414FBA0" modified="2020-06-17" version="1">MRFKAQIHNVSTFSKFAASLASLGPVAWVRLSDSDVRFTVIPEQGTQVWSYDTVFETHTIQSAAGNIINLEIPIAQLHRALKSALSATSASIRLTKKDGVPILCLTITSSSLSTSSFNRDADDDENTGGGSGPHTQSFDMATGGQHRARETIVTQDIPIRVLSPESVEGIHEPRCREPDVHIYLPDLLQVKSISDRFTRMAAAVRGGSATSAASSGPRLEMAANMHGCLRLSIRTDSMNVSSVWIGLSHPQLDPELLEGGLAEHPSTRMKQLGSADGTSEEGWSTVRIDGKDWGKVMSVGRLGGRVIACFCDDHALILYVFLSGEDEQESVLTYYISSYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED8</accession>
    <name>A0A6A6PED8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_277829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED8"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015501">
        <property type="term" value="F:glutamate:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015175">
        <property type="term" value="F:neutral L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050746">
        <property type="entry name" value="DAACS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11958:SF63">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11958">
        <property type="entry name" value="SODIUM/DICARBOXYLATE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0769">Symport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="472" mass="50922" checksum="06E447C25E296716" modified="2020-06-17" version="1">MSEKDLKNVESQQRPAVSVGYVEEETRPKRPWWYSVTEAGSAIQIIIAAALGIAIGLAVTTSVDEVPDAAVAIVGIPGVLWLRALKAVVLPLIVCAMILAIQRLREMSRGGGVLARWTIGYYVLTTLCAVIISIIMVSQVWDGLMTEAGADSLAVAEEDEEEFSEREDVEVHDVVVQMFESLIPANIVDALASDSLLAVLISSIVVGYLIRGPDSPILRATKEVERIITVIITFLIKIAPIGVFFLIVSNLFRLRIEDIGRNLGVLIGGTLSTMAIHLFIVVPLIYTIVLRKNPYVYWFRNAPAWLTAWGSASSAATLPVTLKCARARGIPNLVAKFACPLGALINMDGTAIYFPVVVVFMAVTQGIWLNAADYVIICLLATLASIGTTPIPSSSLVLTVMIAGSVNVPVTGMYAVVVTIDWFLDRFRTALNVSGDLYAAAVVAKITGIQDPDNMDGEVEEVEVHANNSDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEL2</accession>
    <name>A0A6A6PEL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_10530</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEL2"/>
    <dbReference type="OrthoDB" id="5632at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032954">
        <property type="term" value="P:regulation of cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000038">
        <property type="entry name" value="Tyrosine-protein phosphatase CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="15">
        <location>
            <begin position="260"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="16">
        <location>
            <begin position="326"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="43"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="416"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="659"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="520"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2462250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="699" mass="76611" checksum="3C52D8368398C464" modified="2020-06-17" version="1">MPSAHSRAQSAAEATTLSQPPAQVRGQVIEYIQDRLYLAAYDRPPSAKSPFPYPSRQSPKKRSSRAPQGPTPSSGPKVHPPVYFSVDDTLLYNAFHADFGPLHIGHLYRFAVQLHEVLGDPANEGRGVVFWSYFNPRSRANAACILACYMIMIQSWPPHLVLAPIAQMDPPCMPFRDAGYSQADYVLNIQDVVYGVWKAKEEGICSLRDFSLEEYEAFERVDMGDFNWITADFLAFASPQHEPTAVIPPHSPHYASLPKTIAEVARNEQLPLPFKNVLTHFVDRNVGLVVRLNSALYSPSYFTSLGIEHLDMIFDDGTCPPLELVRRFINLAHDMIYNKQRRIAVHCKAGLGRTGCLIGAYLIYRHGFTANEIIAFMRFMRPGMVVGPQQHWLHLNQGAFREWYWEDRMAAATKASISTALPSTPTRPETSRSKSQRLASATSATHTPPGSAKRSALGDITSHEQRSASGTYHPVADDYKPRNSSSSYVHVADDNLPAPTPGQPRKTSKAYGANHSPLRSSTTAGASATAVDENERPEAEIVSFETRRARQAAAGDESDEEFQLRMLARHHHTRNGRGSRSPVSSHHHGLQQASPTKGAAAAEAANKRRAVSCTTTTLTTSVARWSVEPSEDSDVENQFVGVIPATPSVTEAKKISGKGDLSVGKVRGSPTRRSGENGRVATGVRKTSGRVGSAGNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEM6</accession>
    <name>A0A6A6PEM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor Pcc1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEM6"/>
    <dbReference type="OrthoDB" id="10025739at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283">
        <property type="entry name" value="EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283:SF5">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT LAGE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="114" mass="11731" checksum="9F5A744D2C97B130" modified="2020-06-17" version="1" fragment="single">PPASTLTIPFPTARLASTAERALAVDAELSPLVRRSFSLGGIHGGGDDETVLKVEYAATTNRMLRVAVNGFFESLGVVLGVMEELDVDVVGLPGKESVAGAQGVAPIAEGERAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEZ9</accession>
    <name>A0A6A6PEZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Quinon protein alcohol dehydrogenase-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_418211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEZ9"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="150"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="334"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="376"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="457" mass="46712" checksum="DED6F0980D3C1D60" modified="2020-06-17" version="1">MAGSSDADKYFQTTASLEASERKSAKAKNTHGNPVKLPSKLLAVLADNALPPHDASNTIFIAEARGAVRRLAIDTGETTALFTGPTAPVPCIALAPIALATHPSSSRAPRTLFAGCWDKVIYAWPCPPPPPTPSPSARPSAPAVKPALTLAGHTDFVKALAVTPPLGAPPRRLLLSGGADGALLAWDAGSGARPCAAVRGAHARGVLALAVAPPAGWADGGASAGAGDAARALDEVEVLSGSSGGEIKRWKLSVSGAGGAGGAGGGEEADGVRLEECGEPLGVHATSVHALRVDADGELWTASADRTAKNLVAEQEGEGGAGAGGRRAWREAMALAHPDFVRDVCVDDAGGWVVTGCRDEAVRVWDKGTGSLHHAFAGHYEEVTGVALLPGTRTVASVSIDGTVRRWSLAPAELERARAEAAMAREPKGKEADGAPTSSLLTEEEEKELAELMDEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL53</accession>
    <name>A0A6A6NL53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_406831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL53"/>
    <dbReference type="OrthoDB" id="206335at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000019">
        <property type="entry name" value="RNA exonuclease NEF-sp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="282"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="677" mass="75085" checksum="8C0B8621DDFC3B3B" modified="2020-06-17" version="1">MEAHQPRDDATKPEPTAENDGEWEVVAERGKRKKHPKHTGPPSFSFSPSCRLQTSVKLNDLQLLILYLFEADKAPTWISVANRPAVRRIVTVMVPGLERGMFDGSVPLRDSFAIKNESEASDTTEKPPTGGTSPDEWYPVKLVAGALPQELKPLAEIFPLLWPVQAPGDARYSKLHSPIGGILQAKRTEKAKHWKGPNNINGSKRMPITKCLSSLEDLQEIDYPLHPALFITEEDKVRNSLSRQDRKQTTQYGWADSSVERLEDGEVADKDIEVGSITQGRTVLAIDCEMCQTEESSCELTRVSVTSWDGSVVLDTLVKPSSHITDYLTRYSGITEEMMAPVTTTLADVQRQLKEIVTPTTILVGHSLDSDLKALKFTHPFIVDTALLYPHPVGAPLRQSLKFLAQKHLKREIQQRHGTTGHDSVEDSKAALDLVKLKCENGEDYGTSEAATESIFKRLSRQRKPGNFVVSASNVYRTSACVDWGQPRKGHGACATVSFGCKSDEEVVQGIARALKGDSGIISADNVSAVGGAAPPGGVDFVWARLRELEAYRGWWNRSKTVDNEELRQAVISTSRDDTGDKDQNPPTLAEHVANTVKRIIEIYDALPSCSALIVYSGSGDPRQVSRMQELQKQFREEYRTKKWDELSVQWTDTEEQALKNACIQAKKGIGFLTIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLG0</accession>
    <name>A0A6A6NLG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLG0"/>
    <dbReference type="OrthoDB" id="5431013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="754"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="867" mass="96388" checksum="E9A919172A2C7356" modified="2020-06-17" version="1">MPDVFRADRIRQLATRSTALTTKLYRASAESSVHEPQELIDLARTAKELSGSLKNVRSALDGDKHSLPSRASFDALELVIGQANEVYDGIEFSLNSPSRNDAPGPSDIADGLDLSCGPLSKANCLLKSLEALKWTLSVITHALITAKVINTVQAPLMEKTAEPVATVRADLESIVIEQQLALLRARQAWERFDDALHEYLDSIDDIDFPFPPRSDDRSVSPLSTGSKSPREAHIASLLSFQEESLRNTKVPPSETECVVLVLDVYVSHTDDVLRRWTCLTEIEHRVREHMNRKSSHQDSAADARRRSQQPTVETDDESTLELEESRSRKKSGVISPLMSPVPQRPGPSAESLASRVVPPIEIPKTVPETTAPPPLMPNGQPAQVNMASSPTSSRYSPASNRSYHSVSQSTSSSTQISPRSSISSVTPSVGPPVVHKPASRIQEDEDVYQLDRPWRLCAGDMYWDFVNDVCLGRNTKAHHSVAYSHRRAYTEIMEEWICREALKEAGLEFQRVTKMGMDPRRTRTEGSGCYCIYRALTYEQVKALIDRSVEIIADKRARKASCSLTSRSSRGLPRGFSSPNIPTHPIDIPQAAAPRRESSDHLPQSRQHATPPQPGLSPYSPTHHLQGPQYSPTTSHHPLSRSWSHPTAQSASQQQPQQQQQQHFSPTTAAAPAQGPPPATSAAQAPKTAPPPPSPSSSGVPTPRASSTNRPNSSSRQASFASSAAGTAASHQHQHQRPGYARRGSERGRETPPSSSSDSASGSEWDAWSDEQPRDRDRERERERERDREREREWRHRHRERRPSKRDSRTSSYEGHAYDDREKERDGRRDRDRDRTRDRDRHRRRSSMLTTIGQIAGATALLNGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLU9</accession>
    <name>A0A6A6NLU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_259906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLU9"/>
    <dbReference type="OrthoDB" id="3933142at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19432" checksum="A02F9FC6BA61DAC2" modified="2020-06-17" version="1" fragment="single">VDRGRQNQVPWNIVQPYMESTIALIGKVLRQPAMEAILQHVQDAAKCTENIQRDITTIKNSVGLSTTPPNPANFGGGRPAATTWAQVAAQARDPPPVPPGASATRNQPTVTAYKDRVVTVKLKDHGIARRFRTHPATWIRMQVVTSVHDNAATKSVKIIAAHQLKSGDIQIFTSTTAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM53</accession>
    <name>A0A6A6NM53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM53"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="7452" checksum="F00485433C39B676" modified="2020-06-17" version="1">MFPPKSPHPTGTKPSRKPPTPQFLLFSHHPPKPPGSRYPPLANSRISTHQHHPTPLQTQPPPPQGAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMC6</accession>
    <name>A0A6A6NMC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_152049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMC6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19516" checksum="70898F467556A11F" modified="2020-06-17" version="1">MTWLVRVKLEDGGADAYLCVPGSTLGKAIHQPWPFVYLRVPYADGEAKFRILQSPSVGSAKVWCNSNMPTPSVGGAYHRGERCSTSDEVDMFRGRLGNGHLDRRRGTAENLEAAAAQSDSSRSRARKDRPGCRKGLHSRPGRCAGPRQTVKESQGADGLWFERNGMPARGAQKEMSGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NME7</accession>
    <name>A0A6A6NME7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl transferase/acyl hydrolase/lysophospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_357885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NME7"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="17"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="352" mass="38790" checksum="1B3693C09E68E3B1" modified="2020-06-17" version="1">MDGQRYAMHANGPLVLLALDCGGIRGVCELVILDEIMRQVQSGLGLGDLPKPCDYFHLIGGTGTGGLIALLLGRFQMDTQEALRVYNDLAGAIFSKGNQKWKFQDGAFKATTVEAKVKELVASRDTGEFMMDSATTPEMGKAFVCAMPATNMAHPRRFRTYPARNLASANCSIWEAVRATSVAPTFFKRIAIGEEGRAKEEFVDGSTGCSNPSQEVLEEARNIFGEKRGFCCLVSVGAGHPGTIEQSKPDAFQKMLPRNVVDSLRKITTSCQDAALRLNWRFRRQNNLYFRFNVSQCAGSISLEEWKKTNEIESQTKSYMEETEVTDAIDRLVKLLCAPVESGHFIGDVCQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMS4</accession>
    <name>A0A6A6NMS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_388349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMS4"/>
    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030668">
        <property type="entry name" value="Spermi_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000502">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="44"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="325" mass="36999" checksum="A7F92255056BFE60" modified="2020-06-17" version="1">MKEYTKRVAFDNLQSDRPSFPATIATLLRPTFVMGEITHPTIQDGWFREISDMWPGQAMTLKVKKVLHHEKSQYQDVLIFESTNYGTVLVLDNVIQCTERDEFSYQEMITHLAMNAHPNPKKVLVIGGGDGGVLREVVKHDCVEEAVLCDIDEAVIRLSKQYLPGMAAGFEHPAVKVHVGDGFKFLEDRKHEFDVIITDSSDPEGPAENLFQKPYFELLRDALRDGGVITTQGSENQWLHIELISQLKKACKEVFPVAEYAYTTIPTYPSGQIGFMVCCKDPDRDVKKPLRAWSTEDEERLCKYYSKEIHEAAFVLPIFARKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMT7</accession>
    <name>A0A6A6NMT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMT7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="226" mass="24088" checksum="837E4340A528DD70" modified="2020-06-17" version="1">MPRSAFHPLDSLIKLVPRPVAAPRGASGPRRYPSFPPSVSCTVLRDGHRPVPPGGGSTMQQQQLASSGLSGGGPGRLGEPLSRTMQADGGGGGDWDRSAHISLSVLNGSTCSVLSPSFANGSGESRWSEGWAGNDAVPTRGGNCAYIYAMRSANRNISTERFRWDGGRTRCGSELLRMSAERWWWRAALRMRRFFGPATYAAVLGSGLPLLRGQRDGSWIADSAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNP7</accession>
    <name>A0A6A6NNP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_128787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNP7"/>
    <dbReference type="OrthoDB" id="244495at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="55171" checksum="7CFBB93A809D1B11" modified="2020-06-17" version="1">MPSFYRRATSRDLPPTPPEFVPSGYANGCGAMQYSQASFSGLPGVASRKDGTYDFVDGYGRPSSIPGVTTMVSRHPPGFSNSATSLGQTQRSFYEPMGAPLLPPMRTQESNVVSSSVHLQAQQQAASHAEKPAPKEDKAVGGVSAKLDYDMDVMTEFVSEMTQGMYALLKSPICLADIDIFQNVRPGTTPIPPQYTRWVHQVLSATRLPSATILQSLSYLSIRMTMLSAAGHYRPATEQIYNMLTIALVLGSKFLDDNTFINRSWSEVSHISVAELNRMEMEWLVAMDFNLHRNPSETQGFCSWLAHWKEFEARAIARAVRPMQLSPLDTTVQRQPAIHSSVSPHIYQQQTKPSAFYLPSAKPPSRSQNQWESTTSTYSQPQSQYDPWIMPPRSATEGSPASAPHTGPTTPEYYGNATIWATPQQPQAEGYSRRTMFGFPPVSQPQPQVQQPTYHPATYASHFGHRHWPGHGLGCNCGYCPRQPQYLMAPGHGPQPVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNT0</accession>
    <name>A0A6A6NNT0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_266716</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNT0"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="23775" checksum="5A939C785C61F707" modified="2020-06-17" version="1" fragment="single">QTILVTGANRGIGFSIVQSMATAAPNHTYIVGSRKIAAGEDAVRQLLAIEGLSSVHFEALEIDILSDESVKKAVAEIESRFGGLDTLVNNAGMARIPKPDGSDLRDNFNQTFATNVTATAATTFSFLPLLKKTPAARVINVSSSRGSLTLQTTGKLPPTASIAYTASKSALNVVTLEMQKLAPEVSFWAACPGYCKTAFNGFRGKKDPLDGARVVRELALSESGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP20</accession>
    <name>A0A6A6NP20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_402111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP20"/>
    <dbReference type="OrthoDB" id="3365616at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22952">
        <property type="entry name" value="ART10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF166">
        <property type="entry name" value="ARRESTIN (OR S-ANTIGEN), N-TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02050)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="515" mass="55740" checksum="C42654FD9C480463" modified="2020-06-17" version="1">MIVQIILDRPHSHYTNLDIISGRIQLRTTTNASVSSIVVKLEGESRTRLLPPPKQNGGDRQKYELEVHKLLYKVNTVFPPANVKDSVQQGSSFTLQAGQHEYPFEFKFPFNNSCSATNNLANNINIVGMQLELAKTPAYHVKKTLPPTLSGFPGEAEIKYYVKVTVNRPQFYKENSRAYSVFPFLPIEPPRPSHPDGEVYARQKHQFQLLQPALTPPGGPRKESFFKSLLSKTPSSQSTPGTPSSPTTPDGPQPSTPASPTPAEPPRFSIDARLPNPAILTRGEPLPLRLVATQLSPASSRRGAPLFMQILHVELIGYTDVRAHGIRRRESSSWVLVSLSNMGVALGDASSPAAAAAGAETVVPDRWWADRRVPATVAPSFETCNLARCYDLEVRVGLGFGSRERGKDQLVVLPLRLPVQVLSGIAPPPALLKAMEHAGTLRPAAPPMPPRPSATSASGLPAQSAAGYEDAPPSYEDAIAEELPPVDGPRRDYESPASGQGGMDEGGLGFGREKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP91</accession>
    <name>A0A6A6NP91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP91"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="775"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="650"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="818" mass="87887" checksum="FFC864B3C08F985B" modified="2020-06-17" version="1">MASFINKPLPPLPTLSRRSSSPHRPWTPTHRRGMRHVRHHANHDPDNLLHVAASRSMPALPHPGGTDLQASPLPPLPAAAYQPPPHSLVEPQARRKGFFKRLFGRKKKADRTGTEPEDELDGHEYSSEVSLPESLLQQQWYPEGAKEEGEGGPPSAGKEAKKQRKKLRKKSRKAETEVNPGGNSLAAGIDQQQQQQQQGPELQQPHDHAGAANGGIDNQAPRRMQGPSSLPSPPLSPSTIPTTVILKTVSFTVRSGPAPPSAPASTARSRSSAPEPATRNYPDLDFLFGVPGDAHAEPTYTVSCTAERPPATTNSSRARGGNMRRFMSSMFRTRSAAPAAAAALAAAEAERRFSSPRGGDASSSSSDNWAGDTDPNASTATVNVDPRARVPNPISILRRPDDAARTLRSQSETCVRIRDPSSNRVSRPASSSSSSGGSGPVVEGADEDDDVFAPRAPPPRSASAFVSAAATPGNRTSLNFAFAFPPVPSPLPPPPPRAQPPSRIPRPVWRSPAIASRGANGASQPQLRLRGGASGSPQAEANVRRWLAGAVDDSDEEQAGPSTTSQGSPMPEPATPRRRHDDRRHERRQRRRRRSDRRAESPPALPLRPLDEFRCGEAATSVRAVQGSESPTRVSPVRQSPARPSPARPSPAAAVASPRGPTTPVRSAPRAPARSSPARPSPRTPAGSSPGGGHHRSRRYAPVPTHDAEAGPTTPPPRSPLRAVESAAAAAPAPAAAADDHGQRRRWQWRVPAWMWYVVSGRGRRTAPTADEWREMREMGTMTATPSRRRSRRMQEERERGPQGEEDGVRVVYCCTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPC8</accession>
    <name>A0A6A6NPC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase III RPC4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_375028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPC8"/>
    <dbReference type="OrthoDB" id="5836119at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="576"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="734" mass="77791" checksum="92478316EEE15511" modified="2020-06-17" version="1">MPPRGRPRGSRARGGTTSTRGRVANPNAATEAPAHEDEEPPTAQPQDAAPTETQDATMEDAPGDPVEPAVGAEAQPASTSHPGLTITTSSVQETATAIDAASAAMAHDAADLARSSSIGAASAPMPSSVTLPPSCSETPRRVATLAGVGAGPGAPSGRRALMPQPRGRGRRSAEERQRLQEQEDARRAEQMARLGTVQPTRSAGVAGVVAGGGRGGSGGGVSGARSRGQGRQQQQRGAFMVGPGRGRGRGGFMGDVIASGPFSSGMVSRDTSRFVQRGRPTHSRGGFGSVGASSKPGGPRIKTEAKIKQEDNQDVPMTGVEGNEGVVKREPEDGGYISSDPDEGHEGPLLDVDYINLISDDGTSDEEGGPRSINRRRRPQFDRMSLAPVRLQRHEHKERVVGINTEASSATTAELRRIADETGTANVEEALASAIKKGKAKAKDMEVISDVREFKGAYDEDELDDVTAVRNELAAPETSKPRPESPTSTKKKDDKAIKLSPSSKRRKNQKPVFQTDQDLQEYERRMHDMQVLRDELGSITIAPAETAGEDESILSEQQLPDKKADRVYLFQLPPVLPDLATAQSPPTKREGRNESPTETRAGTSAAQDQNATAAPAKESVTIKQDPGAEPQQGAAEQGPTLAPGYAGKLRIHKSGRATLSWGGASFQMKMGMDTEFLQDVMVVKMDEQPEGDEDGEGAAAKRPPGHIMGETLSFGQVRGKFVVTPDWEEIMGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPE3</accession>
    <name>A0A6A6NPE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_265871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPE3"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF51">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="317" mass="36387" checksum="4F5E2F6B0D2DD64A" modified="2020-06-17" version="1" fragment="single">SPIFGSQHVVFPIVFTDGVQWMLKVPAIGVERHWQDADARGLSSEANTMRLIKRATTIPVPDVLWFEGSLENLLRCPFILMAHVEGISLYEYWFDKKVSEAERTQRNLKVLEQVAEAMLQLDKFSFDQGGSLEFNHEGQFLGIGPMRRLDVDSTNFGLESLHRATESRLDFMVTANYGPYRTPKDFYKNIFTRTWNEYLPDETIFASYNALELLVECIPEPDDGRKAFVLAHPDLSIQNVIISPEDGTVLAIIDWHGTGAVPRSMGNESYPLWLTRDWTASNYQWDHPNCPHTGWSEFEDDPPKTLENLRAEYQRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPL1</accession>
    <name>A0A6A6NPL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3433 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPL1"/>
    <dbReference type="OrthoDB" id="3248909at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544:SF3">
        <property type="entry name" value="SPRAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="69693" checksum="27017A43EA156C2B" modified="2020-06-17" version="1">MGRIVAVEESLGFDVSNFDGNPYEARNILGATAAAQAGQKHGANKSYYFPPDPEKPSWRPMSMEWWYILTLTMIALGLGGYQEYLCQYSIQQKAKGSGLIEFHSVAEDVSVADYFLWKYAPTMILVTYGVMWQISDFEVKRLEPYYQLSQPKGATAAESLNIDYLTFFSYLIPFKALRFKHWAVALSSTATLFAGSLTPVLQSASIITFPPKREWEQDPNGKKFLLVDPAWSRATSAALYCVGICGIMLMWQLRRKSGLLSDPKGIAGIAAMATRSHILQDFQGLDTKSHNAIHQQLKHRRYILHKSSLWQGEYIRNTAAARGADDVAGNKKLRNPHPRMLTLQAGVPYIVSLLIFAGLLPVFIFNERANKVTDAAPWLLVLLATGLKLLWSTLECDVRMVEPFYILSERQAPAKTLTMDYTGTMPGWLPIKAAIGRNFLVALVGLGAILTEVMTVCVSSFGVDGRKFLRFDFNGADDGDGNRGGGQKSSDETFKSFWISFILVQLILLYLAVVAGSVYARRRHRFYPRQPGTIASVLAYIHQSRMLMTFVGCERLTSSEMTKFLEKGGKRYALGWFDGRDGAYHCGIDEEPIDRRYEFGVDPRSERIKVVGTWEHFETAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPZ0</accession>
    <name>A0A6A6NPZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPZ0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="14223" checksum="6854CC9C8126B431" modified="2020-06-17" version="1">MRSLWVVSSADMRLVSFQRSRPCYYISQIRAVSTLSTSARYALVCVIRVERQSRPPTPGNFVAEPWFAVRAGGLLPSARWTRTSRQSVPQASHMPPEPGPRASETVGQLDKLRASDGVRTHNLGRGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ91</accession>
    <name>A0A6A6NQ91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_366611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ91"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="122"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="53727" checksum="D9D38F522B20E046" modified="2020-06-17" version="1">MARLGDILRYGFWSLSALGGLYVLFVASLIHPDVQRFALYAHKISAFWQNLDRPEAFGFARNQVTPFNITTVDGETLYAWHILPLDLYAQNQEDLTISSAAPVDYLESKPFKLLRDDPEARLVINFHGNAGHIAQGWRPDTYRALSSLRPSVPSSACSPSSSSPHTHVLAFDYRGFGRSSGSPSEPGLVADGVAAARWAIDVARVEPRRIVLLGQSLGTAVATGVAEAFALGEVEGAGKAAEGDGHGDGAAVLEADEEDAQARLGGAIPPAGAAAAQNAWRSRDDDHSSSGSEAEPPPTFFASLILVSPFTSLPELLHDYRIFGAVPVLNPLKYTHPRVLPFLQRCVRERWETGERLARAVARAAGAPAGQDPDGGDPPAAPRGSAPRFNLHVIHAATDPDIGFRHGEAVYSAAVRAAAAAREPERRARDRVVSAGRHVVWRAEKGPSREEWWGGGDEEEGEGDSGRLGRLGLSVVGFGGHNRVVTYAPVGVAVLRGFEVGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ94</accession>
    <name>A0A6A6NQ94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_115323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ94"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="18479" checksum="2955B5F92A3030FC" modified="2020-06-17" version="1">MSPDSGVVVVVVASRQYLYIPASRDTAGEGSAPDKASESAAQLPYEARRLKREGREGPCHGKRDWGRAPEVGSIVARSVADCQLIAGDAARAQSFPNLAGAGVAVTGSGRRWLASAAKPHARPLNLTRQGSGTRPCSPQNRRTLKPLDPWNRNMNWRAARAVAPDDGELSSPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQE3</accession>
    <name>A0A6A6NQE3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQE3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="63" mass="6283" checksum="D8748BF6D342CF33" modified="2020-06-17" version="1">MGGGVLGSDQRGASNGCGGCSTGSVVIGISVASEGICLRVGVMGPWISRLGWEDLHDLGLSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQP2</accession>
    <name>A0A6A6NQP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_110983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQP2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17854" checksum="5474DC53440C6550" modified="2020-06-17" version="1">MLVSAISRPSQGLLLLFFETSTRSSHLSRSRRTSARSCSGPSRVPPRQKILRYLADNRSVAARLPKTVATPAFLHSRIGRSVGCEQSHLSRVGSWRGRSRRPARTDPRAGQADRVPVARQSRRADAVEGGLSGRRQLQRQRQRSRSRTRRGEGEHWHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQS5</accession>
    <name>A0A6A6NQS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_355058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQS5"/>
    <dbReference type="OrthoDB" id="5430620at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018909">
        <property type="entry name" value="Eng1_septum"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10645">
        <property type="entry name" value="Carb_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025537578" evidence="1">
        <location>
            <begin position="18"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Endo-1,3(4)-beta-glucanase 1 carbohydrate binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Endo-1,3(4)-beta-glucanase 1 carbohydrate binding" evidence="2">
        <location>
            <begin position="83"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19589" checksum="54EBE858B90FDD8A" modified="2020-06-17" version="1">MKILLSVLFGAATAALAQDLQWCGSARYDPAQYTCFDGDFLCPIENGEPTLRCGDACYKQDAYGCSNGVLVPNDPSDPDLLLSCGDAKYSPSQYVCFDNGFLCPVINGNPTLRCGDACYNYDQYKCEDGQLVQIQAQEPQCHAVYDFCVRDGMVYPCCEGLLCIATRCRDPADFDRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR65</accession>
    <name>A0A6A6NR65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_291794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR65"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="307" mass="34394" checksum="051BF31C91D7ADF1" modified="2020-06-17" version="1">MEQPNNELMSALSTLLEAGKYSDLSIVCGSKRYAVHRAIICSRSGFFDGACSSPFREAETGIIDLGEDDAEAVEHMVHYFYHLDYLSTNNPRSRRASARSRAGSLRPTSPVSPSSPMSPRSPTRRRAKKLNLALVEDPLLAQAAASVTRPRYDPLTPPEERENQFETSLADKIHASQEEEEDEDEEVVDPFEFVAPEQQPNVDVPYLLVHAKVYALADKYGISGLKALARRKFSTQMAHHFQSAEFPPAIQEVYDSTVDSDRGLRDVVTQTFRANPALAHRKDVEEVVKETPNLAWELFRMAWGMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR71</accession>
    <name>A0A6A6NR71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR71"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="19257" checksum="477051FB90A45B29" modified="2020-06-17" version="1">MPASPPSWALPRRSCDSVGMHFARIQQVAPRITRAYVGPDNRPRAASAAARTLKKREAGMLRLLANAARPQNSSALPHYVSERQRSTGRAVLGGFGSSPGVARNADAAAPRCSDARVRSRRVQDSWSCTAKATGGGGGGGGSGGGDGNAEPQQLCVPAGRGPAGQHQGGSSTVDSPGVEGPPCARSPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRD3</accession>
    <name>A0A6A6NRD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_116352</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRD3"/>
    <dbReference type="OrthoDB" id="5512at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="273" mass="28534" checksum="2F8DF5DDDA5566B7" modified="2020-06-17" version="1">MADRFPSLDEIDAGQTTTRGDATNFDLIGGGGGGGDGPGDASDFLSRERAALGDDANQFASPGDSRLATTVEDAPDGDLDDDLLGGGGTVGGDGAAQEEMRGFEESFPAIDAGNEHMAPGGTITGTNAPYLPGAAAASSSFAPAPMGTPEPEPEVIRAWRERRDLAIKHRDEVSANRKAETIKAAHEAIDDFYDNYNNRKEKGIAQTRREADEFLAAREDTAAGGTSWERIAKLVDLSGKGTKGGGSGSDKARFRELLLSLRKDQNAPGAEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRF0</accession>
    <name>A0A6A6NRF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_113178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRF0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21761" checksum="DBCB4BB8E7F6F94E" modified="2020-06-17" version="1">MARQNTPKTTSSCQHYPDHRRAVTPFQSEWTAHYKIWPIPSKTIVCRIPVMASSLPSRWTYPASISSSWLRGVLLGGDFNRLYFGPIHRNLFAARIRLEIGEEDSAAEDIEVAISGPGYTIIACNCLSEGFGRTNLLAFTMLHSTKSNNEIRKVVFKLLLRVETWQMSQWMGEHHLLLCIAFTRGGYFAIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSG4</accession>
    <name>A0A6A6NSG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSG4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025610872" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14654" checksum="8A47F09DC266D5F6" modified="2020-06-17" version="1" fragment="single">MLWVYGRTSSFSCLFLFCPLLRVFSSSCSVNFLLVCVSDLSHQFCFSYSCLLSSRRFSGVIDRVQRQQRPCSFFFLSSWSRVIWYLPSLSIWAKAAGGPAGGCAGLVKKIMTAEASKLLVTASLEAVRIALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU28</accession>
    <name>A0A6A6NU28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU28"/>
    <dbReference type="OrthoDB" id="3934095at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="232" mass="24133" checksum="6384A3CBBF156802" modified="2020-06-17" version="1">MPLAHASGTSSSSSSTCSASSPPSSPTRLVVSPHPLPPVPPRNHHHTYAPRRTISSSSTSSSSSHDAEIETIPVNVYELDLLPQPLFSRDPPNRNRSVSSPSSSASPSSSASPTRPLPPVAAIPSPTAATATTTVTAASPTASFPWGGPPRHRALRRMLSPPGGASLRQIRARESEACLQRAYEARTQAYLDGTVFSPALAPSQASYSPPRRPRMGAGNGGVVRLVVGVGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU67</accession>
    <name>A0A6A6NU67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_350431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU67"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6743" checksum="1E62EFA5A268EC65" modified="2020-06-17" version="1">MERISGAREGLHTCASRVVSLWGLRKGEFLFHGLDRPLARRSTFGIRKSSKRPRTVLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUU7</accession>
    <name>A0A6A6NUU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_307362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUU7"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF8">
        <property type="entry name" value="NUCLEAR MRNA EXPORT PROTEIN THP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="62590" checksum="2460E343665A52E9" modified="2020-06-17" version="1">MSPTPTLDQFLGEIAAIVSRRDGAQLQDYLIIEPPYGALYNQMITELHQEYPLGKEAFLEDKCAFILAEAQEGADGATWTMFIKFMVQYLTFLRDVNVENLLDTYNLLSELVQKCISALAHPTLGIVVLPTVIAYSRVLARLAIGLDRQPHLIAHLVQRSAGGEEGGAETLPERAANIVRTAFVTCLNDRTANPSGLRDGKPDGKKAGIYTLANLCLKILFQCKKTRNVEQIFSNIYNQSPLLSAYPKPEQATYLYYLGRFMYQNNHFRRSAAALQHAFDLTPPRFVSQRHSMLVYLISANLPLGRFPSENLYNLPEAAGLRELFFPVTRAIVRGDLASFRKLLDLNLLATPSSENTSNLQLVKENHERVQFLFRRRVLLQLRNRCEVLVLRSLARRTYVVAGQEGNVEKRKAATLDLQYYLQALRWLEMKALMPNWVPAGLIENGPSFAAENVQEESDYPLPDIFEAEAVISALIDQGLLNGFISRNLRRFAIVGSKRKGNPLAAGFPPPASILAPAGFDEREEVPGWRREGLLGSHVGFGAPTGSQGMGMGRGAGTNFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUV0</accession>
    <name>A0A6A6NUV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_66528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUV0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21115" checksum="644718EEAFBB63EB" modified="2020-06-17" version="1">MARLERRLSIGARRGLQGLHPSTLALLRAGLAPPQAGGFETSPFAAVPANGRRHPATRPSPKFRISSLWCPRMARTAAMPNARMETPAHDDSFFRPLCGASPPWRASGCTVPCSWTGCLQSLDLRENRPGSLKPLVLPGHKWHLLPPSRWNFSPSLFSSWLTFIPVPLGLPFCSYLVLLLLLFLPVAEHDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV86</accession>
    <name>A0A6A6NV86_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_416432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV86"/>
    <dbReference type="OrthoDB" id="207120at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11887">
        <property type="entry name" value="SH3_Bbc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057402">
        <property type="entry name" value="AIM3_BBC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035552">
        <property type="entry name" value="Mti1_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46026">
        <property type="entry name" value="RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46026:SF1">
        <property type="entry name" value="RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25459">
        <property type="entry name" value="AIM3_BBC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1064"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="563"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="582"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="634"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="666"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="707"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="756"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="775"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="801"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="823"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="872"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="898"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="910"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="943"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="955"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1259" mass="133532" checksum="7C3C2D948D3729FC" modified="2020-06-17" version="1">MASPPFKVKAIYEYNSPHDDDLSFPEGQVITVTEEEDADWYVGEYADASGARHDGLFPKNFVEKFEPAPPPRPVRPTHRQKHSEAAAAPAPPPAPVDEPQSAHGEPQSAKPVEEEHPAPDERPAAAPAPAAPKSPEPRQRELPPAAAATKPGPPPAANKVPPPVAEKPSSFKDRIAAFNKPAAAPIAPFKPGGPGGSSNTSTGFIKKPFVAPPPSRNAYVPPPRAEAPPQKVYRREEDPEIAERQARDLEIAEKAGLAAHDAEAAAATGAAEEGGDAPKPTSLKERIALLQKQQMEQAQRQAASHKEKPKRPPKKRTESHEREGMQPQPPTPAPARESGEMERVQSGEATERESMDSMPAPPPRRQSHQPPKVPDLVPRAGEAFSDGNDADQSAAGETTEDAEGTSTSVDEEEARHKHAPTREPEVGDEEDTTEGDGEEEEEEMDPETRRRMELRERMAKMSGGMGMAGMFGPPGGMPMPGAGASKKKKPAAGEQHRMSEEAESPASPQAQPPRIPMIPVPGMAPMKSPESEETEMAVERDETTPHPVTGGRDPLEVPDVEEAAPRPDERGAPPPLPRDRPAPPPPSAGEPGSPPPVPASRPVPPPDSRPVPPPPQAQPMSPSSGSETDDEMPVSTTATGPSVPSTGEELPHRGPPPPIPTATSPQATRTPMSPAQKRTSYFGTTDSASPTSPAMPAAPGDSKRASRPPPPIPGTSPGPPPPGHARPPPPPPPGAPPSRQPTSESIHGRIAAAKDGEEETEYEGDYDTDIAPGATHKDALKSHARDSSLDDSTTADDAPGKSPPLPQSPTVPPPVPGSAAPRAVPPPPPPGAPPKRQSSEAPRAAPPPPPPPMAGPDEDEYDPYRYAHPATRMPPPPPQAAPHAPPPPMPAAHPQPAEESDGDEDELYANPPPPPPPPVRKSVERPPPPPPQAPPPSHHDRPMPPLPPQGPPPSSSSTAGAAPRGSGRQSLDVNQTLAQGGVSRRSAEQPRPSMGDVQDFIAHDVDLGVATQWWTAPNGAPPVFAGRKDVLVEVEEVRTPTGGIEREVYVLYHDYSQTVVTARFDPRDPGDCEVSQRHEGPPARLRQDQLEDAWARFGRRIAEEAASRQGQVVGDGSPAALVEELLGAGPGGAMSAVRGRALRPVGTRAYGALVYANLANASVQQLDEIRAGDVVTLRNARFQGKHGPMHQKYSVEVGKPDHVGVVVDWDGTKKKVRAWEQGRESRKVKVEGFRVGDLRSGEVRVWRVMGRGWVGWGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVH9</accession>
    <name>A0A6A6NVH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_307227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3548913at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42064">
        <property type="entry name" value="YALI0F28677P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42064:SF1">
        <property type="entry name" value="YALI0F28677P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="813"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1373"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1477"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1528"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1649"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="864"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1380"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1412"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1488"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1651"/>
            <end position="1669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1794" mass="196747" checksum="C4EBDF3F870FD66C" modified="2020-06-17" version="1">MGSRLGRNPVEDERFIANVGHGHVHGHPLRSNSLGGGTPGASTNSYSHHHSAQVVDSHLRPSLPPSASAPAGRLPRLLPHDTSQYTEAYLPTSAVPTSSTSLAELAHLIRLQRYQEQKRNHARVRLHRWLVSSALSARLLHVGELAHRTLVDNFKTDEKRHFATLFNAIHDVRSSCEATRQFALLEPDLELSKSTPSKFSRAAGSGDRIYQNSSSLASASSFSTFMHELPSSTRDEFLTFISEIRTNPDFLAARLTSLSQQELASLTSFRPTLDPIDSVMALQGGRSKGVGSSAQKPTPQVPNPVERLLSFQRHDPLSALIYTIFANSSGPDSAEDLRRTEAWSTACARLIVEAKPGSDKFIKIVLDAWTGMREWPGKANLELYLMQVLQEGQFILDKPDDQFLRSRGQADSRNSKDTIAADEFYERAVKRLFEVIDDEPSAGGIPDGVLELGTAIIHKLEDSSKRHQRIAQTFIVSRWFFSTFLLNAIIHPESHGIMTGYHISEHARQRILKEIALRAHKAVADMTYNWKQHGNVLPEIKTHIENILARFKSNRPHTKPPVLLPAKAITSPRETVEVQPFLVVCPADIYTLINALFPERRPPSSQLDKDLPQQLRQGGGLASGASSMSGASMPFRAPSSATLGANSASAGGDASSILSMSASSVTSDQTSREPLLEPAGRGGEPNGSLFPGSGEVGGNTTKVAPTEEYGRLLRMACSEMSRILGVEATSGTCHPCAERWSVLYVSPDGKELRTRMRKDFEDEDEELDEDSADTDSDEDDDGPAERMQLETDYHLLKENIAKLVEEYEIPKELAPESESKGFSNRTSTIRRDARLDASDSVGNRALPPAEEHAPFSEKPVSKNPYHSQSQLTNLLASTQKGTSSVGASSRHRSSSQHQSPQQHHHHARDEKQSVLITMLEAATQQCQARSDFVNAHLYFKTLQQLRRLSVPSLTRNGYASLLNYFSRGPRDSLSKSATAIEEFEAWFVWLKQSQERHDSTIEDMMLALKNLRDKMWYITDVRNSAVYDEAKNVAVALKVMGQPTKTADGRPIPGVHQQHQRHRNAPKPAASNYLLKTEVQVYDLMAASPDHGGPNKLSDEQSEITSGWLSQYGIENGFCKGEERIHRFCLEVDKCVNKLVAHGIMDGPVLWSSELYRRDKEILDSGRQKGDLFLTGVGTLSIAGDEEYETLPGLGGLGSGGANGGNNNASNNNNNNNNNNARPSSRKFDFIPGSSGTSSTLRSMSGRNGSEQSFDSAKYSSGGHLMDTQDYFGGSSPILTIDSSVTFWSPFQTQAQSPSSATSIRPRTASSSRGTVMLKNSESVNEDKRKFLLDLKQTVTGLLLSDLGTQVFGAGSETDAWFGGDLGEECIQRKEDEDRRRRRSLARKKSMKSMKSAKHVATGDLPHLSAGEHSTSSSDATARSGMSAAKRSGILEFPYNMAFRRLLRKFATHPNPFSKLHALFELEKLIIASLSSRSGRHLSRRETTLPTVSQSPTLGSVPELSSRDPAVSTTRAQNLEEAIANCEERRSHSMNQNGPPSPSPMQQHGGGVTAIASDARSIAVLPSTDMIVDVLQGLFRDANIRPKTLFRDLQYIASFVPSRMLDKSAAGKAFWDAGLAALSLKQDVCRVMVEVVDDIVQLNTKNREANAHATAGSTASAAAGGASEKGANDLSASSASLPPQDPIAKFSMADAARMLTITAREGDAAAQRELAILYMTHPDLVPRMVMPLSKPREVFKGEALSARDRKREDPSRADPVTMCVAHHWMEMSKKGGDQLATKYLRTRDEIEKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVT8</accession>
    <name>A0A6A6NVT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Telomeric single stranded DNA binding POT1/Cdc13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_68245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVT8"/>
    <dbReference type="OrthoDB" id="5363079at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04497">
        <property type="entry name" value="hPOT1_OB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011564">
        <property type="entry name" value="Telomer_end-bd_POT1/Cdc13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02765">
        <property type="entry name" value="POT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00976">
        <property type="entry name" value="Telo_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomeric single stranded DNA binding POT1/Cdc13" evidence="2">
        <location>
            <begin position="912"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1064" mass="116440" checksum="152EC661D99A33FB" modified="2020-06-17" version="1">MAASGEHKGASTGLDSLNTIESLEEVELSKLVPQGEFPTSSRIEGVVTVIWPYFSGRGPTGQGSLAFHLDERENFRCANPGLVRVQLKGRAAREFHQEGLINGFKVRIGLGEATWSEVSTAWSALHFQPQNEKRRVAGELVFTDKVFATIQPPDDESHPKLIDTRELSPETPSPLPQAQEPLPSPPPSATPLPLPKRQLLHDDARPSPAKFRTPRLSTEAALFDFFHDTPIRGEGQRVFSGVRKWIVEGRTPPEEATQAAPVTPTPVQRSPTPTVAEPVTKIMQSAPELVESLPAPLKLPTGLIEPTTAMEPIAKVIESSLELVELPPVPLEPPPAPTEPEPATVEPELAAVEPEPESWEPEPAPMESEFQAVGSPSPVVEPLSRVAEQPPGFRGPVPISQSPGSAEAVPSYSAAVEHGPSPESMQHAPSSPMQIDEQIPSSGGAQQVRDSLPYPSKEPTQKLAQRLESPVEVESEPESRPGWPAVEYPELPSISESLEPIPSEPPLPTYDDRTLPSEKESDDESEESESESEDESEEEFEESEEETEEELIEGEEENEERVGLLDEKSESKQSEVSIERSSLPPVFEGQFEGTERPSPAPLDEGQPGATAQLPVLPSPRAPPSSPQPVSQTTTQIVDLCSDGSESEADVESEKTLVDADKHAQPETHEDTQGLEQRWQELHKHPQGDIHGRTPSPEHPATEALQRSPSLPPDLGMAEDAVAVASQMELDHDINSMPEVTHSDGTSIIERAEVIGKRERRVIPDSVSGSFESKLSSEVSVHEVTEEESQDILRPQDEKLHAIEEDNIMHAEQLPHPTGPEPAGGRSEDLAPFLSTFESTQTTRLQPLDTDDEAVPGGTQFTTVTEYDDFDLPQMALYSDEKDRQVTPTSKHSASLSPAPGSPIGLKTSMGYYTPLAFLPAHLNAHDTIDVLTVVSRGTDTPKRADKGPRDYFTSFSVVDAFANQPVPVKVFRPYKAALPVASEGDVVLLRDVKVRSRRRVCVIDSTEEASWCVWRYGMVGEKGARPPEEMNGPPVELGMEERAEAQKLREWWLEKGMRKWRTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWA8</accession>
    <name>A0A6A6NWA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_288821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWA8"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF104">
        <property type="entry name" value="N-METHYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="35676" checksum="B49FE7C3C363FEDA" modified="2020-06-17" version="1">MPPSLQSLITAQPRTRPSPPHASSRPSAEAEDPADIFASALGSVFADDARDVHGDAATPVEYRAVRVADVVGEEERGRFAHYVWNAGVLVGEVCGGSRKVGTMGRGEGGNGVNGGEEEREKIEGGWWLTEEEETRWSVEGESVIELGAGAGLGGIMSVLGGAKRVTITDYPSSTLLTALTHNITTNVPPPLRATVTTMPHLWGDIHPPSPAACPAHAHAYTRVLAADCLWLSAQHAALARSMKHFLSPRDAGASVIVAAGFHTGRAKVAAFFEEAAPAEGLMVREIWEVDVRSGVRREWRTKREGEGVAERKAWLVLARLGVGVREEGSGEMVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWY6</accession>
    <name>A0A6A6NWY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-xylulose reductase</fullName>
            <ecNumber evidence="9">1.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Xylitol dehydrogenase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_348345</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.9" evidence="9"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWY6"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046526">
        <property type="term" value="F:D-xylulose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="12"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="354" mass="38218" checksum="C1944D462074D714" modified="2020-06-17" version="1">MQNPSWFLYGPGVAKIEDRAIPTIGDSHDVILRIAYVGVCGSDVHFWKHGGIRKVVSPERPLVMGHEASGTVHSVGPDVTSVKVGDRVAVEPGFPCRRCKACKDGVYNLCRQMRFAADPPDTHGALTKFYAAPEDFLYKIPDGVSLEGAVLVEPLAVAVHATRLGSVRPGQDVIVMGSETIGLMCGAVAKAFSANRIILVDIVEKKLEFAREHLKCETFFYDIKSTSEDNATGLLNAFDIADGVDAVIEASGAETSIQSGIHLLKLGGNFVQAGLGKPKIEVPIIDLSTKELHFHGCFRYSSGDYELALKLLSKRDISLRPLISSVTPFEQATTAWDKTGKGEGIKNLIQGVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX27</accession>
    <name>A0A6A6NX27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein transport protein Sec61 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_346732</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Necessary for protein translocation in the endoplasmic reticulum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SEC61-beta family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX27"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006398">
        <property type="entry name" value="Sec61_beta_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="111" mass="11405" checksum="D4E809FE5097ABD1" modified="2020-06-17" version="1">MSSPRPQSPIDSPSTGASTGRQASPKPPGGPAVAMRRKAAADRADKQANARPSSTRSAGAGGSSSTMLKLYTDESPGLRVDPVVVLVLSVGFIISVVALHVIAKFTRKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXA4</accession>
    <name>A0A6A6NXA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_394594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXA4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="35590" checksum="BD6675A5705C1918" modified="2020-06-17" version="1">MGIDKGPSRIAPRRGAALVGRRARRNVRGGARGAEARKFAACGSCGRKPLPMAPLRGGGDAEPETGGPRVCRRGEHPYRGAMLAEPPSRRAAKRRAAAGARWAGCRRRRRQTLARGVAFRLSRSGSWPGYPRPWISRWLAPAFVSVGLPAHGGASAAREPCVAHVSPPVASPDLASSRVLAVLAGDTGVPIEILEPEGRQPPSLPAQLGKGRVGQYRARSARAVCLPSACGVRGDDGPGRASTSSSAVANINDSRAILEGVMEAFWGPPPRPVPVASWTWSSPVSCCLPAPPYPHLSIQLPGCRSTALRRQSRGSQSVIEADTHGCRTLSPFGKAQDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF1</accession>
    <name>A0A6A6NXF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_50455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXF1"/>
    <dbReference type="OrthoDB" id="3545916at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="26077" checksum="4C21FDD25656B48F" modified="2020-06-17" version="1">MVGLELEEKGNHLDASNGHEGESSLQDPSQNIEAAANNDMLQHIGDVTTQGRHKSFSWQSILDENSRLREERNKAREVLQDTQSKLRDSHERLEKLQTEALSSVDRFQPAFDEHIVSRFNDLVQTMKPIGSYLANQKQQIDPRRWGTAVLEYLRVDAINKAAPRFNYDEKSIRKKVLKAVTWQFLENTVFGDPFLCFGTEVAHQAREMYHVFYEDPCRYTSFSVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXR6</accession>
    <name>A0A6A6NXR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA pseudouridine synthase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">tRNA pseudouridylate synthase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA-uridine isomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_347654</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) and at position 35 in the intron-containing tRNA(Tyr). Catalyzes pseudouridylation at position 44 in U2 snRNA. Also catalyzes pseudouridylation of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a uridine in tRNA = a pseudouridine in tRNA</text>
            <dbReference type="Rhea" id="RHEA:54572"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13934"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXR6"/>
    <dbReference type="OrthoDB" id="10256309at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02568">
        <property type="entry name" value="PseudoU_synth_PUS1_PUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.580:FF:000002">
        <property type="entry name" value="tRNA pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.660:FF:000002">
        <property type="entry name" value="tRNA pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041708">
        <property type="entry name" value="PUS1/PUS2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF4">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="17">
        <location>
            <begin position="506"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="424"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="666"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="14">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00036943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00053072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00073968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00079072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00080858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2456595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="728" mass="81086" checksum="843BBEC021FBC392" modified="2020-06-17" version="1">MASESGDAARDEPPKNDNSGQGEQDRQDNFRKRKRDDRGKLKHGSRGKRKNLGRKEYFENQLDRRERNEVEKAKRRRTEEGGGETATPNGPPAFSKEEIEAEEKRPKRKVAVMIGYSGSGYKGMQITPSEKTIEGDLFTAFVLAGAISKANADDPKKSSLVRCARTDKGVHAAGNVISLKLIVEDPDIVERINAHLGPQIRVWGIERALGSFSCYQACDSRWYEYLIPSYAFLPPHPNSFLGKQLREVAEKEGDLQGYEERQKEVRGWWESKEEEFVKPALEKLDPEIRLLVERALFREEITGEGADSSSGSDVADEKLQAPYNDPADVSKELPPGDALAQLSIDTRKELTAGIRTIKAAYIEAARTYQIDDARLARVREALGKYVGTQNYHNYTVGKNGKDPSVKRHIKSFEVDIATVFDDKKREGTGPVKQDGVGSMEENSVSVETTKEKSKESTPAAGKKGVMDQPSEVEVWEAQSEATRVEPETADQTVQPAPVTPAPRVDDKTQYLSLRVHGQSFMMHQIRKMVGMASLVVRCGCPPERIKESLRYDTAISIPKAPGLGLLLERPVFDSYNAKAEEHGRAPIAFDKYEKELVEFKRKEIYGRMRAEEVADNVFYNFYAHVDSYREPIFLYLTSAGIPAAKSRITADPGSKAAIKDRDFKQRNWGKKKAPSKKWQEAPVTGSRTEATTETAGAQEETISDTRVVGGIAGVDSDEETVAVSEEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXV3</accession>
    <name>A0A6A6NXV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_287682</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXV3"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="14">
        <location>
            <begin position="89"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="11">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2456388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="129" mass="14279" checksum="674593743041712E" modified="2020-06-17" version="1">MSASPAPTDEGAANQQGKKIAFRFCRECSNLLYPKEDKDANRLMFACRTCQYAEPAPNTFVYRNDLSNAVGETAGITQDVGSDPTLPRIQKPCPSCSEPEAVYFQSQQRTAETGMKLYYVCCSCGNVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXV7</accession>
    <name>A0A6A6NXV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_386116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXV7"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="113"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="113"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="225"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="52225" checksum="A1A8B8D2A8557877" modified="2020-06-17" version="1">MSELEGRLAQLGLSQYLEAFVSEGFDTWDTVLDITESDLYKLQRAIAEARGYSSDQILPVATPAQSIESNIRSDDSGAEGKPAKPAESAAPSNTGPTGKRKYRRHPKPDENAPERPPSSYVIFSNMVREQLRGQELSFTEIAKIVGERWQVLPPEEREACDKQAATAKERYYAELAEYKKTPQYAKYQEYLADFRAKHGHTQAGEFCIAETPAFRNLTFVRLRRKAVKTRDRNKASRRHIGGGADSFAQSRKRAGSSPPPASYSHATTLPSKSASPANYPLPTINSPRVRDQHSPMSVSPISTTMYKEAPHESSPRMQGSVSQPQRLPHSTSPSGFGGPYQGRRDIKSRRAMRETSPPPPLVHEDTTLSSDSATHSQAQPYQGSLLPIMDSSKAHSRLLPHPVPTPGATPSPLDQRQAIGLPVHPAGPSTQAQQQQQQPHDFRHSTSPLSALLRAGELARDAENQPTGESRQTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXX9</accession>
    <name>A0A6A6NXX9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="2 8">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_345719</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 8">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="2 8"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXX9"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="10">
        <location>
            <begin position="50"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="11">
        <location>
            <begin position="296"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="450" mass="49188" checksum="157A2151338A1385" modified="2020-06-17" version="1">MCIALTSIPNYLSRSFIAFRNLASIYLQFSTPKRLPFSTMASLSSLKKHKVTVVGSGNWGSTMSKIVAENTAAYPNLFEPTVQMWVYEEEVTVSEKSRHYDPGSEFCRGPQKLSALVNGLHENIKYLPDITLPNNVVANPSVEDAVKDATILIFVIPHQFIGRICEQIRGKIIPHARGISCIKGVDVSDQGIQLFSESIGHKLGIYCGALSGANIASEIAREKYSETTVAYDPPPMDSRQPTPVGSPYSSQVDLSKAASKSGPRLHALPADYPPLTHENVKKLFHRPYFHVRMVSDVAGVSLGGALKNIVALAAGWVDGLGWGDNAKAAVMRVGILEEVKFGKIFFADSVRTSTFTEESCGVADMITSCMGGRNFRCAKLAVERGVSVFEVERTELNGQKLQGTSTAYEVNGFLKKQKLEKEFPLLTAVCDILEGKVKPEQIPDLIEPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY37</accession>
    <name>A0A6A6NY37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Shr3 amino acid permease chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_287286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY37"/>
    <dbReference type="OrthoDB" id="5229808at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013248">
        <property type="entry name" value="Psh3/Shr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228:SF1">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08229">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029187">
        <property type="entry name" value="Shr3_AAP_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00786">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="22674" checksum="AC3AAB6913557BB5" modified="2020-06-17" version="1">MPKTNSFATFLIVGPTCFFLGMLFSQFPYDYNVLWAVPPDREPYFQLLENHLRFMHASPPLISRVLHIVMGTGLLGFLTKLYKPSEANMLFDGASLVLYMCGIIVYVANIVKGLRVVTIGSYGQFDIVDGERVPKADAGENGEIIGREDSLRVLAASNTILALVLIGVLVLQAGQWYAQRKEEAEIAEMERAAAEDKKKGKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY44</accession>
    <name>A0A6A6NY44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_49824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY44"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="177" mass="19591" checksum="9510545E707B2747" modified="2020-06-17" version="1">MRAWADRGDMDGSIFTSGVLYDQRMTKKRRLLSLLRPASKLPHDRPHYPQRRALLQSFFFFFFFLCCERAPATFRPNLFLGRWAGSWAVQMARSGHDRRHGRAGMCRTPGPSLLAVSDGELALAARLLSNGPLGALRSCAVPGGAPPGRGSSRAVRWFAPGDARPGARRGALFFCRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYG4</accession>
    <name>A0A6A6NYG4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_386105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYG4"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="407" mass="45033" checksum="B9B0ACEA2B197EB2" modified="2020-06-17" version="1">MKILTKNPLIDGHNDLMILIRFLYKNHIYDDEFTKPFEDGRMAAQVDLPRLDQGKVGGAFWSAFMPCPENGSDFSDENYAPIVRATLEQLDLFQRLQVKYPKYFTPPANSAEARHAFSAGRLISPTAIEGLHQIGNSLSALRLYHTLGVRYATLTWNCHNIYADAALVSNDEGQTVKSKPLWGGISSGPGRQLIYEMNRLGMLVDLSHVSADTMRDVLMGQGARGDGVPSWNGSLAPPIFSHSSAYALCPHPRNVPDDVLQMVRARNALVMVNFSPDFISCVANDDPSGIPDFVEANATLAQVVRHIMHIGELIGYDHVGIGTDYDGIPTAPRGLEDVSKFPDLVAELLRQGVGEYDVAKVVGRNLLRVWKDVDEVAARLQREMLPAEDNIQPLQEELNTEDELPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZJ3</accession>
    <name>A0A6A6NZJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_372388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZJ3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17973" checksum="D0FC336B0B5B58BF" modified="2020-06-17" version="1">MPVQTRSQTLVARQLRELSDNIRRLRQITDDLDFVLGRRIEVVAESGGYSLRFNSETGANEMVYRRPRTVFRFRRIWKPVVQRGRVGRTGAVGRPRAVGGRKGVKKEGEGVVKREEAVVKTEEGVKSEEVKGEEMDEGAEIGVDMGAEMEGVSLDVVKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P022</accession>
    <name>A0A6A6P022_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P022"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="30516" checksum="7D70800582FDCE9D" modified="2020-06-17" version="1">MTSGAAALQPAPTTTVQPAYQEDQYRAQGLQTIYGTAHTFFDTGAQDQQRVFDFGFLYGPYQFAMNPSGQAYGYGGAGPFGQAQGQPTVGADNGAPAGATLPTGNAPPAGAAPPVGAAPSGGAGPSAKGNEPQREQPEVYEAEYVQARPEMFPVLPTDVKDMSRLPPDGTWVPWEDHPNPEAGFREAEQLLRGDELFPAADKQWAEDRLAEIYYEVLIAPFDTRQVGDFTPGATHRAWHFFGEHGRPAEITLLDALRASREFKERAGNTIMSLWMYYGAALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P027</accession>
    <name>A0A6A6P027_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrodipicolinate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_286860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P027"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF24">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G11920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="36268" checksum="5F6BE272E9068996" modified="2020-06-17" version="1">MTTSASDQVNGAANGYSNGQASGSTKPRNPLRPGIYSPTMTFFDPETEDVDLPTIRKHAIRLATAGLVGLVTMGSNGEAVHLSRDEKSAITRATREALDEAGFTDVPVIVGASEQSIRGTIELSKQAAAAGGEYVLLVPPSYYRYAMDEAALYEYYTSVADGSPLPVIIYNYPGAVAGIDMDSDLIIKLAKHKNVVGTKFTCGNTGKLTRVALATNATTTKSEGSGYMAFGGMADFTMQTAASGGSGIIAGGANVIPKTCVRVWDLWAEGKYNEAMEMQKTLSKGDWVLTKAAIPGTKSAIQSYYGYGGYPRRPLKRLSKEQAVAIKEGVREVMELEMSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0C5</accession>
    <name>A0A6A6P0C5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_285770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0C5"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="33335" checksum="0E7508666BDF2520" modified="2020-06-17" version="1" fragment="single">SSLTSLASEVTRGVVENGRRYHSFGNAEYAFPNDDRELDRLDMQHAMQTLLLDNKLFWAPIGSDVQQVLDLGTGTGIWAIDFAEMFPQAEVIGTDLSAIQPSWVPPNCRFQIDDAEQDWTFKPAQFDYIHNRNFVCSIRDWPRLIRQSFSHVRPGGWVEWQEKHPLFLSDDDSLPADGALDTWGRTFFDAGVTFGTSPYSPQHLADQMREAGFVDVREHVLKLPVGPWPKDKRLKHVGMFEMVNMVEGVEALSMRLFTRALGWSPERVQLLLERVRKEAKDRKVHSYYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0C7</accession>
    <name>A0A6A6P0C7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_26138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0C7"/>
    <dbReference type="OrthoDB" id="4509729at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="116" mass="13106" checksum="77755E992D36461C" modified="2020-06-17" version="1">MTQASYPAGAPTTAPYPLPHGGHASAVVAPSAQQHHYEEDRLYEVNQQIKTVLTGLLNCEAVRHGDSGFRAWVQGRLMDNELELKRQRRRRSSVDNREVADFIATHLDHHGFRYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I3</accession>
    <name>A0A6A6P0I3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0I3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="145" mass="16427" checksum="8D4BBDA0F7361E84" modified="2020-06-17" version="1">MRTGAPKRRGRKWKDLEVGGSGSVLVGFGSDGPRRVPIWIQPVTLSCSTIAIHMAQFTCGIILLGHRHCGVQPQFLFVCSDSLLSRYLDVAFWFQCSNRVEHQQWPLSTHSWLLTSPVFLVLFFICFSVRKLPLGCSSSRVWLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0R2</accession>
    <name>A0A6A6P0R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_344168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0R2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="9226" checksum="D3428E6A943B4F21" modified="2020-06-17" version="1">MDRRPLPPVEQAMRRAPLVVPLFSFCQEALREARSRLGGLQQACAGAPEYISSGRTNERAAPALQARLLWPAARQRLKFQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0U4</accession>
    <name>A0A6A6P0U4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0U4"/>
    <dbReference type="OrthoDB" id="3533623at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="538" mass="58793" checksum="BA320F9A9FAB6732" modified="2020-06-17" version="1">MASASHSRNTSADTTASGSSLASILDHVLSYPATYEIPLRTMYTLNCVSRAQQQPGSSAYSRSPSPTAAAAATTAAIAAPPPAPSSSPASAHSQNAPWSRIDPQGSANFTASLMQQLSHSKGQPLSLPPSFITSFVRRAFPVELHWVDFPQALAALDYLKDLEQRRRREIAAALRRLGIDRTADAAGDVLDKSPEAAAWVQEVYDKDRKAEALYSQVYVSLRRWILINEMSLAPFNKHNCMAMLNTLYPPMLAVQPTSQLKPDVLLMQRESFFRYINGVEKNGTDILRNVMQQGKKPEAKDGWSAVHETLDMYLRVANRMIQDCQACTGIEYLIPEEARRKGRKVDSGVSFGSDQSRRPSTSGGSASSGGGHHHHHQNQPSVGGGKPLPAPPKEQQERPRTPGSSLRPETPTSRPYGGAAKGYSTLERIARELKKMRAKHRLEVEEMVHIEAVRPEQPKSPVKSLKKMKSMGALGELKQQNNLGHGRHGSGLTRSDSTSNAGRRNGDVDAATAMGDKKGGVARERRVLFDRKLASHEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P106</accession>
    <name>A0A6A6P106_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_371967</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P106"/>
    <dbReference type="OrthoDB" id="263893at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009542">
        <property type="entry name" value="Spc1/SPCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06645">
        <property type="entry name" value="SPC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="120" mass="12799" checksum="0972F63BF8647438" modified="2020-06-17" version="1">MADAVLEKARDLFEGQIVSTPPPGDGHAGLMAASQDFEGQRLAELITTVVLTLTGIAAFLVGYVTQDIYQTLRIGLGGTALTFLLVVPPWPFFNSHSVNWLPPRGSVAGFDIEVDGKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P153</accession>
    <name>A0A6A6P153_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_363763</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P153"/>
    <dbReference type="OrthoDB" id="5429740at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="249" mass="27592" checksum="881977C3430C7F5B" modified="2020-06-17" version="1">MLGSLSVLSDLYALLLLAALLWRLQMPLKQKIGLFSIFSCGFLVVMAGIIRTVMLYRLAAFSNADATWLGFNLFCCSHAECQLAMICASAPALKVFICRYGGDLAECCGKYVTSLSNRTRHIYHGRGNIAESFNNSLSSVKGSLRSVKGSVRSDRWMLRRKDETPDCERTQEMTVSMSLSKQQEEALQSWRPSRFGPDPNQDYSGTAEMYDTNNRGGNGPPVPPKDEDDFMSNPSSGAGMKEVRIRAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1L4</accession>
    <name>A0A6A6P1L4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_302916</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1L4"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="53"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="105"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="157"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="210" mass="20874" checksum="5AC3DDC28C9B3F28" modified="2020-06-17" version="1">MRQDPEGPEEPAPPETPEEPGTPEEPGTPEEPETPEEPGAPEEPGSGAIVSPDGSCGGTYSLTCVGSGFGDCCSANGYCGTGGEYCNAGCQAEFSNCENATLTPDGSCGGEAGYTCAGSAFGDCCSPFGFCGGSEEHCNAGCQTDFGNCEAPDMTPDGTCGGEAGYQCEGSGFGDCCSSSGYCGDTPGHCIVGCQSDFGVCTTPPEEPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1L7</accession>
    <name>A0A6A6P1L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_371816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1L7"/>
    <dbReference type="OrthoDB" id="2121319at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38120">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38120:SF1">
        <property type="entry name" value="M PROTEIN, SEROTYPE 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="420"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="566"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="641"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="679"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="717"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="833" mass="84475" checksum="66A1FC1465034340" modified="2020-06-17" version="1">MSAASRRPPAPGGSSGSGSGGRPTSTGAPVPGAPGSSGSSSGRSPARASTPSGGGGGGGGPANAAAAAAPAANGVRRAGSVRSAPNGSPISARASVRKPGGGGGGSVGGPSSGLGKEAAAAAGRSGSPSSGAAAAAMPSKAEREAAEEDARAETAALIRDLKGRLAAAETASAELRKQAEVLEARLDEAVGEQARLEERVHEEEERVEMLENGRKEAMRQRRELEAIYEAERAASMKDKEESAAKEDELREVIERLKDGLAKAQKEAATGSGADDDERMSRASTLRANSSPSLDAGGGGGGGGGGGHFAPPASLQRSNSRNNSKLILQKDKMIEQLRLDLAESQIKLVEMENMGGGRVQELERILLETRMTNARLMEDNESFQLLLSEKTLNGDFAAAPRGEAGYGRAESASGAGAAAAASKSASLADELESAAEEDEQQQQQQQQQPHADEGAEAGALVTSPRTPTPGNRRLEQEVANLKSENKALTLYINKIIERLLQHQGYETILYKSDGDAAPAALPAVPNTNKDLPPPPPDKDGASPPQQQQQQQQTAGQSFLQRAKSVAYNATSGKRPRPQSQIVSAHHHHQHPQQQHPLHQHYEPQGNADPATAPRIPLARSQSQRNPSGGPGPHRRPQTADWGPAVHAAAAASTANGSTASPAAANLVGNMYRPPPPAPGAGPASPGLASPRSSFFGGARPSSGSGAPSARLSVDGDEAAAGASRPASGSASEAAAAAAAAAAAAAAVGSDAAGPEGRAASSGSGSGSGASPPRSLAGSLERQGTLTMTGNKIRPLRLVQEAGGPEEEGRKAGSRGSWMGWFNRGVGEGQGGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1V4</accession>
    <name>A0A6A6P1V4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_390692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1V4"/>
    <dbReference type="OrthoDB" id="5309803at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="13772" checksum="6134B90A3965DCA8" modified="2020-06-17" version="1">MAWFSILPENLSFFELWAARIFLFLGLLTIAPWVALIIYDFLLYCWRSLTYELPVCGGRARGKQRPRAPSLTERPGGERRRFSLAMPTSPVSASGSAPGGSGAEWMSLRQRDGTAGGAAGCGGEEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1X5</accession>
    <name>A0A6A6P1X5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_371515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1X5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="18823" checksum="9B0CEA0CDE945D55" modified="2020-06-17" version="1">MPTRPYTPPQLWPPYVRERLRHERILIPWPEIPPRHWIEVKLEAIGIPLPRTLYGQEAAAQDAVSWWTATLRRGRPIRIPTSFSEQASHVMILYMSRSDDRYVPELKVYRVWLEAFKSCMRDGKHAPNPETWILTETDGVFELVGSLCGWQNWQYVVNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2E1</accession>
    <name>A0A6A6P2E1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_284937</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2E1"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="9104" checksum="4B9749B0F72834F4" modified="2020-06-17" version="1">MIIPVRCFSCGKVVGDLWERFLEQINSGVPDGTAMDNLHLNRYCCRRMLMTHVDLIEKLLRYGPVPCVSHPSHVFSDTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2N0</accession>
    <name>A0A6A6P2N0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_213960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2N0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="19353" checksum="865D385591703A5F" modified="2020-06-17" version="1">MYLHGRVLCLGCSPAACRSTSSPPARAYFSLVASASPSAMGNRPILRDNARGTLAVPRPICESLTEAKSRLCASIVDDRDTFASTAPLKVFERRRRRRLRSEKQREASIATGSSSSRWRARTPHIADSPVRPIPRCWGSSLVECPENGPAHWEPFRFRIPRRSQGASFLCQICR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2V2</accession>
    <name>A0A6A6P2V2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_319330</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2V2"/>
    <dbReference type="OrthoDB" id="45882at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF9">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="77"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="378" mass="40182" checksum="7662D10EF579ABC2" modified="2020-06-17" version="1">MTAAVASFRDPSASQQQQQQQPPALTLPRAQFAALAPRHFLAAHLAPTSSSAGGAGGGGGGNNAGSVRANGRAAHAFRQPRLHRGSLTHAAGSAVVRLGDTAVVCGVRPEILRVADVPNPPASAREALEGICADEAARLGLLVPNVDLATGCSPAAAHLPGQAPSALAQTLSARLLNLLHASRLFRARDLRIAYTPPLAAGDADDDAPETRVVAYWTLYLDVLVISLDGGVFDAAWLAVQAALSDLRLPHAWWDPDASAVLCSDDAERAWKLQFRPATPVVSATFAVFEAKEDKRQDKEWWVLVDPDTFEEGLCKEYVTVAVEGAVNGRSGPRIRKIEKSGGPMVGKTEMRQLVDLAASQWQHWRDALLEPDSMNEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3J2</accession>
    <name>A0A6A6P3J2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3J2"/>
    <dbReference type="OrthoDB" id="2147163at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="95"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="312" mass="34352" checksum="1EC2A625E722FB4C" modified="2020-06-17" version="1">MLAPCARRSTSTFLLRTSRSAFSRNNNKAIRPLSKQTLQLSHRTPNRPPLASFPRNLSSSTRTMSGASKACCTVPPVVSEGYKEKGEWVTVDGLKTYATGPASAKKGILVIYDIFGFYPQTLQGADILAHGDSEVPKRVFMPDWFEGKPASLSWFPPQTDDQKSKLGAFFAEVAAPPKHVPRVPIVADELKKLAPDVADWGIVGYCWGAKIVNLSSQAGTPFKAAACCHPAMVDPNDASNITIPIAMLPSKDESKDDIAAWQKGLKQANKVEWFEDQIHGFMAARGDLTDANVKQQYERGYKLLLDWFHEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Q4</accession>
    <name>A0A6A6P3Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_207173</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Its motor activity is directed toward the microtubule's plus end.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Q4"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000031">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="6"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="382"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="901"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="644"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="700"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="770"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="416"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="916"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="934"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="87"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2458606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="957" mass="106571" checksum="68DED84FB21673ED" modified="2020-06-17" version="1">MASSNQIKVVARFRPQNKVETASGGEPIVEFQSEDTCYISSKEASGSFTFDRVFQMDSAQHDVFDFSIRSTVDDILNGYNGTVFAYGQTGAGKSYTMMGSDIDDDMGKGIIPRIVEQIFASILASPGNIEYTVRVSYMEIYMERIRDLLAPQNDNLPVHEEKNRGVYVKGLLEIYVSSVQEVYEVMRRGGMARAVAATNMNQESSRSHSIFVITVTQKNVETGSAKSGQLFLVDLAGSEKVGKTGASGQTLEEAKKINKSLSALGMVINSLTDGKSTHIPYRDSKLTRILQESLGGNSRTTLIINCSPSSYNDAETVSTLRFGVRAKAIKNKAKVNAELSPTELKALLKKAQTQVTTFEGYITSLEGEVQLWRSGESVPKDQWVVPLQRDGASGAGKKAEPKPRPGTPARIQSAEPKSRSETPSRPESRMELERSETPTIPMDKDEKEEFLRRENELQDQLAEKETQMANAEKNLKDAKEELAELRERDTRSSKDNEKLNSEINELKMQVEKINFETKEAQITMDGLKEANSELTAELDDVKQQLLDAKMSAKETSAVLDEKEKKKAERMAQMMAGFDLGAEIFSDKERAIRGAIEHIDALHDAAASSEALSQDDLRELRQKLLETQGIVRQAELSLTERSEHDEALMARRTALEERLAKLQREHEELLEKGLGEADVDEVKTKLVAAYDTRREGQAEVLDEMRRDLDRRGEENVRLRQEIEGLQQRVKAVNGVATSAGMNGKTVQQQLAEFDVMKKSLMRDLQNRCERVVELEISLDETREQYNNVLRTSNNRAQQKKMAFLERNLEQLTVVQRQLVEQNSSLKKEVAIAERKLIARNERIQSLESLLQESQEKLTSANHHFEKQLAAVKERLEAVKAGSTRGMDAAGAAAGGFSFGGSRIAKPLRGGGGDSSAPPQQQQQQHHPVLPVLSGLQAQESGGTPTQAKRSSWFFNQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Z7</accession>
    <name>A0A6A6P3Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_341092</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Z7"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000029">
        <property type="entry name" value="peptidyl-prolyl cis-trans isomerase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000009">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="11">
        <location>
            <begin position="12"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="370" mass="40383" checksum="2261AFA55350F369" modified="2020-06-17" version="1">MDPNALKRSRVFFDVQIGNDKAGRIAMELYNDTVPKTAENFRALCTGEKGEGKSGKPLHYKGSIFHRVIKQFMIQGGDFTRGDGTGGESIYGEKFEDENFALKHEKPFLLSMANAGPGTNGSQFFITTVPTPHLDGKHVVFGEVLNGKSVVRQIENIPTDQDRPKTECSILDCGELTGEAYDKCTERQVDSTGDLYEDYPEDQGDEIPGPEILKISSHLKELGNAAFKAGDLALGLAKYQKGLRYLHEYPAPQESDPPELGGQLNALKVTLHSNSALLQLKLGRLEDASSSASKALEVEAIGAAEKGKALYRRAMARAGKKDEESAIKDLEDALKCVPGDKAIVNELAAVKKKAAERAKKERAAYAKFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4J1</accession>
    <name>A0A6A6P4J1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_385177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4J1"/>
    <dbReference type="OrthoDB" id="5407894at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="57967" checksum="9D2FB226727EDAA1" modified="2020-06-17" version="1">MRSWMDVPTRPPSAPIARVARNLRLPSFDLLGIRVPHPDNVVFSPNNVFADVGSGPLSKPEDPLHAESPLGERPGLEKVSDGGGILPPPPPPPPPTERSQPPAKTSVPKFIPTAFTPPDDGGPLNWDSGAAVQAGAMESPANSEAEQAAQQQGGEASSAAQNPPSALAQFQANSERPWISSALQIIYEHEFRGSFRVLSHALPCPCATGHAFPLVINALHEAIPRQSTTWINVFHAVPGRFNMADLPTSPPNTPGPAIGGEDYFSTQVFDSAVPIIDYQGDAKLLRNAPHPVVPPATIDFSIVERYIPPTNAIEFLDLTTITSRSLLLDRLIELSPHNGTLLFIYPTKTGARTFMDDYLGPIIDPLLRSMTVVNGLTADLGTSLGRMRAVSQMLEFEELRSRLGSFCRRLSTTSSEVLRRFHSTNASYSLVHASRHEVFLDRKVWAGDWWIKQEKQRVRDVVSRYYGTSVKSPSQQEAASGSYWNTSISSPIHNPSKYIQEIIDGVEAKQNPDHQPSKGVEVGVFVLRKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4N8</accession>
    <name>A0A6A6P4N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_283951</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4N8"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="11">
        <location>
            <begin position="37"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="12">
        <location>
            <begin position="305"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="9">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="430" mass="45039" checksum="2EF95CCA86834AE0" modified="2020-06-17" version="1">MAAKPTARASSRLPAAQRCARSFGSSASARREVRDAYILSASRTPTAFNGAFTSVPAPRLGATAIKSAIEKSTVPVERLTAVYMGQVLQAGVGQAPARQAALFAGLPTWMEATTINKVCASGMKAVTVAASAIQLGLADAQVAGGMESMTRTPYYLPRASQQPAFGEQRLADGLVADGLWDVYNQVHMGNCAENTARKYGISRADQDDFAIQSYKRAQDAWAARLFDEEIAPVTVKGKKGDETVVAEDEGYRRLKLDKVPTLKPAFSKDKDGSVTAANSSSLNDGASALVLGSRDVAREHGRGSRVLARIVAYADAAVDPIDFPVAPAKVVPLVLDRAGIAKHDVAVWEFNEAFAAVIRANAKILGLGQDNVNPRGGAIALGHALGSSGSRILVTLLHQLEVGQYGCAAICNGGGASTGIVVQRVGYGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P574</accession>
    <name>A0A6A6P574_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_370446</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P574"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902181">
        <property type="term" value="P:verruculogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000063">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2458928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="543" mass="60322" checksum="E97418069C03B317" modified="2020-06-17" version="1">MPLTATIVAVVAAFAVYIVGVVVYRLFFHPLARYPGPLLAKITGWHAAYHAWRGDRHLEFWRCHEKYGSIYRWAPNSISVNTNTALKDIYGHRANVRKADFYTAFPPTKDTFNTHSSIDRAAHARKRRVLSHAFSDSAIKTMEGHILDHVRALCTQLLGATQKTRSPQLLEEKQAESSSKRGWSAPQNMASWTNYLAFDVMGDLCFGKPFRMLTSPTNRFATDLVASASHRHLICGTYLPIHKYHLDKLLFRRIAAGRARYMAYSKAQAGERAKIGIDGAPDRRDFFYYLLQARDPETGAGFAPAELWGESNLLIIAGSDTTSTAMSATLFYLAHHPECFAQLARDVRAAFASLEDIRLGPALTTQAYLRACIDEAMRLSPSVGGLLPRTVLPGGLAVDGHFFPPGTDLGVPHYAVHHNEAYFAEPFVFEPSRWLPDEAAGGADAVARAQSAFCPFSIGPRGCIGKTMAYAEMSLTIARLVWAFDLRLARGEAGRIGEGGWGEAGREWGREKRGEYQLKDTFTSWKDGPMVEFKLREGAEIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5E4</accession>
    <name>A0A6A6P5E4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_275531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5E4"/>
    <dbReference type="OrthoDB" id="4505928at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42070">
        <property type="entry name" value="FILAMENT ASSOCIATED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G06630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42070:SF1">
        <property type="entry name" value="FILAMENT ASSOCIATED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G06630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="7438" checksum="E134840624917EA5" modified="2020-06-17" version="1" fragment="single">ARIRDNQRRSRARRKEYLQELEGKFRNCQQLGVEASAEIQAAARKVLEENKRLRSLLRQKGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5F4</accession>
    <name>A0A6A6P5F4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome 60S biogenesis N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_340166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5F4"/>
    <dbReference type="OrthoDB" id="72892at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059018">
        <property type="entry name" value="HEAT_URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039844">
        <property type="entry name" value="URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021714">
        <property type="entry name" value="URB1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500:SF0">
        <property type="entry name" value="NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500">
        <property type="entry name" value="NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26140">
        <property type="entry name" value="HEAT_URB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11707">
        <property type="entry name" value="Npa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="URB1 N-terminal" evidence="2">
        <location>
            <begin position="90"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 central HEAT repeat" evidence="4">
        <location>
            <begin position="635"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 C-terminal" evidence="3">
        <location>
            <begin position="973"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="913"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="915"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1229" mass="140159" checksum="317E9D852328EF26" modified="2020-06-17" version="1">MPPKRACDAPLDRPDKRPRLEAETITSSSQLKLILNFDETALERLRNGLHSFKVFLDSILYSSQDNAILKEYLEKEKPTATAESDDAYLADLILTLKYASEKSVGYLFSSVVADLALLLRAIGANFDLLQYGRLLCATILSPENVKLIGRGLANQRVDPRIISPCLRLLTEIVSFDGGAFAEQVYRRKEDTYNFQVLSRNLKQGHFPTGPLDEARQGPTIRSNAVRYLLASLKFQGSSQRIEILKQGKVLGVLFGMLPSDPPELAHEIISELDKIVANNPKVPQSMKEFVFFEKNLQHILELGRKPRTRPPRDKELRKLAMDVVFEHCTTEGLSLLKSPSSWYPPNYEDRVMNPFFGPDNAVINLGLDNIPGISYDGKIPVRNSTLASFIRHLRPNGRENNQQLLLAIFKNCPELVAHYFLECNEFEYAPRHSMVYASYATFITSIVELPMPPHFGKESDYSAVPPPAEIVIENIIPRSLKKDVFTRCLNLPEEKYNDFAIQVLKAVLTKSRDIFLIFDKVGPSRPDPSLWRQASQRLMSKVTQRIPHLKDVITYFRRLDREKDVKRVDAEAVLSLYYEAVPDLAFSVKFDISRPMTEALTNVEVFFPHKIDNYYRKELCIQELHNLVNIALRDPDIDWWRCQKGMKLSPFVSLLRAVVFSYTDEKAVGIGNLLGPIVEEIPIVQLDTAPHSSIDALVRSLKPLDTWSPSEAVFRFLSTCCMRCATQPVKYQDLAQRTMKELYEYSYMEKEGGPGSMLLMTIHEQWMYILNKAIPPTKKEDFKVPEPIPHRREGRRDHVGVLAEVRAINWNEDARYEREKEKTIRNAKEALKGMQEDFGIASADDLRHITKWVGRFLRLAKLAGEDESFVEYIFTKLRSWCRAHQAIIPGLEKAILPTFFDKNLDFDSEELITDSPQKSKSRSPPAKSSTPPGAKLDEFMSKPIPTESDDHSGLLRWARKDLVDAIEDGAVGELVVCSCSAHLAIRKEAMTQTKQLIERGDKIGSEKYPEWEMISLILRVVLEKVRELGDGTPLSYFDGAFVERALRILADPNHYLYRKMCAFIMRGPTWKTDRLAGYWTNRVLSDLPDPPADNPDGWRRGFEWLLDWFVDGLRGGDNPSAVLPWWVIEKILVMNDFISVTERLRYKILQLLFRVAAVGDGAEYLIKRLGILAWLKIRAQVESVAMYRQLGRLAKLLTVKAQGGSVEEWAPGYLEGQAWRMGMKVLPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5I2</accession>
    <name>A0A6A6P5I2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_283400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5I2"/>
    <dbReference type="OrthoDB" id="47801at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23837">
        <property type="entry name" value="UBCc_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057735">
        <property type="entry name" value="UBE2O-like_tSH3-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23046">
        <property type="entry name" value="tSH3-B_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="756"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="592"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="688"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="688"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1010" mass="112014" checksum="0B1E07089017350E" modified="2020-06-17" version="1">MLGPVFCADDACALKADPSQLLVIDRSPAAVHTHEPSPQRDYQHSLRRDPSVSEHDYESLMRTGVPPRGTVVVSWIDPNKRDTAHIAESALILIDRPLVLGDIVKKDPQSPLSGAVMGFRQRCDLKPVWPLNSDRRVRDVPIEELESAHDFLYDDMVVYGNWVGAVTNSHDEVTVMLDNNTVVVPEKPQDLQPPSGGLSREREDVGNRIKTVKGNLRRGRWIFGAFNPNVEPVGTVVQSRVLGITVHWLATRPLLANAIPGAFPESVPPDYLDTDVLENVKLYIPQKKAGNRPADWWSDSLRTMQLPRSAYGVSLEMRMKFVNLDEACQKYPGLSRIPRASTMGFDMNVFSVQSTRTEVLVQWQDRTVTVERAMDLIPEQTVDDDHAVWPGEVVCTVEQASRNVASFAFGGDGPDAAYFEPSKVGVVQSVAGADRIARVRWFTKPTVRFYEDDLLPDSHLGELGDAVEEVSLYDIQTTRGLTVHMGDRVVLGESALKQHNFPIAGDDINWFGDVVALDLDGQVTVQLGLMEPVREVKCMPEQLTVIDEGGDMAGDFDGSDSEDGLDDELDEELDEAMIDIDDEVLEQWYEDEEGHRLEHNEESASEDWSTEDDNLDDGDVDESSNKGTPQSEADTPVTDIKDSSNASLHGEIKRPANTPKISKQEPTRDNSKDSQLELAVLAHADTSPSTILPSVSSNSHTASVPNANTDSTTTPEPRTLSFKDITDAPSPFAVLDSEPPSSHYYFSRPAGDASPTRMRRIAKEHKILRNALPDGVYVRSWETRMDLLRILIVGPLDTPYELAPFVVDMHMGASFPNSPPEAFFHSWTGGRGAVNPNLYEDGKICLSLLGTWHSDDKGEAWSPAKSTVLQILVSLLGLVLVREPYYNEAGYQVRIGAPDTRLPSALYSERTYFASRRFITHVLSQQVPGVNDIIRWLYVDRHEGCPRLVDWAVERANAILERSNGDGAVSEEKRDGLHRISRGAAIPLGRWVKEMENWIKGEAKGEGGQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5V1</accession>
    <name>A0A6A6P5V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_413954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5V1"/>
    <dbReference type="OrthoDB" id="3645574at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="52047" checksum="439E98C59F05F9A0" modified="2020-06-17" version="1">MTSTTTKSLPLIRSEITFEDAVESDENILQELSYPADRLAFCVYLLDHQKEIEAIVSHHLRLSKSQSYNFCVPVYIDNWSKRVLIRFPLPYKIGETRFPGNADEKLRCEAATFTWIQENCPDVPIRFLWGFGFSDGQSFSALSTAPPYLRWVEYFRRKLLSFLGRPVPCQYIGHRNPRPLKTGYLFMDYIDDSKMLIESWEELRHDQTRRANLFRGLSRIMLSFARVPLPRVLSLSNRPLTLRLHALENEGVPTNIDRDLTYPTVEPFRRRPFLFTLTDLHPSNIFADTDWNIKCLIDLEWACSLPMEMECPPHWLSNRGVDQLTDEYLTEFNELREEFMSAFESEERLLCPADEQALLHTSAMKRGCENGNFWYFSALESTRGLYNIFNQHMRPMFVSSNDTEAETFDRVLSNYWSPKAAKTVAAKLKDKETYKSQLLEVFEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Y3</accession>
    <name>A0A6A6P5Y3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_189978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="341"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="862" mass="95863" checksum="D05A0F6C6D9BE1C2" modified="2020-06-17" version="1">MARRLRHDEYTVGWVCALSDEFTAAQEMLDEEHQVLPRNGNDANIYTLGCIGEHNVVLACLPAGLMGIASAASVATQMKATFPAIRFGLMVGIGGGVPGKEADIRLGDIVVSQPGRGHGGVVQYDFGKSTPSGFELTGFLNAPPQILLAAVTKLRSNQDRGRNSLSPHLLKLSSLRKFARDKAGSDVLFEAEYNHVGEDTCALCSATEKVQREERTDTSPVVHYGTIASGNRVIKDGVERNKISSDFGMVLCFEMEAAGLMNGFPCLVIRGICDYADSHKNKRWQPYAAGTAAAYAKELLLVIPAADIVKTQTIDEATREQMCRFYLPLLRNHQFVGRGAELDTLEQKLLVDRNCQKVAISGLGGIGKTQVALRFVYHFKESRPGFSVFWVQALSMETFEQGCMEIARALRIRRGQEGKEDVKQIVQQRLCEKTAGGWLLIVDNADDLDLLRGSEQTEGLLAFLPQSEDGLTIFTTRHGEVAQHLAGSDVVEIGKMTEQETMDLLEKSLVRKSPCYNHEIAMDLLTELEYLPLAITQAAAYINTNKSSISEYLRLLKNTEHDAIVIVSTDFGDKTRYQNLTNAVAKTWTVTFNKILERNTLAADLLAFISCIEWRAIPYSILPAAYPEASLAGAIGTLCSYSFLERRDDGAKLDMHRLVHLATRIWISQNGRKVETSRMALKHLSEVFPSADYSNREIWRDYLPHVARIDRDEKCQDTKEESELCLKVGRCLYSDGRIKEAVLWLQESYEWRVRNLAENDADRLASQHNLAVAYEANGQVKEAVKLLEHVVAIXXVLAEDHPSRLVSQHNLAVAYQANGQVKEAVKLLEHVVIVKQRVMAEYHPSRQLSEELLTALYHSNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6C6</accession>
    <name>A0A6A6P6C6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MED9</name>
        <name evidence="9" type="ORF">BDY21DRAFT_370092</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6C6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011425">
        <property type="entry name" value="Med9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07544">
        <property type="entry name" value="Med9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="24448" checksum="55455E009F08821C" modified="2020-06-17" version="1">MTTTPTPHHPTSSARNTPSFSLPAPGTAHQHPSFQSGSTEVATSYHSSQQHQHQQHQQQPQADTASTSTMPPPSTFDVLPPLHSLLSRLLFPPPGAEPAADTKAPPAPSAANKTSPLTGAGAGATAASSAAATATSTATATATATAAAAASAIAQGGSAGARGELEGGALEIQQLGTAAAAVRLRLARARAAVRGLPDVERSVGEQEEERRDLEGRIGRLVGVLEGLRERGGGGGDVGSGEDGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6K3</accession>
    <name>A0A6A6P6K3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SprT-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_282486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6K3"/>
    <dbReference type="OrthoDB" id="20772at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035240">
        <property type="entry name" value="SprT_Zn_ribbon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099:SF0">
        <property type="entry name" value="GERM CELL NUCLEAR ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17283">
        <property type="entry name" value="Zn_ribbon_SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="2">
        <location>
            <begin position="137"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="42774" checksum="5E7BBEAB278E9F4E" modified="2020-06-17" version="1">MLSSSPPRKNSPHKSKPNRPTTPPPSTPPTSPSKTKLISPSKKGRIPPTPHRPSNEAFWNQAFTNDWNDEYSPRKKPESPKKQKFGKSGPGSGPDSEETSMEPKAMQKSPTKRDRKAIEARKQFEIQKHALADTFLKELDDKITGGKVAEMTKEKGGVRIVWSKKLNSTAGRAHWRKEGKKTKGVDGTIVAQYWHDAWIELAEKVIDDEERLINVIAHEFCHLANYIVSGIKDKPHGQQFKAWGKKVGAAFGGRGVEVTTTHSYKIDYKYIWACSKCGHEYKRHSKSIDPKRHCCAKCKSLLIQTKPVARSAGPSEYQLFVKAHFQRVKKENGGASHGAVMEILGRMYRESKAGKTEPVSSVDGAEDIIDEVVKAVEVITLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6P1</accession>
    <name>A0A6A6P6P1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_338439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6P1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="6595" checksum="2A7575789BE1FD96" modified="2020-06-17" version="1">MREFFKGETSCIRLYCRDCSFPANVIWYHARKGQCPTLPPAPRSWFPIASYMSTYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P760</accession>
    <name>A0A6A6P760_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nife hydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_281060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P760"/>
    <dbReference type="OrthoDB" id="1009at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.645.10:FF:000005">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="6">
        <location>
            <begin position="225"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="495" mass="55639" checksum="29AAC79D78C5BB7E" modified="2020-06-17" version="1">MPVTAVRLTAGRAAAQRAWLSVPRAPRPAFFNNRRQPIAADAARGISTSLPRHYAASAEATSEPDPFKDVGNLRLFNIDHQLGHPVNPEDPQHMNVAPEDGTDPKQRKIRHYTVNFGPQHPAAHGVLRLILEINGEEIVRADPHVGLLHRGTEKLIEYRTYLQALPYFDRFDYVSMMTNEQVFSLAVEKLLNVEIPARAKWIRTLFGEITRILNHLMSVLSHAMDVGALTPFLWGFEEREKLMEFYERVSGARLHAAYVRPGGVSQDIPIGLLDDIYQWATQFGDRIDETEELLTDNRIWKGRTQNIGVVSAADALNYSFTGVMLRGSGVPWDVRKSQPYDAYGEVEFDVPVGVNGDCYDRYLCRMEEFRQSLRIIHQCLNKMPAGPVKVEDYKISPPPRAAMKENMEALIHHFLLFSKGYSVPPGETYTAIEAPKGEMGVFLVSDGSERPYRCKVRAPGFAHLGCFDQIARGHMLADAVAIIGTMDLVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P772</accession>
    <name>A0A6A6P772_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DUF250 domain membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_338887</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P772"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="47"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="45633" checksum="717F9F64F7A36102" modified="2020-06-17" version="1">MEKERQSGEQPREQALQPPGEQQQTLPTVNPAVQPKPQAEQPLLHPAFYVALWITLSGSVILFNKWVLHTAKFEFPVVLTTWHLAFSTLMTQLMARFTTKLDSRKKVPMTGRVYLRAIVPIGVLFSASLIFSNLTYLYLSVSFIQMLKATTPVATLFAQWSLGLSPPSLSRLGNVSAIVVGVMIASYGEIKFVLIGFIFQMAGVGFEATRLAMVERLLSSAEFKMEPLVSLYYFAPVCAIMNGIVAIFWELPRLTLADIERVGYFTLLANAVVAFMLNIAVVLLIGRTSSLVMTLCGVLKDILLVVASMVIFRDPVSGLQMFGYSIALGGLVYYKLGADKIKGHVAQANMAWADYGARHPALRKVLVFVAVLFVLMLVLGGLHQNLPEDYVRKADEAALERLHRIYGDETPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7J4</accession>
    <name>A0A6A6P7J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7J4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="6423" checksum="B977DE349C61ED6F" modified="2020-06-17" version="1">MASISISAAHGWSHEHRPACSSARRSPLQPYHVHHHVYCNALGRLWLEPMACLAVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P873</accession>
    <name>A0A6A6P873_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_337544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P873"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="16898" checksum="12C258D7630B0724" modified="2020-06-17" version="1">MFRTSLGASRSLPVLRLRVVRIVSLASNGVLECAGCGSTGARLQSKHIRSYHSCMKICTPGMRMAYLWGGSWLYKSSSFLLLRSTIAFWVTGYSIWTDANLENLLVASRNRVDPISELQDCRMLGSDGVLITGSGLIVPWIFRAPGPFALPVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8B9</accession>
    <name>A0A6A6P8B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMMECR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_281842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8B9"/>
    <dbReference type="OrthoDB" id="24630at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="entry name" value="Hypothetical protein ph0010, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.150">
        <property type="entry name" value="Hypothetical protein ph0010, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00296">
        <property type="entry name" value="TIGR00296 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="2">
        <location>
            <begin position="93"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="304" mass="32519" checksum="8FF73CBB924351EB" modified="2020-06-17" version="1">MATQAHCAYCFETLASSLEKRPALSLREIEDLWEQYNGPSTDSDSAPELGLGGSSSRSSLFSFSRPSSSSTTPASSAVATETGSSGSGDGGSGGAAAGSKKRKHALASVMAAARAGAGVGGGAGAGAEGAAGEHPLFVTWNTVSARTGNKSLRGCIGTFEPHELEHGLRSYALTSAFDDTRFSPIGIRELPSLECGVTLLTDFRPIADPLGWTLGEHGLRINFTYHGRRYGSTYLPDVAKEQGWTKEETMVSLMRKAGWSGRRDEWRRVGDLSVITYKGKRADLDYLEWREWRDWVDKGAKVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8G6</accession>
    <name>A0A6A6P8G6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_281337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8G6"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF61">
        <property type="entry name" value="CAPSULE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="1">
        <location>
            <begin position="207"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="487" mass="56240" checksum="B3457F254E6E1EB3" modified="2020-06-17" version="1">MAGKQLPQHPIQFLAEKLSAEFEAMLRRQSKTVEEAISEYRRRYNRDPPAGFDKWFDYAKAHDSLIIDDFDSIGSSLEPLWKVEPAVLRESVHNARTHGPQMGGFAIQDGEFQRVSDWMAEGMRDLLLPVVSDLPDVEVAINLLDEPRVLLNNPRTSSNVKFDDHSHQHAWSEITDSCIHGGPKTEGAPHQLSFENFGLSFIGDIEGSKDLCLHTEYHDLHGFFISPTTLLYTERAVPIFSQAKPSTFGDIVYPSIYYIDRLGEYNEDDDLPWEDKQRTLYWAGSTTGSQASDENWHHHHRQRFIAMAQHLENTTNTFLTEVSPGNWQTYKSREILSSLYDAKFTAIIQCSYEQCAAEKSYFQPGPREDKKAGYKSRFVFDIDGNSFSGRYYTLLSSRSVVMKQTIFQEWHDDRLFPWVHYVPVSLQMDELPESVRFLALTEVGDAISRRIADAGRDWSRKSLRKEDHAIYLYRLMLEYARVLRDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8P4</accession>
    <name>A0A6A6P8P4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kynurenine-oxoglutarate transaminase 1 mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_163316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8P4"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="40"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="429" mass="48310" checksum="54075D6233E69EB4" modified="2020-06-17" version="1">MSSSAPLRDPYKPAARVAGQRQDVWSIVNEAAAASPMQPIVNMGQGFFGYNPPQFVIDAAKLALDKVDCNQYSPTKGRPRLKKAIADAYSPFFGRKLDPEKEVTITTGANEGMLSAFMGFLERDDEAIVFEPFFDQYISNIEMPGGKVVYVPMHPPPNGAFETSSAGEWTINMDALEAAITPKTRMIVLNSPHNPIGKVFSREELLAIGAMATKHNLILLSDEVYDKLYYVPFTRIATLSDDLWQRTLTVGSGGKNFYATGWRVGWLMGPEHLIKYVSAAHTRICYSSVSPLQEATAIGFEEADKYNFWEESKKEMKGKMDKFNKVWQELGLPYSDPEGGYFVLVNMAKVKLPEDYDFPPHVAERPRDFKLSWFLIKEVGVAAIPPTEFFTPENAHIVEDWLRFAVCKNDEILETAMERLRGLKKYIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Y6</accession>
    <name>A0A6A6P8Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LIM-domain binding protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_162026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Y6"/>
    <dbReference type="OrthoDB" id="774557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029005">
        <property type="entry name" value="LIM-bd/SEUSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10378">
        <property type="entry name" value="LIM DOMAIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01803">
        <property type="entry name" value="LIM_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="36886" checksum="A4D4ADBFD3720C8B" modified="2020-06-17" version="1">MPHGMMRFNPQQAQQAMRLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGQGHPHQQAQAHAAAAAAAAAAAQAQQAQQAQQAHQAAAAAAAQQQGAQAKMSGNFVLKVLQFADHLGRFSTEERINDMSFWKSFVAQFFSEDGLFRQHVWDQETRKTKQFEICAAALPRYFWTLFNSGVENLQVQVEGAKEGQAGMHSVECAKARFVYWFKNGTQLIWTGKLKAVFGTLDKMDSLEFQTENHKQYLPRASLERLFSVGSPNMSKSPRMSKNMKQNRQQKQMQQQPAEPTLALSELPEAPVNAFGVTNKVQWFLEVCNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P910</accession>
    <name>A0A6A6P910_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_162754</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P910"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000065">
        <property type="entry name" value="[Pyruvate dehydrogenase (Acetyl-transferring)] kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="305"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="109"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="439" mass="50013" checksum="DC9C7D150FC12BF2" modified="2020-06-17" version="1">MSWKASEKLMQSIKHYSAFPATGVSLRQMVQFGEKPSTGTLFRASQFLSEELPIRLAHRVEELDNLPDGLNEMPSIKRVKDWYAQSFEELVNMPRPSLSKEVRERLLKGSKQNGKNSNILSKTTHNPSVERGQYQSAPKVNGASNGVDRKPTSSRRYYAGVDDGMEWPPEMNGYNIQFARTLEKIKRRHDSVVTTVAQGILEWKRKRQRMQIDHNIQAFLDRFYMSRIGIRMLIGQHIALTEQRQRPDPNYVGIICTKTNVRELAQEAIENARFVCEDHYGLFDAPKVQLICPPDVSFMYVPGHLSHMLFETLKNSLRAVVETHGQDKEEFPITKVIVAEGKEDITIKVSDEGGGIPRSAIPLVWTYMYTTVDRTPELDPEFNKSDFKAPMAGFGYGLPISRLYARYFGGDLKLISMEGYGTDVYLHLNRLSSSSEPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K4</accession>
    <name>A0A6A6P9K4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_361585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K4"/>
    <dbReference type="OrthoDB" id="283575at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17178">
        <property type="entry name" value="SECRETORY GRANULE PROTEOGLYCAN CORE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17178:SF0">
        <property type="entry name" value="SERGLYCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="424"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="467"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="584"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="649"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="649"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="788" mass="81825" checksum="1A00A5149D7EF1DC" modified="2020-06-17" version="1">MASGFQGVQVHIETAQSIESQLRPGEVLRLRDHRGRVMCRQYSIPQEQMPGIQAVTPASRRGPSSYYSQNSFVSPIREEAEANARNGSFASSNVLPSRSVSYYMDDPAVSPNTDEDPALGSEHGSPASTHDDQSGLVRKASLGQRHKASLTTIHDSKGKKAALRTVPSATVGAATGYVGASHNSSTPVIEHARAESLESGRDLSSGTGLLDPSEEDSPVTDSSNNALARDAAGARSPSPETPIEHKVDQILRGLERGGAIDAVDAQTAQTLQRKASMSDRQPTYAEQAGGPRKRPPPLNIDAVRAAESRGSLTSLPDLIRRATRLASNLDRGRTASRLGMDWFDSNSVKNYGRSAGDRQSGSLSDILASFPPPGPATPVGEKGVGAAARSASNLGFNQTLPQLLDGEEGDKDGRRRRRRCCCGLPLWAVILIAVIALILVAAAVVLPVYFLVIRKNDNSDGGAASAAVMACQESQPCANGGSSIANADGSCSCLCSNGFTGDTCTVEADAACTTTDVGGSSDASNATVGSSVARLLRAAEDDFNVPLDAEQVLSLFSQNNLSCSTQNALVTFNGAAQRRRRARRWAERGRGLGLEPRQNDDDDDDDDDDDDDGGRTFDDDTLPTAIFPAPALTSNGLIYAASTRAADASSTSTAAPAPTGSGSAAPTRTGAATTASVSASATATPSSGTGSDEDADAPASRNATVLDFARVSVLFVLQETRALDAAVGAQGQLQAFFSSVEEGLEDDDDGGDGAQVATSVALGEGFVVDFERLVITFGDGEEVGGTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA35</accession>
    <name>A0A6A6PA35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_130782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA35"/>
    <dbReference type="OrthoDB" id="3801542at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="670" mass="73092" checksum="FAF2515DB60A7426" modified="2020-06-17" version="1">MAFAIGPPGGHSRESSPERFSEHAKFTPRVSPSEHFATGRTPKNQICVYTWLKDSTGFPWLKTSEPFAESVYPIAAHAAEARCQTGYNCGNGCVCSHPKVYRPAQSLSTPEVDDQTSADEGGYWSAVADFETATLPRIDSNKSFKGSDIKFTFPPSKFDQTFSVQCSGYLFRDADSDPGLLGVSNMVQSSYSSSTSSKHMSEDSPRRSRSSGRRPESVQGQAHESSPSPSRHNMTETSAKTATLPLRPASKSLPSKPNAAASEGRTIACVIGRRTIPVILKNAPCLSLLQYCWFFPGANLTHRTCPGGYNSQGNISSQGPTSSGCSSKSHATSTSQFPGQASNANNDLSEQPAVEAADSESGSDQRMMFACPFSKNDRKQYEKVHGRCTYPPGFKDIGELMDHLRAEHSAKRRCPKCRIRFDGSKQKAAARRAQHKLKCCKGKRRKPNEAEWMTSDQEGLFNQRFIKQKTDGCEKWKQIFHFLFPSTLPIPEPHYDMYVLRDKVPSAESKQAQAPNIGNGVSPFSLSPTRDLRLYETIPALETDVSALPPDLSGMPQITLNNLQGTPGVLVTSSEPSINLYRTPGTQSLSTVAPSMAAPQGTWGNQQMYPSPAHQGGMPMMQFGDDAFLVGLPPPPGHGVVETNFQLDQSGQDITGHQAPDTAWPNESFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAC2</accession>
    <name>A0A6A6PAC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_314698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAC2"/>
    <dbReference type="OrthoDB" id="497380at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="107"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="664"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="707" mass="77908" checksum="EE244437D4DF50EB" modified="2020-06-17" version="1">MAGVKRKQVEADKLARASNSKKIKATNSQTNSKKTAPPPADDVTESDTSEVEHGFYGFSAKDSDVESESDFEGIASDEESEGAKDNTAVENPIRRQGVKGPLVGVDKANTNLSTSSKEAHAKQKALAKERKASKPNADLIQRSKYIWERLRVKSSVPKDERRELVKELFEMITGRVRDFVFKHDSVRVIQCALKYANMVQRKNIAKELKGDYKTLAESKYAKFLVAKLIVEGDDDIRDMIVPEFYGSVRRLINQPEASWILDDIYRGAATPAQKAILLREWYGPEFAIFKTSKTLEPSDGILSNILFESPEKRKPIMSYLYNLINQLIQKKMTGFTMLHDAMLQYYLNTAPGSVESNEFLELLKGDEEFDLLKNLAFTASGAHVVCLAFARGTAKDRKHLLKAYKDTVEMLAYDQHGHMVLVAALDVTDDTQTSTRSILTPLIGKDPPPSNPDEAAQQQAKILALASHGHGRIPLLYPLAGAQKWFFPEQDAALLAEIQVARATTSKKDPQVRRREVVRAISGPVLATIAARSAEFLRDPFACHMVAEVLLEGDGDKNAAVNAVAALAEGDPREEAHIANNAAAGRMLKTLVLGGRFDAESGEVKLVEPRLGFADTLWGKIAKWMIEWACGPSSFVVVNLVDADGFEGREEVLERLRGARARLENAASRTPKADVEKGKVKGGKKKGDKGAARNAGAKILLQKLLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAF7</accession>
    <name>A0A6A6PAF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_406142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAF7"/>
    <dbReference type="OrthoDB" id="2400485at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22927" checksum="6A79AF206E534F70" modified="2020-06-17" version="1">MRPFVYSCTRVDPLAPSRSLSPQRSLALKRKMSTDLNIESTDIQYASGVNLSADQKTVVGCVLDLFAGKPSLQKLKLWEDDAVFEDPLTIAKGRKQYEPQWYGLQSAFSKIERLAHEVTSVGNPISMNLTNRYVMKGLNKEQTINSVVDIYVNQSGKIERVEDKWDGNLPDSSFRNAFRKLNAVSVPKMVGVPKTEEEDARRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC48</accession>
    <name>A0A6A6PC48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">General stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_296801</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC48"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF26">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_4G05870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="33378" checksum="FC92743342CD2BF7" modified="2020-06-17" version="1">MESVKNAAKSATDSGSQFKPGHKVPISDQQPPGLESELKGPKPQDENVPTEDGGYQRYKAAGKLSGKRAIITGGDSGIGRATAILFAMEGADSLIAYLPDEEKDAQETQRRVQAEGRKCVLFPTDLTSSENCKKVVEKALAELGGIDILFNNHAYQMMVKDIQDLSEEQWHRTFNTNIHPFFYLAKYVLPHMGDGSTIINNASINAYIGRPDLLDYTSTKGAIVSFTRGLSNQYLSRGVRVNAVAPGPVWTPLIPATMTHDAQDQFTSPMGRPSQPSEIATCVVFLASTDSMSVSGQTIHCNGGVIVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCD2</accession>
    <name>A0A6A6PCD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_314038</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCD2"/>
    <dbReference type="OrthoDB" id="25826at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000132">
        <property type="entry name" value="FMN dependent dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF75">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_4G07050)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="335"/>
            <end position="339"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="358"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="420" mass="46439" checksum="6741C5595C0B1314" modified="2020-06-17" version="1">MDKYNPNKSIRATPEYAQYQRENFMKLNEGEIPPFNTEPGKLEELAREKLTQSGWLYASSNAGQSHTHTANRQAFYRHRIIPRVLLDTNKRDTKTRIFGHEVAAPIGFAPIGINKIYHAHGEMPVAKVAGELGLPYCLSTAGSQPIEAVAEANGAGLRFFQLYMPHDDELTISLLKRAQKSGYEACILTVDTWQLGWRHDDVNSSNYAFYRGIGAELGLSDPVFRKRLVEAGIDPAKDPVAAGAKWIDGTWHGRAHSWEKMPWLIKTWKDISGGKSFCLKGIQSVTDARKAVEVGCDGIVVSNHAGRQVDGAIASLDALGNIVKDVGDKTYVMFDSGVRSASDVFKALALGAKFVFVGRLWVWGLSIMGEHGVRHVMKSLLAEFDILMNVAGFQALGQIDGSLLESYEKSYQLLPEKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCN5</accession>
    <name>A0A6A6PCN5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_332661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCN5"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000495">
        <property type="entry name" value="Putative G-patch DNA repair protein (Drt111)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="372"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="438"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="57096" checksum="B164E8C1FA68A6B9" modified="2020-06-17" version="1">MADSNSPPAPGGGGGSGLSGLYASLLNPDPSAPGTISRAPVLNKLAAGGNADADAEAKNAQSTAQRFAPRFTQQPKRPAPAVGTKAKPKMAFPKTLGSSSVGTARTDQPSLSPAADGGASSLGQPQQGARAPTTTRLEDWAGDDDDVNDFYGADEKRQRGGRKKRKKRHDKAAAEVVVNWDDNYDSGQPTDYLKFPRSDEKYAEQGDWNETLHVKSRAHRTQSTGLKPSRMAAIAPPPELMGTPANDIESVQFTVSSPPPPPTDVPDDPTGEDAYARRMRMSMNPRPPPEDEFAPPPPPSPPSESLPMSSAVPSSTPAVISRAPVRCNLPAAPTDMPETEEELAEELATDPENLPESGVEGEDQPRSRRPGQSGFAQRLMEKHGWTKGQGLGARGTGIINPLMVKKRKDVEGRAKIVGGQKSKHALAEEEGKFGKMSPVVVLRGMLDGMSIEEMADEGLLQDIGEECSEKYGRVERVKIHFESQAESVPVFVKFTAELSALKAVNALEGRMFGGNTVRARFFDLEAFEKGHYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCS6</accession>
    <name>A0A6A6PCS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_66</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCS6"/>
    <dbReference type="OrthoDB" id="3540210at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="571"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="735"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="769" mass="85344" checksum="5E02D9351A5ECC86" modified="2020-06-17" version="1">MSTLASTSGSAVYTGFWVDRTKDPVEGATITISEDKSTLLVAFLAIYVQTSGAHFWNLCCFLFFQLRSTTKPRDGLHHQQQAVLRNSGTDANAVWLFVETGWRWRHSVRRPFLRTLPWVSSALLHLLAFTAAGLFSSRVTSAHSRVLLDPGTCGPWANPFARGTPTTEENQVERLDFIAHTLRDYSAAAEVADICYNMTEAKEDCNAFGPSDMEWTLVVDDSCPFAPEICATDQTATFDSGFINSHDTLGINAPPEDRVTHRKVMECSTLQRDGYMTDWHQLPNVTLTTTNTLQDRSQEWFLEFYYGRNLDWGLNSTLLYSNLTPTIAPGTFRVQSYLLSAETAYLHDQLMSSFIPIDSLNRTDADVHILFLAQDAMYNQESTDPWFRAEVPESSLVLDRNGYQNMTTWFSKWPVMAMGCTLQHQFCNPNGEDNGLGEGACTPATGLLEVKNYFEDLDLNDRQNTTAHRMLSSVTESSFSNMIQQLGGQWLLANKQGLTTRRPPLPSTQWLTELNHIFGTMLVSLQVQAFNYPRNDQGSAIDRPEYIRATTADENWMCSAQVVRSSSFGSFSVLGIVLILVLGGLFILLNLSLATIVGWWTRRQRRQRGEAAGTDWVSEWDSLEVSALQRLAYQTHGVDLTRHGSVAPVLKSASTLDFGESDAGVSPKAARAPKHSASFWSLGRKKLRTNSDLSKMSDGSATQCGHEGDAQDSKEGALEVAVREAPVSPPPQLSPTPLLSQVPLTPLPEDVSPERKVSDVSSPSRASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD40</accession>
    <name>A0A6A6PD40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_277177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD40"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="560" mass="62736" checksum="96664743C463761E" modified="2020-06-17" version="1">MAGPGGGPSRRSHTKSRKGCKTCKKRHIRCDETFPQCRNCTKHQVRCDYMDSPTAGSPDSPRGLQQANLLWSADIERQIDVWRQTGEFPFPELGVYPQPQWHAYSKADLRLIHHLSSISNEMARNRTTKLTIWTENFPRFLSTATSHPFVMHSILSFSANHLAWVTQSAETRNLAYQHGGVALKGLNEAIGNFSKANSDAILASSLLMSWQATDWRGWASLMTGIRTVLNFMQPWKHESIFADYVSELGLGSNVAFANPSGFQITEDARREHLSVLSQIRSSLSHLQPYLSRHDQESKWVEQLKTYMERLRSANAPRSPEEQFSQLYSFRKWLFWVPISLLSSRKGDMMALVVLAYFYATALALEPIFADVGAPFCSNMALAPLEEIIRIINSFQTSSSYDQVTHAALMMMDFPRDTASSYRTQRQWSQQQTEDVPAIQGSPYGLDSLNFDLESQMSDYSYGQSLSPAFAPSPLQLVPPVVANGLVTGQKSPYLEVPQPTLESHQGYAAATSSFSTPLSSPAPLQSPAVIHPYTFKQESDAYYPNVPFGYGGFVAPTIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD77</accession>
    <name>A0A6A6PD77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_312445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD77"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="296" mass="33542" checksum="BA3C06B8631EB1AC" modified="2020-06-17" version="1">MNTPSEMIGQSGRAYVVERVLQDEGLPFGRVLFARHARRNFSKILVLKGILRGNFRSRLNIYERVGSSPFLRGLLDTIPEQSMILKDALRGLTALHERNIVHNDVKANNILIDVKEEKEKEDEMEFERIQLADLEDAAHIPPGSILEGAQLGNWMWRSPEAHAQGPVGKASDIFSFGVVCIYAVTKRVIFAVDNEELAPGEELLAAVLERQISCFADEDGLHGLLRHLGEKNPWCQVFEVLESGFNKENPRKPFSLWRVEHFDEDFKDLISGLTNFDPAKRITGQEALAHRWFEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDC7</accession>
    <name>A0A6A6PDC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translationally-controlled tumor protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_330195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TCTP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDC7"/>
    <dbReference type="OrthoDB" id="10248936at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.10:FF:000002">
        <property type="entry name" value="Translationally-controlled tumor protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034737">
        <property type="entry name" value="TCTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018103">
        <property type="entry name" value="Translation_control_tumour_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018105">
        <property type="entry name" value="Translational_control_tumour_p"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991">
        <property type="entry name" value="TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991:SF0">
        <property type="entry name" value="TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00838">
        <property type="entry name" value="TCTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01653">
        <property type="entry name" value="TCTPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01002">
        <property type="entry name" value="TCTP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51797">
        <property type="entry name" value="TCTP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TCTP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="18931" checksum="C00308165719BCB7" modified="2020-06-17" version="1">MIIYKDIITGDEIISDSYGLKEIDGAVYEADCKKITIGGENIDIGANPSAEEADEGVDESAQTVIDVVHSFRLNETSFDKKSYLQHLKGYMKNVKQKMQERGASADEVAEFEKVAQAYAKKIVANFKDYEFLIGESMDPDGMVILLNYREDGMTPFVTVWKHGLTEMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDN4</accession>
    <name>A0A6A6PDN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">BDY21DRAFT_312948</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDN4"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.342.10:FF:000009">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="175"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="241"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="539"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="1008"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAF2462071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1106" mass="125093" checksum="CE76435ABD840B71" modified="2020-06-17" version="1">MATAAQQQQHAPAKRILAESTRRNIAPSPAKKRKLVNDGPPGGGARGAAGAAPPGSSQPKSQFEEEVLEKLSQGMTGLKAQNAEKDQRWARPSLPPDAVDPSKQSLCFQQIDAEEGVLVGAGTAVRLFGVSEAGHSVLLHVTGFLHYLYVAAPVSFQPSDCGPFEAYLESQLGHYQPVIHSVQMVMRENLYGFQGNQKSPFLKITVNDPKQMREVRSTIEEKRANYKGLWHITDPEEKITTYDDIQYVLRFMIDCKIPGMSWVEVPPAKYNILPAPQRQSTCQIEASVHYRDLIAHPAEGEWVKMAPLRILSFDIECAGRKGVFPSPEIDPVIQIANVVTRYGEEKPFVRNVFCMDTCSLIVNTQILSFDEEEKMFMAWRDFLEEVDPDVIIGYNIANFDFTYLLERAKHLRINKFPYWTRLKNLRSEARKSKFSSKQMGNRDTKTTNTNGRLQLDLLQLVQREYQLRSYTLNSVCAHFLNEQKEDVHHTMITELHNGDANSRRRLAVYCLKDAYLPQRLMDKLMCLINYTEMARVTGVPFNYLLARGQQIKFVSQLFRKALEQQLVIPNLTEKGSGEQYEGATVIEPTRGYYDVPIATLDFASLYPSIMQAHNLCYTTLLDKTIAEKLGLKEGEDYIVTPNRDMFCTAKVRKGLLSQILEELIGARKRAKKELAVEKDPFKKAVLNGRQLALKISANSVYGLTGATTGKLPCLPIASSTTSYGRQMIERTKEEVERKYTIANGYTHDAQVIYGDTDSVMVKFGPGELTKAMELGQEAAEYVSAKFIKPIKLEFEKVYFPYLLINKKRYAGLYWTNSNKFDKMDSKGIETVRRDNCRLVQTVIETSLRMLLIDRDVNGAQEYVKETISDLLQNKIDMSNLVITKALAKSDYDAKQAHVELAKRMKKRDKDSAPALGDRVAYVIVKGAGDAKNYERSEDPMYVLEHNIPVDTKYYLDNQLAKPLSRIFEPILGEKRAASLLTGEHTRAIAVAAPTMGRLMRFATRTATCMGCKKPLTGAEERDGAVCADDRPRLAELYHKQLARAADLEVRFARLWTQCQRCQGSVHCEVICSSRDCPIFYMRMKAKKDVEDAGRELERFDRDAALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDQ4</accession>
    <name>A0A6A6PDQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDQ4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025423816" evidence="1">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="260" mass="27903" checksum="EE0559A71037F053" modified="2020-06-17" version="1">MLFSKATALALLATIGLSVASPINDVSLKPRQHEPVPARPGVLPAVRRDADVNGDLALKERRQKQRRDLAKRTFDVALQAVDVTQVTQVTDITVVQQVQQVVVQQQVFNQRFDQLRIDWFSANFVQIAVVVQVVQVVQVVQVIELNLVAVQQLFVQSAITANIGAVETDTVQVTDVHTLTVTQGGEPEATNLVVAAEAEETAIAEETAIAAETAVASDASAYPEPSTVVVHPATVMEAQPTWSVVMADPAAAMAGVRRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDS6</accession>
    <name>A0A6A6PDS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_7965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDS6"/>
    <dbReference type="OrthoDB" id="10265389at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="248" mass="28433" checksum="D394B791AF4220C4" modified="2020-06-17" version="1">MVLDEWSKCMSYDYESFNVAPFVAILEDEGIYDRTSAPKASSTSPVPEEMHKDVSATSELLTPPNSSRSQLTDESWDGDQDPHETLKALGPWPMCWSHEIDPEFARAHYKAERAVERAAEKRREALRKLAKLPLELPSLERINALLADGDALRAECPKGVNITPVELAREFVQHCLHLLEDEIRMYGREVFVRAVRLLVLFVRNLVVKALVDPEELFFEIMELTTRYIWVKEVRDLRSFMEGGEEVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF85</accession>
    <name>A0A6A6PF85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_6112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF85"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="33278" checksum="912F13988EA3B699" modified="2020-06-17" version="1">MPSVPGPPGPACGVFHGLLQAAPAAQRLAASTESTAFVFFFHGEKIVERGAATRTRHSLPAQCHNSVGLEVSLVHRQKVHEQPSGLEAVTSRRRVLGSPFRSAPNGRPPALALGGAHMHIHTRLGRSAAHAVRARPSRASDLDVSSLESRARTHTHETYIHPTPTLPSGPDHLLSAPFTRAGPFSSSSNVFARLGREREREREKGAPWESERPRSNLACSSVPRTLARFFPGARAHTHGPGPAHASQRARARQGEAGKATRRARPTRRLQSPFFCPPRLRSAPTHRFARNSAIWKGPGADGTGGPGQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKZ7</accession>
    <name>A0A6A6NKZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_173010</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKZ7"/>
    <dbReference type="OrthoDB" id="3695248at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025470862" description="CFEM domain-containing protein" evidence="12">
        <location>
            <begin position="20"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="13">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="185"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="185"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2452375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="26949" checksum="B7F011EC93B7FADF" modified="2020-06-17" version="1">MLLNLSLCLTLLSLRVVTAHNTPQCWSDCVDSIHEYNCLTWDISCICRESDVEPLSALLACARRECASDEEVNISLLALNAACALLGDAIPSSVIRSAEVAATATRTSTRRSTGGHSTRTDDDGDRTSSDWADIVTGSLHTTVTRTDTDENGSTVMIVIPITIGPSGVVQGSPSTVAATTSIRTTAASTDSPAAAPASSSVASEPTATAAPSSSATITDSSSSDADADSESGEGSPFDNGGSAGLPAIYCLAIGMGLLLGINMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLV3</accession>
    <name>A0A6A6NLV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Citrate lyase-like protein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_294231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLV3"/>
    <dbReference type="OrthoDB" id="1773at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000023">
        <property type="entry name" value="CitE, Citrate lyase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308:SF0">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308">
        <property type="entry name" value="LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="34544" checksum="5DCF226BC91DA95D" modified="2020-06-17" version="1">MASPIIRRALLYVPGSSPKMLSKSRGLVADNVTYDLEDSVTPGKKAEARVALREQLSQPRAAGVREQAVRINSVDSGLALDDLTEVLKAPHLDAVVVPKVNSPSDLHFITDVIRHTLPSRHPSSPATSSSATARQPPLRILALIESALAVTSLPAICASSPYLSGLIFAAEDFALDLSLTRTPSLTEFLYARSAIATAARAANLASTIDLVCTSYRGEAGERALRDECADGKRLGFNGKQCIHPSQVGIVQEMFGPGEGEVEWAVRVVVADRKADRAGKGAWTLDGKMIDKPVVGKAKAVVERATVCGVNVEGVMEKWKGQEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMP1</accession>
    <name>A0A6A6NMP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_158938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMP1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="16717" checksum="5BB978C3AFF50E28" modified="2020-06-17" version="1">MGWRECASCVVVLDKTVGGLFPGRDERGRRKPLLAGVLVRPAQAPSISPIGPRKHKQTNKQKVKQKNTMAGPEQGLRAGVSPSQRSRYVRRCAGAESWSYCRYLSAAVVAAAAAGTTTGPKQPRLELGLRLPSGAPARRTQRRKRGFQSGNRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMT2</accession>
    <name>A0A6A6NMT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMT2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="426" mass="47929" checksum="3C9705629D8D5D68" modified="2020-06-17" version="1">MSAAILSAPTLPPSMPTFRGHDWTKKVFHNPYAYDSGLCICLGDSRSEVERSLPRNESMADSRGTDDRESEMPYQATSSSEDCGTQRGPKDSAEVVSNTRTAIEIFDDENDDENDDENDVNDGNDEKNENDTGAVTNPPFHQLLDRDDDTRLPIALVEEIVDHKNVKLLWAYHPSEAVTPRRMRFGRKEILLSQGHQQTLSTENLIDVAEVEENCDASDDCWYWRRRYDEYRRQLRGKRKHLSGIKDDQNGDATATDPSNDSTEAMSSQGREIFFATAATQFEDYRDATSSAEVPLLSGVLSNSASGPTVGRKQGKNSIPDSLDEIELPIRIHQISFVDAYGGSLYYEWKFGRGEWRNPHVGRATCEMIMELFDQVDPSSVEITMVHSGISKWKWNAMSRHYETDGAGPMSWDAVRKLLSAPEPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMY5</accession>
    <name>A0A6A6NMY5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_147021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMY5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025512776" evidence="2">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="8861" checksum="0855699869DD8A0B" modified="2020-06-17" version="1">MPANKLDTTLGFCIFSHIVALATADNSAEQILSLQFPKGKYLLKVPSGKEVRDRGCFGDQEPRSARMARPRNGTRTVVGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN06</accession>
    <name>A0A6A6NN06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA N(6)-methyladenine demethylase</fullName>
            <ecNumber evidence="2">1.14.11.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_357700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N(6)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:49520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12414"/>
            <dbReference type="Rhea" id="RHEA-COMP:12417"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="1.14.11.53"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:49521"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.53" evidence="2"/>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN06"/>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990931">
        <property type="term" value="F:mRNA N6-methyladenosine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.590:FF:000014">
        <property type="entry name" value="Oxidoreductase, 2OG-Fe(II) oxygenase family family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557:SF2">
        <property type="entry name" value="NUCLEIC ACID DIOXYGENASE ALKBH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="11">
        <location>
            <begin position="283"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="144"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604574-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="422" mass="45658" checksum="D486028CE1E92C79" modified="2020-06-17" version="1">MGGPGLDPHRPPPDRIRSIWKRYRHMQASTLDADPDVLDFSRGLSPGQRGQVREFPFYAPAELERIFARFADGRDPAPGSSSSPSAMPKEPPSMAYEHRNLQGLVIIPSLLPPHVQLALLSRLFHRDLSNSRHMTNVHLHHHVVYPPSTSHSHRKSPASTPPSANPANGSAPTQVSPSPSATPTPPSPSFFSLPVTTTTPFPPLNPSTHRPLPLSSFLSRKLRWLTLGAQYDWTAKSYPAPTASTSDADNSGDGSPSTAAFDASPAFPADIAALLRGLFPQTEPQAAIVNVYAPGDVLGAHRDVSEESARGLVSVSVGCDGVFVIGHAGEGGDDRRENEKEEEKEDVVVVRLRSGDVVYMDGRARFAWHGVPAVLAGTCPAKLREWPAGGGGRVDGEDEAFEAWRGWMAGKRVNLNVRQMWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNF4</accession>
    <name>A0A6A6NNF4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_367445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNF4"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000006">
        <property type="entry name" value="DUF21 and CBS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF97">
        <property type="entry name" value="METAL TRANSPORTER CNNM-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="61"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="266"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="421"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="701"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="661"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="795"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="821"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="858" mass="90416" checksum="7B5C461857FC529B" modified="2020-06-17" version="1">MSSVGAPGMGRQALTTGWASSFKLSVHALIIAFSFRHAAAAPAGYLSPSSFGPLAEGESAGSPGFWAYLGTAIALVLLGGAFAGLTIALMGQDEIYLQVLADSGEGSERKDAKKVLKLLKRGKHWVLVTLLLSNVITNETLPLVLDRSLGGGVAAAVSSTVLIVIFGEIVPQSVCVRFGLPIGAWMSPFVFALMVVMAPVAWPTAKLLDWLLGDDHGTVYKKAGLKTLVTLHKTLGQHPHERLNQDEVTIITAVLDLKAKPVGSIMTPMADVFTLDADTVLDEKMVSKLLDTGYSRVPIHAPDNKMNFIGMLLVKMLIAYDPEDKLRVRDFALATLPETRPETSCLDIINFFQEGKSHMILVSDYPGEPFGAIGVVTLEDVIEELIGEEIVDESDVFVDVHKAVRRLQPAPRFRMPKGVITKTAPTAHLPPHPDGRSAKSTEGQIGPKDAVPRKGSPLGTMPAGVHADLGKSPKTTTLMMRRRSSGNGTVVVDPAAHPVPIRSDDPNVMANLRSLGPSNVATRPKGTRITSVKIKPGVGSGTLAGQSSPIAPKQVDDINRPKPAGRSASVAAPTAEETTPLRPSSSRTDISAPLSGSVGEGVLRNAGRDASDAAQTVQQGYGTMGGASGEASASSWRKPARPLGTIKTANGSPVAEREGGDEQEGDGDDANETDGLLGSNRIYRDSSGGLHVEETASGKIIISSPHPGTPLGDQNSPPRLESTHSSLGGKYAVHSDSSGSDTALRPPSQPWTRGAHARSGSIHESSVELAGGVRKLVLEAGDTESDEGGSAGSEEAEHAQHDAEETREGIVGKIKGLTGKERKKAKKKERRKRGRKHKNTGPKDEDTESGELAPLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNM0</accession>
    <name>A0A6A6NNM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNM0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="64" mass="7359" checksum="B85F578030F5E729" modified="2020-06-17" version="1">MSPEYHLHYNRASHKTACLQLHQKSTFPSNHRPSPLPTSPNPRLTNSTLAPLPQTPFLHPRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNR3</accession>
    <name>A0A6A6NNR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_144962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNR3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="226" mass="25171" checksum="479CD55171A5F9E2" modified="2020-06-17" version="1">MVRPGTQVPSPTDRRLDDCSVPWQPARPLARLFPANAYTHMHAHMHTHTYTHTHTATLTSLCEPPTVLPRVHFPPSEHIPGAVLPTHMRVPARSLPPPCGYEPQPERDGREARGREKMDKKSLAHKQNSGFPFGRRKECTRWLRTLPPAQDRALIGLTSLLPALSRGTMERLGNIYALFSFSPSPDVALESCISKRTSPPGPPLCPLQFDVHSFRRSGPATWFAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPC4</accession>
    <name>A0A6A6NPC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras small GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_120607</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPC4"/>
    <dbReference type="OrthoDB" id="6585768at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090068">
        <property type="term" value="P:positive regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04128">
        <property type="entry name" value="Spg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000330">
        <property type="entry name" value="Septum-promoting GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017231">
        <property type="entry name" value="Small_GTPase_Tem1/Spg1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037527">
        <property type="entry name" value="Small_GTPase_Tem1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21803" checksum="FB33566A8B50068F" modified="2020-06-17" version="1">MVGDAQIGKTSLMVKYVEGAWDEDYIQTLGLPARMPGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDSFVNFPMHEQEEISNQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLSKAFDLRCTIPEIQEIGEPLLIYQSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ87</accession>
    <name>A0A6A6NQ87_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF788 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_366623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ87"/>
    <dbReference type="OrthoDB" id="10012212at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19999" checksum="6C11D1761291FAC6" modified="2020-06-17" version="1">MAQKAAKSLAARNTATLNRTHLITLAVHTFFLLLRALLFRSSFSRTSLLLYLGLSSPALATEFWFERIARPVRDSTRGGELVQPGEDLEAKGLTEWMWDVIYWTYGCVVVSALFGDYGWWLWGIVPLYSIWLAYTTFVSARSGMAGMMGGGDDAAAQAGGASKRQQKMERRGGQKMQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQH4</accession>
    <name>A0A6A6NQH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_292160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQH4"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04469">
        <property type="entry name" value="S1_Hex1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037318">
        <property type="entry name" value="Hex1_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A-like N-terminal" evidence="3">
        <location>
            <begin position="285"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="2">
        <location>
            <begin position="358"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="431" mass="49478" checksum="23CFD80551747CFA" modified="2020-06-17" version="1" fragment="single">LDFEARVPIPFSVFPSSYRSDAVTAESTHVKVEAEADLPEQASRVGREGHETRYSAAFSPSRKDQGHRRYEEEEEVRVYEQDRIRRPGRTEEDIRVSYREEQPRDRVSYVESRDRFDREYPTVHGPATHYAESQVDRTEREFRERTSPIVAGATVSEGRFGGQEYAAEYQPRYGQRAQEFETRTSRGPAATEVRVEETRTTVDPPKKRKFDMGYYDEDGNYHSFRRGLHRAADRILHPIHGPHHHKHHHSDDREEVVIKETVSAPSVPRAPDRAPTFDVRAMPPNTITIPCHHIRIGDLVILQGRPCQVIRITTSSQTGQHRYLGVDLFTKQLHEESSFISHPSPSVVVQNMLGPVFKQYRVLDVREDGRVVCMTETGDIKQSIPVLDQSNLFDRLTEAFDNGRGSIRVLVLSDEGRELAVDYKIVHGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR97</accession>
    <name>A0A6A6NR97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_292121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR97"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="34572" checksum="0C5A53D21BF6A676" modified="2020-06-17" version="1">MSGFGFHTTSEEVCNKFSSEIKGKTFLITGCSPSGLGAEMARTLALHSPGLLILAGRRLEALHETAAEVKQSDPSVTVRLLKLDLASLAQVREAAAEVLRYPEPIHCLINNAGLSGIPYKLSEDGIELLFAINHVGHFLFTNLIMPRILTAGPGARVVNLSSVGHLGSPIRFDDINFKKGDYTWVKAYGQSKTANILFSLSLADKLKDKEITAFSLHPGAIRTNIWRHFTTDYMFKQGWVDEEGNSTEGVIHWKNMSEGAATSLVAALDPELSRHSGAYLDDCQICSAAPYAMDKDNAEKLWKLTEELVGQKFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRA7</accession>
    <name>A0A6A6NRA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_387669</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRA7"/>
    <dbReference type="OrthoDB" id="10253125at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000002">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000004">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="78"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="27856" checksum="D2ECC5C53983F01E" modified="2020-06-17" version="1">MAEAPRGGGFGARGDRGRGRGRGRGRRGGGKSEEKEWQPVTKLGRLVKAGKIKSMEEIYLHSLPIKEFQIVDFFLPKLKDEVMKIKPVQKQTRAGQRTRFKAIVVIGDSEGHIGLGIKTSKEVATAIRAAIIIAKLSVMPIRRGYWGTNLGEPHSLPTKESGKCGSVTVKLIPAPRGTGLVASPAVKRLLQLAGVQDVYTASSGSTKTLENTLKATFVAVTNSYGFLTPNLWKETKLNRSPLEEYSDVLREGKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRK9</accession>
    <name>A0A6A6NRK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_111334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRK9"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF152">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="514" mass="58212" checksum="6742999F41AF3B66" modified="2020-06-17" version="1">MSSSILSAAVQQLAPCAWYIVAGALLAFVATRVVYRRFFHPLAKIPGPFLASVTTLYQAAYNAQYYKKIEQLHQIYGPVVRINPNEVHLSDPENYDKIYYMGTRFGKAPEFYGSFCIPHATFSTPSNEVHKGRRAALNPMFSRKMVLELESIVQDKADKLCKLMAKGLRETKPVDLHHAFRCVSVDVISDYAFDKSYNLMDQPDLGAHFFVMARGIGPAMYTFQSLRWLQPLALKIPPWLAPKLSKPLGTVFALQMEGVNQIEDVRSRMEAGKLDTEARPTIFTELLKPENYPGRPVPSTMELKDECYSILVAAADTTGNAMTTAAYHIMANRDIYDKLRAELFSAFPDPHATLDFLTLERLPYLTGVIKEALRLSFGVIGRLPRVTPEPGVHFNGYYIPPGTTIGMSSWLMHRNPEVFPDPMKFSPERWLDPADFRRLEKHIVPFGRGSRQCVGMPLAYCELYVTLGTFFHRFAGLEVFKTTPHDLEYEDFFSSYHLAGRNWLRAVGPVLEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRR2</accession>
    <name>A0A6A6NRR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_326144</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRR2"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF5">
        <property type="entry name" value="O-METHYLTRANSFERASE ASQN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="222"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="432" mass="47136" checksum="1FC31D66C3F1BE57" modified="2020-06-17" version="1">MVSRDTLSLVDLAARIAADAKKLQQRLETIGHPQPSFAPDTPAIYPDDAEAQAARMKLITAALDLYGLATGPRDFIVWDAFLSKHDTMTFDVLNEFNFWHAVPIDNSASYAEIAQRTGLEEAVVRAVLRLSMSRRVFAEGQDGHIVHTAVSAAMTRDRLLQSWIGHHLQDVAPGCVQFARHLRANGGRSSTDPAKSAVAETLGGRALFDVLEAEGDGWRMRRFAEAMASMKSSSHDLEHVHAGFDWGGLGKGATVVDVGGSGGHVSASLAAAHPGLRFVVQDLPSVEAEYAAAVPEELRDRVKFQVHDFFAEQPERGATVYLLRHILHDWPDSQAVAVLRRLVAAMRPGEGGSRIVIMDVVMAGHGTVPLPLERVQSCMDLQMRVALCAHERTRAQWEELLKESDSRLKLKGLVVPPGCAGAVMEVVLEDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRW8</accession>
    <name>A0A6A6NRW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_291196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRW8"/>
    <dbReference type="OrthoDB" id="5102167at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="72" mass="8197" checksum="052CBEB98EDD3981" modified="2020-06-17" version="1" fragment="single">GEAVNEIVRLTNSVLKMVYNVQTQGYKPFEFSRVAIGGFVEHADVPVQRMKWTSDCRSRFHNGKETQPVTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS67</accession>
    <name>A0A6A6NS67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_352109</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="12">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NAC-beta family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS67"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000003">
        <property type="entry name" value="Nascent polypeptide-associated complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="14">
        <location>
            <begin position="33"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="117"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2454556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17390" checksum="AD9AD5612DAB51EF" modified="2020-06-17" version="1">MDQAKLARMQQQVRIGGKGTPRRKVKKVHKSSGTDDKKLQASLKKLNVQPIQAIEEVNMFKSDGNVIHFSAPKVHASVPANTFAIYGNGEDKELTELVPGILNQLGPDSLASLRKLAESYQSMQKEKGDDKKDDDDDDDIPDLVEGGNFEGKKEADVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSC9</accession>
    <name>A0A6A6NSC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_423899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSC9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="346" mass="39163" checksum="DAEA38CC40B9D4E7" modified="2020-06-17" version="1">MLKAENDRLSARLIQLNEVIEDNHELMARNSNALRVAQEEAKKHAATLKEKDWQVTDAQEALRRARLDLKARADRVDQIMGQLLVAKDDRTMLRKQLEELSSLYNESFTEGKKMEQDMAELRLEYEIVEKRADEASQALGVAKHDAEVKAAQVAEKLRMARHETRVQSNARLNAERKQADTASALSDAAKAQHDTERQLANTADTLDQALRDAEELKANSAKALNKVRLETKRQHDVDAVALKEKSEQLADAKAEAALNMKALRETQKVLEEFRQELGTLHRKHDEIKRKTKRKETRTQNLRELADRLGSEKATLEIQALASNCALCVGIIALGLYYLGLYYISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSP1</accession>
    <name>A0A6A6NSP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_400248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSP1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="296" mass="31778" checksum="D1FBDF7B15805227" modified="2020-06-17" version="1">MYLADSFNAAGTAVRKSRFAAPLPPVLSSHGGTVCSAQSVLRILRTARNTPFLLVAQSAKSIQSLPSRYTANPPLPIHPRTPHLSANPLAPPSAPAPQRLSTRVLSRTARPTRTDPSVHARIHTRSRTRSLFSPYVCTPNSHRLSPFPALSGARLSVPRRRLVRVYVVSGSARPLGPLYADQGPRNGMAQAKTPSGSPVVACQRGGGAQGHRYIRVGGCGWWRDGRPAPPGSVPGQLELTTGWDAAHSHARSSPWAQGQARWTPHVRAGAIARDESVDSRHEVALRTSAAKGKFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT13</accession>
    <name>A0A6A6NT13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT13"/>
    <dbReference type="OrthoDB" id="2565191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022793">
        <property type="entry name" value="Rrn10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28054">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28054:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="297" mass="32878" checksum="E4C695F675BFB371" modified="2020-06-17" version="1">MRDISVTGSRGRDERISHRSEKKQQKGLRKAPLQHGVGESIERRKRRVATLYDAVAGRVGTNGFLKPLPLLSAHRDTISRSRVPIPPDEVLFKRKHAPIRYQEDDFYWADSQLDPQRDLLPDSHLVKAVHAYASDFANAITLADRAEPAIHGTGSRGVPGRSRRQFRSLDETALLAMSILLEETVKERLGKTGDLALTEGSNRKAASSVWDDYTLLGCMIGEGGSISPTQNDRLGLVKRKRTKSHLKPASVATEPLTSSSESPAPSNLSVIDTDIVHKRRKPKRRRVGSTPKSSITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTD7</accession>
    <name>A0A6A6NTD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysine decarboxylase-like protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTD7"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000018">
        <property type="entry name" value="Lysine decarboxylase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="25424" checksum="D6F177146B0C898A" modified="2020-06-17" version="1">MPEPESSTAPSSSAVSKGPVVCVFCGARPGNAPAHMAAARALAHAFHAHGIRLVYGGGTVGIMGELAQTLVSLSGPESVHGIIPFALIKHEAGHPAESTAAPISASSDPTDPSASPSTLSPVFGRTTVVKDMHTRKRTMASEVMKGGPGGGFVALSGGYGTLEELMEVTTWNQLGIHGRPVVLFNVDGYWDGLWQWVEKAVEQGFVSEGSKGIMVQASDAEGVVKALIDYKVAEGRFGLDWGTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTU9</accession>
    <name>A0A6A6NTU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase, V0 complex, subunit E1/e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_351510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTU9"/>
    <dbReference type="OrthoDB" id="1508846at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="9033" checksum="FF64996094BA91C9" modified="2020-06-17" version="1">MANGWSVWIGLLVIAVFSVVSWFAAPKGENQTVWRSSLILAACACYLLWLITFLAQWHPLIVPRRSDLRPEIINHERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUB7</accession>
    <name>A0A6A6NUB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pro-apoptotic serine protease NMA111</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pro-apoptotic serine protease nma111</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_324736</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclear serine protease which mediates apoptosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUB7"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="264"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="843"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="982"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2455375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1009" mass="110449" checksum="0171608C954CC832" modified="2020-06-17" version="1">MDVDYDSAGGGVEDGDSVASGESMAHVISAGDSAEWQATIEKVVRNVVSIHFCQTHSFDTDPAVSSEATGFVVDSEKGYILTNRHVVGAGPFWGYCIFDNHEECDVYPVYRDPVHDFGILRFNPKEIRWMPLGELKLRPDLARVGSEIRVVGNDAGEKLSILSGVISRLDRNAPEYGEGYSDFNTNYIQAAAAASGGSSGSPVVNIDGHAVALQAGGRSDGAATDYFLPLDRPLRALERIQKGEPVPRGTIQTQWLLKPFDECRRLGLTSNWEDLVRKSFPKETGMLVAEVVLPKGPADKKIEEGDILIKVNDELLTQFVKLDDILDSSVGNKIKLLVQRGGQDLEVELQVGDLHAITPDRFVSVCGASFHDLSYQQARLYSIPLSGNGVFVCESAGSFRFEGSESGWLVQTVDNKPTGSLEEFIEVMKGIPDRAQVVVTCKHLRDLHSLNTTISHIDRHWSRKMRLAVRNDETGLWDFSDIADPIPPVPPVPRKANFVRMDSAKYPKAVDIVRSFVRVSVDLPIKLDGFPRAKKIGFGLVIDADKGLVIISRAHVPYDLCDIRLTFADSIIVEGKVVFMHPTQNYVVVKYDPSLVKAPVKSAKLSTRRIEQGQDTIFFAYNQNLRPIVAKTTVTDVTTVAIPASASTPRYRAINIECVTVDTGLASHCGSGVLVNPDTGEVESIWMTFLGERSHSGKDIDYHLGLPAPGFIPIIDEIRRGETPALRILAVEIQPVGMAQVRIMGVAEDVIERIEREDPERHQVFMVRKVDSGQAVGGLAEGDIILTLDGKLITRAHHMDAVLHAASLGKPPGEPVTVAAVIVRHRQQMRIEIPTVPTADLETGRALVFAGAVLHAPHHAVRQQIARLHSGVYISARTRGSPAYAYGLAPTNFITHVNGAPTPDLPAFVAQVKRVPDNRYFRLRVVTFDNVPWVATVKKCEHYFPTAEFVKVGREGAGEGTDGEEEVVDEVDRRVGWKRIVHESEEGGAGGDDVLDNKAADVGDGVMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUP1</accession>
    <name>A0A6A6NUP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_349522</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF7708" evidence="3">
        <location>
            <begin position="84"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="298"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1021"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1055"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1087"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1217"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1227"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1240"/>
            <end position="1251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1573" mass="176473" checksum="7622756C6085A468" modified="2020-06-17" version="1">MAARSPSSPSTPSTSTPFRDAIDEFIQSYPKKKKLPQFLASYARGAPPSIRPEDVQSSIEAVEHVFSQKKSTRFVRATLDPIVVVLKDYTAVINSMSQADPMPTAIVWGCVKAAVDCSSRFVDLYAKIESHLKSLSELLRRFKDYEELFGHSSSMRALLKSSYGHVIRFWVRVEEECKHSIALSLAKAVVSFSTRKLDDCLEKLKADVDDVNRLVPIVQERLQKGERENGAEERRKAGIARDELFAFIKEQRAEQKQREADRRETHRRTIREWIRGHAPVNESNFRHHREKSSALKPGTCEWLAEEQNFQAWFDSQSSSQKLWLKAAPGVGKSVLCAFAIQRTKDLMPESGVAFQYFSFDEQLSGTLFCRNMAEQLFDSFCNQRIDLPESFVTHVHNNSNSLENLLMLIRLMAEEMTPTYVLLDGLDEETQEGTDIPPVITYLNALADLGTIKLWCSSQDRPHLRLRFSSFDTIHVDEKINSKDISDYISHALSTMHGLEVDQGTKTLVLDDLVQTAGGNFLWAAYMVNDLSKAGNEANVLEQMKKGLPADCDKYYAATVGRIDCTERGLASRILSCIVYAKRPLYLHELCEAMGMCAIKLGENMSSRNRLFKSKVEDLCAPLVEVQRTGDESGREVCCLSHSSVRTFLLKNRDCLQKGCPPNSEICSLRADVLADICFKYLNQPRYERMLKKKDDTFKTATGEDIDGHQLLSYAAKYWDKHLDDVSPTPELCAQVLDFIKSRRFQTCMQVQSLFIEGQFQFWASVQRPHLGPQLRRTFPWWLTDKDQGCGAPIREQYHAFVGQWGYFLTNYTSSRGPFAGEIDRCLWSSFGPNHMFYKNKSRLKSHLFIDKDEPDRLDCSKMHQTVSPNGTDTMTFKLDNKDLDLNVRCQKWSFSGGHRPRLVKTQTLSVPRKSMLLYTGMLRGNTIGRPPPVTSTPDMRYLRIGPQIFVEEDDKFVPLNGMCAIPPYFEEIASHGHYLAVTTRQKVTERDLFTVGLDDITVDDFGTLFSLLTEIVGENATEPAASSSEQSGSKDNSSDDTVSKDKSTDDDDASSVSSRTSIVSSLSSSSAESIEQTLVDKLPEEVNPDDVDLNEDDGSGFSSSESISARESWSEGSTEPQSDETEDEEQWNDWLSSESGEADLEIKDAEDSDSDFGDDASQASDKVLQKMAKAVDERSEDLDQESDSACSVASTRGEESDVSDDSSESYSPSDSSFDDDDDDESANEHGARIDDILSGKRHGSTRKGSKAKIQIFDTRPGKQSKPLFHLEEPIPGVLFDSPPVFHPSAPLVVWSLGSREILFVDYLHNTYFTRTLHAPTSKSCPVFIRPQFSPCGEYLHFASLEATPDESTLDKTSTSKTALPTLKLLLHVSTHRLSHRKTSRSPPRLLHRITISFGSFSSLSVTRLPLTLTWSPEYLYVSRNDTILHVLRVPLFPRPGDADSRKVWVPRNQVFMPESALKRPVHFFPPPGGSKKTGDLATVIVGAYTRRGPGDDPVLEPMVPKCELSAPIGVYVPVDAELGGWIPLKEANKTAGDEGVKMEEGAKAGRLLGKFEKFDRTEDCDIVPYLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUZ8</accession>
    <name>A0A6A6NUZ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Diphthamide biosynthesis methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_307427</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUZ8"/>
    <dbReference type="OrthoDB" id="2516at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000004">
        <property type="entry name" value="Putative diphthine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="301" mass="32844" checksum="445F171C13CC3F4F" modified="2020-06-17" version="1">MLYIIGLGLADEKDISVKGLEIVKRAERVYLEAYTAILLVEKGQLEAFYGRPVIVATRETVESSSDEILDGADKADVAFLVVGDPFSATTHADLLLRARALSIPTRTLPNASILTAVGATGLSLYTFGQTVSLVFFTPSWRPASFYDRLAENARVGLHSLVLLDIKVREPDLAMLARGKIVYEAPRYMSASVAARQMIEVEEGVGPDDDMGRDAVEGRSEGVCTRGKLAVAVARLGSEGQKVVAGTLEQIASDEVERELGKPLHSLVLVGRRMHEVEMEALMDCAVDKTGWEETWRKEYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV03</accession>
    <name>A0A6A6NV03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="4 11">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_396643</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="4 11"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV03"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="12">
        <location>
            <begin position="56"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="596" mass="65294" checksum="2592527669CF6F4D" modified="2020-06-17" version="1">MQRARHAAVFEAPVVVRAYARPFVVAYRRWPLYVHGRLASTSSSEIQNVAVLGGGITGLTTAYYLTRSYPHAKVTVYEASGRLGGWVRSRRLEIPESDGAQVLFEEGPRTLRPRGNGVAVRGLISQLDLKSEILALPKSAPAAQNRFIYYPDHLVLLPTGATLANSGGTFRTEKLFHDAFPSVLRFAWHMARFTFSWQPPRADDESIGDFITRHVGPGPADHFASAVAHGIWAGDIWQLSMKSLFTRPWALTKRYKNALQAASAMQEGKAGHGPVLREYVGKHLQQGWGDRDFLNELRPASVFYFKGGMETLTKRLEELLRANLKVEIRTGAPVEQISKTEDRSALQVTVKSSESQPQPQSPQAFSRVISTLPALTLSSLCPSPSSSTTSLLPALASIPSATVMTINLYFRTPNLVPPGFGYLLPQTISLEQNPERALGVVFDSFASPGLDDTTRAQHAAFGTKLTVMLGGHWWQGLKGVPNEEEGVDMARGILKRHLGIEEEPAVANARAHRDCIPQYLVGHDDQLVEAGKQLKAEFGNMLRVAGSSYLGVGVADCVLNAWAVVEGLREDDRNGLSEWAGRRDELEVVEGAEGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV40</accession>
    <name>A0A6A6NV40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_68203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV40"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7716" checksum="3B013C30909E0FEA" modified="2020-06-17" version="1">MEFACFAYVGFALFLSIPLQLFEVCPFFFPSMLLFPLWSCMSANSVHVVRTKKNILIQFMLSVKQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW88</accession>
    <name>A0A6A6NW88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_415774</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW88"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18009">
        <property type="entry name" value="DEXHc_HELLS_SMARCA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000015">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044753">
        <property type="entry name" value="HELLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="239"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="669"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="94"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="503"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="744"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="937" mass="104821" checksum="DD9E36F35735B78A" modified="2020-06-17" version="1">MTTSSITADTLSEESTPASSPPPEVSENAVSRSMEQEEEKMRLAREKEDAVRDARLATERQKDIDAGPEVVDNKFKALEYLLSQSKLYSSIMLSQMQRQEEEEEAKDEKGRKRTQKREQQAEQAAEASQRRATRRSAADDAIGDSRSPTEPSTAGIEKTRRGRPKNAQKNGNISSYFKKADVAAKAGGASVSEALEEAATEDVKTSDVGVQNLRSARQPDLVKGGTMRSYQLEGLEWLTSLYENGLNGILADEMGLGKTIQTIAFLAFLREKGTYGPFLIAAPLSTTSNWVAEFRKWTPDIPVVLYHGSKKEREEIRRKQLKKPGTKDFPVVVTSYEICMNDRKFLAGFGWKFIIIDEGHRIKNLNCRLIRELQSYQSANRLLITGTPLQNNLAELWSLLHFLMPTIFDKLESFESWFDFSALKERSGYEQLLNEERKQKLVASLHAILKPFLLRRVKTDVEKLLPRKREYILYAPLTPMQRELYQALLDGTGRQYLEEKAIESLGGTPAPREGEDQSVSAGSKRKTPNSGTETPNKSTKSSRDSTPGTTTRSSTRSSRRMGTRRDYGEISDREFFKQLERARHNEDEDAGSPSNNLGDSANQNRTSILAFAKRQIAAKKLQNPIMQLRLCCDSPYNFWNPFLFSSENGNDGSITPDETLISTSGKMLLLDSLLPELFRKGHKVLIFSQFKTQLDLLEMYAESLRGWRVCRIDGSVPQAERQAQITAFNKPSAAPIPSKLGEGGTKRAKGDSAEKPSNLFLLSTRAGGQGINLAAADTVILFDSDWNPQQDLQAQDRAHRIGQTRNVIVYRLATRGTVEQTLLESAGGKRRLEKLVIRKGGGLREAARSARGKDGEKEREDMELEELQHLLRREDGEKFDVGVNKEGGALLSKKDLDILTDRSEEAYLRAESGQDSGDAFQAVGNIREGELLEGLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX37</accession>
    <name>A0A6A6NX37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_386736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX37"/>
    <dbReference type="OrthoDB" id="442947at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08284">
        <property type="entry name" value="FDH_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF2">
        <property type="entry name" value="DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="30"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="188"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="363" mass="39507" checksum="330E85D2961DA033" modified="2020-06-17" version="1">MPSGTMRAVVFKEPHRVEVEQRPIPQIEDPKDVIVKVEYTALCGSELHVFRGHQPSPVGFIMGHEFTGTVEEAGADVMAFKKGDRIVSPFTTACGECFYCTNGFSSRCESVKLFGSAVLEGAQAQYVRVPSAPSTLFPSPPSAAIPAHLQVLLSDIFPTGYFGARTAFSFLPAPSIRDSTCVLLGCGPVGLCALVCALDYAPRRVVAVDGVQARLDRARELGATETLSLDVGRGKEGRDEVVRKVKEWTAGRGADVVIEVVGLSDALRLGFEVLRPWGGISSIGVHNGEIPWTGNEAYGKNLRIHMGRCPVRSIFPEALEQLKKKQHLLGFMADKIMPLTQAVEGYELFDKMKVQKVIFEAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX96</accession>
    <name>A0A6A6NX96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_347068</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX96"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005366">
        <property type="term" value="F:myo-inositol:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904679">
        <property type="term" value="P:myo-inositol import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000073">
        <property type="entry name" value="MFS myo-inositol transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="62"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="565" mass="60488" checksum="4971CE66D02B0FA8" modified="2020-06-17" version="1">MERQPGIRSPLMESGRSSGDDSGREYGSSLEDGRAPGDVTRLDDDDVEESQLRAPSNFIWALTVVAGVSGLLFGYDTGVISSTLVSIGTDLSSRPLSTLDKSAITSCTSLGALLASPVSGVLTDSLGRKRVLLIADFLFIVGALWQVFTTTVSGMVVGRTIVGLAVGGASFVAPLYISELAPSPFRGRLVTIVSLFITGGQVVAYIVGWLFSETVAGWRWMVGLGALPAVVQCVSLTFMPESPRWLVKSGLKERAAQVLGKVYGSGMQGDNIVRKVLRRVELEVLEEEEATARRRAHADDEVAAKRKWFSGMDSIMETFDELVGVGGNRRALTIACMLQGLQQLCGFNSIMYFSATIFQLVGFSSPTLTSLSIATTNFLFTLVAFSAIDRIGRRRILLYSVPIMIVGLALCSVAFNFLNLDPSSAGSAGLDAPVDDIVASKGVGPWATIILVAMIVYVAGYAIGLGNVPWQQSELFPLPVRSLGSGIATATNWGSNFIIGLTFLPLMEAFAPTGTFAAYTFVCVAGWFAIYRIYPETAGLNLEEVGGLLANGWGVKESMQRRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXV5</accession>
    <name>A0A6A6NXV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_364536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXV5"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25542">
        <property type="entry name" value="zf-CCCH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="34829" checksum="F5A46C275A448D50" modified="2020-06-17" version="1">MAFRLKEDLFQEKHPTAAPKAYVAILMDGDAAMFSDEYLRHGHEGGRVAAQKLHEDVKSMVDKYVDYGILGPEAHNVEVRATFYGDFSTLANACEGAGVVPGANLARQCLAGFGGVEKFTSTNLSDGKNGAVLGCTHEGDYSKRLEELAKSGPERCKVTLIEGLPRTEHIKFLYNQYYSSGFTRIFRSDKIPLPSDIVTNPQRDINVDENRWRLDEPILARPTRGEVSRTKSLKLCFQWYLRGECTDGDCEYAHDVEPTSDHLRVCRYLTRKQVCPRREWCRDPQYFFSKGSTRKARDTVRKWRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY01</accession>
    <name>A0A6A6NY01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bola protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_347037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY01"/>
    <dbReference type="OrthoDB" id="203381at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052275">
        <property type="entry name" value="Mt_Fe-S_assembly_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188:SF1">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="148" mass="16761" checksum="5781DBCFADA5A605" modified="2020-06-17" version="1">MAPSRALSRVIAARSSRFLEVPAPCRLQNHATRSPPYIRFEFDRIPRYALLQWQGIRPYTAQAPTAPEAPEYLTKGELEVFNKLKGELAPQKLEVQDISGGCGSMYAINITSDKFKGLTVIKQHRLVNEVLKDYVKNWHGVQLRTHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY70</accession>
    <name>A0A6A6NY70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY70"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="279" mass="31860" checksum="CE0101D5CE04027F" modified="2020-06-17" version="1">MQKAMGRREKEEQSSCEQNSSANENLENNTTTASTRIPRMLYHNRKLQPSKDLGQRQRSKEKKIRKEKRKQGKDKEYSGHQEKGPRKETQFTQSRGRGTLARQTTAQAIHRSICHRQEYALNRNLNGSHSIDRRYKSTGDPGEPKGERETMCASVQTLNVPKKRSRTYYSFDTPGYGMLPSTLFCGGCRDKHSVWRNARKWVLKCMTKTGASIFRLPARKDSTFSSTSTPTETAHTANLFLLYRTPTNPSHFPTTILFFILYLGAPPFNTTSFLPEGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYG3</accession>
    <name>A0A6A6NYG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor Opi1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_287217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYG3"/>
    <dbReference type="OrthoDB" id="2441642at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013927">
        <property type="entry name" value="TF_Opi1_Ccg-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08618">
        <property type="entry name" value="Opi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="580" mass="62397" checksum="8730D874ABF48BE2" modified="2020-06-17" version="1">MELPPQERPPAYPSSLYHDPESLRLPSVPRHELPAASGSASSVSLPELRSLGLPDALQARAYQDAQSTDTPWMPSASLRNGPLPPASLLASQPDLDMTSPRAESVVSADDRSMRAPSVVSMDDPDVRMAAEALSGLGNPDFIRSPSNRSATLPASPGASASRSVDEISQEPEPLLSLLTSSHPWLGGTINGSLNAYTSTKHYSPRFIQYGAEFVERNIGSPVANTVGSMGRRTGVEGSLRRYLGDRGPSDSGRAESEERESGHGNKRRRVMSSTSDEMDVEKGLRTPSSRGFRSRAESQGSFAETLPAYDENSSPKYEEMNSLVVSEPTCEPSRPGQLRRDHSWSTQLMITTSGLGAALSEGSLRSLKFCLGLLRNGIAHVTNLMRALRMLLDEYEQMTNSDEQEEEDKVDIAQPAEDKPIEGLPRDKEEAARTIAGRIKAISDDILKTMKTVVNSVSRYTGGALPENAGVIVRSQLLSIPSRWRAASASTATASAGASEPVRAAHRMLAFAKEGLDMMTQVTLVVDGTVISAEKWLDSLGRRKKASTGAGAGSFDAKSEKWEDAQDPSGQNGGSMKEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYI1</accession>
    <name>A0A6A6NYI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_379736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYI1"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000075">
        <property type="entry name" value="BZIP transcription factor (MetR)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="200"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="322" mass="35345" checksum="3F524DCD5BDEF74B" modified="2020-06-17" version="1">MAGYHGRRGPNVSQYIASLNVVPSAADMASSTAEEDFFQNDLAQFTNIDFVDLDNLGTPFDSHPNPVPYDPVVEQEARRQNASAFRNLAKQNVDFLNDDFQFSGFGDLPNIGSEQASNHVERDQQQQKQQQQQQQQQPSPLYPLQLNTSATSPTTPTTVASGPSPTAGDKRKLDAPSSKASGGASSPIASEEAARLAAEEDKRRRNTAASARFRIKKKQREQELEQRAKKMTERVGELEGRVKELETENRWLKSLIMEKGEREMGSASGDVRELLKKFTSTGKDLSIVANLSGSSPRDEGRSQVEKKDGVGTVKVESSTAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZE2</accession>
    <name>A0A6A6NZE2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="13">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_372309</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 13">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="13"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZE2"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000097">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF57">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 13" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 12 13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="14">
        <location>
            <begin position="50"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2456862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="57661" checksum="A360FF7BFFAA535B" modified="2020-06-17" version="1">MASLRAGLRAPTSLFARCAQRPIVPVCPTRWRGAAAFSSESQQKALSSSLKEADPAVYDIIEKEKRRQKHFINLIPSENFTSQAVLDALGSVMQNKYSEGYPGARYYGGNEYIDEAERLCQRRALETFGLDESQWGVNVQPLSGSPANLYAYSALLNTHDRIMSLDLPHGGHLSHGYQTPTKKISFISKYFETLPYRLNEATGIIDYPKLEELAMLYRPKLIVAGTSAYSRLIEYKVMRDICDKVGGYLLSDMAHISGLVAARVIPSPFEYSDVVTTTTHKSLRGPRGAMIFYRKGVRRVDKKGVEERYDLEDRINASVFPGHQGGPHNHTITALAVALHQAQSPEFREYQLTVLENAKALASRLGASKESGDGLGYNIVSGGTDNHLVLVDLKDKGVDGARVERVLELVGVASNKNTVPGDKSAMKPGGLRMGTPAMTTRGFQPEDFRRVADVVHRAVLITQNLDKAARKDAEDRGRKNPGSVAAFKEYVGEGENVAEILQLRQEVEDWVGTFSLPWVKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZP8</accession>
    <name>A0A6A6NZP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_286422</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZP8"/>
    <dbReference type="OrthoDB" id="2020073at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.50:FF:000002">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1760:FF:000001">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="14">
        <location>
            <begin position="228"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="161"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="237"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="432"/>
            <end position="435"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="501"/>
            <end position="502"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2457159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="516" mass="57388" checksum="2D065EBA4678010D" modified="2020-06-17" version="1">MASPTIYPEYPPSLNREQETFLLAELKDWTIAHGLAVRPPPSFIPGSQDPSGVLATTAPVTLFPSPFPRDAFDRGLQIQTAYNELYAAVSRDEEWLEEIVKQLLDIDDFVAKLWEIHAKVKADGYVQDLSLGLFRSDYMVHMDPARSNKQPEIKQVEFNTIASSFGGLSSKVSSLHKYLLSTEAYPHSSSQIINAANLPENRSIEGLATGLAKAHQAYGTSKTQRALCVLFVVQSSERNVFDQRLIEYELNSAHKVRTFRLPFSEIQRHTTLDYSRALIYSPPYTPKTSFEVTTIYYRAGYDPSDYPDAEAWSSRLHLERSLAIKCPSILTHLAGCKKVQQVLATPGSPHLSRFLRDEKLASSVLRTFAPIYPLDTSDAGNEAQKFATEVDTASRYVLKPQREGGGNNIYRRAIPAFLEKLPKSHWPAYILMEMIEPPALKNAILRNGEIQQGGVIGELGVYGVCLWRNGDGQTDKGEVLENFQAGYLLRTKGDKSEEGGVAAGFGAMDSCCLIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZP9</accession>
    <name>A0A6A6NZP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZP9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17119" checksum="9CE74EF45CD467C9" modified="2020-06-17" version="1">MTREQKPLARLTDELPRKSKARAGAERRVPGGSAKITRATGPDAEPRQGQASSACRQPTGRKATLANVGSGAGRRSALVLEQIERLKTSEDAVRNYTRLCVRTTVPFGRQAAVERYVPKYAIRRLSGLRTEYQRATGEADDFLYFLAWSAKQTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZX4</accession>
    <name>A0A6A6NZX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL5m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_304363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZX4"/>
    <dbReference type="OrthoDB" id="539541at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="6">
        <location>
            <begin position="187"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="7">
        <location>
            <begin position="244"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="349" mass="39225" checksum="4A787523583BDBAF" modified="2020-06-17" version="1">MALREFCSRMGASLSQDARSLSLRPAWPAQQQCRRLATTAADPDIETEASLNSTGPDEELVKNYDPIARARSRRRQLPSSRYKFRSPRYYRGPLHPHQPPPPTDPSSREFVPGPFSLPRLEQTWESTIAPDLLTLNYQHAPPGMEIVAKARGLRPWVGDNPYFKNRVPRPPRGGMFLPARKPITFRNVPRLREITVHSMVGQAMEDSGYLHVAGMAVQAITNKRAQVHEAKESVQNWGVKKGRPVSVTVDLQGEDMYHFLAKVVEVVFPRIRDFKGIKGTSGDSYGNITFGLTPEEVAMFPEIEVNYDMYPAKMIPGAHVTIKTSAVTDRDARMLLRSMGVPFYGKLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZZ0</accession>
    <name>A0A6A6NZZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_38950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZZ0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="208" mass="22774" checksum="56AE91F9BBB91E38" modified="2020-06-17" version="1">MAQDQGRSSCPMAAPSSSPRGPDWRVRSKAPRVRFVCSSFASRLCDFVRVIRRDVGDLWLGRARAWRPRCQPLSPAAQGNFHRARTRAPDSSPAPGRAFPNGPTLALARLVRTASRAAEIGGEPPVLSASYRAGCRHQRGPWLRCRDAVGPSGRLGGLGAQSGSRWLRLPTRLRLGARVQPFPSQNWRQIALGRLESPGSTRLIEPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P008</accession>
    <name>A0A6A6P008_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_345617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P008"/>
    <dbReference type="OrthoDB" id="3945378at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025428118" evidence="2">
        <location>
            <begin position="30"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="33042" checksum="AF51217397DECA6D" modified="2020-06-17" version="1">MFLSLFHKHHKQGIFTFTLLSFLITPALGSTIVSSGSECTIQGDPDVFGIGVRVSLYLQWGSSIIFLAFSPEQASIPRTTMAATTAALYINTFVAAAHGNLIAIEWLVLFYLTFSLSLLNLPVSRAGLQKHGGTIALMSFLWGIYYVVSPWMFFKGLDIAKEPGCDVKIVIFVPISIYAHGFRTAFKVLSIFDAILLGIANFGLAVYLFVRWIQGWADREVQENIDKPGLRGRILATFQVISGVIAIIFAERTLSVNHVTFPGVAINNSGQLIPFILGLFALVASIFSALKTFSRSHVQGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0B6</accession>
    <name>A0A6A6P0B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_364446</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0B6"/>
    <dbReference type="OrthoDB" id="10266018at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20513">
        <property type="entry name" value="CYCLIN_CCNC_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028758">
        <property type="entry name" value="Cyclin, C/H/G types"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="53"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="155"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="322" mass="36244" checksum="37DF0AE241B5C170" modified="2020-06-17" version="1">MAANYWASSQRLHWTFTKPGLAETRRQMEENEKALHKQYPLPEQRLISIFLMHQVNKLAKRMNYKQQIIATAQVYIRRFYTKVEIRRTNPFLVVTTAFYLACKTEESPQHIRVILAEGRNNWGAEIIPDQSKMGECEFTLISELNSQLIVHHPYRTLYELQQTFSLPNDEFSTAWHIINDHYLTDLPLLYPPHVIAVTAVFLAVVIRPAQNALLPHQHQHHAGNLAGALQSLTSPQSAAAIATQAGVHGPTAGAGASGSAGAAAQGRIVKVVNWLAESRIDMEAVVDATQELISLYEVWDQFNEKACKDAVLRFVQARGLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0F3</accession>
    <name>A0A6A6P0F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glycine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_286222</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0F3"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00858">
        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.230:FF:000002">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="159"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="655" mass="73502" checksum="C52B5E648B27684A" modified="2020-06-17" version="1">MTTTRTGQPFDRAVLESLMRRRLFYTPAFEIYGGVSGLYDYGPPGCGLQANIIDTWRKHFVLEEDMLEVDCTMLTPAEVLKTSGHVDKFADWMCKDPKTGEIFRADHLVEEVLEARLKGDKEARGVKVEDKDEEDAKKKKKKVKDIKAVKLDDAVVQEYEEILAKIDNYNGEELGQLMAKHEIKNPATGGSLSPPMAFNLMFQTSIGPSSNYPGYLRPETAQGQFLTFQKLLEFNQGSMPFASASIGKSFRNEISPRSGLLRVREFLMAEIEHFVDPEGGKKHPRFSEVADVELELLNREVQLAGKTHVERVPIAQAVAKGTVDNETLGYFLARIQLFLERLGVDKTKLRFRQHMLNEMAHYATDCWDAELLTSYGWIECVGCADRSAYDLSVHAKKTGAPLVVREKRAEPLRVEEFAVEIDKKKFGPRFKKDGKSVEAAIEALTQDVREKLSLELKEKGKVTLDVEGVGDGKVEVGGDLLTIEKRTRVEHTREYIPNVIEPSFGIGRILYSLIEHCFWTRPEEEARGVISLPPPIAPTKVLLVPLSNHPDFTPQIKQLSSRLRSLGVSSRVDASGASIGKRYARNDELGTPLGITVDFQSVKDGSVTLRERDCMRQVRASADEVLEAVRRLVEGTESWADVEGRLPRFEGQEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I6</accession>
    <name>A0A6A6P0I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha,alpha-trehalose-phosphate synthase (UDP-forming)</fullName>
            <ecNumber evidence="2">2.4.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose-glucosephosphate glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_285851</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="2.4.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="2"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0I6"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000007">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000035">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012766">
        <property type="entry name" value="Trehalose_OtsA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02400">
        <property type="entry name" value="trehalose_OtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="491"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="621" mass="68843" checksum="CF5A8B9A832080E0" modified="2020-06-17" version="1">MEGRLLLVSNRLPITIKRSDEGKYDFSMSSGGLVSGLSGLSKSVTFQWYGWPGLEVPENEISTLKSRLKEEYNAVPVMLDDELADRHYNGFSNSILWPLFHYHPGEITFDEAAWDAYREANQEFANAIAKDVQDNDLVWVHDYHLMLLPAMLREAIGNTRKNVKLGFFLHTPFPSSEIYRILPVRNEILLGVLHCDLVGFHTYDYARHFLSSCSRILGLSTTPNGVEFQEKIIAVGAFPIGIDPEKFEEGLKKPKVQDRIAALERKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTDHPEWIGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGRFGDIEFMPIHFMHKSVSFDELIALYSVSDVCFVSSTRDGMNLVSYEYIACQENRHGVMILSEFTGAAQSLNGSIIVNPWNTEELADAIHDAVTMSDEQRKTNYLKLSRYVNKYTRHDLILTVPLCSAWWGNSFVSELVRISEQAEKKLKVKRPGGMLLSPSSSASGERATSASPGEILLPTRNVLGSSDSPAGRPLVDNRPGSPAAEGEAETSRSREAGAAGGSADMVAPSPKPPGTPAANVGGAGREFVRGRSSLPGVQDQERHREGYEGGKRVSSQPEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P150</accession>
    <name>A0A6A6P150_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial</fullName>
            <shortName evidence="5">Glu-AdT subunit A</shortName>
            <ecNumber evidence="5">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_414775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="5"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P150"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="539" mass="55973" checksum="D79961C692E3702D" modified="2020-06-17" version="1">MSLLRQAERCVANQVAWKHLNAFISVAAADDVLRQAREADETSSSGRGGAPSSSPLHGRLIALKDNICTTDLPTTCGSAILARYTSPFDATVTTRLRAAGAIVAGKTNMDEFGMGSHSRYSHFGGVAQPASSHSSATSTTAPAHQLPPNPTDAALLSAGGSSGGSALAVSTLQAHAALGTDTGGSVRLPASYVGVLGFKPSYGRVSRWGVVAYANSLDTVGVLAPGARVARDVFAALDAWDPRDPTSLSARTRVRLSAMDATREPRVRRGLRIGVPREYNIAELSPAVRRAWARALERLSAAGHAVRPVSLPTTRLALSAYYVLAPAEASSNLAKYDGVRYGSRAAGPDSGSVARTAGGENADAVGDDGDGDILFARTRAAFFGPEVKRRLVLGAYTLSASAMDNYFVQAQRVRRLVAADFDAVFAVANPLTTAARPPVRSGGAPAADDDAKVDVLVCPTAPTPAPRLADVERLRPVDAYTNDVFTVPASLAGLPAASVPVEGEGEGEDSEGKIGMQVIGQFGDDGLVLDVAEVMEGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1C8</accession>
    <name>A0A6A6P1C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_414836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1C8"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="219" mass="24692" checksum="D83A9CAFDE4A8595" modified="2020-06-17" version="1">MLPFYKIAPTDIHPSHSLAYSLQIEADYKKAAEFIESAAAQGADLAVLPEYHLTSWVPENIEFFELCDVWEEYLEKCRKLAREHGICVLLNVTYFIDNRGDIIENYVKKNLWGPEREHLSRSGRDRHDDLAFPEAFCDLIYEGAKIIIVPTFITVFFTSAGGRSGQGYAVLSQVTVPYIGALAWLGSCGEGMSMVDLDLGILDVAEEKYCIRADRCRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1D6</accession>
    <name>A0A6A6P1D6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_342585</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1D6"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.20.10:FF:000001">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Beta-galactosidase" evidence="9">
        <location>
            <begin position="426"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1029" mass="113290" checksum="70203930D2700405" modified="2020-06-17" version="1">MERLHFTVYVFGARRNLIMQSISFFLRLLFVLCWIGWASVPGVSAQEDGSSQWPLHDNGLNEAVEWDHYSFKIHGERIFIFSGEIHYWRIPVPEVWEDILEKIKAAGFTSFAFYGHWGYHHPNPSTLDFENGAHDITPLFEIAKRVGLYVIVRPGPYVNAETNAGCFPGWLTTGEYGTLRNNDTRYTDAWTPYMSEYSELVSNYQVSQGENVYLYQIENEYGEQWIGDPTDKVPNPTATAYMDALEATARANGIDVPLIANDPNMRVLSWSEDFSDAGGNVDVYGLDSYPSCWSCNLDECTGTNGEYVAYQVMEYYSHFQEVAPTQPEFMPEFQGGSYNPWGGPQGGCPEDIGADFANLFYRWNIAQKITAMNLYMMYGGTSWGSFAAPVVATSYDYSAPISEDRSIWSKFHETKLLALFTRAAKDLTKVERVGNSTDYTTNPMIMATLLENVDNGARFYVTNHADTSLGSLETFSLHVNSSAGPLIIPQKGGEVTLNGHQSKILVVDFNFGSHVLLYSTAEVLTYAVTDVGTILVLWVPTDESGEFHLKGATDGSIAKYQQGSNVEFFEDDEGIITTFTQGQGMTVLEFENDVSVIILDRKSAYHFWAPVTSNDPSGPADEIVLVHGPYLVRGASINGDIVYIKGDTSEACSIEVYAPGNVDTISWNNETVNTTKSDHGSLIAELGGPDMSEVVLPALDSWKVHDSLPERLETYNDSGAAWKGADHVETPNPTKPATLPVLYVDEYGFHNGAHLWRGYFNGTANGAYLRVQGGLAFGFSVWLNGQFLDSYLGSADSSSGNLTLSFANATLNDAEPNVLLVLQDNTGHDLRAGALDPRGILEARLIGGDFTHWKVAGSAGGTAVLLDPMRGVYAEGGLTAERLGWHLPGFDDSAWDAGSPSEGLTGAGVNFYRTVVPLDIPQGLDVSLAFELSSLGPSDQVRVQLFVNGYQYGRFNPHIGHQIEFPVPPGVLNYGGDNTIGLAVWAQTEEAASVGIELKKKYVLESSFSSRFESEYLRPGWTPERLQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2R4</accession>
    <name>A0A6A6P2R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative MFS allantoate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_15960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2R4"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="88"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="536" mass="59786" checksum="56523AF9C8E3F75B" modified="2020-06-17" version="1">MADTKSIETPSDRRDSDKTASERDVEKEPIPGISADAIRAGEVQPEKVLKHAVDADEALKAFAQYGGQVIHIDEETNRRLLRTIDWHLMPIMCVVYGLNFLDKTTLSYASIMGLREDLNLSGQDYSWLGSLFYFGYLAWEFPTNRLLQYLPLGKYSAFNIIMWGTVLACFAAVENYAGAIAIRFFLGLFEAAVTPGFALFTSQWYTKKEQGTRTAIWFSFNGWAQIFGGLVAYGIAVGSAKHGSAIAPWKIVFLVTGLLTAAMGVIFLWAVPDNQMNCRWLNKEDRILAIERIRINQQGVGNKHWKFYQVKEALKDPLTWAFVFYSLVADIPNGGITNFFSQLIVGFGFTPEQSLLYGTPGGAVEVISLLLCGYLGDRFGHRLLISTSGLLTALLGIILIVALPLENDGGRLAGFYLTMAAATPFVALLSLISSNVAGYTKKTTVAAMYLVAYCVGNIIGPQTFRADEAPRYVSGEVTIIVCWSLCVLDIVFIWWYCRHMNRKKEAIRNAPGYVKLENQEWLDLTDRENPEFVYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2S4</accession>
    <name>A0A6A6P2S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_342188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2S4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="76" mass="8500" checksum="E7EC22C9F0BD8B5F" modified="2020-06-17" version="1">MHAKGPSIQSILSALELLLQAFPSHFPGAARDRLSNPWPDATQLPASLARLPSFPGRLYALYLHIRAYIRLHAYHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2T8</accession>
    <name>A0A6A6P2T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_411900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2T8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="18497" checksum="F453A9FBAF3D2444" modified="2020-06-17" version="1">MQRHSGTLHGGNALCGKYSNLADETQHCVSAATTQIAQMTRREDENHAVTSQLEHAYGSNFAPGFQTVQWPCAGIVRRESAPAGPSLSQGSPRRGRWNRGQAGRSNSMEAPGGCAMTTWRNSEVSDDAELVGHAGGAVLLPRRRTSFGTVQGLKDIAAVAASEKVSSARTIMTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Z0</accession>
    <name>A0A6A6P2Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Z0"/>
    <dbReference type="OrthoDB" id="3832538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="534" mass="57652" checksum="CD1393FB47D77383" modified="2020-06-17" version="1">MNDAWFAQVPDSTARDTTNGAEVAGGTAIDRVKTPLRFLKYGSRIKPRKTNEMGHTGEQPRSSLDPPTGTVQRVSKGAGGSSADISSDGSACNRSRTSPPEIVPASSTLDLTVIEEPEIPKTCNVVVDVKDALFSNPPTPRVVTDIHYCANDHGNHPPGATNESSLSRAPSKNQIEVTTSISSSTEPISSYVSRSQSAATSASTDTTYATGKIGQCRKAAIRADLSPMEVAENRTRTVASRVKNSRPRKAKDVYEARRTIDEIVRKPVQSPQTSQPVSQPSTTSVPSTAPPTYPTPFQGHTTAHDMRGALQSNDFQSASMSLDGCKELHPRAQLAMSPVILVAEQAPVLESRRGTRPSQLALEDRRRGWSSAVAARDTQCPSGIDPVVPEGNTGCFAAPMERLGAPSSRSHCDVLKPLLDDSTRDESYDQPSMDDTLRLSGHGTIYECPRRENSRRWFTCAGAESTCEGSIRRTEPGESACLEARVEALERENELLKAALMAVLKTTSQPATYCVCSRGQYAAARHQRQENEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Z3</accession>
    <name>A0A6A6P2Z3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_219127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Z3"/>
    <dbReference type="OrthoDB" id="3763505at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="136" mass="15167" checksum="DF36B81F25447A2D" modified="2020-06-17" version="1">MSEAMQSTKDERGEAKRFDDGENGKTYNTGDSLVVTHRSTSPAICGLITGERTGPDVFHSLWSYVRDHCLFTVYKAQKKNSSSTFPRSLPALQPQSEHQQQQTAPSSKTPKTRQFHSMIICAHSHPSPFSLTCLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P308</accession>
    <name>A0A6A6P308_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-protein ligase Sel1/Ubx2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_342020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P308"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025376144" description="Ubiquitin-protein ligase Sel1/Ubx2" evidence="4">
        <location>
            <begin position="35"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="817"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="775"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="850"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="862"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="885" mass="98327" checksum="22BF9D4DED66AD5E" modified="2020-06-17" version="1">MRSARELLTMNQWSLRRWPRLLLLFAVICGVAHALKYHDPLVGELHDVEPPVAPGNADDGSRQIAEEHPIPGAAAVDEALSLLRRVQPSPAERYHSYRRPSGVLATTTYYAKELFFLLFMNGPPQHDLLTSHDYERPPKLEQPLHDAVKLLSEAAAENNPDALYILADMNFYGNYSHPKNYGEAFRRYEQLAELNGNSSAQHMVGFMYATGIGGAVEMDQAKAMLYYTFAAEGGDIRSQMTVAYRHHEGISTPRECGNAVFYYRQVADRAIAYKRSGPPGGHPMYKEAVRIADELGGVYGEGASHSSSGPNARQSGPSSDAYAAFEDFLEYLDLMHRKGDLKATFSLAKLHYDGTRVLEQDYGVAKQKFLEVARKYWNKDGSRTDVPPATAKLAAKAAGYLGRMFLRGEGMEQSFQIAKTWFKRGVEHGDSLSQYSLGLMYLHGLGVPRDPVLAAEYLAPAADQDQASAQVLLGALFLDQGDVSTAIRYFETAARQGHIEAFYYLAELSDQGIGKERSCGIAAAYYKIVAEKAEPIVSSFIEANEAYEAGDIELALVDWMMAAEQGFEIGQANVAFLLDQNAQPRWSISLLFSFLVDALKLSWSSSKRATTGLVNDASLALIYWTRSAKQQNIDSMVKMGDYYLSGLGVPGNSSGKLNEEKAAACYTAAAETMQSAQAMWNLGWMHENGVGAEQDFHLAKRFYDQAFETNSEAYLPVTLALLKLRARSAWNTLTHGRVKSIQNEPSPKRPRTLTEWISDFLKNDAAMYAQDYDDVDGTVEDPYEPDDWDPHHPHGHHPRNAGDDYYGDDEGIPDDSIIESLVIVALATALAALLYYRQLRQLEHRRRARDAQEGADAEGQEEDRGVFPRLDDPEWNNWVAGGIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Z2</accession>
    <name>A0A6A6P3Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_341229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Z2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025679587" evidence="2">
        <location>
            <begin position="17"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="92" mass="9940" checksum="97F0519889E799B7" modified="2020-06-17" version="1">MSDVLLVLLLVLGAVTQPSVVWAPLCPDAELSSTQGVQSYDYDSTRRPLRPSYPISRTSPCPLPTRQDASCGQLSRTKLARSLSPPSPSSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P495</accession>
    <name>A0A6A6P495_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_209739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P495"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="240" mass="25187" checksum="7609B099356A6C2E" modified="2020-06-17" version="1">MGQVKASAAVRVLPHRSSPATAAAPASRLRPPRRRRCWISPSIARLCGRRPACLTSWPRPHVSGRPRPSPRTGMPHAPGGREHRLPQAIRRSIAVLDRVRSPIAPDCHSGLPAGPQASPARRSAPLNAHYCSSPRAGSNPTADARFVCTSIALSTSSTTTTRAGQLSPLLLSFCATPSCLLLPPPSPYPLPAGPASLAAANPPPGTGRRPRARRATHARLRWPAAKTSAYAAGIWGASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4E3</accession>
    <name>A0A6A6P4E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cora-like Mg2+ transporter protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4E3"/>
    <dbReference type="OrthoDB" id="2830640at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="46300" checksum="BFA44AEACE432EA0" modified="2020-06-17" version="1">MTPTTSDNCAVQLLRRDQAAGVDLPNVLPAEVETIIATSKAQFIVLFASALHIRACEHCRTLFSYHFKVPSIFWENSCKKANGYFGCQNVIQENGLRKGYTTWLRFKVKQMHDVPNSSKGSSGYDWYSPTYFTRWFTTGQNILISFDTPPSLMQHISKSLLFDESSSLSAHDPYWVLAKLIQEVTESQDKSVWGIRDAIRRVEQSRNVHQQRPEPDYHRFHDLARHATHSVETLEVAVNTISHVIQLHEVFLEENKLLPGDPAIATRKQVKLQLQFLSCLLENFKFRAQSNKERLQNEINLAFNTVAQYDSRISVRIGKAVQNDSASMKTIAVLTMLFLPATFVSALFSTTFFTFESNEDGVPPKWFVSDKLWIYFIVSCPLTVVVLAFWSIWHRSLSSKQFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5H9</accession>
    <name>A0A6A6P5H9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fip1 motif-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_200151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5H9"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051187">
        <property type="entry name" value="Pre-mRNA_3'-end_processing_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484">
        <property type="entry name" value="FIP1-LIKE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484:SF0">
        <property type="entry name" value="PRE-MRNA 3'-END-PROCESSING FACTOR FIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="276" mass="28477" checksum="1D9956750A65FE67" modified="2020-06-17" version="1">MAMGESAPLRFGAPKPTEPVRTPSASNEMQRTAQPAPPKAAEAKPTAPAQPKRPGYTYPEVHTSNVDVNVNPVWDPAGKPITEVDIDADLAEHDKPWRRPGADQSDYFNYGFDEFTWTTYTMKQNAMANALKEQKAESANFERMFGGGAPGLPGAAGTNTSPYAGGVSSPAAMSAAPGMAPGMYPGMPDMSPDDLMAAMGAHMRAQGISDPNQLDFGEFMKAMGMPGGGGAGGTPQPPAGPSGQTAPNQQGVFGGGGPYGGGGGSFGRGGGRGRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5I4</accession>
    <name>A0A6A6P5I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L6, alpha-beta domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_339522</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5I4"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="97"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21912" checksum="72BA1778BCFC1B79" modified="2020-06-17" version="1">MKYIHQQESLTIPEGVKVNIKTRIVTVEGPRGKLSKNLGHLAVSFSHPKKNVINIEMHHGARKSVAALRTVRTIINNLIIGVTKGFKYKMRYVYAHFPINVNIDKNKETDLFEVEIRNFIGEKIVRRVTMRPDVNVETSKTQKDEIVVSGNNLEDVSQSAADIQQSCRVRNKDIRKFLDGLYVSERGNIVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P688</accession>
    <name>A0A6A6P688_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-dependent phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P688"/>
    <dbReference type="OrthoDB" id="550558at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844">
        <property type="entry name" value="SER/THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844:SF2">
        <property type="entry name" value="SER_THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="266" mass="30044" checksum="BFC9A4CBFDF8A0E3" modified="2020-06-17" version="1">MAVQILSDLHLEAPKAYDIFEIVPKAPYLALLGDIGNIAPHKNDCIAFLTRQLKQFRAVLFILGNHEAYHSMWSETLDILHAFEQDVRNNASLGEFVLLDRAIFELPGTNVIILGCSLFSFIPPESEMAVSFGLNDFFQINDWDVEAHNEAHRQDVAWLNAQVAELQQRNVKIMILSHWSPSKHARSIDPKHAASPITSAFSTDLSDQVCFKNDKVKVWAFGHTHYNCDFMVKREGDAGPLRLLANQRGYYFAQAEGFNGEKTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R0</accession>
    <name>A0A6A6P6R0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitination network signaling protein acrB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_370368</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4158994at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733:SF8">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="466"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="596"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="774"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="831"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="989"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="920"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="507"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="614"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="682"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="800"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="847"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1270"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1291"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1326"/>
            <end position="1345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1345" mass="139756" checksum="4630AE942DE398F1" modified="2020-06-17" version="1">MPPKGTRKTNASSHHHNHDGSASTRRHNNNNHHQRENGLAPPAATAAASSSSSSSLPSAAAAAAAGKRNLARAKSNGNLNGHAQNGRPAANTSSPPPPIPSAVDLENASSSSLSLSASSVSNPSPAHPHHVRQQQSQQEQQRKQPDTFATNGSLARTNMAASPPNAKGFVAADDKYRQRTASDVSLDAVDGYPHHFDNANGGVTDMSATSSRAGNGSVSGGVHRPDFGSKNRGGAAYNGNTLAIAKTILTSCPLRDVIAILIILLQLPPMILMLVHMLFTLLTFVPPSTGASLSALPSLTEMIQGSGGMPTLPVVLVVDVFIYILWFSIPWLPVQNVFLDFAEVVMAVSLGGAASASSGATHSMLLCSAIVLAARAWQASDARALILQPLSVFLTAGGSGAAGGAGAARSSSGGGAVSAFANRLLDFSTAYLRSPNSTIYSPPTLKRSILGVHIVSQGLVRLVRRHLSRHREPPSAATASGGPLSPTKRSDPEAGVPPQLAARLAGSSLVDSSSDIASNSSTDGRPPGPSPAGGGGSGSGGVSKGASGAAGDGKEKVSSGSNQKSKRKQGMYVRSHQPFWAALASTKVTVFKEMEQTQASSDAAEVPARRGSSSEEEEDTEDELDYIGSANFVTDEDRVWITGITTTDVAFGVSLIRWARSVSGDDFGDGGEGSESGESRRGSGSSSHSGGAYLGSAKRDDCGRPFHVRVNGADWSSMTVRKNGTRFSQEGEPIDVFAGEVYGLMPLSTYYCEFVRCSTGAVMYGAHLITQDQPSGSATNHAHHHHAHHHHHHHHAHQSLRPSSPTTTLKTSIAATETKNAELRNILKRRRREHQRAVTALRKDNEALSNRLATSGGSDDRQRQRLLQYRQSARQAEEAAAKLSDEIAALGEVPADDEVGEAKEVRARWADVKAKCDAVVEAAHRERRKWERKVEEARAELAATAQKQQKLSQRKTKAEEACAKLLELQQRRGPMSVASSSPAGSASVLSSAALSRGPGSQSSASVGGAPQQAASPPAPAPQPPPGPSSQPPRRLSDRIVPPQPQPQPQPQSQPQPPPPPPPPSSPAHASLVAQHRAYYARLEQALAHELANVRAQTESAAAAAQQVRTQCAGLEALYAQMHQQQQQQQQQQQQQQRHHHHHHHHPGHAHAHQHAHGGHGLAQAQQSGQRDEPPMTPEGPLPGTGTAAAAAAAGASLPAFQFPGSAAFGSPAQAAAGLVGVGGGAPVPGLAGGGGFAGMGAQAQMQTHGHGHGQGQQGQQGQGQGHRGRSSSMLSSASAFTEDNVPLEVGEQAEAEVEVEAEVRGPVELGSDAVGCEGQGAGRKGSSGSESSGSAGSASVGSARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T0</accession>
    <name>A0A6A6P6T0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">mRNA 3'-end-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_274111</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T0"/>
    <dbReference type="OrthoDB" id="1914176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000012">
        <property type="entry name" value="cleavage and polyadenylation specificity factor subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18345">
        <property type="entry name" value="zf_CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="170"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2459695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="211" mass="24446" checksum="817A3CAC20C51A0E" modified="2020-06-17" version="1" fragment="single">VAQAVEQILNPSKAPRPKFAFDDFLKREYRFGLDPNRPVCKAYMQGHCPLGNNCPDKHQVSSSYNNLVCKHWLRGLCKKGDACEFLHEYNLRRMPECNYYSRHQTCSNGDDCLYLHIDPESRRPACPHYERGFCPLGPNCALKHVRKPPICPFYLAGFCPNGKACKDGPHPRFPEDLKKPEPRVEKSREEVELERAQREADAQRDRDRDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7E9</accession>
    <name>A0A6A6P7E9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAR-17a/AIG1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_176873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7E9"/>
    <dbReference type="OrthoDB" id="419711at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32597" checksum="268B3A2FE01BCE97" modified="2020-06-17" version="1">MSRFLRPQSRDLPFDPEYRFFTSWLLSPVVLFGLRAVIGLYAFIAILYSLGHDSASGNELAAQRSFDYFTNLCYWGLAFYFGFSAAHTGSYAFTGRPWLASWPRFLQVMHAVFYTTIVVFPFLVTIIFWGVLYDGAATHDSHYYWSNVSFHGLNSLFGLLEIALPRTSGLPWWHLIPLTVVLGAYLGLAHLVQATQGFWVYDFLNSTKHKRGIVAAYCVGIFIGMLVVFGVVHLFVKLRRWATENKGLMLGKFAEKDVARREMTESAKETIELREGAGTRQEGEQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7N4</accession>
    <name>A0A6A6P7N4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_180015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7N4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="10798" checksum="C5AD6C3DC09EDC78" modified="2020-06-17" version="1">MPVQQNFGSHLGPKLIIQGRQLDGVVPPQTLISRIGWTAPAMSDVKPSLEQWLLEDRRDEFWNAPRPHRSEQQIREELDRLDAIIRSRTCSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7N9</accession>
    <name>A0A6A6P7N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_183368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7N9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16961" checksum="AF1F7AED3247BD07" modified="2020-06-17" version="1">MRCCTQGRVRLTRNLSAAMQSANGPCRASCIGTAPLSPCLCYANSCLAEPVSCLFSPALPLLHFRICGPSVTTTAPHKILHFRLHAASRVLSSRNHATYRRAGKKYQSAFRRPHQRPERNEPLHAHTAVHSVSDSLNIAGHGNGVPVWPADEQFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7T5</accession>
    <name>A0A6A6P7T5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3752 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_281345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7T5"/>
    <dbReference type="OrthoDB" id="73491at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3752" evidence="2">
        <location>
            <begin position="156"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="33126" checksum="45E15D3E77DD6818" modified="2020-06-17" version="1">MPSIGPSLPPHLAKRKRSDSSDGSISSESDSDSASPAPAPKPAPAPTPSIGPTPPPARADSPSPSGGKRRRIIGPAPPPAPLDERPPTDPEDSAEASGSESDSDSSDDWGPAPPKPGDSASGAGAAMPGDDDFASGDGSGGGESGKLARDEWMTMPPTQDDLAARLDPTRARPRRFNTGRAARGGSSNNGSGGGGGANMWTETAEQKRKRLEDEVMGRTKAKASDTKEAARSSRTKEDRETAKRVRKQAEKERGKSLYEEHKKRVGREPDDDPSKRAFNYEKDVAGGVKVGYTQRKEMMNRAAGFSSKFEGGSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7V4</accession>
    <name>A0A6A6P7V4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat-containing protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_407701</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7V4"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000157">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="214"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="422"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="503"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="602"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="644"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="692"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="841"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="752"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="752"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="974" mass="107006" checksum="58455EB184E17650" modified="2020-06-17" version="1">MVKSYLKYEHSQTFGTVTSATSNAVWARDASGGTRATGAGRAFVGANEEVLSWDVKKGELLSRWRDSRCSAQVTAIAQSKADRDVFAVGYADGSIRIWDSRIDSAIISFNGHKSAITILDFDSAGVRLVSGARDTDVIVWDLVSEVGLFRLRGHKGQVTGLAFLPIPAPTAEYGSDGQLAPMAEATQDFLLSTGKDALIKLWDLSSQHCIETHVAQSNGECWSMDVSPDGSGCITGGNDGEIRVWAIDLEGLYASSTQPNAATDQRYLYDRGALNRQGKDRTTGVSFHPSADYFAVHGSEKAVEIWRIRSEGEVQRALARKRKRRREKAAASGDVEMEDGDNVDGIASAQIGDVFVPYVVVRTGGKVRSMEWAPGSKHKSIQLLVAMTNNLLDVYDVPTKSSRKSSKGEEPPEYSRTYSVDLPGHRTDVRSLALSSDDRMLASASSGALKIWNVRTQTCLRTLECGYALCCSFLPGDKIVVVGTKGGELELFDIASSSLIESAQAHDGAIWTMQVHPGGQSIVTGSADRSAKFWDFKIVQEEIPGTKRTTPRLKLVHKRTLKLNDDILNLCFSPDSRLLAVSTLDNTVKVFFVDTLKLFLNLYGHKLPVLNISISSDSKLIATCSADKNVRLWGLDFGDCHRAFFAHDDSVMQVAFVPHPISADESHYFFSASKDHALKRWDGDKFELIQKLGAHHGEVWAMAVARTGDFVATAAHDKSIRLWHQTDEPLFLEEERERELEQLYESTLAANLDDDGGANVAGDDEDDTAGPRDELAAASKQTVETLTAGERIVEALEVGMADLAVARDWERRAAAAQQAGTSIAPPQRDPLFLALGGISAERHVLNVLSKVPPGQLHDALLVLPFSAVPSMFTFISIWVRKGWNVPLACRVLFFLLKTHQKQIVASREMKELLEEMREGLRETLNREKDTMGFNIAALRFIGDRVRESGIGRLEDVREQEMLSGRKKRGFVDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7W1</accession>
    <name>A0A6A6P7W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7W1"/>
    <dbReference type="OrthoDB" id="5385189at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="323" mass="35509" checksum="C2FE3A1422413849" modified="2020-06-17" version="1">MFHNQPYATPALPQQSPPLAYLPAVCEAMFPEINDRLLWLGVGAFSFLAVTAVSYGLRELSYLTEVAPPRERPRKVSQETEDAIKLESLRTLASCNNTDIRRVATKMICDRFLTDPAAVAQLHADFQSTNPRVREAVSAAVRLLDRHCGSSKWRTPPRSPPTTLGPTYTFSPHTIDSPGGNDPSPSPASTRSRWATARNFNQSRARPLAEESPEEQALRRRRREAMVLNEGDRPVSADDIIQRGGRVLDEEVRRTERALATLANGTGTDEMPSHNSPPRPQRRSTRQDSIGSVHSIVESAAGSGARLAPSIAGDDIIVEDERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Z7</accession>
    <name>A0A6A6P7Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6987 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_280914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3937590at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022124">
        <property type="entry name" value="DUF3659"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054256">
        <property type="entry name" value="DUF6987"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461:SF1">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12396">
        <property type="entry name" value="DUF3659"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22485">
        <property type="entry name" value="DUF6987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1486"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6987" evidence="3">
        <location>
            <begin position="1339"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1545"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1569" mass="164134" checksum="D519BADED4315146" modified="2020-06-17" version="1">MPSPAAGKAGDAPRTPTKLGRKGGQAAAGSASKLGQSAKGAASQAQKAPEQATSKASEVAEKSPQLPPRPGPEEAKRKVSQPSELEEQEPMPVDEPEEAVSGAQEQSEGLSSEVEDTGDDATEKAGDIGEEGEETEDTEEGAQQTGRGLLSGAKGLADRASSMTGNAKQDPQKPLGDVKETAEETTNGAKETVQDTVGGAEEEAGDAAEKAKGAVEDTTGQELPNMPDLSVLKGLEVDEEGLIHDESGRAIGKLVEGDAEDLVGYQIGDDGEILDDDGDLVGRCELLPETAQEQIEKAKAEAEGVTDGELKLPDISILEGLTVDPTGMVLNDDGDFVGQLMEGDPSELKGKVFNAKGEILDDEGNVIGRARVHPDAAALVDKAEQAEEQLPDGVGVDGVPETAEGAEGQVDGVKDTLEGAAPEGAVPEGALPEDVELPGLGALQGKSINEAGEVVDSEGDVLARLAEGDVDDLKGLTLNDKGEVVDSDGNVLGKVELADGAADKLKEVASQLPLDLRILDGLKVNKKGKVLDEEGEPIGELVEGDVKEAAGKFVNSNGEVLDKSGNVIGRVQIVPGEAATNAAAALKERLAEAEEAVPAEPKLEIPDLDILDGLKVNKKGQILNEDGEPIGELVDGDLKQCAGKKVNDKGEVLDKDGNVIGRVKTLPQEVEAAAEEAGEGAEEAAEAAAEDAEGAAEEVEEAAEEAGDQLPDLSVLNGLTVNKAGKLIDANGTVVGELVEGDAKKLSKSGVTCDAEGKFWDNKGHVIGRAQTVPVEEPEEEAPFAGLEGLIVVKGGYVQDENGITVGQVVEGDPKKLVGRAVDEDGDIIDKKGTVVGHAERVEEEEEPEEEPVDMSFLAGKTVNKQGNVIGDEGVPVARLVEGSPKDLAGRKLDDMGQIWNDSGKVIGRIELIPEAEREAKPEGPFAGLQGLRVVPDGKIADEDENIVGEIVEGNPKRLIGLAVDEDGDIIDKYGNVKGHAEPLEEEEEEVPDLSILDGKVLNKQGFVVDDKGIPLGRLVEGNVKELAGLKTDGEGLIHNDTGKVVGRCELIPENERVAKPEGPFAGLEGLRINKEGMVEDEDGNIVGQLVEGNPKRLVGQPVDEDGDVIDKYGNVKGHAEPWEEPEEEPVDLSRLAGCTVNKAGNIVDSSGAVVGRVAEGDVKNLIGKKVDGEGQIWDNAGNVVGRAELVQGFDQGPEGPFAGFESISVAKDGTVVTPDGTIVGRLTEGDPQKLVGYKVDENGEISDKNGNTIGVAERWEPEEKERHVSPMSGMRVNKEGEVRDENGDLIGKLTDGDLGHCAGMEIDDNGNVVDNDGNKIGEVTLIDLIQEEEEGPSEEELQRQKDAEIADKMANICQQTLERIQPVCKQITEHIERADRTPRDELDEEELVNQVKPLIEEGGRILQECNGALRGLDPDGRIAAQAKGRAGTREATPEEYRLADLLKELTGTVVTTIDNAKKKIADMPHAKKKLNPLWALLTEPLFQILAAVGLLLSGVLGLVGRLLSGLGLGGLVNGLLGGLGINKLLDGLGLGSISEALGGGKEKKKSGGGASGLPVIGGLLGSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P824</accession>
    <name>A0A6A6P824_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Taurine catabolism dioxygenase TauD, TfdA family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_273193</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P824"/>
    <dbReference type="OrthoDB" id="406634at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="8">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="119"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="362" mass="41295" checksum="08644B3081469DB5" modified="2020-06-17" version="1" fragment="single">LDPAWLRDACRCPRCVDPYSGQKTFDTGDIPAGLRCRRAQGAGGAGTVTLEWENDVPGFGEDHRTELPIVELRTALRENGDPRGGIPRRADRPAHWDKDELLKSDLWHSYEGYMSDDGALLKLLAQLQRYGIVFLKDVPPSADAVSDIATRIGPLKETFYGRTWDVKSIPKAENVAYTSQYLGFHMDLLYFIQPPFLQLLHTLKAEATGGASIFADSFRAVNSIRRSKHALWLALNTVPVKHHYDHENHKYEHSRPTVELDGRARDIAYVNYSPPFQAPFVRAKPGWNLASYHAAIAEFKRIIELEHNRFEYRMQEGDCVIFNNRRVLHGRAAFKEDGERWLRGAYVDEDDFISKRKVLMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8W6</accession>
    <name>A0A6A6P8W6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_334983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CYC8/SSN6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8W6"/>
    <dbReference type="OrthoDB" id="418911at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000403">
        <property type="entry name" value="General transcriptional repressor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000078">
        <property type="entry name" value="Transcriptional corepressor Cyc8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="298"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="332"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="412"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="710"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="750"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="771"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="797"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="833" mass="92436" checksum="AD334D4CB5D1F109" modified="2020-06-17" version="1">MASQQHPSPTAGMPPHHVQHPSQPQANGHMPVGVPPKTTAQYAAQVNENTWFQIGAVCQLQNDEDGAIHAYQQCLRHNNWSVPAMQAISAILRNRDDFPGAVDYLKNILKIEPNNGDTWGSLGHCYLMMDDLQQAYSAYQQALYHLQDPKEPKLWYGIGILYDRYGSLEHAEEAFSQVMRMEPNFEKANEIYFRLGIIYKQQQKFAQSLECFKYIVTDPPRPLSEEDIWFQIGHVHEQQKEYENAKAAYLRVLDRDPTHAKVLQQLGWLHHQASQNFQSQEQAIEYLEKSVASDQNDAQSWYLLGRCYMSQQKYPKAYEAYQQAVYRDGRNPTFWCSIGVLYYQINQYRDALDAYSRAIRLNPNISEVWYDLGTLYESCNNQTADALDAYQRAADLDPSNVHIKARLQLLQNGQPTNGMPNQNSAPLPQDVHPQAYNPSGNGPPGPIGPQWGSGPPAQPQGPPAPANGEWNRPLAEVRNPPQMPPQQLNPYDQRDGMRPPAHAPPRPGSPPRQDPIRQYQEARPTPGPPRRNMSPSPKSHNVVPSLYQGPQSAPPHQPPPQSQLPPHQQPPQNRITNPNYGTAAHPSSVPPPPPPNISAGPNQGPPGGPYRMPSPAPEVRPIHDSGPRSPAGGYGAPPPPYPPPAAIAGGAPAPPSMVPDAARERDERTPSGPKRLREWEDDESDKRVRLGDPSRRPSPPDRMQSPPRRSPPDAEARRLEEQRRANEGYHPSEAAHHPQALPSMAAMQHGPPPPPPPPPPGLPQMGSDVPQPKEEPKNHHEPAARKMEVDEDYDDSASEKNNVKPPRSGRESPRGTSVANGVPPPPGAAEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P946</accession>
    <name>A0A6A6P946_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_163971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P946"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19382" checksum="F18A2B5C88C01D8F" modified="2020-06-17" version="1">MSTRWAGGGMGDGVQLLRLGAGRTPFPHQRRLCGCDRRWLQHSSEKAARKCPSGMQHRKLTANALTPRRGIRSNESAPLASVASRVEMPSRDYKTASRARPNQTVSLLALQLFAFLSPGLVPEDPAYTPARSFSCYGVEREPSTTTYIGVAGSRNPKSTIRSNPPCSSRASTLPTIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9G2</accession>
    <name>A0A6A6P9G2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9G2"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="276" mass="31374" checksum="228A52A39B2D5ED8" modified="2020-06-17" version="1">MSIHSPSLHSTTSIAQTTSQLPPHINEGCYAIKNVGLGAVGVGLTSLILRLDKGRVIKVPKTFTADDFPRRDVDYVEYMNDINREALELEQRIYKRLEDHLGIIRCMKMSSNGIELAFAKEGDLESYIKTNPEPHDHLKIKWILSLITTLSYIHSRRVFVDEIALRNVLVNEEQLFYSDFGNSCLLPVTADVDTACENGVTVKIEILHLGWIIYSIAVWAVHKYYYFGHGDPQWPRLQDLPPTDHVYCGPIIQKCWNGDYKNVEALNKDMLSLLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9X4</accession>
    <name>A0A6A6P9X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HotDog domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_130941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9X4"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF7">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G10800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="115"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="250" mass="26128" checksum="865C0A41EEDA7BA6" modified="2020-06-17" version="1">MAASPTVPALASLAAPLTDAETLAAFDPAPGSAAARTAAHIDAHPLVGALRADPRFVAARPHLKIPAAMRARNLTAGTLLADDAIPAPPLTFATRDGSALVAVYFLGDALCGHPGIVHGGLLATLLDEGLARCCFPALPTKVGVTASLKIDYRAPCRSGQYVVLRAETTRVDGRKAWVRGWIETLPDPDPDELANGSSNGVLANGFANGEKRVNGVEKKEKEPVKLVEAEALFVEPRGASKMPRIYASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9X8</accession>
    <name>A0A6A6P9X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_333290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9X8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="11279" checksum="F9FB3887171E5AAF" modified="2020-06-17" version="1">MCCMRWYLQSTFLPHIYSSLYTSRAHMCDAPGRASKAASVRAIAKEHVMYLHNTYCPARRRRSIAPFSSLFSQLCTPPQERACGGQRVGDGVFCNRSVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA72</accession>
    <name>A0A6A6PA72_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_280415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA72"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF5">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="19"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="359" mass="37542" checksum="5A659CA23CEF38E7" modified="2020-06-17" version="1">MADIQIPKTYKAAVYDKPGTISTKIETLETPEPGPGQVLINLTHSGVCHSDFGIMTSKWLHLPFPTKPGQVGGHEGVGKIVKMGPGTENSGVKVGQRVGVKWVADVCSSCPPCLSGYDGQCFAGKVSGYYTPGTFQQYVLGPAHYVTPIPDGVDSIQAAPMLCAGVTTYAALRKSNAQSGQWVVMLGAGGGLGHIACQIAARGMAMRVIGVDAAPKRQLVLDSGAEHFIALPAPGGNGGVKELTGGLGAHAVLVLTAANAAYGSACDMLRFGGTVVCVGVPEGEPMPVRGCVPQYMIARALHVVGVAVGNRREAIECLELCQRGVVKVHCRTEPLENLTKVFEEMHSQQLQGRVVMDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAJ0</accession>
    <name>A0A6A6PAJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleophile aminohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_383787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAJ0"/>
    <dbReference type="OrthoDB" id="77601at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.30:FF:000007">
        <property type="entry name" value="Similar to threonine aspartase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="402"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="456"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="648" mass="68603" checksum="D5695693BC41B1CB" modified="2020-06-17" version="1">MFSPKAHNDGCVIYVHAGAGYHSHANEEVHLAACRDAARLGMAVIRAGGTAVEAVESAIKVLEDREITNAGYGSNLAMDGVVECDASIVDHFGRSGAVGAVAQIKNPISLARILYDNTTREMSLRRVPPNLLVGQGATDYAFENGISILPFDAIVSPAARERWYRWKSDLRYAERKNKDAKIHQTPEDPLRAQVRNNRTREEYAEALLAEKEARRLALQTSKARHRAKSPSHATPPGTPNGSSPSQQSVAGITGMVDRMAIVPGSIAEASHSAFINSTQRVPTLSNYIDNNENGSQDGSDFAPSDAFAPSPVPSASFWQDGPTEPRDRDTAKGDVEKNGEELDGGETSSSLELPSITPSPSETPAAAPSARNEQEHSLSGTTEAQADIEGPMLDGDAEKAISNDEAEKKVDAEKNDVRKSRLSPTDNDSPNPSENAAVTLKVLPYRPKARGDDIIDTVGAIAVDSNGNIACGASSGGIGMKHRGRVGPAALVGVGAAVIPVESDDPDKVSIGVVTSGTGEHMATTVTAATCARRLYEGVHSPRKGHIGGNASTEDDDDILRKIIDKDFMGHPSVLHSRSAGALGLLAVKKTSRGTYLYFAHNTDSFALASMHSGDVHPACTMSRNSGNGDIALGARVVPKKNKGKKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAP0</accession>
    <name>A0A6A6PAP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_334053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAP0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="124" mass="14096" checksum="7DFE51A2D6D8452E" modified="2020-06-17" version="1" fragment="single">MGALRRFLSFSTDNSGCCLCRRYLLVLLLFLVSCETCVFCCAVLSCPLGYEYFFRVCSLSFTLFFKRPFFYPSLLSCSWCWCADSRAVPFLSCCACSRRAHCALFCALGRSPRLDLDDKDSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBS2</accession>
    <name>A0A6A6PBS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_85292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBS2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="233" mass="25403" checksum="106FDA15E240C36B" modified="2020-06-17" version="1">MIAARLARSSPLARNKMTCGSAYRRSPASVPSARLRGLGMGAPLTSELPSPNSLPFETTQYQAPPYLLLRPPTLIRRPPKRGPAGHLPIRRLGALEPSATRFPFVACTEHARPARSQGLSVVCGVQTRLLLAPTAFSWPSPAKGRAPPLKIAASFRVLLRVPVDSYHGAAGARWPLPRSLVRATIVQATIPFVSSRLPRYRFYCRSFFPPRLDSGFLSQLVRAIKLPTTDGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBV5</accession>
    <name>A0A6A6PBV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_383481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBV5"/>
    <dbReference type="OrthoDB" id="2104739at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="359" mass="40800" checksum="6C7D600F1349FB79" modified="2020-06-17" version="1">MAPAHLRHQSSLEEIIDFSAEPLLEADQYIKAKRKFYDIINRFEAADDSSRKYNRPVSKNQVLRAFFRSIAHATDEDRDIDFADKTLEEKVHSDLIEFAEYLLDTFFLPLKASANKNPQPSPVYHTVVKNGQGGARKYTGTEARVSTLRRSCLIRDRYRCVVSRNFDIVEGVERYKSNGNNAQDDDGNLLRDETSAFGPLEVACILPHTLMQTKADYTQQATLAILSLFDNGVVHLIKGAEINRPLNAITLTIAFHRLLGNFELFFTPIPGHQPHTYRIDSFAYIGDSLPITRTFYLTESRSIEPPLPRLLALHRAIGHILHLSGAGEYIDEILRDMEECVRTDSSTELSRLKLHRIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBW4</accession>
    <name>A0A6A6PBW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_397886</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBW4"/>
    <dbReference type="OrthoDB" id="397265at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22385">
        <property type="entry name" value="KH-I_KHDC4_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22386">
        <property type="entry name" value="KH-I_KHDC4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000037">
        <property type="entry name" value="KH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000051">
        <property type="entry name" value="Putative kh domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047890">
        <property type="entry name" value="KHDC4_KH-I_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047889">
        <property type="entry name" value="KHDC4_KH-I_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031121">
        <property type="entry name" value="RIK/BLOM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744">
        <property type="entry name" value="BLOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744:SF0">
        <property type="entry name" value="KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="ATP-dependent RNA helicase PRP5/DDX46/KHDC4 KH" evidence="4">
        <location>
            <begin position="128"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="KHDC4/BBP-like KH-domain type I" evidence="3">
        <location>
            <begin position="245"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="54581" checksum="BA80CBE5D0409695" modified="2020-06-17" version="1">MGEEPRKRSRFDQTEPEPKRHSRFDRRSRSPSSRTRETRRSRSPIGRDVQSPSTAGKSNDPAATAAQLAQEAAEKINAEIRKKRGVQHVDVPPIRSVSSQSNPKSPSSASGGQPLNTEPYTQDGDWMTDIEVNDLRNRYVLTKGQTQKMIKEETGADVTTRGEYYPDKRMASTAKPPLYLHVTSMTEEGLNLAVEKIQELIKQELPNLVDERRFRRREPEQFERDELGRRKWPDEKIPIGLEPVPGFNLRASVVGSGGAYVKHIQQETGCRVQIKGRGSGFLERETRQESDEPMYLHVAAPSRDQVDNGKALCEDLIDNVRKQYEQFKEHGGSRRHGHHHGSSDGHHGIGGQHGYGGAYDQRRGAAGSPVGRPGAPGAGSPPVPSAGTPNPADYAAQYAQYYQQAAEGHQDPYAAYGGYQNYLAMCYNYYNQTAQLQVGSGQQSPPPPPPGANGGAPGTAGIPPPPPPPPSEAPPPPPPPPGAPPGPPGASGGYNAVPPPPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC11</accession>
    <name>A0A6A6PC11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">37S ribosomal protein S25, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_376281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC11"/>
    <dbReference type="OrthoDB" id="5542239at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016939">
        <property type="entry name" value="Ribosomal_mS23_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37799">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37799:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13741">
        <property type="entry name" value="MRP-S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="238"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="278" mass="31078" checksum="46238081AE297276" modified="2020-06-17" version="1">MTHGNLAHRVRGTATQLLASRRLVDHAGKPRPPPWYEIIAQYPPTRAGAGVRPLQRVGKVRGKGTPAKLFQPLEIKYPEDELRTDFFEDHPWELARPRVVLEDGGNDQKKFGWDWGTGIEQPGKALDGESVVQRQIWLMRHAGLSKALAYDTARKEFYAVRHKEDVQRRVAREEALHVGAYFGLGALQVGMQLEDAAWDEAREWAAKEVQLARQLGAAASTTAQVTSAGVESGDLEAVAEEEGAQLEESLEMPVEEARLEEEGAGKERERVMEEVRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC47</accession>
    <name>A0A6A6PC47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tctex-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_332452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC47"/>
    <dbReference type="OrthoDB" id="10059120at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="13635" checksum="F5867B9A1236D31F" modified="2020-06-17" version="1">MAPPVSETRLKQIATDACEAALRSAEGYVHSSTPSWNSAIINSILNSLVSETSVDGSPPKFKYVVNSTIIQLQAPPAGDPEAKAAKRGLHSAQGAFWNNDVDGNWGFQYHGAESKGIDVVIQVLWVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC73</accession>
    <name>A0A6A6PC73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MutL C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_332455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC73"/>
    <dbReference type="OrthoDB" id="429932at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="3">
        <location>
            <begin position="782"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="945"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="945"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1085" mass="119673" checksum="95A1B50EDCC90A82" modified="2020-06-17" version="1">MSFSGGCSNRQRDSKAKATAKGLEEQQPSQTAQSTSRPIRPLPDHVVAQIKSSTTITSLTGVVEGLLQNSLDASASKIEITVDFRRGGCMIEDNGLGVPPAEFGVDGGLAKMYHTSKYVSHTDVHGSNGMFLASLGAMSLLTISSRHHLHRAQNTLVVHHSQVMARHVPSPPSHAILFREHGTQVIVRNLFGNMPVRVKRRAAAEDRTEQDRLWDGLKKSVVAHMLGWQKPVTVRMQDWSSTKTLNLVESTLKSDVAPFQEGDPKNGERISPALRRVLNPLTQAGFILPNQWGFWVPISATTPSVRIKGAISLEPAPAKNVQFICLGVRPITVESGYNELYDAVNRVFSSSNFGLFDDSDVEEAERERRKHDRRFKQDGFTNRRLRGSRKGVDKWPMFFIHIRLATDQGRAAPGLDDVLSSNSMIRNLIEILSAMVTEWLGANHFCPRKLRRRRNERHSGTTSESAPSTPGSDTNRLSIRGEESRADVKPNPSLPHIENGEIESPSLQPLSAKAFQRRKSPAEDSGRHNAKRIIVEGQQPFNGWSRIKSSKSSFFDDMCIRGAKRRKITPVTVTSERETTLPNTERITTGQNRRSGGISADHAVANPPTGLQCRPHNVDEENGAGSPATVEENEADADMPEDGTITWRNPDTNETLWINRRTGVVVHRPQSRPKSDGLRHRIGGTPGDAKRSIRLSSRQGLNQSDTLPTRWLDEFLKKWDNPIFQPTDKAIPRVRLDTFEPQSTGRGKYSNFFSRGNTEEDFLDATALGHKISKEALRSATILAQVDEKYILIKIRPSKRAHLSQAVAESELLVLIDQHAADERCRLEDLLAELCCPPTVEKASFRSKLGYCSGVNYMTLSNPLSIEVSAREGELCKAQAVRFASWGILYDVEASKSTDEGKETLVVMTLPPGISERCKTNPSLLISLIRSEIWALTENSERTTLSQVTTECSTSTQDPGAGPASTPTGTSIDAVGPNSWLGKISSCPKGILDMLNSRSCRSAIMFNDVLSFNQCETLVRRLATCAFPFQCAHGRPSMVPLVDLGSFNDIELGTIGSGFFGQGTRGASNVGFVDAFRKWRDAGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCG4</accession>
    <name>A0A6A6PCG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_87791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCG4"/>
    <dbReference type="OrthoDB" id="5279705at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="253" mass="28680" checksum="BCAE30B56A91E216" modified="2020-06-17" version="1">MIATSSYFYMPASPCAHPHLPFHHQPARPSPLSPRSGNERPLMSPCIFTMASANPDNAIARSRQSKFSKRAAKPNPLIHRSSDQVKECRRDLFLKRVQQDREEKRWDMRSDQIMRLDFLAQQKRWRAEQERNAPIPVTDEDLEQSIVENHSNRDHRGNDMDIRPSMQMISPSTCDAEQEVDAVQQQEDAELDALIAMMEESNTSPPGGDDKSSHYGSDDDDCHQIFSDLAGMENAAPEQFGGCEEDAMDMSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCI9</accession>
    <name>A0A6A6PCI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S12/S23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_278544</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCI9"/>
    <dbReference type="OrthoDB" id="1713912at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="145" mass="15908" checksum="ACE91EDAE2C03945" modified="2020-06-17" version="1">MGTGKPKGLNAARKLRNHRREGRWADLHYKKRLLGTAYKSSPFGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVGLMALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCJ0</accession>
    <name>A0A6A6PCJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Indole-diterpene biosynthesis protein PaxU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_332800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus outer membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMEM53 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCJ0"/>
    <dbReference type="OrthoDB" id="77878at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF30">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30866" checksum="D732E5E4EBB29C44" modified="2020-06-17" version="1">MAGQPKPNPLAAFQRLNDSVYLYDPSTATAPASADLVILCSWMDAAPKHIAKYVEGYVRLRPRARILLIRNEMPDMLVRSTSTARKQLAPALDVVRGAARPDAGAHVVLHLFSNGGARRATHLAAWFREAEGAALPIDAMLLDSSPGKPSYRRSLNALSVGLPKSPVLWLLGRVVAQFFLLAFRAVHFLTRRPIMITEAREQLLDKSLFNPKAPRCYLYSKADDMVGWEDVEEHVREAEERGFAVQTVCFEKSPHAGHIMEDPEKYWAAVQDVLPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCN4</accession>
    <name>A0A6A6PCN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_275517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCN4"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22682">
        <property type="entry name" value="Ribosomal_uL24m-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="37638" checksum="0BAF3C738FFBD780" modified="2020-06-17" version="1" fragment="single">RRYRARRLAEKAAEKARISRLTYLDRVKAQKGHEGALRRAARARAKEDWMLGPLAPKRDAGLAKETWGSVQAEVAMAPSIPEKMRMKTLDKWVETGDRVCVVEGREKGKIGKVTEVNWETETVKVDGVNEVDVATPEFLKKEDLQGPTTTMEKPIPIRSVRLVYKVKAPSSPVEEDVIVERVQVNYVWDPDTDEKVKERVIPGLGIKIASAPKPEPLTESDQPPDTLRIRTEELTWVPTLRTLPMPRGVIDELRNRFSKYRRQLEPGFERKLRAREAEQEAIKESVKTMMTPKAQLRMVQAEKRREEMEKKVLSEDMMAKLGQMMMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCQ7</accession>
    <name>A0A6A6PCQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Deoxyribonuclease tatD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_332453</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCQ7"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="304" mass="33748" checksum="1FDE2061F9053125" modified="2020-06-17" version="1">MLIGINLSDPVFKGIYHGKQAHDDDFDSVVQRARDVGCEKMMVTGSDLKESEHAVRIAEEHRLCYATVGVHPCAAKQFDTHPGGPSALMSSLRALAQRAALSGHAVAFGEIGLDYDRLFLTPKEQQLKYFEAQLDLALELQLPLFLHMRAACDDFERLLRPVLLRLPSRGLVHSFTGTREEMRRMVDLGLDVGVNGCSLKTEENVEVVKEIPLERLQIETDGPWCEIRPSHASSKYLKDAPEMPKAVKKEKWAPGLMVKGRNEPATIPLVAHVIARIKEIPVGDVCEAAWNNSTKMFGLGETSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCR6</accession>
    <name>A0A6A6PCR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein MSF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCR6"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="21258" checksum="501CB2F864C3E92D" modified="2020-06-17" version="1">MKVFSSETEFEYSWDEVSTANWRKYCPWNEKSTHVIAVDTLSRSIDPDTGVLRTERLITCSQSAPKWLQPFLGGHEMSHVHETSYVNPTARTVTMCSTNLTWSDLLSVRETVTYRPSPGAPHSSTRFEQNAQITALCGGWQKVRNGIEQFSVERFQQNATKGKEGFEMVLEMSRKVFAQEREKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCT7</accession>
    <name>A0A6A6PCT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_329675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCT7"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="25883" checksum="CA548B858F0ACCB0" modified="2020-06-17" version="1">MSATTPEACCTCATLLSARPPAYTYDEKHPYDEKRPDQPPTMTPSRRLPCCRRAICAPCTTANPRFATYCPFCQVSTGPSALPATGLRLPPAYSPPSSLVRARGSRRHVNEGHRFDEDEQPPAYTPRPGAVATPQLDEKASSFADDEPAAPDVLHFLDPERDSVQSLALRYGVPAAALRRANGLFADHLLAARRTALIPGEYYKGGVSLSPRPVDGEEEERRKGCVRRFMVGCKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD34</accession>
    <name>A0A6A6PD34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_3140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD34"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12375" checksum="D8001D4CF28C333D" modified="2020-06-17" version="1">MADVADGMHTQVRYATYHDTRVGLLFLLGHSGYSNSTDTPQQTRTEYPSPITRSNSTPMPFVIPSSMPRSPLEPGIHNLKFCRSATSLSCGKWCRKDSKSGMRLRYCMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDC4</accession>
    <name>A0A6A6PDC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_277101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDC4"/>
    <dbReference type="OrthoDB" id="10257697at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000018">
        <property type="entry name" value="Heme/steroid binding domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="97"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="34011" checksum="0EF57A655DC1E062" modified="2020-06-17" version="1">MASDKSALRSRKSAPPSTSDSTSDSTSKTPPSRADADDDSRNKLGVLDVLRLLGGAALLSCALSWYISNGESLLWGWRPWFVRGQALRSWWRGPVILTDEQLLAYDGSDPAKPIYVGLNGTIYDVSTNPHTYGPGGSYHFFAGRDAARAFITGCFREDLTPDLRGAEEVFVPLDPDSEPDPAASGDPRDSDEAEVETEDGRLVRKGGKAGPVKAELRERAEREWEEARSKVHDAIEGWAKTYRGETGKEYFEVGWIKREKGWLERLEPRGLCEGAKNMRPKRKKEGEKRAKEGNVKGRVRVGEKKGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDI5</accession>
    <name>A0A6A6PDI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aromatic-L-amino-acid decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_277060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDI5"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="505" mass="56468" checksum="0E34B472F262C0E9" modified="2020-06-17" version="1">MDANQFREAAHAAVEDVIKYYESLGERRVVSDVSPGYLRPQLPSGPPQTSEPFTAIQRDIANLIIPGLTHWQSPNFMAYYPANASFPSILGEIYSATFTAPAFNWLASPACTELETVVLDWMCELLGLPECFLSKGEGGGVIQGTASEAIVVAMVAARERYLRNKCDAEGLEGEAREARMSELKSKLVALGSDQAHSSTQKGALIAGTKFQSVPTKMEDNCALRGEEVRRVIKECKEKGLEPYYLTVTMGTTGTCATDRFDEISKVVGERGEEKDIWVHVDAAYAGAALVLDEYKHFTKDWNAFDSFDMNMHKWLLTNFDASCFFVKRRANLTHALSINPAYLRNTFTDSGLVTDYRDWQIPLGRRFRSLKIWFVLRSYGIEGLQAHIRKHVGFGKLFTSLLQSRKDLFSITTEPAFSLNCFTALLDTNEVTKEVYERVNQHGEIFLTSTVVHGVYVIRVVTGSPWTEEKYVRRAFEILVQVAEEVLSGKEDGLGTDLTKTVLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDP2</accession>
    <name>A0A6A6PDP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cupredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_368215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDP2"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF8">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_6G00670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="39166" checksum="387375C2758C34C7" modified="2020-06-17" version="1">MVLLAGQLRRAAIAYLFGAFLGAARGQSFSTVTQSTSITASASLADASSTSSREPVTHTVDVGRYNHEFTPDVTQAEPGDTVEFRFYPTNHSVVRAEYENPCIPYEMTGRGKIGFFSDFKPVDAYLEDPPLWQVLINDTDPIFYYCSAPGSCINYGMVGVINPSANTSLQVQRDLAQDSDFMLQPGEDFPDEATSTPGTADPTASRTGGSSSATGASSASDEDPDDDGDDDDGHGGPHLSAGAIAGIAIGAAAVVAIAALLFYLFGRNRTLAAALEKRDSTTAGARASVGPFGRPPPPGAAAAGPDVHQTPAGAVYVPVATKDAHNHRGSAMSGAPYGHAPPYGYDDGSHGLSPRMGDGAEFFSPSRDRYVRPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE02</accession>
    <name>A0A6A6PE02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE02"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="132" mass="13392" checksum="DE0F32BE3985839B" modified="2020-06-17" version="1">MEARRGSGCEIVAAGLAGPRKPRQGRHDAGRAALAGVGGVQRLRPPPGVRSPRSGMTYATFASGAAAALKPSGWKWPLGRALDPEAARRPPPGPSKGPTGRAWPVQPSLAESASPRASSADAIQRAGALDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEL6</accession>
    <name>A0A6A6PEL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_390218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEL6"/>
    <dbReference type="OrthoDB" id="4676at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03884">
        <property type="entry name" value="M20_bAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="ALLANTOATE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494:SF20">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="215"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2462428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="46043" checksum="D4AF82EE43EF912C" modified="2020-06-17" version="1">MTSLRINGARLNDTLQSTSSQWGAIPDSPGMCRLSLSQADKLARDWLIGECEALGCATKVDQMGNIFAVRPGKAPDRKPIGMGSHMDTQPAGGRYDGILGVQAALEALRTLHERGAETHCPVALIDWTNEEGARFPGAMMASGVWSGRGAAPLAACHATRDSDGVAMRDALARAGYLGETACDWRENGLQAHFELHIEQGPVLEEKGLAVGVVTGVQGMKWFEVRVTGEEGHSGTTPMTKRSDALATASRLITAVNDAARSSPEMPLGGVATVGVIKCDTSSQATIPAGVTFIIDVRARNDDAVSSLSTDIFTRFDSVMRAERDAGSKTAYAVARTWGLPESKFHPDCIAAVRGAAVDEVGAEQVDEMMSRAGHDSAWTSRVVPTGMIFVPSKGGISHNPHEYTSPEHCALGGQVLLQAVLKYDELCSKGTIPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEP6</accession>
    <name>A0A6A6PEP6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Actin, gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_368369</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEP6"/>
    <dbReference type="SMR" id="A0A6A6PEP6"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2462292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="375" mass="41639" checksum="0520E7883A359B80" modified="2020-06-17" version="1">MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAISRVDMAGRDLTDYLMKILAERGYTFSTTAEREIVRDIKEKLCYVALDFEQEIQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVLGLESGGIHVTTFNSIMKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEQ7</accession>
    <name>A0A6A6PEQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">1,3,8-naphthalenetriol reductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_368310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEQ7"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2462209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="268" mass="28319" checksum="D95BCB061EDBC742" modified="2020-06-17" version="1">MVVTVPTASLHDKVALVTGAGRGIGRGCAIELGRRGASVVINYANSKSAADEVCSVIEGFNNGAKAISIRADVSKVPEIERLFTEAKQHFGKIDIVMSNSGTESWDKTDEITPEKFDHVFNLNARAQFFVGQAAYKHVEQGGRLILMSSIAAGLIGVKDHALYNASKMAVIGMVKSFATDFGSRGITVNGVAPGGIKSDMFASNAWHYIPGATPDWSADRIEILMAENCPLGRCATPEDVARVVGFLASEDGGWVNGQVITISGGSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF94</accession>
    <name>A0A6A6PF94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Phytase A</fullName>
            <ecNumber evidence="4">3.1.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Histidine acid phosphatase phyA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Myo-inositol hexakisphosphate phosphohydrolase A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Myo-inositol-hexaphosphate 3-phosphohydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_368171</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,6-trisphosphate + H2O = 1D-myo-inositol 1,2-bisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77131"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2-bisphosphate + H2O = 1D-myo-inositol 2-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84142"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77136"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="4"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF94"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF24">
        <property type="entry name" value="3-PHYTASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="21" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="18">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="123"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="264"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2462033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="58323" checksum="E5DE40BAE25F262E" modified="2020-06-17" version="1">MSEAWDRLRRPKNYTYDTVPQDDEAVDEGPRTPPPHPPRKSLLRRSLIALCSFLIMLAVIAAIVVSIVVGRASSLPLPSVPHTDCDDIEHGYTCRPEISRYWGQYSPYYSVPSGISETLPDTCTVTFAQVLSRHGARDPTAARSIAYRYLIDRLQEDVESFSGKYAFLKVYRYKLGADELSWFGQQELVNSGAKFFRRYSHLAANAAPVLRAAGQHRVVQSAQNFTQGFYAEAARNDWAGPRDDVITVMPEDDSSNNTLSIETCPAFDGGATSSAAQRVWTSIFVPPIRDRLNADMPGAELTDQEVVYLMDLCPFETVSANHNGGPSSPFCDLFAPEEWQAFEHYQSLGKWYGWSWGNDLAPSLGVGFVNELIARLTDSPVHDHTSTNSTLDSDPDAFPVGPDYTLYADFSHDNDIMTIMAALGVYNDTRPLDKTRVQTPDETDGYTASWAVPFASRMYVEKMRCGGEADDGEELVRVLVNDRVIPLRWCRGVDDLGRCRLSNFVEGLAFVRQDGHWDRCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKL6</accession>
    <name>A0A6A6NKL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_408479</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001719">
        <property type="protein sequence ID" value="KAF2452252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKL6"/>
    <dbReference type="OrthoDB" id="2094832at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="39526" checksum="0335D6E88A4EF946" modified="2020-06-17" version="1">MPVAWDKVPLADAQQLQPDRNVAWYKKDLDEVPPAARELLEKYSGIPPDKVKSHVMEIRDKAFAITPFPCIGRFHFLDLSIHTLPAYPEILARARAGQTVLDIGCCFGQDLRKLAFDGAPTTHLHGHDLRPAFWALGHALFRDGPGDTTTAAGTAAADNPHPPRFAATFSAGDFLDPAARPRDRAAAAAGVDVALASSFLHLFGWDGQVEAGVGIAGVVREGGLVVGRQVGNKAAGEYARLGGGGSTWRHNEESFRRLWDVVGERTGSRWEVVEFGIADGAFSVVDGAGWEHPGMVMNTFTGLGSTESETRLGVYIHSRKWRGEIARESASQVAIGMRMEIGAELIEAQEGCDYNGLSGVYVYANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKM7</accession>
    <name>A0A6A6NKM7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/calcium exchanger membrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_262748</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001713">
        <property type="protein sequence ID" value="KAF2452290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKM7"/>
    <dbReference type="OrthoDB" id="10369245at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="167"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="26791" checksum="4EF6598728B1BD5B" modified="2020-06-17" version="1" fragment="single">IIPLAGMLGFVADQLSHYLGEVFGGLLVASFANAPELILSVLALQNRQVDIVEVSLVGSVVSNALLVQGMAFCAACKCPGKMFNKHAAQASLIQFTLCVSALSVVKSVLSINSYTTEGTRRASYGISAILILGYCCYFYLQLKYQSAPQKADEESSRTQPKLAVPVAMILLILLTTLISFHSDFLVSSLSTVLVKIPATFVGLIMIPIIGNAAKHWTALREAYAGQIDLAMGVAFGSAVQVARFLFPVIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKW8</accession>
    <name>A0A6A6NKW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKW8"/>
    <dbReference type="OrthoDB" id="4587838at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="185" mass="21693" checksum="5FACEFBA820C235C" modified="2020-06-17" version="1">MLSPSLRQLQRPKKKSDEEVARKLDEAKTYRALSGGCDYYALAISRIAYIHSKGFLHHNIEPKNFLMGVGKRDNMLYAINFGLAKDRYAGFENYNEREQSWGGDLESLGYVLLYFARVSLPWRGLKVSTGKERNELIKQKKTKFAAYINYTRLLWFKDRPDYACLRQRLRPIFKSHGFKYDNAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLB3</accession>
    <name>A0A6A6NLB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SIT4 phosphatase-associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_375528</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLB3"/>
    <dbReference type="OrthoDB" id="295029at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="987"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="679"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="994"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1022"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1031" mass="111088" checksum="30B60AB216549CF0" modified="2020-06-17" version="1">MFWRFGGYANISTLDSILDKPDVTVEELLDESDLIQELKQQNSKLIEYLRDPKVLERLLQYVVAPPKDPARGNGDGAEPEKEKAGVDDEGDDKGALDSPGAKLEKDEGEKSEKRGIEVLFSKSRGRSKSTSSNKGRATSGGAAADSDESKEDKQRLKYAYVACEILASEVWSISEALLESRDTLREFWKYLKQPPQLDPVQAGYFTKVNEALLDRKTEEMLEFFKSLDGVVEDMLQHVDCPMVMDLLLKIVSLEKAEGGQGIVDWLQSQSLIPILLSYLSPQHPPSVQTSAGDFLKAIITISANATTADQSVIGPNELTRQLVSAPCVRRLISDMLGGGNPLTVGVGIVIEVIRKNNSDYDQENQAGPVPKTSDPIYLGTLLRQFAENVPDFMDLILRGDKVAPITHSDGTISTGRRELKAAFGGKIEPLGFDRFKTCELMAELLHCSNMALLNERGAEADVARRDAERERLKREGKLGVLAQGRGEGGADEDVLSEDVEDSEDEGVGGRRRRASSGSAESREEFSKSVDSQGFTHARFPSATSEEEADEVRKKLAGSAEEEGFERVEGREVFARDEDEGSSEEEDTRGKKGKKDAESPTAAGVTERVGGIELDSDTVMAEDDKQESAGGKSLLSQQLTAKEPKVKKERRQEFEEPSGMSPHPEDKPPPLFAKKGGVVKGERDDRKAEETKKAVGEEEGQEMGTVEATREGPYGVYYEVDIDGTPVVGDMLKIMFVENRVVPTILDFFFRFPWNNFLHNVVYDVVQQVFNGQMDRGFNRGLAIDLFETGAITDRIVEGQRASDRAQDETHMRLGYMGHLTLIAEEVVKFTERQAQAQAAAQHAQATAAAGETSAAASAAAHDASMAAAAATGSSPSHQLLMPQPLAPSVVQKVTSAEWVTYVETTLAETRERDNAILGGVRPDLGVGPRQAVLNAVAGGGGFGGGGGGVSSGNGSIGLDSMELGGGAGAGASGGAYGGGVSGAGLLSGFSHSSDEEDEEMEDGGVEGVGEHVGDADQVGELSFEDVEMEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLL4</accession>
    <name>A0A6A6NLL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_358627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLL4"/>
    <dbReference type="OrthoDB" id="47488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04486">
        <property type="entry name" value="YhcR_OBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42834">
        <property type="entry name" value="ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42834:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025563150" evidence="1">
        <location>
            <begin position="23"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="304"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="611" mass="66167" checksum="C15FFCC339D5BFB4" modified="2020-06-17" version="1">MKSTLWWGSGLHSLLLAVVTSALTIPEINGPSFLSPYSGESVSNVTGIVTAKSEDGIYIRAPRPDNDVRTSNSIYVYSSTVGTNLTVGDLIVLGGEVQEYRSSDDYLYLTEIGSPSDVRVISSGNDVESLVIGHDTLTPPIIQYTSLDDGDVFGVPNAQSRISEENPELQPDRYGLDFWESLSGELVKVQGPNAVSRPNQYGDTWVIGDWQVRGRNLRGSLTIRNKDANPEAIIIGSPLDGSSNPDDTKLGDKLEDITGVLTYAFGFYRILPLTSLNVTSSAQPAQPPATSLESDGTCARVTFAQYNVENLTPDSDHMSGVADHIANFLKNPDVIFLQEVQDNDGATDDGVVDANATLSALSEAIASAGNVTYAYVDIDPENDEDGGEPGGNIRNAYLYNPDHIRLRDPNPGGPDDATEVLPGARLSYNPGRIAPADDAWEDSRKPIVAVFETVTGGHHFFAVNAHFASKGGSSSLHGDPRPPVNGGVDQRTRQARVTGQFIADILAERPRAAVVAAGDFNEFAFVEPMETLRSVSGMRDLDEVAGIAEKERYTYLYDMNSQELDHVYLSHYLAQQSPKFEHIHLNTWVSYDDQVSDHDPSVGRLNICGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN4</accession>
    <name>A0A6A6NLN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_294385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLN4"/>
    <dbReference type="OrthoDB" id="5305647at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF24">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="231" mass="26395" checksum="81CCC5488511E4A1" modified="2020-06-17" version="1">MSPNEEKQLDDSNQPGSPRNRGHSYKREEDPPQNAQGKFLCAQCKNLLFDRRCEWNKHMDKHERPYHCSQKGCEKLQGFTYSGGLLRHEREVHKMHGTNKALFCKFPDCKRSSGVGFTRKENLQEHIRRVHRRPSQAGVDNGDVPSNDDAASPDAAAAVPERKPSPGAEKRKRHSYTGSYGHEDGGSDVDVREEMKRLRRENKALRDDMESFRREIGAIQGKIATLRGDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN7</accession>
    <name>A0A6A6NLN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L32e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_155560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLN7"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="131" mass="14975" checksum="DD1C6A45574947A9" modified="2020-06-17" version="1">MVTAKKHVPIVKKRTKRFERHQSDRFKCVDPSWRKPKGIDNRVRRRFKGQAAMPKIGYGSNKKTRHLMPSGHKAFLVHNVGDVNILLMHNNVYAAEIAHDVSARKRIEIIARAKQLGVKVTNGKARITTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLX0</accession>
    <name>A0A6A6NLX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_294279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLX0"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17060" checksum="4589757CAF3195ED" modified="2020-06-17" version="1">MGHGDMDHGGMDHGGMDMGDDHCSMNMLFTWNTKNLCIVFPQWHVRGALSLVFSLVAVALLTTGYELVRELSRRYEARCAAAVDAGRTSANTRAGQRQVKIVRAAFYAVQVFYSFFIMLLFMTYNGWVMLAVAAGAFIGFLLFGQGSSTKSVACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLZ0</accession>
    <name>A0A6A6NLZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_375689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001718">
        <property type="protein sequence ID" value="KAF2452253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLZ0"/>
    <dbReference type="OrthoDB" id="10449375at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="12152" checksum="34B8EBF54FA89DA6" modified="2020-06-17" version="1" fragment="single">MKEQEELADERHRELQAELQELRAQNEQLKQELHECKQEIKACKDAPAQGAINRSTYAAALTSTRESPQPSQPIPNNTNGPSDTLASLPGFDLDMTEAYGMHMEDASVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMI3</accession>
    <name>A0A6A6NMI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_147717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMI3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025608148" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="17281" checksum="98FA73B690A370BD" modified="2020-06-17" version="1">MHVYSTLRLLLEVLAFCSYVCRGTRVPNHRLRYIRPFTPTLRTRPVPAHPLTQTISRLCHPQMYQLRARMLDEQLTSLCYPLSQCIQTLPSSWGLRCSIKVKKEIAKGESGYLTITISVPRTHSEHLSEIAERDSPRFVCERKRSTKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMV4</accession>
    <name>A0A6A6NMV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_358388</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMV4"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF32">
        <property type="entry name" value="COPPER RESISTANCE P-TYPE ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="563"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="724"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="766"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1126"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1159"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="166"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="98"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="101"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2452674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1198" mass="129019" checksum="ABC19F19AFD3C69B" modified="2020-06-17" version="1">MNARCTRLLVSNLHCRGCAGRIEDLVVNLRPGPISVTCSLESKTVTVSHPPDIEPDAISAALARAGHETVVISQPGAEPSHRHASPLPQFFQHLRNQLRRPSRDKEPKAHPERCELCRAGARDDSTTRGPQAEKDGANSAPAAAEGTSLTALESVQATPATPGEQSRALFSVTGMTCSACVRAITETLEARPYVRRANVVLLASSAVVDFVGDGRAGELADAIEELGYGAVLEEVKPFSQRQAEKARSEPQFWRASFAVEGVTDGACASVVAEALERESWVRKVEVAIVEESVTVEFENKKHISDILRIINSVGDRYHATLIDLAKIGSSDGEPATRTVSVRVNGVSSEESLPQILAALTVLDHPVTVDRQPTLKDPILTVTYTPKAPGFTIRHILAAMETVDQSFKASIYHPPTLEERARAMHARERLLIICRVLLCVLAAIPSFIIGIVFMGLVSSENSIRGYLTTPWANVPRGQWALFIISTPVYFFAADWFHRRALKELFALWRPGSSTPIFRRFYRFGSMNQLMSLGTSIAYFASIAELIIASRKSGAHNSRATVHESFYFDSVVFLTMFLLIGRLIEAWSRAKTADAVASLGQLRPTEAVICDSTRLDKSQPDILRKTPVDEIEAGDVILVPHGASPACDGILLDGQGSFDESSLTGESRLIAKSIGDDVLSGTINQGAPISMRATKIVGSSMLDQIIEVVREGQARRAPVERVGDTVTSYFVPVITAISISTWIIWLALGETGSLPRAWLDVESGSWPYWSLQFSIAVFIIACPCGFGLAAPTAMFVGGGIAAKNGILAKGGGEAFQETSTLDIVVFDKTGTLTEGGKPSVTEWEHVQTSPPTEADSRLVPSLIKGIEEKSSHPIAGAVVRFLDDEDRVNIHLASVDELPGRGMKSLCNSDQYPGKSYMVLVGNETLMSENDIGLDASVVETLESWKVQGKSVVLVAIRITDVEASTLGKWALHVIAAVSDPVRQESGSVVQTLQKQGIDTWMISGDNETTARAVGRMVGIPSDKVIAGVLPEQKAEKIRYLQRSQARLGRHWLSRRQKSTGRATIAMVGDGVNDSPALAVADVGIAIGSGSDVAISSAHFVLMSSDLCAVVVLIQLSRVVFRRIKFNFGWALVYNMMALPIAAGALYSVTSNGSHVRLDPVWASLAMALSSISVVTSSLALKTGLPVVGFRKAGVGPARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMX6</accession>
    <name>A0A6A6NMX6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_367495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMX6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025368204" evidence="4">
        <location>
            <begin position="24"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="279"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="412" mass="45520" checksum="545C9BE9EC7BB277" modified="2020-06-17" version="1">MSSTINFLLLAFLLLATMALLVAFDKVATSLVINVAMVCLWLLVCAFQAIGWLSDVLEDLLTCLLTTRPVNFALTAHIGLLDKFFPAAEYLIVALRGVLSGLWFHLVQHVLAPMGVTEWGLGVCVVGISVFVLGKLIMDELVTLILMHCRGVVRQQMSKTTNAVNKHRRQLENAIDDKIAQATNEHVGVLEALIRAKHEKDFKEYRQQLEASVEAKFAKTVQECRVELERWILARVSTQIKKHRRQLEKTFDTQVDKAVLEQFQKPEESLRSSYTEHPTATTSTSTSTSTSSTSSFGSVSRAESANGAVDTEKNSDIQEINKGAQSPELPRTRAFDFDFGASTTAFGEANTASRLPLRPGAPRHLEDLEIFSNIPEEFGARSKDETSNGPKTPMSRPGYKPNGKKKGKKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN02</accession>
    <name>A0A6A6NN02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_424707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN02"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="185" mass="20233" checksum="6E75CCD7F3972237" modified="2020-06-17" version="1">MLTASCFLGLRYTRPRIYERVQDHPNILRYLGQSPPECTLLRSALLFECHLRGSLTDCLGQLKNLPRGRWLYQAVSAFAYLHFPRVVHAASDLHNSLRDDSEIVLCELAGSGTDGGPLLLTGYGTATRHRECPSGQEDVFALGTVSDALKELEPQPSSALFQAFLGLGVVLAVFVSDMELAAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN18</accession>
    <name>A0A6A6NN18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_375078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN18"/>
    <dbReference type="OrthoDB" id="29221at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="260"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="298" mass="31675" checksum="2475B512DD95F16C" modified="2020-06-17" version="1" fragment="single">MSACVCHDDRRPGSRRDDGRRTTPHDSPLDPGGAPSPPGRRSRESSPSAGASNVPPENENGSPRDDRRSPRSESSQLEDGEILESAGRSSRPTNPKKRKRSRPVANSGKGTAMASQMQMWQRRREELHDGPSKEDSGRCSSAPGSPQAPKEDDDDGFIGRRQGRHCCFLCATAFRDAAHVDDHLRSSKKHAANLRDEALKKKVRAKVAASEAAGAKATAAGKPQLQPRKKQSAAASPPAEPTTPRDAESDGGASAGKYEGMGRGMAMLARMGWKEGAGLGAEGSGMATAIETRMFARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN21</accession>
    <name>A0A6A6NN21_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_146302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN21"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025411245" description="Secreted protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17173" checksum="30422D43479F7016" modified="2020-06-17" version="1">MAFSFFFCSFFFSFFFFGGQFERVETSSGSIFLEVVCLRRNDIPFGMYTMLGLGVRERPNFKPPRSTPVSHAETRTLAARSDCCCREVLVRAAGRDAPRSGLSGAEPRRARRCSAKRRAARPRSAGCNAPLRPTHRYLSIGCIIRTSSSTALTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN52</accession>
    <name>A0A6A6NN52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_357834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN52"/>
    <dbReference type="OrthoDB" id="3797005at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="101" mass="11327" checksum="1EBCE99BF2A12CF2" modified="2020-06-17" version="1">MDQRNCRMLKALDHNNHARTWNAMVRLPETALAPLRNLSTNEPIPGFPQKPDRIGSMSNAAIDLVMRALELSTDHPVAVKRRLLKSYIGLFDPSVPVPSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNJ2</accession>
    <name>A0A6A6NNJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative RNA polymerase I and III transcription factor complex component Tbp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_129240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNJ2"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="26613" checksum="9EAFCF5A4116CF55" modified="2020-06-17" version="1">MESLTTHPSTAQQAKAFTSPASLSFPGGAGDLTPPSSEKDGVQQSNGNGVAPATPAATPAANQGVTGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIRDPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKLGFNAKFTDFKIQNIVGSCDIKFPIRLEGLASRHHNFSSYEPELFPGLIYRMMKPKIVLLIFVSGKIVLTGAKVREEIYQAFELIYPVLSDFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNR8</accession>
    <name>A0A6A6NNR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_356441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNR8"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="78" mass="8556" checksum="901630384EC51C31" modified="2020-06-17" version="1">MLIVEWNKKFRGDGVMVWGADPGRCHTGLGGFQPSAEQVKAMGLKPPEEGAEPVMQILRGEWDGNVGKVISHEGVRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPE9</accession>
    <name>A0A6A6NPE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NCS2</name>
        <name evidence="3" type="synonym">CTU2</name>
        <name evidence="5" type="ORF">BDY21DRAFT_401799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTU2/NCS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPE9"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03054">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="390" mass="41956" checksum="8D55E0A170CE4EB2" modified="2020-06-17" version="1">MASRNHERGVNGLGQQCRRCQANESSIIVRNEALCAECLVKYIQTKVIKRLESFRVRHSAPGRPRKLLLPLSLGISSLTLLHILDGHLRGQRSNTGRTGYALHILHVTTSVQGQWAADPALLKKVKECYPDHVYFAIPLASIFDGDESNGARNTTSAGDHVPSSSSNQNRLDTLLTSLPTPASRSDIISILQTRLIVSFARTAGCESILWGDSTTRLAEKVLASTAKGRGFALPWHICDGPTPYGIDFHYPVRDLLKKELLEHAPLATSSVADIATAPPAPPTPSAAVNVRSSTIDGLVAQYFLKAESDYPSIVSNAVRTAAKLEAAPSDRWGRDGSVCRLCKLPVAEGLFGVTGWGGGRDGGVESRGSEGELCYGCTRSVPRDVVSLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPH5</accession>
    <name>A0A6A6NPH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BNA5</name>
        <name evidence="8" type="ORF">BDY21DRAFT_293199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPH5"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000031">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="7">
        <location>
            <begin position="214"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="165"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="487" mass="53188" checksum="8F9354F66F2DF2CE" modified="2020-06-17" version="1">MSSSEAALEPGGPDVFSQQYAEDKDATDPLRHLRDEFIIPTKADLKRATIDKCESEPESEESIYLCGNSLGLQPRLTSVYVAKHLSTWATKGVFGHFKEHSDSVAPPWLHIADFDAKTESATLVGAKPDEVAVMQTLTANLHFLLASFYRPTKERWKIIIEGKAFPSDHYAALSQLHHHSLPPSALICITPPANPSNSPYLPTSHILSVIEAHASSTAVLLLPGIQYYSGQLLDVAAITAFARARGVAVGWDLAHAAGNVPLRLHDWGVDFAAWCSYKYLNAGPGAMAGLFVHERHGAVDPRRALGYTPRLSGWWGHDKGSRFDMGPAFVPIAGAAGWQVSNPSALDASAVLASLAVFGKTSMDALREKSVRLTGYLEFLLTHRVGGTGNVENEPEPPYEIITPRNPAERGAQLSVRLKEGLLDVVMEILEAEGVVTDERRPDVIRVAPAPLYNTYVDVWRFVKVFKEACRKAKADQNAEKLLKSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ73</accession>
    <name>A0A6A6NQ73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ73"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="8812" checksum="1481181EE9AC56C2" modified="2020-06-17" version="1">MVNKGAADEGTQQVGSGRCEGRRTIWAGPPCVCRIRLPNRAAAAAERLQLPRGSSLAATNAHALVGTRRVGRTWRKSEVGKCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ93</accession>
    <name>A0A6A6NQ93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine kinase 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_354720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ93"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="478"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="72"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="550" mass="60715" checksum="AFE0CCC77C0FA9DE" modified="2020-06-17" version="1">MPFGILEDRHMEHVPGTAVMHDQTDMPEELKGVPSERLKHGSGRFAHIVLIPQPTDDPNDPLNWPTWRKDFILFIVGLSAAVVGAYGPMLGPGFVPIAAELGITINTISEATAWLLLTLGAIVFLINPLAKKFGKRPVYIFAICILFAANVWGALVKDYPSFLASRIVGAIGMAPYEVLVQATISDIYFVHQRATRIAVWNLFLMCGIAGASFISGYIIEDLGYQWTFGVCAIFFGIFMFAIFFFVPETSYRRPDAATVIAQNQANAAREKLGSEGANAGVEKSETYQVETAAVEPPPKTSYWRSLRIFTGSYTNAPLLRIMTRPFVMFLYPAVLWAFLIYGTTITWIVVFSVVNGVLFVAPPYNFTVGEAGLTGLSPFVLTIIAEVVSGPLNDWICVKLTERNRGVYEPEFRLVLMVVVVILGVVGFYGFGATVDAQTHWSGPVLTYGIANMALGFSGPSVFGYVIDSYPNLAEESFVAINARNFLTFGLTYFVNDWLAKQGALEVFSILGSCFLGVCLLTIPLWIFGKRIRSFIARREFLNNYMSDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQJ1</accession>
    <name>A0A6A6NQJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_354775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2454001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQJ1"/>
    <dbReference type="OrthoDB" id="5382272at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.220.10">
        <property type="entry name" value="Ganglioside GM2 activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036846">
        <property type="entry name" value="GM2-AP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025391936" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="4">
        <location>
            <begin position="45"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="22887" checksum="F32C16EA4E22CFFE" modified="2020-06-17" version="1">MFFAFFALTILKASQALWIQGFQKLLVDDGYGSLAGPSIPSSPPFHHCSSVDDDLFFIDWITIFPNPLAVDATFLFQMNGTFARDIEANATVFLNLTWNDSPPQFRNNSSLWGTYDFCSVFGSIEQDSLRDQECPPVKGNALLRKLGFVPFLYPFGNYTLEINGSTKDNNPLFCIQGDFEIKSKFSYLLAGTSIAEQGGATPNTPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQK0</accession>
    <name>A0A6A6NQK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_292579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQK0"/>
    <dbReference type="OrthoDB" id="3933142at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="210" mass="23040" checksum="0EB5AA51262318AD" modified="2020-06-17" version="1" fragment="single">MAPRWPQVNNGPENINEHATYLREACNQLQMVDRGRQNQVPWNIVQPYMESTIALIGKVLRQPAMEAILQHVQDAAKCTENIQRDITTIKNSVGLSTTPPNPANFGGGRPAATTWAQVAAQARDPPPVPPGASATRNQPTVTAYKDRVVTVKLKDHGIARRFRTHPATWIRMQVVTSVHDNAATKSVKIIAAHQLKSGDIQIFTSTTAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQR0</accession>
    <name>A0A6A6NQR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_388023</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQR0"/>
    <dbReference type="OrthoDB" id="6409159at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00917">
        <property type="entry name" value="PG-PI_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.770:FF:000004">
        <property type="entry name" value="Phosphatidylglycerol/phosphatidylinositol transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033917">
        <property type="entry name" value="ML_PG-PI_TP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025534136" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="46"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="18449" checksum="84C3D9BAE9D60251" modified="2020-06-17" version="1">MWLPSTKLAILLVASTCTTAARSTWLGASDQVSLTEDLSVPGDNPLFYCSAPDDDILEIDHVDLSPNPPEAGKTLVISAKGTLSEPIEEGAKVHLQVKYGLITLINQEADLCDQVKNVDLECPLEKGETTLTKEVNLPNEIPPGKYTVLADVFTKDGDKITCLTATVAFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQV5</accession>
    <name>A0A6A6NQV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine-threonine kinase receptor-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_326256</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQV5"/>
    <dbReference type="OrthoDB" id="408728at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF13">
        <property type="entry name" value="SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="207"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="296"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="339"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="381" mass="39118" checksum="8B8082FE70B2EC53" modified="2020-06-17" version="1">MAVETTKVVPLTCHGHSRPVTHLSFSFLDDASSAAAAAENPTYYLISACKDNNPMLRDGVTGDWIGTFIGHKGAVWQARLSSDASLAATGSADFSAKVWDTHSGEGLCTLAHNHIVRAVAFPPSVGRPTTLATGGPEKKLRVFDLSRATAAAAAPSTPNGVTADGSTASSPTAGGGSGGNGAAPAAAGVTNAATDAAVAQSAYEVGAGTHGGTIKSIVWADDNVLVTAADDKKVRWWDLRARRAVADFAVDGTVGSCELNAVESGPPGTLSVAAGKSAYFFDGAAPARLVKKVDCVSGGSGEVASVAMHPGGKKFVTGATGDTWVRVWDFDEEKEIEIGKGHHGPIWSVSFSPDGKIYATGSEDGTIKLWKFTTGPYGLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR21</accession>
    <name>A0A6A6NR21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metallo-dependent phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_354311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR21"/>
    <dbReference type="OrthoDB" id="7722975at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07407">
        <property type="entry name" value="MPP_YHR202W_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053828">
        <property type="entry name" value="Nucleosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014485">
        <property type="entry name" value="Pesterase_C1039"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041823">
        <property type="entry name" value="YHR202W_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF22">
        <property type="entry name" value="ADL392WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21953">
        <property type="entry name" value="NadN_nucleosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017316">
        <property type="entry name" value="Pesterase_C1039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025621887" evidence="1">
        <location>
            <begin position="26"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Putative 5'-nucleotidase C-terminal" evidence="3">
        <location>
            <begin position="429"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="703" mass="78899" checksum="2A2102123A53F446" modified="2020-06-17" version="1">MRAQTSISAAVAVAAAALLPSSILACEVCDGAEEEVAMTRMVRRMQPDAQNATTGPKGPLEWGQINFLQTTDTHGWLEGHLKEQNYGADWGDFVSFVKHMRQKACDLGVDLLVVDTGDLHDGASLSDATDPNGVISNDIFSEINYDLLTIGNHELYETDIAYEHFYNFSKVYGERYVTSNVEIINPETEEYGYVGNPYRYFTTDNGIRVMAFGVLFNFTGNSNVSRVTPAEDLVQQQWFLDAIDYTEPIDMYVLIGHNPVRPSDGISTLDLIFSTIRTIKPDTPIQVLGGHTHIRDFVVFDNKATGIEAGRYCETVGWVAIDGFELDSWSGTECIEGVPTPTRSAVATPFSITTTAVISNTPLPTSDSESSLRYARRYLDWNRLTFAYHAEGSQDSTFDILRGLNVTDEIWDARQDLNLTKLYGCAPQTWCQFCAPPNSSDSIYTLMRTALKQVVVNETRADIARYVIVNTGSIRFDLLKGPFTYDDSFIVSPFDNTFQFIPEVPFEYASQILDILNAGPWQRRRRSVEPQLGTADFAFENYGMPEMERCMDPPLIQERDELSERTVARLNHRVVRRQNTDPVPGYTTVDDFGDDGDDTVHSEIPHFERPIDIQAEGGFPEDGSDPDVVDIIFVDFILDYILDALADAGIEYSEDDADYYLDPSFTSNMYLPEYAKMEWQENMPNCPVGEGIGFNSKKKRARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ4</accession>
    <name>A0A6A6NRQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_353229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="18427" checksum="99305CFB18499438" modified="2020-06-17" version="1">MIVERGKKRERSVLTRLYLTCRAASLRGQSAATEEGPPFAQGPSPPLMTKHHVLGSDPRRQSAKSAPRSFTSLGLRCFLLSRLGMCRYIKTVAGSPSNLANSGGKHNFAFPSYLSPLCDGLHRTLELFSSSRSNWLPARCSGAGVWRKACFRFVIEPSRIRATPHHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSD2</accession>
    <name>A0A6A6NSD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal peptide peptidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_325720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSD2"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="507"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="592"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="656" mass="73108" checksum="DDCF28A5D77ECEDC" modified="2020-06-17" version="1">MAPGVAAEALGWIAYEFARIQPQLPTHLHLVLSALLPIYTGAFASLCRPASAAEPEARGRRVKRDSDNSDDDDDGVVDDDADEQMQKRMEGLSLSDAVMFPVFAGSTLAGLYFLIQWLKDPAILNAILNYYLAVVGVFSVSKFVADTFSFVHELLFPAYYVHDGILFHVNRAERKIEPYSGPVQGSAKRRHSPLPGFLSRVPLPSSVSRLLWSWAIFPEHKLIVRIFLRRVLSVKVRFDCFLVIGALTALTSEFYFTFIDRPWWLTNLLGFSFAYGTMQMLSPTTFGIGSVILCALFFYDIYFVFFTPMMVTVAKSLDIPIKLLFPQPSTGKIASHAMLGLGDVVLPGIMIGLALRFDLFLHYLRRQRRADAPSTLAARPHGLENSSEGSIAIERAKYRPVSGTWGSYFWTRTWLGHLLISEPYPCPDELRVHFPTPYFNAALTGYVVGLIVTLAAMHVSNHPQPALLYLVPGVLLFLYATATLKGELREFWNYTELVEEEIQGSIQMHDPNAGRSKKHAKESHQETGGSSSQKPLVSDAHEALASGSRTGSSSIQRGHSGHPQESKAKPRKKSTREIFAFRVFVRLARQRSTSAEAVNKENGNTQAAGPAEMPKLTENCYVQNQTSELHGKEPRWKSPQKDGVDTEPAGKRQRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSN3</accession>
    <name>A0A6A6NSN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSN3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="144" mass="15111" checksum="6A2EF33E96426274" modified="2020-06-17" version="1">MGAARRPSPPGALPLAVWAPSRLREPMDGSLRALGASARKLGSGSRARSHLVLPQFGIDEALRSTVPFGARPPVPQGGVSLWLESRKQVETTVASLCRIQRPSTKGTPSAPGESAPALARQPRTEPSPKPVSGAGWNIRPDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI7</accession>
    <name>A0A6A6NTI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_98937</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI7"/>
    <dbReference type="OrthoDB" id="2279611at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="24804" checksum="845E2AD5DFBFE022" modified="2020-06-17" version="1">MPNKLMWTFIGVDLLFLAGGCLIIAFAVMSEAEMRATPQLDTVATHVLLEQCPLTAGIVNAIFVFLTFLVSLPALALPQNRGWLRAHGWLVVICAIFTLALGINIWFDTLETRSNIERLWGQESRLSQSLLQQKFDCCGYINSTSPPFIMDNTCSSTLVAAQKQGCVGPFSNFANSYLDLIFTMAFGIVGIDVIMLLCTVMVIKYRGELIRYRHIDEKNGNGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTL2</accession>
    <name>A0A6A6NTL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_95708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTL2"/>
    <dbReference type="OrthoDB" id="5396252at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068:SF1">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="878"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1090" mass="116116" checksum="42A5B5887BA4F63C" modified="2020-06-17" version="1">MLKKLPGISGRRKSAGTNALDEFDQPSGESSSSFRVMTRDEVLHTAAQEAENKKVHRKSLVSGRPFSTPLQQQQQRNSRHAQHSFDEEFGSSNRGSDGSSASRSTGSKGYDTASSMRFSSSSTLPSSADVEAEDNIFKKSHAGHKQSSDHTFSLRGAAKSIGIGRGHWQTGSGASRQELGGSPYDTSNEYSKGGRDRSQTTSSYASTATPPKLGGDIGLGFSDFGNDFGSYFSGMDKRRSAIMEESQTGGPRRSDTEPVRSYQPKPELPQSRSFNTPQPIRIDKSKEIDQSPYSWDSRDSGDGLMSSPRTDSPSLQDKPPPPPPHAALRANSYPTNIPEPPVPAHTERRSGRFGTPKVVGGLQRRSNTSSGEIQDADAELVRRSVNASRAARRSNSPPKEGRPPARPQQSNPVGYSPSDASLTIPSLSSASSSLEVKDKNPYQVRNLTPETPMESRSAVSNNTTPRAAPAQKPMPPLPKSPDAEPVQLFEDSDAALASVAAKYTSSNQNDVTEQPKVMNAAQFERYKKQKEMSGGDSDSENSSEAGSDYDDDDTERDRKQQEARRKQAAHLAVHRQQMRKVVGGSSEEPGPLPDRPGLGSTLSLPAGLSSMGLNDGTGGGKSSDEEDEDIPLGVLQAHGFPGKNRPPSRLPNAPVSWELPGPNGVPPRPATATGGPRSVSGMSVAGGPDRAGGPLPAFARNLPKDVPPFFGAGLVQAPNRESLMYGRNPTGPPPGAMGNDGGLVGVIAQEERARAARRGSPNMQTGQFSMPQQQQQQMPQQQVGGGMGMNGMGMNGMGMIGGGMGMGMGQMGMMGPQMMGQQGMPNFDQQMLFQQQMAQQQQMQQMLQAMAMMTGQQLNPMGMGMGINPQQQNFQGNQSLRPPSMASVATQQRPPRAMSMTSQTPFPMGMGQQQQPMQQPWLTPAAANRSTYAPSVMNLAPPPPPLHGGGYAPSLAPSERSNIGMASRYRPVAQHQPNADTMSTVTSGTAMPGRGSLAAAEEAERPRSGAGGVGGKLRVGIRAKSKSRERKPLQRQSSTEDDDDEGWESMKKKRNATKGKWGSGGAAAASSAEARSASEPSLAALYYDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU05</accession>
    <name>A0A6A6NU05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_289851</name>
        <name evidence="13" type="ORF">BDY21DRAFT_291831</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU05"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000007">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="12">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="10925" checksum="67807E574339C008" modified="2020-06-17" version="1" fragment="single">GKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISAMIYEETRGVLKTFLEGVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU82</accession>
    <name>A0A6A6NU82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_373395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU82"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000010">
        <property type="entry name" value="26S proteasome regulatory subunit RPN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="225"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="425" mass="47544" checksum="7FFC7994CBC653F3" modified="2020-06-17" version="1">MAPAAAEDAKRIAEAQKLSKQQPGKAEAIYQDILSKDPGSGDAGIKNFEVALMSLGQLYRDNHKVDELAELLKTTRTYMSSFAKAKTAKLVRQLLDLFTPIPNTLETQISVTKSCIEWAVSERRGFLRQNLETRLVSLYMQKEAYYDALMLINSLLKELKRLDDKLVLVDVQLLESRVYHALGNVPKGRAALTSARTSAASVYTPPLLQAGLDMQSGMLHAEDGDFNTAFSYFIEAMEGYHSQDEPAKATSALQYMLLCKIMLNLGDDVNSLLTSKQALKYAGKKMDAMKAVARAHTNRSLEEYERALSDYRFELGTDRFIASHLRRLYDSMLEQNLIKVIEPFSRVEIDHIAKMVGLDTQQVERKLSQMILDKVIIGVLDQGAGCLIVYDEAERDQGYDAALETIEKLSNVVDALYTSQASMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU88</accession>
    <name>A0A6A6NU88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_387166</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU88"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="9"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="26236" checksum="71BA116658D4AAB3" modified="2020-06-17" version="1">MSVKRYRKHFIPLESNPDVFTDLIHKLGASPTLGFRDVLTLDEPELLPRPALALILIFPTLEAYESQKEKEEALYEECAGSAREEEVVWFEQTINNACGLYAILHAVCNGDARNFIHTGSFLATLLETCLTPRERALALESSGELESAYATAAKQGDSAVPANAEDEVDFHFVCFAKSSKNSHMYELDGDRKGPVDKGALLGSNDDIFTEGVLGIVREYIQREGGESSNFSLMALVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUR9</accession>
    <name>A0A6A6NUR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_289247</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUR9"/>
    <dbReference type="OrthoDB" id="407390at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF25">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="282"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="380"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2455520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="476" mass="53687" checksum="57A955BAB4A34B6F" modified="2020-06-17" version="1">MAHGRASAHACVRSFQRRCNRSLFTHERQQHAGSRAASIHPGANGAPPYRPSSVLDDWVQREARPISLRQLTFFGRTLTEARLLSSANYVRTELPTRIAHRLRDMQTLPYVVVTNHHISHVYELYYRAFERLRRVPEIRTVDDNDRYCKVIKETLREHLTVIPRLAMGVLEIQGLMKPEETDKFMTTLLRSRISRRVIAEQHLALTETFHSPWYFPDATKLDNEHVDFVGEVFLRCSASEVVQRCAATIRDIVREAYGPAAPVPEIRLEGHLDATFPYILSHLEYIVGELLRNSIQAVIERRRPRGVASPPPPIEVLICETNQHVIIRISDQGGGVPREILPHLWSFSKGPRRQMRLEALNQVPQLAATLQELKALVSGTARHGGGGKRHGGGHGGKHQHQPKKKLPESSLGSLSGRPPDLRLGIGLPMSRIYAEYWAGSLELHSLEGYGVDAFLQIPKLGNKNEQLTTRASMDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV12</accession>
    <name>A0A6A6NV12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV12"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="85" mass="9393" checksum="D37CE86EFEAB0AEC" modified="2020-06-17" version="1">MNETESRAAFSVATFCIGLEFGKGILPRSFQAMLDERGIESGMGFGISNCPDMNEGSRILSFFSSIAETFLFGRRINRWAEKGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV43</accession>
    <name>A0A6A6NV43_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tryptophan synthase beta subunit-like PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV43"/>
    <dbReference type="OrthoDB" id="10059875at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006058">
        <property type="entry name" value="PRK08206.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42937">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42937:SF1">
        <property type="entry name" value="DIAMINOPROPIONATE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="1">
        <location>
            <begin position="28"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="38676" checksum="B09C3E2877D71052" modified="2020-06-17" version="1">MYVNHNARSWRSTSATPTPEVEDFHRLLPHYSETPLVSLDSLANGIGAKHLFVKDESLRFGLPSFKILGASWAVYRAIAKKTGHDIPVSLQQLSESAAKQDVMLVCCSAGNWGRAVARMALYLKIPAVVFVSRYVDQATRNIIAGEGAEVRVVDGGYDASVEEAKTHAEDTGSLLCMDTSWPGYEEIPAWVADGYSTMLAETDRQLHDIVGRPATCVVASVGVGSFAAAVAAHYKQPSTPSTAVIAVEPTGAACLHASLNAGRIVSIETGETIMCGMNCGTVSTIAWPKLRDGVDASVTVTDREAHEDTRLLGRNGVRAGPCGSATLSALRKVVATSALPTALGPEAIVVVFCTEGQRVYLESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVB9</accession>
    <name>A0A6A6NVB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_75415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVB9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="11967" checksum="1A8FCE81C3012087" modified="2020-06-17" version="1">MYLIESRSHAAGIEGLASAVEMCGRDGRASCRNQGALNRLWHPLGLAASERPRRRRATGSFGERHCFELVSRRRFHSRSRLAAPTLPRKLEAEPAGRRARHTGSHPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVF2</accession>
    <name>A0A6A6NVF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_373311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVF2"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="293" mass="32408" checksum="CB08295070D36190" modified="2020-06-17" version="1">MTTSSQPCHFLRIPPELRLYIFYLVLQSQADTETTEMWPPASIPITCNPRNNNYLKTSLPHHWPSIFRYWGSPRMAAALRLNRQLHREATDVLYTRFTLFFAFNMNLTAAEFSSWLAARGPAAARLIRRVCIPVMLDTIEVPEPPPEADASAVAGWASALARHSHELATTVRVALPALRFVALDVGIIGDAFEVSQIQGDEGSAARAAHAVPLVDVLVKLGHVFEGVAKVVFVLSDWTGSPRYQDLIGRAAAIGGWDCMTVNTSSREKVGESRWWIVNKAEGGERGSADRWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVK9</accession>
    <name>A0A6A6NVK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_60141</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVK9"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="48"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="493" mass="54901" checksum="CA981ED02F37551C" modified="2020-06-17" version="1">MSNSPKEDIKVSDFRASSPEPEAGTSEGQHLPTYAHEKALVFRFDFRILPVLAFMYLCNALDKGNLGNAKTDGLEDDLHFRNGDYNMILSIFYVPYVLCAPPIGMLGKKFGPSKVLPIMMFCFGSFTLLGASVQNFAGMMTLRWFLGMAESAFFPLVIYYLTLFYRRGELARRLAIFYAASNIANAFSGLLAFGVFQIESSLPGWRYLFIVEGSVTVAFSLFAFWYLPKSGPEAGFLSDDERRTAYLRIQMDSSSVVNEKFNLREALKVFRMPAAYAWLAIEVCLGVPLQSVSLFLPQIVARLGYNHVKTNLYTVAPNIVGAVVLLILAFASDLTRLRFPFIALGFLLTFVGFIIYLTIDVQAQLNIAYFACFMMTWGTAAPSVLLSTWYNNNVAHEGRRVTLTSVGVPLANLMGIVSSNIFRNKDAPKYIPALATTAAFGGTGAIITLGFGLFMILDNKRRNLKQGVNLTARDVPTERLREGPANDEFRWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVV6</accession>
    <name>A0A6A6NVV6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase family 15 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_349894</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVV6"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000051">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Ktr4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF7">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR018153-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="396" mass="47006" checksum="BEA7E6218D38C124" modified="2020-06-17" version="1">MALPRSMRILAAITLGIFFWLVLQIFRAPAALEGLDNGKLDHMDRDPNLDPTGEPPEPLRRVEGDNYAPDNPNSDRIAATILSLVRNEELKDILQSMRDLERTWNRKFNYPWTFINDVPFTDEFKEKTRAETKAEVRFELVPKEHWDVPSWINDDIFDESVKVLEEQDVQYMAKKSYHQMCRWNSGLFYKHPALKDVRYYWRVEPKVHFFCDIDYDVFRYMHDHNKTYGFTINLYDSPQSVTSLWPETIKFLADHNQYIHPNNAMDWLKDSTRRPDLNKLAHGYSTCHFWSNFEVGDMEFWRGQAYEEYFNHLDRAGGFFYERWGDAPVHSIALGLFEDQSKIHWFRDIGYQHIPFFNCPNSPKCKGCVTGRFTDGEAWLNREDCRPNWFKYVGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWK2</accession>
    <name>A0A6A6NWK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_56718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWK2"/>
    <dbReference type="OrthoDB" id="5376804at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="726" mass="81786" checksum="82DF1F2D63599631" modified="2020-06-17" version="1">MLQPTSTRTFTDSSISSNEDDITLTRNSNSCDSFCDELVVHDLPSAVTATPPKDWPNSATTSTSQEPPPQDLRSSESPSEPVDQKSRRLRRIIRRDGIIRVIIELWGVELFTWGIAAVFMGAVVVGLILMDDKPIRDWPLGISLNAYISVGAKIVTSGLLHSTSESLGQLKWGWFGGSRSRRIGDFELFDNASRGPWGSVLLVALTKGRSIATIGAIITVLSLGLETFIQQVVSVENRTVLQEYGSIARTSFYQRTPVYRQETEFNGTRIMYMNQEMDAILEPFFFGPGIDPVTFGNGTKADMPMFCPTSSCTWEGYESLAVCSTCEDVSEFLYKTCMDVEVDWFLNATEFEEESLPHETRTVCGHFFNGTTDNGTTAYLMSGYAVDPFTGEPGEALAGRNFPMTNLNSRRAYNGGTLRFEDIRNPMMDFLVVSPHNTSIESIYQQTPPGAQECLLYWCVKKFNSSYFYGTYHEEVIDTFHNTTEAPYQWTMEYRPMWPYDSFSNWTVTYDMNITMEPPGSNVSFATSNETAVEIAFVFDLLLPSYTVYENSSVDSRFRFDQLRTPKVRTLDVNPWIHPDNVSIHLEKLSTAMTNVIRSSSNSSDYVWGEAWGDETYFQVDWQWLTLPLVLIVASFGFLVATIFLSLRERNVGVGVWKTSALATLLNGLPGDVQNKINRSASRAHIDPREKARGMNVRLIPNQDGWRMSAQGVSKPKRFFEKIWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWN9</accession>
    <name>A0A6A6NWN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_288889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWN9"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="8"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="73" mass="8259" checksum="199532B25B602815" modified="2020-06-17" version="1" fragment="single">MAAPLSHDPYATLGIDKDAPSSAVKTAYRKLALTCHPDKVLDPQLKAEKTDQFHKIQEAYDILIDDDKRRKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWQ2</accession>
    <name>A0A6A6NWQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiolase-like protein type 1 additional C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_323764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWQ2"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040771">
        <property type="entry name" value="TLP1_add_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF139">
        <property type="entry name" value="THIOLASE-LIKE PROTEIN TYPE 1 ADDITIONAL C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18313">
        <property type="entry name" value="TLP1_add_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase-like protein type 1 additional C-terminal" evidence="4">
        <location>
            <begin position="438"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="536" mass="58207" checksum="86FD1F9E2EB29A55" modified="2020-06-17" version="1">MAGPTLRETPVVIGIGDVKNRSPHASDAREPADLMLQAIQVALADAAASASKPTTTPAGLQAAIDSVDIVRNWTWPYSDLPSLLCEKLGLRDADVKHKFESEHSGDKPAKLFDGAARRVAKGECMLAVVTGAEALASLSAFAAAKKLPPPGWTTPDRSVESVFSPTTRSLRDGIGANHSVGAPIHVYPMYENGFRAHRHQSIEDNWNESAQMYAEYAKIAERNPHAWNYGKPAEAAQSIGTVSKKNRMICFPYPLLMNAFNSVNLSAACVLTSASHARELGIPEDRWIYPLGGAGTQDHIDFWERPNFYSSPAISRSLDAALEASGLDKDQVDLFDFYSCFPIVPKIACQHFNLPVLHPPKPITLLGGLTSFGGAGNNYSMHAITAMIRALRASPNKSARISGLVLANGGNLTYQFAVCFSTKPRMTPDGAAYPEKNPLPPKITDVRVPRVDAHAEGEAVLETYTVEFGRDGSPLRAYVVGRLKSNGHRFVANHGDSSTLQHLISKEVEPIGRSGWVRVDEEDKRKNLFSFEGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWT1</accession>
    <name>A0A6A6NWT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWT1"/>
    <dbReference type="OrthoDB" id="3944675at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025587640" evidence="1">
        <location>
            <begin position="29"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="275" mass="30008" checksum="7AF6EE9C0226E299" modified="2020-06-17" version="1">MSVHPFSGLAMKPFILLLFVAIADVVSSLTDLQVYRREAKPNRETEEEFEQNTVGLQDQGLCRKYLGTTRGLTGLEICEPQCGDLATGGAHSVTCSADTPGNGTPLYTDPEGNQYTIGECICDMPFVEELFQEIVLALPAIGDIGCAILKNALGLVLEYGPLGIPGVGTVISVGMRAAISAAKTFAENGLGSQDFLDWLFPCGNRNLRDGLQKGARLPGRLRRPESRRFSGRVNEGRFSFDGHFSRESHFHEGRRSKLEGHCYYEGDFSPGHFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX78</accession>
    <name>A0A6A6NX78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX78"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="88"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="267" mass="29047" checksum="2D7DCA13A51A5F91" modified="2020-06-17" version="1" fragment="single">MDSGFSPLTGGIVDRAMPSLRVVVFCSATVPKWLEKRIAARFGRDKLIKLASPGLHAVPRRVQLGAVDTEQEPYRGRKDVACADVVWKIGKAATEAEEDVDAGRNRTKRIVVFVNERESAVKVAAFLRSKGVDAVAWTRDARTGDEAAQGKDGSGAAVLEGFVGWAAGDSKHEDESKQLVHKSGARVRLPGVKVLVTTDLGSRGIDTTAVRHVILYDVPQSTVDFIHRLGRTGRMGRRGRGIVLLGKGDRKDVVREVREAMFRGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXD4</accession>
    <name>A0A6A6NXD4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="5">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_49935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="5"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXD4"/>
    <dbReference type="OrthoDB" id="6038816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF11">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025646815" description="AA9 family lytic polysaccharide monooxygenase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="7">
        <location>
            <begin position="19"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="223" mass="23839" checksum="39D3926B62C106D7" modified="2020-06-17" version="1">MKAVTFATAALLAGVTNAHYIFQRLTANGVQGDVYQNIRENTNYNSPVTDLDSNDLRCNVGGESGAGTGTVSVEAGSKVTFTADVAVYHQGPVSFYMTKVDDASKADGSTPWFKIKDIGPTFNGGQAQWDMSTSYDVNIPTCVPDGDYLLRIQQLGIHNPYPAGIPQFYISCAQISVTGGGNAEPSPLVDIPGAFHEDDPGYTANIYNNFNSYEVPGPEVFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF4</accession>
    <name>A0A6A6NXF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_56552</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXF4"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF14">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="12"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="519" mass="57986" checksum="8ABBA8DC12F91C74" modified="2020-06-17" version="1">MGMFQSKYVVLCAFVVRLGGFLFGYDQGVISITLVIDQFLDRFPRVSEDSSGAGFWKGLMTAMIELGAFLGAFNQGWISEKISRRFSIVVAVCIFVVGSVLQTAAQNYAMLIVGRLIGGIGVGMLSMVVPLYIAEVSPPEIRGSLLVLEEFSIVFGIIVAYWITFGTRYISSEWAYRLPFLLQIFPAILLGISVLFLPFSPRWLVSKGRDSEALATLTKLRRVGEDDPRVQAEWFDIRAEVAFHKEVVETTHPSLGVSGHRSRGAAVKLELAAYMDCFRQGYWRRTMVGIMLMFFQQFVGINALIYYSPSLFETMGIDYEMRLVLAGVLNVTQLVGVATSLWTMDKLGRRPLLLFGSAGMTVCHIIIAVLVGLYFDSWGDHKDKGWVSVAFLFAYMLIFGMTWGPVPWAMPSEIFPSSLRAKGVAWSTCSNWLNNFIIGLITPPLIQNTRGFGAYTFFAVWCLVSLLWAYFMVPETKGRSLEDMDQVFGDRAGTGDKIRRKEILNALRVRDARPNNASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXV2</accession>
    <name>A0A6A6NXV2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_55950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXV2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="14894" checksum="43464DB4DD82B5C3" modified="2020-06-17" version="1">MRPRRRPRRALLFAAGLRQSVGLRPLRSSLPWPQPCVYVVVPRAGGPRAGGAALRVSIHGSASPLSQGRGTLPAGSGRAARGGPGPCPQGAGIVASWPPELSRLSFSFSRHHRAASRACMPRLYVVRWRTIHLLHPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXZ0</accession>
    <name>A0A6A6NXZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 19">Mevalonate kinase</fullName>
            <shortName evidence="19">MK</shortName>
            <ecNumber evidence="3 19">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_286933</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="18 19">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 19"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXZ0"/>
    <dbReference type="OrthoDB" id="1652964at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000027">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000003">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 19" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="22" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="22" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="12 19" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16 19" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15 19" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="20">
        <location>
            <begin position="145"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="21">
        <location>
            <begin position="315"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2456665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="459" mass="50185" checksum="BDFE87D4BBFD1A23" modified="2020-06-17" version="1">MSPRRMSTPLMPAFMVSAPGKVIVFGEHAVVHGKTAIAAAISLRSYLHVSFLSKSHRTVSLRFPDIELDHTWNIDDLPWAAFSAPPKKRFYYDLVTSLDPDLVEAMQPHVHEVSPHLPEHARKVHQNSAAAFLYLFLSLGSQKWPACVYTLRSTIPIGAGLGSSASIAVCLSVALLLQIRALSGPHPDQPSEEAALQIERINRWAFVAEMCIHGNPSGVDNTVSSCGKAVLFRRIDYRKPPKVTSLWQFPELPLLLVNTRQSRSTAIEVAKVAALKEDHPVVTNLLLDAINEVTESAHRLIDSPDFSKDNPSQLKVLGELITINHGLLVSLGVSHPKLERIRALIDHAGIGWTKLTGAGGGGCAMTILKPDVRQVALMESLERNLEAEGFELFETTLAGDGVGVLWPAVLHNHSGEEGGEEIDQEKFLNAQGNDGIERLVGVTSDVAGPAREGWRFWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY23</accession>
    <name>A0A6A6NY23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_347694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY23"/>
    <dbReference type="OrthoDB" id="4757095at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7730" evidence="3">
        <location>
            <begin position="154"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="414" mass="47434" checksum="19FA7AA0BA08EF65" modified="2020-06-17" version="1">MDKAHFRVLPSIRRISWQAVARISYQLFFIAACCRGRTKAMTSREERVRRRLVIGALIGFSPLILFCGACYCGTVCAAHVCQACLGKCFPERFKPSSPAAQRKRDKREIERRSRHAPVPLPETRERALSPVGVCQNQRTSKRDRKKPATLPASSQAQSPLFSRLPKEVRLLIYEHALGSRDVWTHVMCKPKGLRHARCFDDEMRIGWQHACWGHCWPDGSFRGPSSRAPGKADRSLVALLQTSRLVYSEAIDILYTSNRFHIRQNRVLVYLSQSILPSRFHAIRHLHLTTVFALLHEQLSQLLRHQVFVDDWWGDWPPDDPCTWTRFCALVGSMRGLRVLRIELTLGLSVREPREVDDDLILFFLRPLTSVAVKDYAVMISAELKPSLLATLGQDVPFRLIGRSGYIQRKTVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY98</accession>
    <name>A0A6A6NY98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Moeb/ThiF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_322860</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HesA/MoeB/ThiF family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY98"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061503">
        <property type="term" value="F:tRNA threonylcarbamoyladenosine dehydratase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061504">
        <property type="term" value="P:cyclic threonylcarbamoyladenosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000125">
        <property type="entry name" value="tRNA threonylcarbamoyladenosine dehydratase 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="13">
        <location>
            <begin position="103"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="519" mass="55688" checksum="D67BB7496537FB69" modified="2020-06-17" version="1">MSSASAPAWRAVHVAVAAAAASGALVAAGILGFQGARRRRRVARVKESIPEAGEGHEALRLTEYGAASDIFHPSKEDQQSAALAARARRGDYDEDLILEQLARNRVFLGDDGLRALRAAFVVVVGCGGVGSHAAAALARSGVGALRLVDFDQVTLSSLNRHAVATLADVGTPKVHALRRRLEQVVPWTRFDCVNDVFRAPTPALLLRPDGSPPSFVVDAIDNIDSKVALLRLCAARNLPVVSSMGAACKSDPTRLHVGDVSATTDDGLALATRRRLRALGVASGVPCVYSSERAGPGKAELLPVPEETAAQGDVEQLAVLPQFRVRILPVLGTMPALFGLAAANHVMLSLARYPHDYRPTKVRPKLYDGIHGALQGLEERCARHARAAEAPDRTADPVVGLRLPVTVGEVGYVVEEVWGGRSVVSGLPTRLVVARWEPPGSERGWLDESVEGQKRSSVRLDELVCFTKEEVARHEKEVLKGAKSAEEVWGPDVAERVGRKMEEEREVRRAMERAAGRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZJ8</accession>
    <name>A0A6A6NZJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_344954</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZJ8"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.830.10:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="594" mass="66676" checksum="9E4513B7B604372B" modified="2020-06-17" version="1">MDVVQAVSGYISKMMSAGDSAAGTPAAKMKILLLDSDTVSIISTATTQSALLNHEVYLTDRIENQNREKMRHLRCLCFIRPSPDSIQALIEELREPKYGEYNIYFSNVVRKSSLERLAEADDHEVVKYIQEYFADFLVINPDLMSLNLGFPHHRIWGPSPDAWNPDSLQRSTEGVLALLLALKKKPLIRYERDSLLAKKLATEVRYHMTQEEQLFDFRRTDTPPILLIVDRREDPVTPLLTQWTYQAMVHELLGINNGRVDLSHVPEVRPEMKEIVLSQDQDPFFKKNMFSNFGDLGQNAKEYVEHFASKQAGSHKLESIADMKRFVEDYPEFRKLSGNVTKHVTLVGELSRRVGEDNLLDVSELEQSLACNENHSNDLKSLQKLIQNPSIPANNKLRLVALYALRYHKSPSSSVPVLLDLLSATTPLPRHRIALIPKLLAYHASLQHAAAGSSVGDALFPSSSIFSGARDRFSRGLKGVENVYTQHSPRLESTLQDLIRGRLREAAYPFLEGSGSTREKPQDIVVFMVGGTTYEEARMIAQVNASSPGIRVVLGGTAVLNSETFLEEVEDAVGGWPEDRAGSAVERLRREVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZQ5</accession>
    <name>A0A6A6NZQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_37487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZQ5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="498" mass="55478" checksum="737064B16F3BD13A" modified="2020-06-17" version="1">MLRESRSRGLRGRGSCRLVSCCEVCCGGRFLRSGIGKEEKIGAKEAGWWGHGVEGHLKGFFSLSFFFGQACLIRFFEKHPWEQRGIGPSGMGDWLGVRNTTEMGQQEGADAVGRWSFYFRRISACPRQQLTQTLVVAAALDSKYKMRFPLPRFGGFLLPCRAYFAAVEVGSRHCRISQHSRCSTGPGPAAYMRDSLLSLLSPLSSSTSLSNSNFSIPSSIHHVPQIRNTLASSFQLSTPGSTTSEGRVAMSSHRRLLLLLVSSTFFRSTHRTHCLLLLARPTHSLTPRNRHAPQPTQPSKPSKPAQRHSTDQHLAELQESTSSHEPATLPPAWPSASAQFLPPASCPGMYYAPARYVIGVRSRYIAHPVACLSFNLKRFRFHHPVARRIAELRDIQSLYKSTKGRSRTSVLFPGHYVLLRGSVAELCFQSGRHTQTRAPYIGKEGKASHGTRSKLERDLVESESVRTSRQTKVRPRHEHSDDDRDVGMSSISQRPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P018</accession>
    <name>A0A6A6P018_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_343608</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P018"/>
    <dbReference type="OrthoDB" id="387657at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000059">
        <property type="entry name" value="Inositol phosphosphingolipids phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF24">
        <property type="entry name" value="PHOSPHODIESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="16" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="15">
        <location>
            <begin position="15"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="348"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="507" mass="55948" checksum="1F938D0128934BC7" modified="2020-06-17" version="1">MPEPGLSPTTLRIVSLNCWGLKYISKVRAPRLREIGRQLAIASPPPDIVGLQECWTQEDYHAIRAETAKVLPYAKFYHSGIFGGGLVILSRWPFEEASMVAYPLNGRPAAFYRGDWFVGKGVACARIRWGKGRRGVVEVFCTHLHAPYEPEPYDSYLCHRTAQAWHISKLVQHARERGHLALALGDFNMRASSLAHDLIAAHTGAVDVWSVLHPDAALGSSVDAIERARGRPVPTAKVARDRDGATCDSVLNTWRWNKGNRQRLKRGEEVHVSEDEPDPKAKRLDYVFVGGPLGGREKAGGSVDEDGVEEEDWTVVDANVGMMMRHPSIKCSLSDHFSVEATLELRPRKQGVAGVEGKNQPSSSSSPADSAIKPNTSPFPLPSLLPSTTYASILTLTRTYTERERRQRRLRLSHCALQLLITISCLVAVWWAPHNGVAFALMFVSSLGMAAGVLDGLMGGLFVGSELRALREFDWEVRTAKEMAERQESAYGEGTRSLMTESGKSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P037</accession>
    <name>A0A6A6P037_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_346180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P037"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18636" checksum="B565EED6029967B7" modified="2020-06-17" version="1">MDATFALTNMCPQVGDGFNRDYWAHFEDFCRRLTARYPSVRIVTGPLYLPKKEGDGKWRVSYEVIGAPPNVAVPTHFYKVIFAEDGVAGGNVALGAFVLPNAAIPNEKPLGDFEVPVEAIERASGLEFASKLPAARRKRLCTETTCSLVVRGYSERQKTLQQQSRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P041</accession>
    <name>A0A6A6P041_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cora family metal ion transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_364070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P041"/>
    <dbReference type="OrthoDB" id="29879at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000008">
        <property type="entry name" value="CorA family metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000027">
        <property type="entry name" value="CorA family metal ion transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF55">
        <property type="entry name" value="MAGNESIUM TRANSPORTER ALR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="257"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="697" mass="78106" checksum="0F87E8D73A8F5C23" modified="2020-06-17" version="1">MSGTPHSEACESRFSTPVSELDDHRNQPVNLPPPEHGYPPGSRRETFSSTANSERPNLVLQVEENLRQGMTSRDFENAITEEPGDRVNEQTIGDTIYNRRGSSATSPIARRNTFRRSRTQQQSQQQPQQNERMPTASRSSSPSAHTISPRNSMEAFADHKRRERAGTLNSVVAPPLSELYLNHTISGGTHQRRPTISENKSPCPTGADSVSTRSSVEDDVCFPQPEHKHDENAIDYDELESYARECRLRPKLDNELRRKPSTVASQQRRVFYDQRPQSSKASIPRFVARSTPTPGGGEDACSVVDEKDPELAAKHADLIDALDRAKSSGDPAPAESTPTMWTFFSADMNNCVFSDTIGGLLMEGETFRDLFELPDQENGEQQPVRGSSAAWWLDLLNPSEDDITAVCRAFGVHPLTREDICTQETREKVELFKRYYFVCFRSFNQDSRTSDEYMEPINVYAVVFRDGLLTFTFCPSPHAANVRKRVGRLRDYVSMSSDWICYALIDDIVDAFQPAIREIEQETDLIEDNVFTARAEDSRQILRQIGDCRKKVMSLMRLIGGKADVIKGFSKRCNTEYEQAPRSHIGVYLSDVQDHVVTMMTNLQHFEKMLSRSHSNYLAQISVDNLAQGNSVNETLGKVTVLATILVPLNLICGLFGMNVNVPGGGAGGLGWFFGILGVIVMFVIICLVVAKKKRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P094</accession>
    <name>A0A6A6P094_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_267512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P094"/>
    <dbReference type="OrthoDB" id="2821191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17969" checksum="C5B69B7A0BD0F199" modified="2020-06-17" version="1" fragment="single">SGDQWGTKSIREVNPAASERTRSWIERSEQNAQWSSDWCRAFVAEASSGVLVAGIVLDSKAPAYVHSVLPEQDESDPFVYLAYLMSNRHAGEERKGAAAALIAFAKDQVHSVGLNRICLDCWRGNDRKLVRYYESQGFKPLEDFTVAEKNDWPGCVLEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Z0</accession>
    <name>A0A6A6P0Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_378828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Z0"/>
    <dbReference type="OrthoDB" id="5424391at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="445" mass="48385" checksum="C101F48A32539877" modified="2020-06-17" version="1">MVLKALRRALHPQLPLSPRQSQQLLAALTSSFRAHLDRHHPAPGARRVADRASAQSSVDRHLASIFAHSRPTPTAARVGSLFELISTPASVDPSARLDALDRKLAALLHALVQGAERPAAPPLREAAASTNAGSAVLSWVRASGLEFSPELISHARLARSLSYFLSAEERYDVLNGWLGSSVSLSSRLTAQAVRQWKIRSLRAFVQAEFDFAGTPSLPSKRPLLADPTGNGLLKAIPVISHAGSLAEVDSHDYRSNTSATNLRHVLQPVLVDLADSISLSLLRVDSVDPALYDDLVSVYASLRQLAISTKIAHASVVIRHPDLNSRDIDLALETLKEMDGLASGSNFKSFGKRGAIKRMVIQLALDAAQELLHRKRDLDAAWVLSYASRAFSDEFGQNEARTEDVGLPLETQSGRSQDYNPVGESPRHARDDDSSVLEMLRFRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Z6</accession>
    <name>A0A6A6P0Z6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl transferase/acyl hydrolase/lysophospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_371686</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Z6"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07216">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF4">
        <property type="entry name" value="SERINE HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="20"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="436"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="496"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="24"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="513"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="657" mass="72209" checksum="91C1A6AD2C731986" modified="2020-06-17" version="1">MDSTGLRRKDTTKGPPLRILSLDGGGVRGYSMLILLQELMHRTFVETEGRAPKRHEIPKPCEHFDLIAGTGTGGLIAIMLGRLRMDIETCKDVYVRMTKRVFETDKTIAGIPYRSTLFKASKLEEAIRDCVREHTITDEEGNDIAASQLNLSSPRSPVTSASSFGGAPVRTMSNASRYSQYGMSPVYRGPSAAAIRWGNPNALLYDTRENRTKCAVTAVYRGTPKNGSSVLLRSYDSRKEPAPEFDCTIWQAGRATSATGLAFKPIQVGQSVFIDEGAGKYNPAPQILDEAVCNEWPGRDVGVFVSIGTGKRPPGTNNQQHLWWEGFVSSGMGDFAEARRRLIAKIEGCEDTHQYMLRDHLSKRHVNPENYYRLNVEVGVGEFGMNEWNRLAEISTNTRMYLARQEVQSINISAAAKIARIHRAKIRWERAQAQGYDPEQFQASGRPLPPIPSQTSPPPPSNPMAVELPAEDVPPSASSPRLRPVSQLLTPSDAASYEHHYNGGYDSHDHAPPHKRAHSAPHHHQHRHADEKYAVVSSDEYPQPVDTAADSAVSSLGPSPRRSAEDARRSGDHPRRSGEHVGSSPPPRPPKTPLPAGENVHAPPPPPPRNHAPPPPPPGNPASHMTRPPKGINVLPYPDSDGPPPMVDRSRKPNMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P135</accession>
    <name>A0A6A6P135_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_272771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P135"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="23551" checksum="9ACC9947C2AF29F4" modified="2020-06-17" version="1" fragment="single">TSGFKPQQKLPKNWPPNLTYLTSPIYSASITPELRASLTTTTTSPSASPPSSNPTPTNPITTHPPSPFRLPAGPSPHVRIAPITTPAHPAHAQHGLFAATHLPPSSPIVLYLGVVHDSSSSDPTSSYDLSLDRDRGLGVDARRCGNEARFVNDYRGVRPLGPNAEFRDVWVEVGRGRRERMVGVFVVGVGRMGRGKRGIAKGEEVVVSYGKGFWKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P137</accession>
    <name>A0A6A6P137_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_27830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5427134at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1314"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1371" mass="144479" checksum="9D84136B56B44A45" modified="2020-06-17" version="1">MAAYAQHNRNHNHQNRVNPNGSAASNNVSDGNDNRDNAHRRARRAPATSPQTSSHLPPYIPPLPVRASQDELPDTDERASASVSASSSAVGAGAQPRYQQQQRSRNYTPQLGGWGRGNGGAGGAGGSRQQQQMPQQSPPRPHPRGPCHYRDLKLGAEAPCCGCRRFWLDEERAAVRSPSLASFTAGKHRIGGCGAAAGGGASGARPSPVSPARESPWCMCGHHGCFHDFAEPGGAAAAVAGASEARVGEGETQISGGGASRGPPVAAALQRGGETVPVLVQGQGGLRYQLVAGSHPVSLKRLRDTAPSSSANLGSPDHQPRPRAETGSQGIGNSSPDGGAAYPGNGPDLPNPSQVSTSCLPPIPSQCQLHSDDMRPFSQGPSSRPRGGQHQLHSGPSGLGLVMQPSMPSLGSFNGQFHDALSTNCSGAADIPTDWQSGSTRRNTPESSGQQPSLREGFTDNQATRSRVVDKPPLDVNNVQPGLGLENLLLSATELATPSNGNTPALGAAQENALDEGKSLVDALSREVEAASLEAAAQRDDNEDQRGKEHPSSLSQRKLELVRRDGTSKTWSVDASTLTQLLSHLSSLQNFVSQAYVPSDLGLTVKSLAQRLELLENTSFSHVPIEEVEEKFELVDGRLVELETRVTEHDKLHAAKEAEQDGRDHAGRQSRHLRDAGEEGASFASNVSRQSNSSALVEAALHKLETDSRLGDIDKRLNSIETTAVPTFDRPWEVEVIVLPWGRNLRGIWFSPDEPAASGSSHPTSTLTTQDSGEWTQAHSLQSSSALLGDSRFGWSAQAIHNWADRTEEWLSPKACGTNALVYKRLRSRGFVKTVTLRSGGARDTARTVCSAFGELLSKLSSPQPPGMDRDFHQSIPQQEGHLSYDTSENADGAETSAYLGLQSPFIPLRKVHRSSRLLFLTPSEMLSSAFWTASFLASGVMMRAAHGQKRLFVTHRDGYLQPLSSEAKTRARADGWTWQALRELDRAYPPPSAGGSNVANSFDSRDSGVPEADAKEECWAYHPNLDPAPPRDGTSSFASSCSVPFGSTRSHPSHHIDPSSAGKGHLGIGNASSSAQEEARRRPPITPVSEAPPLYHRRTVSVPLTADKASPMAAGSAYGKRPIASFEAGNNKGSGSGSGSGSGSGSGFGPSSKLAHHSSASTIRIAKRRRLTRSPDAARDSASTAVLGASTASASHTGGERVEPAATGDDDDPGSSVADATVRLWGVTPRRSKEPQSPLFFGRSGGGGGAASGSGSGSAAAAAGASASAAKRGVTPVAYATPYSGPVFAGKFAKSESEEDDKGGFFERAGSGEGEEEEGGDDEMEEAWEGLQEGAEEDEEEEDSDDDDVVVGFDDDESNESGFVDEMDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P173</accession>
    <name>A0A6A6P173_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_371326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P173"/>
    <dbReference type="OrthoDB" id="2915840at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="645" mass="70504" checksum="8786AF0BADD6419F" modified="2020-06-17" version="1">MEEADLTVIGAGWSGLAAAKTYMEFHGSAKVVVLDNASSIGGVWAKERLFPCLWSNNLFGTYCYSDYPMDGAKYGVSPGQHIPGTVVHAYLNDYAAHFGVDRVTRLCSSVVAVEEAAEKNSWDLTVRRDDDDIEKGEYKLRSKKLIIATGLTSEPFLPALPGADSFGKPMLHSRDFGSHSSELTSSKAKSVAVFGGGKSAWDHAYGCATAPNGPEEVHMIIRSSGHGPCFMSYPFVTPLRKQLEKLVFTRCISWMSPCAWGEQTGYAGLIRRALHGTFMGRWVVDAFWKILEADVLHANGYDKHPEMAKLRPKAKPFWCGTFVSMLNYPTDFFELVRNGKIKVHVADITRISPGTLHLSDGTTVPVDALVCATGWKHKPPINFVPASLGPELGMPHRTDQYASLASSPISPGSAAAASPTSPSSPSSARLDPLADAAVLRRFPRLAQPPSSQTSVPHLKDADRADQAERLDRGFALYRFMAPPARLRSRNIGFAGMLKSFGTPIVAQTQALWLTLLFDGRLEIPGEQSRSAAGPPSGGEELDKAEGGLGEGRQIASEKSAAEWEAALNSRFMKWRAPAGFGAYFPDMVFEILPYIDRLMEDLGLEKRRKKGVLKEVFEPYSVNDYVGLNEEWKRVHGNEAIAKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1K0</accession>
    <name>A0A6A6P1K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosidase 2 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_343116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1K0"/>
    <dbReference type="OrthoDB" id="28322at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039794">
        <property type="entry name" value="Gtb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036607">
        <property type="entry name" value="PRKCSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028146">
        <property type="entry name" value="PRKCSH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630:SF1">
        <property type="entry name" value="GLUCOSIDASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630">
        <property type="entry name" value="N-LINKED OLIGOSACCHARIDE PROCESSING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12999">
        <property type="entry name" value="PRKCSH-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13015">
        <property type="entry name" value="PRKCSH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025669834" description="Glucosidase 2 subunit beta" evidence="7">
        <location>
            <begin position="22"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="8">
        <location>
            <begin position="440"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="567" mass="63195" checksum="04477BB5B71C5449" modified="2020-06-17" version="1">MRRLALDALLVLGSSVPLAIAASDSARPRGIGPEFAKFYKSSPEPFPCIFNPSIQIDASRINDDYCDCPDGSDEPGTAACGHISRLSPATPYGTGTDGVNATAALPGFYCKNKGHRPGYVPFTAVNDGVCDYEACCDGSDEWGGVGGIKCPDRCGEIGKEWRRQDELRQKALGAARQKRKELVDEAGRVKKEVEDRIETLKTQIEGAEMSVSSLEKELRETERRERGKMVRSPGEKKGGKWSVLAGLAKERMGELKDNLQRVRGERDLWKERVKELEDVLSKFKEEYNPNFNDEGVKRAVRSWEDYAAREKGPAEDAAHDRDLAEMLKSDEENGIKWAEWEETSSEDDIDVLYQIENYLPAPIRQWVDQKLRDLRLMLMENGILADNSSGAGESQAVKDAKTQLKAAEKDLEKIRKELKGHQEDLDKDYGPDGVFRAIKGQCLSQDSGEYTYELCWMEKATQKPKKGGAQTNMGKFARIETVTVDEDLPADGRGLGSGKRYALKMENGQHCWNGPNRSTTVILACAEKDEIWKITEEEKCVYRMEVGTPAVCGSDPKGNLDRSKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1T0</accession>
    <name>A0A6A6P1T0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative nonsense-mediated mRNA decay protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_284808</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1T0"/>
    <dbReference type="OrthoDB" id="760868at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000244">
        <property type="entry name" value="Nonsense-mediated mRNA decay protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="899"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="914"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1054" mass="120144" checksum="430B22526D7F359B" modified="2020-06-17" version="1">MDVAGVRDRIKGTLDANADIRRQAEIDLKYAEDQRGFLDALLNVLEAEQEPGVRLSTVVYLKNRINKGWAPAEEFSVAKPIPEEEKAALRGRLIPVLAASTSQIRAQLIPMLQKILSYDFPSRWPDYLDGTLNLLNAGDASTVFAGLHCLLALCRVYRFKANENRADFDKIVAVAFPQLLNIGNRCVAEENIEAGEMLRTVMKAYKHAIYFELPVPLRDQQTMVGWCTLFLNVVAKDAPPSAMPEDLDEREKNHWWKAKKWAYANLNRLFVRYGNPQSLSKGSGDEYSSIAKNFIDNFAPEILKSYLRQVEKWVAKTQWMSKPALSYTLAFLDECVKPKSMWNHLKPHMETLISHLVFPIMCQSDEDIELFEDDPQEYLHRKLNFYEEVSAPDVAATNFLVTLTKSRRKQTFTVLNFVNSIVNKYEAAPDDEKSPREKEGALRMIGTLAPVILGKKSPIADSVEYFFVRHVFPEFRSPHGFLRARACDTLEKFEQLEKFAFKDSNNLIVIYRNVLESMADPDLPVRVEAALALQPLIRHEPIRIAMQQNIPQIMQQLLKLANEVDVDALANVMEDFVEVFAPELTPFAVALSEQLRDTYLRIVRELLERNRENKDDDEPYGDFLDDKSITALGVLQTIGTLILTLESTPDVLLHLETILMPVIQITLENKLFDLYNEVFEIVDSCTFAAKSISPTMWHAFELIHRTFKSGAELYLEDMLPALENFVTYGTNMLIHNTTYLDAVVDMVRTIFQDDKVGGVDRICGCKLAETTMLTLRGHIDNYVPEFVQLAMVALTNDDPKVKSYRIHLMEMVINAIYYNPRLTLHVLEANGWTNKFFSLWFSNMDSFTRVHDKKLAIAAITSLLTLQASDVPPSVQQGWPRLLQGIVRLFQTLPAAMKNREEATKEEDFSISNEYDDEEEEDWAGEGDWNDEGEEAEDVKDESAAYLDFLNEEAQKFNTAAATADDDDELEEESILETPLDKVEPYQMFKQALMQLQQEQPQLYEDLTKNLNPEERQVVEAAVHQADVIAMQIQQAQAQAQQAQQQANGNSIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1X6</accession>
    <name>A0A6A6P1X6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_285123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1X6"/>
    <dbReference type="OrthoDB" id="5399569at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3660.10:FF:000002">
        <property type="entry name" value="Prephenate dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3660.10:FF:000004">
        <property type="entry name" value="Prephenate dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3660.10">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046825">
        <property type="entry name" value="PDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050812">
        <property type="entry name" value="Preph/Arog_dehydrog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363:SF0">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20463">
        <property type="entry name" value="PDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="376" mass="42237" checksum="CAA4D9F59EC02470" modified="2020-06-17" version="1" fragment="single">NVQILANGHLVSRCSDFIIYSVEAKNIDAVVAEFGPSTKLGAIVGGQTSCKAPEITAFERHLPNDVDIVSCHSLHGPGVDPKGQPLVLIKHRASQGSFDFVEKILSCLGSKHVYLTAEAHDRITADTQAVTHAAFLSMGVAWAANNQFPWEIPRYLGGIENVKINITLRIYSNKWHVYAGLAILNPAAKKQIKQYAESVTELFKLMLAGQREELTARIMAARKSIFDPGRGHDLLLKDDVLDRFSLGDIPPQRVKNNHLSLLAMADCWYKLGIDPYEHMICETPLFRLWLGAVQYLFQDSELLDEVIDTAVEDKSFRADDLEFTFAARDWSERVSLGNMDGYRERFEQIQRYFAPRFPEATRLGNEMIKTILEKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P275</accession>
    <name>A0A6A6P275_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mss4-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_274757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P275"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF30">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03180)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="39051" checksum="EF8C52D1E6932611" modified="2020-06-17" version="1" fragment="single">DSTTTVRGSCLCRRTSFTIPLPTSYVPQAKHLCHCNVCRRTSGTLFTSYLTLPSDPSTTPPSGLDLALLTPYTSSTLTRYFCPTCGTHVAVRGHTDGALLVCAGTLERTQGVVKIVGHEWIEDSRDGGGSVWLPSLGPDRVPAERWLRDPGTSPQAPLEWRDSVAGPGAARTDEHLPEDTLPARCHCGGVQFRIKRPSERSARSAAAAAAPFPDLLVPYHSGASAANPDSEAWWLTGPDLSRFLAGTCACRSCRLALGFDVAAWAFVPAADIVLPDGGAFRREFGAVKTYGSSEGVTRGFCGTCGAGVYWSGDWREELVDVAVGLLDAPEGVRAEDWLGWERGRVSFGEEGRERDVVEALERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2H2</accession>
    <name>A0A6A6P2H2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="3 14">2.7.7.79</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_341710</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="16">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="3 14"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2H2"/>
    <dbReference type="OrthoDB" id="62560at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3000:FF:000001">
        <property type="entry name" value="tRNA(His) guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF6">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028980">
        <property type="entry name" value="tRNAHis_guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 14 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="18">
        <location>
            <begin position="15"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1 C-terminal" evidence="19">
        <location>
            <begin position="149"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="38"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR028980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2458166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="34406" checksum="B121E37CBE6BA1F2" modified="2020-06-17" version="1">MPRIAFRYRMANSKYEYVKAFERSNYLLPNSWIVVRLDGRGFHKFSAKHRFEKPNDKRALDLMNAAAIGVMKELPDLILGYGVSDEFSFVFHKDCSLFERRESKLSTTVVSTFTSYYVHLWSTFFPDTPLSPPLPSFDGRAVVYPSVSNLRDYISWRQVDCHINNLYNTTFWALIQHGGMDGKEAEKALMGTVSSDKNEILFSRFGINYNNEPEMFKKGSVVFREYEQVLGPMSASRSSTPATEGTGQAEPLSKTAAERERKTRARARIAVEHIDVIKDDFWVRRPWILSGKAGKLPKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K0</accession>
    <name>A0A6A6P2K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_284438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04043">
        <property type="entry name" value="C2_Munc13_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052811">
        <property type="entry name" value="Glucose_resp_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010439">
        <property type="entry name" value="MUN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014770">
        <property type="entry name" value="Munc13_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263">
        <property type="entry name" value="ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263:SF1">
        <property type="entry name" value="C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06292">
        <property type="entry name" value="MUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51258">
        <property type="entry name" value="MHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD1" evidence="3">
        <location>
            <begin position="700"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="905"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="domain" description="MHD2" evidence="4">
        <location>
            <begin position="1119"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1372" mass="158031" checksum="A0D7F61AEBD16FDD" modified="2020-06-17" version="1">MEYSRSRPQNRRFNSIQNEVRHRRPGSSLRRRPATAQDAYTYCLRVAFLSYLLQPRAKRLQHVPASGSGSRAVQRSSTSMNDLMKDFSLIRDSKSTRFPHGFMSVLDKRITGVLYGKERMPEYADSLVKRTFAVFLNEFKEERFRKSMEKDRRVEDLLLIFFSNATKELQKGKPPDDDGWKLMVDRHVALFIRLISSILKDHDWAKDRPELSSRLQTMEKKLLMHDQDLAAQSQRNGGSGGSTIEVEVPRSYEVKDMPLAQVVGRIFKVSYDDLQSDINKNKSVWTEKAAFQDLKSYQVNLSLHNKKTLTTDDFDSDEAFENWKKGETSDLSQMMLAIVQSNPELAKSAPGGSLPQFKPANGPSVDAGYAEIAKRMPDLAENGSSYVIDQPVDMSGYGDDARDSDDDVPYVFIPPDPRSYYRAALREALTHDLHDQELQPSEATADTPAIKLLSKQSAELLNEVALRWRVPQFSRMVLFLDVVREKFLSQEIPLETLDEAFEFLKQPPVEPKKGRSSLIVQSSLFDRTKWTVADYALNQHILSTLHDALLRELFELMMHCYENKPPSLGPVMYILNNHIYDDPIFPQKPEDLDQFSAELQRALRERAMEKYREFLAEKIPDRKEEWQFFHVIELGKSVLKIANSIQKRYRKNPEVMGVNPLTMLLEEIMPSYAQDARELVKRIMITQEELEKEIPIPDGFELYSELVQFRKVFAQSLPNHRFDFPVEEILADFVWRWIGAMESNVTGWVEGAVRLDEFKVRTEHPENIPTDDERHSVSIVDIFRSINQSIEQIFQLNWDNDLQYAKFMTAISKIVGIALARYCELVEQKFAKEMDRLTPEQEAASRQTRQEKWVQLAKDAWTNKERIEPFQFLPESLVKLNNIEYAMQQLDKLEREINVDACADVLQRNQTPLNQRPHKINNYVFTIKIIEAEDLKACDINGLSDPYVVLGDEYQKRLAKTRVIYSSLNPRWDETIDITTQGPLNVIATIWDWDALGDHDCVGRASLKLDPSHFRDYMPREYWLDLDTQGRLLLRVSMEGERDDIQFYFGKAFRTLKRTERDMTRKITDKLSAYIHHCLSYRALRSLLNRGISINSVSSWIQRSKPVPTSQGPTQAEITNALKPLFTYFDENFAIMKETLTDSAMVMVMTRLWKEALVTIESLLVPPLSDKLSQQRQLSQQELDIVFKWLQLLFDFFHAVDEDTGTANGVPVDILKSPKYHELQNLNFFYFESTENLIRTSEAMAAAAAARQHDQASRLNRVSAPPSMGGHGFGGAAGLLGMPRRHKTIMLSRNLGTMKKAKEEKRKEAQAEPSDDIILRILRMRPEAERYLKDRSRQKERLAAAAAAELIVRQSLNQGGPSGRMIGTLPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K4</accession>
    <name>A0A6A6P2K4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_285383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2K4"/>
    <dbReference type="OrthoDB" id="4096at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="345"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="976" mass="107231" checksum="8CF7C9D67FA54E72" modified="2020-06-17" version="1">MGARKRKREATDLPEIAEAQKLKRAQRDARLSATITLAHTGTSSEVVVHSNGTPKVKKSKKSKTSGKKEKKNNKESWTISSAFGGRFLDIDPIFTPDERHLMLATANAVHIYSTPSSLRVSSLPMSISGTISACAISASDSKILYVGTSSGRIYEWDWTKGATVGFWEIGVPIGGLATASADGSVDTVYVLERGESCRITAHRLRRGEGASKNEVNVILATRESIHSFVVLGNGEYLVAVSANELHVSRVRNYSAILLREHKANCWTSKSSEGITAMDARLRSPPKSSKSKGSQEDPSLDIATGVVSGAIFFYEDILSKMNGLVSRKKEKERRRIQGSLLAPRIMHWHREAVGAVRWSKDGNYLMSGGRETVLQQWQLETGKRQDLPHLTTAIDGLVVSPSGTRYALRLADNSVIVLSTSELAATSYIAGIQARTFARRNHFLPRVETVDTLGKRKQPFHPSYTRTPSTLHPLRPKELLLAVPATQSRFDEPGMFASMPYLQTFDIVQERHLSRQALTRNNATIVATGPEKNRLVEPDLTLLKVSEDGMWLATVEEWMPPAPDIDYLARDDNTVRSEQVKRREVYLKFWHWDTKHENWTLETRIDAPHRLPGRQGAGRIFDLAANPSEPGFATIGEDYSVRIWRPKTRIRDGTIVRGTNAECLVTWSLRRAVELEHEIEPSDEADDVSLVEFPVTGRLAFSKDGSVIAAAQSFRQEGIRLVHLINATEGTIALSRADLFSSPLSGIGILGSHLIVLSKTLVVWDMVANEVKYGFALDLTSSIPQAEDFTQLTVNESGNTFAISLPAPPRGHEDGVQLPLTDGVISSLRADVFIFSPSSPAAVNHREVRSLVTSLLAVPGWDQYVILDAAAQIRVLGPARSSSTINVAPKSTLALRGTEALGFLQTASNGDFLLANSAKENGVNGKWDEEEIDGADRPVVRSQTLEDFFQGPSHALPPVKDLFDGLFGLYTGKKVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3A3</accession>
    <name>A0A6A6P3A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidase signature domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_283823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3A3"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058329">
        <property type="entry name" value="Arp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26053">
        <property type="entry name" value="DUF8016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025446270" evidence="1">
        <location>
            <begin position="21"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Scytalone dehydratase-like protein Arp1 N-terminal" evidence="3">
        <location>
            <begin position="55"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="194"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="631" mass="68485" checksum="01A5012ABFC46245" modified="2020-06-17" version="1">MKRTAHFLLGLATIFKATRATLYTAGITMMLSEVPYFVAPESVGSVSIQTFNFSGSGAAGLVPVTVITTLQSFSTEDLSSVALDFGNRDDVFQQAFLEYAIVQYNGSSQPQLGNTTLSSGAVPYDISRTNYRQIPNGPYFASASGLLYKAYRLYSDFEGAFTETAIEKSNGTFAVLPAGVPGQSLSIAVPSRLYYTRTEEQPLAGIRLGVKDIFDIAGLKTGNGNRAWYHLYPAATRTSAVVQNLLNAGAVVVGKMKTSQFANGEHGGDWVDYHQPFNPRGDGYQDSSESSSGPGVGAGAYPWLDLALGSDTGGSVRWPAAVQGVYGNRPSHGLAPMADAMSLAPQLDTAGLLARDPAIWTAAAKAMYGSNITISSAYPVNIKTVGFPTEAREPGDQLLMSWLSNATDFINATALPFDIRARWNSTRPAGTPPLDDMFNETYAIFVSQEQTRRLRDPFYADYAMAHDGRLPFVDPVPLARWRYGDSQPPRLEEAEANKTAFMEFFSSEVLRPSPDTCSDSLVFYVNSRVPTYRYEHRDPPRPPFGFSETMLSVFSEAPDVVVPIGEAEYYSSVTNHTEKLPVTVSIMAANGCDGMIFSLIEDLCRAGILQGSQTGMSQVDSGEVLFKRNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4P2</accession>
    <name>A0A6A6P4P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_341348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4P2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025402130" description="Endonuclease/exonuclease/phosphatase domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21689" checksum="A18495FC275566F1" modified="2020-06-17" version="1">MGEGVRHEAQAAILRPRLLVLLLRPRLPLALVLLRPGRRAVELPQRLEGDAQRHPAGWADTDDLLHVIGNPDNYLTRPTTFRRRTNATDHFPVVIAAGRPFFAPTIPHTTGRAAFLGRRRGHARKTSVRIRGGRFQAKRSLAGQGRRSPARGRRPSKRKREIQKAPGGGRAGPGKERPCSLRAFVWATGSRTLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4U7</accession>
    <name>A0A6A6P4U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_212339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4U7"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="167"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="589"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="759" mass="85953" checksum="74A9930D048F0E6E" modified="2020-06-17" version="1">MSLQLFCNRTDGSKFFSRTTLFVIIYGPMEIFDDVGEYCRQHDAYLQDPIGCDRDVPYRNPHRLDGLDENASTTYQLIAQKGVKEEVVREQVDILAGLEFDEDLPEAEAPAALWTQLYPHQKQALAFMQKRERSWDFKSLRRDLWGIDQDRLGAITFVNNITLDTQYEQPPDFRGGILADQMGLGKSLTIISLIASDFDVEDVGPGSPFPKRVSESDAEDQNSVRATLLVVPPSLLQSWETQLRTHVRRKTLRWFRHHETSKIQNASELRRYEIVMTTFPTISSEFRKRNFADSILFKTRWHRIVLDEAHCIRNFKTTMAKAVCELSARARWALTGTPLQNRLADFASLLRFLRVYPYDDPKMFQIDIINVLKSQGEDIAVGRVKKLIKFIMIRRTQSAIKLPKKTDQVVKLHFTPSELSRYKQAESPIAAMIDDALNSTAQQSGIFIHALARINALRKFCNIGSTASLKEVTSPMFQQPQNLQADISTAQERYDNLVSLGQSSCVVCSSNLEASNVEGLCVGTQSGQAYLTSCMVLLCEACYTEGKESVCSCESPTTCVPEAVITNRALSVPASPASEIFFQDGFPTKIKALGEDLKSSLDEKSVVFSSWTTTLDFVRKMLDKERIPYVQVDGRVPPRKRIAAFDEFRNRQNIKVVLLTIACGAEGLDLTAASRVYLLEPQWNPSVEEQALARIHRLGQKRTVTTIRFAMKDSIEDHVLGIQDRKKHLADLLLSQSQNSTSQQEIAREKLQRLRSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P564</accession>
    <name>A0A6A6P564_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cx9C motif-containing protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_339262</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CMC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P564"/>
    <dbReference type="OrthoDB" id="13601at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000008">
        <property type="entry name" value="Cx9C motif-containing protein 4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027179">
        <property type="entry name" value="CMC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590:SF0">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08991">
        <property type="entry name" value="CMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627179-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="78" mass="8730" checksum="251A35C3A123388E" modified="2020-06-17" version="1">MGLKEDLSYDPPCHPRACAIQNCLVKSNYKEEKCQGHIDALYECCNAFYKEKGDDASTSSCPKASLLRLKMKQRAEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5P4</accession>
    <name>A0A6A6P5P4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">3' exoribonuclease family, domain 1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_257377</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5P4"/>
    <dbReference type="OrthoDB" id="2504340at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF2">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT MTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="10">
        <location>
            <begin position="46"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="392" mass="38824" checksum="10FCD552F0CE066D" modified="2020-06-17" version="1" fragment="single">MADRRRVNAPAGGTAPPIFASTLPGAQTREQLQSHKPRRTRGVDEPRKIFLQTGLTPSASGSAYLELQQPPAAAPSDAPPSLIPAPSTLKLSCTVHGPRPLPRSAPFSPALVLAAHVSFAPFAQRNARAYGPGASAAAAPGAAAGGPAPAPLRRGLDARERDLGAHLEAALRGAVLGARWPKSGCDVAVEVLEAEEGGWWADAALPPPPGASSAAAAAGSAGLAAAWGSLSVLAGCITVASAALADAGIDCLGLVAGGVAALVPPEPPSTSSSSSAATATTTPATAAAPRGAKGGVAATRLGGRPAAPVAILDPCPAEHAAVLAAAVVGYIPERDELTALWFRGSTEGAEGGEEEVELVERAALAATAVHGVLVEAVREGAEAKFGVMRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5P7</accession>
    <name>A0A6A6P5P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_188711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5P7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="57" mass="6252" checksum="64C8C39406EA92A0" modified="2020-06-17" version="1">MWQLVGCARNESHPERGARRPSPPLSPPHGVFVRARLSRRAPPEQIGIARVGRVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5R0</accession>
    <name>A0A6A6P5R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5R0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="104" mass="10993" checksum="2DB76A50C1EFFD5F" modified="2020-06-17" version="1">MVGAFRSFCLSVSLARGMGAVAGRQRGGGRRTWSAARPPVVVACGCAVVDASWLGRPRAPLGPRPPRRADQSADLVSRAGRSPRRSRPIGGLAVRPWEEGSCVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6A5</accession>
    <name>A0A6A6P6A5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_282306</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6A5"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000011">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF15">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="40"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="493" mass="53988" checksum="E1C4131089667440" modified="2020-06-17" version="1">MSSDEIPPVTEWPPWSEARDGGDPRLVNVNAPYDKGDLCWMLVATALCWQITPAIGFLYAGMHRRRHALTMIFQSLFCASAVGIQFWIYGYSLYEAPTTNPILGDMSKAVLHDVVAYPSLANSDIPDISYAAFGFTFVTATAMILAGAMLERGRLWPSMLFLLCWTTFVYYFLAYWEWNPSGWLYNLGVYDFAGSGPVHIASGFGALAWSLMLGKRLDPKGESLHSKIPHFRGHNPFLVGLGTILIWLGWFAFNGASTANLTIRSVYVVVNTNLAACGGGIAWVLAEYIFTKKFSIIGFCSGIISGLVGITPAAGYVPVETSALVGFLTSCCCFFAMKYKYLINIDEGLDIFAIHGVGGVVGDIMTGFFAASTIPALDGVSGDSYDGGWWDHNWKQMGYQLAAAVTCAAWSFFISCLLLFVIGKIPGMHLRASEEDELNGLDFKYLNDVEEQILSLDLSSYGVMTPASRMQHPQAQSESSKEQVQPDAAQKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6A8</accession>
    <name>A0A6A6P6A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PAP2 superfamily-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_378096</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6A8"/>
    <dbReference type="OrthoDB" id="301434at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03388">
        <property type="entry name" value="PAP2_SPPase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="10">
        <location>
            <begin position="122"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="484"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="500"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="678" mass="71983" checksum="39F448C1736FA7C2" modified="2020-06-17" version="1">MAQLDAVAAGREPTAAATGAAPAPAKRVDAMGAKPGVQPGAVIDAGMRHKDHYESRLPRWRYTLRQWLIPIVRAETPYLAYMQAKLRSPALDSYFALAANLGTHTAFMVTLPVLFWCGHSGYGRAQVHMLALGVFWSGFVKDMLCLPRPLSPPLQRITMSGSAALEYGFPSTHSTNAVSVALYALWLLQSTYPSDIHHPLDSTAAAEPSSFVPLALQFLCYFYAASIIIGRLYCGMHGFFDVAVGSALGAAIAYVEWQSAARFDGWMSGPQAGLAPIIFIILAVLLLVRAHPEPADDCPCFDDSVAFAGVVIGLEIGEFRIAGWEFRNAGGRMAAAPELLSAAAAKAVGAVADVDGDAGAVGKEAAALLLVQWGKALVRIVLGVAIIFTWRGVMKPALLKALPPLFRVIEHLGVDLPRKFFLKASQYTSVPPLRRDDNVIPSASEIPSLLTQTFGHPRRPRAVSVGPQSAADAYETLAYRQQRRRRESVGSIDRPVSPVVGGGGGGNGGGGGGGGASVATGRAGGGKEGAIKHFEEMMGEGEVVMSPVSPAGRTAAAVGVDWSGGRGKADVRSGSEGVDGEAAGLERGDTVGVMKEVSAFPKFEDGGFETGGLDGAGEGQEREGEEEVEKEDREIFLRLVKPRVRYDVEVVTKLIIYSGIAWLAVEFNPYLFHVLELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T5</accession>
    <name>A0A6A6P6T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WLM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_413610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T5"/>
    <dbReference type="OrthoDB" id="261960at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WLM" evidence="7">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="411" mass="45697" checksum="F3FDAF8B4D5F7E20" modified="2020-06-17" version="1">MRELDPHFGAYEHLPNLKNPDNALQVLRKVASIVKPIMRKRLWRVGILCEFLPQDPSLQGLNVNKTERICLRLRYPGDPTQFKPLESVVDTLLHELCHIVIGPHNAQFQVLWDELRAEHRDLLFKGYTGEGFLSEGHRLGGRLSKRLPVHEMRRQARAAAEKRAVHNRGSGQKLGGAPVLRGADMRAVIAEAVARRNGIESSPSGKYKGGCASGTKEAARLAEQAKRNGFRTKAEEDDANDAAIAQALIELMEEDETRKIEEREAERDGIEAKMAQPSSSRTMPPPVPLESKPTQPSRAPNPPPTRDTQRQPQSTRPIMAPAAAAPTIWTCMICTLENPQDALECDACGTDRATSVPSEVLDTWSKADSTSRRPEKPKQTEKIGWNCRKCGAFMENQWWTCSACGMMKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Z8</accession>
    <name>A0A6A6P6Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_362294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Z8"/>
    <dbReference type="OrthoDB" id="5354458at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056687">
        <property type="entry name" value="DUF7785"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057199">
        <property type="entry name" value="DUF7877"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25009">
        <property type="entry name" value="DUF7785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25289">
        <property type="entry name" value="DUF7877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7877" evidence="3">
        <location>
            <begin position="66"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7785" evidence="2">
        <location>
            <begin position="516"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="900"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="694"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="749"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="838"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="901"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="944"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="966" mass="102759" checksum="F852CFF8D6109C65" modified="2020-06-17" version="1">MAAITANGAAMPPAAQENATPLAAPATTPATAKRKRSESIDDAKANGASPPHSGSEGAVMPNNTSFQSLLADIILVLKSYDIKPSILDHTIPAVKDRSPSGEPSAKRKKLPQQAGNTSISQRARGQEYTSLDELLQDVEAVASQILAPIKAKESSPTGTGQILPLVQAETELLAGVLGFQDVLKDIIERESSNAKPNQDGNGAGKQRSKNQGRPDMNGVGEVVIKPAEEDDASQERRTVLTIFANAGHPRQLFSSFQQPVRVPAKNTVGHMDTSVEVLLPLREELLHQSFQTTKIVPLASEEAPTDKKKHLTFGEVFAPPPNLPSLNPPKPAKQSVTRGNVISFVQNGPAIKSTRHHTYFGQPLEAGKWLGYGGVEPVQEPTTPGERRKQRDRALSMGEANPPMSAATKASIFQAKEDALFRSAYSGFAPSGDNSNAIVPEETKSRIWWQKSGEQQFLDTTVIDPALLEGEQNGTTVESETDLDEEEKMFAKAVEEYEPEPLKIAQPLDPEEAAKEKEIEELLDEVSEALETIYSMQRIRTSSIASNSRTPVGQSSSLTGLTGSPTTPSQAETDIYEMLKSQLSILISMLPPYAVAKLNGDKLERLNLSQKVVTRTPNYHGVMEEDQISRMAKQSALSAAAGSSASVPPRMGAGPGPAGAPHQYPTLAGQYGARPVSTPAHSTTQQVPPHLRGPQPQSYYPQQQAPNVPRSNNASYARPASGSGGATHPQAYQASPMNYQQQRPGVGGHPTPHYQTPQQQYHGHQHRPPHPPSSAGYPSHHQQVQQHYNHPASAYGARPASQQYASNGAPVASALSPSPQPPRPRTVSPLKPATTATAGSAQPSASGYAQGGGGQARSMYFPPGQQTAAVAAEGSAAAVPTSTPTPTLTTEHQLLRERQRAQQLAAQPQARVAAQQQVGAGPRAMGASRQGQQQQQGGAERRTGGAGPGVGGGVNGSTENWVRFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P797</accession>
    <name>A0A6A6P797_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_180271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P797"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14131">
        <property type="entry name" value="PKc_Mps1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027084">
        <property type="entry name" value="Mps1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="442"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="382"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="798" mass="86426" checksum="0EBD7BD77A156077" modified="2020-06-17" version="1">MVFGSSISSNYMAAASPTPLPAGYGSRLMRQPSRNHQQQQGLNLPTRPHHHQHHHLSRGSSSSRTGSPLSSLAHSNGFAAGQSGIDQLNIGAGDSSEDDEPAPAPQLSRYAEALLAAEQQNINSGIGAGGSAAGLGLGGRPGSSSGPETDAARWSPSHQPAQHASRKLRVYRTASAAAVSTTGAGNAAREGSARAESQEPQYHSSQPNPHQYQHHHHSGSNTPVHGGQEMITPFPHRSVRVRPTGLMKGPPIRGKQRRTPQSDPDKGGGIDGGSAGMNQGAGDGGNVGSGRRDDAGASVLGGHDAEAKEQPAHNAQAPAQGTDVAALDQENAPASIMKAQPHPLSGTTLKEDQQPDSMMKPMKIDEPAQQKRAVVRIRDDHQHQQHKPLAELAVNTPRRAPPPAPAPPPKMSMLEAATSAAGASAAKTKRRRHHMAVNGKNYSLMGRIGKGGSSEVYRVMAENGRAFALKRVKLDGADEAAVRGYKGEIDLLNDLKDVDRVVRLYDFEVDEEKNSLGVLMELGESDLAKLLRTKLESERPMLDLSFTRYYWKEMLECVASVHEHDIVHSDLKPANFLMVQGCLKLIDFGIASAIDTDITLNVHRDSHVGTPNYMSPESLEDTNRHVAAASNGGALPQQLPKMMKLGKPSDVWSLGCILYQMTYGRPPFAHIPNQISRVMAIMNRNHVITFPERGVGDVRVPGCLRRTLRRCLQRDPQARPTVHQLLSAGDEFLYPDQFEAGEDGDEVLRINKEVLGQMFSRIVERCRDEKRPPPSEHEIHVQYPASFYAKIKELMEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7R0</accession>
    <name>A0A6A6P7R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HECT-like ubiquitin-conjugating enzyme-binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_407525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7R0"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019193">
        <property type="entry name" value="UBQ-conj_enz_E2-bd_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31531:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31531">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09814">
        <property type="entry name" value="HECT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="519" mass="55551" checksum="CE409D28A30ED7D9" modified="2020-06-17" version="1">MAASPRQTPAPRPEPDAPPPDRSIAIYAEHLLHTRTISVHAAFAPLAAAPPALGAALAPDRLALLVRRGDQRAALALAAPVAAPAPAPAGPLDLPLPRGAARAGAFALRLRVGAAAAGVAAEDARENVVPWSGAALAAAAGGGEEGAGRDVAACVRCGGCRGGVLRAEKARAWRDLPREDWAEMMEFWHCHKPGGGGEGEGGEAKGYAAGGRVRALEGVVGVAKAYFLVEEEACVNVELPIVLFVQGGEKEVDACYMPDGCILGRFALVRTPDSPAFHHGTRKVQEPATSVGRLVCASCGGTLGSVDVRAEGWRIYKWNLELYDTPDRRKDVPWHHFHPVSKWIVSELLAISESQGVRKFIVSVDEDDVRSKKSEDNEDTGDGTDDVDSKGDDNDKHSPLLLWLFTPDMYYSLSKPFTSPTRAAKIFWKVHEQGHGPAALGENSDEPSSASPKPSSAPLLSSSSLSTEELVFPERLFSRLRPVLEEGTRKLPEMARKFGEWNVALVERFTNKDCDFYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P877</accession>
    <name>A0A6A6P877_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_334707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P877"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090173">
        <property type="term" value="P:regulation of synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013940">
        <property type="entry name" value="Spo22/ZIP4/TEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08631">
        <property type="entry name" value="SPO22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="33398" checksum="CBAD7A1520BDE1A2" modified="2020-06-17" version="1">MATQSTSKLKADRERKLRSVITFASSLEQRIRVDPADAILLSDIQDHLKPLPLEPSAEIAPKRDQLERQGTTLWNLSTRLHRQASLDNGHSNSKLVCILRAFACMILESARPQRTTPALAGTIKLQKVALKAARSCIDQTQLELGIKVLERAAIHVEELEKLSQNEGFLDDDERVCIRLRVEYFMLRTLLHWKQQRLDLANHFFNQSGVAEYTLDGETAEMFADILLEIGQDQFRSKAFDAAVQWLERAHDLIDRQDRDDLSPDAADLHMCISSYFSMFRHFNTANNCFDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8A3</accession>
    <name>A0A6A6P8A3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_384483</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8A3"/>
    <dbReference type="OrthoDB" id="5589195at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042281">
        <property type="term" value="F:dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF1">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="585" mass="65463" checksum="AED0A0C2D01B26D2" modified="2020-06-17" version="1">MAPPSSHKPRRRRKHDDQPHFPLVSFLRPAKGESQWIVLPLILMAAGLFRWATAMWDYSGFQSPPMHGDFEAQRHWMEITTHLPITQWYFHDLEWWGLDYPPLTAYHSWLLGKVGAIINPSWFALYTSRGLDDPDLKVFMRATAFISEYLIYVPAVVIFLRRYSLQQGVNSWESSIALLAILMQPATMLIDHGHFQYNTVMLGLVVGSVSSMLARRALWGSVFFVGALGFKQMALFYAPAIFAYLLGVCLFPRPDILRLIKIGLVTILSFTALFAPLLLGATYHSYVSAPTSITSLPAPPLLSSLPFNPKPDAWYYPLLLQLAQSVHRIFPFARGLFEDKVANLWCALHHSIHKLSPRYSSAVLQRMALLATSTLITPPCMTLFLRPSRRLLPWALAATAWAFFLASFQVHEKNVILPLLPMSLLLGGEGGLAPPVRAWVGLANILGAWTMFPLLRRDGLAVPYAVLTGLWGWLLGLPPWSWECYRKSESKEASASAASPGAEVGWVTTALHAGLYAAMLGWHVLEACVEPPQGKPDLWIVLNVLVGTAGFGLCYLWCLWGLLVRSGLFEGWKDTGNQKEKEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P992</accession>
    <name>A0A6A6P992_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P992"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="419" mass="42996" checksum="746A96DD572A515F" modified="2020-06-17" version="1">MWNAVHDHRAGAGAHIGGSSSSSNQATTGTSTSGPLALRYQTKLVRRTLGPHAQARAPSTLSRRVSAANAPSRPHPPPQPLQPPGYATTHADLAARRADHAAFAAAHRAAESALDAAAARRAAALARVLRAEARAETRAFAAEAALRAAAARGRGPRAAWAAWRLAVGLGAVHEAAARDRRRGGAAGAGAGWRAWTARGGALAKATAACGALGLGLGLPLAGAGLVALGRLCGALWAALVLAPLRAAVLARPAAGLVVAALAVAAWRRGPRAADALADALAAARRRAVAPGADVPRRAPVERRAGPAHRCVAAVRDAVLVALASQERFRAQRLLRIWAWRVGVLGMAALVLGAAWRYPGVKYPVDGVGMEVARGNGTALWTEAGVRREGVARGWWESSSHVRRGSDNDATDTDGGEGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAU5</accession>
    <name>A0A6A6PAU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_360905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAU5"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="177" mass="20004" checksum="E7AE8D9D0A1D3296" modified="2020-06-17" version="1">MSGNDGERHLALDDPDVYVFYRYHPSLAAAVVFIVAFFLLTLAYCYPVVRRRMWYLTPFLVGGICEILGYVGRSLSSHYQWQLGLPPLYAASIYMILGRLIRVLEASKYAIVKPRLITKVFVFGDVVSLLCQCGVGEKIIVVGLSVQLAWFGFFTITGPRFHFLYGKTPEAEETHIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAZ8</accession>
    <name>A0A6A6PAZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polyubiquitin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_361519</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAZ8"/>
    <dbReference type="SMR" id="A0A6A6PAZ8"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000004">
        <property type="entry name" value="Polyubiquitin Ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="229"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="305" mass="34301" checksum="F42BBF708CA6276A" modified="2020-06-17" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB66</accession>
    <name>A0A6A6PB66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerophosphoryl diester phosphodiesterase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_278973</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB66"/>
    <dbReference type="OrthoDB" id="197419at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047389">
        <property type="term" value="F:glycerophosphocholine phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08606">
        <property type="entry name" value="GDPD_YPL110cp_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14484">
        <property type="entry name" value="SPX_GDE1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="461"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="532"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="7">
        <location>
            <begin position="813"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="589"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="897"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="912"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="943"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1231" mass="134668" checksum="7F95B5B4A7C2D5B3" modified="2020-06-17" version="1">MKFGHNLPRNEVPEWAANYINYKGLKKLIKSAAEVVNRGGSVDLAEFYYSLDRNIEDVDGFYNKKYSEVARRLKLLHDRYGRSINIPEGLDKDEAEDLMGALLELRGQLRKLQWYGEVNRRGFVKITKKLDKKIPALCAQQRYLALKVYPKAFATNTKLSHDMKNINDWLSALGEAKTFDDTGSVHSTASLRTVSSKAVLNVPSSLLDGIEQSIRSDDAPMLTQLLNEANSDEDAVRTSYQKFLLNLLQRSISCRAKNCIKNLLPLIVSLDEEDDLNKRNCIHRLVIAIGRSKIYEAAQQDKQNTTSTLQVPSEPINFLSPAESPVLVPRPCTTTEQESIKLLSKNDGSVRLLSFLLDNLGPEQRAALTARDSYGRLPLHYAAQYGFVAICEVIIKHMQDWGQFDVAEGIDAESWQDLEGFAPLHLSVIGGYPRTTKALLDAENWQGNTDAKQAARKSVSKSGAVLALATKSNFVPIVKLLVEAGVDINYIDERGETALHVAARFGHAECAKALIDGSPTQKAQVDVPEKTFAWTPLFIASVDGHLAVVELLIQAGAELECVDLSGWTPKEHAALRGHMEIWRRLAEVTSPPDAPPAPPEVALARSSSPPSASSIDERRSNNVKEGGTSIRSYESVKTFGHRYLTNETMVLVSLGSMDQRKNVQTVKLDDIPLADAHATQLDTALSVVVSASGASGEATVIDLPVQENISTDPITFMTKDAGKVKLLFDIVPTYAGANDRIVGRGVALLSSVKPSVGSKRISLQGDVSVPIMAANTLDVIGSVNFNFLVITPFQHPNMSITEQHTYWKSITSTMVIGHRGLGKNMSTRKSLQLGENTIQSFIAAANLGAQYVEFDVQLTKDHVPVIYHDFLVSETGIDAPVHTLTLEQFLHMSDSQVPLPRHHQGKAMGAGDAKDTTDTRSEQRRETREARRRRAYSVGASEDDVRGSDRSERMKHTRDFKQKGYKANSRGHFIQAPFTTLEEMFTALPANIGFNVEMKYPMLHESEEHEMDTYAVELNSFVDTVLAKVYDLGQGRNVIFSSFNPDICLLLSFKQPSIPILFLTDAGTCPVGDIRASSLQEAIRFASRWNLLGIVSHAEPLVACPRLVKVVKESGLVCVSYGTLNNDPGNVQRQVKEGIDAVIVDSVLAIRKGLQGSNATLAPAAALQDAADKAAGRVEKVEDAQGGGGEIVSKGSVVEVGNLHEVVGDVNGVPIYKRGSGGVAVNGAVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBB8</accession>
    <name>A0A6A6PBB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_369202</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BCD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBB8"/>
    <dbReference type="OrthoDB" id="272357at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23023">
        <property type="entry name" value="zf-HIT_BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057721">
        <property type="entry name" value="BCD1_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25790">
        <property type="entry name" value="BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="184"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="406" mass="45853" checksum="751A267FE78F3C7F" modified="2020-06-17" version="1">MAEQRLLSELCSICNSNAPKYRCPRDAVRTCSMACHRRHKQWAQCSGERDPAAYVKKSELATPAGIDRDFNFLTGIERAIERREREAEEREESLRGGRQVRAGFAPVPGSKYWRRLKDAGVVVDRAPKGMSRQRQNRTRYLNRSQCICWTIEWVHPDQSKTIDEIKDTTPLSDEYDALVKRMEKKRKREDEAVKKESTVVSPTPETSKQVKADSSQKELDKTLDQNSKAQSTFIPATRSTSETELQNVANLDGQSNPDGNIQTDTANDAQPSADFGAQTMSAEIKTESIGSTQQYHFYLVKPHTATAKHVLIPLPRQGTLDKCLRHQVVLEFPTIQVLRESPDRIPEAFMLEAEYVGKEKEDETEFKQLVSGVAVPSTDEVPDDGKVDDRKIIEVLQQDLSNSASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBR6</accession>
    <name>A0A6A6PBR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PHD-zinc-finger like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_331976</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBR6"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15670">
        <property type="entry name" value="ePHD_BRPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000007">
        <property type="entry name" value="Bromodomain containing 1, isoform CRA_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="189"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="243"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="154"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="717"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="793"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="929"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="741"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="832"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="958"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="970" mass="106233" checksum="EB9370869562479F" modified="2020-06-17" version="1">MLNGLGSPPAPRIVPLPAHNPKERLNLPKPSFREVDTFKAYEQDQSVQINYVDRTMASVGYQESDIFIRPERTLIRMADGSIEEDLDLGLLKSDADGHGGSAIGRVEYDMDEQDERWLEAYNFQRKEEQAEPIKPAIFEITMTQIEREWHALEKKIPKPNPKPPQTHRPRSSSAAAVNGEPAAPGEEQDSKCAICDDGDCENTNAIVFCDGCDTAVHQECYGVPFIPEGQWLCRKCQLIGRGTPTCIFCPNIDGAFKQTNTNRWAHLLCAVWIPEVSLGNQTFMEPVMEVEKVPKQRWKLTCYICKQKMGACIQCGNKNCFTAFHVTCARRAKLFLKMKSSHGGSTIMDASALKAFCDKHVPPDWRKEYNVELATSEAKRFYRQTMRGRRWADSQQSALAMTSSQPQNSIEIDDMMLLEESGRKRKMPAIPKNVWRLPSGAPIVPHAVFHNVENSLVRFSIRKRKEYVYEACKYWTLKREARRGAALLKRLQLQMDSFSSMEITRRNFVGMGAAGRPRLQRRIQFAETLQDDMAQILVLCEKVKERETLKLQDAECLKSIIDTVYFPVPPLLWPVLEKAQNLDSKGVFATGFKSVQTKLEERFYTTVPAFAADMGSVFISVLGLPLANESMDANQQLNGAIVKNAGLTQEQKDKKKLAKRIIKAIQGSLEEAYRKEVELTGKPLQRELCDLDAMLEHSIRVQQEVGRVVITGADADGSDEELTRKGSGAVGAETAAASSEMDVDADGEEEEVRNGPKGVSNGNGANGIHHQEADNKASIPIPKEEKDAAIKPAPAGLSVPDIAMPDADDDSGVGAEGPVNGSNGEGAPAPSNGVNGPQSRASEQPKDPVSLSEGGVPWYMAPFDPSGTTVHDEVWTGREVVRGLSEELSELDDDEVNGLVDVDADMQDAGGTAATAGAGSGIAALPNGADGGGAANGVEGAQRAGGDGLLKPVAAAGPRKKTKRRRAAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCB6</accession>
    <name>A0A6A6PCB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCB6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="32878" checksum="23836E9182DEB575" modified="2020-06-17" version="1">MKVQRLELHVILYFGGQNWNRDMLVPYAKHVLSPLEGALRKVHRATLYNFRQDQFGDTPFPRSDNWPDDNSYGLPLPFDWPPAQIASDHVSRQLQFRFVAYQNVDREVNSAEWQDYVRNWSASVCSSEDPDPPNPLEDVYDRLVGLVAKLNHLRPKSVATIAERGIYSPLHLARLARNARDFDAFSEQRQQILETYVAEAASAIDSLWSLRHDHAQMKNDTFLLLGYPVTSDDADPPFPPPTPGAYNGENAETSTMAQASQSPSDELDPELARPPNEMEVDTATGPNGFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCP9</accession>
    <name>A0A6A6PCP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_91942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCP9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="250" mass="27748" checksum="1ADE20FC0CF71431" modified="2020-06-17" version="1">MFWTWGASVCKRRAACSKLLASCFTAVRLGCSVLSVRAARSLPAPGIRLPQPRLRGHPSWNARIWAGRKPHPKASPYFQFYLPILLSKRHEQSHQTSQYVLSGPTCHHLSRRAEARRDGRTPHVPPQIVERPNPRISQRKQEAYFPIRQRGAPSARADCEKGCKPRGCSAFPRSPELPLALPCRTAGSELASQNMRAAVVGCRRCWRALRVAVMCVLLVSAGPASIGVAARTLCEQWPGEGAERISWQLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDQ5</accession>
    <name>A0A6A6PDQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_313022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDQ5"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901">
        <property type="entry name" value="2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901:SF38">
        <property type="entry name" value="PSEUDOURIDINE-5'-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="280" mass="31619" checksum="9853837184D088AB" modified="2020-06-17" version="1">MEVQLPPIRACIFDVDGLLINSEDIYTEIYNNILREYGKPNYPWSIKALQQSRGTPGTRRLLDWAQLPLSIEEFGNKVSAQYDLFKKSQPLPGVVKHVRILSQETNPHMHMALASSAGRKNFDVKTSHLPEIASAFPENRRVFGDDEDMKGKQKKPNPDIFLLALDKINLSLQPGETAVAQNECLVFEDSIAGVEAGRRAGMRVIWVPHPCLRQVCRGWENDVLRGIAEARGFDGHPREDTLGGLESRYDNRFVSSDGFGELLPTLVDFPYNRYGISVWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDY4</accession>
    <name>A0A6A6PDY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_8460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDY4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="21757" checksum="FF87624AFF3DA813" modified="2020-06-17" version="1">MYGCGHGAATRGLAQKACARLTCADGGRRWTAALYLPTVYLFSRRILERRRKEIVGEPKDFGARISCATRPRFSRSWGRTSSGLGRPASFGLPHGVSATGGGDEETWRDQKVENPERGQGEVASRASLRRKSRTRLHAAMPSSGPIGVTRSPITIPLPSRSSPKPNGRWADNSHFHRPMSCRGRGTVAPGSLLGGGALAHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE20</accession>
    <name>A0A6A6PE20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_368148</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE20"/>
    <dbReference type="OrthoDB" id="429626at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2462007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="339" mass="38281" checksum="E0E06E32D561236C" modified="2020-06-17" version="1">MPEEGVPLSPPAHLLTSPEIFYLSSLFVSEGVSKIRLTGGEPTVRRDIVDLMKSIGSLRSKGLRELCLTTNGISLHRKLDAMVEAGLSGVNLSLDTLDPFQFQIMTRRNGHDAVMKSINHILEMNEAGANIKLKINCVVMRNINEREILPFVELGREKDIETRFIEYMPFDGNKWSENKMVNYQEMLDMIRERYPGVQKIKGHKNDTSKSYQIPGFVGKIGFITSMTDHFCGTCNRLRITSDGNLKVCLHGNAEVSLRDMLREENGGQPINEEAFQAIKQLQVDRQEGLLQDDGPDRWSKREQSLLNIIGQAVKRKKEKHAGMGELENMKNRPMILIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE61</accession>
    <name>A0A6A6PE61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE61"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21683" checksum="BAAED90D6358E0ED" modified="2020-06-17" version="1">MHAPTSNLATRSKVNKILFEGDPAMCVRVIDSTMSSGSSDDDAKTTVRASKLCFVPAYQNLGAWLGMLVETSKDYDAYSFRPASSGPLHHQPAYRDPEHRSSATEATRWSNPVVDHRRPDSPVDVDIMYQTIKSHAIGTRAKILRDMGGMVYEDLLVHGTNQLGIIDAGTTPTIVATMADQMVYTIVEKAGDVIKGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEE8</accession>
    <name>A0A6A6PEE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_368421</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEE8"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000085">
        <property type="entry name" value="Putative ras-related protein rab-11a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="216" mass="24158" checksum="7C01DD7F454F5A15" modified="2020-06-17" version="1">MANDEYDQRHPRDAYAVVLIGDSGVGKSNLLSRFTRNEFNLDSKSTIGVEFATRSIQVDNKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDISKHQTFENVTRWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTQDAKEFASENVLSFIETSALDATNVELAFQNILTDIYRIVSSKALDQGESSQNPIGERRTLEISKPADPENKGGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEK7</accession>
    <name>A0A6A6PEK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasma membrane iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_382984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEK7"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="346" mass="37578" checksum="3E631FF3B9B7E0FE" modified="2020-06-17" version="1">MPNVFAVPVFFICFRECLETSIIVSVLLAFLKQTLGLESDPQVYRRLVRQVWWGTGFGLLIVIIIGCGMIGAFYGVGRDTFAPTENIWEGVFGIIACLIISLIGAALLRVSKLQDKWRVKIAKALEARDTTKGVSGGRFKRWAEKYAMFLLPFVTVLREGLEAVIFIGGVGLGFPATAFPLAVICGLGAGALVGVLIYKGCSFAKLQIFLIISTCFLYLVAAGLLSRAVGAFEADKWNKEIGGDAAETGSGPGSYDIRQSVWHVNCCSPALNGGGGWGVFNSLFGWTNSATYGTVISYNLYWIVVIVSFVSMRYYEQTGHWPLMKGKANTVSVAKPTTTNVREVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKU5</accession>
    <name>A0A6A6NKU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxyphosphonoenolpyruvate phosphonomutase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_388663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKU5"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF16">
        <property type="entry name" value="CARBOXYPHOSPHONOENOLPYRUVATE PHOSPHONOMUTASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="27093" checksum="837A1C11C0934767" modified="2020-06-17" version="1">MERSAQDGLARKLRDLHVSGEPLVICNVYDAATASAVCSLPQVAAIGTASYAIAATQGIEDDDMTLEQNMVSIKNVAAAVAKTPLPLTADLQDGYRDVKETVRRAIELGAVGCNIEDVDNATHELRPLEDAVNRVKLAIEAAAEAGVPNFAVNARSDALPMGGTIEDTITRGRAYLDAGANTVFVWGGGGGRGVSRDEVTKLVQAFDGRLNVKLKMGPGSLTVNELKEMGVARISVGPELFQVAMTAFKEAAAGLLGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL22</accession>
    <name>A0A6A6NL22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_173738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL22"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="23874" checksum="5F099C6035D0FC42" modified="2020-06-17" version="1">MPHHLIIISAVQFSKVKMRAMWKLPALSFSGYFYSMPLLTHTSQRALETFTKSNIYSSSALRARSDIVSRTGAPCNVRRVRRLHRPKMPCTTRLAAFHLQLPAIPTYSVRADKELAASFGRTCTTYPAEPEPYVPYIRKVEPAACLPVSPDKFRLFAAIRPQMLQLPGETRRASGGRNVPSSLGAPKPYPACAARARGAMRDALRWRRVTGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLE7</accession>
    <name>A0A6A6NLE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative MFS myo-inositol transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_294548</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLE7"/>
    <dbReference type="OrthoDB" id="5290825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000100">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF26">
        <property type="entry name" value="MYO-INOSITOL TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="541"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="132"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="620" mass="70699" checksum="E445DDE3288AC73D" modified="2020-06-17" version="1">MAPRRDEEAVETDPPLNKEKSSPYNSDPEKESDIDDVHRRESEFLESVEKNANAALRNPLAGLSKKALFKDVETFAESKGLTEHIDILKKGALVAQNPSQFEMIEELSEEDKETLRMETTHRWKQPWMMYFMTVLCAGSAIVQGMDQTTVNGAQVFYTEEFGITDTWIRGLVNGAPYLCSVCIGCWTSAPTNHYLGRRGTIFVGCFASTASSFWQAVTDSWWHLFIARFFMGFAIGAKSSTTPVYGAECSPAIIRGALVMMWQMWTAFGIMCGFIASVVFFYIPAPEGWNIQYLNWRLMLGSAGIPPLFVGAQIFFAPESPRWYMTKNKYNKAFNSLCRFRNTKLQAARDVYYIHKLLQVENKLKEGKNLFKEFWLRPRNRRAAQSSFFVMFMQQFCGVNVIAYYSSDIFIQADFTQPQALLASMGTGIINWLFAIPAIYTIDTFGRRNLLVTTFPLMALFLFFTGFSFYIPNEQARLGCVATGIYLFMAVYSPGEGPVPFTYSAECFPLYIRDVGMSFATATTWGFNFILALTWPSLSDAFTPTGAFCWYAAWNCFATGFAYFALPETKALSLEELDQVFSVPTTTHAKYYLKMLPWYFKRYILRKDVPPRQPLYHLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLK5</accession>
    <name>A0A6A6NLK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Methionine aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_359529</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with zinc, cobalt, manganese or divalent iron ions. Has high activity with zinc; zinc cofactor is transferred into the active site region by the ZNG1 zinc chaperone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Associates with the 60S ribosomal subunit of the 80S translational complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="11"/>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLK5"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000010">
        <property type="entry name" value="Methionine aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031615">
        <property type="entry name" value="Zfn-C6H2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF15">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15801">
        <property type="entry name" value="zf-C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52013">
        <property type="entry name" value="ZF_C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C6H2-type" evidence="13">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2452367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="391" mass="43118" checksum="F305C52E80814105" modified="2020-06-17" version="1">MATEGSVTRKCLGVDCDNDAKDLQCPTCQKLGKESYFCSQDCFKRNWAEHKKVHKSASQRNTGHYNPFPSYSFTGPLRPVYPLSPRREVPASIKRPDYAADGIPRSEQGIINRSKITVLDKKGIEGMRKVCKLTREVLDVAARAMKPGVTTDYIDEVVHKACLERNSYPSPLNYYHFPKSVCTSLNEVICHGIPDQRVLQDGDILNIDVSLYHGGYHGDLNETYYVGDAAKNDPDSVRVVEAARGSLDEAIKIVKPGMAFREPGNVIEKYAKTKGCSVIKTYCGHGINTLFHPPPNVPHYAKNKAVGTAKPGMCFTIEPMVALGSYRDRTWPDDWTSTTIDGKRTAQFEHTLLVTEDGVEILTARFPDSPGGPVAMPAADAQPAANGTHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLL1</accession>
    <name>A0A6A6NLL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_358903</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLL1"/>
    <dbReference type="OrthoDB" id="5567124at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01168">
        <property type="entry name" value="RIBOSOMAL_S27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="15057" checksum="DCA1DDB440224DBA" modified="2020-06-17" version="1">MHQHFAPDEIEPSTAPAISTPRTANEPRCCHRESASTQAPSNQQQRPQIPASDSVKMVLAVDLLNPSPQAEARKHKLKTLVPAPRSFFMDVKCPGCFTITTVFSHAQTVVVCQGCSQVLCQPTGGKARLTEGCSFRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLT8</accession>
    <name>A0A6A6NLT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLT8"/>
    <dbReference type="OrthoDB" id="2958217at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="368"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="886" mass="99208" checksum="8DF7282377C457D6" modified="2020-06-17" version="1">MLSHPNFELFDSRRATFANDPTLADADVLAHAGFFVASDLSKATTCFCCGLQVASWFGRPDPIKHHIEQSPSCMWAKAQNECMSIIQNPSYGIFQEGARRVTPVKNTVALQTKQDSRLRKPLESGTISSGDEAIFGTREDFITGNMSMTLHGPHMAGELEAGGKLEARQLLVQPEMVLPDEESFKDIRLPSDKLCKICAGINFWKAFSSAAGDRPNIYWGYSATNCPVCRLVKQCFQSADVRTSGLKIAKGSLEPFATNHTTLAEIRRLSIELIFAGTEDADERSKLCIQATPLPTHASGRRNERSVLVGRSVNVDKVNFAAISRWISSCDQLHATCGAWPLSGMNFEFRVIDVLAGCVTRAPPKCRYLALSYVWGIGFDTAMLTRDNLQKLSQQGALFDTAISLPATIRDSMILCQKLGERYLWVDSLCILQDSAEDKHDQIVNMDTVYSHAELTIVAAAGVDCNAGLYGVHSQPRLRLSQSVALGEMRLITMQRSVIEQMAASKWNRRAWTLQELVLSNRMLVFTETQAFFYCAESLWTEDAALDDERERINLHEHETFSRQILHPSTLPTSSNVAFSEVYTDLVSSFVNRELSRESDVLDAFAGICRVLEPLLGEFHWGLPKRYFGLSLLWLPHGKATDGSDNTTVSEKGTSASVASAIPVGNKSTPLALDTAFKYTPSSFPAYAPRDAFPKWSWTGWKFEDTRVEFPSPAIYDLLLTLFVPDDPSSLQCIQRPTCDFDAIQSDVRMQLVPPSESDQGQIAPAVAEDLSRLIVFWSSSVEVELAKPWRWKETLYLVSKHSAQALPPWEFGKEWAEQLKLESSSQFRNILELIVVARMMNGDFVLILVKWEGYTATRVLLPWELRVPERWWASHRPTQRKIILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLX7</accession>
    <name>A0A6A6NLX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myoadenylate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_358400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLX7"/>
    <dbReference type="OrthoDB" id="1723809at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000214">
        <property type="entry name" value="AMP deaminase Amd1, putative (AFU_orthologue AFUA_8G02860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001251">
        <property type="entry name" value="AMP_deaminase_met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="63"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2452678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="680" mass="78001" checksum="ECFA3E3F82A2B6BA" modified="2020-06-17" version="1">MLAEEGLHGAGAGIGVGHGSGGFAASDASVEKELQTIYTNIQKVLDIRHKHIRLSLQGTFDNPKDDPGWRIYPPHPEPVWDPNKERAGAGASAGGGSLSNSTVLDSDMDLPQQPAARKQRKPGQDIGEDFVMDDVMPLPETSEMTYRLDENGVYQVYETTSSRGPSGEADAPPIVSIPTLREFYMDLDAILNVSSDGPSKSFAFRRLQYLEGKFNLYRLLNEYQEMADSKKVPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKMKKRPDEVVLFRDGKELTLREVFESINLTAYDLSIDTLDMHAHTDSFHRFDKFNLKYNPIGESRLREIFLKTDNYIKGRYLAEITKEVIEDLESSKYQMVEWRVSIYGRSVDEWDKLAAWVVDNKLFSPNVRWLVQIPRLFDVYKSTNLMDNFEQVVVNVFRPLFEVTKEPATHPKLHVFLQRVIGFDSVDDESKVERRLYKKFPPPRLWNTTQNPPYSYWIYFLFANMASLNVWRKQRGFNTFVLRPHCGEAGDTDHLAAAVLCCHSISHGLLLRKVPLLQYVFYLEQIGIAMSPLSNNALFLAYERNPFLQYFRRGLNVSLSTDDPLQFAFTKEPLIEEYSVAAQIYKLSAVDMCELAKHSVEQSGFEHAVKQRWLGENYWKAGVLGNEMAKVNVPDLRESYRHGTLAQELDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM07</accession>
    <name>A0A6A6NM07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_294283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM07"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="291"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="389" mass="42829" checksum="087B686187FDBB09" modified="2020-06-17" version="1" fragment="single">ANIPSIVFEKHRTLTSEHRRDWNMGLHWGAPLLRSLLPASSWSRIQTVQVDPHAPTPEHDHLNFLNAQTGEVMNALPVSFFYRLRRAKLRSLLAEGVDVRFGKRLHDASADAPGTSAPGTSTVTARFSDGTRATGAAVVGADGARSKVRSLLLGPSAGTLDTLPLAATFVQARYPRDRALFLRSFHPLYLGGIHPGGHFAFFGLHDAAAAAAPESWTFFFYISWRCGDDEDEGARLGWGDRERLAQAKRFAAGFAEPWRSAYDWLPDEHPVWYMRLTEWDPGAPGHGWDGRVGRVTLAGDAAHAMTYQRGQGLNHSVADADKLVGAVKAFVGGEVSRAQAMEAYEEEMKRRAGEEVRTSTLNSKMLHDWEKVLASPLFKSGMTKTEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMH2</accession>
    <name>A0A6A6NMH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_312083</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMH2"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="201"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2452443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="37801" checksum="6CB4EDFA8FFE4399" modified="2020-06-17" version="1" fragment="single">MGVGGGAERHREGHEKLESEASSPREEDEEGRRGAGGEGDATADRDEEDDLDRDVALKKVREREREKVKRQMQLGKNYEYFTGNTVFCWGGRLQNARDRPINIATGILVLAPAGLFFGFSAPWLWRNISPAIPIVFAYIFCVCMSSYFHASVTDPGILPRNLHPFPPPNPREDPLTPGPATTEWTMVISATSPSAAMEVPTKYCKSCNIWRPPRAHHCRVCDNCIETQDHHCVWLNNCVGRRNYRFFFAFVAAATILGLMLFGCSLAQLLVWQRQRRQPGGGGPGFGDALDANRVPFALMIFAVLGTPYPASLLAYHLFLLGRAETTREYLNSHKFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NML9</accession>
    <name>A0A6A6NML9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hexose carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_328902</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NML9"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF14">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="60"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="545" mass="59221" checksum="0480982539C0CC28" modified="2020-06-17" version="1">MATDIAKSAKATSSGDLESRHHEVVDPLSQSEPTAQFLEEIAYGPSGVRGVLSSPYVFGAAFLASLGGFSFGYDQGVISIINVMDQFHEAIPRTESAFGKGFMTGMLEFGAFLGCFFMPWLADAISRKWALTVVVVIFNIGGIIQTAAQNYGMLVAGRTIGGIGVGTLAMGAPLYISEISPPNLRGTLLVLESISIVSGVVISFWITYGTRDMTGEISFRLPLGLQLVCATILGVGIHFYPYSPRWLALVGRRDECLQTLTKLRRLPASDGRVQAEYEGIIAEVKFQEEMREKRHPGVSGFKLEIFSWLDLFRGKMWRRTAVGVGVAFFQQFSGINAFIYYAPTLFESLGQSTEMALIMSGVFNIIQLVAVAICFTIIDKVGRKPLAIFGGFGCAVPYMIIAVLSGLYSSDWASHSAEGWVSVAMAFTFILIFGVSYSPLGWALPPEVFPNASRSKGVALSTSTVWLSNFIVGVATPPMLDQIGYGTYIFFAAWCFLAGVWAWFLVPETKGKSLEQMDEAFGDTSGQEERAIMNAALTSARAKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN64</accession>
    <name>A0A6A6NN64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN64"/>
    <dbReference type="OrthoDB" id="4829316at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="75" mass="8406" checksum="952BF60D8594A134" modified="2020-06-17" version="1">MPSATPIRSFLASAKNFVKEPHPYSRFPATLQAHTHYAPFFTRQIARTASLYVPGAVFLLGWPFMVKAVLQRTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPB5</accession>
    <name>A0A6A6NPB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_356167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPB5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="53" mass="5935" checksum="19D7458378B8E7FC" modified="2020-06-17" version="1" fragment="single">MKGCLINKTLREELSTSRRACEEKVGDSRLGGCRHVNQLRTQQYGGCAVPLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPD3</accession>
    <name>A0A6A6NPD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial-processing peptidase subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alpha-MPP</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Inactive zinc metalloprotease alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Matrix processing peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_327284</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPD3"/>
    <dbReference type="OrthoDB" id="277191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000023">
        <property type="entry name" value="Mitochondrial processing peptidase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000032">
        <property type="entry name" value="Mitochondrial processing peptidase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="12">
        <location>
            <begin position="57"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="210"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="384"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="258"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="325"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="264"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00083075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2453549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="609" mass="65630" checksum="EB074FD516D3AE40" modified="2020-06-17" version="1">MIRSGLSRGLTRAVLRRAPVSLKARAATARRPFASVVAEEKDPVELDRVTTLPNGIRVATEALPGHFSGIGVYVDAGSRYENASLRGVSHIIDRLAFKSTSRRSADAVFEACESLGGNIQCASSREALMYQAATFNSAVPSAVGLLAETIREPRVTDEEVGMQLATAEYEIDEIWSKPELILPELVHMAAYKDNTLGNPLLCPRERLGEITRETVLAYRQSFYKPERIVVAFAGVNHEEAIRLTENYFGDMKGVEGPVLSGVGSETSISSPPSSSSSSTDSSESSFTSHQIQQQQPTYSSSTPPQEPSRLLSKIPFFKNISTSATSRASIDTTQPLPSSDTLPSSAPRSSLLATPDDLTRPSHYTGGFMSLPPQPPSPNPALPSFSHIHMAFEALPISSPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLFTNVLNHHAWVESCVAFNHSYTDSGLFGIAASCAPHMLPSMLDVMCRELAALTAPAGFGALQEQEVRRAKNQLMSSLLMNLESRMVELEDLGRQVQVHGRKVGVKEMCERIQKLTVEDLREVARKVVGGAVENKGAGTGAPTVVVQEADAGGVGGVRKREFGWADMQGLIRQWKLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPE2</accession>
    <name>A0A6A6NPE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_355660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPE2"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF76">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="220"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="566" mass="63365" checksum="34488B6A0C3001D3" modified="2020-06-17" version="1">MTQPLPKPQPETASGRDDDLGGWHSADEDDYDHRLSGEVAHHHRRCSESRMEEFDPDTGEPLDRKREQDHPPFRKGEMRHPFLQSTVDELAKDQHMGDYDRISSLTSGTTASPIMEEVRTPLEPTSEYMLSPVAATSPMDFPSQPTPWSERRTGSQRSRSYRSEKSGGGSMRRASRRSTRSGTNTSVSPASAFLSQWSKEEAAAPEPDDEGQEIGDHSEYIIGRQIGFGGFSVVKEVLTIEDNVKVQRAVKIVRKVVSGKTERENEKIQAEFEHEVSIWRFLKHRYILPLIAVYDSPFATFCITQLNVGGTLFDLVRKNRKESKRGLPAPLARRYTYQLASAIRYLHEDVRVVHRDIKLENCLLDMSGPSAATEGGNVLLCDFGMADFITNEHRQEESPEPYVQLAQEQVDLHSRPPLSTLHHQPASPELALHNANIGPSRTSTSVLPGGSLQYAAPELIDAPVALYSPAVDMWAYGVVCYALLAGELPFQHPFEPRLVMMILAGEWNEEALEKAPAVVGFSYDPIELVRGCLEMDPEKRLTVGGVLESKWLAGCKELYEPEEAWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ61</accession>
    <name>A0A6A6NQ61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_310079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ61"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="1">
        <location>
            <begin position="12"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="27733" checksum="77E83673283DCE76" modified="2020-06-17" version="1" fragment="single">MPPVPPRRAHDPLRLVLYAQTHHAPHTQTPVSLLPLLPTPLTHLIVGAFHLNATPGHITLNDDPPSHPKFDSLWADVRALQTHPNRPKKVLAMLGGAAPGTFTRLADPDPARFEAYYAPLRDCLRARAFDGVDLDVEERVPLACPLRLLTRLRADFGPAFVVTLAPCASALLHPRAPHLSGFSYFELAAEAARLVRPAPSSGAAAAAAPPLIAWFNVQLYNGWGDARQMGAYLGAVARAGWDPRRVVLGVLTAARNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ69</accession>
    <name>A0A6A6NQ69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SNARE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_114773</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ69"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF380">
        <property type="entry name" value="SYNTAXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="160"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="29619" checksum="B4CFDDDC8352F725" modified="2020-06-17" version="1">MRSQHNPNAILDECSSIDHALDTLESDLSALRDAHKMYANDDNVANTRRIESQGATLMNAYRALSARVKKVKSSPDSGSPRNAPQVGRVDRRLKKAINDYQRIDSDFRRLVQEMQARQYRIVRPEATDEEVRQACEDPSTQIFQQALLSSSRTQQAQSTLHNVRARHDAIQKIERDMIELAELFQDLDVLVQEQEPLVQNIVQKGEEVNENVTKANDEIGGAIVKARSRNRKKWWCLLICILIVIVIAVVVAVVVVINNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQM2</accession>
    <name>A0A6A6NQM2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_353827</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQM2"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="15"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="345" mass="37245" checksum="F12228464AB22BDC" modified="2020-06-17" version="1">MVPETMKAARFYGYGKPITIEDVPIPKPQKGDLLVKIRNAGLCHSDLMVIDNPESPYAIFLPLTPGHEATGTVQDVSEGVTDFKPGDDIGMNFQYYHPCGECKPCTRKIMARGCPTNRMHGFTRDGFFAEYVVVDSKSCIKLPEGMDVAKAAPFFCAGLTSFHAVDGCGLKPGDWIAIVGVGGLGHLGVQYAAKMGLKVAAVDVDESRLKVARDLGATLTWNGKDLADPADFKKETDGGVAAACVFTDSQLAYSTAVQILDLGGILMCAGLPDAPIPVVPLQLALRQVRVRGAWLGSPDEMDKAISFSHKHGVVPHTESFTLNQLPEMIEKMKKGQFEGRMVVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQM5</accession>
    <name>A0A6A6NQM5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_366508</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQM5"/>
    <dbReference type="OrthoDB" id="5329488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF10">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025453427" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="22"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="246" mass="26504" checksum="520923FA6C59CF4D" modified="2020-06-17" version="1">MFRRLDQSLIVLLGLVSSLATAHTVITYPGWRGDNLVNNGTLENGEIPTGALGINYENGSYTFPFGMQWMYPCGGMPTSTNRTRWPVRGGAVSVQPGWFAGHKNAFFYINLGLGTEPLNYSLPMLPVFQIIGPSNEMYAGEFCLPQVPLPENVEVNVGDNATIQIIETAQHGAALYNCVDITFAEPEDVAEVTEENCHNSTDAGKEIDFSLVFATTSLESAAPALSIGMSVAMLPVIAAVMFGFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR96</accession>
    <name>A0A6A6NR96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_326347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR96"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="105"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="420" mass="44496" checksum="5290140622049737" modified="2020-06-17" version="1">MAPLISSSSLRLPPQASAYVAAGAAASLSVLILRRAFAGSFQVPHPDDDAGITPSPLTTVLPHLTPAEIKALPYPPDALPGARDVPSPYGTFRVYEFGPNDGRKVLFVHGISTPSIGLAPIAQRLAERGCRVMLFDLFGRGFSSLPPSNIPHDTRLYTTQIHLALASSPVSWTSPSLDDITTDNPSETANRSPTYSMSSAHSSPSRTSPPPGFTLVGYSLGGGLAAAFTSHYPNLVHSLVLLAPGGILRPEHVTTTSRLLYYAPRALLPDWLAERLRPRPHSGSGRGPDPDAAPLLADRPASSVSGAVAWQLAHHAGFARAVLGCLREGPIHGQGRAWGRVGAGVAAARGRGREERRAVSKVLVVLGQRDGVVRADEVGRDAREALGEENVVVVVLDAGHGVPYECPEEVVGVMERNWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRC6</accession>
    <name>A0A6A6NRC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_292223</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRC6"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025402866" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="4">
        <location>
            <begin position="41"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="54879" checksum="D581129937FE7915" modified="2020-06-17" version="1">MKPNRALLPLPLSLLPSLSFAQSSSSPTDCSSSLTASYAAPSVASGFAARLVAQDLDRPRSIRFDSAGNLLVVEQGRGGVTGLRLRDSGEGAACVEVDERVDVTEDGDLNHGLELSPDGTTLYASSPSEVLSWPYDADSLSTTSDDPRTLVANMASGGHSTRTLLLSRQVPGLLLVSRGSDGNIDEDTRSISSGRSQIRVFDLNATAEADEPYDYTDGAVLGWGLRNSVGVGEYPGDQGGVWSVENSVDELERADEDIHQDNPGEELNFHGPLNASADAASDRFGANFGYPDCFAAWEVEDIPENGELRVGTQFAIGDLDEDDDDDDGVDDEVCAEDRTAPRLTFAAHTAPLDIVFDEAGETAWITFHGSWNRDDPDGYRLSAVRFSPDTAQPLADPTSTEAAIPIMSNPDLSACPDGCFRPVGLAFDARGRLFMSSDATGEIYVVVRTDEDEGSVEEGGVPTGLGPSETTGDAAAPSETGDEGDEEDEGAAAAVMVMGSGRSGVVWAVVGLGALVGGWLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRK6</accession>
    <name>A0A6A6NRK6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRK6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="143" mass="16074" checksum="A0A8BAC6A806B726" modified="2020-06-17" version="1">MRRPRLRPLRTSISMLRWACTGCPTTPFRLPSISPWTRAYSNIIIISSSSSIIPTGARRPCRACHPTEPVLLVPISTTGGRACQYGTRQRRRRCCSNKLNRFNNSSSSSSSNNISRNNRSSSSRSMPPVELRLHSHSNNIKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSF1</accession>
    <name>A0A6A6NSF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_266411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the stanniocalcin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSF1"/>
    <dbReference type="OrthoDB" id="2251794at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004978">
        <property type="entry name" value="Stanniocalcin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11245:SF6">
        <property type="entry name" value="DUF19 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11245">
        <property type="entry name" value="STANNIOCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03298">
        <property type="entry name" value="Stanniocalcin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16229" checksum="43EB29332415B6B3" modified="2020-06-17" version="1" fragment="single">TCSNPKPNSCAFYDDCLEDECQCGADGYPIGYGLHYCEEFTDAKSQMSDAGKDWVAETMLCLQNELVPWATGSRTGSCTQLKEYAFGTHPECYVNSGLCTLPPTDWIVVVQTVGLQELFGSWGALKASLQAAQGCGKFLAFLVERSIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSQ6</accession>
    <name>A0A6A6NSQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_381494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSQ6"/>
    <dbReference type="OrthoDB" id="3695313at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025654751" evidence="2">
        <location>
            <begin position="22"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="632" mass="67494" checksum="3EF9FDAB32311A37" modified="2020-06-17" version="1">MHSRYVPLSILFLAGAPGAWAQVSTTCLTEIRLATVTLTATPLPPAAILDVPGSGPTTLSSDGIPATIGTDTIGVDSAGSLVLNLNTYDFHNPIANCPAYLIPVVTPTGAASSTSSIVPPPVVTDDPPPPPPDEEDPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPPPDQENPPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPPPDEEDPPPPDEEDPPPPPPPPPPPPPPPPPPPPQTTPPTSDDDGECTTRTVDHCTQPCSFGTDSLGVTTTTSCRPEVCTETVGCTVVATTSTSTITPPSCPLSLGPRARYPFAVDGDGPVPTLLSSAEISIVDPGQSTDEPPAPTPTPGSTSTPEPEPTTSSPPPPPPPPPPPPAPSDRFVLKLHQQMDHEFSQLLWTLTLTNDEELASGQGDPVSADGLPHDVGITVHSPLNIEDTNIEFEYKGDGGDGCHPKWSTGQSTDNGSDPFKAPCRGPAREDYECDDVRNVEWVPWNGGFERKFECRFLGFDEPFDVIPRKTLESNTDVEILEEQTLEAREQEGRWKDPSYYWIDDLHGHYDTGEECEEHNRNDDLIKMIAGDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSR6</accession>
    <name>A0A6A6NSR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytidine deaminase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_106197</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSR6"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="198"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="438" mass="47264" checksum="170DD1216A7FBC8A" modified="2020-06-17" version="1">MGELVDCYAVEIPIKSSNVVLNLVKRSIRDFDSIPLLHLRRLAKPAYLPAHLRVQLPSSDNSPSPTDASTSTGSDTSPSISRSTSPASPTGSPPPTATPRPQTIVLLVCPIHLVSSERLTAILSTAAPFLPSPTLQVSPYPLKLLTLPAPLHPPTTGQAASSWTATHWPTVYKRNNPFGAHPAIVSRAESEIKDVAGKWLQLAQSVGQVCKEQGWGIGAGCVIVERSGGNNGKERSQTPTKKWERVVAVAGDARWYGRPDGTNTAATSQVESNPLAHAVMRAIAMVANKRLALGSDPSKKEQLLSSEPDYPFLSKPLTPLEARYASTTDNLSHNGYLCLDLELYVSHEPCVGCAMAALHSRFGRLVFGRRMQRTGALVAEVQAGKAFVDGGLGYGLFWRPELNWKGLVWQFQREVDTDGSEVCEENGADEPFSEETSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSX2</accession>
    <name>A0A6A6NSX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_95775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSX2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="278" mass="30644" checksum="A7BBF518155A3EB8" modified="2020-06-17" version="1">MTRKALASFKLKTKSFAYLPTPDPHPPRAHAHGRVHTTYFTFQQSPPNLSPSSHFPKIPPRPRPNPKLPPRPRGSAPRVPNQVTHHHKPTCQPPNSASIYPNRTRTIANGNPLLAGPPPFPLRPPGSLVARPSAHEYYALLRPTPPNAAVPSSIRSCPNPGDRSEISKQTPHHHSRRRRRRRRRRNPGRTEAGEDKGTASASTPDDVSALATCLARMQHAHAHCKATAQTERDKGSSAEREEVGSLLIYEESDGRRVLQSHGLAFIPRRLGGCGDRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT35</accession>
    <name>A0A6A6NT35_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_352398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT35"/>
    <dbReference type="OrthoDB" id="5401558at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="354" mass="38647" checksum="E033F0D719E20334" modified="2020-06-17" version="1">MYSQAHQVPAQTPSPWTSQPPQAPPPHQNGAYAPPQQNGIYPPPPPPPQLPQASTLVPPSPAEPRHDMNGVHAQPYRLPAPHEMYRGPPPAHDPYRPPHIYTAQHQPAPRQRTAIACRYCRRRKIRCSGFDSSEDGRCTNCNRFSQECVFTPVSSQAQAFVPAHAVWRGDGRPPPLYGAFGQPLRPSQQDAYRPPQQHQGQPPPPQQHPQQPPPPPGMPPQQQPQQPYTLQSPTASSAASYHTAQQQPGHQPPQPQPYYAAPPQRRSSPQSVYSYDPGRTSSSSPLAHGTPGTPNAPPYHYPADPQLRPGSQINPDGRTPPPATSVPGSGGRGGVAIRDLVDSDMVNQLDRRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT37</accession>
    <name>A0A6A6NT37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase B complex non catalytic subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_96478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT37"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="672"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="693"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="714" mass="81373" checksum="EE3714BCA95D5AA0" modified="2020-06-17" version="1">MSNRLTLAKVDELDKTYGRNHKQALKDCEKKLQKDPKNVVLQIWKANLLWKSPKQKDEAWDVCMGLCKREPPITDLEIVARIHEFAGLVLSRQNSSINSAGKEVQSMWQKAAKAAGKNQSNVFISMFQTSVKLDLWSDAQLAMLNLRNLNRDEPKYYFGYIAVSQLAADNVRDVDPKAAETDSKWAFAFLSKAVEQTLSNPSARNAVGSLNELRLVAQIYRKQGKRKELLSILDNKDIGITSKVGKNDPEFTKAKVELMEEEEMYADLYKFCYDILKAGLNAPDGSVETSDWSMWSHLMQSAAELPGKKDGKEVEELIQEYMAREPSQKERNIWMAYLSSSRIPKDAPRVDIERCKKYFDHFFELHCCFTDLRHLVISLELDERGSFVEYTISSTNAAPEPEDKADQLKWIMKKLNSLKFEYLLRAAKGDKQTLEAFVRKCLDLYKKRYELDVDASGPIAGDEAAVLAIMCLVKLHDLTTSKDVISAEKYYIQAAALCRPLIEKSPADRQVRLFAVKLYMLLGLGSMASEQYLFCRIKEIMQDTLSHTLFSRLSITHPFPSTTPASMRLEKPFRDSCTMLQQALTIYERSISKIRGFMGQALPTFQFDKALEFNDMIIRLSTSYTVRLLLVEFGRICRLRGQEQSALNYGSVDFDDWLSKLSDNRDDGITYDFEPPDLTPFASRIRNGPVPNPRSTSSAPRTPQTRPSRPSRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT68</accession>
    <name>A0A6A6NT68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">threonine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_352315</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT68"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000039">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF50">
        <property type="entry name" value="THREONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="83"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2454634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="59037" checksum="86C4E50C9B34BC59" modified="2020-06-17" version="1">MAALPWRVRSPRMLWISSRHAHWRMPAFASWMRACSTSRPPREPALDTTKAPPKPAADHRQLGTAQSLFTTSPYSPGSPLFLPNGASMFNKLVSFLRAQYPQFGFREVVTPTMYKKSLWQTSGHWDNYAEDMYEVRGRGATGRTAGGEIGEDDEFGLKPMNCPGHCLLFASEKRSYRDLPVRLADFSALHRNEVSGSLSGLTRVRRFHQDDGHIFCMPSQVQDEIRSTLEFVELTYNTLGLGPYRLVLSTRPEDHYIGTRAEWDTAEAQLKSALDASGLEWEVNEGDGAFYGPKIDIILKDSDGKEHQTATVQLDFQLPQRFGLEYVSATPEPGKGEEASIPEQNDPTVPVIIHRAIFGSLERFLALLIEHYNGTYPFWLSPRPAMIISVSQKLEELEYIRDVADIVRGTSNTFHQIEGSKRRRRAQPILRNPIHVDVDTSNRPLGRKIREAKLKGYNHIIIAGPKDVPQQSLDLEIHNQRNKVTVRDHLVQVLGNGTPESHVKITPAALRLYFEKLVDNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTF3</accession>
    <name>A0A6A6NTF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Invertebrate defensins family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_373527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTF3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025530269" description="Invertebrate defensins family profile domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11672" checksum="A8E38A5396E94077" modified="2020-06-17" version="1">MRTTFSVGLAALAFFLSSAGAAPPDRIAEDSPLHKRIPECAGNGGEGCPSGYFDENQCAASCYGRFPDTGDICQGYCAETPLWGGGTTPPQCYCSIYAKDLHKPFLVQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTR2</accession>
    <name>A0A6A6NTR2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTR2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="185" mass="20159" checksum="5160002814419E95" modified="2020-06-17" version="1">MLGNSLFHTSSGPVLPAAPSSCWTGLRGAKPGVRFGAPSWHLFSVENSSMRLPSRLAECELRDADVSMARAVGLKMERAPLQKGRNYNPRRSSRLYANGVDPISIGYSLPTSLRQTCLLGAPIIPPLFSLAPTETTHPNNHRSRPTPHPKIHTYKALKPHPPSAPTAPQTQPLLTQPLLIRPPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY6</accession>
    <name>A0A6A6NTY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative zinc finger in N-recognin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_387025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY6"/>
    <dbReference type="OrthoDB" id="10262564at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19677">
        <property type="entry name" value="UBR-box_UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040204">
        <property type="entry name" value="UBR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047506">
        <property type="entry name" value="UBR7-like_UBR-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="4">
        <location>
            <begin position="37"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="450"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="498" mass="51067" checksum="5AD95B305F319F55" modified="2020-06-17" version="1">MATAAPDPEAPQTAQDFIDSQLRLEADAREALPYRFDACTRPLGALRQSLFSCLTCNPPPRDPAGVCYACSIACHGEHALVELFSKRDFVCDCGTARLPPSAPCALRGGARSETPAPANRYNHNFANRFCGCGGDYDAHAETGTMFQCVGLGSADDGGCGEDWWHPECVLGLPRDGRRPRRAGGGDGDGDGDGDDEPPLPPGFPAEDDFDAFVCYRCVAAFPWIRRYAGSDGFLPPVYRAGPGDGDGAPAAAAAAAAAAPAARDAPLKRGPDRGSPDPRGRPGDGGSDGDGGAKRRRTGGPSPACRAPAGSADPSRPLSLFCKDGFRASFCRCADCFPPLARHPCLLEEEETYEPPMSDDGGGGGGSGADGASAGTGSLLDRGEAALSNVDRVRAIEGVMAYNHLKEKVKSFLAPFAESGRPVGAEDIKAYFEKLRGDADGVGAAAAAAGGAGSSGGGDGGGGGDDGAGRREQSGEFTSRPNRGRRSSAADGVPSSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUD2</accession>
    <name>A0A6A6NUD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUD2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17090" checksum="2474D7E56836BEF2" modified="2020-06-17" version="1">MDDGGRDARPGHPSPRRGAARSLPSPGRRGVEVGRLPPALLLLLLALLLFRLLAAAQHTHGSGEASRSRAGAHALGREGSEEWERQLYGAGRQWEHPGSRTAGQGTAQAVEQQELAFRDSWGVIVETRRTRSDWRIEVDLLQMMLETTCRYCDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUY1</accession>
    <name>A0A6A6NUY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_67194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5330058at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1310"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="838"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="976"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1373"/>
            <end position="1390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1396" mass="155658" checksum="FACCF6F447392500" modified="2020-06-17" version="1">MEAYPQQTYTLPSQPHSPFPKQCADNVWDSRHHLRTWSRVNLELSGVPLPRRLSAIEVFCPTHHKYDLAEQPICRAAPNNPVKKKEKIQYIDVVSTWKGLTTSRAYEVNFWETAFQRALEKVTKEHILEQWFVDGRNLFGGSQSAEMMRHLDEFITRARCFRVPINVNNLFTIMLTLYQEDGKHHVWLAQSPNPSASLVEFIRTRECFDFDDSDGKPFIRVCCSTRFTFPNNLLIIGDLAWFPPRLEFLSLPTVVREGADMYFVPSYKEKGLNECFEEPATPTEYVLASDHIPLKWVADIKGFHGVAPPGMARRLRAAPSNGLGSDGRCALVIEFQLTTSITKPFPKDVRFERIVRLKLGVEISEPETQQTWPARTRFAAEDAAPWKTTALHDAKKNPFLNSQTLGHNFGVSRPFARPEIPDFSLSARPPKASTPRNVLQTGNHQDLGDEPKQDVLTIPGWDIKVRSADDVSFLRGWLQSQLVPVQGVLKESLEECIREACQVVGIDACEVFCETHVPRGVPLRPTKDLDIQSDRPWLLPVPSEPAQPQTAQPGNGSRDSSGRSNNSAANKSVSPPHDPLPVRHVRQRGSTVGREREPTYNREDVPSEIWNAAVVETTKDMWPGTVEPSMPPPSSIDHIDWAIRRWCDITAADKKSEGESTISPLDLGEAEENTQQLRQLYEPQSVDGAIKADDSGPFDHVAPKHHPHYHVPSFLSNANLESHEAKLGHLDVALPPPSSASSIKANPDEDQENAGQVTPRECQRKKGKGRAQDGEAQQWRLLPLSSVQANGGALIRSAVPQKRQTRASLRDEFHKQGDPGDAWSRPLLHGEKDHPATDEGESRDEIDMDEAYKEEPDWLSEDEGGFLDMEPWEPKAFEEWQERQMKLEREQQGDLKSLVLAALKERRTLLEKTSKVKKAAKTEDAPTQDPSAMEGVSLIRFHEAMRKLSESSKDDGSKSGSRKGKEPLKDSLAPVSTSSKEVSPSSSSSYREFADYHQMWPVDALRPLPSSASRKSNSSNESQAGSSSLGLSEKLSHTYDFLGDFLSLERTFPLLSKNGKATPEMSTGEGPSDQSKAKGSSKPSEKDEPMWTQEREYLGSPVSLHDAMMASHHFHDTMTAHRVSFKGPSHNPHDPLFVEAWGAYLHDFEQKLPAPALPTWVSDYADDPAANPERASTATAVQAHWKVLNRELGRARQRHDGVAAFVAEEGAWNALESERKREVRTYAEDSVNYLAPRVERLAQVLAQLRGSWNKAKGAGAGPSTPEEKRPHGRPLTPVPDSVMRPAERGVTGVDPDLVQALYVRNFREDLERAESRRSKSARGSSPEKEHDDDDGDDDDSEEESEIGSDDDSSERRAFEEAFLESGTASVAADSEDNGDSEEVDKDDGDGDSGSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVA1</accession>
    <name>A0A6A6NVA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="6">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_69366</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="6"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVA1"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="123"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="556" mass="61033" checksum="BFCE470C7F4DBBCF" modified="2020-06-17" version="1">MGSATRLTGLLQKRCLGTAFPRSSTLAVPSRAPWKGTTCTIWRPHLIYRNRIVREASSSSKSVAYTSDFYPGIKRNPNFARLTPEHVSFFKSLLGSASGLVDGVSTDATEDIEPYNVDWMRKYRGRATLVLKPESTEQVSRILTYCNNNMLAVVPQGGNTGLVGGSVPVFDEIVINLQRMNKIRSFDDVSGILVADAGVVLEVADNYLAERNHMFPLDLGAKGSCQIGGNVATNAGGLRLIRYGSLHGNVLGVEAVLPDGTILDDLSKLRKNNTGYDIKQLFIGGEGTIGIITGISVFCPQRSTAVNVAYFALDSYKKVQEAFKEAKTQLSEILSAFELMDGNSQKIVSQVRGRKLPLESEAPFYCLIETSGSNTDHDSQKLENFLENVMSSEIVSDGVLAQDQTQIGDLWSCREGIPECLGHWGGVYKYDLSIPITELYDLVTATRGRLDAAGLMSASDKSLPVVDAVGYGHMGDSNLHLNVATRRYDKKVEEALEPFVYEWVAERDGSVSAEHGLGIAKKDYIGYSRNETMVKLMKQIKDLYDPKGIMNPYKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVG2</accession>
    <name>A0A6A6NVG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_264498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVG2"/>
    <dbReference type="OrthoDB" id="4388755at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF4">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="30"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="287" mass="32209" checksum="0712C31292C2D66B" modified="2020-06-17" version="1" fragment="single">TNDCTLFSINGSTIGNFTHYRFYDFRDVYADDAAADSSSDDAIPQSRTIRDNTWMDQWSRRDQLKEAWNDNIIDMEYNARNIYIENSTEDSGDYSTFLTLYTTRLADGSQQAGEFDYVEANVTYLSLRLLARVSGSSGAVAGFFTYHNDTSETDIEVLTRDPTSAVHYSNQPTADDEDNIIAGATFNNSMPPGQPWDDWQVHRLDWLPGQSVWYVNGVQTGATRINVPDVAQMVILNMWSNGGSFAGRMEVGGEAYLNVQWLEMVYNTTDVETPGSDGDPTVCFIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW31</accession>
    <name>A0A6A6NW31_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW31"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="104" mass="10406" checksum="6C265F331A557DD0" modified="2020-06-17" version="1">MADVREALGPVASSSTGGGGGGGDAKKLARWDWIYVDGDDVQAFRNALFGSAAGAGARKKAGGGTATGGDGAQLLAGGDRTVPKIVGREYIVQSLILGALVDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW46</accession>
    <name>A0A6A6NW46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW46"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18320" checksum="AD1B344723EEBDBA" modified="2020-06-17" version="1">MIWSQSVFRASNEPTNQSPEYGWLLAFSEGKKRACKLATSILSNALFYLSSSVSRNLNNQYFLFFCFVLFAEKGKEKSSKTRASCCAQVMSTCLENLRSKEPLKIHVPLANVVLHAMAHPFQSDFALKNAANSKKLSLSIPRGQVTRTRVAPVTQHHSKPVIAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW69</accession>
    <name>A0A6A6NW69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_288913</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW69"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046557">
        <property type="term" value="F:glucan endo-1,6-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF43">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="74"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="511" mass="56940" checksum="ECEC2B6DEE32EDF5" modified="2020-06-17" version="1">MAPPDGVDATAPVSAEDFHRYRWGQGGNFGAVFVLEKWMAGSMFPDAGDGQTSELEAARIWTDREGLEGARVRFERHWRDMVKDERIEYLVNTARCTLVRLPVGFWTCGPQFCQGTPFEPYGMVWVNAWATVKSLVARLADNGISTLVDLHGLPGGANDGEHSGTNIKQALLWQDRRHWHHSVAALEFMAHDLRGVPGVAGLQVCNETCYDARGMYDFYDEAIAAISRADSGLPIVISDGWDLPRAADYAMHKNSLFSGVPNPTIIDTHYYWCFAPKDTSKSPQEVIDDVGNKLSELDGREGDVTTRGAVQVFVGEYSVVMAESTWQKVDGSERDEYTKRFGQAQQARWQSRAAGSTFWSFTVEWYPGGGWGYAAQINSGALPVPPHLTLPADEVRARLARADAERQPRLDKAYADHVGWWGRDGFEHWRFQRGWDVGFADARAFFGWRSAGGFAQAAAGGASEGADTIGAREVWVRKRLLDSGSRKEKFVWEYEHGLRKGMSDFYELVGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW89</accession>
    <name>A0A6A6NW89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Guanine nucleotide binding protein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_288534</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW89"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010255">
        <property type="term" value="P:glucose mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000181">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF369">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="149"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="174"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="268"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="351" mass="40425" checksum="4A3BEA0AF7D1E5ED" modified="2020-06-17" version="1">MSTASEDSEQKKRSQAIDRKLEEDSRRLRRECKILLLGSGESGKSTIVKQMKIIHQNGYTQEELAMYRLTIYKNVIDCAKSLIGAMRQFDIEPENEGNAGFCDYLMDYTVDPDPEKPLEFEVGRAVSSIWRDPCIARVMEHQSEFYLMDSAPYFFDEVSRIASPEYTPIEADVLRARTKTTGIYETRFSMGQLSIHMFDVGGQRSERKKWIHCFENVTSIIFCVALSEYDQVLLEESSQNRMMESLVLFDSVVNSRWFMRTSIILFLNKVDLFKAKLSRSPLGNYFPDYSGGNDVNRAAKYLLWRFNQVNRAHLNLYPHLTQATDTSNIRLVFAAVKETILQNALKDSGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWJ7</accession>
    <name>A0A6A6NWJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenosine deaminase/editase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_61854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWJ7"/>
    <dbReference type="OrthoDB" id="10268011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043829">
        <property type="term" value="F:tRNA-specific adenosine-37 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042935">
        <property type="entry name" value="Tad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47803">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47803:SF1">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="410" mass="45482" checksum="714EA00A8F44D7F3" modified="2020-06-17" version="1">MPVNGDNIANCVLAAFDGLPSKSKPRRRTDEKREWVPLSGIVLEKAGGPLECVALATGMKCLPTSRLPQASGNILHDSHAEILAIRAFNRFLLDECAALKADSNRFVRRREWIELSDEEPQPFALVQDVKIHMYCSEAPCGDASMELTMAAQKDVTPWEVPPAAEDGAQEKLRGRGYFSELGIVRRKPSRPDAPPTLSKSCSDKLALKQFTSLLSTLASFILSPRSAYLSTLTLPRSQYIADAISRTFSPIGRLAPLTLHSSPTTYASWQEAGYSFTPFETLTTEREFVYSRRSVSYGLEKESQPVASNISALWTPRVHETLVNGARQGRKAGDLRGASAVSRRRLWEAVVAIVDAEGKQRLNVRTYRELKEVNGDIMLAKRQAVKKASKKLLLGWKQNVGDDYWEMNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWP7</accession>
    <name>A0A6A6NWP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_57598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWP7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21469" checksum="255EF4EA8BBA0A8D" modified="2020-06-17" version="1">MQSETKEGLNPVMHQIAEATNNTKRKAVAVRPTLGPWWLVDQYIEPSNSPEAHQQEKSSGILLGHIDARVTYGVRLCVETGDWRENKDWNVPKRPQSRPSVSPTSYQRGQALCLLRCATHDRPHGAGQAMTSSGSSQSAARRWGSARAMPRSGRQMGPLAQPGCGTPVLKRRTCLMVQHLNFHERRRGRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX19</accession>
    <name>A0A6A6NX19_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_348463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX19"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="11157" checksum="98EE119F99EDE7B3" modified="2020-06-17" version="1">MLRFSAALYSTMWYSLPGVPALLPNQPTGIRNARWPRTSRHSGPLSTTTLQLMPRRPRLVTASQRRGQRTPRSHWPVPQNSSAVSRPASRATFSATSTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYD3</accession>
    <name>A0A6A6NYD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_364725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYD3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="495" mass="56717" checksum="65877E4957B626B5" modified="2020-06-17" version="1">MATNVSPVPPDHGNDPYGVYHFVENTVFRGNMPDDDDGPGVERGVSFRTDHAYNEPFALHTIGDDFKHNLFSETSPLCSLMRPQRFRNGTDTPRLFGTQLNARWKGDGIIIQHFCMPTVSVAPDRVQTICQVPLAHNFIFHEWMLLDSELKTLMDGLNLKSDPSPSSNQRDTFNFMKWLVLTCNVVVVAEGFFRNAEDLVLFVQGRSIMWTRSTPLNPRRKCYWFRSTPRHFRGFLRSHMPSEGDIKTKAMVLELSSTADDANTWAETHMRREFETMFRNLWYAHIADSEDDCDIIPIPIDPDVGTVPTNPLQTVSYIIAMRVALAAHDLGNHEFFSRCRHLWRNMAAWPLPERPTPTGDLFEHDLPALDPLELTSNSSCYILAGPAFSWEGSGPSWDHRPYQPHMDCYRSCRPNRCSNHVQSAIYAWPTGSLWLKKVEYYRQLLECGLRLHEGLRRPFIDLLSSAACFGEVAELNSAYRKVLLAHRCQAYFARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYT5</accession>
    <name>A0A6A6NYT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_392992</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYT5"/>
    <dbReference type="OrthoDB" id="2574at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13592">
        <property type="entry name" value="PBP2_HisGL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.120:FF:000003">
        <property type="entry name" value="ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000123">
        <property type="entry name" value="HIS1p ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="59"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="15">
        <location>
            <begin position="231"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="32935" checksum="EDE7CF38751F3222" modified="2020-06-17" version="1">MELAESLDGRLLFAVPKKGRLHQACLDLLSGSDIQYHRHTRADIALVKNLPMGLVFLPAADIPTFVGEGRVDLGITGRDQVAEHEAGTPPTPTTGVEEVLDLGFGGCKLQVQVPAKGSIHRPEELVGRTIVTSFTNLTEAYFRDLEGAAEEKPRLRTTVKYVGGSVEAACALGVANGIVDLVESGATMQAAGLKAIATVLDSTAVLVKSKRPSDPKLVDKIASRIRGVITAQKYVLCVYNVERSKLDQACKITPGKRAPTINPLEESGWVAVNVMVTRKDIAVVMDELDALGACDILVTKIDNSRTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ46</accession>
    <name>A0A6A6NZ46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ46"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17699" checksum="77E9093FF197BFB2" modified="2020-06-17" version="1">MRTEIRSARTSAAAFACFPKSWKNLKGSPSPAYLTSTPSPSATAPDKSLSSRQAKAFIGAFQTLPKHKLYRFYFFFLVFIFLFHLTRQGVSPRVFESPHELLHRHLSQGRHVIMNRTPSPVHNQPLRSAGIYLWPSTGPAPQRPSSNLHPPPSPLDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ50</accession>
    <name>A0A6A6NZ50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">VLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_347478</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ50"/>
    <dbReference type="OrthoDB" id="429841at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VLRF1" evidence="13">
        <location>
            <begin position="244"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="491"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="553"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="568"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="622"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="661" mass="72697" checksum="A85D702C51BB2FAB" modified="2020-06-17" version="1">MPPKPEEELLQRPLYVFDLPEELLLTLNLKEQTSQSPETDKNEERKKSPSPSPERTSTPEGGPAIATSCALCGLSFPNLEEQRGHVRSDLHGYNLKQKIKGLKPVSEADFERLVGELDESLSGSDSSETDSEEEVEEGSNKAKDTTLTALLKRQAKIVAPEDDDFVPKKRRRGPGKPPLLWFASSLLPKNVSLGIYRAIFSDAEQETEGKIVETIRNKQLPPMPPPGKPVQDGSGGVKLPDAKQSPHYLLCMIGGGHFAGMVVSLAPKIGKRHTGPTEERSASVLAHKTFHRYTTRRKQGGSQATNDAKGAAHSAGASLRRYNEAALTADVRQLLAEWRDLIDMAEMLFIRASGSQNRRTLFGPYDGQVLRSNDPRIRGFPFSTRRATQLELMRAFVELTRVKINRVDETSNAVAAAAAAAGPSTPPKAATPSKPVKSTLSREDEAAALHTTQLTALIRRSKAPALLSYLSSNALSPDFRFFPPDAPAHHHAPTPLHLAAASNAPAVVLALLTKARADPMVRNGKDQTPFEVAGDRATRDAFRVARGELGEEAADWETAGVPAALSKAEAERRDEAEKRDAGEKEKERKKAEVERLRKEEQEREASRREARVGKGKLLGKAATERSAQERREEETRGMSEEARRRLEREQRARAVERRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZR8</accession>
    <name>A0A6A6NZR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_392093</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZR8"/>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000111">
        <property type="entry name" value="Transcriptional repressor rco-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="9">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="372"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="407"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="455"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="493"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="544"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="586"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="14"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="626" mass="65971" checksum="4D8C6A7834F7F99E" modified="2020-06-17" version="1">MYGAHRGMVPAAPNNRLNELLDHVRAEFDQENARATDFERSLTLQIQEMEQVRQKVYQLEQQQIAIKNKYEEEITRLQRELEARGGPSGSHAMAHGPPAQPPPPSIGHGPSNLFGGIMSGNAAGGAGGAGGQAGQHPSLAPPPPEPQPASGLPTHLSAAQHGAAMGPAGAAPGPGPAGPAPAQAGPGGPPQHPFGGYGQGPANGFGPQGPQPTASPGPKRGARGPPGPATPQQHPAVPLPGSPQVPRPTPPPNAQQALMGPGARPPPPPTAGGPNVGNCLAELEPDQVSDAFKTDGSDWYVVYNPQIRRSLDVKLLHTLPHASVVCCVRFSHDGRFIATGCNRAAQIFDVESGAPVAHLQDPSLPEDGDLYIRSVCFSPDGRYLATGAEDKIIRVWDISMGSIKTSFTGHEQDIYSLDFARNGRLIASGSGDRTVRLWDVDTSQQIMQLSIEDGVTTVAISPDNRLVAAGSLDKSVRVWDTASGFLAERLEGEQGHRDSVYSVAFAPNGRDLVSGSLDKTIKMWEMGGATRVGAPKGGKCVRTFEGHKDFVLSVALTPDGEWVLSGSKDRGVQFWDPRTGIAQLMLQGHKNSVISVAPSPSGKLFATGSGDMRARIWRYVDHPKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P054</accession>
    <name>A0A6A6P054_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="7">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_286383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="7"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P054"/>
    <dbReference type="OrthoDB" id="3781271at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025568341" description="(4-O-methyl)-D-glucuronate--lignin esterase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="4-O-methyl-glucuronoyl methylesterase-like" evidence="9">
        <location>
            <begin position="102"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="392" mass="41924" checksum="BCDCDEAB2AEAE420" modified="2020-06-17" version="1">MRSQPFAAALLSFLARAIAQDSSSCPSTPSPWPEAGSFPVTPTLPDPFLYLDGTSRVQTQEEWYSCRKPEILDMMQHYQYGYYPDHALETVTATRSGDTVSIAVEADGKTAQFSASINLPSGASADAPAPVVIAIGGMDNNAYLSEGIAVVTYDYLSVAADSNSKTGAFWDLYNGRDIGTLVAWAWGFHRVLDALEQTAGEIDATKVGVTGCSRLGKAALAGGLFDERVTVTMAMSSGVQGLGPYRYHALSGQDETLENSKQGAPWWSDSTLADFIGQSERTPFDAHTIAAALAPRALVIDQGTGDPFTNSEGTAVVVYPAAKIVYEWLGVGEQIGMAVRSGGHCDFSGYTNVLPFVKQIFFGEASTRDYDDLSPWSPMPEAYPWASDVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0D0</accession>
    <name>A0A6A6P0D0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0D0"/>
    <dbReference type="OrthoDB" id="3692311at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="30031" checksum="30D35EAD72A74F83" modified="2020-06-17" version="1">MHFNTVTAFATLASFAAISIRMKLCRTRLFLSQSRRAPTLPRLTYYVCHNGFKGCSTNPSVCDLPGETTETAETPEAPNAAPEMPPSADPPAPYRMCPEDWTYVVEGACPSGFKGCVPDANSLCGPQQSFHGTCPESLGQYYVCSNGFKGCSTNPDVCSYTTTVEGPVETTDAAQPPVVVDTPADNNQCGGYPSTPSQPSNNTENATISNTEEGRPYSMCPEGHAYVVEGACPSGFLGCTADATTVCPPPRRFWGTCPTGHGNYYVCSNGFKGCSTNANVCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0X7</accession>
    <name>A0A6A6P0X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_371671</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0X7"/>
    <dbReference type="OrthoDB" id="19014at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000135">
        <property type="entry name" value="Arginine N-methyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="10">
        <location>
            <begin position="235"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="465" mass="50365" checksum="F66EC7C0528A4A01" modified="2020-06-17" version="1">MDPAADMDMTLDTDIETQSILLAAANHDVRALRALLSNRAGSANVQDPETGATPLHAAIAACEPDAEGDDTATAGAASANGAAANGVTHVNGAGGDAATVTAEEAGKESEREKLMEEAGKTVKLLLQHGAIWNDLDANGETPGCIARRLGLKELYDLMVDAGVRAELLLGRLDEYQPLGDGDGEGDEDDAGEDENEGRVAEGGDAEQAQGTVESGNATVASAQEPSQDQSQQNLTNSDVNNAKYLASNLTFTADRLLDADANGVMMSWETNLMSRSAELLTPTEGLRILNVGHGMSIIDTEFQKRKPSMHHIVEAHPAVLERMKRDGWYEKPGIVVHEGRWQDVVPQLVEENVMFDAIYFDTFAEDYRELREFFSEYVIGLLDPVGGKDGEGGKFGFFNGLGADRQICYDIYSKIVELDIYEAGLDIEWEDVKIGDLDASGEWSGVRRRYWIPDKYRLPTCTFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P180</accession>
    <name>A0A6A6P180_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_385473</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P180"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="9">
        <location>
            <begin position="51"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="370" mass="39717" checksum="6120DEC0E00759B8" modified="2020-06-17" version="1">MPSSDVVENPADDVRVIGYDPLIPPALLSSELPVPPTAAQTVLRGRRDAIRIITGEDDRLLVMVGPCSIHDPATALEYCGRLRDLAERLAPDVCVIMRAYLEKPRTTVGWKGLINDPDIDESFQINKGLRVSRKLFCDLTATGMPIASEMLDTISPQFLADLISLGAIGARTTESQLHRELASGLSFPIGFKNGTDGAIGVAVDAIGAAAARHHFMGVTKQGLAAITRTSGNEHCFVILRGGSKGTNYDAESVAKVKEELRKKGQKEAIMIDCSHGNSNKNHRNQPKVADTIASQLRAGESAIVGVMIESNINEGNQKVPPEGSAGLKKGVSITDACIDWDTTVGVLENLAEAVRERRKSRPEKESNGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1C6</accession>
    <name>A0A6A6P1C6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_385515</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GDT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1C6"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025520701" evidence="8">
        <location>
            <begin position="22"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="57436" checksum="8F4A315B3024D26B" modified="2020-06-17" version="1">MRMRRRASPFLLLLLPTLAAALSTDNAAAPAAAAAADADVQRTVRDAAAAVEPDPIAPASSLPTNKLDLGTKDAPVDGLDGKPHKGPWVESAETRAKKKPAAAVEDILAAPAPSSSPLGGGPQADASSDGGWQLMEPDGVMDDLSHPAPKEGTTGTEGGISEKDRARKAHEEQTGSKLETAPDPPKEAPPLPHVDQEQAVDDADRPKGAPGLETPEDLPDKPHDIPHPYPASSEYDPLAKEPPADIQPGVTTGDGTPLEDEDPSGVIQPFHSFILSLAMIIFSEIGDKTFLVAALMAMRHPRLLVFSAAFAALITMTVLSAVLGHAVPTLLPKRFTSFMAAILFLIFGAKMLREGLAMSPDEGVGEEMKEVEMELEEKEHTMARRNSRRRSSISPYVLEAGRAPHARRSRSNTRLPAPPRSPSSSPSRSPSPRRNRLAGLLTGLNNLFSLLLSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDYWWVTSGAIVGHAMCTGGAVIGGRAIAGRVSMRVVTLGGAVAFIIFGLIYLVEGSYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Y3</accession>
    <name>A0A6A6P1Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clock-controlled protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Y3"/>
    <dbReference type="OrthoDB" id="4094614at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038843">
        <property type="entry name" value="Sed1/Spi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523:SF1">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025568712" description="Clock-controlled protein 6" evidence="1">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="17653" checksum="B2C1924AC8164FA9" modified="2020-06-17" version="1">MRFATVATVAAGLISGAAASWGPMYNHTGMPEYVTEVVTAYTTFCPGPTEITHGGATYTVTEATTLTITDCPCTVTKPVMTSTYEVCETCTPVYTPPVESTPLPSYTPPVYTNGTTICTTSTPAAPETPETSVYPTGTGAYTTPSSPEFTGAANKAAAAGGAGLAAVMGLAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Z0</accession>
    <name>A0A6A6P1Z0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_343492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Z0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="53" mass="5927" checksum="0EDC2833E50E2F0C" modified="2020-06-17" version="1" fragment="single">MRGCSINKTLREELSTSRRACEEKVGDSRLGGCRHVNQLRTQQYGGCAVSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2B4</accession>
    <name>A0A6A6P2B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal RNA-processing protein 7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_385308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2B4"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12950">
        <property type="entry name" value="RRP7_Rrp7p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="4">
        <location>
            <begin position="11"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="3">
        <location>
            <begin position="198"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="319" mass="36415" checksum="884AAFA803DBA26D" modified="2020-06-17" version="1">MSLPSITLGDFVVLPLTFPPLPSFPRAVKHNLYLRPYVPHTEDPNSSEQKTLFVTNLPIDATEVSLRKLFKDQLGGYLLNSVRFDDDIRSGNSIADTNSSTARAQATKGKKRKHPGMVDAASVERAEIMTLPRTWDTIPLKSGSSAVLVFVDIASAEGALRAAKKAAKSQTEIMWSQAMDPDESSTGELRYRRHQLASFPPAHVLQRSVNAFLTHFNSLEALRERLRTQQRNVPDEEGFVTVTRGGRMGPARQEEAEQALQKVREKEEARRKEMGDFYRFQWREKRKEKELNLRKKFQEDVRKVEGMRKRKRAIKPERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2F8</accession>
    <name>A0A6A6P2F8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_343242</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2F8"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="31084" checksum="B6C2031F171FF626" modified="2020-06-17" version="1">MSSFRASARVRSQFVPSTLPRLVRNYSAPSTSYEYILVSTPRPGVGLVTLNRPKALNALCTPLIVELNDALRKFDADLSVGAMVITGSEKAFAAGADIKEMKDKTFASAYGTDFIENWSDLAAQIKKPVLAAVNGYALGGGCELAMMADIMYCSAGAAFGQPEIKLGVVPGAGGSQRLTRAIGKSRAMELVLSGDNFDGKKAGEWGLAAKVFESPQECVDGALGLAQKIARHSRIAVKAAKEVVNKSQDLGIREGVEYERRVFHSLFGSRDQKIGMAAFAEKKKPEWENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2H6</accession>
    <name>A0A6A6P2H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HSF-type DNA-binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_285122</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2H6"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000229">
        <property type="entry name" value="HSF-type DNA-binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF396">
        <property type="entry name" value="FLOCCULATION SUPPRESSION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="343"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="638" mass="68079" checksum="53FAE3AA4AC99A45" modified="2020-06-17" version="1">MASTAESMRRSPFAADHHATSMHHKSIPILPSSNGPANSPGHTPSDPMDVTPTNPTGPMGPPAGTNQSNASGEQQAGNGQHVQQQNGKSESEQHQHQHPTTNGNSGPAIGAAAAAQQPKVVQTAFIHKLYNMLEDQSIQHLISWSSTNESFVMSPSTEFSKVLSSYFKHTNISSFVRQLNMYGFHKVSDVFHTGSPDSPLWEFKHGNGNFKRGDLVGLREIKRRASRHVLTHRDSFSTGPKASGGQPGTPVEPMPDPVESRFSALEHNLYEVYSRLARAEDSYAYLNSKCQYLTDGITRAHQWNVEMAKIITAMVPDADNPIARDIAAMQRDMARHIEAMRSYDDPQEPLPSARQPYFANLHNDTTPLSPRQMAQDTDSRRPSLGSNSLRGTAAAAAAAAAAGSSSLRPPQAPASLAISPRRYGSIGAGSSYSPSSARNPVPPPPPPPPVMPHPLSTASSPPTNLPRRHTSADIRLHGWQGAPPPPPPPPPPPHPAAAAAAAAAGHSPYASGQNSTQWPSSPHRAPVDPADLQIRNALAQYELPRGPSSSRSRQATPPAPDAPAGAPDSGGGGPGGRGAPGWSLPAPRFPQFKTSFSMPPTRRSSMASNVHSLLNPAETAEREDEDGPPDERKRKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K1</accession>
    <name>A0A6A6P2K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Signal recognition particle receptor subunit alpha homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Docking protein alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_385275</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2K1"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005785">
        <property type="term" value="C:signal recognition particle receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14826">
        <property type="entry name" value="SR_alpha_SRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17876">
        <property type="entry name" value="SRalpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000566">
        <property type="entry name" value="Signal recognition particle receptor subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.140:FF:000009">
        <property type="entry name" value="Signal sequence receptor alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000023">
        <property type="entry name" value="Signal sequence receptor alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007222">
        <property type="entry name" value="Sig_recog_particle_rcpt_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04086">
        <property type="entry name" value="SRP-alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="12">
        <location>
            <begin position="639"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="145"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="666" mass="72089" checksum="6C10047A072BD804" modified="2020-06-17" version="1">MLDSFEIVSTSGIVLWSKKYAIVPSNVVNSLIANVFIEERSNAPATADRDDASAARNPTYKTDGYTLKWTTAKDLGLIFVAVYQSLLHLSWIDKLLDNVRALFTELYRSQLKRPNTTVVDCGGFDGYFDRQVQELELRASAIATDSGASAAEFTPPSSSGTDRSAEERQEEQPPPMPSLKPPPAKAIYDDTSNDATPVPTPETSRPNSPAVNSHLLAAKGTGPRGKLSRRQRQRQNMAGSAPASSGDENPRRQQKARSSKKSRKWEADGTAVSDDEGDANLDYSSAPRDGPTSAPAPPIENVAQESWGKRTGKGEFVLKDLDEEMDEIIAAANAKKEGRKDANAGIVGSGLGAIGGLFRNVVGGKTLTKEDLEKPLKGMEDHLMRKNVAREAAVRLCESVERDLVGLKTGSFTSVETTIRQAMESALQKILTPTTSLDLLRAIQSTNAGTPQRPSRPYVLSIVGVNGVGKSTNLSKLAFFLLQNKLRVLIVAADTFRSGAVEQLRVHVRNLQELSQREGGEVGIYERGYGKDAANIARDAVSWAAENAWDVVLIDTAGRRHNDQRLMSSLEKFAQLARPDKIFMVGEALVGTDSVQQARNFNAAFGAGRGLDGFIISKCDTVGDMMGTLVSMVHATGIPVVFVGTGQHYTDLRTLNVAWATRLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K3</accession>
    <name>A0A6A6P2K3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">H+/nucleoside cotransporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_284359</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2K3"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="620"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="241"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="322"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="426"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="654" mass="72123" checksum="AB8BE57077E83C60" modified="2020-06-17" version="1">MALPNHNSSPEIGTVPNPDPALDRSHEHTHAHLHHSDRAERGREEEVVYSQGTTAEKSTIPDQGLMDHDLHRRHHPERMAHSEDVEKGGDIEKNAVLDVDDPEKGSVSPARSPEKDPQSHKFANFYRKYKIVFHAVIWMLFTGWWIAGLIEHRHDKNWIIPFLLWLAITLRIIFLYVPITIVSKPMHFVWNNTGVRIAALIPDKFKIPAGAALVVAVILVGTFASPENQDNSRENRAVSLFGLLVFIFVLWITSRNRKAVRWHTVIVGMLVQFIIALFVLRTKAGYDIFTFISTLARELLHMANEGVAFLTDEDVPNLPWFFVSVIPAIIFFVAFVQLLYYWGLLQWFIGKFAVFFFWAMRVSGAEAVVAAASPFIGQGESAMLIKPFVPHLTMAEVHQVMCSGFATIAGSVLVAYIGLGVNPQALISSCVMSIPASLAISKLRYPEEEETLTAGRVVIPDDDEHRSANSLHAFANGAWLGLKIAGMIVATLLCIIALLGLVNGLLTWWGRYINLDGEYDLTIELIVGYICYPIAFLLGVPREGGDLLKVGRLIGVKLIANEFVAYDMLQNDEAYADLASRSRLIATYALCGFANIGSLGTQIGVLSQIAPSRSGDVSRVAVSALITGAISTLTSASIAGLLVTDEQAYFAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Q0</accession>
    <name>A0A6A6P2Q0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_285050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Q0"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13993">
        <property type="entry name" value="STKc_Pat1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000549">
        <property type="entry name" value="Protein serine/threonine kinase (Ran1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="29"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="314"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="47785" checksum="84C5462A14E5125D" modified="2020-06-17" version="1">MYPTPPPSPTLNGTCAPEARLGHVLAGRLQLETILGVGAYGVVYTAIDLQDGTRYAVKALNKVGLELRQRKFQEREIQLHYQASQHPNVVSLAKIMDSPDCTYVVLEYCPDGDLFANITERSRYVGDDLMAKSAFLQILSAVEHCHNLGIYHRDLKPENILVTDDGMTLKLADFGLATSDAASSDFGCGSTFYMSPECQQPSPKAFSCYASAPNDVWSLGVILVNLTCGRNPWKRASLDDSTFRAFLRDPNFLKSILPLSPELNAILRRIFELNPAKRISLQELREAVIRCESLTAKPSAPTVMPQEYPAKYRRPCPVETRAPDYTPGVPSPLSPPGNMPAELHPAPTHVSDDSDVDSDDESVFSSGSSASSNSSTSSFCSPSSYANVANFQPYVIHQQQPAYVSTPPGPWAPLHAATSYFKNRPFYPRMGVRVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Q4</accession>
    <name>A0A6A6P2Q4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_421083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Q4"/>
    <dbReference type="OrthoDB" id="62012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="272" mass="30519" checksum="44BE4B43A5DA5550" modified="2020-06-17" version="1">MAPFQMCLGIPETVLAQTSPTSFLPPTLFARDISPASKTCDSCTDLLDGDNPPLYLYCGHGFHNTCAVKFLNPLRNEQLTATCPACKDETTTLWESVPLWALFGSGRDTWRFKPYFVGIVIKNCTINDFNWAVDFKKIHCKEMIIMVGKTNMAKAVSAGDPLHEFYPKQILKSPEPGFWVVKGISCFSYTWARLFYDDASLWWAGGSLEPAVPRLVYQFIAMKDPDEPDWDPAWEDEDEDEDEDEDDDDESDAKATNAAAFEHNGRLSVTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2U2</accession>
    <name>A0A6A6P2U2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_371173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2U2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="69" mass="7454" checksum="0E6FCF268CE1EB68" modified="2020-06-17" version="1">MSGAMGMYQMGTPSTGIYGQRQPMNQFAECASVELIWTTSSDEPIHGRGRHLKTFSEPLSISDTANSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P365</accession>
    <name>A0A6A6P365_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P365"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="181" mass="19755" checksum="7FD4A993A46B1F78" modified="2020-06-17" version="1">MTCRTEPRPCPPFLLWRAGKQYIAHASLPHAAGLAQPFGVRRLNNVCVLITALLDLPEPPSNPVLADPARPLERELRPLAPFSQKLPDLNSFISNSLGERVVTRAAPLLRTFPSRAANKLGRPGLLRRASSRERRHPASHVRSRRTTVRISRAPIAPPSTGPPISQPCAGVAAGLHLELFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3H3</accession>
    <name>A0A6A6P3H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Distal membrane-arm assembly complex protein 1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_205753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3H3"/>
    <dbReference type="OrthoDB" id="6604875at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028036">
        <property type="entry name" value="DMAC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053092">
        <property type="entry name" value="Mitochondrial_unc_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28048">
        <property type="entry name" value="ACR195WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28048:SF1">
        <property type="entry name" value="ACR195WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15055">
        <property type="entry name" value="DMAC1_Dmo2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Distal membrane-arm assembly complex protein 1-like" evidence="1">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="101" mass="10801" checksum="BD5F51D2097DC256" modified="2020-06-17" version="1">MSKDIQSLQKPPKLEDALAAQRAEFDDCLPCRLMGSAAFVGLGAYSWISGHSQLNSEEMRARAAATAARKGGRSINLATRKLGVKGISLALVGMGLWRLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4H4</accession>
    <name>A0A6A6P4H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_283180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4H4"/>
    <dbReference type="OrthoDB" id="338650at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000824">
        <property type="term" value="F:inositol-1,4,5,6-tetrakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF103">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="343" mass="36100" checksum="C04CA84D852C51AC" modified="2020-06-17" version="1" fragment="single">SDGVLADPSGEMIIKPCTADEIAFYESANSSHPAFAAYMPTYMGTLSLDKPEAAESAAATAEPTASGTAATLGLDDVGPMHGKALETSRSIVLQNVAAGFSKPNILDIKLGAVLYDAASTRPEKRARLDKVAAETTSAPLGFRVAGMRVWQGAAAAAADAAAGSTSGVAGTDDTVSLDRAANYKEFNKIYGRVFSADNVLAAFREYAVVPAAGVTPQMALDVIRGFRAELQNVQRVLEQEESRMFSASLLFVYEGDPSRYKAAKEAERTTPAKAKAVEDDDAESEDEPPKVSALKMIDFAHASWTPGLGPDENALKGVRNVGKILEDLYSELEVAQDQAAGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5R3</accession>
    <name>A0A6A6P5R3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Norsolorinic acid reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_362632</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5R3"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="392" mass="44245" checksum="9336B5FFFA79D0F2" modified="2020-06-17" version="1">MAFSMPPPPKSVLGVHRVLAPKAAVRVSPLCIGGMNFGENWKSFMGEIDKKTVFDMLDFFVDQGGNFIDTAIDTLGFKSRANNYQGGESEMWIGEWMKERKNRDQMVVATKYSTYYPFGEPEPKIRSNFVGNSAKSMHVSLHDSLRKLQTDYLDILYVHWWDYTTSIPELMENLHKFVQQGKVLYLGVSDAPAWVVSKANEYARQQGLTPFAVYQGKWSCADRDFERDIIPMCRDEGMALAPWGALGAGMFKTEEQRAQAGGRNLGPVQEKHIKMSEVLERVAKRKGTIITSVALRYVMSKTPNVFPIVGGRKVEHLRGNIESLKLELTKEDIEEIDSAIPFDIGFPHNFLFETGGGKYSLDSQADSIFIHKLGAYTQHVEHQKPLPPPKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5S7</accession>
    <name>A0A6A6P5S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ESCO1/2 acetyl-transferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_377767</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. ECO subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5S7"/>
    <dbReference type="OrthoDB" id="428854at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028005">
        <property type="entry name" value="AcTrfase_ESCO_Znf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028009">
        <property type="entry name" value="ESCO_Acetyltransf_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45884">
        <property type="entry name" value="N-ACETYLTRANSFERASE ECO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45884:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE ECO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13880">
        <property type="entry name" value="Acetyltransf_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13878">
        <property type="entry name" value="zf-C2H2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="N-acetyltransferase ESCO zinc-finger" evidence="11">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase ESCO acetyl-transferase" evidence="12">
        <location>
            <begin position="455"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="530" mass="55068" checksum="E50D80F0574DB028" modified="2020-06-17" version="1">MKTYSRRSLLSTGASFAPDEKRRRRDRLADDSSALGSVFPSATCAPSSSTTRTSSSSPTQLASSDPAALCEGASTPPSSPPPPAPEPTEMERAAPAWGPGRGLKRKREKAASWPGEEGERTVEKQDDEKDENGDGDEHGNGRIHGKIPGDRSASRRRRRAPLTETPDDNARRAPCSSRRHAAPSAPHPSRKPDPPTCPAHLPPRQLNLDPARAPAPKPKPKPKPAPKRLTQLRLSLHPLDAPPPSRKTCPLCGMSYTATSAEDAALHQRFHAQHERGVDMTRGFVEWAAGGGAGGGAGGGGRIVWRAAGGGAVVVRVRARDRGVARKGVARVLEVVERELGAVALGEAELWGGAGAGGEEDAGKSETAAAAGGAAAREERFVAYVYLRGGRCVGFCLAERIRRAWPVVAKAAAAAAASGATTDADSTTAAASDPTKTAATAALPPALALGPAPRAATLGIARIWTARAHRGAGVARALLDAAAGSFVYGVRVPRERVAFSQPTEAGARLAARWFGGEGVGSAFGECELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P619</accession>
    <name>A0A6A6P619_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING zinc finger-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_282195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P619"/>
    <dbReference type="OrthoDB" id="5405791at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056929">
        <property type="entry name" value="Znf_RING-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25080">
        <property type="entry name" value="zf_RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RING zinc finger-like" evidence="2">
        <location>
            <begin position="428"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="491" mass="52995" checksum="15668E5343F8D78D" modified="2020-06-17" version="1">MPPRASLTSSFSVSDANNEVVCPLRNHDGSACRKRCLGEKRYRSMQEHIRRAHPEHYISKLPATEESFLLMVNTPPSERPQPPPPSQQQQQQQQQQQQQQQHPAAASSAVTTSHSTGTPRTSDEYRRGSLLPAASAAAALAQLHNHRPESDWESEQDVHSEAELNSKPRAHFALEPLRYHASEEPQYTSQGFQRRELLPSSIARSPPGRSSTLPPAGAPPATSGGGGGGGLSRGSGSFKSSSGAGSRPRKSSVGQNARRPKHERTKSREQKRMSHERKAYSAEPQSAAALFGKRWEDLLDAATSATEEDSRDLTPVPSSPHLHPINPHQQQQQQANRASLPPFAASFPHQQQAYTASPLQRALTPPPPSDPMSSDLAPFPSVESSAGADSSLNSAQSTQSGSLFHMRGLLSSDSDTAPAPVAPPPVEIYCAGCHRVSALHDGYACTECICGLCQPCVDVLVAEQGRRGRVAKCPRCGTVGGKFKPFQLDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6D6</accession>
    <name>A0A6A6P6D6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gaa1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_384579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6D6"/>
    <dbReference type="OrthoDB" id="445301at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304:SF0">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036762">
        <property type="entry name" value="GAA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="692"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="715" mass="77262" checksum="579061C4C9070B49" modified="2020-06-17" version="1">MVSFKSADRLGGLGEKPHAAPRTIRGSETGTFRDLETAPELLLTTSSLRLLRLPPFLSLLCLLVGVAWLLLLPLDAHSRSTYVSENALLPGQVHTYFGGSEHNVFRAYRHEVAALAELPDDHAGDAERIARLRGIFKSAGLKVATQEYGYETAVGREVKGENVYAVLQGPRADATEAIVLMAAWRNMAGELNHSGVALVLTLARYFKRWSLWSKDIIFLITPDSIAGPQAWADAYHSPSLSSSTVSFPNTNANHNAANRCRIEPLPLKAGALQGALAVDYPAGPWGHRFDKLHLVYEGANGALPNLDLVNTAVNIARGQLGIGVALQRVWNARKGGPAEVYEDRLAALLRGVVAQGVGVPAGPHAAFIPYRVDAVTLQAVGDGWHDEMGLGRTVEGLCRSLNNLLEHLHQSFFFYFLVSTERFVSIGTYLPAAMVVAAGYTIMAIALWVGSGRLEVRKEGAETEVEQTTEKTSKASGSRLEKKQPDSQIDLNSTTPSTDDRPIALPLAFVVAVHATGLIPLYLFNHLPASLLLPLYVLATVNALVLPALTAAALRRLVLPAAEVAARQFLMLVHAFSLLLAGLFLSALATINFSQSLMLGLVGWPAVWVPTAKSRVVSAALYTFLQLLSPPAVLAIWAAWWTYSSASTMAAPKVWNSGVDRRDVPDGIVQAVQMVLVRAAEAWHVSGVWTPVVVWLVWWPCWVVAAVGAGVGWVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6H4</accession>
    <name>A0A6A6P6H4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vesicle coat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_420108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6H4"/>
    <dbReference type="OrthoDB" id="5599713at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="2">
        <location>
            <begin position="423"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="806" mass="80526" checksum="46D629C11CC86BE2" modified="2020-06-17" version="1">MDFIISLAHFCEKHGPTSILCTQIVPVACPTCHPCAGGTPSTDDLPRSSAGTGSSGFPFAYEPPPPPSDTPKPSTTTTPTAANAQHGDRDAEKHKGSHNLHQHHQTRFATGGGPTSLTASPAALETPPTSPRTPSTSSHNPYFPSVSLGTAASPPPLPPPLPRQHAATISTTAGMMGPGGAPQYQAAIGPGAGGGTRFSDAFFGAGAGAADEACENCAFVVPRDVSARLPDGAPGSPTKDGRGRNGCPVLRTTQNVLVVGGGGDGDGGRAARREKVAGREGRRSRGHVGVRGGGGGGRGGDGCTSQGPVAVSDSEGDSCGSVNGGVPVDAAKVVAAAGGNASSGAATTVPHLSSSSSPPSVRSPSPSTSPSPSSSPHSPSSSSPCSASPSSPSSDGGTFSHAHAHAHTQRSHHSPHQRHHHHSHHADQDPQPHSHRLTYLTTRQPSSPTAYSLLRRSCIRTLSCESLPRGSSSGPLYFGDPVAGYTIAYIFRLPDPMARGARRTYALLALGGRESCRVSAAMVMVTEVFERMAADVVARAERVLERREREGWAAGGLGGLGLSSSFGGYGGGGLPLRTGSVSGAVGAGGGPASSPGSPLAPRPGAAASPVRERAREQQAKEKKDKEKEKQQADGAATPGPGPGPAPAQASPKHAPAAPAQAAPTSPTSPTSPTKTSSSATTTISAPTAAPPAASAASRPPPPGRLQSHSHPPSPMARTHAGGGPAGAGPGAGAGAGPGPHSAAGITPVSSFLSAKKVDPDGYPRGPEAAGRPRGKGLAEIVGQEGFFVEVHARFCVLLGRLVGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6L1</accession>
    <name>A0A6A6P6L1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sensitive to high expression protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_259290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SHE9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6L1"/>
    <dbReference type="OrthoDB" id="5595506at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008839">
        <property type="entry name" value="MDM33_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961:SF3">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05546">
        <property type="entry name" value="She9_MDM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="22774" checksum="63F5847BB3C4B011" modified="2020-06-17" version="1" fragment="single">RISELMDKLQEHFAMAGQKVNRYTGTDYSGIEALRREIKEQERLVKARRSAVNEAKDALDAAHSQQGASQKEVVGLLERKHSWSAQDLERYMALVRSEHINDQAVQAAKDRLHAAERALEEARSQLERRERAQYHEEQIWSDTIRRNSTWVTFGLMGVNIFLLLVNLAVIEPWRRRRLVKEVRRALDEKTPMVAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6W7</accession>
    <name>A0A6A6P6W7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_336334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6W7"/>
    <dbReference type="OrthoDB" id="7344096at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="103" mass="11771" checksum="EA266395631BCE78" modified="2020-06-17" version="1">MPLEVPSRDEMRRIAAEQDAREAKLKAVRKRRASAARWGGAGTPPTEEEAAAQVIQRNYRGYRERRQMQGLGLDASTRWLEVCLRTRSFLPAKRPKSIFECAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Y3</accession>
    <name>A0A6A6P6Y3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_281691</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Y3"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="580"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="756"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="845"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="622"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="849"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="876" mass="94930" checksum="B8CEACA1DBE88ACB" modified="2020-06-17" version="1">MSRVGHGLARVLGIQLPDRALPRPATEGLSRGESIFSIESAESYVEEEPTAREWLAGMAPSRRDLLRYLAGLFPFAQWLPRYNTRWLAGDLVAGITVGAVVVPQSMAYAKLAELPVEFGLYSSFMGVAIYWFFATSKDITIGPVAVMSLVVGNVVADAATRIPDVPGHVVASALSVIAGAIVLALGLVRLGWLVDFISLTAICAFMTGSALNIAVGQVPTLLGLEGVATRQAMYRVAIDTLKNLGTARLDAAVGLTALVLLYAIRILASKAAASRPNHRQLFFFISTLRTAFVILLYTFIGWLVNRNRRGDSAFILLGTVPRGFQHAAVPTLTSSIVSTFAGRLPATVIVLLIEHISISKSFGRINNYTINPSQELVAIGVTNILGPFLGAYPATGSFSRTAIKSKAGVRTPFAGVVTAVLVVLALYALPAVFFYIPNASLAAVIIHAVGDLITPPNTIYQFWRISPLEVPIFFAGVLVTVFSSIENGVYTTICVSVALLLYRIFKARGRFLGRVKVHSVVGDHLLDGSEERKDYGAVNIPRKNSRRLTDGDHEAAREIFLPMDHQDGSNPQIEVEAPYPGVFIYRFSEGYNYPNANHYLDYMVDVILKETRRTNPASYAKPGDRPWNDPGPRRGESAEQAAAADPRPTLKAVILDFSSVNNVDVTSVQHLIDVRNQLDRYAAPDSVEWHFACVNNRWTKRALVAAGFGFPTPGANEPGQWHRWKPIFSVAELGGQDSAAAAAEYSLNERTRRRAAARRRDLEEGGGGGRALTQSKAYGLHQQRDYADAAAAVTANATGRHGGDGAQARAYRPPQQSLLQTRVAVVHGLNRPLFHMDLTSALQSAVASAERREAHEKEKGKAIEKGGVEEGEGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P792</accession>
    <name>A0A6A6P792_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidoligase enzyme-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_420167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P792"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23659" checksum="1D59B7964AAF33EB" modified="2020-06-17" version="1" fragment="single">MARAGESIRAIARPSEESHGTWTFTTDHTIEISPAMMDSYNPEQHFRAVGIELRSPVMDLARDEWTTRIRTIVNKLKEAIDGDCSPNQPTRLVLSQKCAMHVHLSDGPEVRASFEACKKVLMLQLGFERQLDEALTVSRMWGNKWCRPLSNCWYDYEIVAGFPPEFQALSLTAEDKMPDWDPLDAVRFLWGFGPDEIDNLWISQSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Q0</accession>
    <name>A0A6A6P7Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Endosomal/vacuolar adapter protein YPT35</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PX domain-containing protein YPT35</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_281594</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YPT35 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Q0"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07280">
        <property type="entry name" value="PX_YPT35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037917">
        <property type="entry name" value="Ypt35_PX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="152"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="262" mass="28598" checksum="FB7A31857F82C410" modified="2020-06-17" version="1">MEEPQSQAHKKTEQQPPPRCCPPPRRTASSDPSSARTSPTASPAPSPAAAAADDDNHDGHDDDDGGGGSGGSSARAGASPSDLVPPYWEHWTHPADRRRRHHWQQDQLRHAGCAGGNGGSTVSVDSFRPAPIRLEDHTVDGSEQGKALWARCVTVEDYVIVSGNAPGVGAYVVWNCTVETLDGGPMMIRKRYSEFDELRHNLIKTFPHCTAALPQLPPKSVISRFRPRFLERRREGLAYFLNCVLLNPEFAGSPVLKDFLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8A9</accession>
    <name>A0A6A6P8A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_276631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8A9"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF50">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="62"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="384" mass="42397" checksum="23D801276D3ECEC0" modified="2020-06-17" version="1" fragment="single">PYVLRYGRRYLREMPLYPLPTDLPELQRQNMQTLLATSVFGRPLCGPAFSAAADGGARPKRVLELACGSAYWTSLCAEYLARGRGERDVTFVGVDVVQLAPDLSRQGIRWRFVRHDLRKVPLPFDDGDFDLVMMKDLSWVMPIGLPSQRLLDECIRVLRPGGTLEVWETDHVVRSLAPHPPPTPSGQAGRRAEDDRCAAQTATFPISPATPFTTAHNGFLQDANAWIQDALDRRKLPPTPCTRVSQMLLQEPESLTDIDCRRVAVPLGEPRWEQAEGVATGTRSRKNSEAGAGAGAGAVGGGGVGAGTRAAKSLLTEEQQALRHLALLNVVQKIESLEPLLKEVSGKNQEEWQRWWSWMMADLLENKGASSGECLELGAWWARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8C5</accession>
    <name>A0A6A6P8C5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c oxidase subunit 12, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome c oxidase polypeptide VIb</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_334772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase subunit 6B family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8C5"/>
    <dbReference type="OrthoDB" id="1107506at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00926">
        <property type="entry name" value="Cyt_c_Oxidase_VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.140:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 6B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003213">
        <property type="entry name" value="Cyt_c_oxidase_su6B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281:SF8">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 12, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00074891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00082359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="101" mass="11741" checksum="D365FEC5A254BEF9" modified="2020-06-17" version="1">MSDDEERVTKPFKFVTAGFDARFPNQNQTKHCWQNYVDYQKCIIAKGEDFAPCHQFKLAYRSLCPSGWTERWDEQRGECFFLPSSSPLLFPHHPCISSTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9D3</accession>
    <name>A0A6A6P9D3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_276607</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9D3"/>
    <dbReference type="OrthoDB" id="2355at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="19148" checksum="47B7DE50F268D237" modified="2020-06-17" version="1" fragment="single">AALPKPPATIDPTAVVAAHAVLVGTHPIRIGRGAVVHPYARLVSTHGPVDVGDGCIVGERAAIGLGEPGAAASAGAADARVALGRNTVVETGAVVEARETGEGAVVEAGARAGPGSVMEAHSKLAPTVRLPAGVRLPAYTVVYGPAPDQRRVDTTLRGSNTVQALRDQAHARQLELLRKLIPSNIAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9J5</accession>
    <name>A0A6A6P9J5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_280552</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9J5"/>
    <dbReference type="OrthoDB" id="412536at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000152">
        <property type="entry name" value="Extracellular endoglucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005102">
        <property type="entry name" value="Carbo-bd_X2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016282">
        <property type="entry name" value="Glyco_hydro_5_endoGlcnase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF41">
        <property type="entry name" value="ENDOGLUCANASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03442">
        <property type="entry name" value="CBM_X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001043">
        <property type="entry name" value="Endoglucanase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="41"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding X2" evidence="11">
        <location>
            <begin position="354"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="555" mass="62084" checksum="7332F3C00D8458AC" modified="2020-06-17" version="1">MRARSAPACTGTFEPISAQDFVDAMNPAWNLGNTLDAVEDEGDWNNPPVQDYTFDDVIAAGFKGVRIPITWAYHFVSESPDWTVDPEWLQRVEDVVDMAVSRGLPTIVNVHHDSWIWADVSLDDAHIDMIEERFYQLWYQIGQKLGCKSQLLAFEPLNEPAGSTQEHAQEYNKMNEIFLKALKDAGGLNSQRVVTLVGLNMDAGKTSQWFEPPTINFTNPWALQYHYYSPYDFIFSAWGKTIWGSDNDKTALDTDLSIMRNNFTNIPLIIGEYAASPVATETAARWKWLDYFVRAAVKYNTPTVLWDNGNDFLDRSTHTWHDRSAIDIITNATAGIANSLADSTVDPNADTQWTSAYVFHEVGDGVGEQSLPFIFNGNSVVSIFTIEGDELLEDDYSISDDSITLSAEFLSQYFSTDGAPGVKGEVLVSFSAGADLGIQIVQWDTPILGTTSASLFSVQGSDLYIPIEWAGLSKPATVKIMRRDGTIVFDDWTQWLGPLQQGRATYSNQWNWDDSNLIVALSAISTIASTNQTTWFEWEFYPRVPGNTVNYTLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA07</accession>
    <name>A0A6A6PA07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDCD5-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_335986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA07"/>
    <dbReference type="OrthoDB" id="10252486at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="135" mass="14901" checksum="F736CBE2A1B5609D" modified="2020-06-17" version="1">MSDADLEEIRKARLQQLRAQQGSPGAGGGGEGSGQDEQKRREAEARSAILNQILLPEAADRLGRIRLVKESRATDVENRLIMLARSGQLRAKVTEGQLKDLLNAVAEKEREEGADRIVISRRKGGWDDDDDLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAJ6</accession>
    <name>A0A6A6PAJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_333788</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAJ6"/>
    <dbReference type="OrthoDB" id="9987011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Luciferase" evidence="3">
        <location>
            <begin position="168"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="294" mass="31680" checksum="E55E4998E9A6CD71" modified="2020-06-17" version="1">MATQGASPILLTEMSTVTSFAITTILLIPALSYLYVLLRRDYDDFLSLGPGGTPSTPLGYLRIKILSFFALRDPCRAAPVPPNLRPQRGYLSMSTLPVRAGPRPRVRGIAPHRQMTQRGPPNIFNALAMRLQALAAYERNGLALGTSCFEKHSTGLFCVSPVLRTCAGEVCHAHGSDGSLHLTLHPADAAAVLASGWGERHPLAKGGWLSRFVPAGFIMVYAPRDEVELEVVMQIILASAWWVGGRIPRPAGEGAVESRKPFTAVGLVPDSEGDNSADWAARPCQTTSSMVHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAV7</accession>
    <name>A0A6A6PAV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAV7"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="2">
        <location>
            <begin position="153"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="2">
        <location>
            <begin position="269"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="344" mass="38449" checksum="295878928218B4E3" modified="2020-06-17" version="1">MLGRGLLGRLQADVAKRSAPFELALGKARIRATGSACSYRSYVRASAGVARASRATALYRRQLLDDSRSYATATKSAGRPARKKSTTGKKAAIKKKSPVKAKTKAKAKGKAKVKRATKPKRQMTPERIEAKQKKLERQKLQERKKEALLKEEPPRGRNTAYTIFVAEKLPRGKTQGQSGLASISQVSSEYKNLSASEKEHYNHLANEKNTAADAAYKEWVASHPAEKIRTANLARRYLRNMKRAKPEKEGDSAKKRRSRTPADIPDERSVKQMRNAMIFFVQDRFASGDFKGIAPHEAMNVIHKEYAALPTNEKSTYLDKAAEDKKRYVIEYTRTYGHAPATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAV9</accession>
    <name>A0A6A6PAV9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_167593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAV9"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="216"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="696" mass="78759" checksum="AF8BDCA6203FE3ED" modified="2020-06-17" version="1">MALCSLCRSIPLTNLPTLPTSFYSYHAPGHNLVPMIRDRKKIVPGEEIGFSHQPGLDSLRRSALNCELCELLEEAAKGLIANLQEAEKVDSSKYIAKEGFPPTFQLWLTQRLDRAKGFLIWTDTQNSSAYLIGGVTLSVNDDSHLSHSILGRPMTEPMGSLLTLNRARKWVETCNDCHKGCRPRHNLLPRRVIDVGENGSTEPIKLYEPTKTTGDYTILSHHGNSDHDLATISEAIRRDGLAISELPKSFQDAVTVTRHLGIRHIWIDVLCMGQSEDGGYGDEDERMDTVISNAYLSIAALGAADDSDGCFLPRPPRKYVELEYVEKSENGDPIEQGTVLASLLGLRHASYWSNYTSLDGEPLSRWAWALQDRLLAKRTLFYGSNQLFYECQSEFKSEDGFVVPCDPEYFDIPSVTARFKFADDQDKRWPTHPWSKTDESHEDRVYNAWADILWFYGDMKLPRSSDKLPALSSIAHRFQDLLQDTYVAGLWRKRLVSQLWWQKVGFRKNDPKPAIEYRGPSWSWAGLAYEAKIGRLRSEDWVEVASIVGCHVEPKGLDSCGEISGGWITLKAPVERLELSDEPERDADKISDQVKEIRAPRLRTKTGSTYGDYALLDERQGRSEIQDLELFIAVLGYRNNCTSMCGKVLRYQGLVITPTREGHYKRLGRIFVEDEKFETWDPEKGESGQSPIITLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBP4</accession>
    <name>A0A6A6PBP4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_279617</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBP4"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="449" mass="50393" checksum="40A1DFED13CFF2CE" modified="2020-06-17" version="1">MASLGDARIIVVGAGFGGLTAAIELRRKGASVRVFESTKKLTEQGDTIQIASNATKVLAKWGNVLRAIEEDSARPPILSCKNSKGETLHNQDFPLGYDGFPNLYPSRGRAHKLVYEYAASIGVEFSFGVRVSKYFEDESHAGVYIGEEKVVADAVIAADGVHSKARALVTGVPENPRSSGFAAYRSWFPWESLEGNPLVEEIINAKEDLFWAWIGLDVHALVMTNIKMKYLAVFCTHKDTYTVEESWNFPGKKEDMLEVVKGWDERLRAVIEGIPPDRLIDWKLLWRDPAPKWISNHGRLALAGDAAHPHLPSSGQGAASAIEDGATIGAVLDRAGKNDIPLGLRAYENIRFWRACLTQRMGWELRHTWHRTDWDLVKRHPEVLEMHQPYWLFGADPEAYAYQAYDETVACLKNNKEFVPKNVPEGYRHEEWTMEDMMALEGDSKKPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBR5</accession>
    <name>A0A6A6PBR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61</fullName>
            <ecNumber evidence="1">2.1.1.220</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA(m1A58)-methyltransferase subunit TRM61</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_332044</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.220" evidence="1"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBR5"/>
    <dbReference type="OrthoDB" id="5585464at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF1">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="444" mass="48335" checksum="8C903D8E47F44BB0" modified="2020-06-17" version="1">MEFFRVGSKRLWGSAPRRSFRPALHVCCQCYRQLGSGSKRFQVGDYVLIKEVNDATHEGFLLRLGGRPTMSTHRGKVSFEDIIGARPRDVISTSTGRRYRLFEPTLAEYVLRSPRVVTPIYPSDANLIVSLLDIHVSPPSGEVLEDEGPLEILEAGTGNGSLTLHLSRAIHAANTVPPPHAVRSNPSTSQNPADSMSTYSSASEKSPDEASSSAQPSAEADAAAEAYTHWKRTRRAVIHTIDVVPKHSRHAEKVVRGFRGGMYLGNVDFHVGDAATWIEAEMQRRASSTAFLSHAFLDMPDARDRLETVSRALRIDGCLAVFNPSVTQIADCVETVRKERLPLLLEQVLELGASGSLRQWDVRAVKPRVAARDTGAKAVAAEGEGGSESGVESAGKGVGEQLGQVEYDAKDEGWKLVCKPKVGDRIVVGGFLGIWKKMADPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBU6</accession>
    <name>A0A6A6PBU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_86108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBU6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21826" checksum="84D6CFED93E22855" modified="2020-06-17" version="1">MQHLPPQSSPSLDGGDASHNHGCRTSFLFWTSGEWLVSEHTCDGLSVPLKPFSWPWCHLRRLPIWLTLRRLAAARQYDRSSLQPQYRLPAITWTWNTDRQPLVTGEGSPIKSPTANNTDNLPTARATGFNDSVILARCGDTLNRIGRESGPKNKILYKCLMFLAGYSCRGRHGGSNAPQISVRAVVYPLDSSSRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC23</accession>
    <name>A0A6A6PC23_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED18</name>
        <name evidence="10" type="ORF">BDY21DRAFT_398044</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC23"/>
    <dbReference type="OrthoDB" id="5348092at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019095">
        <property type="entry name" value="Mediator_Med18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13321:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13321">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09637">
        <property type="entry name" value="Med18"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="101"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="37711" checksum="563C99010B9861E3" modified="2020-06-17" version="1">MHELFLSALVPASRLDQIKNILAGLTAQQPTRLLERHAVYRPIRIPPPPPPAVGGSQGVAADKVARSGSANAAAAAGGGAGAGGSGAAPGRAVPGGAASVGGAGAGGAAGGRPGAGGATPTPAEAQRGRGAGGAAGGGAGAGAQGQGAAGAASGQGAGQTAAVAAARELHYLTCVREVDWAWEEDEGAGRDGGEDLDFGPWQIRFEDLPEAGRVDQMRDATLRFVTQNEVMGGDVDEYMRMVGYRFVSEFVLEGYQFVLNNVVLHLHRVLQFPAERRSSVPSAQQYQQQQLRERPRGFLPPFGSLHPLDSSGAYMLKTTVRLADGTRPDLTRAGLNELYGFRDTMKGVLELKMVQRLALDTRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCE5</accession>
    <name>A0A6A6PCE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_376496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCE5"/>
    <dbReference type="OrthoDB" id="4170557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="59"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="18009" checksum="71C3417389010C15" modified="2020-06-17" version="1">MCDLRGINPKTGKKILKGEARPGNDDEDGDVWWEEDIPETQPAVYRRLAWFCERLLEDVVGKGEKILLYASNLIEQYMVELFLTIMGISFMGIDDETNSTERSEIIRNFNAESHEARVLVTTYRTSATALNMQQTCHIAVMFSPTDSANTEIQSGWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCF1</accession>
    <name>A0A6A6PCF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_397864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCF1"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016278">
        <property type="entry name" value="DUSP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000941">
        <property type="entry name" value="DUSP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="67"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="5">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000941-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="36577" checksum="88B16175F805EBB2" modified="2020-06-17" version="1">MSLLDKVPGDLRLYIGGLFTLRRKQALQEANITHVLSVLKLPLDQGLFRDFRHMVVEVDDDDDEDLLQHFPATNQFIQEGLDGGGGVLVHCAMGKSRSATCVVAFLMQKYLISPSEALDQIQQSRPSCDPNEGFKAQLELYHRMNYPKNVEESYQYQKWLYQREVEASNVTGQAPEADKIVFEDELSSPQCASVEFELRCRKCRRALANSGYLVRHVPTGINWDEDGMTIDSSEPSPSGCAHHFVEPLSWMRSELEQGKLDGRLECPKCKTNVGKYAWQGMQCSCGHWVVPGISLTKSRVDEVKPRREATATMRIRKPPGSQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCJ3</accession>
    <name>A0A6A6PCJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCJ3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="15899" checksum="3896A8414923906B" modified="2020-06-17" version="1">MPPAALRRRRQKKTESPSQTATPPIHNADSPHRRPPASSRPRPRPLHHHHPPPPHPPRPLARSPSSPTCPPTRPTALPTRSPGPPPIPPPPPPSLPPPPPPNPEMRSRTPCRRSSPPTTACASSDSASTPSATTRPPRPTTRPACSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD48</accession>
    <name>A0A6A6PD48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_278913</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD48"/>
    <dbReference type="OrthoDB" id="406287at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="92"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="525"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="526"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="613" mass="69172" checksum="B71A5FAEAA70E6CB" modified="2020-06-17" version="1">MIAVAFPKRPAGPRPFHRRTPSSLSSVPEDLPVMTSAQDEMALTPLASSDSSAAVSSVAQKSKSQPELSTDSGLSAQVLPGDMTHGVAALQTDRTSQATSPGSKSSGLGIATPSSFSQTPRALSRRTSLSSSSQDEDDGYVPPIDRLTVFDFLENLALPSRLEKLQTSLQAQGEKVRRHQERLRSRGINAKDRVVDEWRRRIPTPADDQLDKYKKRMRDGVDRLGKQWDDSKAVTIREKISFISGVLNVFVSGYLIGAFPQYFHYWYTAQLCYFMPIRYYKYHKIGYHYFLADLCYYTNFLLILSIWVFPNSKRLFISTYCLAFGNNAVAIAMWRNSLVFHSLDKVTSLFIHIMPCVTLHCLVHLIPPSLQLQRFPAIHTIAYSEPSSPQHYTLSEMIIYATIPYAIWQLSYHFFITVRRREKIAAGRPTSFTWLRKSYAPTWIGRLVLSLPEQLQEAAFMLIQYVYALLTMVPCPLWFWSRWASAAFLATVFTWSVYNGATYYIEYYGKRFQRELEALKQDVAKWQSSPDAGPSNSSQRGGEEAEKDEGKMEKKPDNVQPMSAPAKAADEKKVGNECEDEKRRSSIEQIPLLDEKSDGTIGSGGKSTGVEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDA0</accession>
    <name>A0A6A6PDA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pantothenate transporter liz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_277400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDA0"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="61"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="507" mass="55965" checksum="EE7A84049521A9AA" modified="2020-06-17" version="1">MAATTAEKTSIELEAAKSAAEHVDNATVRRHMEAPPLVRDLTPEERKRLEAHLVRKIDFRLLPMIVIMYILNYLDRNNIATARLAGLQEELALTNPQYQTCVSILFVGYILMQIPSNLLLNKIGLPAVYLPSCMVVWGIISAATAGTQGFSGLMACRFFLGFIEAAYFPGCLFFLSSWYTRKELGFRTAMLYSGSLISGAFAGLIAAGIVDGLDGDMGLRAWRWLFIIEGVITIVVAFGSFFILPNFPRTTKWLTEEERQLAVWRLQEDIGTDDWVSSEEQTFWHGMKLAFADIKTWILMIMLFAIVSAGSVTNFFPSVVETLGYGTIETLLLTTPPYVLAVITTFLNSWHADRTGERFFHVSLPLLFGVAAFIIAATTVKTAPRYLAMMLMVPGVYTGYVVALAWISNSIPRPPAKRAAALAAINAVSNASSIYASYLYTGAPRYVMAMSVNCAMVALAVAMAITLRLVLGHLNKKLSRGEHVEGAIAVFEGQLEEEGRKGFRFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDD7</accession>
    <name>A0A6A6PDD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">EBDP4, emopamil-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_4704</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDD7"/>
    <dbReference type="OrthoDB" id="58557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000247">
        <property type="term" value="F:C-8 sterol isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047750">
        <property type="term" value="F:cholestenol delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004769">
        <property type="term" value="F:steroid Delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207:SF0">
        <property type="entry name" value="3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207">
        <property type="entry name" value="STEROL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05241">
        <property type="entry name" value="EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="7" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="15">
        <location>
            <begin position="66"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="243" mass="27299" checksum="079E242FAD3B9472" modified="2020-06-17" version="1">MAATINSTVMDVVQHPYWPVGAEINGYLANTMGVPQLLATFAGGCAVIIAVTSAIVKGVRPGMPLSELSTTLWFAICGCIHFFFEGYYSYNYKRMGGSMDLFGQLWKEYSLSDSRYLTPDSFVWPMETITAVCWGPLSFTVAWMIIKDHPMRHPLQAIVSLGQLYGDVLYYGTSMFDKFAFGVSYCRPEGYYFWGYYFFLNLFWIVIPLSLLISSVRASARAFKALHKMEKTLNASSAAKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDE0</accession>
    <name>A0A6A6PDE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_329590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDE0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19116" checksum="4EBC563DB59713E9" modified="2020-06-17" version="1">MIPDTADNHRLCRHQGSSVTLRSDVRDRGAYDRIMQDDIHRQGTTSEEAKGLRNARNFVTLNIERQMHPSPGYTYATADWYISEASQSRNPTSTSAAELAHSVEQRTHYDSGTDCSAGQADHSSPTLSPPELVDGSASGLQWQYRPSREVLEEAATTQHKWIEEEIARASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDJ8</accession>
    <name>A0A6A6PDJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase signature domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_388938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDJ8"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF37">
        <property type="entry name" value="AMIDASE C869.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025574149" evidence="1">
        <location>
            <begin position="22"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="97"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="602" mass="64121" checksum="1126B07276D724C3" modified="2020-06-17" version="1">MAWQQLSSVVLLAQLLVFASSGTASCGADNETQCVLGVDPLEEPYPIEFPPMESANTPALFPMEDCNGVTLEEATIDQLQDAMSNGLLTSVQLGLCYLNRVYQTDEYINSVLEINPDWLQIATALDAERAAGHVRGPLHGIPYLVKDNIATKDKMETTAGSWMLLGSVVPRDAHVVALLRQAGALLFGKATLSEWADMRSNNYSEGYSPRGGQARSPYNLTLNPGGSSSGSGAAVAANVVPFALGTETDGSVISPAERNAVVGIKPTVGLTSRAGVVPESVHQDTVGTFGKTVRDATYALDGIYGVDGRDNYTLAQTGHVPEGGYARFLTGKDALATARFGIPWESFWVYADAAQQATLLELVELIASAGATIINGTEIPSRAETISPDGWDWDYGGTRGRANESEYTVVKVDFYNDIASYLSELANTAIRSLDDMVAYNYANDGTEGGHPWPRGLPAFYSGQDGFLASQASRGRMDATYYQALAFTQSATRERGVDGALANADGAGDGGPVDLLLVPPDVGQTYQVAAQAGYPMVTLPAGVHGDTGMPFGLALMGTAWSEAELVRWASAIEDLQFSSGTALKRTLPNWYGYMEKNVPVLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDN8</accession>
    <name>A0A6A6PDN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_330434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDN8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="181" mass="18402" checksum="FBF85A4269A5D7D3" modified="2020-06-17" version="1">MGWAPGLLCTLVGASERMVVVVVGAGDGNSGPAWSGPGNGVAGALTYWYCGPVGAGDEAAERLKRALSSASASPSRRVWLSGQLSIEAGLSSSEKSLNSTGEGLLLLAKLSSSITSGLLSMEVSGNSSRSPNMGSGALEEGISGPFSSCMVANTAMCCQMCSRNQPQSSTLRRCGYTVEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDT9</accession>
    <name>A0A6A6PDT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP12-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_295499</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDT9"/>
    <dbReference type="OrthoDB" id="5322896at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="39627" checksum="BE3EC1EC5F2B5277" modified="2020-06-17" version="1">MDAVRRASIRAARPRPAALPPPRCLHTSPARSATPLHPTTPGPPPKAPTPIATPAQDRIARKAQQADLLRRGQAQRPQPGKPAGALQRRFWRDVSVQECDAGLQVHLDSRPVRTAAKRILTIPPSKRQLAAAVALEWDQLASAQQALKQHYIPLTSLVSRALDIRDADANGDSLVRNDAVGMMMKYFGTDTLLCWAPERGSQGSSRGDSLRQRQVQAARPILDYLTTHVWPGADIVPALEEDNILPKPQPERTRELVQGWLSALPAFELAGLERAVLASKSLLVAVRLLAEWSEELSRARATDGKAHGARFGIEEAAEACSVEVRWQTELWGEVEDTHDVEKEDLRRQLGSVVLLVGGSSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDW1</accession>
    <name>A0A6A6PDW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_8836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDW1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF5">
        <property type="entry name" value="ISOFLAVONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="32"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2462184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="34621" checksum="BC2AAF4955D08576" modified="2020-06-17" version="1">MMRIAIAGTCGLAQMIAHYVQEQTSHQLVLFSREANQQLADRGFEVLVVDYDDAQSLHYALKGVDTVISTVTGQPQINLIVAAANNRVRRFAPAEFEGSPGLRPENDPLDRGKAQAWQLLQQWRNWIPESCVFTCGVLYERFAPGGLKECHISRNSEIAGEGDYILNLRNMTADVPWCDDQGNYACIGMTAASDVGRFVVRALDMPQWPTELRMCGDRMAVHELLALAQVVRGAQFNPAQMRTTSQLRQEIPYAQYAGDTARQLRLHTLIATSEGRYDVTEPNLNALFPDIQPLKFREWLTTYWGPMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEA0</accession>
    <name>A0A6A6PEA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative Hsp70 nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_277758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FES1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEA0"/>
    <dbReference type="OrthoDB" id="10250458at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000434">
        <property type="entry name" value="Hsp70 nucleotide exchange factor fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="8">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="184"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="216" mass="23819" checksum="949845DA7814414D" modified="2020-06-17" version="1">MDPGLNELLRWSVENSDASRGDPGSQINQGRSGPRIEGLTAEALQSILGGPSDADRMRDAMTAIMSPDVDLDNKLTAFDNFEQLVENLDNANNMEVLGLWDPLVRQLQREEKELRKMAAWCLGTAVQNNVKGQEKMLSLGVLPTLVDLSLNDEDKEVRKKAIRAVSSGVRNFQPGLDEAMKTIPDEHKGNGEVDASQMDQVDTMIQSLRDKSEKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEM2</accession>
    <name>A0A6A6PEM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Transcription elongation factor SPT4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_368484</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SPT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEM2"/>
    <dbReference type="OrthoDB" id="248751at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07973">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009287">
        <property type="entry name" value="Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038510">
        <property type="entry name" value="Spt4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882">
        <property type="entry name" value="SUPPRESSOR OF TY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025023">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Spt4/RpoE2 zinc finger" evidence="9">
        <location>
            <begin position="16"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR025023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2462438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="125" mass="13426" checksum="FE65B55B0610CCFA" modified="2020-06-17" version="1">MSATTAYVGPNQQRSLRACMVCSIVQLQGRFMSRGCPNCDDFLGMRGSQDTVSECTSQVFEGLITVADPKTSWVARWQRLDNYVPGVYATKVVGALSEEAIAAAEGAGIKYIPRDGSAQEDEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKX9</accession>
    <name>A0A6A6NKX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKX9"/>
    <dbReference type="OrthoDB" id="5030973at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="32509" checksum="D7B042A099930A3F" modified="2020-06-17" version="1">MESGQLSSTAELEPEDSSGQQPSTEPKNITQCSKRAASSQFCKWGVRGDVTHLQHGMLDGKPASLIGFDFRLLDGGDGNRFSQVKVVLSFYSEPGGEASGKACETAKWPEVKVFAPKLLHGPATRTKHINAAGVSASLAGPVHFIHPQLELFKSKHVEYVRDYRLEVKGTRWSSDKRMEHDNMVVWEVRENSRQGDGVPKELRFAVLVQHEARPFVGTVKMQVTTKWGLRLFGWPWTRPHPLLFQPSAAVGVPIDVGSFGELADGHWKGLADFYGPLESCRWTEKSKLERQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLF1</accession>
    <name>A0A6A6NLF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_367699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLF1"/>
    <dbReference type="OrthoDB" id="19908at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="2">
        <location>
            <begin position="75"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="353" mass="37028" checksum="8BEC8BABCF999A2B" modified="2020-06-17" version="1">MRLSHLHLPGLTPYATANRIQDVFRSRLLAQKAAASRARRSSAAPAAHPDASASPSPSSPSLSSPSLSSPSPSSSSSPPVLLTFTPPPTYTLGRRQHAAPPQLLAQLRAPGPDGGPAASVAAAAPRGGQTTFHGPGQLVGYVVADLRAVGVGVGGWVARLEAALVRTCAVWGVRGHGGGAGVDAARTGVWVRRAGHCGREAEGVGAEEGREEKQGKKEKKAEEAGAEEGSRIWRHGQHVERARGEADALERDDGWRKIAAIGIHLRRHVASHGVALNVSTDLRWFERIVACGMDGRLTTSLRNEGVADVTVDEAAGAFAAQLAARLGLEAEPYTLPRREVEKLGVELHGLEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLL9</accession>
    <name>A0A6A6NLL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_258490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLL9"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="51" mass="5900" checksum="60B73E3C37F6B9E9" modified="2020-06-17" version="1" fragment="single">KAKRNKWTEEETACLLKGVARFGIGSWKKILSHADYSFNGRSAIDLKDRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLW3</accession>
    <name>A0A6A6NLW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sucrose transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_294897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLW3"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF76">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="508"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="59653" checksum="CD6BA5E2BBC98C78" modified="2020-06-17" version="1">MAAGVAEWRGTPHIKGSTETMRMALLTFSLIGLQFTWGIEMTYCTPYLLQLGLTKSKTSLVWIAGPLSGLVMQPVVGVIADRSTSRWGRRRPFMVGGAVVVAACLLVLGWTKELVGLFVSEPRAKRDITIAVAVLSIYGVDFAINAVQASCRSLVVDTLPISKQQLGSAWGGRMVAIGHLIGYGAGAVDLEALFGPTLGDTQFKQLTAISAMALCISVGVTCWATTERILISNGKEHHEQLGAVETLTKILKTATNLPPRIDAICWIQFWAWVGWFPFLFYGTTWVGEIYLRYEAPATTVRAHAVGAPVAGDEDTLGDIGRIGSQALIVFSIITFVASFAMPLLVKSPEHERGGGAARGFTPRPPPKLAPLMEAAEKRKPSLLTAWMCSHLLFAGSMVLAPFTTSVRFATVIVALCGIPWACQCWAPFTFMGVEINRLSSSASPTSSSSPSAHLYRRLSLGTTGGAHAGSVSGVYLGILNLYTTLPQFVGTFISWVVFSVLEPGPSAELAPDGDGEAGEAPAEEGQLGEGPRRDGPNAIAVCLFIGALAAVGSAVATRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM33</accession>
    <name>A0A6A6NM33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_404891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM33"/>
    <dbReference type="OrthoDB" id="10258825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="15"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="374"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="58241" checksum="A42E8638B24B404A" modified="2020-06-17" version="1">MFAVPGWNLSAAVKTQTDAGDKPAAGHAAATGANGTAVRQRGHKRKRAPKDRDVTDANVAELWEEIVEGKKRAGAAGPGKKEKKRRMSQDEGAADRPGATAPKLDKDGDPRNGAATPANERKSTEKKQKRSSKQTNEKKQDGPRNKANAPDPPTSKPSAASAASSAIAAVVPPPAPANTPPTASAALTPLQAKMARKLASARFRHLNQTLYTTPSADALALFARHPDMFADYHAGFRQQVAVWPENPVDAFVAEASAAAAAAVPPLPRTRGTCTVADVGCGDAALAAALGPRARRLGLALRSFDLRRPEGPNAGLVTVADAAALPVADGGVDVVVFCLALMGTNWVEFVDEAWRVLRGRGELWVAEIKSRFGRKGQGKEGRTRIGGDTKGSQQGAKGKNKRRKKRKGGEDSDSEAEDPDEDVLDAEQKESRAAAADDDETDVSAFVDVLAKHGFLLSRAAGDRAVDTSNKMFVRMTFVKAGAPSRGKNARALREMELERMRDGARGGGGGVGAGGRGQWGGPRLRFIGDGGEEDVDPVEEGKVLKPCVYKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMI1</accession>
    <name>A0A6A6NMI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="3 11">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_357828</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="3 11"/>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMI1"/>
    <dbReference type="OrthoDB" id="21243at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000050">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000044">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034762">
        <property type="entry name" value="Lys-tRNA-ligase_II_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF9">
        <property type="entry name" value="LYSINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039101">
        <property type="entry name" value="LysRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="255"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="586"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2452896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="608" mass="69527" checksum="9320CADE38219435" modified="2020-06-17" version="1">MADAPKNPIGTAAEATQNLHLDEVTGERVSKTELKRRQKQRDIAAKKAEKAASNASSAAPKKAVSEEEKEQELTPNQYFELRSRAVNKLRQTHEPNPYPHKFQVTTDLREFLQKYASLQRGEALKDVEVRLGARIYNKRSSGANLIFYDVRAEGASVQVMCQSNNAVGSVPFAQQHEHLRRGDIIGIVGHPGRTQPKNRPDGELSIFATEIILLTPCLHQLPGEYYGFKDQEQRHRQKYLDLIMNDSTRNTFITRSRMITYIRKFFDERDFIEVETPMMNAIAGGATARPFKTHHNELNMELFMRVAPELYLKQLIVGGMERVYEIGRQFRNEGIDLTHNPEFTTCEFYQAFADVYDVMDLTEELVSGLVKHVTGGYKTQFHTQHGEVFEVNWEKPWKRIEMIPALEEATGEKFPPGDQLHTDETNDFLKHVLKKVNVECTPPMTNARMLDKLVGEFIEETCINPTFITGHPQMMSPLAKYHRSNPGLCERFEAFVCKKEIVNAYTELNDPFDQRLRFEEQARQKAQGDDEAQLIDETFCQSLEFGLPPTGGWGMGIDRMVMFLTDNYSIKEVLTFPFMKDDKSAEKQPSAAKVVDIQPMPEEGIPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNJ8</accession>
    <name>A0A6A6NNJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AIM11</name>
        <name evidence="6" type="ORF">BDY21DRAFT_357152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AIM11 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNJ8"/>
    <dbReference type="OrthoDB" id="3558022at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038814">
        <property type="entry name" value="AIM11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39136">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39136:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="183" mass="20170" checksum="5B5961C5FCAA3CE7" modified="2020-06-17" version="1">MSRPDQRQQQQQQQQHQQQPPSPTPPPESTLSFFTNARSRQQFGLFAAGATFTALSALVTRRALARRMQAARPAYYQQSNRPAGAPVDGGREALEALNIASLNVASIALTLVGGGLWAFDVSSVEELRWRLRRGLGLEAKGKEEDEDEFEEWLAAVLARKEGKERGPGRTAARGRADDGLEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNK3</accession>
    <name>A0A6A6NNK3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_356188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNK3"/>
    <dbReference type="OrthoDB" id="5817083at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="9">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="365"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="550" mass="60457" checksum="DA05DCB37C2EE390" modified="2020-06-17" version="1">MASLPPRPASQSRSSPRDETVDTVAQQQRDEDSGSSPSASRSDPQTVVLDGLGTQGSDKVTPPTAVMASSGPTEPTEPTAEPRKCWICFTDENEEGAPASEWRTPCPCALTAHESCLLDWVADMESPTSNRSTGTHKGPILCPQCKEEIRLARPRSVVVEAVRAVERLGSLLVIPGVLFVGVGTLYQAAVVHGATSVYFVFGVRDGYRILAPLYTAPGQIAHENAVPHLVELVRDSFRHWRLYGGLALIPPVLVLSRTSIADSVLPILPVLFFATSSNQELDTGQALRNWPPSASLSFALLPYIRGLYNTYYERVWGAHERRWLREIQPRSGNSDREGDRRNGDLRLQDDAEGVLEINVDLNIINEGWDREDEQDDEEEQRREEDQDAQQPQGAAEEPQRDRGPAHPLHAPPIDLPEAVHGDHAAAQPGPPQHPRPQAEPRNDDGRQANFLVPAARAADSLLGALAFPAIAAAAGELLRMALPKSWTTSQANGRPAGLLQMRWGRSIVGGCAVVVLKDAIMLYVRWKIAQSHRRRRVLNYDKKKKTWVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNU6</accession>
    <name>A0A6A6NNU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear transport factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_382259</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNU6"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05227">
        <property type="entry name" value="AR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000191">
        <property type="entry name" value="Methylglyoxal reductase (NADPH-dependent)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025436736" description="Nuclear transport factor 2" evidence="7">
        <location>
            <begin position="28"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="NTF2" evidence="8">
        <location>
            <begin position="340"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="457" mass="50161" checksum="A12F1B778F51F62B" modified="2020-06-17" version="1">MTRVLLTGGSGFIAAWVLDLLLQQGHSVVTTVRSRAKADAIKAKHPEYGSDKLSFAIVPDIAVEGAFDDAVKSDPPFEAVLHTASPFHYNVTDIQKDLLDPALIGTTSILKAIKKSAPSVKRVVVTSSFAAVFDPAKGDNPGYPYSEADWSPLTHEQALENMVAGYRYSKTSAERAAWDFVEKEKPNFTLSTICPPLVLGPTAPWLASLDNINTSNARVRDAILGKFKENGEIPPSGVYLWIDVRDLAIAHVKAMDVPDAAGKRFFTTAGYFSNKEIVELIRKNFPEYADKLPPPDVKGGDYPPGGVYKYDNSRSKEVLGLEFMSLEKSVVDLVNSLKAVGEQFVEFYYKTFDENRAGLAGLYRDTSMLTFESSEVQGTASIVEKLTNLPFQKVVHQVATLDAQPTQNGIVVLVTGALLVDEEQKPMSYTQLFNIIAESPGSYYVFNDMFRLVYSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP33</accession>
    <name>A0A6A6NP33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF7732 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_292931</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP33"/>
    <dbReference type="OrthoDB" id="5425547at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056634">
        <property type="entry name" value="DUF7732"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091:SF1">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24866">
        <property type="entry name" value="DUF7732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025674513" description="DUF7732 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7732" evidence="4">
        <location>
            <begin position="114"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="279" mass="29005" checksum="8D7A5B3B91EA690E" modified="2020-06-17" version="1">MRILQYFTLTLATVNAVNALAVSHDVQDISRRDAEPCGSLLECYAPSLHNALEKRRGGGGRSGGSSSSSSSSSGGRSSSSSSGSTPSNARGSSNAGGRTSSGSGVTPRFGGGRFYGGGAAVPYTAGRRSPRGIVPFFLPLALLAFFPGLWLFGAYAYPWTQPYTFVNETLANDTFPNGVNQTRPVLCLCERYQVCGCDEVDDRDAYMRDIIGNGSYAALNDSLVTVADVNGTVTIAINGTLPNGTTASGGDDDAATSLVASLSGYWVVAGIAVYAVWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP90</accession>
    <name>A0A6A6NP90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock factor-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_382343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP90"/>
    <dbReference type="OrthoDB" id="4159489at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.430:FF:000006">
        <property type="entry name" value="Heat shock factor binding 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="73" mass="7831" checksum="24F01D59CE24A10C" modified="2020-06-17" version="1">MSNQESKDQPSPTSAAPAELTAVVDELLNQLSTKFSSVSSEIMEKMDEMSRRLDNLEATIQAGSQLGGTKGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPJ0</accession>
    <name>A0A6A6NPJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_388158</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPJ0"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000002">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_uL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="6">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="98"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="29784" checksum="EA92B391319AC6EB" modified="2020-06-17" version="1">MSPQKHAGTVKTSVPTQDSILVPETLLKKRKSQEKEREARAAELEKKKKANKEKRKVIFKRAESYVKEYRDAEREKVRLARLAKSEGSFYVEAEPKLAFVIRIKGINKIDPKKRKTLQLLRLLQINNGVFVRLTKATMEMLKIVEPFVAYGYPNLKSVRELIYKRGYGKVKKQRVALTDNAIIEEHLGKYGIVCMEDLIHEIYTVGPNFKQASNFLWPFKLSNPNGGFKPRKFKHFIEGGDLGNREEHINNLIRQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPS2</accession>
    <name>A0A6A6NPS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_366776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPS2"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16837" checksum="05389589B7619A26" modified="2020-06-17" version="1">MSFSAIFPPLLYATTGQQSLPKLVSGVRTSENTGRLLVRAEIHTRGSTIYEIATGRQPFCEKPEEQEREVEQLIKEGKHPDVSKLPLGDVIAKCWKRDGFFNSAADVAEEMTRSTARPVMKFFQRRTGGSRRPDLVYESKIYLFNALNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPT0</accession>
    <name>A0A6A6NPT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_124415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPT0"/>
    <dbReference type="OrthoDB" id="2140489at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986:SF1">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="252" mass="28330" checksum="4E98AE57F5A495F9" modified="2020-06-17" version="1">MASSVKVSNAASPNFLHANSRPEDSTSVTVRDHKTVTCSSDELKFEAGASQQIVWGTNEPISSSSSSSSNFLISSPYNEEGHLLNLRDLDTPDRLLALALTTMKPIRPDYATAPYAESFNWGSIMSTLKTLGELESFAWAEPRVYYVVIFRSRLSPDTDVARLHELDYLSQGEAAMSGGLLKYWFGTRDERLQNLATCLWRSREDARRGGAGPWHRRARGAGKDLYAQITFSTHRLVISEGFENWHFEKWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQB1</accession>
    <name>A0A6A6NQB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_387821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQB1"/>
    <dbReference type="OrthoDB" id="7289984at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF32">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="27303" checksum="521F848181EF32D3" modified="2020-06-17" version="1">MASKKIILVTGANSGVGYETSYTLADASPNNHVIMGCRNTTKGAKALEEIQARKPAGTLSMLEVDISNDDSINAAAQKMAADFGVLDVLVNNAGIYIEDKRDRRTDLLETFNTNAAGPVVLTDALLPLLKKSKDPRIINVTSELGSMTKRADPNAGGYNLNCDEYRMSKAALNMASVCMNEWYKSWGAKVWSYCPGWVVSDLGGRANRQFKIENGADSPETSAQGILDIVEGKRDGEAGLFVMRWGRRSNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQB9</accession>
    <name>A0A6A6NQB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_126803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQB9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="18294" checksum="9B3692CCB260C64A" modified="2020-06-17" version="1">MTPANSKLAAHITRARSRMREVRARRKLIQPSTCFGCSLRWLSRNGLASGQLSPGAAPRAPPARHATSPAVPSRPVPYALLRILRTVCFGLPVAMGPRSSLHPSPRFVREPPLAQTDVILALAGWSASKQASRQASIVARLFPPTHRARIALPAHFVPAFELHRLITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRX1</accession>
    <name>A0A6A6NRX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_353628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRX1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="18327" checksum="E6107E52BBEA89EE" modified="2020-06-17" version="1">MCGRSILAVGPSTVLYLVRPIPERCRVASTEELPSYWAVWLESDVLHGGRATEDGISWPSPPISTFLGTYPPKQRTECLDDARFVPTRAHLTRTLPLVTGPDRDSCAVELAAHVSAGRSRCLPACATGLLDSGSSASLSRAIRSTYGHCISSDPTSRSADYIRSYSRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS63</accession>
    <name>A0A6A6NS63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_353460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS63"/>
    <dbReference type="OrthoDB" id="4187030at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17826" checksum="E8FD9C55B096E44A" modified="2020-06-17" version="1">MARSARAYTLIQRRSQPGRALSSRLKKPQATTFATFQTPANLTSEQTTQARPSAEKCLCGRPHEYIRCYYFNPSIRPQGWILSPKVEQLIRLNIKKLRLDAHKELEDLLKELGTISYMKGQTHAYAVDTTDIADTQVSAADSHLAAGTAFSPPSFYHVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT57</accession>
    <name>A0A6A6NT57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT57"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025491160" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10286" checksum="37FF05A12D80C9BB" modified="2020-06-17" version="1">MAVDDHLFLFFALLCLTHGPCRSFPTASTAHNAKTLCPRGASLTVKFFFQGRRTYLEFPLLPSSIFTRSRIARPSPAPLSLPRLPLWRRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT60</accession>
    <name>A0A6A6NT60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_97331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT60"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17424" checksum="5687FC93FD3804BB" modified="2020-06-17" version="1">MHGGQCCSGLVLLKERWDKGTTVLDLSFTAGLTSLRKYKYELLNERDAGRFNGNGGPGPLYVNLMPPRCIHSQINTMCRVHVPRNPFSRGRRQGLRLDKTSTPGAAVDRLQSSTRAVPRGGAKMPLCDLSRGLAPSTVAEVLVAASRTATPSGRRQARHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTC5</accession>
    <name>A0A6A6NTC5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dehydrase and lipid transport-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_373709</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTC5"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="5">
        <location>
            <begin position="42"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="223" mass="24305" checksum="BC01439DF8659C25" modified="2020-06-17" version="1">MSSKPPSLHPHRTFLPNPFASSTSTEPNGSIPLQSISATRTLPYPREQLYEIIADVNAYSSYLPYCRCSEVTAWTTMLPTSTSTTTSHNDGQQSQHGRRYPAEAILEVGWSAFTERFTSRIVCEPGVAVSAVAGKDAAEFGGAAADTSLLIRCRTKWKFEDVPSARGAEEDANTDVSLALDFVLANPMYAAMSAAVAPKVAGIMIEAFERRARELLGERGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTK1</accession>
    <name>A0A6A6NTK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Myosin-like coiled-coil protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_95537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTK1"/>
    <dbReference type="OrthoDB" id="425555at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="298"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="369" mass="43208" checksum="764C504E915B35C3" modified="2020-06-17" version="1">MDKINFLTKRYTDLLADMKKLERECTRSKKKADQLQKEKDKQGQELNRISGMKDNLEKLSRNVTKDNKKLQEKVKAMEENQGRVNDELHARLMRVAEPVEQVINSKETPQVPVVDIETDKLFKEKFKSFLEQYEARELQFMSVLRSKELEIQYQMAKLEEQKKAQEKESTKSNKLTRQVSTFSKTEEELRSQLNIYVEKFKQVEDTLNNSNDLFLTFRKEMEEMSKKTKRLEKQNQNLTRKQEATNRNILEMAEERTRTEKELETLRKKNMNLEKLCRGMQAQGRGQVNTNQLNERDVDVDETASEFEYDEDDEGSGDYDDDTEEEALEQRPRAFGPIPPPPAHQATSSGKENGQAGRPLVNQTNGIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTK2</accession>
    <name>A0A6A6NTK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_102401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTK2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16257" checksum="36C3FF8AE38F30B9" modified="2020-06-17" version="1">MNVKSFGIPTSDTGRVWTIRSSPDTDLPHTTAAPNPPPQLPNQTRTPPPDQLPYHANVPKRLVTVAAARRCRNQRQTQKACLICAREPCPPSSVSVSRVERAGEPKSRPGRIKTAAVPIRHPSGEELLPRVMQVSAVISRVDNCASLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTN7</accession>
    <name>A0A6A6NTN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_79525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTN7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16844" checksum="142F3EC9E487889D" modified="2020-06-17" version="1">MKPSRSPVSGIGSLPSVSPTPCFFNCFPAASVRSPSCSSLDQQLAQQNGGRYQGPQVGRFHTHAAPCAHLSLSLYLILRSWFSKRLGGQHTELASICFNFSWPSLGLSDQSRLASTSTHDAVRTFPNITLTRQPPLALLSILSVYHGQPCVDECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU17</accession>
    <name>A0A6A6NU17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mo25-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU17"/>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="369" mass="43079" checksum="21580CC7374A8DD5" modified="2020-06-17" version="1">MAFLFGRSREKSAVDVVRTTRDLLQRFHSISLQNTPAVEKVANDTGRNLALMKVMLQGTTEVEPNPEQVLQVVELILQEDVLRELILNVKLLHFEARKDAQVVLTNVLRYKRPGDLAGEPIAIHYIVKDDPGLVRQFCLGYNARESAFPCGAALREALKYDAITALVLYDEPTDDGRPRDLDRIDPTVPTSEEGIFWNFFNWIHQREFEVSADAFNTFRDILTIHKQLVATYLQTNFETFFHKYHTAFIQQGSYVTKRQGLRLLGEVLLDRANYNVMTRYVQSAEFLKIFMTLLRDYRKMIQYESFHIFKIFIANPTKSPEVERLLINNKARMLKFLPTFLDDRRDDDQFLDERTFLLWQVNQLPDTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUA2</accession>
    <name>A0A6A6NUA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_397015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUA2"/>
    <dbReference type="OrthoDB" id="2159786at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007224">
        <property type="entry name" value="TIF_Rrn11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04090">
        <property type="entry name" value="Rrn11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="453" mass="47360" checksum="39CD2169FED44946" modified="2020-06-17" version="1">MLTPSTFAPLASSAGPSSLRSSRYRPSHKRKHSAMHSPTDSDSSSSTSTSSVSSSTSTSTTPPAHPFPHARSPRTKPPSLPHLPSGPSAHLATLSPPLFAMAAAPTASGPQPPSRRRPAVPTAPLSALLHAALLRRDWAVAARAWAALLRAQPGLDVRKGGAWGVGAEVLLRSGGDDEGGGGGAGEVGEKGLRRARAFLERLVVQFPAGRGGVGGGVEAGAGVGAGAGADWGARDRADAWTFYEALFGVWIREVVESGEAARARARARAKARARDHWPGDGDPPPNMDPPTSATAATTPSPALASPSGSESSESTPSPNNRRHGLHPLLECRILSTQHRAAAAIAARLDELFAAGPPFDRHAPLLELRANVGLWVADLLEERAEAAELGEEWSGEEVEEEGILEGEEGAGGSGGEEEEDGGEERRRAWMEEARGERERAGEALRMARRVREGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUD4</accession>
    <name>A0A6A6NUD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_373434</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUD4"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="515" mass="58442" checksum="DDCDAC09D1DA2F7F" modified="2020-06-17" version="1">MSTSLFDVTAQLGSKLRPTSVEGILNLTGAVLVAVVVQYVASVFYAAYFGPLSHIPGPKLAGGSWLIKSYYQRQGTLIGWMTHLHEKYGPVVRVGPTEVSFITGESAWQDIYGFHHDASKTGKYYLKDREFFSITPSGVWSMIAEDEANHSKERRLFSHAFSEKALREQEPLLQRYVDLLQMRLHEESESGKLLDLQKWYNYTTFDIIADLAFGESFECLSQKSYHPMVVMTFKAAAAISMKNIMSHFPIAARFSSLFIPQETLKKRIEFYDFTKSRVERRLAMDTARPDFTTAILKHSDTNRSLSRQKIYANMGLFMIAGSETTATMLTGTTYLLLMNPDIMQKLNAEVRGRFKSANDITIEEVNKLPYLLAVLTEGLRMYPPVPIGFPRVVPRGGDTISGVYVPEACKVYVSQYHANHSPRNWVDPEKFAPERWLGDERYAGDNKANYNPFSFGPRNCLGKNLAYAEMRLILAKTVFSFDMELAPESENWFSRNKVFSLWEKPPLMASLTAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUU6</accession>
    <name>A0A6A6NUU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Indigoidine synthase A like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_350519</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUU6"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="7">
        <location>
            <begin position="801"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="862" mass="90612" checksum="F734052277AAB634" modified="2020-06-17" version="1">MALIGGIVRCSRPSVFGRWCRRSNGAHLSQTRHLTTNNAFFKVSEEIREAINSKKPVVALETTIYTHGFPYPENVALASHLESVVRVNGGVPATIGVLDGVARVGLNPEELIRLTSSAGNPDTLKVSRRDLAYATGLHLTQRTLNGGTTIAGTMVLAHLAGISVFATGGLGGVHRGGHVSMDVSADLTELGRTPVAVVVGGCKGFLDIGRTLEFLETQGVAVGTFADGRAENEKGKVPFPGFWCRDSGLTSPFAIRDEREAAAMVYAQNEMGLSSGILFANPIPEQHEIPRAEMEVIIEEALVLADRAGAAAMGKDNTPFVLDAIKQLSKGTSVKANRELVSANVARGTLVAREVAALQREGGWEAKTESGDDVFGRPRDQSQVGGTDRSRNGLCKADFPVSLPDSVLSPKPAPTSSHPLPSVLVAGALALDYTCTFTPFTSLPSAPTISPSPQLRTSNPSIIRQTLGGVARNVARACHLLGTPTRLVSAVADDLAGLVAKAELARQGMDGDGITFVSGGRNNGAGLGTAQYVAVNDAKGELVVGMADMRILEDESGGIGTQESSCSAIVRMVATALQPNSATAVPTPPTHLILDANLPSKTLHTLLRLAKSSFEPLTTVLEPVSAPKSTRLFPSSSSLQLPLFPDHVLDLLTPNTSELSALHSAARSTGAFDRPEWWRVIDALGIPSSGARHEFERALAHDVSAALLTSDVEGRMESLRIASELVDRGVPQMAVQLLPFAPVVLVKDGRQGVVLAMLLRREDERLSDAGQAGWVVARAAATSVVGLGGVYLRRFTVPEKVLEEDVVSVNGVGDTFLGAVVSGLAKGKKVEDTVGVAQKAAVVTLRSEEAVGIGLAELRGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV15</accession>
    <name>A0A6A6NV15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_289561</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV15"/>
    <dbReference type="OrthoDB" id="5852090at2759"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000001">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="14">
        <location>
            <begin position="133"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="15">
        <location>
            <begin position="255"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2455418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="398" mass="43446" checksum="1E17B974895B0E80" modified="2020-06-17" version="1">MVSDVNGTAAGAASGVDRGSFLFTSESVGEGHADKICDQVSDAILDACLSEDPLSKVACETATKTGMIMVLGEITTKAHLDYQKIIRNTIRDIGYDSSAKGFDYKTCNVLVAVEEQSPDIAQGLHYEEALEKLGAGDQGIMFGYATDETPELLPLTIQLAHKLNAAMKAARLDGSLPWLRPDTKTQVTVEYDHDVGAVVPKRVDTVVVSAQHSEDITTEQLRKEIMEKIVKKVIPAKYLDDRTVYHIQPSGLFIIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYLARWIAKSLVHSKLARRCLVQLSYAIGVPEPLSLFVETYGTSNKTESELVEIVRNNFDMRPGVIVRELDLAKPIYCQTAKNGHFTNQDFSWEKPKTLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVA3</accession>
    <name>A0A6A6NVA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_387251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVA3"/>
    <dbReference type="OrthoDB" id="2192830at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="291"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="532" mass="61555" checksum="6EB78A49A4A21997" modified="2020-06-17" version="1">MDYRASTGNLAFYDDAPPPRRGPPGGGGGGPERWDREKFESFTRREPDGDRFRYAHADAYGPRGSRHELLLDDRDVERGPRGGVFVDRDRYYELERSGGGPRPTAPPPPPRRSRPDFLDEPLPEEVARTAVAPYRRRSVVDREYDYAAPAPPRPAPPRAPARPQFLRRTSSLDTFDRRPAPRYEDRRDDAWRPPAEVPIPLPIRRRQASPPRRSRAGTRDRFYEDDYESVRYADDRSPEVREEDYRDVHIRREKSRHRSKRRGARSVKSERSSSTSSFEEVEPVRRAPASKKGRTKMPKRLVHVKAVVELGYPFEEDEDFIIVLRALHKEQIDEVISISEKYRSTSTYRYEEPRPVDPAPPPMPPPSMPPPPMEQPPPMAMPPPPPPPPPPESYHPHYPMAPGPAPPPPPPPATSTTSVSTVRSPSPPREFYEERVEESNHIGGPLTVVQHPDHHHHAHHLHSMPRTEREIRNEIRELEQERRLLRLEREPRETEIEFVERRGRSRSRSRDREVVRVERDRKGRMALVRSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVU9</accession>
    <name>A0A6A6NVU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_395194</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVU9"/>
    <dbReference type="OrthoDB" id="422427at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF1">
        <property type="entry name" value="ACTIVATOR OF STRESS GENES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="706"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="802"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="886"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="946"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="805"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="887"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="917"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="960"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1097" mass="115597" checksum="B24CDC63D00E0F29" modified="2020-06-17" version="1">MENSPAATAEDTPGSAPAGAAHPDAQWDTASTSPPTLEADDGPASASGAEADDDNAAATATARTAAGAPNSKPAAPVQKRRRVTRACDECRRKKIKCDGKNPCTHCTVYSYECTYDQPSNRRRNAAPQYVEALETRVRRADALLRLVLSYPIDLDDPDIDASLQRGALPPRRPDHQRPPPTATGGPANSSGSDDQLESMVKAVGNLDVDEQGKWDYHGHSSGLSFIRRMREQFGDVISAEGNATPFVKSRPMSHVFDSPKSNVDSPQDVVPGADLPPKEIARQLCDYAINDASSMLRILHQPTFYAQLDRIYDTPLEQYTNDQNTFLPLFYAVLSLGSLFTKDASGDTENRDYEDAIEEGFKYFKASRQLLDIADCRDLTSLQAILYMILFLQCSAKMPTCYSYIGVALRSAIRIGLHRSFDNNFHPIEAELRKRVFWVIRKLDIYMGAMLGLPITLCDEDIDQDYPSEVDDEFITEDGILPMPDGRVCAMEAFNSHTDLVKILAKIVRAIYPLKYAAGIGKQRSSDATYTISYSKIREIETDLRQWEERLSPKLKPGGDVPVLIMRIQQLLRMSYAHAQLLLYRPFLHYVSPTRRSKDGDKRTYACAAACVSVSRNIIHITAEMKKQSLLVGGYWYSMYTCFFAILSLVYYVLENPDSYNSNEIFRDANMGKETLASLSKRSMAADRCSATLKVYFKRLPERLTRSRPLEHAKKRRAAASPYPTPQSAPTPPEASPTAAAGDNALPRMPPRSTAFPSASAAAATGQPPFAVGPGISPSFPLEAKFASSPTTQTQQHAFDFSAGAGAGAGTGAGGTPPTSAPYPAGAATGAPAMAPFVQGRGLGPGQQGFELGDLNDPSLTDLSAFMFPSTDPFAYPNQPMMAFEDGFGGGGGGGGGGGSSGGGGGGGGGGSGPGSASGSASPFAATFSPQHMAGIDAGAVSMPGQGGAMFRSSPEGRQGVCGGALGAGSGGGGGGGGSDGGGGGGRSGNGGGGDVTAQPFNPMLNSMPMYLAQGCGGLQNHHQAAQRMAAGQHQQQGQQVGGCGAGAGGNAAFGHGGFAGGQGGPGHDAFEDLFAGEEWPPGVFSEGVGGGGMGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWE5</accession>
    <name>A0A6A6NWE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_55285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWE5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="18496" checksum="11D221A18855A909" modified="2020-06-17" version="1">MSLRPARTVSGTACIASAPRRTLSCPNAAHAYLHTLHDQTAGCGLLFSACRCRLLSGRATNTAVASGGTVQSTATVERGLESGRLPRLPPAVTTGQQDVPASPSMRQSVVGEIARSGRCSSEQPCKLVSREKWPQSSMRCPELTGSIITFSFGCPAISKTRGRGLSLIRQGRAGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWY9</accession>
    <name>A0A6A6NWY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_348445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWY9"/>
    <dbReference type="OrthoDB" id="10261807at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Quercetin 2,3-dioxygenase C-terminal cupin" evidence="5">
        <location>
            <begin position="167"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="265" mass="29671" checksum="E03A3051ABF96948" modified="2020-06-17" version="1">MTTDNRLKITKRPWDSRGFANHGWLYTFHTFSFASYYDPKHEQYGPLRVINEDRVQRGTGFGTHSHAEFLIWSYVVSGELEHKDSMGHVEKLRRGEVQFTSAGTGIRHSEYNRNRDEDTHFLQIWATPNVRGLRPTYATRTFTDDMKRDKLVKILESLDRHDGSEEESSPIPAHADISQYASILSPGQSVEHALVADGDRKIYLHVVMTGKQQPASGGAKIKIGDVELGEGDGAYVDDAKGPGSITIESVGDSPAEFLLFDMGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF5</accession>
    <name>A0A6A6NXF5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDY21DRAFT_51829</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000026">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000047">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1075"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1115"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1158"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1195"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1223"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1266"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="249"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="1044"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="626"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="626"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="626"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="628"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="628"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="721"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="762"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="785"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="900"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="901"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="992"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="998"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1018"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1021"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1022"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1022"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF2456485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1371" mass="153725" checksum="BF85F506C5DB0324" modified="2020-06-17" version="1">MAGRPPEGSGTGPSPYRQGGDDNLLLDLDDNVRGPYYSGGRPPVNDEDMLRRYDIDDNDTPQPRPSVSYDDFVGGGPRSAASGPGSNLPGGPGAPAAGGVGAQPYFSAGDNRLYSQTSDLHNYQRYSDMDDLPEDDRSMQGAYYGGGGVDGGAALGHRRLGSKGGNRNSILSLGGGLMGRAKNMLGMGPEYSEMDLPLTETGTHPAHTDTVESPEEPSKPERKKFDAGKFKFGFGRQKVDPATLGPRIIHLNNPPANSANKYCDNHVSTAKYNVFTFLPKFLFEQFSKYANLFFLFTSILQQIPNISPTNPYTTIVPLIIVLLVSAIKEQVEDYRRKTQDKSLNNSKARVLKGSSFQDTRWINVAVGDVVRVQSEEPFPADLVLLASSEPEGLCYIETANLDGETNLKIKQAIPETANLVSPSELSRLGGRIRSEQPNSSLYTYEATLTMHAGGGEKELPLQPDQLLLRGATLRNTPWIHGVVVFTGHETKLMRNATATPIKKTAVERMVNYQILMLGGILIALSLISSIGDLIIRQTAEGRLRYLFIAGTNPATQFFSDIFTYWVLYSNLVPISLFVTIEIVKYYQAYLIDSDLDIYYDKTDTPSNCRTSSLVEELGQIEYIFSDKTGTLTRNMMEFRQSSIGGIQYADEVPEDRRATFEDGNEVGIHDFKRLEENRKSHPTSENIKQFLTLLAVCHTVIPERDDEKTGSIKYQAASPDEGALVEGAVQLGYRFTTRKPRAVAIEVEGQELEFELLAVCEFNSTRKRMSTIFRCPDGKIRCYCKGADTVILERLWEGQPIVEPTLQHLEEYAAEGLRTLCLAVREIPEQEFQEWYQVFNTAQTTVSGNRAEELDKAAEIIEHDFTLLGATAIEDKLQDGVPDTIHTLQTAGIKIWVLTGDRQETAINIGMSCKLISEDMTLLIVNEESSEATRDNLSKKLNAIKSQAAGGIELETLALVIDGKSLTYALERDMEKLFLDLAVMCKAVICCRVSPLQKALVVKLVKRHLKAILLAIGDGANDVSMIQAAHVGVGISGMEGLQAARSADVSIGQFRYLRKLLLVHGSWSYQRVSKVILYSFYKNIALFMTQFWYSFQNAFSGQVIYESWTLSFYNVFFTVLPPFVLGIFDQFVSARLLDRYPQLYQLSQKGVFFKTHSFFSWILNGFYHSLILYWASEFIWRYDLPQGDGKLAGHWVWGTALYTASLATVLGKAALITNIWTKYTFIAIPGSMIIWMIFLPVYAYVAPLTGLSMEYIGVIPRLFSSPVFWLMGLVLPFLCLLRDFAWKYAKRMYFPQSYHHIQEIQKYNIQDYRPRMEQFQKAIRKVRQVQRMRKQRGYAFSQTDESQARVLQAYDTTRERGRYGEMASSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXW0</accession>
    <name>A0A6A6NXW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_47956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXW0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="17027" checksum="EE07880CF2154D2E" modified="2020-06-17" version="1">MPTPAPPLSSQVQPATSNRSSAEPAALLFALLSAYRHSRLYSVIYRNVGELERLRWGRRDLTGRARAFELLIHTVATSLLLRFLRGLRDLVTPSWNGGIAVRARAGSPFNVYVTLIVMACTVDLFDTDPSSRFHVLLLFWIVHFITFSELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY10</accession>
    <name>A0A6A6NY10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_287489</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY10"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000547">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="206"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="661" mass="71577" checksum="E1C48391BCF1A773" modified="2020-06-17" version="1">MPCSVLGKRTRSVTESSGKSSRKERGRKRTQFVVGNDENENPFITRQTRSSARLGHDDAPSDAPSDGFQSAGKENNLSCSVPAKHGAFESRVALTPGKINSHFKSTKFLTTSGAKSVRTTSQTPTRYHDALLADTSVTPKRRVGLSGKSLTPRKSQTPATPKTAPSVYNEARQLFSQTVLATDLVGRESEKDELEVFVMDRVESMSSGCIYISGPPGTGKSALVSQITRQFEGMKVVKSAYLNCMSIKSGADIYTTLLDDFGCDATGLEASPMETLREVFFKRESVYLVTLDEIDHILDLDLDCLYKIFEWSLLPSNSLALVGIANALDFTDRFLPRLKSRGLKPQLLPFMPYSAAQVGRIITSKLKSLLPFGSTAPRDFTPFIHPTAVQFLSKKVAAQTGDLRKAFDIARRAIDLVETEARDKQARDATTQQPPTPTPSPSKTPLIANMNLSSPPGAHSPIKTPSRKTPLTSALGDLTIETAPRATISHIARITATVFGNGAQQRLLGLNLQQKAVLCALRALENKKKETAHHQQRQRIATHAATAAVVAPTIRELYNAYSSLCRHEDIFHPLSATEFRDVVASLETLSLVAMVEGKGGSFATPTTPSKRGRAKGGFATSIIEERRVASAVGAGELETALNGVGGRILKRILIGAGLDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYB7</accession>
    <name>A0A6A6NYB7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_322952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="200660at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="615"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1300"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1326"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1374"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1384"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1414"/>
            <end position="1438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1505" mass="165317" checksum="180B43378CD45A9D" modified="2020-06-17" version="1">MAEDDDDGDDDGGGEEAAPRAEGPRALRFSQPLNWRAGRAIPVAELHKRLGALCNELRPAEQDEIERASLLPVAKELASHQLLSHKDKGVRAWTACCVVEVFRICAPDAPFSASQLKDIFTMIINHVFPALADPTNPWNTQHSFVLKSLADVKSIVLLCDIPGANNLILHLFEVCFDVLSGGTKADSGEELSKNVEHHMTELLQYLVDESQGLPGEVVEVILAQFLRADPRALAGTSSKGKKGNSSQHDERQSTLLLKEAPPAYNMAKNICNFSPEKMARYISQYFSSVIVDASTARELHQQHQPRHGKRGAVPDSDEVEDDLPRGPTAEEWEESQKAHRLLRELWRSTPSVLQDIVPQLEVELAAEHGSLRLLATETLGDMVAGIGAAGPPAPPTLDPAAYPSQSLLPPAADRGQTTYNFLTTPSSPHSFPSRHPQIYQAFLSRRNDRAPAIRAAWVTGVGRILMTSAGGVGLDADEEQALLRYLADMLVDVDERVRLAAVRAVERFDFEGVLQKLGSRGGVAEPGGVLANLADRVKDRKHGVRTEATMLLGRLWGVASGAIAEGSDRVAALLGPIPSKIFEAYYINDTEINALVDTILFESLLPLKFPPIKSKGNPPSFSSQQQLSNGGGGGGSQRARRSAAGQQNGDAAGQQEDPDRIRAERILILVRGLEHKAKTAFFARQGQQSGMAKFVDAYLAKCEDYNGGVMESNEKETKQQLTRLVDALAKYLPEPLKVSDDLWKFAKKHDRRCYQLIRFCMLPDSDYKRVYNAMKEFTKRIEEAFGHSSSVLDTFKILIYRAGVLVYNKSHVPAIIQYSRTNEKDLGPAAHDVLKEISTHKAEVFRAHVQELCQSLKARAPTSAKPNWTGAVDDLKACSGFARKFPEEMPKERAFTQALFGFALHGVPPKAAKYGTQILLTISERKAMHARDLVAKCTKGWTFGKDNFLSKLAALSQVMLLTPQEIEDDVDGVTDLALNEVLLKNRVEPEDGDPRWSDAVDDEMAAKLWALKILTNRLLAHEDDGTLKAVAERPFRLLNRLVADGGEVSKKGSTPPHHKARLRLAAAQHLLRLACQKRLDHLLGPRAFNQLAVVAQDPLLPVRTGFVRKLMKYLGQDRLQHRFYAVIFLLAFEPDARLKEGVTTWTRARAAEHARRKATVLEAAFARFLSLLAHHPDFDPDDEDGLADFAQYILFYLRCVANQDNLSLIYHVAQRVKSATPAADQPSINLYILSDLSQEVIRRFEEQRGWSMQAWPGRLRLPGGIFAPLPGHEAAVAVANAQFAPERLVERLDDIVRDSLRRHASKRARTTGPGSSPAAAKDKGARRAKRMARTPRRARGARRGAAGDGEDDGAGLAGPSSADVAARRRSGRHAGGEQKRYVELSDEEQEEVDEEEEEEQEEEDVQMGEAAASSEDDSQDGEEEEERSAEEEESGAEDASEKAAADGAEEDELTSPSPRLARGKANGTSRARGPVPVKAKGGVKKPPPKAPVAAAVGTRRSTRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYS4</accession>
    <name>A0A6A6NYS4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_372195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYS4"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="83"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="523" mass="57343" checksum="3D8A4350FE97F865" modified="2020-06-17" version="1">MSVNADNSSTLDDPNDEKDLGPEKDVRPDTPVDLETGVSQRQDAAVDGVDDEPADPNVVWWDEPADRDPHNPMNWSARRKWGTIAILSMLTFTTPLASSMFAPGVPDVMQEFKNTNQQLATFVVSVYILGFAFGPLLVAPLSEMYGRMPLYHISNVLFVVFTVACAVSSNMSMLIGFRFLAGCVGATPVTIGGGTIADIMPQEKRGGAMAMWILGPLLGPVVGPVCGGFLVDAQGWRWVFWLLAMLGGLFGILTLIFGRETYAPALLKRKAKRLRKETGNENLRSKLDTGISHRELLARSIVRPTKMLLFSPIVASISIYVSIYYGILYLLFTTFTFVFEQQYGFSSSTVGLTYIGIGVGMFIGLTILGPGSDKILRKHKEAGREMKPEHRMPLILTVPAAIAMPVGLFIYGFTAYYHTHWIVPILGTAVIGYALMGCFMTSQTYLVDAFTVHAASALAANTVLRSIFGALLPLCGLDMYDALGLDWGNALLGFLAVALIPIPIIYWKYGERIRTSKRFKVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ27</accession>
    <name>A0A6A6NZ27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ27"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="325" mass="35644" checksum="15C0594450364B7A" modified="2020-06-17" version="1">MITTAQLREYLDASGVEYTSVAPLDGGTANFVWRFEYENGGTAIVKHAEPFVKDNRAIAFPAERMDVEAMVLSSLPPVLAPADAVRMPAVHRYDAANHVLTMDDGGARTLKEAYTSLDVKPFGDALGKWLASLHEATPEHDLGEGGNLAARAIYRYSYAHLAGALEAFGQDVGLGGRVDSEFGSLLQSDDEVVCHGDFWPGNVLIGADCKMTIVDWEMVRRGCGATDVAQFAAEAFLLDKFRGEKGLLPAFLSAYRAAAGKPSREFFKRVAIHFGTHVAFWPTRVRWGTREETAECVRLGAYVLQHALDDDWTWFEQGVLTALRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ48</accession>
    <name>A0A6A6NZ48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ48"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="71" mass="7652" checksum="042BCF555F0BF7C4" modified="2020-06-17" version="1">MCLTSLFCRGPRRPRLSQEPLRSFPGKKGACPPASARAPFGKKAKKPSRVAGRASKRARCGVSADASPRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZG3</accession>
    <name>A0A6A6NZG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_257923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZG3"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000173">
        <property type="entry name" value="Heat shock transcription factor Hsf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="111" mass="12997" checksum="A3D1035A9A5DF3AB" modified="2020-06-17" version="1" fragment="single">KKGIPPFVQKLSSFVGEPKWSHLIRWSDSGKSFIVVDEDEFAKKLIPELFKHNNYASFVRQLNMYGFHKKVGLSDNSMRASERKAKAPSEYAHKYFRRDRPDLLWLVAKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZG7</accession>
    <name>A0A6A6NZG7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_345670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EMC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZG7"/>
    <dbReference type="OrthoDB" id="124397at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="5">
        <location>
            <begin position="113"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="254" mass="28493" checksum="5F1FC117B3C85B15" modified="2020-06-17" version="1">MSADLLSPPPHLPPAAALRLSQEAPRVLGNSSSKSLPYPFSLLYAAESPETWIRYENLLLACLRTGDDRSARLCLERLAERFGDPNQRVKALRGLYQEAVAPDNNALEAILKSYEKEIKDDPANMPIRKRRIALLKSMSKVPDAIAALVELLDVSPTDVEAWSELADLYLTQKLYPQAVFSMEEVLLITPNAWNAHARMGELLYISAISTTNNDGGTTRILSESIKRFCRSIELCENYLRGYYGLNLVESSYWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZL1</accession>
    <name>A0A6A6NZL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_322478</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZL1"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF2">
        <property type="entry name" value="ACID PERMEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="561" mass="61295" checksum="C03875BA2EEF2D65" modified="2020-06-17" version="1">MTSVPVLTGDKLASSSQAGSPTYDESLTGFSAAGDNDNNAESHDLGSNDDGDEDTVHRRRRAEKKGSSFDQRDMFRMGKIQQLRRNFRFVSIFGFTMVLMATWEAQLSANIFGLINGGTGGLIWVYIGTFTGFLAAIASMAEMASMAPTTGGQYHWVSEFAPRRAQKFLSYIVGWLCVLGWQVGNTSIGFLASSQILGLAVLNNPSYTIQRWHQTLLIIAINTFCQIFNSFLASRLPLVEGIVLVLHIFGFFAILIPLWVLGPRGEPRAVFFTFTDGGGWGNVGLSCLVGMLSPVFSFIGPDSATHMSEELRDASRSLPRAMMATALVNGGMGFVMIVTFCMTMGGDIEAILATPTGQPFIQVFYNATKSNAAASVMTGIMIIMAIFGNVTNVATSSRQVWAFARDKGLPFSGVLSYVRPGWDIPLNAVLLSYAIAVLLALINIGSTAAFNIITSLGTGALISSYIVSISCLILKRLRREPLLPARWSLGRYGLPINIFSVLFLTLVFIMSFFPQTRKVTPESMNWNVLVYSAVVTFSIAYFAVRGRFRYVGPVEYVRKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZX5</accession>
    <name>A0A6A6NZX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine biosynthesis bifunctional protein ArgJ, mitochondrial</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Glutamate N-acetyltransferase</fullName>
                <shortName evidence="9">GAT</shortName>
                <ecNumber evidence="9">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">Ornithine acetyltransferase</fullName>
                <shortName evidence="9">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="9">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="9">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">N-acetylglutamate synthase</fullName>
                <shortName evidence="9">AGS</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="9">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_32965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9">The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="9"/>
    <dbReference type="EC" id="2.3.1.1" evidence="9"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZX5"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006592">
        <property type="term" value="P:ornithine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.340:FF:000002">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.70.12:FF:000002">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2330.10">
        <property type="entry name" value="arginine biosynthesis bifunctional protein suprefamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="entry name" value="ArgJ beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003802">
        <property type="entry name" value="PRK05388.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100:SF0">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5025738628" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025738629" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="9">
        <location>
            <begin position="239"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="9">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="9">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="9">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="478" mass="50772" checksum="0FDD616D719957D1" modified="2020-06-17" version="1">MALPTSTAQRFLVRASRQLRHYSAPGTGEIPAAKAKYVPKSGTYPKGFLAASEHVGVKPSNTRFDDLALIVSETPCAAAAVFTRNKFQAAPVTVSREVLRRREGDGIRAVVVNSGCANAVTGKGGVEDAIKMGEETDKCFEDGEGEGDDGKGARTLVMSTGVIGQRLPIRKIVRKIPSAYESLGSTHAHWLRAARAICTTDTFPKLLSRTFTLPSSPDTPYSLAGMTKGAGMIHPNMATLLAILCTDAPVAPPSLHALLTAAVDKSFNSISIDGDMSTNDTVVLMANGAAAATTTTTTASNGRPTPRTIAAPDDSDPDYVALRETLTRFAADLAQLVVRDGEGATKFVTVRVANAASYGDAKRVASAIARSPLVKTALYGKDANWGRILCATGYAEGADSVVPDQTSVSFVPGDGSEELKLLVRGEPERVDEARAAEILKEEDLEILVRLSDKEGEEAVYWTCDFSHEYVTINGDYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P016</accession>
    <name>A0A6A6P016_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="7">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_345000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="7"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P016"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1580:FF:000004">
        <property type="entry name" value="Purine nucleoside phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006054">
        <property type="entry name" value="PRK08202.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904:SF9">
        <property type="entry name" value="PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="9">
        <location>
            <begin position="33"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="95"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="319" mass="34421" checksum="4709EA3338593AB4" modified="2020-06-17" version="1">MDDDLTSPSTYKRASETAENILKDLPEQLRAPKVGIVCGSGLGGLAEAIEDEPKVEVPYKGIPNFPQSTVQGHAGKLVFGLIGPAKTPVVLLVGRAHFYEGHSMELVTFATRLCRMLGVEVMIVTNAAGGLNPEYNVGDIVCLNDHLYLAGMVGVNPLRGPNDESIGVRFPPLSDAYDLELRRRAHIAWRKLELDSSRGKLHEGVYAFASGPTYETRAECRMLRGFGADLVGMSTVPEIVVARHSGMRVLAFSLVTNRAVLEPGLRGDDPLVQGMSAGGLAEFLSKGKANHEEVLEEGRKAARDMQGLVKEIVGDLYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1E0</accession>
    <name>A0A6A6P1E0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_30044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1E0"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01806">
        <property type="entry name" value="Ubl_NEDD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038738">
        <property type="entry name" value="Nedd8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="10165" checksum="61EA11A8F8E037C1" modified="2020-06-17" version="1">MLIKVRTLTGKEIELDIEPDYKVSRIKERVEEKEGIPPVQQRLIYGGKQMNDDKTAEEYKLEGGATLHLVLALRGGCGAGCGATTDDAVAAGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1H5</accession>
    <name>A0A6A6P1H5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_31050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1H5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="17247" checksum="643A99B2EC952FB9" modified="2020-06-17" version="1">MRLCLPPPGRSMRLGRDGINVRAVRGLGLTGMGMARLFSNTRRPPTLIRGATLLGILLDGLAPGVHRRMFPVILSLCQSLFLSLFHLSFATLFSLFIPFSSCSSLALSTVSRSRWIVEKRSISNLQLRVHFPDSRRNFARSVRRLQTRTQRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1R3</accession>
    <name>A0A6A6P1R3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1R3"/>
    <dbReference type="OrthoDB" id="3642826at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="758" mass="76024" checksum="5327AABBBA9F83A8" modified="2020-06-17" version="1">MVHMIWAEESYNYTAATVYLEVDNATNATTTMTISQRPQSDYEAWAYTNIYLRSGGTNATTREAAVSAAVTYNIDIVTETEYTTTFPWFRETLSPTYGTIEEVYTETFTWPTQYVIIPGWSVWRWTKDDAQISANSTSALSGPLTTGPAMCDAVEDRQFQPFKPESYIVVTMPPEMEPLATWTDYVNCATDSDVWDPCMWWVHTNIATLPSWAWPSDLTDTESCTGYIRAIPTAKVPISSVTSTVVSYRPGPVSRTTAGGPAPTTPPPPPRPEPESHPAPVPDDAPPTGNPENEPLSHDAAPLPPNEPSAAPPPVAPSAPPAPITPLAFTVGSSTFTANDAGQFVVDGSQTLSAGGAPVSVGDTLVWQVPEGTAIVVGGTAQAVPGTPAPVPGTPAPAPQEQQGGAAPGAVVTIGPSSVTANGAGAFVFDGQTLRPGGPAITVDGTPVREIPAAAATAGGAPILLLGGTLQPLTGNAGASFTLGAATYAADAQGRFVVSGHTLAAGGPGAVVSGTAVALVAAGTAVVVGPAAGAPGPSSTQLLSPPGGAAAAAQTSAHVLTLPAAAGGATLTADHWGGFALPGGPTLRPGGPTLRPGGPPVTLGADGDGDGDDAVVLSEAADGAGLVVVAGARTSSVALGTVALAYADVVGIILGAVREGWGEAVAATAAAGASETGADGGAEEDEEDEEGRERATRPSGSRSAAAGYTWPGLSSSTGGAAAAATTTSKGGGGRRVAGSEWLPVVGLVTSLLVYVLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P235</accession>
    <name>A0A6A6P235_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Lysophospholipase NTE1</fullName>
            <ecNumber evidence="3 16">3.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Intracellular phospholipase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_284942</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the NTE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="3 16"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000062">
        <property type="entry name" value="Lysophospholipase NTE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1090.10:FF:000007">
        <property type="entry name" value="Lysophospholipase NTE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1090.10:FF:000018">
        <property type="entry name" value="Lysophospholipase NTE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 15 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 15 16" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11 15 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="693"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="852"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="19">
        <location>
            <begin position="1231"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="268"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="506"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="15">
        <location>
            <begin position="1235"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="15">
        <location>
            <begin position="1262"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="15">
        <location>
            <begin position="1382"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="560"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="573"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="15">
        <location>
            <position position="1264"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="1382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2457837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1534" mass="168844" checksum="373E2EEDF6EFF373" modified="2020-06-17" version="1">MSAESALTSPAAASVAVAAHSLSGSTPSAVATVTHHVAAPSSFGVLGRALLAVLRVVPGLLYWVITFATITLPTWLFTLFSMSLTFTLNFTTLLIIFLAFGSTVSWIVRYRFLNMYTRLPPEPQRKEPQLELFPDTQERDSKPGLSNYLDEFLSAIKVFGYLERPVFHELTRTMQTRKLIAGETLLLEEEKGFCLVVDGLVQIYVKSTRDPAPSESDVLQTSEDDDEDVREHAQGYQLLTEVKNGAPMSSLFSILSLFTEDIKLRHDEDDDTGVESGASSAGLGQPKTPAPDSAPAETPISTARSPFYGPQSPRNAKLKRKGQSAVAASPTANGQLPAVPPLSLDANAEEPRPSRDGGAGGKSRSRSRKVKSAHPDIVARATIDTTIAIIPATAFRRLTRVYPKATAHIVQVILTRLQRVTLATGHAYLGLTSEVLRTERLMNKYTTYDLPGFLRDSALERLKEKFAKERERIGAEEGAKGIALHNPGIGRRRRRSSAGLRREVAAQAHLTTRPKSSGGDKNGEPIHKITSPDSDRSGVSAGDLLTNTHVPNRGGRHSRLSFSQPYQTPSPARRGDNRTPLDERNFNPFTSSVNRQMSQRQESLDEDFVFRESILDCMFKAIGLTNIKNPLPRSESVEQSPRLVSFDSRRQRAVFSNAFGFIDPYEASVDADTESVASVSMSTFSGGGSHSILEELVNDVEIVFFPKGSVLVEQGERNPGLYYVIDGFLDVGIPSEDSDSDTGVLEPRSAEDHLSSFDLLGESAFKGAASGSSRAAPLGKPEDGRKKKRLHRKTLFLTKPGGLAGYLGTVSSYRSFIDVTAKTDVYVGFLPRASIERIVERYPVVLLTMAKRLTTLLPRLILHIDFALEWVQVNAGQTIYDQDDESDAIYIVLNGRLRAVQEGEDGDARAVGEYGQGDSVGELEVLTESVRPASLHAIRDTELAKFPKTLFNSLAQEHPGITIKISKIIASRMRALTEDPMNEHGKERYAAVGRYKATSTVNLRTVAILPVTAGVPVVEFASRLVNALTQIGTPNGVVSLNQSAILNHLGRHAFSRMGKLKLTQYLADLEEKYGLVLYVADTAVKSPWTETCISQADCILLVGLAEGSPAVGEYERFLLTTKTTARKELVLLHSERYCPPGLTRRWLRNRMWINGGHHHIQMSFRTAPEPVHPPTRRFGSALKQRVQVLQAEIQKYTSRKVRQTPLYSADTPFKGDFHRLARRICGKSVGLVLGGGGARGIAHIGIIRALEEAGLPIDIVGGTSIGAFIGALYAWDADVVPMYGRAKKFAGRMGSMWRFALDLTYPSVSYTTGHEFNRGIFKTFGNAQIEDFWLEFYCNTTNISKSRSEIHTSGYVWRYVRASMSLAGLLPPLCDEGSMLLDGGYVDNLTVAHMKALGADVIFAVDVGSLDDQTPQQFGDSLSGFWAFLNRWNPFSSYPNPPTLSEIQARLAYVSSVDALERAKTSPGCRYMRPPIDPYGTLDFAKFDEIYQLGHRYGKQFLSQLREEGILPVTEETEEKKNLRRTMAPRRASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P294</accession>
    <name>A0A6A6P294_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="12">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_342959</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ISN1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="12"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P294"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028836">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="419" mass="47071" checksum="4555F7F38A547BDB" modified="2020-06-17" version="1">MTTRYRVEYALKSHRRDQLIEWIKGLLAVPFILHSQPTAVFEPHRETHDQMAMNAHRRYAEIMRDVEEMINDHIAHQNAGAAHRSKLKLIVPSVSNFFTPLALHDAFVYQDARRHISSRRFVPPSFNDIRLILNTAQVTSLVRSGPIELITFDGDVTLYDDGASLTDENAVIPRILRLLQRGTRVGIVTAAGYTEARRYYDRLHGLLDAIHVSALPPPLRNNLIVLGGESNFLFRYSDGAEALLEHVPRREWLLKEMVAWQEADIGTLLDVAEGALRDCIANMHLDAQLIRKERAVGIIPKDGKKFAREQLEETVLVTQKILEVSDVGRRLPFCAFNGGNDVFVDIGDKSWGVLVCQRYFGGIAGSKTLHVGDQFLSAGANDFKARMACTTAWIASPAETVGLLDEMEELGELAERKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2B2</accession>
    <name>A0A6A6P2B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_214196</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047657">
        <property type="term" value="F:alpha-1,3-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070600">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11323">
        <property type="entry name" value="AmyAc_AGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000058">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000073">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000052">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025401191" description="alpha-1,3-glucan synthase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="2436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2045"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2069"/>
            <end position="2092"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2104"/>
            <end position="2125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2146"/>
            <end position="2167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2179"/>
            <end position="2205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2225"/>
            <end position="2245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2257"/>
            <end position="2281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2290"/>
            <end position="2309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2334"/>
            <end position="2354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2361"/>
            <end position="2380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2408"/>
            <end position="2428"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="64"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1670"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1814"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1682"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1738"/>
            <end position="1750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2436" mass="272616" checksum="0CC87CD58779D859" modified="2020-06-17" version="1">MKAIVSWIVIAGVGSVSGLRYDGDHIDHNLNQNETAVSPLDYWGKWPDHEFHPSPENWRFPFYTLFLDRFVNGDVTNDDINGTVFEHDIMSNQLRHGGDVAGLVDSLDYLQGMGIKGIYIAGSPFINAPWGADSYSPLDMTLLDKHFATITQWRAAIDEIHRRGMYVLFDNTMATMGDLIGFKGYLNDTTPFTLEEHEVQWKSNRHYLDFEWSNDYNETCEYPRFWLETGFLVGSDVTDRMNGCYDSEFDQYGDTEAFGVFPDWQRQLSKFASVQDRLREWRPTVLDKIKHFSCITINMLDIDGYRIDKALQVTVDAQAEWSEHMRECARAVGKENFFIPGEITGGNTLGSIYLGRGRQPDMLPENITQAVTLTNDSDPGYFVRDHGKSALDSGAFHYSIYRSLTRFLGLDGNLAAGYDIPVHWVNGFNNMLLTNDFINANTGKFDPRHMYGATNQDVFRWPTIRNGTERMLLAMFVTTIHLPGIPLLLWGEEQAFYVLDNTADNYIFGRQAMSPALAWQNHGCYSLGSKQYFQWPIESGLDGCNDDSVSLDHRDPAHPIRNIVKAMYHMREQYPVLNDGAFLQLLSNQTRDIQYPGSNGTVTETGLFSVLRSQYPDVQDLSEEGERGNQSVWLLYHNDNATVNYEFDCSDNETALIAPFDEGTTVKNLFYPHEEITLKASTKKLGIDGSAEFNGCLDNLTMAMYEYKAYVPKDVFIGPPPMITKFVPGHDARVLSTVAPGKQEEVDVEFHFSAEMDCESVTNSLIINSTTEDLRIARLVEDSVECSVVDTEIDNTYVGGIPTTWKWKGRLENVSNGVHALTIDNATTFDDNPVPTNAKDRFLFRIGQPDNPMVFAREANYTRALLHKHEGNDTLFVSHKAAGADKWRYSLNWGSSWSEWADYHGGNDTLENQEWSGTSRQRWDHEHIVLQYYTKAGGSADVMQHGDLDRDNDPPRRFPHLFAHGPFNQYGFDAGLRNEFHLEENGRWEYHFMGEWPAEFQVNVWGMNPDGQPDQTGVFGDVDGDGVLDKLPPSSLAQLLVNLSDVPPAPYLAWRMSLNDGNYRYDLIPVGNRWQQLVLYVLLWIVPVLTGGLAVWLYTQSFYAVKFNEVGVTEKKSLIPDTIRKAGKTLFEKRRSGETISLVRTPANNSAVDLPQSSAGLGKRRCVLIATMEYDIEDWGIKIKIGGLGVMAQLMGKNLGHQDLIWVVPCVGGIDYPVDRPAESMRVKVLGKAYEVQVQYHTLRNITYVLLDAPIFRKQTKSEPYPARMDDLESAIYYSAWNSCIAEAIKRFPVDLYHINDYHGAVAPLHLLPETVPCCLSLHNAEFQGLWPMRTDKEQKEVSEVFDLDLETVREYVQFGSVFNLLHAGASYLRVHQKGFGAVGVSNKYGKRSFARYPIFWGLSKVGKLPNPDPSDTAEWDGKLPNEKDIKVDPVFEAGRPELRKQAQEWAGLNQDPDAELFVFVGRWSMQKGIDLIADVFPPILEQNPKVQLICIGPVIDLYGKFAALKLGKMMEKYPGRVYSKPEFTALPPFIFSGAEFALIPSRDEPFGLVAVEFGRKGALGVGCRVGGLGHCPGWWATVESTSTTHMLQQFKQAIEEAIASDQPTRALMRARAAKQRFPVAQWVESLEALQSSAIKIHEKERKSKGRPTSSWSRKSLELPWHEVPDDIAVPPVPGSLDTPNGPSAYNSPTATGYNTPNGSRSRAQSMSRRSDDANGLNLSPSPEGNSPPRESRQSLTQEEPSSSGLKRTLSLGYKAGPGHDVAENGRRRLRKRNPSSVIGVAISEAETEDDQAVDAPREDLEYTLTREEAEAGRRNNGLLPSFPLASAQPGTPRAVSIPTTPNPTTPAQGPGDSLLAPPSAPFMHVSFNQSRNSVLSLDSVTGGKTDFKLQKVDPFFTDSTGEFYSDFGKKLDDLNGKTSESHLCIEEFLVKSERLWFDRFRDARLGRTQPSTPATSIYRGKKGASTTIEPMTASEPDEDFDEFLLGKDYKPPNGLKKYLQIKVGDWPLYSFFLAFGQIVSANSYQITLLTGEVGQTAEKLYVIASIYLGTSIIWWFLFRRLKSVYVLSLPFLFYGLAFFFIGLAPFAGTNLSKVWVQNVATGLYATASSSGSIFFAMNFGDEGGAPVKDWVYRASTIQGTQQIYVVALWYWGSTLAAATASGRKPQTGIASQPVMAAIAIPIAVLFWAVGTIVFAGLPDFYRQRPGKVPSFYKSLARRKIILWFFATVILQNYFLSAPYGRNWQYLWSSNNAPAWAIALLVFTFFIGVWGLFLWIFSILSKDHSWILPIFAIGLGAPRWCQMLWGTSSIGMYIPWASGHVGSALAGRSLWLWLGVLDTVQGVGLGMILLQTLTRIHVAFTLIAAQVLGSVATILARATAPNKLGPGDVFPDFSEGAIAGLSKFWFWIALAFQLVICVGFFKFFRKEQLAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2M2</accession>
    <name>A0A6A6P2M2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_363182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2M2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="22920" checksum="10CB3D3442CDFBFA" modified="2020-06-17" version="1">MAPNCRRREDRKTGAKRYKGYSKASDEKCRYASEKSLPPKPNNRKRSRRAEDSHVDRSPKRPWNRSVESATRAALIEHDTFDQRATAQSRHIQYWVENDIWSPECFEPDIIEQLIAKESLSESSRKRSVSSFAEARQEKSPPYESADYEQELERKGSHIIPDGTLLDDVVFERICEELRSRNEAKILKNATPLIVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2R6</accession>
    <name>A0A6A6P2R6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome oxidase c assembly-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_256950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2R6"/>
    <dbReference type="OrthoDB" id="4205486at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029208">
        <property type="entry name" value="COX14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14880">
        <property type="entry name" value="COX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20734" checksum="EF9F11787E638937" modified="2020-06-17" version="1" fragment="single">SAADATRFTSTGPYAGSKFAGSQFAGRSTIVRLPEDGGKVPEGETPAQKIARLRAMADKQKMLRNEMSTFDKVILRGRVWADRAHRFTVYCLLGLGGMAVVLGAVSIVDMAIYSRQKRLEYDQANKLAYQTALHNAIAAKEAGVASEEALELIRHDAEVAAAEKEFQEQPSLWARTKMRLFGNLRKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P305</accession>
    <name>A0A6A6P305_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_342393</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P305"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025388407" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="396" mass="43727" checksum="658BBCF47139D8F5" modified="2020-06-17" version="1">MVSRSVLEGLFASLLGLSLLTAPSFAGPISKRAKINDLADTALENVHKILSGNLTDGSTHTTCTSENVAVRKEFGDMSEEERADYVRSVNCLLNTPSRLDPEMYPGAVNRYDDFVVLHMNMTPTVHMTANFVHWHRAYVWAYESALRDECGYQGYQPYWDWSKYPDPLESVMFSGSDTSMSGNGEYIEHEGHRLGMSSDPVPPGKGGGCVQSGPFANMTVNLGPVMVSLDIEVPANPQSDGYGLNPRCIRRDIGDFFTSQYLLPDQLATHIESTDNVLTFQTTLQTDTAEAYSFHTGGHYTIWGDPGGDFLVSPGDPMFWLHHGQVDRHWWIWQNQDPEARVQQYEGPTVMMDPSSPEGKLTDVQELAHTAPQGLGVLTSGDLVSTTAGPLCYVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3E9</accession>
    <name>A0A6A6P3E9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_318718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3E9"/>
    <dbReference type="OrthoDB" id="5415741at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="76" mass="8282" checksum="E8B4AB5464AB1E50" modified="2020-06-17" version="1">MALNTDIATRALIISLKSASCSKTTAKISTITGVPKRTIQAIFSRAVKQGFDLNTTLIIVRDEYVIDTPRSGRLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3R7</accession>
    <name>A0A6A6P3R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphotyrosine protein phosphatase I superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_283738</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3R7"/>
    <dbReference type="OrthoDB" id="3388at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="5">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20186" checksum="B113BBCCF23A18D3" modified="2020-06-17" version="1">MSASSATPPSKPVSVLFVCLGNICRSPMAEGVFQHLTKPPGETHHPRVDRIDSCGTAGYHAGDPPDSRTMSTLSDNGITAYRHEARRFDPDDFRAFDYIFAMDRSNLSDLKRLRTRFVKHEAVAEEELGKLLMWGEFNGRTAKAEEVIDPYYGGKDGFDIVFEQMTRFSKHFLKHLEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y9</accession>
    <name>A0A6A6P3Y9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1989 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Y9"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018959">
        <property type="entry name" value="DUF1989"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31527">
        <property type="entry name" value="RE64534P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31527:SF0">
        <property type="entry name" value="RE64534P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09347">
        <property type="entry name" value="DUF1989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1989" evidence="1">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="231" mass="25704" checksum="B7723BAFAF563EE9" modified="2020-06-17" version="1">MRVLEAATDDSVPSISRTIVPAGHGYSFAVSAGERFRIVDLHGQQVVDFMAWARTGRRCHLDEKVSMAYTRYHHYGATPSTGDYLWTNRDRELFRITDDTVRVHDMTFMACFPELYEKRGLRGHRACASNIAEAMAPWGMKNHLEVADPFNLFQNTPLYAIKGNLLSSRPGDFIEFEALDDAVVAISCCPYDLDGFNGGKITDVAVMTGFRLSPRKPENASLESDSTPGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P403</accession>
    <name>A0A6A6P403_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_204684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P403"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41637" checksum="0790CCC58C52898F" modified="2020-06-17" version="1">MAMAGDARDALRELIGERIQGLFPLGWAVHVNVDIQMTPPESLPEHAPIALTEDRAKADGREAMQPPSGRKRSFSQVSGISPETHRGSFTVLNLRENMSSVSKQPRRKYSPEEHERFVRNRRHGVCERCKRRKQTCTHNMQSPKTPDLSPVALHSRSRPIAAKEKSTSVDTSPAAFFPDTTCRVEDLVPPPQHPTRHARTRSQPNNHLNAPRAPGGGNADMNASQANSIFPFGSQAVPKQSGFCFGMFGSTALHSRPTYVQQYTGEPPFHWEIPSLQSPPQIEYSLGPRITHNGCAQLDNVGDPPTTGSGLDGPSNFPLQDPTGTPFLSFVGYSDLVPPLNPSLPGSDWPRPYSTGTDAVLGDQVTFPDTPGQSSQPRTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P456</accession>
    <name>A0A6A6P456_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_207137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P456"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="22888" checksum="BAFDD1BEB9BD6F91" modified="2020-06-17" version="1">MYAFLCCLLSARDLSCDVHRHNMPKCSVVLRTTYVLVAFTLLIHLQLLKGCAPGMRPAFPWSMPRVVAARPSLSCGAADQCGELALDSRPVSAERQPGARRTFDLPPAANLRCHSPLAAPLPEGIRATNPPSLLSRRGDFSSRSDRLHRRDHSQHESLFVLISSQELQSVENWGPAPPSRRLIVDPVTVSDPADRPNVPVYVRRRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4F9</accession>
    <name>A0A6A6P4F9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_283570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4F9"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="69"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="406" mass="44021" checksum="B0DFC0F8CFB1B42A" modified="2020-06-17" version="1">MLDPFPLSASPVLSRLVTPLATRLSLPTLPLHVHEVLLAAGLYHLTYTTLSPFFSSRLFPRAYSAFPRRTRLNWDVHVVSLLQSTIINALALWVMWTDEERAHMDATERVWGYTGASGLVQAFATGYFVWDLVVSAVYVSVFGVGMLAHAVAALAVFSLGFRPFLNFYGPTFILYELSSPFLNVHWFCDKLDLTGSRLQLVNGICLLASFASARLVWGSYQSVRVFADIFATFRAARTRAVDAAAAVAGPLLDDAGAAQTAVVAAQAAVDAVPVWLVAAYLGANLTLNGLNWYWYGKMIATVRKRFPPPWGTKRVGGEGEKGRAAGEKEGRGKAGREGEWDGEDSVLVEGVEVEDLMEGVEGLEGDGALGLGTAMGMGIGVGETVVRTEGERDGEVEKTEVRRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4H0</accession>
    <name>A0A6A6P4H0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="16">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_410810</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="16">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="16">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="16"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4H0"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17942">
        <property type="entry name" value="DEADc_DDX18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000379">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000460">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044773">
        <property type="entry name" value="DDX18/Has1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 16" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="185"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="375"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="637"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2458642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="664" mass="72901" checksum="B91BDFC019DD7401" modified="2020-06-17" version="1">MAPSVIGTKETKKRKRKHGSGKHASNGTTTATATVPAEQAPTAPVSKPAGSKARKRAKHEHSSDKEEAVSEPEGEIDNVDGEEQDEEDLNKQLRELAAQSGSAAVENGGDAADAGPNGDKDNEVAAPATANGAGAEGSVGDLPVSLPRLGAEPQKFAELNLSEKTMKAIDGMGFETMTEIQQRGIPPLLAGRDVLGAAKTGSGKTLAFLIPAVEMLSALRFKPRNGTGVIVVSPTRELALQIFGVARELMAHHSQTFGIVIGGANRSAEADKLSKGVNLLIATPGRLLDHLQNTKGFVYKNVRALVIDEADRILEVGFEDEMRQIVKILPKEGRQTMLFSATQTTKVEDLARISLRPGPLYINVDYRQEHSTVEGLEQGYVICEADVRFRLLFTFLKKHKNKKIIVFFSSCNCVKYYSELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNAKHGTLICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGAKGKGKSLMFLQPSEVGFLKHLKEARVPLVEFEMPAKKILNIQSQLEMLIGKNYYLNKPGIRGVEKVDDVTHAENRLLTCSLGIKSAKEGYRSYLMAYASHSLRSVFDVHQLDLVKVAKSFGFQTPPRVDITLGASLSRDKKLGGRRAYGSQPRQVKRFQRKRADGERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4K5</accession>
    <name>A0A6A6P4K5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS multidrug transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_319242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4K5"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000297">
        <property type="term" value="F:spermine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF182">
        <property type="entry name" value="POLYAMINE TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="37"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="476" mass="51830" checksum="FA23A6E068CA56D2" modified="2020-06-17" version="1">MQEQRAPQPNVIEVLDWNGPNDTENPHNWPLATRIYHTVTISLVAFIAALGSSVFAPAVPQAAEDLRVSTTVAIVGVSVYVLGLGFGPVLAAPISENWGRSPVYKISLPLLMLFTLGAGLSKSISSLIVCRLFAGIFGSPVLAVGAGTNTDLYPLYTRAISTSLFLLAPFSGSALGPVIGGFASQYKGWPWTQWCIEFAALAAFVLLLRTRETYKKIILQRRAKRLGARGPTSNSPKGVAAAKMLLTVTLFRPVHMLFTEPIVAFLSLYNSFAFAVLFTFFAAFPRIFMGTYGFSESQAGLPFVAVFVGVMLSFVSSFTLDRLMYMRLHRQAVSEGKAHIQPEHRLYAGMLGSIGLPVGLFWFAWTAEKGTHWIVPIIAAVPFGWGNLSIFTSSAMYLADTYGSMYAASALGANGLLRYTLSAAFPLFTVQMYNTLGTGWATSLLGFVSVGMLPIPWVLFKWGPRIRARSQYPTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4L3</accession>
    <name>A0A6A6P4L3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4L3"/>
    <dbReference type="OrthoDB" id="409121at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017771">
        <property type="entry name" value="Cyanamide_hydratase_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03401">
        <property type="entry name" value="cyanamide_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569:SF1">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="60"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="234" mass="26002" checksum="F3E29595411AAC2A" modified="2020-06-17" version="1">MSDQKGQYGWTAVPRSQSSFFKIYPPKDVIPLKVADIMIPVSPAVTKVSEYAKANLSEETYNHSMRVFYYGAALIKQHFPHFATFTETYLLACLLHDIGTTPANLQSTFMSFEWYGAYLSLDLLQKQCGAPQAQAEAVCEAIVRHQDLGETGDVTALGQLIQLATVFDNIGMNPSLIHSETIKHVTAAFPRKMWSGCFASVIREEIGLKPWCHTTAIEGFAEKVEGNALMKPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5P3</accession>
    <name>A0A6A6P5P3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Argonaute siRNA chaperone complex subunit Arb1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_283057</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5P3"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033167">
        <property type="term" value="C:ARC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018606">
        <property type="entry name" value="Arb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09692">
        <property type="entry name" value="Arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="82"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="541"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="600" mass="68254" checksum="1E1D99977969ADED" modified="2020-06-17" version="1" fragment="single">PFQVEYYFSDENLPYDEHLLEKCGGVENKPVRIKHICGFPRMRKFKPFTQVVEALRRSAFLEVCSGNTIRRRVPLLPDMLVHSDDSEVEGGEKDEDKDKDNRKKEEKRGLVPPPKRMNQKTQKDTGMLKGSTGFEEFFAEAPLTPEQVKEESGLYDEKKPITERLEIAIHRYKQKRKFWTFAGQVFNRFLKYGGVEAKERQFTGPMDEVLTQNKDKGEVAQLLATHQLDPELDEADTWVVDFEGVAKGFFSSVYPVFTSSVTPRMTREATGILRNFYNYLMYHDVCPEYADSLVAARRICDLADRELPRVRRAGLRLPGAFNVSCSELHNGYWSGMFVGKDNSFIHGRSDWAEDEAVADRELDEEEGLEDGEETTGAPRVCQALGPIQARELTPMGLEVAHVEMPNERTLRFYEMARLNLRTDFKVGRAMQPVGKLHCRPWTPPAFVKYDLPVEEAAKQDLNSSDELLVFLVETDVLRTCFVGMKLDAVVGRMVNGMPFLDQINNTYASFYTYLPNELLSTPWKAPEMTARARELEMTGPDGEIVKRDEVAGKKGENSDQEDPAKVGGGLDTMAADGLLDLTDQDIGEMYRMPGWERVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5W0</accession>
    <name>A0A6A6P5W0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5W0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="21198" checksum="9E08874F1B12753B" modified="2020-06-17" version="1">MEDPSVPLSGVLSRLAFRLSRMDGRSDPSRALSATPFTGCYVHKLVHAGRRLTCRCSCFVWFAGLMSRQSSRPIDGRKLAWLLAAFDTLRLKPASLTVKVEPHCSHATITWSPNFRRLIPDSTLPGKASNVLRRPTERHTCDQRPQLDPGDWRLGAQYHVPPLAQSSGPMPIIKSGHETTQTARHSQKVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6J9</accession>
    <name>A0A6A6P6J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Anti-silencing function protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_189515</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with histone H3 and histone H4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ASF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6J9"/>
    <dbReference type="OrthoDB" id="29755at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1490:FF:000001">
        <property type="entry name" value="Histone chaperone ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017282">
        <property type="entry name" value="Hist_deposition_Asf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037759">
        <property type="entry name" value="Histone_Asf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="151"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="33529" checksum="14B91043E796D4AF" modified="2020-06-17" version="1">MSVVSLLNVNVRNNPAPFSAPYEFEITFECLEQLQKDLEWKLIYVGSATSSEHDQELDSLLVGPIPVGVNKFVFEADPPNLTRIPSSEILGVTVILLTCSYDGREFVRVGYYVNNEYGDEALNAEPPAKPVIEKVRRNILAEKPRVTRFAIKWDSEESAPAEFPPDQPEADAAEDDGTAYGADEEDEEEDEEGENGKEDGSGVGSAAAAAEAKPAGEDAEMGGTEEEGAAAAGAAAGAGAKGAKGEDDDAGSEDLEAESSEEELEEELDEVMDGDEEMDMGEDEAKGGPQQGQGVVVQGQGQGQQQQQGPDVMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6P6</accession>
    <name>A0A6A6P6P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_338381</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I NDUFA13 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6P6"/>
    <dbReference type="OrthoDB" id="3308at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009346">
        <property type="entry name" value="GRIM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06212">
        <property type="entry name" value="GRIM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="119" mass="13973" checksum="A165D54581148616" modified="2020-06-17" version="1">MPQDMPPAGGYEPVQYKRNLPARGFRPSYYFLGVTLLCTWGFYEFGKGVREHNELAREKMWSRIHLIPMLQAEEDRDQVRRHLADKAREKELLGGEFKVYHSDRFVRPTFAATPKDVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R4</accession>
    <name>A0A6A6P6R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_195337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6R4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="9334" checksum="EBAD8E3D06E3E260" modified="2020-06-17" version="1">MMKGVKCLVDFFFFVLLLMDSCFVVALCFLFVARSAPRIVSPALNNSLAFSGKTQPRDETQVVLTPRAESNAPQSRTQRAHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6W3</accession>
    <name>A0A6A6P6W3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoporin NUP37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_377943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6W3"/>
    <dbReference type="OrthoDB" id="5323870at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="765"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="828" mass="85479" checksum="8C1C0091A4EED579" modified="2020-06-17" version="1">MLDPLEPCVSRHGRALQISYDLPYRVHAARLYPLKSPNGSSVIVYGHTNGLGIMWRGGRARRRPQQRAPPAAKAPPKVNGTGSGSGASSADTIMIDDSDDDNSAPLSASSSKRRDPATWATTYDDAAFETEEDEYDAEKPYAPIVEQIDVPLGTAVLHLSIPPVPVDAMPSLRPANWTPSILNQRIVVAVACSDCSVRVVSVPLWPPPADAKAKGMLGEEVVTIGGMQSQDLPTGVALTWTARQPLVSSSWDEDSVYDENSDDAPTILASTEEPEVPRQWDLLVASVNTDLTGLLTISRLPLINQQNNHQTLSTESMLPFRSLVLPSPPISIAFSPSVCPSRRHTHLVVPDSAGSVRVYDPLLPGRGQSGPGTRPQSRRTEDGTASAYSGSRDLDSGSGAWVAAFRTPFDAGSGADVARLNMVAPATARRRRILDAVWVGHGSAIMVLMADGGWGIWDVVLKDPKALDPSHASRRSVTKALKPSSPATGFAAEGYLPGTATPSSTDERAGATELEARSRGSGGASRKDKTAFSLAPMTPNTRRSKETSALFAPTAPSAASPGTSFSGSTHTAVFAPPTGGLAVLATPPVVGPAAAAAAAAGNASFGSPAGSFNFGAFGGTGAGSSSTRARVASPQKPDEAVTVWLSGPDRAWRVAHLGALRAKLSTSTTTGSGAKGGAAPTSGSAVASAAAGFSRLDAVPPTLRGENCKWVEQLPPADATARALGVRGDVLVLGESRVGILGGVGSGFGAGMGFGGAGEEGGSGLFGRRGLEAREREREREREREKQGDMGLLARGELGLEGVGRLVDGLAGGSGGGSGGGRRVGFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P710</accession>
    <name>A0A6A6P710_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_268931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P710"/>
    <dbReference type="OrthoDB" id="3886346at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="275" mass="30014" checksum="3AE89309FD350E54" modified="2020-06-17" version="1" fragment="single">MSDGTNCFNYLVDNIPAWLASLEDVRRKMEEKQKEIALIPAPVQKQKQKTGSMDPPDECATPPYGHYHHFANRKRKTPSVLSGRLSGPSKYRTRSMIIVYYDSEVEKAFETLVRNIGTGRNLLRKGRMAARVEALTKAAPPSDGEDSNSDGDGDDDGDIDDIMAKLHYRPTRMMFTSTRAGRGINVRGVSNGRSPLPGSRGRDGGAAAADPAATFDQKFDAADAALESAQSFCERAAHQFLRDGDCRDEIDKAAAKFGDALALSRREVSAAEAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P738</accession>
    <name>A0A6A6P738_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_369739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P738"/>
    <dbReference type="OrthoDB" id="5977743at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF4">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="686"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="610"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="715" mass="78412" checksum="B800F8139676F335" modified="2020-06-17" version="1">MNLRYGGLRSTRDHFHAPPSLTERAASLLHAILSLSPALHQHGNRMPQRTPRRCGWWKKVHGLEVLITIVWVVVLYWGERKVFQESFDSCRWEDWEKWPQGATPHHLVFVADPQIVDPHTYPGRPWPLSSLTEAYTDQYLRRAYTNIQTELRPSTIMFLGDLFDGGREWGTGAYKSPEKRYQKYGHTFWLQEFERFGRIFFGRAAGAPPGQRIVATLPGNHDLGFATGVQLPVRERFETFFGEGNRVDVVGNHTFVSVDTVSLSAKGRESADERVWRPAMDFLDGVSDRMDRAVERELRRQSGRPLADKWRWPASVMDSAEVPAGVRPPPLVRPEDHNERFPTILLTHVPLYRDRGTPCGPLRERSPPSPPAPGQTAPPAVDPPNALSIAAGYQYQNVLFPDITQTIADKIGPSLQRAFSGDDHDYCDVVHRDLAPPPTTGDGDASTGSGSARGSVREITVKSLSWAMGVRHPGFLLASLWNPVDTRGRPLGSSAGAAAAAESDTVQTRLCLLPDQLAIFIRYALLAGATVVLLALRALVRALRRGRLLAPEGTPRAKNGVEGDGYEDEEDEEDEDDGMGRDAAPPTSASANGSSTPSEAAKSTTRRRAASLTAAMAMAESGGGGSGGGSAEGASSRDGSTPLYGVPLITHAGYFGPPRGGGGSGAEREKWGLGGKRTRRRRRTGWEVWAGEFGWAVVRVGGLVGTWYVWLVRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7X0</accession>
    <name>A0A6A6P7X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_281410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7X0"/>
    <dbReference type="OrthoDB" id="5283561at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="55597" checksum="9FB64C2D43FDB1A1" modified="2020-06-17" version="1">MHINEFPYEILSNILEEASRLEERDGVAYTFGLSQAPQPGYKAKLQRYVRGPLRPDMLRWDATASIRRVCPQWHQWAIEYAMREVYIRRWQGSERWAELPQQRDKYSLYELVDKPSGTAVYRDPYRSLRHTVKLLERYPELAAKVRRIWFDGFYVAETDVQICSALHACSSLQSVTMPWTTLRHLSGREWKALLGLGPTHTTPLRSLELLAVDLPARQAQDAANQYDERPLETGGVNFSQLRRLKIFGNTDFMPVCDRDLHAISRTATQLEHLHVTGLSTVTVDGVMALVKSSRATIRTLEHSPRADAGFRYPHPGHAQTTAGATAGATEEHLCEVLTSCPRLTDLSVSLPSMCAALFANRGVRWRGDCQVRAAHLCPVADHRPNNASADALAALADTLAEARGLVAAKAASVLPDTLNLELFYSDVIFEPHAARVHGDFALAEVSAGGRWPGRKGQSRKGPYGTTGLYGKDEGEMFEMVNEEVYLEGVRRGFVGITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Z3</accession>
    <name>A0A6A6P7Z3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Benzodiazepine receptor family protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_369898</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Z3"/>
    <dbReference type="OrthoDB" id="8841220at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033013">
        <property type="term" value="P:tetrapyrrole metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.100:FF:000001">
        <property type="entry name" value="translocator protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005859">
        <property type="entry name" value="PBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="20338" checksum="156124594ED3B96C" modified="2020-06-17" version="1">MTTHISSITLPAFVFEKPAVSLLLPVVLGNAVGLATRLDPNSKAYKSLKQPPLNPPPYVFGPVWTALYLSMGYASYRAWNAGMSSLDMEKVKLAKDSATLYTIQLGMNLVWMPLFFALRRPIEATVDIVALTGAATSLACVYGRIDTVAGWMLAPYVAWLGFASYLSAGCGYLNNWNFTQDITKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8C3</accession>
    <name>A0A6A6P8C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RmlD-like substrate binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8C3"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="299" mass="33698" checksum="210150E8F924B323" modified="2020-06-17" version="1">MSPGPICKEQPVYLIWGGDGWIAGLLRELLFEQGKAVFTTTVRMENRQAVVAELDRIKPTHVFNCAGCTGRPNVDWCEDNKEATIRSNAIGALNLTDCCYLAGVHITVFATGCIYQYSEEHKVGGSPFLETDKANFDGSFYSFTKSRVEELMKPYDNCLILRVRMPVSDDLHPRSFVTKIIGYDRVVDVLNSQSILQDLLPASILLAENKETGVYNFTNPGAISHNEILTMFKNIVRPDFQWKNFRIEEQSMILKAGRSNCELDAGKLVAKMKEFGHEIPEVHEAYEKCFKRMVANGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8N2</accession>
    <name>A0A6A6P8N2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_419098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8N2"/>
    <dbReference type="OrthoDB" id="437457at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="40788" checksum="3AA20B6B831AA19F" modified="2020-06-17" version="1">MKDFVRPPVITNDKIKGYTRAILLRPDEEEPEFVWLPYEEPYPGLQRPKVTDVLGEEADRKAIGPTIGDPVLRRLMHHGLWIIGNGMRMSGFLATKGNKALRNIVGLEATAWLPVFHGSVLIFGSKQLSGEPKTLDDLDTGDLRPAVNYLSWYQNAAKPLRLARELTYPVQGVRIVGNGITWEEALESNMIVEVTVSPMENMFWRTPPTTVSLRLGLPILMTKSPKYQWTTKPENPGFNRHVPALQVCCDPSYAFRTSKGTLTGFGRMSEWWLHDAKEVILAREDRKPLHVYHVMALIDFFGTLLPFFRQYSAAPDDRKQGCMEDILAKISKESFLAFFNDWKKANRFSSEIPSMYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8W1</accession>
    <name>A0A6A6P8W1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_361291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8W1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="29891" checksum="1B5B07E99E11C3CC" modified="2020-06-17" version="1">MAIPPSVVLPGGPPAKHQATRAAGLGRNLWALAEPTEAGGAGGVLLQSKALAACTEAARKTSGPSSAPSSRLACSPLAPPARRYGRPPGRDTPPLYSSRAGRGFWRREARRSSPKRGLRASAKQNTSAADVIGRCPFVASCSSLCAPPPPPSRRRRPSRIAFRGRPGRHVVRPTPTNPSAKSSAAQAERERMGESSTADETARAPRTPPWTPDRLAAFLQCLAGAGGSFSWPSRKITHEQGAPFCEATASGTRNDARNASLARAANREVPPPRETKKDIPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8X2</accession>
    <name>A0A6A6P8X2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_161891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8X2"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="201"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="303"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="407"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="521"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="588" mass="61203" checksum="F5F32A0AF84C4A7B" modified="2020-06-17" version="1">MDGGPNISEILAALAGQPNAGGTPSQSATPQQQQPAAAAYGAPAAGAPAPAGYPGALTTPTPPAGAGFALPQPTSTGHVDLRNIRAVNSGSVSYSDALAKARGFAAERGVSTYDGRSGAGSPRDDPRGSSGRASYRRSRSRSRSPPRRDHYNPYRDDRRGGGGYRDRSRSPSRRGNFSPAPGGGRGRDGFRSPIGNNGREEDNQETILVDSALVGLVIGRQGENLRRVEQDTGTRIQFITGPDSGSAQRQCRITGNARSRLDAKREIYRIIDENGGNPPRETGPGGRDMPGSVKPNQPLLREGENSIQIMVPDRTVGLIIGRAGETIKDLQERSGCHVNIVGQNKSVNGLRPVNLIGSPAAAAKAKELILEIVDSDTRNMGPPPRESRGGGGGGGGSGYENHGGSDGKLNDHVTVPSEAVGMIIGKGGETIKEMQNSTGCKINVAQASGADIDREIGLVGSKAAIEAARQAILEKVETVVSRDSKNGGFGGRRGGRDNNSASDPYSQQQQAAYGLYQQPGQNQYAAQQAAPGTGTAGAGDAADPSMDPNNDPRYAPWGGYQNYVAMWYAAMARQGQQAGGEQPKPPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Y7</accession>
    <name>A0A6A6P8Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_181232</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Y7"/>
    <dbReference type="OrthoDB" id="67388at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2210:FF:000002">
        <property type="entry name" value="ATP synthase subunit 4 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0138">CF(0)</keyword>
    <keyword evidence="4 10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="265" mass="28634" checksum="64563E01A8227248" modified="2020-06-17" version="1">MASRLARTAAGKMWLPVCFPRAIGRKPDVLVGAGRLRPTVSAARSLRAITAPITQSRAASNVPAEDPKKKAQSIIDSLPGNSLVSKAAILSTGAGLSIAAISNELYVLNEESIVALSLLTVFWAVAHYGGPMYKEWAQGQEAKMKGILNAARDDHTSAVKKRITDVKDLSGVIDITKTLFEVSKETAKIEAEAYELEQKTALAAEAKSVLDSWVRYEGQVKARQQKELAETVIGKIEKELENPKVLKQILDQSVADVERIVSAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P956</accession>
    <name>A0A6A6P956_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P956"/>
    <dbReference type="OrthoDB" id="4207369at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="972"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="802"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1190"/>
            <end position="1201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1201" mass="126618" checksum="198B7DBF83B5AC4B" modified="2020-06-17" version="1">MAPSPRKGAAAGRPTDTAAAALHWSPGDATAFAPSILARPKVHRAWERQPKSPFARKSRYRKVWRRYDLRSTSRNRHATEETAGGLSAHLADHVDECDETIANASPSKRIVKKLRTGASAAMAKSTRIKGHAGFEGTRWDRRKSGLPRKLPIQQVQDPFAHPTEEVDEQPQPTLATSPRMDESTSDITTMPLGDAQDLATAVLAEGAGVFPPRSLAALDDDDPFKSTNIEEAFVDSTDNVDDAKLQSYALGGAALIDSSGDCSPIEASAAETESSEAAIGLDNTHANMGAEVSKVQRSPTISVKVDAWVRPSVDTPSRTSTPKSPSLSPRDLSPVSLAGLFSPPSKIGSPQKPAAKSPEAILDTVQITPLKKPPEAILDAIQTTPSKSPSAQADNIQESPASAESTQVVPLQEAELGNCLQEQRQHQSSIPVAGKLTKEQADTEKDDKVQETKDATKEFSSTIDANAVLEAAPTLEAVSEELAPQASTNLVSEDKEDTAHLDSAATESSNYVPKEGGESPLIDFGDTVTDAIIVTETGHPGAAEDATGRVIADETTQQNQETPLRALDAELSKDGVIDARVGDSGESAREEEGDASEDAAGRQPEGSEIGDVADVNEEGQKSAEVDNAACSPETPAAVEDDIAASLTLPIASQPPQLPAREETSTHLEADTAILKDFLSRAAASKANKSETIARRASFSHRRDSDAIRQALASPPKGGDNKDPASPSNDKVAGVPASREDLPLAKLLEAAAEDDTTGDITATLLLQPSVGASSETTVAELDDQQQQPAAHFPQQHDQEQSHQQKPSSSSERQPTRRSSRSRTPRIPGAPPSSSSSTPRNISIRSRHDGADLVLKKKEADELSSLTRMNTRRNKGASVPAGVRLSKLAVERMNSVDSDGDGDAAATAAAAAAAVVNSAGNRGSKSGGANKVVAVAAAAAAATTEGAKSVRWDRRLVYFHDGKMKAAPLAPGLAARQRNEDGTLPSALTPVKPSSESHKAGSEAGDTETYLDGGEAPAPVESSKRSSGKHHSSRMRRLKGLGAANGTPAKGLSNNAPLLPADVEKAEDREKDREKDRDREDRKHRHHHHYHYEYYEHSSKHHSSSSSKKRQLPTPRKLKFNPAPVAVGGGTMAGGHGGPAAAGHAGSAGPNFVPEGKENGHRLASPKKVKLSGGPTPASSGLASNMAPAGRTRSERLVRLRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9A0</accession>
    <name>A0A6A6P9A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative plasma membrane phosphate transporter Pho87</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_163351</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9A0"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="628"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="671"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="696"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="763"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="811"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="857"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="881" mass="96931" checksum="EBEC1BF51C213E0A" modified="2020-06-17" version="1">MKFSHSLQFNAVPDWSSHYIAYSNLKKLIYSLEKQIHQSKPHHPPSTNTGDAESSPLLGSDQGDNPDPDVIFTNALDHELEKICSFYQIKELEIYGDVDQLLQDESDFEADQGGLEVDGAGQGLTSSKLLSRAQKERSGSIFRSFTFGGGSGWKGRRRTSTISRSQDGADTIEEDADEDSDDDADERTGLKRKKSSTGARSTGQRGWDSEDLRTSTDFPTTLSRRRTSMADDDLRDMQLSALFDSGMTLKKRAVSMYVSICELRSFIQLNRTGFSKVLKKYDKILDRKLKDSYISRFVEPAYPFQKSTMDHLAENLTKVEQAYANLCTNGSVPEARRELRLHLREHVVWERNTVWREMIGIERKAQAANMGLRQTMLGQETDPSKARLQGDEDQPETKEIATPLGRYTCPGWLLSGTFYTLVGIVAVFFVLLFAPIMKSEVEQKCLALVVLVSLLWATEAIPLFVTSLIVPFLVVVLQVVRSPDPPHRPLGAKDAANFIFSAMWTPVIMLLLGGFTIAAALSKYNIAKMMATFVLSKAGTRPRTVLLTSMFVATFASMWISNVAAPVLCFSIIQPILRNLPSDSTMSKALLLGIALSSNIGGAASPIASPQNLIALQNMTPQPGWGAWFFIALPVCIISILLIWILLLLTFQPGKNTTIVPIRRMKDKFTGLQWFISAVTLVTIVLWCVTHQLEPVFGDMGVVAIIPLVLFFGTGILTKEDFNNFLWTIIILAAGGLALGKAVNSSGLLHTIAQSITAKVQGFSLYGVLIVFAALILVVATFISHTVAALIVLPLVKEVGQGMTEPHPNLLVMGSVLMCSAAMGLPTSGFPNMTAIMMEDSQTGQRYLQVKHFITRGIPSSIITFLVIITVGYGLMIAVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9E1</accession>
    <name>A0A6A6P9E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial large ribosomal subunit protein L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_335579</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9E1"/>
    <dbReference type="OrthoDB" id="268521at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000003">
        <property type="entry name" value="54S ribosomal protein L16, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="236" mass="26233" checksum="A63EA29D0250FDF8" modified="2020-06-17" version="1">MVCHPFHAKDAQWRFAMLQPLTPISVTRRPGCQSSPRSSISAPRLFSTTSPTRNWLVPPSGETKKSPKGRPRMRTGGSVKGTTVVWGQYGLRMVDKDRRLSAHHLRLGAETIKNKLRGMKYRLYHRVAAQIGVYTKGHEMRMGKGKGSFDYWAARVGVSKVIFELSGQVHEKVVRDAFRVAGNKMPGKYEFVKYGDPPVMGVTKLGNGVTAESLLRPRRQAPTNADRVPPNGPPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9E6</accession>
    <name>A0A6A6P9E6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 8">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_280550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 8"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9E6"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071244">
        <property type="term" value="P:cellular response to carbon dioxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="23411" checksum="479C5FCBA25FD76E" modified="2020-06-17" version="1">MPADLFELEELRQLIEGNKTFVRKTLVNEPKLLKKNAAGQSPEVLWIGCADSRVPETTVCHSKPGDIFVHRNIANVVQADDASSAAVIEFAVAHLKVKRIVVCGHTKCGGANAALGDADLGPTLNRWLEPLRALRRKHEGELKKLASPDDCATRVAEINVHAGVETLKKNKTVAKAMEDRGLTVHGMIFDIAEGELRVLEEKPAAQGLWNMVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA01</accession>
    <name>A0A6A6PA01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vesicle transport v-snare protein VTI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_335949</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA01"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.400:FF:000002">
        <property type="entry name" value="Vesicle transport v-SNARE protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="25429" checksum="49FA5497F84E240D" modified="2020-06-17" version="1">MSNILDSEAGSELFGSYEAELKLVQADLNQKLDQIPELAGEARKAAIHQAERALEEANELLDQMRIEKQNIPAGAKSKVNQRFRNFETDVDTCKRKLKSLSDDRKALFGSRYTDDPGVDEQLEQRQQLLSGTQRLERSSGRLRESQRIANETEEIGRNTLADLEMQRETIQHTRSGILESEGYTDRSIKTLRGMARRMATNKVITIAIIVVLVVLIVAVVVSKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA68</accession>
    <name>A0A6A6PA68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_418783</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA68"/>
    <dbReference type="OrthoDB" id="3214149at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000201">
        <property type="entry name" value="C2H2 finger domain protein (Gli3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000031">
        <property type="entry name" value="GLI family zinc finger 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="201"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="431" mass="47800" checksum="F4FAD638447D823B" modified="2020-06-17" version="1">MDSPGSPLSDLSSDEFLQEKTEDHQSVASAEYHDSPQSRPSKRQRTGGGGANPVDMRHGVADRRASAFGSGALGNMIYPPTGDETDVSEDTEGSMPASPTHHGAGGARGAGGGAAKADAGGEGDEDSFGHEQVTVCKWEGCEAGDVGNMDKLVEHLHYEHIGTRQKKYSCEWVDCSRKGIPHASGYALRAHMRSHTREKPFYCTLPECDRAFTRSDALAKHMRTVHETEALRPSDPVPKHHSANPSNKLQRIRLVFNKNSAAGDAAGDKSSMPVSPSQPSGPVESEYDHNNVTYVADGTGYKLKFPSDIHFTDEEARLSPDQLFQLLRRQLHWAQQDGEDLKAEIEELEKRRKEEWFAKELLLENVLEAEEAAIIRREEDREREDLKAALERDVEPSKKLKIKGDERLWWRHAREGVENDGDRMEGVVRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAX2</accession>
    <name>A0A6A6PAX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_334312</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasmic vesicle</location>
            <location evidence="10">COPI-coated vesicle membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAX2"/>
    <dbReference type="OrthoDB" id="10261439at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000260">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005727">
        <property type="entry name" value="Coatomer_beta_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="11">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="12">
        <location>
            <begin position="679"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="13">
        <location>
            <begin position="820"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2461095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="956" mass="106824" checksum="161566B5E58D3EE5" modified="2020-06-17" version="1">MASFLDTAYSLVHQDNSADQPTLQELKTQLERGTDDTKVDTMKRILTIMLNGEPMPGLLMHIIRFVMPSKSKPLKKLLYLYYEICPKHEADGRLKQEMILVCNGIRLDLMHANEYIRGMTLRFLCKLREAELVEPLLAPARQCLEHRHAYVRKNAVFAIASIYSHLESLIPDAPDLIQNFLDEENDSTCKRNAFAALASISHEKALEYLSAVFDGIPNADELLQLAELEFIRRDAVTNVQNKSRYLRLIFDLLEASAPTVVYEAASSLTALTTNPVAVKAAASKFIELSIKEPDNNVKLIVLEKVDQLRQKNEGVLDDLTMEILRVLSSPDIDVRKKALEIAMEMVSSKNVEEVVMLLKKELSKTVDEQYEKNNEYRSLLIHSIHQCAIKFSEIASSVVGSLMDFIADFNNASAVDVISFVKEVVEKFPDLRHSIIERLVSTLSEVRAGKVYRGALWIVGEYSFEEKDIREAWKRIRASLGEIPILASEQRLLEEVPDGQPDPKDQINGHAKVAPTGSRKVLADGTYATESALTSQAAVKAKLEAVKAAQKPPLRQLILDGDYYLATVLSSTLTKLVMRHSEISKDAARTNALRAEAMLIMISIIRVGQSHFVKMPIDEDAVDRIMSCVRSLAEFAERKELETVFLDDTRKAFRTMVQIEEKKRAAKEAIEKAKTAVQVDDVVQIRQLAKKNATEGADEIELDLEKATGGDMSSEDLASKLSRVVQLTGFSDPVYAEAYVKVHQFDIVLDVLLVNQTTETLQNLSVEFATLGDLKVVERPTTQNLGPHDFQNVQATVKVSSTDTGVIFGNVVYDGSHSTENNVVILNDVHIDIMDYIQPAHCSETQFRTMWTEFEWENKVNINSKARSLRDFLKQLMACTNMSCLTPEASMKGDCQFLSANLYARSVFGEDALANLSIEKEGENGPITGFVRIRSRSQGLALSLGSLKGLNKVGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBN4</accession>
    <name>A0A6A6PBN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic porin/Tom40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_84771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBN4"/>
    <dbReference type="OrthoDB" id="7827681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00558">
        <property type="entry name" value="EUKARYOTIC_PORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="285" mass="29943" checksum="5E7A4C9DF0BFE28C" modified="2020-06-17" version="1">MPVPAFSDIAKPSNDLINKDFYHATAAALEVKLKADNAVSFTAKGTSAHEGATNASLEIKKGLNIKGATLTGAWNTANMTSEKIELDNVIADGLKVELLNAFSPAAGNKGQKANLYFKQAAFNGRLFADYTPTGAFSATVDGVFGHEGFLVGGEAGYDVQKAAITKYSAAVGYQTPQYSAAVQATNSLSIFTASYYQMVNAQVEAGAKAAWDAKTSGPVGIELGGKYKIDPESFAKGKINDRGIVSLAYNTKVKQGFTFGIGASFDSQKLNEAGHKIGTTFTFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC02</accession>
    <name>A0A6A6PC02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_360428</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC02"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="422"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="523"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="636"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="750"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="532"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="642"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="774" mass="84032" checksum="9248FD92A98C6223" modified="2020-06-17" version="1">MAGATITSAASGTEIGDKASLKRSRRLVQQKARPNLIRQSNGDDDGVNDSDAASLYSAASSNADSASSSDESYQTDDDDRRPSTQPTPLTVSSPSNPHASGANTPKRPQRPTYYCPHPGCTKTYTRPCRLSDHLRSHSNSRPYVCEEGSCGKAFLRRAHLKRHVAESHDEGRRVHVCGWVSDEGAERGDNAKGEKQKSCTASFVTAAKLKRHREAHEERLKLRCTEPRISADGEEDGRAGTCGAKFRKKATLQRHILTMHRGKEKLFVCEEQDWGGAGSHGKKCGKRYLTDSKLREHVNRVHKWRKFKCDICASEALMGGTATTAAKGNSVSQTSGATTTTVPSSNQGEHPIAFPTAALLQAHIKTAHPPRCNICSRTFASQRALRDHVDLVHPTATRISDPTSGSSAEQLRDQLLDARRTHHCTYPDCGRAFTKPFNLKQHIRTVHEGRKPFLCGPEGAKGLLAAREEEVRAWAKDVAGEGEGAEGGGNEAHVACGRSFSTKGALQEHVRVLHLDLLGMVQEHRRKKRKAKTEPRGRDDQPAKRGKGADGEPLSTLTGEGYELERGRRIACLLAPKCDFRFHRAYDLRLHVNAVHGTDMDEGQVAEALAERRALGGGPFWIGDGVGDLLDLGDEDEDGDDGGWGGVDGGEEPGWGVLGDERHQDDEDEEFGLLFGARDDALARGAARSAGPDWAYAMAGQEKNEGFMDFMAGMSANRWGTLKAHVELFTVFTSSPAVALLAAKLPLRNPATPSAHHSAKTARQRGGESGNGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC07</accession>
    <name>A0A6A6PC07_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin-conjugating enzyme E2 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin-conjugating enzyme E2-18 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_278616</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC07"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019789">
        <property type="term" value="F:SUMO transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="17">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="15">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2461484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="18055" checksum="874ACA2F27EBAF6B" modified="2020-06-17" version="1">MSLCQNRLQEERKQWRRDHPFGFFAKPVRTPQGGLDLKKWECGVPGKDKTLWEGGLFKLEVSFPEEYPTKPPKCKFIPPLFHPNVYPSGTVCLSILNEEEGWKPAITIKDILLGIQSLLDEPNPDSPAQADAYNLFKKDRYAYEKKIKNIVRENPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC70</accession>
    <name>A0A6A6PC70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Calcium-binding mitochondrial carrier protein Aralar2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_278523</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC70"/>
    <dbReference type="OrthoDB" id="10266426at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF1">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06780)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="217"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="151"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="261"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="399" mass="43488" checksum="E21D461E5FA7B5B3" modified="2020-06-17" version="1">MSIKGDQAPSDSAQKTVTRAHDGHPPHPSPLGTPLASAAAFCAQLPSSSVNSFCGAMAGVASGVVTCPLDVIKTKLQGQNAFRSASGKLQSGSGTIYNGMVGTARVIWRQDGVRGMYRGLGPMLLGYLPTWAVYMSVYESSRESYYQKIENKWVARISASITAGACSTLVTNPIWVIKTRLMSQTSSRATDEIRTPWQYKSTLDAARKMYRTEGLGAFYSGLAPALLGLTHVAIQFPLYEYFKMQFTGLQMGESSSEDENMHWAGIAAATFLSKVCATSATYPHEVLRTRLQTQQNTLPHHSPEEIAFRGALGHGGSTRARGSSSSDGMINIPRYRGIVQTCRIILKEEGWRAFYNGMGTNMIRAVPAAMTTMLTFETLKSTITRVQHEGQKVLEEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC87</accession>
    <name>A0A6A6PC87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_376451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC87"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="20497" checksum="33BB8694840417D0" modified="2020-06-17" version="1" fragment="single">MVSQYRRQNSFGPRNYNAVRLQWTKNERDFSDNQAQETTDSDSVSDTGTSELDDENLSRDAGSSASPDVDDSDQGSHFEDGLAASNQPLGCDISLRPVRGSNELSPAAQTSPTSPPSSDGYESSLSGTESSSFSDSAYSSETSPSRSGLPHLGSKILCAPSIVLRKRARIDDDLDSDTGYSADIEDNVKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCB7</accession>
    <name>A0A6A6PCB7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SUZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_89399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCB7"/>
    <dbReference type="OrthoDB" id="278430at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUZ" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="575"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="726" mass="73353" checksum="993B7807547DE844" modified="2020-06-17" version="1">MRRGGDGATPSGSNTAANSENPSKATSEVGGESGSDGGGGGQAAANSTEPKPAAGPITREEKEARYREARQRIFGTAEASESPKDGENTNANNNASEAKDVSRSSSTTGRKKNGPNSGAKKRNYNDDGFEARSQFNSFYPPGAMGPYAVQATYQSQTPDGVWYGGQYPGVAMSGVPPPHFPNMQYGNSMAPPMIGQDPSQQDYSQWQGQPYVEANGGYGGGQGFPGPANGYSTPNSYNPSAFQRGIPPQFQGPPANSSPRGAQAMAMKSSGTPGPAANQAQGHGSHQQHHTSGGEGAHQPWGQMPQYMGAGGPYPMDASGQQPQPWMHQTGGQQQPGGGQQPPNSFMPHQSAPPYLPPYGHQMPPHSHSTTPFAPNHKFRGPPTNPHHPLPGSYNRPQFNPQSQAFVPGGGPRSVSQPPHQPSSSPLAQPTMTAAASPYGLPAKPHVSSAPPLSNGAQQQRHQGMNGFAASGHRTPRMSPPHASYPVVSGGGAPGAVGPQPFATTGPARLLQPQQPQTMQQAQQHRKQSPLTHPLPAGPVVATSTASAPGGRGPTSGGGAGGNGRNASGGGTNSGRGTPLQKGGAALQQGQGPEQGLTPVVASSTAATPSSTSANSAASGTSNNNNPTAAPQQQQHHSSIAKWGTPSNLPPKPPPPVNSQLPPKFLPGMYPGGAKGPPGSFASAANAAAVAAAAAAVGGGAVPGVNSGNGGSSAGYGGQGVVGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCR4</accession>
    <name>A0A6A6PCR4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_261443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCR4"/>
    <dbReference type="OrthoDB" id="5337378at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="193" mass="21564" checksum="7E425660C91A46AB" modified="2020-06-17" version="1" fragment="single">IDDRYVFRKELGSGCEGTASIYTDQTTGEEVVVKTFFGTGRNAVPDAVGEVFAWRQSMWPAEIPALLLLSGFGGKNWTAKVHESGSHGSGYVPILDYFLVTRNERNESVAPQWHLVMPLVQRGTLQSLAGRVRAENPQPPHELDLSLRPTLRRLLRTLADLHARGYCHDDVKLDNVFALSRTHWLLGDLGNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD46</accession>
    <name>A0A6A6PD46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_295145</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD46"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="10">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="894"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="427"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="900"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="927" mass="103489" checksum="11E36251C8C43198" modified="2020-06-17" version="1">MSNYQFTDRATQALSEAQALATQYAHSQLLPVHLAVALLDPQPDLSKDQQAPQHESHAQASAPLFKQVVERAHGDVQQLSRNLNKALVRLPSQDPPPDHVSVSPAFSKMLRSANDLSKTQKDSYIAVDHLIQAMVQDSTVQRALAEANVPKTKLIDEAITQIRGTRRVDSKTADAEDAGENLKKFTIDMTAMAREGKIDPVIGREEEIRRVIRILSRRTKNNPVLIGEPGVGKTTVVEGLARRIVDADVPANLAACKLLSLDVGSLVAGSKYRGEFEERMKGVLKEIEESKEMIVLFVDEIHLLMGAGASGEGGMDAANLLKPMLARGQLHCIGATTLGEYRKYIEKDQAFERRFQQVLIKEPTIPETISILRGLKEKYEVHHGVTILDGAIVAAANLAARYLTSRRLPDSAVDLVDEAAAAVRVTRESQPEALDNMERRLRQLQIEIHALEREKDEASRARLRDAKAEAANVEEELKPLREKYEKEKERSREIQEAKMKLDSLKVKAAEAERMRDIQTASDLKYYAIPDVEHRITELEAQKARADAEMYSRANGQQEALLTDAVGPDQINEIVARWTGIPVTRLKTTEKDRLLHMEKHLGHIVVGQKEAVTSVSNAIRLQRSGLANPSQPPSFLFCGPSGTGKTLLTKALAEFLFDDPKSMIRFDMSEYQERHSLSRMIGAPPGYVGHDAGGQLTEALRRRPFSILLFDEVEKAAKEVLTVLLQLMDDGRITDGQGRIVDAKNCIVVMTSNLGAEYLSRPNAPDGKIDPTTKEMVMGALRSYFLPEFLNRISSIVIFNRLTRREIRKIVDLRIDEIQKRLQQNGRNVRIEMTDEVRDYLGSAGYSPAYGARPLARLIEKEVLNRMAVLILRGTIRDGESARVVLEDGHINVLPNHTDSDMDEDSEMYDEEDAIEELEDGADMDLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDA9</accession>
    <name>A0A6A6PDA9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL22</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_367987</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDA9"/>
    <dbReference type="OrthoDB" id="10254664at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000010">
        <property type="entry name" value="60S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="22086" checksum="A2B4E9C8AB8EC7AF" modified="2020-06-17" version="1">MEAARALPGMLVRYAATYIEPAKSARARGSYLRVSFKNTRETAQAINGWKVDRALQYLENVKNKAEAVPMRRFAGSVGRTAQGKQFGVSKARWPVKSADHLLGLLRNAEANADSKGLDTGNLIIKHIQVNQAPKQRRRTYRAHGRINPYMSNPCHIEMILTEGEEVVQKGPQVVRREEARLNARQRASRVRRAITAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDL2</accession>
    <name>A0A6A6PDL2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HSP20-like chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_329831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDL2"/>
    <dbReference type="OrthoDB" id="5511210at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="31"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16010" checksum="D026D574973FB244" modified="2020-06-17" version="1">MMGGPNGLAEFLQNNVFGAGAAGPESGAKEGAAADFTPEADVFDTPAAFVVHISLPGAAKEDVDVSWDAEKSELRVAGVVYRPGDEELLKTLAMDERKVGPFEKKVRLGSRANPANVDVEGITAKLENGVLRVDVPKLDGEYVEVRKVDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDN9</accession>
    <name>A0A6A6PDN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bola protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_383051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDN9"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="90" mass="9666" checksum="6416BA85BBE8104D" modified="2020-06-17" version="1">MAESSGITAEGIGAALKEKVGATHVEVEDLSGGCGQMFQAVIVSPQFDKKTTLARHRLVNGALKDEIAAIHAWTPKCYTPEQWENQRKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDS2</accession>
    <name>A0A6A6PDS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flavin-containing amine oxidasedehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_330490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDS2"/>
    <dbReference type="OrthoDB" id="2019015at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF20">
        <property type="entry name" value="FLAVIN-CONTAINING AMINE OXIDASEDEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="549" mass="62530" checksum="D084631EB23FDEE3" modified="2020-06-17" version="1">MAPHGQNVDKRKNIVIVGAGAAGMSCAATLANHPDNFKVTVIERMPYCGGQATSISLDKKKYGTSWMNDGVQGGSPAFKHTGHFMEKYGHLWQEVRLQVGFGKGEDNFWTNVFPTHLVEKHQKDIRKFGKVLKLIKYLMPVLGLVPIKYMLKLFLFNKDFGDKMVIPLIALFLGTGNQTPNVACAILERLFDDPNMRLWNYDEGMLLPNLPEMVTFPKLRDFYQDWQGDLESKGVKFRLNTDVTKIISRDSKGVVLQTRPFDATLNEQGRKFAPQVIHDPRGGWTGPPSDPESYDELVMCVLADAALKILGGTASLRERFVLGGAAFFDDITITHSDNVYFDKIYEPHFEASLAAQPRSKAEEEHLAFAKGEVATNASGEPSGYRPMYFTHSYNEAGEPQKIEMSFDVTNYQHQFRMDHGADVPPIPYERHVFQSIFLDKRNADLWTMPEIDPSKVIESKWWHQLGHRWQHYLRVVPGMMWLNGKRRTWFAGSWTLVNMHEIACVSGIAAAYRLGADYEVFDDYAEDLFKKYLLLSHGVRYKRGKRKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEA3</accession>
    <name>A0A6A6PEA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEA3"/>
    <dbReference type="OrthoDB" id="5416609at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="42"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="616" mass="69777" checksum="3761D0289E973C97" modified="2020-06-17" version="1">MEYYRYERLESGSIRLLNVLNTQTAEIRCQLLTADLNTAPKFIALSYCWGAPKGNISVICDNAIIHVTPNLHGFLTHFASQGPEYLPPVWVDAVCINQEDINERNAQVAMIQHIYQQAAKTVVWLGEGTEESDIAMKFIPQLLRADEKSKEDRWTSQDLKEGDVRKLCLPSRTESLHFFYSALFLRPWFRRVWIIQEVAMSQDVEVVCGQQRVSWKDFSRAFWFAHQLGVQVSSDIDKGHIEGLQSTFAIIKTKESRQCGLRVDLLGLLLRCRKFLASDVRDKVFALLGLADDTGPEALDFQPDYGLDIATVYTRLAFALIHSESSLDVLSARMAPSRELQVMLPSWVPDWSTPVGLPTFSGRESLANHESFDMERDRNATKDSLAVARLGENEKTLGIEGYVVDHIERLGSVLPGSDELQDYKIYLFAVLSLMRSYIQVFIEWEGFAEPFSGETYAWTNESIMDAYWKTITACSTHMEAEVSRADFLEWNSYYHPLLSLRNLVGYSIASSSLFAWLTLAISLLKILFRGSSDPIFGTALDIAENRRLIRTSKGLLGLAPAAARQNDRIGLFKGGRVPLVVRQKTQHWELIGDVYVHGMMEGELFTADSCETMWFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEX0</accession>
    <name>A0A6A6PEX0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_13133</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEX0"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1900:FF:000011">
        <property type="entry name" value="Spindle pole body component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="160"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="499"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="886" mass="99734" checksum="6F4A809C907C6C48" modified="2020-06-17" version="1">MAMSSYSNARPSPGTDQRRPAQGAAPRSRVPSSAPDSERAPRRPAGVSERRTDRTSTLSRETMAMRSRNPLAQSNESRVNSRKAKEANKASRPATPAASTKKTEEEKPKRWTPCASIIPHTTAPLASRVSVPPLAQDAPESLQPVALGKLSLKAQESVIVEDLMFVFMGFEGQYVRYARTYNPHEEKDKLVGPSFQILHGLDPSLRDLTTSMLKVASHYMALEAFVEVQSREEFGAVNHALCAAVRKLLKDYLILIGQLEHQMLTNATFTLHQLNLHLKTTSHMLFQLYNLGQELLKANSILEDDADDSLDDTDNFEDILESLKEGGNFAQGVPGKKMCKGGNVLGLITKRLASMSGDPAARTLLTTLLSESSRPYMTMLNEWLHHGGIKDPHAEFLIKEQKSIKRERLDQDYTDEYWEKRYTIRDNLVPPQLEGVKDKVLLAGKYLNVVRECGGVDVSKAVTDVPTSFDDPRFLENVNGAYVYANSTLLDLLLTKEKLPERLRSLKHYFFLDRSDFFSYFLELGDHELQKPVKNVNVSRLQSLLEIVLRQSGSVAAEFPYKEDVKIVMNEDGLTNWLMKIVNVTGLDQDAATGNITNYLTPAAQTSSVTNEKDISGFEALVFDYAVPFPLSLVVSRVTLTRYQLLFRYLLSLRHLEMSLTNSWKDHCKSLSWRHRSSNRKIEIWKRKAWTLRARMLVFVQQLLYYCTAEVIEPNWQGLMSRLSISDETRDVECPSTSDSKPVKRTVDELMQDHVDFLASCLKECMLTNSKLLRINSKILSTCTMFTKYTKSLSRYLAAADPDFATENGGTNAASQSTSTQYDPSKLDTIIDVLQKYEDNFTRHLKVLLDTLNYLAATETVVFLSLCARLSTASVGSQGQMDAMYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PGF8</accession>
    <name>A0A6A6PGF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GTPase-activating protein GYP7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GAP for YPT7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_277742</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PGF8"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000032">
        <property type="entry name" value="GTPase activating protein (Gyp7)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000005">
        <property type="entry name" value="TBC1 domain family member 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="451"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="756"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="756"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="768"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="799"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="823"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00072091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00082648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="841" mass="93823" checksum="EC37041C4AEA7940" modified="2020-06-17" version="1">MASPQSPPSPTASFYDMSDDEEGEYNTILHTSSGSGVKLLFSKSKVYVHPTPSARDNIPGFIALVEQKTPSPPADAPRPTSSSSNRSHRIPSSSLLLAWVPESSLTSAAYETYVKVDLSDSSSPPRQSYLVPALPTTTAHGPLASAAGAYAFAVPVSEIFSLLVRPPSIGWWFGSVVINTRAGDSFPALFFHDSECRSTILQRKRLARESFDPFGAGGSMFWGGDEVLRWLKRYVDVERSAAEPNIYLVEPSEADRASFGKKSPHAAGAGAAGPSSSSPSSPSHERGDSGRHDAAMDPVTKAFKEARWSLLEKLSQVTTFTRRTARAVADNPSLPPQVRRLLHNPEVQTLQDEFDSARLYLARWAAGVAEQAERERGRRIWTARDVLAMEDSAVGEFEILDVEGGVGAKEGEARRKPVGLPEWKGWFHEREGYLLVTPDEVKERIFHGGLDPDDGVRKEAWMFLLGVFDWDSSAEERQAVMNSRRDEYIRLKGRWWESMVEVDGDGDGEGGRSAEEKEWWKEQKNRIEKDVHRTDRHIPLFAGEDTPHPDPDSPFADAGTNVHLEQMKDMLLTYNEYNRELGYVQGMSDLLAPIYAVMQDDAMAFWGFVGFMERMERNFLRDQSGMRRQLLTLDHLVQLMDPKLYLHLQKADSTNFFFFFRMLLVWYKREFAWADVLRLWEALWTDYLSANFHIFVALAILERHRDVMIEHLRSFDEVLKYINELSGTIDLPSTLLTAEALFRRFQRTLDALDRRASFPPPRRAELEPAPPAPAPAPARGPTAGSGTGANGKAAAPRGEGGREGPGGKEEKEVSAELRALLSRKVERMGGAEVREHGGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKJ8</accession>
    <name>A0A6A6NKJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Altered inheritance of mitochondria protein 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Found in mitochondrial proteome protein 29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_176192</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIM9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001717">
        <property type="protein sequence ID" value="KAF2452260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKJ8"/>
    <dbReference type="OrthoDB" id="2831558at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051035">
        <property type="entry name" value="Mito_inheritance_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="8">
        <location>
            <begin position="96"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="548"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="64809" checksum="48F887D000D1BECB" modified="2020-06-17" version="1">MMLARLGRFRKSIRTNKTVYPGDFTAKGKRFLHGFDVAENRPTSIDPFSYTSGRWLKCDSLQRKARHINFDYRALCQKAVEACPGASEIVRHEKNEGAFNRVFILHMDDGQRVVARIPFRLAGPRRLATQSEVASMTYLRQYTNIPIPKVLDWNDDETNTTGTEYIIMEHASGVQLHGKWSSMSTHQHMLCVKSLATLVKEMMTLNFPAFGSIYFADAPIEPAIKIRLAEGFCIGPHCGAPVWPCSPVELSLYGEKMSRRGPWSDIESYCSGLIDAGYRRLPDAEPAVPRLDYQGTVQEHLRLIKASDEVIRKLITSSMLRNISTPLLLHPDLHKRNIYVSDGDPTQIVALIDWQATCIEPLFSYASEMPDLITSPMSIPISAGTEDVPALVENQEKTKVEKDVSICQQTFEVAMKAWAPRFHDARVTDETILRVLRYCSTSWRDSAAALRQELIELSQRWTALGLAGSCPYQPTAEEIQNHRKQYEDFESLQRLKLFLIRATNSNSGGWVPSDHWDAANEAHQLAYEEWMQTARDGDESEMTEEKAKKMWPFDPPRGSGMSSHAAMEAISSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKX8</accession>
    <name>A0A6A6NKX8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SecY subunit domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_175125</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKX8"/>
    <dbReference type="OrthoDB" id="420669at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000002">
        <property type="entry name" value="Transport Sec61 subunit alpha isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="13">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2452306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="476" mass="52131" checksum="70C6B34B746E7C50" modified="2020-06-17" version="1">MSGLRFLDLIKPFTPLLPEVAAPETRTPFNQRMMWTGVTLLIFLVMSQMPLYGIVSSDTSDPLYWLRMMLASNRGTLMELGITPIISSGMVFQLLAGTHLIDVNLDLKTDRELYQTAQKLLAIILSFGQACVYVLTGLYGLPSDLGAGVCVLLVVQLVVAGLIVILLDELLQKGYGLGSGISLFIATNICESIIWKAFSPTTINTGRGPEFEGAVIALFHLLITWDNKQLALREAFYRQNLPNIMNLLATMLVFAAVIYLQGFRVEIPVKSSRQRGMRGSYPVRLFYTSNMPIMLQSALSSNIFLVSQMLYSRFSDNLLVRLMGVWEPREGSAQLYASSGIAYYMSPPLNFTEALLDPIHTAVYITYMLVACALFSKTWIEVSGSSPRDVAKQLKEQGMVMAGHREQSMYKELKRVIPTAAAFGGACIGALSVTSDLIGALGSGTGILLAVTIIYGYFEIAAKEGDMAGLKGMVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLE1</accession>
    <name>A0A6A6NLE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_375464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLE1"/>
    <dbReference type="OrthoDB" id="302966at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16536">
        <property type="entry name" value="RING-HC_RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000512">
        <property type="entry name" value="RING finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039739">
        <property type="entry name" value="MAG2/RNF10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983">
        <property type="entry name" value="RING FINGER 10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="224"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="395"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="602"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="767"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="632"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="773"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="812"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="838" mass="88810" checksum="1379BDC252FFE9EA" modified="2020-06-17" version="1">MSSNSPAAVAASGKSAAAAAASSPAQSQAGSAASGDSHCGGGGGGQRRAGGHGSFGAGAASRASSAAAPRNNQAARKQHKGSRKYRFADEDALAESVSRVPRPPRGTAPAGGRLTVSPKAAMRSANSRKGQTSITHLMNFSLPPRPSQHGHAPGHGRGYRRNPTWGLGSGYHAVDKARYVHANYRFIVDPRADYLAQSVDADVHLDWGNVLQILASSQSQDASCPICLGHPVAPRMAKCGHIFCLPCLIRYMHSEDDSHPLPEKKPRRKACPLCWDNIYISETRPVRWYAGQECPAPREGDDIVLRLVMRSAGSTLALPRDGADALGKDVDVPWYLAAEVMDYARIMKGSEDYMEQQFDAELCELEMQGKEDELLFGEDNVEWSRKAIRSIHDAKEKVKGIGNPPLMPQKPVEAKKQRPPIKFNEVDESSPEKYFLEQSSAGSSTPATQPSGTPGPSTSGTSMVSASASAPRQSAEKLPSASPSALTTSLAQVRTQHGNQHSHTPSEYFFYQALLHYYLSPLDIRILKSAFGAFAAFPSTILPRVEHVSTGHVVDDDLRRRTKYLAHLPRGCEVAFLECNWEGALPGEVLERWRPEIERRRRARREKELKEEKARRRGEVAGGEEERRWAAARRNGAATGTVGPAAESPSASVSAAASSAAAAAAAADDDEEFPVASGSSPPRPPSWPPARGAVGGAFASLASSASPGTSPEAPRTVWGTAAVHPVEEQLVVARDSLPTGSEEEGDDVHVDGWLQGWERDLLVGGWEELDGGDQWGGAKSGGAGAGGGDEDVGRGAGRGRDAGAGAGDGKKGKGKGKGKGKGKGKKITLMSTNGRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN6</accession>
    <name>A0A6A6NLN6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_405261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025639489" evidence="8">
        <location>
            <begin position="27"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="9">
        <location>
            <begin position="948"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="9">
        <location>
            <begin position="1067"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="9">
        <location>
            <begin position="1245"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1185"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1340"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1394"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1394"/>
            <end position="1432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1549" mass="164240" checksum="10195E1D338BD648" modified="2020-06-17" version="1">MRAASLPAHSLFYFLVCFLFICNVLALDASDTYRDADLGQTSYVGGDHNMDPAIVDSSQFGLLWKIPFNNKERFYAKPLVYTPESTGRQIVFLASTQNIIRTVDARTGELINERQLDEPFLQSDIGCTDIPDTIGIVGTPTIDPNTDTAYFYVKTYIANFRTEGEHGVVNGVYKFYAVDVKTLEDIDPFPILVDGSIADNDDRRYFVGGVILQRVSLVQLGNYVYAGFGGHCDLFNYTGTVLGVDVTNGDIVANWAVQTGPHTAFSTDYYEVSGMGGIWHGGSSFATDGSRLFFVTGNGRGHENDGVPASGRSGCKTLGEAAVNLNVGDDGSLSLVDYFQPYDFQNMDGGDQDFGSGGMSLLDPDVFYGTGVTRMGLTAGKNGKIYVLNADDLGGYKMGSGGTDGILQTIVTNRAVFGGAGTYPGEGGYVYYTPVGYPTYVYKLGHDESGKPVLSQVGQSPETSAGRVGVGIPTVTTNKGQAGSAILWMTDPDAGMRAWYAVPGEDGLLKSIPMPQIGGVNKFQRPAFGNTRFYTTDANGVLYCIGSPVNLPLNCTAVDFGDVPLGSSKEAEVTCSVLIPIDEVKYMTVEDDRFEIDNATLPEGPLAEGDQFSIPVTWNLTTADLENTPGASYGYVTPGIKSTPLTIFTTNGVDGYVSELPVSLSGNIVSEDPYFDMTPTTVDFGGLVLGLPGEEPTNSLPFTFANRGSSPLIILGYAYTYDEAVEEGGEESDAVWTNCTQTDGVWDLGEGFTSSNLPAIDAVLDANSELSVTGTFSAVRGVDAYHSYFKAFTDGGDKFTILEGSASTAPKANFSISTAEGGWLPESVLEMDFGAVSPGNTAERIIRICNNGGSPLTITKSKPPVGIITAEVPGVDFHEGQNINIGECAYAPVIFEPEPQQANVADFEVTDSWTLNVNDLDFGVHVVEMVGIVRSDPAGPTYENGTALYTYLGCYQDGPRILPEGRTPDDHVMDISICTQACYDEGYIFAGTEYNYECWCGNNPPPGSRFQPEEDDRCTFTCTNNIDQICGGNGGYISVFYDSSRYTPTDYVFDPDDGPSTVMSIGAYEYVGCYSEVAGRALSDKTVAAGELGGSVDYCEEACRGYKYFGVEYADECYCGDTLKEGSELVPGDTPEDTGCDMQCGGNLTQYCGGGGRLGLYELVDTSTISSSSLVASSTISSSESSTQSVSVSSSSGVDITASTTSSSVASTSDTSTSSTELSSSTTTSSSATPTGPTVVPSAGEFTHIGCYIDSGPRTLHDDDLSTEEMTVELCADFCSGYKYMGVEWSRECWCGNIIDHDGAPAENGCDMTCAGDSFQYCGGSMRLNLYVNETEHASSSSSTATSSASSSTTDSSSETDSSISTSSSSSQEESSTTITTAISSTDYLTTTGTAATSSSTSATEGSTSSSDTDSSTHDVSTSPTAPTSTSAEFSTGTATSSCIPATPTVFECPEANNTLYAADDVVYRIECGVDYTGGDIPGGSKGTGSFKECADYCSTFDDCVVFSFNHWPKLCYCKNNVHTANDYGHVWSGKKLEEEDLGGVTICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM82</accession>
    <name>A0A6A6NM82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Snorna binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_328433</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM82"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="625" mass="70203" checksum="603D6EE188A6A236" modified="2020-06-17" version="1">MAEGGRVRSLFTLFRNLLLAAVVYTTVFGVVELFRNPSITHRGRLGIPDKSGPADIIKTTKTGVKVQFAGASKAVTINPHANVFNRPVSAVRPKDDFLGQRPHVDTEADLHMLVEECRGTYNGLEKMRNVFECLKFLAEGEERYYYLPPTEERASNQDPREAEYNDADGHDNTLSSYVDLSQALAPNKTSPGTCPGPIIPYHTYWTGPATWRVEVFIKSYLYTQNLACSRLYIWLDSDRNPNAVDDMLNRDALFARFLPLVERGDIVLKAWKFPQRIPLPKDEDNTDGVGYYKTPGKPNAKGEVAIADGIVEDAAGQQWLVLTPKQMTFLPVAISDAVRFVILHLYGGAYFDMDVLMLRDMRPLLLPQEHSFAERWAAHSHPGDYNTAIMSLTANSSLSSYLLRGGVRMGLNFHPRVVGRMAWKDGRDTEFLMLETAAFDPIWTEFNWDREGRCTVPCLKDYGAAFKGKKGGLKDEWQSYDGPQLESVDLEGHDARTDDTTTATTTATDGGDDVGQDPEADSPATDSFSATSDEEAALRRAGIVADYQLAEDKYPPNNRTLAHFFRGAWTYHVHNQWLKHPEPNSWIHVLQQAHSGFFAGERTNPYGERWEGPNVQAYNFWPEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM83</accession>
    <name>A0A6A6NM83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_174390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM83"/>
    <dbReference type="OrthoDB" id="3538943at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="944"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="824"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="986" mass="107066" checksum="42D4F2879CCF7298" modified="2020-06-17" version="1">MRDPVDITNEEDEDDSFLSAWSSSPVERKTNRLPADTPGSSPGKRQKMTAQFRQQQQSSPLVKQTPYSTTKTAATTSTSFHDDGLLLQPLMESSDPVIPATCTKDSSAEQQKRSASSVIFQSRSKRALGTPDYGQAEIDVQFQNEIQHAMSSQVSLRASTQDAIAPEPPRRELFLQSQDSVLDASDPIEENNELPGAEPISSNAEAVQKSLVEEIPPPRSSVLMVEDPMEEEPMANPEPTNLNSSVENLIPQDDRTASPPSTQLMVEAEDTPVDRGSSKRPASSPTKSEELMPPPARKTSKPPQKKMRVVAPEFHFSQEKQVREDPAIGMHKFKQEYLDAMSSGSSPKPVDASQSSQSVANATEHASSPPQTQHDQDSGSTEQFAQRVPDLSSLFSNGGSLFRPGLSPPAQGSPAMSTAPGMQSTPSPTAQSIYYDFKAAYPSYAGTMSHFVSLCRKLEEARRTGKAVHKSLYDDYIFRHASEYRTHVQERMSLGEDPVPYGLWYEEEVDEPGCFKKVVNANTLEVAVDNGGEGNNDTCEAGKGKRKGRLVTSGGAASLAGSKRTHGDGSSPARRSEKRLPAQRMGTPGSEFDGNVASAENSTKKAEEQEKNKGSPVTKKPRTEKIHEPVSGLPAQSIQESSPVSPPFLGRREQQVLREKRSNTRADKVEKLQASPAEEDVEMTIVSEGGTITKGKVVTSVAAPARPKPTRVSPRTKKDSMKVAEIQRQGIEEATKKEMTKEKGMRGQIGKASPINTSTALVGTVDGGLNQNSPSPLKKRTFVEVRIPVQPRTKRQSIPWLRTEKSSQYSGGDQAKRKSERVVSSKPPTTTSTNATPTKSTNSAAKAASPLPSSRAPAKHSPHPSPTVQKQSQAPQSGIAATAKNRSTSSRLASAGSNGHNVSSPKKPTKRTQPSRESEVSEDRWWEDDSTPFRQFVKHYSKVKKVRHSAPRPPVEATDALDNTGVAKGIDGGPIDVLKWDFRSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMD0</accession>
    <name>A0A6A6NMD0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_357818</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMD0"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF242">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="153"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="297" mass="33244" checksum="18FF9B02E7E9117C" modified="2020-06-17" version="1">MPAARRKSKHSGPSPARRWQIISSAIVLPAVLVYMWLSNAWSLFQFRSENPHLLCDSSQAERTSLISLDPLIIYVRDFLSPSEISALLTVAESHFGPSPVYDASARGDTRHQGRTSSTAFLPPSDFPVASCILSRARQFMGTALGPSNTSLSDFSVPQLVRYGPGQKFDVHHDAFPQPRMDQSAGRQYNRMASFFVYLEDDCVDCETWFPHVEPAGIRWGPWDTAKSNETESVMPKSDEYYRNERQGGIMFPPISGNALFWSNLKASGQQDGRVLHAGLPVGEGRKTAMNIWAKRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMF3</accession>
    <name>A0A6A6NMF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_357901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMF3"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="23023" checksum="CCB72771C571BD59" modified="2020-06-17" version="1">MSGYEEEHNITRQEPSSSRAQPRPRRGPEFFSTFFSSLDRVDTSGTPGHRQHNPHADPLPVDVSAAFRNLAEALSILRTPDAANGDLLNRLVLEMTELAEHPPKRVKGMSDEWFDRLDRVDKAKLKPDDACGICANEFLSDPYPLVVRLPCHHAHKFDLLCIRSWLKLNTTCPFDRTDFLKKEPPAKKKPDDDEEEWDGMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMF6</accession>
    <name>A0A6A6NMF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_150357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMF6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17629" checksum="C0F9149D752F9904" modified="2020-06-17" version="1">MQLQEKAVPPNAACVRQAMLTAPSTTYLSPFSRLAHTRPTGEPCPWPLWHVARTSRSRVAPWVVWPRADAGEPRGDWPRSRPSPLAPTATPTQLPRRRQRAAGPARGVHANRTCDCARSAVIGGTPTKEVQALFLYAFFVLPTPPPIAIVYPSLRSRHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMP0</accession>
    <name>A0A6A6NMP0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMP0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025543951" evidence="1">
        <location>
            <begin position="24"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="76" mass="7778" checksum="C15544B541C0E824" modified="2020-06-17" version="1">MSGSSLARAAAVSLSIIAAVTLGCRLLREASASVASELRDERVEEEGEEGAGVRSCVSGGACSAWLEEPDGIRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMX3</accession>
    <name>A0A6A6NMX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMX3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF29">
        <property type="entry name" value="SERINE_THREONINE PROTEIN KINASE-43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="103" mass="11030" checksum="2E9548DF682C0408" modified="2020-06-17" version="1" fragment="single">LSEHQVKTVLYQGLLALEHIHANGVIHRDIKPANILVKATQPFVTALADFGLASTSGEKIFKSHCGTPAYCAPEIYDELCGSGSSADRSCWSAVDIWSMAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNB5</accession>
    <name>A0A6A6NNB5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial distribution and morphology protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial inheritance component MDM10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MDM10</name>
        <name evidence="7" type="ORF">BDY21DRAFT_141689</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion outer membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MDM10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNB5"/>
    <dbReference type="OrthoDB" id="2103793at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03102">
        <property type="entry name" value="Mdm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027539">
        <property type="entry name" value="Mdm10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12519">
        <property type="entry name" value="MDM10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 6" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="419" mass="47170" checksum="AD0C054A1907CA75" modified="2020-06-17" version="1">MLDFMDYVQHAFYKSSRWNQDNSYSSLTATVQSLLDFETPRGLRLKLSSLPSPNFASSYTIGSVGLVDGSVSYLYSSLPLNVNSRSPELDLHDVVQGYRHLQDLRKPDDPRWWELWHRGRRIDRRAALLYGRFYLPRSSLEALYLRRISPTRQLKISCVSDNYIPNGGTLLAVLQEDQGKYSTEYLYSTDSCLLGWRGLYNFGPDPRDPAVKPESLGAAVSEATLPSSELYASNNNYGRFSAGAELYYGLLNKSGGMSTGIRFTTLPRHRSFPYTMTLTLNPLMGNLSSTYAVKAGPNLAMCSRFDFNFYSYESGFQLGCELWRRQGNRGGGGGGSNGEGGAEVEWAAKKMTPEWTGNAKRPDDDVSGVLKARVNERWDFGVLWEGRFKELLFTLGASFDLKRREQIFRAVGLELQYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNJ0</accession>
    <name>A0A6A6NNJ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_147546</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNJ0"/>
    <dbReference type="OrthoDB" id="5364404at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="331"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="365" mass="40059" checksum="D3AD1E4461644FD6" modified="2020-06-17" version="1">MFSSSLGRVARSTGSITTPSSWAPRVPACTGASASAAARRPLSRKAHQRRYSSSKACPPGNSRGDNSGQQPAGNASANGATDDSSAKPSTSSRKRAAKAQPLAGMATLNLPSVPSTSHVDPSDIVLSSFFSMHRPISITMSVPPSSTEASFNRIFESSSPSPQRRSVGEVLETLTGALSSLEEGMQGRPAPGKGRKRRPLTVQIVADQDEHNEIVRNRDDGQAPSPEIHDVTAHGQPFQAPPVPRSRTIRGGGRPTKKTYSTTIVFTESRYPDGRVTVVAEPSPMKRLHKGEQNVVEPGVQKVQIRQPFLNRMRIRQQKWLDQRNQAGEYMAISVKRQRKMKMKKHKYKKLLKRTRNLRRKLDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNW4</accession>
    <name>A0A6A6NNW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Cytochrome b mRNA-processing protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_355772</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the CBP4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNW4"/>
    <dbReference type="OrthoDB" id="5576752at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012420">
        <property type="entry name" value="Cbp4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28202">
        <property type="entry name" value="ASSEMBLY FACTOR CBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28202:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR CBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07960">
        <property type="entry name" value="CBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="107"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="37131" checksum="3606846AB263E585" modified="2020-06-17" version="1">MCGGAVAVHSRVAAAARRPSIVAVDDITSPRARPWADVCFPRPLDLRAPLSVSPRSRLVLAAGCAIATLAPRHHRRHQRCATAHTLPAPAPRSVIIIITITHHYCPTEPPSQKTGSPTPPSLPPSFLSHHAAGWHLGQSPHSVKSRETPRCHPPKPTSPPPSRLFPSSSPASRARPSSAGRAARLWRAGGCRCCLFPARRASLSVEGVGRTGEVDERLSECLTDWSDGCSGVALCVGGPMLVSYVTPTEEELFKKYSPELQKRSLENRDRVAQEFDDYVTKLKEYSKSDKPIWVVQAEELKKDRKMAEQVARQKRESVAAEMIREKAEIKRQIHEAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNX7</accession>
    <name>A0A6A6NNX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_357261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNX7"/>
    <dbReference type="OrthoDB" id="4161186at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="2">
        <location>
            <begin position="215"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="508" mass="56476" checksum="66549D9BBFF69A81" modified="2020-06-17" version="1">MRSAVISAWQHDVAASAAAYSGSTPPPTGRKRPHLSEPSETSSNQQSLKRRRVALSSIAINPRNVSAHTKDRSPSKRTRAPSPRKRGNNGSDVATKELGTPRTRSQPPIPRFDPQSSYREALAADSDESEIPQPRSPSRPAQTESDAPSTSKRSTSPVKRVAALQDVGSGIFYRELSDNGTELGTEGQELFWLLQDSSLGIAALPAALEPELLPEQGRIRPFQIDTTDLRSRDELLAELETVREINRASRRCVRDSESEPEWNNSVHGTLLRLALRKEDRAGFRYITTARIDPQYVPAHSSGLGMLSKMVDYAIYLETSGPSSFDLSTSSPLHERISALITDVTHSINHTSYVSLRHRPIAVSIETKTIGRPEEEARVQLAIWVAAQFERIRSLFTETAYPASIPAPTKASRRKNPKALSEELDRNAVLGRIVFPLLYVQSVQWTVLFARPSPSPLADRSVTIFSSIILGETSSLLGAYRILRGLRVLEQWIDTTYRNWWKELLDVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPR2</accession>
    <name>A0A6A6NPR2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_355030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPR2"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF480">
        <property type="entry name" value="PALMITOYLTRANSFERASE SWF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="161"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="353"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="468" mass="52454" checksum="63A0648FA5F7AEA5" modified="2020-06-17" version="1">MGTLRAVALFVLTLSFLTFVALFGRLPALRNTPIGFVHRLIWIHIPNFAQRIDIILTGGRGSRAGARFSHYLLYQKHPLVLIFFLGLLTGSSALLLPVIWPRLSASLRFPVVLLLPLPYIFTYLCVYPPTPFSPHITPTTLSSHLTHYPYDYTLYHDFRPPCRTCLKPKPPRSKHCNLCGTCVARADHHCVWVNNCLGRGNYKFFLLLLLTSSVTIAYGAYIAWAALAPDVTRICVAMASRRSRLRDGRNMFESFIPAFALQRFRAAALGLSIAVDVGGLRVTGVGLLAVLTAPLPLGLLVYHVRLIHAGTTTNESSKWADLGEDMREGIVFVARVRKELRWGSVEDEDDERGRWKGEWVRTEGEEGTGRDEITDVEDSSEEGSSDDGASANNQVSHRRLLKRQKAAWPLGPRQVAIRCVSGLLPDELPPELADLVEPGTWQRCWKLVDVDNIYDLGFWDNLSEFLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ86</accession>
    <name>A0A6A6NQ86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Translin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_292130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ86"/>
    <dbReference type="OrthoDB" id="31005at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="29209" checksum="47EB0256171B046B" modified="2020-06-17" version="1">MTAPTSPYTTMFEGFRAELDEHYDRRERVIKASRDLTSASKRLIFALQRTRSLARPLPSSVTKAAEPHHGATGAAHDALALELSNSLRAHRYAWQVSPGLQEFVEAATFGHYLRHQTLMSFDEVQKLWTETGEQGQGGEGMLQYSDYVLGVFDLTGEMMRWAVLMVAVWGSAPSRDADEGAPEGLRDVLRDMRDMRAALEALDVPRGTPLASEIGKKTDVMKQSVEKVENATYGLVVRGRERPEGWMPDSGGSAEGRMEVDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQF4</accession>
    <name>A0A6A6NQF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_291947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQF4"/>
    <dbReference type="OrthoDB" id="4415650at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="11766" checksum="891267C802754B7D" modified="2020-06-17" version="1">MSTPILFTIDGSGRHEVISLKPSSTSMANLSSAISGAAAGSPNCEEFMSKYKSAKEESVTQVRVRWCTAGRDSKAWPSSTILHESNCAAVLSLMDPAKDTLEVKMRAQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQS8</accession>
    <name>A0A6A6NQS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQS8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="122" mass="14159" checksum="92EDB9224C2DBCC8" modified="2020-06-17" version="1">MRFFFCIENTPTQKCRKVENTSRRKVKNRPRPRPRPVVTDRTDVRKETSPTNETKETVQQARNAPRQPEPRQNKRTQASSQPSRTVPYERKIENPINIPNRPQSSPPLPANRLPLSSHPLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQU1</accession>
    <name>A0A6A6NQU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_366612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQU1"/>
    <dbReference type="OrthoDB" id="5338195at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140849">
        <property type="term" value="F:ATP-dependent H2AZ histone chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037651">
        <property type="entry name" value="Swc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057558">
        <property type="entry name" value="Swc3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28108">
        <property type="entry name" value="SWR1-COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28108:SF1">
        <property type="entry name" value="SWR1-COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24707">
        <property type="entry name" value="Swc3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWR1-complex protein 3" evidence="2">
        <location>
            <begin position="69"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="852" mass="89738" checksum="00306FA693635408" modified="2020-06-17" version="1">MVDKRRASTRAAAHPSKRRQSAAAATKDVAATSEDTPMPDADALAQDEAATGRDKNKLKKKQHEPVELPDKVVEGRPLPTVDEPQQLTTTELLGGQYQSVANSGVLAASLQRSRSKWAAEGVFERYWTKSNKRKSQGSSVDGTATAADSNKRTYSRRVGTCKLIIEPHMFDCNIWIEPEPPSSTSHAHANHAHHQAPNGGQIMHPDGRPQMQYGPPNGAIVTPPPIYSNPKQARPQYAGGPLPQYRPYPQPSPTPQQQCVQQQPQRASPYPPTPSPQPTTHQQQQQQQQHQHQQQRQPSNPPNEPATQPAGSSAPSPAPSTTSATPNPPSKPNAHSAALSAPNTSTSNPPQSSNNPNPPPKSSTPTPGGAAPSSAPASTPKPSAPTPSSSAAKPPADPVIQMLADRASQDPQLKAVMKIVATGNATQEQLEFFQRHINEFTRVIEERKARGELPGGGTQGQQQQQQQQKPLQQAKNSTNGNGHGNGAGGAAARQQHQGRQLAPANANANANATAPPQQQPPQQSPAPSASAPSSGPDATAHHRNTPSSATPTATPSVRPGPPSSTSMSRSPSAGTAATSGSRAVTPSIGGTPVPAVGQAQQQQHQQQGRQHGSSGLMGAQGTGGGRGKNAQHGHHAGAGAGTPQKALSTHNIANVQQRNASSSYGHHHHGPISGDIRALLLEFTTGGDRFLFPKYAVLEFQAGGRVCLASFLIVHRGSSTARTAWPSEAEGVDPEEVAARAAAERKAARARARKKARDKEGGGAEEATPAPGEQAKEKVKRKEKNEEEVSAAGGRYDPALDYYQPVTARFAAEDPACLAPLGRWVAPREEVRRSSGVCVRLSAERIPEMGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQY4</accession>
    <name>A0A6A6NQY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_354853</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQY4"/>
    <dbReference type="OrthoDB" id="3561359at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF7">
        <property type="entry name" value="DRUG_PROTON ANTIPORTER YHK8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="149"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="593" mass="65835" checksum="53D4EA0584397207" modified="2020-06-17" version="1">MTSTREFDVESANSKSIERGRSNSIADEEKRLEAGDDVIDRGRRRLEPLHTGRTHPLSKNSSRRSSRSARSQFSYAGGDGYTYYCDNPENDTGDASGDEESPKSKEESAESPSDESPSGDEKQFEVGWDGPDDSMNPKVRLSFVHKWVIVFIISSCSLCVTFASTVYTSIYIQVIPEFNTSREVATLGLSFFVCGLGLGPMLLAPLSEFYGRRPIYLVSFLFFIIWSIPCAVAQNIQTLLVTRFFGGFAGSAFLSVAGGTVGDVFAKNELSLPMMFYTASPFVGPEIGPLIGGFINDFASWRWTFYTLLIWAGVELALLFCLVPETYAPVILVQKAKKLRTETGNEKWHAPLERHERSIARTVLVSCYRPFQLLFFEPMCLNLCILSAILLGVLYLFFGAFPVVFEGNHGFTLWQVGLTFMGLFVGMVIAVACDPLWRRFVYMRLVRKREAAGGEPGGTEPEFRLPPTIVGAWIVPIGLFGFGWTTYPHVHWIVPIIFSGIFALGVIWVYAGVFTFLVECYPLYAASALAANSFARSAFAAAFPLFGVQMYHTLGDQWATSLLAFLALAMAPFPVLFFKYGKQLRSRSTFASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR52</accession>
    <name>A0A6A6NR52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR52"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="22497" checksum="8BCD91F689077604" modified="2020-06-17" version="1">MPAAVCRCGAIGEAGFVFSLLSFTLVDRAAFPFPRPRRLVIVHFCVLAPQHGDGSAKLRGRRSCGRRLVQRVWLELRHGRVPISFLIVRRAVHEPFVLDNIVTHFLHHHPRRRPSSQPSPPQRRQRLLPFALFFLLFLHHAHPAPLLYVRVRIRPELRHRGISVLVLAPVLVNRHRSGQTAPTPREDGPRDGQALGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR77</accession>
    <name>A0A6A6NR77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_107818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR77"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025658936" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="15273" checksum="ED7A6E168A76C447" modified="2020-06-17" version="1">MWMRMSLGIFACWAVTDCFGGLHGAGTAWWLLWSPKSKRCPTTYAAAQRVPCRCGPRRRGGRLAYGRVCPGLVLSSRRQGDLSDAKLVFQRHFCLHVGRRLICTIYSYLPFIYSFPLDSAWKLEFCFSSLIQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP5</accession>
    <name>A0A6A6NRP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_291534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRP5"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="334" mass="36974" checksum="DB7D7DD5FAD7116A" modified="2020-06-17" version="1">MFRFFKNHLFWSPKMPTGSFAGKTVIVTGANVGLGKEAARHFVAKGASKVILGCRNMDKGNEAAQSIVQSEKVKDAGKVEVWQLDLCSYESVLAFGERLNGLDRLDVLVENAALATIDFKMAEGHESQVTTNVISTFLLALLALPKLKETAARTAGEPDYRPPHLVVLSSGMIYTAQLPEARNKDEPIFAQLDKNKSNLMSRYPVTKLLEVLVVREWTRTRAPAYDYPVIINTMDPGLCESALRREVPRAGLGARVVVGVLEWMLARPTAVGARTEVDAALKGYESHGEFITDQEVEKVSAFCYTKEGFETQRRVWRELADILEEIKPGVTSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRS6</accession>
    <name>A0A6A6NRS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">CAS/CSE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_366231</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRS6"/>
    <dbReference type="OrthoDB" id="3268246at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1006" mass="109812" checksum="DA374F8A4C1C327E" modified="2020-06-17" version="1">MAAASSNDDLDAIGRLLDASLDPRQNKAAELALRQHQQQPGYALALLRIVASDRFAQTTRLAGALGFKNAVRAGWVDSDGNHLMAPADVAAIKGELVGLMAAVPLPAVRAQLGEAVSIIADSDFWERWDTLVDDLVARLGQAQAAPQQVHGLLEVAHSIFSRWRPLMRSDALFTEINHVLDRFAAPLLALLHHADQRARGDAARGDAKALRDDLHTVDLVVQLLYDLSCQDLPPLFETNLPAIADLLLRYLAADDDDAIKAEATVLAADGDGGDDDDDSADPGALDNVRAAIFELLVLWETHFEEELKPLLKRFMEVSWALLARTGRQARHDTVVSRDLMFLSTVARVRSEAEIFNNESALGEVLDRVVLPNLTLRESDLELLEDEPVEFVRRDVDGSAAETRRRAATEFLRQLLHHFEQLVTTMALQRVNKLLSDYSAGGENAWMHKDVAVYLFSAVAARGVPTAQHGVTDVNPLVNPLEFFSRNVAVDLTDADANSVHPMLQVDAMRFLNSFRSRLGPADWNAALPLLVRRLASQDPVVYTYAAVAVERALHLTDPASGAPAVPRQLVTPHCGEMLGQLFALIRRDPAPEKMQQNEFLMRCVMRVLVVVKADVLAAAGNPVSLTAENLVAITDVIRHNPANPRFYYYHFEALGALIRFAAPPDPSKLEAALVEPLWNVLAAGVDEFVPYVLQLFAALLDAGPAGGGLGGGAGGYAERLVQAAMQPALWDAKGNVPALVRLLTSVVARGAGPLARAGQTEPLLGVFQKLVVSRAHEGLGFDLLEAMLLHFDVEAALAPYLPMVLQILFTKLDRQRTDAFVLRFVRLFHLWCARGEAKGLGTDKFVELSDGLQPGGDVFKGVYLQFVLKTTAERLVRPIDRKVAVLGLATTLADSRAFVDRYPKGWTLTCQSLLSLLINPPTVAATSDETIPDADVDDVSFGIGFTPLNTCRRPPADPFPEVADVKQWVGTYLRERDQVHGGRIAKFVQERLGDQERAALMAVMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRY3</accession>
    <name>A0A6A6NRY3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase/reductase family protein-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_353107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRY3"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="46515" checksum="CC5E79455E1120FD" modified="2020-06-17" version="1">MSGSSKPPHLSASRPPPFPPHNAPRVWFITSGTSPLGIAVARQVLAHGDCVVAGVLPAEFECEEGRSAELREFIESLRSGNDGAAAGATGKSGTTVANMGRRLRVVGLDSRIMGQCQSAVAEAEEAFGRIDILLGCTTEAVVGAIEELSLSNRTQTLVRDQFETNFFANVNVIKAVLPSMRARKNGHIVMVTGITAHLGTPGLGIYSSSQWAIEGYCDSLAYEIAPFNIKMTIVQPMLETNVLTNRITSVPQLPQYHPRNNPAPLAREVLSRVLDRLDGGGSGSGLPPSSDQPSHPAAGHGAQGPDPDPDVDMDRPADTQQPRCCPSPTAGPSSDPSAAATASSGTSASTTPSHAQQYPPPPLMGPDVSSLYPSPPPSFRAAVTAETVYALTAIGGHDNPPARHIVGLEGVISVKDKLKNVNEELEDFLSVSSAVDIEREESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS85</accession>
    <name>A0A6A6NS85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">X-domain of DnaJ-containing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_381587</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS85"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000028">
        <property type="entry name" value="DnaJ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052814">
        <property type="entry name" value="Peroxisomal_DnaJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006:SF1">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="52934" checksum="21C6B65D72E79492" modified="2020-06-17" version="1">MVVDTTYYDALQVPPTASELDIKKAYRKLAIKLHPDKNPDDETAHQKFQAIGEAYQVLSDTELRKQYDKHGKEGAVPSHGFEDPSEFFSMIFGGEAFVDWIGEISLMKDLTKTMDITMKEMEEEENAEPGTTSATDTKTSETPPAQEAPAGETSGPSDTKSASPPPESGSTSGTSTPRPRGIPIRPAIMDKSEEEARLGMAGVTEGEKELRAKEKKKGGLTKEQRDELAAYEMERKKVRDERVDTLAKKLVDRISIWTETDKGNDVTAAFKSKTQLEIENLKMESFGIEILHAIGATYLQKASAFLKSQKFLGVQGFFARLKDKGTLVKETWSTISTAIDAQMTMEEMVKMEEKGGEDWTDERKAEYEKKVTGKILAAAWRGSKFEIQSVLRDVCDKVLNDKAIKLEKRMERAQALMIIGEMFSKAARDPDEEGDFMAFEQLMAEAAAKKEKADSKKSKKAQKETSSPHDVHKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSG0</accession>
    <name>A0A6A6NSG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_353283</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSG0"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF23">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="31334" checksum="CEB2CCCB19AD713B" modified="2020-06-17" version="1" fragment="single">MDHFCPWVGGIVSETTMKFFVQFVFYATFLCGLIVIVLAYYVDDRKKKLGDLNVGWVAVLAVAGLFVLFSAGMTMSTLWMTSSNLTTIENLNKGSQVYNIAVLLKPDAAIPNPSQPGANQDAGTAPGYGTITYPLLLQAHQSETARSVGPESSSSRPSPPRRTFAVLSTRPGMNPWDLGSVWANLCSLMGNSFDQWFLPIKPSPFAMRRRLTEYQFGPVILELVHMYRLQDAVSEDLLLDVGQGRKLGAFGRKKVHRRRPRKHEERRRRRRGTVVTPGDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSP5</accession>
    <name>A0A6A6NSP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSP5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="75" mass="8314" checksum="EE2EBCBCE5D3EABF" modified="2020-06-17" version="1">MPCRAALLCAAPVRCPTFWAFSPRPLGHPESCAGCHWLGQAPRSCELMLLMYAIRRADELRALADKSWLDSPSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSQ2</accession>
    <name>A0A6A6NSQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_387409</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSQ2"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="222"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2454588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="874" mass="93783" checksum="594B9AB6DB3ABE3F" modified="2020-06-17" version="1">MAPSFLPTFDSSILSSPGRLIPAPLSYLGHAFVTITPSDVDNALRYLQRTVGLHATCFDVSALHLVDDIVSILDSGARKVVVSGSQLRELERVENLDLDRVALSVSPGMKNEMIDAIAGTSVDLYVHRIKDVELVEAWLKEYGTDRPDVYVSFDTPSVENALRIANLSGIPVIPASQCTADPVSEQQNIPIATLLLANATTDRLDGLFTTIVTDERGIALGLVYSSHESVNESLRTGKGVYQSRKRGLWYKGESSGDTQDIVAINLDCDHDCLKFTVKQKGRGFCHLGTPTCFGSFQGLPKLQQTLQKRKSSAPLGSYTARLFKDQQLLKAKIMEEASELCEATTKEDVTFEAADLLYFALTKCVATGVSLEDIERNLDAKSTKVKRRKGDAKGSWAAQMGMPADGKVQQEVGQPHPTSSSIKASEGPGDRIKMRTFVVADGNHTIITKALQRPSQRTSDKIMSIVRPIIDSVRHRGDAALLEYAHKFEKATSLASPVLKAPFPKDLMQLSPETKDAIDVSFENIRKFHAAQMEPKPLSVTTMPGVECARMARPIEKVGLYVPGGTAVLPSTALMLGVPAMVAGCRNIVIASPPRADGSLTPEIVYIAERVGAETIVLAGGAQAVAALAYGTESVSKVDKILGPGNQFVTAAKMLVSNDTSACVSIDMPAGPSEVLVVADETANPAFVAADLLSQAEHGVDSQVVLIGVGLGDGQLRAIEDELHSQASALPRVDIVRQAIDHSVTLVVDGVAEAMDLSNRYAPEHLILQVRDAQDVAELVQNAGSVFVGPWTPESVGDYSAGVNHSLPTYGYARQYSGVNLGSYVKHITSSNLTAEGLRNLGGAVMQLAKVEELEAHRRAVSIRLAELDRLSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT80</accession>
    <name>A0A6A6NT80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT80"/>
    <dbReference type="OrthoDB" id="5327145at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="478" mass="51389" checksum="FA03AED609D64C2A" modified="2020-06-17" version="1">MFAAHDQQENLVHAQQAAAAAKPLNQGLKQFTAKTPGNKAPKTPFKVALNDENAVAGPGKSVAKANGKARDNLLRTSGLNKKGDAEKDAFVTPAGPRTARAPLGAKTTNAKAKPLQTPAPNNLEPGTEKTNVKSRSPRLRRPAKLKVLQADPEAASANLHDEEPDVEYMPPRGVPLPDFDDDDVPAEVKYPMLAGKNLTRGWASTYLDPLDDDDVPLSRKRAAENKVRADAYADRMMAEAFGSLPGPGNRTKRPQSPGKKNVPKKQNEPAKKPPAGHQRTGSTQSRASRADTATSRAAAAALAQPNANPNTSVSHAAPPKPRGTAGFLRPRKQAAPEPPANAARRHALATAASRTTLGYAKGRDASSNLRKPVRNITRGLDALPGTSEPVAINPRALLRREDSEMTITPARYAERFQQAEEEEDEVVRDLRAMDEMMRCGAEDDGVEEEVTAALRGRTEEDLGGLDDELEDFQFDVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT90</accession>
    <name>A0A6A6NT90_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_308350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT90"/>
    <dbReference type="OrthoDB" id="2590011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="28"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="211" mass="23424" checksum="006CE125EE2C856D" modified="2020-06-17" version="1" fragment="single">MRNMKFTFRPYKGSSKGDDDPEAPEPSQNPKERRREQVRRAQRHHRERKEAYIKSLEAEVVQLRASEANIRKQARHLYSELGFLKSILVQNGIPVPSSSEQIPEPDPGPYEPSSDASFVLSVQEKGWTGKQLRAQRAGSVQPEEGLLLSDSSGVSEGQRQPGWRRRGKDPVYPSTSQSPSGSSAARATSDVSASSPKPLPPTPQQQPHFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT98</accession>
    <name>A0A6A6NT98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Onanonoxo-7-onima-8-eninoihtemlysoneda</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_325496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT98"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000080">
        <property type="entry name" value="Bifunctional dethiobiotin synthetase/adenosylmethionine-8-amino-7-oxononanoate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="800" mass="87186" checksum="B69622DB418C31E2" modified="2020-06-17" version="1">MLRPPPGLWPNLVAAQIFGAHTGVGKTIVSALLCRTLSETHPSYAVHYLKPVSTGPEAEADDRHICRFAGKRTQSKCLFQFSLPVSPHVAARLDGNVPSAESLIGLVSAEFSKYAKEKNAVAVVETAGGVLSPGPSAESQADLYRPLRLPVILVADHRLGGIGTSLSAYESLRIRGYDVDAVVIFKNEENGGILGNHEYLSDFFRKEVKDNFFVLNQPPAPVLPVEEDQKNVETYYERAVRDKKLGPLATLLVENHKSRIEKLGSLVVAADKAIWHPFTQHQGRSTKDILTIDSAYGDFFQTLRPETSLETSTNPLLQPAFDGSASWWTQGLGHGNPKFSLAAAYAAGRYGHVMFAGAVHEPAVALADMLLAESKNPRLSRVFYTDNGSTGTEVAMKMALRASAARYRWDSRSDDILAIGLKGSYHGDTIGAMDMSEPSTFNEKVEWYRGRGFWFDFPQVQMRNGAWTIEPPTGMESEFGPPQTFGTLQEIFDGSRIGEKYRLYIRDVLTKLVRDGKKLGALILEPVILGAGGMVFADPLFQRTLVDVIRKEPEIFNTYPSSGAPSDSNAWAGLPVVSDEVFTGLYRLGHWSASSLIGVDPDIVVNAKLLTGGVLPLCTTTASESIFEAFLDDDKSSALLHGHSYTAHAVGCTVAITALKEMKGLEASEGWEAYRLEWNPGLSDKDVVSPSPRAVCAKASSRIWSMWSQDFVSQLSYKTSVDSVWALGSVLVIKLRDVHGQGYTSNAAAGLQKHLLNGQAGESWSIHSRVLGNVLYLMTSMQSSPIVLKAISFAVLEALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTB4</accession>
    <name>A0A6A6NTB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.282</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_291040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TYW3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.282" evidence="2"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTB4"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA wybutosine-synthesizing protein" evidence="10">
        <location>
            <begin position="7"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="266"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="33730" checksum="31659E05C8B97928" modified="2020-06-17" version="1">MDQAFEEKKRKILDQLSAPDDAYADLSPKGSVDEAIRHLISDTNRVNGLVTTSSCSGRVSVFLEGRRKDGLSVTHNADGDEATTTAGPGGKGGGSWLYVSHEAVGMPAEHEDTYFHSLFGLASRSSDQPIPDGDALRYARFKFEPMILHILARSLQDAQKVLSAALSAGFRESGAVSIVPTRAKETMPTVAVRSSGLMFDAPVGLCAPSGLVMSIVTEAYLRHLVSIANDRFRVNSERTERFKSALLDQFSLCSLKELGGREKVEDAEARKTRKRAEGLKVQEESRFQKSEPMPAVDISEIGNIFRETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTE5</accession>
    <name>A0A6A6NTE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_77046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTE5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="215" mass="23257" checksum="874703F73D057D75" modified="2020-06-17" version="1">MTSSVPAGTQQTSSPAALPVDPPRPHPAGRAKPPNPLVSPYCAAPAVLQNFSPRSGHIVRARDWDLGFLGRHVTKLGGRHKPVVAGQKNQEERKEQKSGNSFNMLNAEKRWKRKGINWRSRLPDWNSDPLRTNQTRVGASCFKLIWLPIGGSGRAAQALSMAIYSHASGIGHGNVLAAVFRNTPVDRKNAGAWSILSLTCRSGAPPWFCSPVDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTL8</accession>
    <name>A0A6A6NTL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_96710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTL8"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000067">
        <property type="entry name" value="Transmembrane domain transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="110"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="512" mass="55866" checksum="74A4D3D640E641B3" modified="2020-06-17" version="1">MSSPVAGAGAGAGGAQPRVFTSNFIEFLSLYGHFAGEELEEDDEVLGPDEYFSSDAYAEEEEGEAEGGPAAGHGYGEGGSDEEREPGEDSTLLTPGGKRRRRRRIKVTGQGSAKGAALLLLKSFVGTGVLFLPRAFLNGGMVFSNIVLLFVAGLSYYAFLLLVSTRLRVEQSFGDMGGALYGRALRNLINFSLVISQIGFSSAYIVFTSENLQAFILAVSNCRTHIDIVYMILMQMIIFLPLSLYRNINNIQKLALVADVFIVLGLVYLYYYDIFTIVSQGGLGPGIAPFNRDDWTLFIGTAIFTFEGIGLIIPIQSGMKRPDKFPGVLGGVMLAITVIFLSMGALSYAAYGARTKTVVLLNMPQDDRFVNAVQFIYSLAILLSTPLQIYPAIEITSQQLFSRTGKYNPYIKWKKNCFRFCMVAFCAVIAWAGAGDLDKFVALVGSFACVPLVYIYPPMLHYRAVSHTRLQRLADVVLGIFGVVVMAYTSVLTVSSWVRGQSSKAPGYCDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTP3</accession>
    <name>A0A6A6NTP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase ROK1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase rok1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_352339</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTP3"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="230"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="500"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="674"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="685"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="699"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="709"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="741"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2454643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="752" mass="81694" checksum="3A58941339A3D9EC" modified="2020-06-17" version="1">MDAFKILSRSTKLSTNSPRKGSASKTPSSGQPNTPQLFGRDVATSAESASRKRKREGQGTASGKVADSVVPDLDIFPLAENFDNVPALGSGVAPQNEVTQPAGSSVTSVLLAPEEGGQELLSEGECKRLLRLHKLKVTLLQDAEITKSMRTQEAGMAKRTRSQLFPQPLVSFNQLESRYSLNSKLGANLRANGYTVPTEVQLGSLPLLLQSQPRRQHLNSPNMVPDDADKKGLHWDVDLLAVAPTGSGKTLAFLIPVVNALAKERSPPLHMLREETGKGGPVAVVVAPTKELANQIVNEARKLALGTSLRISRLRKGQRISAPRAEDNTDGGCEVSSEESNVSFGGNTACAARSNLCKKGAKKQPILKADVLVSTPLLLLSAIESGPNNTSPLSTVRHLILDEADVLLDPLFREQTLKIWYSCTHPLLRVRLWSATMGSSIEEIALTTINDRWNRLPSTAKKSVQQPPVVRLVVGLKDTAVPNVAHALTYAATEQGKLIAVRQMLHPTMPSAGTGPVLRPPFLIFTQTIQRAIALHAELLYDIPAEAGGRARIAVLHAELSDTTRDEIMTRFRLGEIWVLITTDLLARGVDFRGVNGVVNYDVPNSAAAYVHRVGRTARAGREGGVAVTLYTKEDIPYVKNVANVIAASQKSRGACEGELHGIERWLLDSLPTPSKRDKQRLKKRGVEARRPDHYGKNASKTRISTKSGFERRIESNRKGAIRGTKNRTQHDRRSGQDLSSADDTDFVGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU35</accession>
    <name>A0A6A6NU35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_72380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU35"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="641" mass="72207" checksum="BE5EF7CC85DA7F5C" modified="2020-06-17" version="1">MIALWIAIVSVVAYILHSWRCLARNIAAAKRSGLPYVVQPIYTFNRAWLVTHRIWLPLLRKLPSAWTCPWIEFLDPDWPWSIKFNPFEQLGCDVFLAVSPKKCAAFVGSPEAINQITARRNDFPKPVWLYKNIDVYGKNVVSSEGMVWRQHRKITSPSFSERNNGLVWEETVHQVQSMIAGWIGKGPVGAKTIQSPAADAMRATLHIISRAGFGVRLLWPHEESGLDRCSVKRDGYTSTNTPSPGHSMSYSHAMTQLLENVMWIPVLPLWFLARSPFRVHRLAHEACVEWGKYMVDLYQTKKNQLYCGDAEATGGMDILGAMIRGSGLKPEHSRPNNSQKSQTSEGQMLSDSEILGNAFVITLAGHETTSNTIHFSLLLLALNWDSQERLQKDIDRILEGRPVEEWSYEQDFPKLFAGMPGAVMNEELRLIPPILLIPKSTPDDAPQALTVDGKQIVIPAGSDVSLCPMALHRNRKFWPSQPDLDYFRPDRWFVKPAYGLSESPSSDDLTPNAEPEELKPSNGSDVPRSHYQPVKGAFAPFSQGHRSCIGRRFAQVEVVASLAVIFRDYSVELAVDEFASDEEVAKMPPGGAERRRVWQMAAGRAEDLLKNNMSSIITLQMRGAHVPLRLVRRGEERFVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU86</accession>
    <name>A0A6A6NU86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_73599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU86"/>
    <dbReference type="OrthoDB" id="4083871at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077:SF1">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="11887" checksum="D46D9D6774F97139" modified="2020-06-17" version="1">MGALGNLFPLVVLFIVVGVGAYVGYSIYLWSNELTDRGKRKLEKKNVVFSKNGMKVGVKEVRTEDYEDKTQSVLVKAWNLASFPAYKSRLGWNSEAETNQKKKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUC4</accession>
    <name>A0A6A6NUC4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannitol-1-phosphate 5-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_290105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19661"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:61381"/>
            <dbReference type="EC" id="1.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the mannitol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUC4"/>
    <dbReference type="OrthoDB" id="418169at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008926">
        <property type="term" value="F:mannitol-1-phosphate 5-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019592">
        <property type="term" value="P:mannitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00196">
        <property type="entry name" value="Mannitol_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023028">
        <property type="entry name" value="Mannitol_1_phos_5_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000669">
        <property type="entry name" value="Mannitol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002652">
        <property type="entry name" value="PRK02318.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524:SF0">
        <property type="entry name" value="ALTRONATE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524">
        <property type="entry name" value="MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00084">
        <property type="entry name" value="MTLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol dehydrogenase N-terminal" evidence="8">
        <location>
            <begin position="6"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="206"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="387" mass="42964" checksum="908A86EEF547904F" modified="2020-06-17" version="1">MYEKVAVHFGGGNIGRGFVAEFLHKSGYEVVFIDVMDSIIEALQNSKHYTVTEIGEDGERTFDINHYRAINSKYEEAKVVDEIAKADVVTCAVGPNILKFIAPVIAKGIEARTVDYPLAVIACENAINATDTLASFIKQKLAEETLATLDTKARFANSAIDRIVPHQDPDAGLNVKIEKFYEWCVELPPFQGAPHPEIDGVHYVNDLTPYIERKLFTVNTSHATAAYYGYNRKKALIHDAMEDAEIHDIVRECLRETASLIVAKHGISAAEQNDYVEQIISRISNPALEDKVERVGRAPLRKLSRKERFIGPASQLAERGMKHSSLLGAVEMALRFQNVEGDDESVELAKILKETDAKEATTKLTGLEETHPLFPDVKELVTKVQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVR0</accession>
    <name>A0A6A6NVR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="2">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">E2 ubiquitin-conjugating enzyme 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ubiquitin-protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_386932</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="2"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVR0"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23796">
        <property type="entry name" value="UBCc_UBE2G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000008">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0882">Thioester bond</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="17">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="15">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00077195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2455584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="18723" checksum="D7DB9ACB6D722F1A" modified="2020-06-17" version="1">MSSAVAAKRLLHEYRTLTNDPPEGITAGPVSEDDLFVWEALVQGPEGTPFEGGIFPAEIKFPKDYPLAPPQMRFLCEMWHPNVYPNGSVCISILHPPGDDPNHYEHASERWSPIQSVEKILISVMSMLAEPNDESPANVDAARMWREKRAEYERIVRENVRRGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW39</accession>
    <name>A0A6A6NW39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">20S-pre-rRNA D-site endonuclease NOB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_365414</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NOB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW39"/>
    <dbReference type="OrthoDB" id="446759at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000020">
        <property type="entry name" value="20S-pre-rRNA D-site endonuclease NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.10">
        <property type="entry name" value="Nin one binding (NOB1), Zn-ribbon-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017117">
        <property type="entry name" value="Nob1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036283">
        <property type="entry name" value="NOB1_Zf-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014881">
        <property type="entry name" value="NOB1_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08772">
        <property type="entry name" value="Zn_ribbon_NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037125">
        <property type="entry name" value="D-site_20S_pre-rRNA_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144206">
        <property type="entry name" value="NOB1 zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ribonuclease PIN" evidence="11">
        <location>
            <begin position="14"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Nin one binding (NOB1) Zn-ribbon-like" evidence="10">
        <location>
            <begin position="362"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="114"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="422"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037125-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2455687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="519" mass="55615" checksum="29DCE1ACD2128D38" modified="2020-06-17" version="1">MDAKLETAKPVHSLVLDAGPIISNSPSVSTLLAHSEQLYTVPAVLAEIRDAATRSRVETTLSPFLKPRAPRAASVKVVSDFAAKTGDLAALSGPDLQVLALAYELECERNGGDWRLRRVPGQKGLNGPKPQELRDKERKEKQPKGNEEAKEEAKGQTEVSSAVSLENTPPDHAIATDERNSRDPLAESTFETFPKGTAEMIRGSEKADQVEEAAPEPEKSDGQEQPNGVPQQADTTGDLSNAASSMTISATTADENVNPSNSPTVTNNNNAEYQSNPTKQESQDAISLSSSDSDSDGWITPSNIKKHQLADMTGSSRGATQQPPAHMAVATLTSDFAMQNVLLQMNLHLLGSGAGSNALPRVRHLRSSILRCHACFATTREQARQFCPRCGGPTLTRVGCSVDAETGRTRLHLKRNFQWNNRGNRYSVPKPVADSASGKAGGGKKKGSGGGKGGWGQDLILAEDQKEYVRAVQQAKREKKRDLMDEDYLPAILSGDRSGLGGGGRPKVGAGRNVNSRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWK1</accession>
    <name>A0A6A6NWK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWK1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025347390" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="7782" checksum="D5C66DAF24AE512E" modified="2020-06-17" version="1">MLFFLPLLLSCLARFSCSSLCSCWPDLLLLLYICRPALAGFASSDGEIPQYPTSAAALAAVRARTRGREGGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWM4</accession>
    <name>A0A6A6NWM4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_372739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWM4"/>
    <dbReference type="OrthoDB" id="5135333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="209"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="789" mass="87628" checksum="1E1B510C4F233ACB" modified="2020-06-17" version="1">MLCSKCTSLKLTRTDFESPPFVPDDKYGKVIAAGTLGELRANEARCPLCRLILEALGRNERSRDPRPLPDEADVASWEMSWSQNNTEYDPITAESETYYGSALYPKLNKAGSTESHAIQLVDGGGDGTGPASGSRGFLRGRSLAEHVDLDMARGWLGRCRKEHGQSCVKTYLNIPAHPAQLPGFLVIDVQKYCLVPLPFSSPAERVSQYAALSYVWGQTNRPVATKATLAQFSEPGAFQRVLVPKTIRDAIEVTRELGLPFLWADSLCIVQDDKNTKDLLISNMDAVYGHAELTVVAASGNHAQAGLSGLAGSDSNGRMFPMEDLGNGLHLGVLTELADELMNCDHAKRGWTYQEGCLSSRCLVFLNGMCSFHCRAAVWREDVMAETDLVKPFESANTLGRTMNPAPLKRYEQHLTAYLERNLTYPSDALNAFAGIQKATATSLHNTRVWYGAPAAVFDWALLWDSVLKVTRRELFPSWSMMGFEGHVLPANVSWPDDDQRWLLHRTWIEWYIVTGDGKVELVWHPERDDAAISPLVEEALKERSIETNQEGEQLSSDVDEVVTSDDEDDVEEEEDCPTYGIPLAGNPYGRSMNNRFLSQNSSQPRSETFTTTKMRLPLGTLCFSTLSVCYRVLPSKLVTHHRQESNTLLLCDRDNTKCGIIWNSTLPKSTPDTANGKSEPHELILLSYASPNTTSELDREGAAEAAGLDRPYWPSKQLPGVDGEHIGPYWHAWDYFNVMMIAPKVVDDDDAEGGRPCLSERVGLGLLHKDALDKSLELGPQWKNVFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX02</accession>
    <name>A0A6A6NX02_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_364524</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX02"/>
    <dbReference type="OrthoDB" id="10263597at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="8">
        <location>
            <begin position="100"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="7">
        <location>
            <begin position="460"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="45"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="319"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="662" mass="74237" checksum="CCC1CCAFCE8E427F" modified="2020-06-17" version="1">MSRPAVKRRRVSPPAFDDAWSVEQDYEKLPRKHKQEKTANRLPIKTVEGWIEQPEAEQVTGEASDSFLDSDVEDKPQEPLLERKSRLTTKAPPRQQILAAKEELARLASHINEDPEEHAGSLRKLARVTADNAPNNATVKKLELAARMAVFKDVIPGYRIRPLEDDDAQGKLSKEVRKQRIFEQALIGSYKEYVEELAKHAKGGRKPDNPGLVSVAIACACGLLEAVPHFNFRGEVLKILVGKLSSRRVDDDFNKCLDALETLFREDEDGYSSFEAVQMLTKMMRARDYAVHESVLNTFLQLRLLSEFHYKASHDGVERPSKGWRGRKKGTEKSGKMLKEKREFRTKRQRKDMREQKVLEKAMDEADAAVGHEERERLQAEMLKLVFATYFRILKARTPGLMGAVLEGLAKYAHLINQDFFGDILEALKDLINSAEARSGASNAEEDGADVRPCNVTRESLLCVITAFALLQGQDASAAALSLHLDLSFFIAHLYRNLLPISLNADIERSAKSLHLPDPDAADDRDSSRANSVNVQTTVVLLLRSLSSALLPRIALRAVPPVRLAAFTKQLATVALQLPEKSCVAVLDLLMRVIHTHGGSKNLGALWFTEERKGDGMFDATRAEYEGSNPFATTVWEGEILRRHYAPEVREAASLSRRYNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX94</accession>
    <name>A0A6A6NX94_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_422514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1749473at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="671"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="867"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="908"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="947"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1058"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1209"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1319"/>
            <end position="1329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1335" mass="137429" checksum="3AC9B211CD3973A2" modified="2020-06-17" version="1">MASPDGGGDGGGDGGGGGGASRRNYKNLPPIQTSFGDALASQQQRWRRSRPVLSPAQPKLQPTAAGRTSSSASPVRGSGSLLQPPKPNAKVEHRQSKMSLFSLFSRPKVERARGFHEPGLGATAPSPVRQSAASPQRPPTSPLAPSPVVRVFVPPKEQQQQQQQQQQQQRSSASQQPGHAEQRHLQPPQLPAPSKLLRSQKSSSIVKRSRSTTNWDPPPLFQAYPQAIKCGTLHASVVPAEQIMSRASHHHHHHGSSLHRRQYSLLQERIESTLDLAPPGTRQESLTSASEEASSFSAAPSSGAVGAGGSGLSGSGAPASPPPPPGPRKLERGSRKEHRRMSSLSASGALASPPPTGAPAPELTEKIFVLVTSGFVLQYAASGAFDRLPEKVLQLGRDSAAYASDLIMGRKWVLQVCHAVTEDGTVAPSQNKGFLSRLRVQSAAAKRVAASYLIVFDGAEDMDGWMVAIRKEIEALGGKKCHADVASSSNNVSAAAAAAAAAAAAAATATATATAAASSAASFEGVRLHEKPSHRYLVQRHPSRFESDRASSVGSPVESTRPATMVSAFSADGETSVRHSQFYQPSQDQQQQQQQQPASDAGSVKSASRRQSTTRQHHHHHHHHQQQHQHQHPRPPSEAASVATTVTSAEQVALNQLRESSRLSYVSTATETSASASASQSGAPTVVTSTSRDSSPEPAGHGAGVRKEGFHHHSQHESSESGASGGSSGSGSGAGNLALGGDAARLKSAYMVNAALPAEAGRRRSMQTLPTTRGGAGGVAGAAVFAGSGAGGGAGGGAGEGAGGGGGGPSNRAMETRTARLYRHSTYGTVGRPQLVDIPSPSSPRFPPSPQPPQEQRPHPHPHPHQHPQCPSASSSSASTTSSSSAAAPGRRRRSSAFKPAQQGGPTPSRSSPSLLDSAAAADCQTPSRSVSAPLVRAAASPPPASEAPSPAAAVPRPLSTIGALPGTAAGGVRGASTATAAGRPQPQQKSRPVSTAGGGPGWGAAGRPPVYSRPLPVRPSPAEPSIPKRHSSLFPPQAGASAAAPSWQTGANYNNCHPSSHSSSATATAPSTSPSSTNTTASSSSATGPGSASTRASSAANSPALHHSLLASPFPCSPPPHQELPPPPPPPPPKPLRRPSSMLIRSDPAPFLSGRGGAARPHILTQSRSWAALNSAAKPPAPPDPDPAPLPPLPPLGNAFAAPGPPLHHLHHHHHHHHHHQQPPGSSPPRRASAAPLVPPEPAPDEPRQQTRPTTPSLADARARLQRLQDREHELLLRRRPATAARVQARRSLPVMGLPPPPPPPNVPLPPPPPATAGGAGAGAGVAWGRGVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXE0</accession>
    <name>A0A6A6NXE0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_364583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXE0"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="2">
        <location>
            <begin position="11"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="433" mass="47187" checksum="B38A664F0E31C0AC" modified="2020-06-17" version="1">MDTSTRQYELVLFGATGYTGKLCAEHIAKNLPTDLKWAIAGRNEKKLSEIAKELKSINSDRIQPEIEIAELNDTDLDALAKKTRVLLTTVGPYHKYGEHAFKACATNGTHYIDCTGEVPWLKDMIEKYEETAKSNGAILQLYFNAKMIPQCGIDSAPPDLLTYLLGTYLLQTHSAPLTTSTITAHRMKTAPSGGTLTTILTLTDTYPLRALRASTRPFALSPVQPASRAPRASAPLLERVLGVRRSADLGVLTAHPGARGDAAIVYRSWGLLDAGAYYAPRFAFSEWTTARGVLAGAAWHWGLLAGTLALALPPVRAVLRRLVAQPGQGPAREAAEREEMEYRGVGEGMRNEGEQVRKARATWRFKGGMYLLTGILMAEAAMVITRGKGTRAHEAGGGILTPAMLGEAFAERIRKVGIEVEVGDRFVEERARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXH9</accession>
    <name>A0A6A6NXH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDY21DRAFT_288338</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the C-terminal section; belongs to the chitin synthase family. Class V subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the N-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030436">
        <property type="term" value="P:asexual sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030448">
        <property type="term" value="P:hyphal growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000337">
        <property type="entry name" value="Chitin synthase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000012">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.530:FF:000017">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000019">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000055">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 18" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 18" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="951"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="990"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1262"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1657"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1684"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1712"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="22">
        <location>
            <begin position="1"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="21">
        <location>
            <begin position="1014"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="23">
        <location>
            <begin position="1876"/>
            <end position="1931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="608"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="110"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF2456162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1934" mass="212605" checksum="DA62B8669F7EB360" modified="2020-06-17" version="1">MAQESSLGSNAGAGSGHQPQYAQASLPSLPQHLQSDTHLTAHLASRFHAHLPTAQLSSHGYVALNTYTSSTKGPNGVEEGSAMAAARDVAARAWTRLGHRSENQAVVFMGESGSGKTTIRSHLLSSLLSFSSTPLSNKLSYAAFVFDSLTTTKSVTTPTASKSGLFFELQYDTTASTMPTLVGGKVLDHRLERSRVASVPTGERNFHILYYLLAGTSAPEKTHLGLDSPGAVVNEPGARSSLTAGGQKRWRYLGHASQLRVGINDHEGFQHFKTALRKLEFPRSDIAEICQVLAAVLHVGQLDFAKTQATTPAADESGGYSHEGGQDVTTVRNKDVLGIVAAFLGVGTQDLEVSLGHKSKTIHRERVTVMLDPRGARANADELARTLYALLVAYVIEQVNQRICAPEDAIANTVSIVDFPGFVPVSATGSVVDQLLNNSAQESLYNFCLQTFFERQADMLDTEDVSVPATSYFDNSEATRALLKPGNGVLAILDDQMRRGKTDAQFVEALRKRFEGKNGSIAISAATTTLPGTNFKTVNEHPTFTISHFAGEVEYSAEGLLEENGEVISGDLLNLIGSTRSDFIRELFGQEALNRVHHPKEKTAIMQASVSSKPMRMPSMARRKTERAGRSLLARPSVRGGGLGGGADTDDDGTTTRSGDEGNRSVSRNRRAGHKDAGSGQGAAAQFLSSLHAITKSLGAPNTNAYFFFCLKPNDRRIANQFDSKCVRTQMQTFGLAEVSQRLRLADFSVFLPFSEFLGLAEAGAAGADSAAAAVVGSEREKADLVVDERRWPDNEARVGATGVFLSERAWFDVADVPPDGVLGQAAGGRVGGYPRGAAAAAADSDEFLSPEAARGGGPYSESRLRLMGAGAGSNGNSQQSSPGAFYHDDKAGGYFGSRELDAKSDAGASAFRDGDMFRNLETRAQMAEKGNELKMETVDESPVSGSRKRWLFLVWLLTFYVPDFLVRLVGKMPRKDIRIAWREKFAINLLIWLSCAFVVFFMIGMPELICPTQHVYSQSELSSYDGKDGNSGYVAIRGIVYDLDAFVPAHYPAIVPADDLMDYAGRDATNLFPVQVSALCNGKDGSIDPAVQLSYKNNNYTDSDTLVSSTDTNAKYHDFRWATNDSRPDWWYEQQMYLKANYMKGRIGYSPQYLKTLADKQNYIAIINERVYDFTTYIPGGRAPQYPDGTDPPDEMPDSNFMDSSVVDLFQQRSGEDVTKYWNALNMSPELRANMQGCLDFLFYVGDVDTRNSAQCLFAKYILLAISILLVSVIGFKFLAALQFGKKNMPENLDKFVICTVPAYTEDEESLRRAIDSAARMRYDDKRKLLVIICDGMIIGQGNDRPTPRIVLDILGVSETVDPEPLSFESLGEGMKQHNMGKVYSGLYEVQGHIVPFLVVVKVGKPSEVTRPGNRGKRDSQMILMRFLNRVHYNLPMTPLELEMHHQIRNIIGVNPTFYEFCLQIDADTVVAPDSATRMVAAFLHDTRLIGVCGETALTNAKSSVTTMIQVYEYYISHNLTKAFESLFGSVTCLPGCFSMYRIRAAETGKPLFVSKEVVDAYAEIRVDTLHMKNLLHLGEDRYLTTLLLKFHSKYKTKYIFRAHAWTIAPDSWKVFMSQRRRWINSTVHNLIELIPLQQLCGFCCFSMRFVVFLDLLSTVVQPVIVGYIVYLIVLLARSSDVVPITAFILLGAIYGLQAVIFILRRKWEMIGWMIIYIIATPVFACGLPLYAFWHMDDFSWGNTRVVTGEKGQKIVVSDEGKFDPNSIPRKKWEEYQAELWDAQTQRDVDTRSEVSGFSYATKSFAGLGAAPGLAPGGPPSEYGFPPSRPMSQLDLPRYGSRLSLAPSGYGGYNNNNNNSHGGSEMEMADMMQGLPSDDALLAEIREILKTADLMTVTKKSIKNELERRFGVALDVKRQYIGSATEAILSGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXK4</accession>
    <name>A0A6A6NXK4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Probable electron transfer flavoprotein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_347120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </cofactor>
        <text evidence="7">Binds 1 AMP per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXK4"/>
    <dbReference type="OrthoDB" id="276685at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000011">
        <property type="entry name" value="Electron transfer flavoprotein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294:SF8">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00070315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="28480" checksum="B5B0642D3E1EC70F" modified="2020-06-17" version="1">MPPLRILVPVKRVIDYAVRPRVNKTQTAVESAGVKHSMNPFDELAIEEAVRLRERSKTTGVAVEDILVWTAGPAKSSDVLRTALAMGADRAIHVAHEASANSATQLEPLAVAKMLSKVAKDEGANLMLLGKQSIDDDACQTGQMVAALLGWSQATQAAKVEVDKDGHCQVVREVDGGVETLRAKLPMVVTTDLRLNEPRYASLPNIMKAKKKPLIRVAAEDMGIDLRQRIRTMKVTEPPPRKGGTKVEDVDSLVGKLKELGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXQ7</accession>
    <name>A0A6A6NXQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_53388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXQ7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17755" checksum="7B72634AA4317E0A" modified="2020-06-17" version="1">MKRAVPVPETRPHAAPDRWFAHWSRERGRSACPPAFQTRPSPITGSCAPALLLRMAGRSCGALSPRRRTPNSMPSTTASSYWTARRTFLSSPETRATRETRSCDRLTGPYCPRLSFVLPKGSIFVALYPLSREVASWRSYHRRGAATYRGLLGLEHLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYV7</accession>
    <name>A0A6A6NYV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fcf2 pre-rRNA processing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_346043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYV7"/>
    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="102"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="226" mass="26110" checksum="1F7762F0812C331F" modified="2020-06-17" version="1">MRGKWTLDPGELEELRRLYSDAAESVRQDITTSSRGELAPLASSAVMGAPPPLPPLIRRYLDMDVSRRATKRTQEPKTSSDLRLRKVEDPVAAKKRRQREKHATAGPDWFNLPRTEQTEEAKRDFQLLKMRSVLDPHRHYKKESAKAEMPKYSQRGTLIEGPAEYYTARIPNKERKRTFVEEVLAKEAESGKFKEKFEALQATKRSGKKEHYKALRAKRASNFKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYV8</accession>
    <name>A0A6A6NYV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_287141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYV8"/>
    <dbReference type="OrthoDB" id="431691at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="50" mass="6200" checksum="9A9A4D75C2B4EEA5" modified="2020-06-17" version="1" fragment="single">QIRLYGRGRTFNPSHRVRKRRHGFLARARTKAGRKILNRRKTRRARYWSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ39</accession>
    <name>A0A6A6NZ39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_53124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ39"/>
    <dbReference type="OrthoDB" id="3598904at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7667" checksum="351FA5043C04A36B" modified="2020-06-17" version="1">MRKPSEAPAAASTAPEPMLQDRRGSVFHRTKTGCSTCRERKVKCDEKRPFCTQCLRRKHHCPFGYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZA4</accession>
    <name>A0A6A6NZA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_364467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZA4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025499031" evidence="2">
        <location>
            <begin position="24"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="545" mass="57564" checksum="EDA664E4C6F7A93A" modified="2020-06-17" version="1">MRGLHLIPALGLFLSGLILSCHGAESATLAAASNENGDNDNKYGGECPLDGPVFGIELTLDSLASSVVLPNGTRTGLATVEGDDDYRALMRDWLAIAEGFEKEKKVPYELINSYDSILASTSPAYKSYLTAVTAPPPPPDAPIPVSPPTPPYPDPLSLDAWTATLTRALVNLTTLTLTNLTTHYPSLVPRPPAVEAPSYFDRLYGHLPVASDDPHARTPFYLSSTAAFPPLAHNFFALFALPTWLFTPAPPSPHVPYYSTPHDEHPHSPTPWQHPLIARVLTAAGRAGWRLHPARAPARSAETLRDVARAHAVPAGAAAVAAARANVLRGGLKKLGARVLVVEMDEGGLGLYAARVLPASAKPGTAARPGGGDDPLLAAVEGVAGVGAPFALDTARGGAALKATEKPAKPRFWLRASDAINAFVDAVEAADRSVSAPSGGGLVGGTAAAPQDDAPWRVVFKGDTLGRGTRDTLENALQKRMGVNGARSKDWIARAPKAGFVGSVGAGVVGRRWVEEECAVREAVEEEREGVRREERENTREKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZI8</accession>
    <name>A0A6A6NZI8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cofilin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Actin-depolymerizing factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_34203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZI8"/>
    <dbReference type="OrthoDB" id="10249245at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="17082" checksum="A27167938248E7AB" modified="2020-06-17" version="1">MAQSGVSVSPECISAFNELKLGKDIKYIIYKISDDWKEIVVEETSKEDDWSAFREKLLNAKSKDRRGKEGIGGRYAVYDVEYDLEGGEGRRNKITFISWSPDDAPQYPRMMYSSSKEALKRALNGLAADIQANDADDIEFDNIISRVSKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P066</accession>
    <name>A0A6A6P066_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_287032</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P066"/>
    <dbReference type="OrthoDB" id="238681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000005">
        <property type="entry name" value="N-glycosylase/DNA lyase OGG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="12">
        <location>
            <begin position="141"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="404" mass="45783" checksum="B2137FC819929185" modified="2020-06-17" version="1">MTTARTSEWRKLPVSLTELCIDTTLRCGQSFRWRRSDDGIWSCALRGRILSLRQDAQHLYYRSVCPNPATLPTPPATPSVTDEDDDTLELIEHYFNLKPNLGQLYDEWATADLNFRRKAPKFTGVRILKQDAWEALVGFICSSNNNIARISQMVEKLCLNYGPYVGTIDSKPYHDFPSPSTLVGPKVEEHLRKLGFGYRAKYLHQTAKLVAQERGEGWLEDLRNPESSLRPQPNQSAGEMVEGGREGYRKAHEELLNLQGVGPKVADCVCLMGLGWGEAVPVDTHVWQIAQRDYKFGKGKHSSLTKATYDGVANKFRALWGKEAGWAHSVLFTADLKVFAERLVAKKEEHIVEVKVEDEGVTTVVATRETKEKLVKRGFEEAEYPSVKIEETTARRTSKRRKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0T8</accession>
    <name>A0A6A6P0T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_385729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0T8"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14016">
        <property type="entry name" value="STKc_CK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="16"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="298" mass="34497" checksum="7ED750A94E1C50FF" modified="2020-06-17" version="1">MSESEKELDIRVNDQYRLLKRLGGGSYGVVYEGADIQTSRHVALKLEHVRSRHSERLQNENGHECDYEVMVFELLGPNLEDLFNYCGRRFSLRTVLLLADQLIRRFQYTHSKGFLHRDVKPENLLMGCGTRGNIVYITDMGLAEESTDAAAALNDRQREGPVIGTARYASINAHRGVEQSPADDMEALGYVFVYFLQQGNLPWMGLRGKSQSEKESAILRKKQSTSPEELCEGLPDEFVEYFNHIKTSRDNNRGVDYKYLLRLFRSLFQRHGFEYDNVYDWTVLKYMEHLEKHNLIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P197</accession>
    <name>A0A6A6P197_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_321131</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Transcription factor that is part of a SLN1-YPD1-SKN7 two-component regulatory system, which controls gene expression in response to changes in the osmolarity of the extracellular environment. Under low osmotic conditions, phosphorylated and activated by the phosphorelay intermediate protein YPD1. Also activated in response to oxidative stress, independent on the two-component regulatory system. Regulates heat shock genes in response to oxidative stress and genes involved in cell wall integrity in response to osmotic changes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the SKN7 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P197"/>
    <dbReference type="OrthoDB" id="424572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000212">
        <property type="entry name" value="Stress response regulator/HFS transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000380">
        <property type="entry name" value="Transcription factor SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014402">
        <property type="entry name" value="Sig_transdc_resp-reg_Skn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002595">
        <property type="entry name" value="RR_SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 12 17" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="16">
        <location>
            <begin position="391"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="277"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="341"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="529"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="633"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="361"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="533"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="555"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="673"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="13">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00057149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR002595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2457669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="702" mass="74381" checksum="2BF21FF0C79FD714" modified="2020-06-17" version="1">MDSQGQQGGGGGGGGGAANSSSDFVRKLYKMLENPTDENVVRWGNVGDSFVVLENEKFTKHILPKHFKHSNFASFVRQLNKYDFHKVRHNNEEGGQSQYGPGAWEFKHPDFKMNNADALDNIRRKAPAPRKPNASQEDMVIPSAQMDLLNTQLAATQQQLQALQSQHQELSIHHSMLLQELIGLQKTVVNHEHVMQNVMSFLHSLDAQRRRDSRMVNPFGQQNGATAPPPPPEVPPLEEDVPASPLQHASKLLSETNADVMLNPRNLEHMNEISMRMNGTYTSPPPDIAMRNGVRQSSGGPPPSAGSSANSMRLGELDNVVYPVGQNNGIDPMYAEHINNIPYPMPAKPQEDPRFAGGVDGAQPGQQPGQPGQPQRKKSAQVDPGWVRQPHILLVEDDQTCRRIGGKFLLAFSCAIEMALDGLEAVQKMNGPQKYDLVLMDIIMPNLDGVSACHLIRQFDNTPIVAMTSNIRSDDISMYFQHGMNDVLPKPFTKEGLLQMLEKHLSHLKKPMLGGPAAMDASGAIVPVHQQQPGPASARPTSARAPPAMKDDDSPPAARSPATSATTTTTTMTNWNSPGGQLGAGVSPVAQAVAADDPSAAAAAAAMQMPSPAAAAAAAAQAQAQAQAQAQAQQQQARLGGGGAAGHRRQISDISGGEEGVGQGGAKRAAQGQGQGQGAGGGGGGGGGGGGGLYGGGMMGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1B4</accession>
    <name>A0A6A6P1B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquinone biosynthesis protein coq-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_304412</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1B4"/>
    <dbReference type="OrthoDB" id="201153at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="6">
        <location>
            <begin position="367"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="716" mass="79511" checksum="B0132A98017E40CE" modified="2020-06-17" version="1">MSGRRLIDAAKVLRASQTIAKQHVALRSQQLDVFTKTSSLARAAKSQADRVTVTARAAIALAERLRETAPPPPPGFSSDHSKHEQTGDKAKEKAFEDRQDVSRERSGADFGTTQELKGSSQEAQQSTAAEEPAIERGPSPLAEAGTENIVDERERAKDGTRGPTDPEKYAPRHDKLAEATLQEEEMDVPEGANLDVFRTRRVSRMLRDQGFRQNPTPNPYIPKSEEPARSKVTSAAENVAEETAPQVDTTPEVVAAPQVDDAQVRTHENAPTPFQLRQSRVPSSRVGRIWQYGGLATSMAWGMMGEGLRRVTGSGSDAGSLLLSASNTERLVAKLSKMRGAALKLGQMMSFQDVKMLPTPIHEVLRRVQDSADYMPPSQRDSVLAKNLGCDWRDLFSEFEEVPIAAASIGQVHRAILRSDDSQVAVKVQYPGVARSIDSDLNNLSLLLTASRLLPKGLFLDRTIANARTELAWECDYVREAEGARRFKEFLADETDTFTVPAIIPEASAREVLTAEYMAGTAVTKIPHLTQEQRDWIGTQILRLCLREITEFHFMQSDPNWTNFLYNAQTEKLELLDFGASREYSDDFIDRYICVLEAASRGDRKTVRDISLELGYLTGHESTMMLDAHVDSVLTLAEPFCVGAPEVYDFRDQTITDRVRGLIPTMIKERLAPPPEETYSLHRKLSGAFLLCANLGSRVRCKELFEKAILRLDVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1B9</accession>
    <name>A0A6A6P1B9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 74</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_344312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">Golgi stack membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1B9"/>
    <dbReference type="OrthoDB" id="2189106at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048194">
        <property type="term" value="P:Golgi vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3630.10:FF:000002">
        <property type="entry name" value="Vacuolar sorting-associated 74 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="364" mass="40944" checksum="3A4B012C2929845C" modified="2020-06-17" version="1">MATSSSGLTRRRGGGINATAENDESSRVGSPVPKRNDDSRAPETSYENSENGHKIAFDPRDISESAERSKQPKLTLMEEILLMGLKDKQGYLSFWNDNISYALRGCIVIELAFRGRISMQKDASRRRFPLADRVVEVIDDTLTGEVLLDEALKMMKSSEKMSVSSWIDLMSGETWNLMKIGYQLKQVRERLAKGLVDKGILRTEKRNFLLFDMATHPVVDGGAKDEIRRRVRNVLTNRTVVLPPSQFLPEDMEFRYLRTVAMVCAAYAANVLENALTTLGMDARERAFAQVDELLAEYSQWPFARRTGGSGGVGANLGQAIQDEVNNAKDKELQLEASFHFIFFQSTNCVTIPTRTMYLLRPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1F7</accession>
    <name>A0A6A6P1F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_371748</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)</text>
            <dbReference type="Rhea" id="RHEA:67920"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 19">Preautophagosomal structure membrane</location>
            <topology evidence="3 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the ATG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1F7"/>
    <dbReference type="OrthoDB" id="2020634at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0072">Autophagy</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 19" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="690"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="750"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="846"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="760"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="851"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="868"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="924"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="949"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="990"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2457572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1032" mass="115086" checksum="CAFD05697D26AFF2" modified="2020-06-17" version="1">MASNILSRLLPSADDDRSVYERLQQRDQPPLRRRRASPGSGGEQRYHDHRSDSSASPFHDDDDEHRGDPLDEENLAARFQDQDLDHLLADAAQSHITTESTAFLPHSDSPGRQRRDMSPSLLRGSRGPGAPRDAQQQRPRWMRGRAAPAIPHPDDEDEDVPASLMLEGDTAQRHGGPSNRRVPGRIVDDLPPPVPGPATQNTRAQWDATRAQQQLHNDEQVGGPSRLGQGGGARGGDRRRGNSYMMADPKERAKWKWANVQDLDRFLHEVYEYFAGHGIWSITLRRLLNLLKSAFVIGFSTFLTKCIDYKEIPKSQRMEEILVPQCIKRMSSFWNITLWIFVFFWIYKVFQYTNDLPRLWGMHNFYHYLLDIPDRDIQSVSWQDVVEKLMILRDTNPVTAQNVSAENRRFLGTQSKQRMDAHDIANRLMRQENYMIALFNKDILDLRVPYLGNRQFFSQTMEWHLKLCIMDFVFDEHGHVRPNIVDSHQRRHMIESLRRRISQTAVLSILCAPFAVVYYSLWGFFEYFTEYHREPSRLGLRSFTPLAEWKFRDFNELYHLFERRRNMAYPYASRYLDQFPKDKMNQTYRFVAFITGALAAVLGLATLFDPELFLGFEITPNRTAIFYLGILTAIFQAARSAVPDEQLVLDPEFALNNVIDLTHYCPASWQGRLRSDEVRREFAALYQLKVVIFFEELLSMVLTPIVIAFTLPNCAERIIDFFREFTVHVDGLGHVCSFAVFNFKRGPENNTAAARPAPSGPGGAGGGSGNGGAGGATGGQPATGGLRDDYFAANDNKMMASYLSFLDNYSGQPGGGGRAGHLPPMYGRHYLNHQRRTFFNPPPPFPGLGPGTAAAAAAAGASPPMQQHHAQGQPPTALAGSSTPRFGPHATGPATAASPLHSTLLDPHHQPSPPLGAGGARTSPRQGPAGARFRGARPGALDEVAEAPADQVEAGGVQQQQPGGAATTSRMIEEDSSLGDSWRVTRAGQMEDEEDGEAEGEGGEASRGAPGVLGLLKQFQRVHTEGKGVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1L5</accession>
    <name>A0A6A6P1L5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1L5"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="434" mass="46326" checksum="03062FD9EA349184" modified="2020-06-17" version="1" fragment="single">MLLTLPNPTKTELDHKPLHEYSPPVQSPAIRFSPKVNGGPVGSLPARASTMGTPHRGLPPPAAMTLPDPSRGAPPPPPPGPGPGMPPPPAQWQGAEESMRNWLVAKKEEERRKQEEERTRQESLRLEQRKIEQSMLRESMQGGVPPQLVPMIFAGIGGGNLPSISVDWLQQYMTQLQSAQQQQQAAIAQPQMSPELRRDQRLISQGPSTFGATVPASHQAPPPPGPGIPAQQPPSGGFQTTFQATGMSPSSGGRGQTAVQAQGPTSAPRPPPHSSLPKLTTNEMQIQQPPSIPSAIHPLHQTQTAQEQQSSPSIYFHHWVPPTSQEKGSSGNQPATPSGKQTTSRRGTLSHVSDAEYSSSPKKRKAQGSHQAAPAPSSTPQYTSPSFSQMSSSSTSTPARRGHARTRSDASTRGQEAPARPSSRQGNLPGQAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1T1</accession>
    <name>A0A6A6P1T1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_16320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1T1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025570600" evidence="1">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="10560" checksum="0A2E791BA36EF532" modified="2020-06-17" version="1">MRTKYLVAIITLSCHGLVFQPVSSLSSRKGRLLQTGGERASLVSGMLNLESYWLGEMKKYFCTIRDMLSFFPSRVHVVCILGPYDLTDGVEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1U1</accession>
    <name>A0A6A6P1U1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_378990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1U1"/>
    <dbReference type="OrthoDB" id="5341924at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1143"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1183" mass="129776" checksum="21ADD0AA13430B9E" modified="2020-06-17" version="1">MHSNLSSILRRTFNLHSKGFSASAPSTVSQFLVPSVAVAPRAPSRPLSRCHPRQLQRTDNASARQEKPVLGPRQSDERRPSLFEEIHTNPESSLILKQPDDEHRDASDWARMLDSLLPTEYAQRGSAADGGGDTGTEPKRPPEGPELAKRINGVLLRAQRCDINLLEYMALVEGRWEAVKWIVSVVVTYDSARQAVEARRRPYRVVRNNIRRLDEATLRAIWAEASAATAAGTEMKLPLEDLTMAALTDLPEHGSDLFKGGVGVIWQGLGYILVHTAQQSSKEEANKILRHVLAMIALLHHSGVVPEAVYKYGENRDRSAFQQPPILALLNPAIMGALAEAELTAYPEDKDDQAAESATKRKSILGRFNKYFTTAGPTRRDFDLEPELWLELVLWSCLHGPWTRNGGQILRRIALQLGPSSTDRPWKLISWQSFMSILSPRRRSAKPDLNLYPSFFSWKALQLALPTPNAHFSAAQGERVLIPRSLSAELAAAYVRGLLSTGLTVGVSRRGASFDEVLDVVEGVRYMLLREGLSGLGGGLGWEEVVAGLVDGLGLDLEEDPRAGLRVLRLAVGFDREVLTSEGNGGGDGWSSGAGAEPKAVVLDLHHRVLAAFIRKRDFEGAVDAAKQLRVHMEESETRLIELRLRLHKEQEGAHPSSLRSETNYDHLSSFSIPPPAPILASFLDLATDARAFSITNCLLLEAPSPSQPPFIPPSSYSSPTLGPSLIRFAGHAGLHPLLMAAFKAQLARRQGASFRSWDNDALATFIVAQIELRNWDAAANGIASAWQRGGAGGERKGWAPRVLAALARQMLSVSTGGGTEAESERGDWKQLREAVRTRGPERCMPLVPHSAALWAELARRLADEMRVAAAAASPPSHSRAGRQRRDDGPLPALVALLASLDPLLARFVTDAFPLERTHWRHRRRCFRSRLDAGLFNSLLEAAVELKGWREGVELWERWCLDVLEEGRGRVRAGRHGGVSGLLSFLGKARVRGVYVGGGRKEGERKGGVEVVVRLWGPKDGGAGEGVETREGGRELGAGTSEIEYTVSLAGSRVKPDQRSMLIILHAAARELRALSEQVGGEGASDGQGWGVVMRRAKEVATWARRRMRALGFEEERIERELGGLVPERSRDSDIMWKRLELHRTEGDDNGQGSTREEKIGGTAQSSGRDARFGLGVEESLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2R8</accession>
    <name>A0A6A6P2R8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_363224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2R8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="285" mass="31666" checksum="37CAAA70A3016AC5" modified="2020-06-17" version="1">MSDFMLTITHSSHFRSASTKAKEHYSYFEFVSAKIQQYFGYFKLGLSGRISAYFARSAAGYECALDSMRAKGFPGPNTPWEELLTLLESCRYRIHLGTGAGSASITRQIVPTISGILQLLRYKGYPMVVKGKPYVEALFATDYNREVGSLGGGRGLTDDDEATRSMAVHRYLSHITYSTHFSKVLQYTRFLSKDVDKMVERTDYGFRAFFRKTAPNPTIPVYDSCTAVTKYIASGSPKLQLLCGTTNSKDYDGGTLAEGNPGPGPGGKFLYAEKHEVDNMVDFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2X8</accession>
    <name>A0A6A6P2X8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_284555</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2X8"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000061">
        <property type="entry name" value="Metalloreductase transmembrane component, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF23">
        <property type="entry name" value="FERRIC-CHELATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="380"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="627"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2458118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="820" mass="93230" checksum="EB623FC36D4E27D2" modified="2020-06-17" version="1">MPARRAAEALAQHGPAGELIGRALAEEASVLVARINPPYNDSSPGQIEAFTRDPWDQSGKYALGVVYFCVILLVFGSFLRFYHLFTDKIRTALYQEEVVKSSATSSPDTDYELSVLDTDKSTHKFFPRDGPLPPPPKTQSSVSSVGPINNAVALFRFVFYRPIPSIQIDKVYRPIVFPSLAIVAIMSTLLVFTLLYTLVPQPWYWDSMRYGAPPVAIRSGMLAIALLPFIVALSMKANFITLLTGIGHERLNVLHRWGAYTQLVLSIAHMIPFYIPAIWDKEGLRIYKSYFNNNGDFYVYGTGIAALVPLCFLIVHSLPVLRRWSYETFKVLHRPVAILYIAMLFWHCHNYLTSWHYLYATIAIFVSGWVLRLFFYFNFTNPWRQESFAVGDQAFINIMPENAVKITIPTKVRWRPGQYVYLRMPGISLLENHPFTIASLCSEDFPSLAGEEYRDMTVVFRPFAGWTQKVLDKTVEKGEGHPWQAWIDGPYGGMQRRIEAFDHVVLIAGGSGITAIVSQLLDLIKRMRDGKAVTKHVQVIWAVKRPETMEWFKEELRICRENAPPDTVQCQFYITGAKRLTKTADDPNQGSTRPHSLHVHDKVNHFLTDLADKRLSNQSAKRNSALIRDEAAGDAEKEKELRRENEDAITALPQAHIMPARRPSRSHLGVPEVQAPQPIRSIWERRQEERHTGRDMSHDVYTAAEANTGAFAPTAQQDAQSFDFGFPSTPTEFQKNLMRFAFLPAAVKKRDGWSTEYGRPDISYMLRQFSENFGRRTCVFVCGPPSMRISVCKTVAQLQLDVLRDSDKDEIFLHTENYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Y7</accession>
    <name>A0A6A6P4Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_200010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Y7"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034757">
        <property type="term" value="P:negative regulation of iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000039">
        <property type="entry name" value="Siderophore transcription factor SreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="12">
        <location>
            <begin position="151"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="12">
        <location>
            <begin position="360"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="105"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="197"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="307"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="412"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="461"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="618" mass="63798" checksum="82EEE201E4C371E9" modified="2020-06-17" version="1">MSAASASRPSPAPAALNVPPHHRLTREPSKEDLEMAANLNLLTQAGHAVRDGDTATSANGTSGPQSREKTTAQTNELVGKFESGKGRSGAAEVTEYHSLDDSMRVHNSAEHSPSPGLSTTTAVQSENEQGSPLQLEQQPQQSARPPNQHATMSGQVCSNCGTTRTPLWRRSPTGATICNACGLYYKARKQSRPTNLKRNIHTHAPPPFSVGSSPLSLSANTGGGGASPGPGDHRSVSPSSNMAGLNNSGPRATYVPADTLQAGTCPGGGRCNGTGGQQACSGCPAYNNRVAKTAQFALAQAAAANEGITSDGSSGPDSQGTGTVGVSIGEVGPQSSADQSASQNIQGSAGGIGSPLVPACQNCGTTITPLWRRDESGHTICNACGLYYKLHGVHRPVAMKKQEIKRRKRVVPAMQDQISASPSSATDSVPSHSTNLTASGTVGTAPVAQSVEDQLRTHAAAGAISGSSSTTRAHGRLDQPATPLDPALQQASTSNGEVRTSDGYHRLAPPPADFTFYHAEATTPSRKRSLSVAEGDGHGEAGSQQQVSGEEGGGNADPSIDPVLTDPGSTQDERQADGTAVDADGGKSRRAELLREARMLRESLAAVENEISRLEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5A6</accession>
    <name>A0A6A6P5A6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_200671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5A6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="31534" checksum="4CD5F31675919F27" modified="2020-06-17" version="1">MRSTAKSRSRCPTAVFWKPMIMTPSTPAAHGSARHRPWATPILLTARNVPANHRAARTRRMRRYKALQVGSRVVKKLSFTKAAPPSSTATRRQSSLHRAAKNLRPRCTCRYVCFRAALYLPSYYRRHHFGTVAAGRCTDRVMLPETEGLARGALACTSKPNIPSSSARMLLLPSLSLHEEHPRSQRPIPTWKTVYRICSILDGWLITMQPLRIAPLSTLRSQPPHAQGKRSRSPVLAGSCPCRNTHSRKPRVLWPGQFPPGDHRNNMPFPGRAKHKLGHGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5V3</accession>
    <name>A0A6A6P5V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_257622</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5V3"/>
    <dbReference type="OrthoDB" id="1535081at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF11">
        <property type="entry name" value="O-METHYLTRANSFERASE (AFU_ORTHOLOGUE AFUA_2G17820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="6">
        <location>
            <begin position="59"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="178"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005739-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="377" mass="41475" checksum="ACE63E87E24AE965" modified="2020-06-17" version="1" fragment="single">MDTSDLTKSIAAAADATPQNMTDEERMKLLAACNKLSRSLEGPLDATLRITSGPFEAICLRLAVDMKLFDAIVTAAGSATNEQLGNATGTDPLFVRRITRMLAAMGILKEVARNTYAMTPLAGAYSSKSPLSSAIVHLTSHMPAIARLPDYFAERGYVNPTDAYDSPWQFGLQTQKHYFDWLADHPRIQEAFNVTMSAARQISGKEWFDVYPVEERLLPKASSASDVLIVDVGGGIGHQLLGLKRKFPSLTGRLVVEDLPGVVEPASQSLAKSGIEALGHDFLTEQPIKGAKAYYLRTVLHDWPDKQAKVILDHLHAAMDNDSTLLINENMLPEMNVPHFNAVLDLRMMTGLSAQERTEAEFQQLLESAGFEVKKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P678</accession>
    <name>A0A6A6P678_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_275419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P678"/>
    <dbReference type="OrthoDB" id="5342685at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF30">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="105"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="748" mass="75961" checksum="773388BF03D14BD1" modified="2020-06-17" version="1" fragment="single">RLLPGLEESEGALYEIGVADDGTFVGLAQDEMDESLTNLRAMAASLGCVVEVTRMVPVGECECAERAVSTTGLSHAANNGGRLAGDTCTTAGCERAAGAVDQLRVSLTGATMSGKTSLLGSLSTATLDNGRGKSRLSLLKHRHEIASGMTSSVTQELIGYQTRNGPHSSRYTTASRAATTVVSVVNYASPHVSSWTDIHAAVQCEDRAQSQAQDSRLVLLSDSAGHPRFRRTTVRGLVGWAPHWTLLCVSADEAGGGPREMGHGGGSAGAASGSPGSSGVASGGVSLADVHLSRAHLELCLDLELPLVVAITKLDLASKSGLRATLSSLLSALKAAGRKPVILPDTKHAGAAGAPPLTEADLLEVSGRDLADAGKVVRELAANPLGTVPIVLTSAVEGSGMGKLHALLKELPVPAAPGVPPAVVGDDTHEDEDGSPPVPLFHVEEVYSAHAVSSAQQPTILAGHVRYGSISVGDTLLLGPFPAADSSLYAAGGISTGKRDASEMQAQVHDALPDRFPVPTSREFPGALIRNLRLPVTALRADQVGTLGVVPVPVPLHGTTAVAAGDGEALAKVRKGMVLSGNNAAGKPPRGRRAFVARFEAPETGAGGAGPRGAGGGGGVRSMTVGSGVVVYVASVRASAKVVALAAELREAMAPVEDDDDTLGFGFEAEEAAGSESGSFEDDGEADGQPDSGATLASFQFLAAREFVEVGARVLVLPGGGPGLYVGSERGEKGVAGLEGFVGKVVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P684</accession>
    <name>A0A6A6P684_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="5">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_362220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="5"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P684"/>
    <dbReference type="OrthoDB" id="5558646at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF13">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="6">
        <location>
            <begin position="19"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="248" mass="26242" checksum="FB73AA5AB95A7F18" modified="2020-06-17" version="1">MKTSASIVFAMAAATSKAHSIFQAISVDGENQGELVGVRAPSSNFPIMDVTSKDLECNTGLIQPVSTDVVEIPAGADVGALWGHVIGGAQVPNDPDNPIAKSHHGPTMVYMAAVDDAGSAETSGLDWFKIFEDGMDEEGVWGVDRMVADDGWVMFTMPECLAAGDYIMRVEIIALHSAYDVGQAQFYNSCANVRVTGDGTNTGGETVKIPGVYSAEDPGIHVTIYDEDGNTDMDGQEYQIPGPEPMSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6K0</accession>
    <name>A0A6A6P6K0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_338705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6K0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="20410" checksum="9DB08EE1B9B7208A" modified="2020-06-17" version="1">MVVLQAPPGGQRSKERDLGSRDPDGSPHAKTTAPHLLEALGPFGGGGRSCAGALRATTARRAGRRRRAGGGLLVGCWLRLSELSEQCMCCRPGAGRTTRTEAGAAKGTAPRREGLKSSPDGDDWEKRRQVRGGNEKGKKDWDERESGRAGAGAGLALCTRAEQFHQSTLVRNCKCLLARRSICYIYLRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R6</accession>
    <name>A0A6A6P6R6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6R6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025439734" evidence="1">
        <location>
            <begin position="25"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="213" mass="23914" checksum="B6CB6694D310ABB1" modified="2020-06-17" version="1">MLPTLFLALLVLPALCLLVDPAFSEGLGKLDSRALTGLNSSTAVTEHYHFQFDSAVQHSNSPRRCGDGYTNKSCLFNNIFFDSSLVGRIIWIRESYHELRGNYELELYKPDVNRTFTRKRYHITVKYSFHSGWKATGVSFYASCGKPTTCEAPSITLPVATSKAELIVPFDQLESCRNIGHRGRNVNVTLIISANVQKQVDDDSVWAPRSQCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6U0</accession>
    <name>A0A6A6P6U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_191050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6U0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="258" mass="28062" checksum="E7F83395B3C89FB0" modified="2020-06-17" version="1">MASKLPRRALVEPRPGLLPGSGWAIACVQPLLLSSRVTSTFNCPSISFLPFSTPGRFLFYLVLLPPDFQVGFRSVWSLLYPFPPSGQSYIFFFSNGEQGLVSKNGRGGCGWKKGVAGMGGAFSRVLVVGSSVGRLGMRHERERAKFTMHDTWGFIFFNFYRFCPTSLLLLLSCLLWALLVFSMSATVSTLTNLSVVACVFFCFASFFPTLSPFAMAGTTRLPIAGLSALVQMLGVAGLTVPCSVKYWGLEGSDREAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7F2</accession>
    <name>A0A6A6P7F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_361665</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7F2"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="109"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="312" mass="33669" checksum="6D140F49B8F3476F" modified="2020-06-17" version="1">MGGKSDTKAAYFDKLKTLLEEYRSIFVVNVDNVSSQQMHEIRQSLRGEGVVLMGKNTMVRRAIKGFISENPEYERLLPHVRGNVGFVFTNADLKGTRDKILSNRVAAPARAGAVAPGDVFIPAGNTGMEPGKTSFFQALGVPTKISRGTIEITSDLKLVEAGSKVGASEATLLNMLNISPFTYGMGVSQIYDQGQTFSSSVLDVEESQLLTAFSSAVQTIAAISLALHFPTMPSVMHSIVNSYKNMIAVALETEYAWESIEELKDRVANPDKYAAAAPAAGAAPAAAAEEEKKEEPKEESEEDEDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P807</accession>
    <name>A0A6A6P807_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Mechanosensitive ion channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_384481</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P807"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000345">
        <property type="entry name" value="Mechanosensitive ion channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF15">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="488"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="726"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="893"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="897"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2460075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="941" mass="103917" checksum="27803525FC7EBF6B" modified="2020-06-17" version="1">MSTPIDEKNEPRYRPVTGGRHSDEEGTVVGDNDSPSVNRAPRDDLTIQVEPIGGRTMRTMASPSQSREQASRLGDDLAMLEAERQASQAEENNAMHRTRSRRQDPVDEFDVATNPLHEKAALYKPPENPSTSISKFFKKVHNSNFLIRYFTYIIPLACLILIPLLLGALVFTDATVGDVELMWFCIWLEIVWLTLWAGRILAKCLPYPIGLVSSLFTNNNKKWRDMGKQLEIPATIFFWWLAIEISFFPTMTNHHVDGNKAHRDWENTMNKVLVALFVGAILNFVEKIIIQLIAISFHLRTYQDRIEVNKFQIASLAKLYKFSKEKIAMDDSEFEEQGGDSAASGVKTPGQLVDTVQEAAKKGISKFGDVAGKVAGDFTGRQVLDSNHPSQVILALLSTTSGSQTLARRLYRTFGRQETETVHAEDLKNAFDNDDEAAAAFSMFDKDMNGDISMEELEAVCVEIGRERKAITASLKDLDSVVSKLDDVFMFIVVVVVMLVFISLISTSAAGVLTSAGSAVLALSWLFAATAQEFLQSVIFVFVKHPFDVGDRVSIYGNTGAEGRGDDYFVKEIALLYTEFKKMEGHIVQAPNSYLNTLFILNQRRSGALAEAVPVTFKFGTTLEQIDQLRQRLLEFVTAEKREYQTKILTELREVAEAHSITLNVVFFYKSNWQNELLRLQRRNKFICALMVSMQELGIEGPRMRYPGMKESFPVYLQNVPYVGDPAMGHSGTPDNPTGLPRGSGGATAETSTMDGPIVPPADGNVAGNRATSASGASGSTGPVASRQRGESLAGMSRRYDFSLGMKDMSSGDFMGDVTEERSVASNDFALARQGTDASAGGSRFRAPHRNRFFGSRRGHGGGAGAGGEATQADVEAGMADIPENDAAQMRWRDRQQQQQGMQRQPTMTQVPSRLDPRTGTEGPQAVRGDGGNGQFEMRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Q8</accession>
    <name>A0A6A6P8Q8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_280137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF21">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="540"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="573"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="690"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1472"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="598"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1727"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="976"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="598"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1779" mass="200451" checksum="4DF9F0796D8D5EFC" modified="2020-06-17" version="1">MASALPKLPAGHNDLISYIAANPDKPMSELMRPYREYDAALRSVYAQDPKTAASIFGNHVNNVPLFDGKESDVKIRARNLDAEPKEEQECYIMPLDKTTRKPKGAPAIVESLSEFQTNFNIFSESSLTDFSSDDWNNVVAAGSSVVTPLLPVPKKFKESKRTLRQYYHDIFAPASDVDLFLYGLSEKEALDKIKLIEAKVRNCVLSETTTVRTKHAITIVSQYPTRHIQIVLRIYKSISEILTGFDVDCSCAAFDGTQVYVSPRALAAYMTQLNTVDLTRRSPSYENRLSKYSHRGFEVYWPDLDRSRIDPTIFERSFKRTVGLARLLVLEKMPTQERREKYQDQRRRERGRPPLYRSRRQDRRLAGNLKQTYEDEVAEWEGFDEDVSDYHTFSIPYGPKYTLKRIEKLLYTKDYLLNAEWNKSRERKVNLHRHPVFFGSVEDVIHDCCGFCPKPCTPEEKEVAEEEAKIYISGDIAFIKDDPGRQSIGSFNPITGTDWTEMAFVGNTTRLCQAIIDHDLEHVEDWLSHPESDVNCRDYTGRTPLQLAVMSSSPEIVKCLIDRGARLVARMADGRTALHLAAERGNVEMIRLIMDKSEQNEEEEARRSDARNAARRAATGTTIADNAENVSEGSGECIDDSDDEETARSTTTGSFVKVDRDELRAAQSESLPLDKDEPDFYDINVAMWDNGCSALHLAIANGHVEAVQELVKSYGADILLSLPLFHPGSFQPYTVILNLCLALKLPTDQAKTMFSTLLRLGASAAQADKNLRTAFEYISCRDIALVDEVLETRMDDVKRVLNNLSIADGIYSPCPSSPLLTAIHAQKQDIAFKLLEIGAKREVTFDDFVKSFMVVYPTQYDGTQHKERLFAECVEQPIVVAVGAETLDVAMALLRSGVAANVLTAEGRQHLRLKSAARPDIGYTLLELVRLRLDKLRDYEHEPFHLNNIEELDDEASYLNGLTEGTYSHWAARIMVQEAKKKNDGLRKANEKKEKEAIERKGVDIKKTKVKEYLQQLELFEKELILKGAKTFDELYPDHEEKPPPKRPHLGYRRPPQSKFKVEFNFRAPALTDTRRDGYIRLFEAAWSGDLRTVKELTLGTWGKDNDQPPLKIAVEGSSHSNPLSLAILRGYYVVAKGILEIAQAQYLNQDQGSHRFRYVAEPGDDFSDVSSVDEADDGGLGIYRELVDDQYTIENIGEVSKTVKSTVSPVNFLNMGPIFIDLGLDGDPFSLSKYKHLENEKDDDNLVTRTVQNLVQFATWIYDMELLRFILDLGADFQAREANAGCVSSRIFQVSEADLEYAMKLGRTAILAEMLRRTGAGVPLQNLLEKSGVEVKKKPQYYCGLTVRGRKRTDWAESYSGSRSAGRLENSSPPLLRAARNGNLDSVIWFSSDAPMRYYREFVAQNKSDERLKDLSKTPGGIENLLSTWLATGSELVIHCAILSQKAEGRLALLEHLVKTFPEFIEARSSNGYTPLLVAFKLGCVAEARCLIEAGANQACRNKLGNNLVREVLGNLPHNDKDSAEKLREMLSMLDREILPSLLMDRHVSSRSTPLSGYIDATGAKGTTTDQTVARTVKVLLNFSPDANELRTVDGGGDTPAHLVVRFSFPRTLRVMLERDPEILMRENSTGRTPVEMARDFVITKRVTERTWHPYDRRLSYFTSRIPYETVVSRSPESFVEEVRPNKGLSPQERVLGVCEEMVTKLPYPRKRRMVTLAEANEVARRLASTNSASRVPVKLNDSDSESSGGQTEVSDADNEVDRWISSAPAWVGWKSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Y5</accession>
    <name>A0A6A6P8Y5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_270847</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Y5"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031106">
        <property type="entry name" value="C/EBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334:SF20">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334">
        <property type="entry name" value="CCAAT/ENHANCER BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="60"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="120" mass="13290" checksum="028B8D2CE92A0908" modified="2020-06-17" version="1" fragment="single">STSQPLFTVSSSTEPLYGSSAPNLSPSATFEPSPASSNSDSRVHTKSSSRGPSPPSSTTESKIIEKRQRNTLAARKYRQKRLDRIAELERALEDVSRERDDLRVQLARRDAEVTTLRGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P919</accession>
    <name>A0A6A6P919_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_335549</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P919"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF131">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025712466" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="530"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="577" mass="64108" checksum="293A3538E5317557" modified="2020-06-17" version="1">MRDNMRLTIASALVALFAGSSNALAPPLEHPRHSVKEPRQLPPFPEGLKTIVSPTNVTIRYKEPGNEGFCETTPGVNSYSGYIDLAPNAHAYFYFFESRNDPANDPVTLWLNGGPGSDSLIGLFQELGPCNVTEELETMYNPYAWNNVSNMLFLSQPFGTGFSYTTMEAGSMDNVTGAFVDETVQSVTGRWPIADAEHIDTTQMAAVAAFHIMQGFYSALPQLDSEVSSKIFHLWTESYGGHYGPTFYDYFYEQNQLIANGSMPGTELHMDTLGIINGIIDSAIQTPYYPEFAVNNTYGIKAINDTVYNFMKFAWSMQDGCADYISYCRAGNKSSLSGEAVCSQAQAVCRLTVEYPYYSYGGRGVYDIRHPYDDPTPPDYFIDMLNTAEVQNILGVAVNYTTNNANTYYAFAQTGDFVWETYMEDLEYLLDQGVRVGLIYGDADYICNWFGGEAVSLAVNYTDADAFRASGYVPFTVDDTEYGEVRQYGNFSFLRIYESGHEIPYYQPEASLAFFDRTINHMILADGSEPLTDDYGTEGEPEATHTNPFVPLPSSTSSAAGEEETGGVWDVPIYWDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P997</accession>
    <name>A0A6A6P997_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SART-1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_165774</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P997"/>
    <dbReference type="OrthoDB" id="5583at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="279"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="507"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="452"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="644"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="672" mass="75938" checksum="1C8C88478CFABEB1" modified="2020-06-17" version="1">MADPSIEEMNRVRVALGMKPLPMPNQPSSGGEGPVFRESKKDGASSGSDEEPGSTLDSRHAAASNNWQKLQEEQQAKARREERKVALQKAREKAQREAKLEGKGLGDADEDVDTKTWLKQQKKRQKAIEKARKLEEELAEREKLAEYTEADLAGVRVGHEIGQFEEGEEQILTLKDATVDEEEDDELENVNLRDKEKLGEKLELKKKKPVYNPNELAENGESSILAQYDEEIHGKKKNRFTLDGKGSTKEVAMRDVQAGSDKPKTLKISLDLLKDDAPLSDYVEPSEIKMKKPKKPKKSKSSKKRVLDDDDIFAPAEEAPVDPNAMEVDTNGKSSESKKRSLEDSSFVDDEDLQASLAMQRRAALKQRKKAKFEDFARQLRDEGSATPGVIDTTEAQDDEPGLVIDETSEFVANLQKPGEEEERKRKPSRGRSRTTSAPPKASSPDSDGDVDMDRSYNDTDEATAKESADRGRSTSHDITHTGLEEEASLNDGIGATLKMLRERGLVQRSAGDLTDELRHRERFLTEKRKRQEEAERRARLQRERDRQSGKLDRMSAREREDYARHNNTVRDQIEARQMAEIFNKEYKPNIDLKYVDEYGRHMAPKEAFKNLSHQFHGKGSGKQKTEKKLKNIEDEKKREAMSSLDSSQHTGMNSALNSTARKNRQAGVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9T5</accession>
    <name>A0A6A6P9T5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cnl2/NKP2 family protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_369604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9T5"/>
    <dbReference type="OrthoDB" id="2311687at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031511">
        <property type="term" value="C:Mis6-Sim4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018565">
        <property type="entry name" value="Nkp2/Cnl2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28064">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT NKP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28064:SF1">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT NKP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09447">
        <property type="entry name" value="Cnl2_NKP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="23321" checksum="6E94F3E706A5A677" modified="2020-06-17" version="1">MAPTEASILSSFLLSPAPLPTFLTLRQFKELFPRSQQSDPQIQTLYRELQHQRAIDIDDVRRHIAAEVKRGKRQKRSVVEGRRKMHDGDFGQAHDRETRMELELSGALGQPTSEEHTPETIVPAMESARSQMEAEVVAMESEAKALMEDVGGIISDLSDLRYGRFNRVAGSENDLGQEVVEDLARLVDICKQSLSESYVTRLGRQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9U8</accession>
    <name>A0A6A6P9U8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_369299</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9U8"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="10">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="88" mass="9742" checksum="0779177B5E0635B3" modified="2020-06-17" version="1">MSVYDEIEIEDMTWDAKLQIYHYPCPCGDRFEICVADLRDGEDIAVCPSCSLMIKVIFDKLPPLWESRPDDIPKDGGPGKAAPVAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAB2</accession>
    <name>A0A6A6PAB2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_333511</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type III membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OST4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAB2"/>
    <dbReference type="OrthoDB" id="2124077at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018943">
        <property type="entry name" value="Oligosaccaryltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051307">
        <property type="entry name" value="OST4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036330">
        <property type="entry name" value="Ost4p_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48164">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48164:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10215">
        <property type="entry name" value="Ost4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103464">
        <property type="entry name" value="Oligosaccharyltransferase subunit ost4p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="6286" checksum="238783A42F519904" modified="2020-06-17" version="1">MISDTSLYTLAVFLGSASMLLIVLYHFLEVNAKDTAALSDERKADSLPAGAAKLRRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAD7</accession>
    <name>A0A6A6PAD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_333878</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAD7"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15898">
        <property type="entry name" value="EFh_PI-PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="113"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="304"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="421"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="528"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2460951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="621" mass="67724" checksum="18C686DADABE567D" modified="2020-06-17" version="1">MNHESGNAQDARVESLWTQLDTRGTGHLDLSGLKKGLRKLDHPLKNADGFLKELLEAVDTNGDGRIEYSEFRSFVKETERELWSLFRSIDHNGDGKLSKSELREGFRRAGLAVPNSKLDHFFAEVDTNRDGVISYEEWRDFLLFIPAEAPSLKTVLSYYSSTVMVNPEGDVQISDETIEGLGITIARFLNLFFGSLVSIARAQPSSARSRASAPDALLPLPSLDSSSTPQPSSLDATCDATASITNSSSATTTPSKTTRMQYHPPEAVLDEPSPSPLAPVPAVPLPESDWTKWENLKPVLISFIPNSGYFIAGGLAGIVSRTSTAPLDRLKVYLIAQTSVTKEAVQAAKSGAALHAVKMGWRSLESATKELWRAGGLRSLYAGNGLNVVKVMPESAVKFGSYEASKRIFAKLEGHNDPRSLNTLSKFLTGGIAGIISQFVVYPLDTLKFRMQCETVAGGLHGNKLIFATAKKMWAQNGMRAFYRGLPMGLVGMFPYAAIDLGTFEYLKRTITARNARIRRCHEEDAQPGSVTTAAVGGFSGALGASMVYPLNLLRTRLQSQGTAQHPRTYDGIIDVTRKTIQGEGVRGLFKGLTPNLLKVVPAVSITYVVYENTKRAMNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAN4</accession>
    <name>A0A6A6PAN4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAN4"/>
    <dbReference type="OrthoDB" id="3935484at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="29884" checksum="13B3BADD92050C45" modified="2020-06-17" version="1">MLELPITPECSVASSLSMADAASLIAACGILHPVLTRAVNWLSGGRRSELSNESAQWILREFEALFAAACNRARIAFVGLGMQEMRLPNASFERGHRVISLKRDVINKGLTNGLGGRFRCNARYSWAPGDLDWNLRGTHNSATWPWGPDDYGKVDMVFVPKDPGIFPGITAAFVRSDSENPVVISSLAMYNVLATDAEILDAVETGDVKRTLGLIREGRGSAGDRDAKGRSLLSIAKERGDWNMYQLLIMKGATPLHDLPECMSEVLELPQPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAU4</accession>
    <name>A0A6A6PAU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_403323</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAU4"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="305"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="43568" checksum="DCC269164A7B2D53" modified="2020-06-17" version="1">MPPKKEVKQEKLPLGRPGNNLKSGIVGLANVGKSTLFQAITKCSLGNPANFPYATIDPEEARVIVPDERFDWLCKHYKPKSEVPANLTVYDIAGLTKGASTGAGLGNAFLSHIRAVDAIFQVVRCFDDAEIIHVEGDVDPIRDLNIISEELRLKDIEFAEKAHENLVKQTRRGGQSLEMKKLREEQGTVEKVLDMLKAGKDVRKGDWSPKEVEVINPLFLLTSKPVVYLVNLSERDYIRQKNKHLPKIAEWIKENATGDPVIPISVQMEERLAVMPDTEAEEELKKLGTKSSLPKVILTMRKALGLISFFTTGADEVRQWTIRQGTKAPQAAGVIHTDFEKTFIQAVVYNYNVLREEGDEAGVKAKGKVMTKGKDYVVEDGDILLIKAGAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAU6</accession>
    <name>A0A6A6PAU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">superoxide dismutase</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_138163</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAU6"/>
    <dbReference type="OrthoDB" id="159229at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000007">
        <property type="entry name" value="Cell surface Cu-only superoxide dismutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053257">
        <property type="entry name" value="Cu-only_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20910">
        <property type="entry name" value="AGAP001623-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20910:SF1">
        <property type="entry name" value="SUPEROXIDE DISMUTASE COPPER_ZINC BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025551394" description="superoxide dismutase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="10">
        <location>
            <begin position="42"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="262" mass="25856" checksum="DFE18585477A271D" modified="2020-06-17" version="1">MRAAATIFALLGAVGYAVADDAPVVTDNPTGAIYNVAFEGNVNGIVVAKTHADGTGVDFSLALTGLPADQGPFGYHIHQMPVPADGNCTATGGHLNPYDAEGDCVSDTPAACEVGDLSGKHGKLSGNSTAFAATYVDEYTSLVPDDVAYIGSRSIVIHLADGSRYACANFVNASPSGVLSSISSSNSASPTAALNSTLTSMALTGTGAATHTASLGLSATSSPATSPSASASTTPEPVGDNPASKTMVSAGAVLAALGAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB32</accession>
    <name>A0A6A6PB32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Complex I intermediate-associated protein 30-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_140009</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB32"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010257">
        <property type="term" value="P:NADH dehydrogenase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF19">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="3">
        <location>
            <begin position="14"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="29716" checksum="3253C73D027EF9D4" modified="2020-06-17" version="1">MKRKLFLFGGDKPWDSSEWTASDDRVRGGKSQSYLDCSSSCSTAKFHGTLDIATLGGAGFASQRTAGNDRNWDLSDYDGIEIKVAEADTKRYTFIVKDTLLPRNPDNGREQATISWEYDFCVSPSELERGSVATFWIPWSALKPTYRGKEKKHADKLKTAEVKRFSIMNRSFFGDQEGEFSLSLQSISAVFKCESEDDVTSETQTLATDLAEAEKGWASEKEKAMLELNSQANGEHVGRPRYMDVGVTLWWVIFWGAVVILLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBD1</accession>
    <name>A0A6A6PBD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_137726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBD1"/>
    <dbReference type="OrthoDB" id="5413908at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025436462" evidence="1">
        <location>
            <begin position="18"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="26255" checksum="0871C9471BECAC66" modified="2020-06-17" version="1">MLYTHALAVTLLLRILAFDIDNPAGYSFSADALLAGPHVKNYGMIQPRREQPPPPLDLHALDSKLLYLRNATTPPPDHASRIDNARSLECVAREELEKQGCPPCHPVDLAFPICDPPWRIPRESHRKSGKVFLRAQLSDCLGFRRFQEATRRYYREHKTKAFREFEHVCERRRQFGPGEDVHLRPEPGQQSRLENWVEFQNYHLHIHEEMEQDIQKEKTAFDKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBL4</accession>
    <name>A0A6A6PBL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP citrate synthase</fullName>
            <ecNumber evidence="4">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_334584</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="4"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBL4"/>
    <dbReference type="OrthoDB" id="5295093at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000004">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.110:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032263">
        <property type="entry name" value="Citrate-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056749">
        <property type="entry name" value="Citrate_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF10">
        <property type="entry name" value="SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16114">
        <property type="entry name" value="Citrate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24948">
        <property type="entry name" value="Citrate_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-citrate synthase ATP-grasp" evidence="15">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase citrate-binding" evidence="14">
        <location>
            <begin position="299"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="487" mass="52668" checksum="07860691B6F31EDE" modified="2020-06-17" version="1">MSAKSILEADGKAILNYHLTRAPVIKPTPLPPSATHNPAPRLASLHFPEDATVEAVLDQAEVTYPWLLAPNAKFVAKPDQLIKRRGKSGLLALNKSWADARAWIAARAGKVQRVESTDGVLRQFLVEPFVPHPDDTEYYVNINSVREGDWILFTHEGGVDVGDVDAKAEKLLIPVDLTQYPSNEEIAATLLKNVPKGVHNVLVDFISRLYAVYVDCQFTYLEINPLVVIPNADATSAEVYFLDLAAKLDQTAEFECGVKWAVARAPANLGIATAPAVTKDAKVTVDAGPPMEFPAPFGRELSKEEAYIAEMDAKTGASLKLTVLNANGRVWTLVAGGGASVVYADAIASAGYASELANYGEYSGAPTETQTFHYARTVLDLMLRAPMHEEGKVLFIGGGIANFTNVASTFKGVIRALREVAPLLNEHKVQIWVRRAGPNYQEGLKNIKAVSVELGLDMHVYGPEMHVSGIVPLALSGKTSDVKEFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC96</accession>
    <name>A0A6A6PC96_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC96"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="32202" checksum="7E365841A09522B3" modified="2020-06-17" version="1">MSGDYFGLPIDMSGKTWVDRHGSKRTKPMEVLVLGMPRTGTASMRMALTRLGYDHVYHMASVFHNPPDADIWHEAAAAWVGKRKPLTREEWDQVLGHAMAVTDFPAAVFWKELIEMYPEAKVVLTNRDRDAWWKSFNATIGASIKKMRSSWLATIDPTFVGRIRPMAYNMFGQYFGTMDVDEARYKEVFVQHYDNIRKATPPERLLDYNVSQGWEPLCEFLGKPVPEEDFPRVNESDYFHKTMGTIMGLRMQIAVKRVLSMAAPIVVAGVAVYFARTRGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCG6</accession>
    <name>A0A6A6PCG6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_92628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCG6"/>
    <dbReference type="OrthoDB" id="5428055at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="287" mass="32929" checksum="7F462CD647A35406" modified="2020-06-17" version="1">MAATDIFVTQFHIRYFDLEKRERPPRGAGNGDGGGGGDAIPTSRDGNAGAHYFPGIQLRREMGVLLGGSESSDETAVVERRVSLLLASSLREMPARWSVTTLMPPSKQQRREYEPFYEHDVLPVGRDGDELGNLFGVGVFIKAIDRTLKDCFASWNGVLRGLDEELMSTVTAILDPVKRHALMFDDGTFSRSELYFVVLQLLLVFADHVEQTVEDVRDARRQCMWLLQRRFPRPEEAQIRALIRIEERWRRLLDEQEERAESLAQRLHRKRQEIESLRHGVRFSSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD36</accession>
    <name>A0A6A6PD36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="7">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_93450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="7"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD36"/>
    <dbReference type="OrthoDB" id="3781271at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025526889" description="(4-O-methyl)-D-glucuronate--lignin esterase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="4-O-methyl-glucuronoyl methylesterase-like" evidence="9">
        <location>
            <begin position="89"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="41570" checksum="A1D08CF76AE8C9E6" modified="2020-06-17" version="1">MKSIAIALGFLSLAAAQDVCPTLPADINFSEPALPDPFVALDGSEITTVDAWECRREEIRDLFQRYELGPKPPKPSEVSASFSGDQLTINCSEDGSSISWSVQISYPSSGQAPYPAIIGYGGGSIPTPAGVASINFFNDEIADQITYNRGKFYDLYGSESSSAALIAWAWAVSRIVDALEMTPDANVDTNKLAVTGCSRNGKGAMIAGAFDDRIVLTIPQESGSGGPGCWRLVQQQKDQGGSVETAGQIVQGDAWFSRDFSSYTDRLDELPYDHHMLTGLFAPRGLLIIENTAFEWLGDMSTYGCSVAGQKIFESLGAGDNMGYSQVSHSDHCGFPSSQQPELTAFFDKFLLDRETDTDVFKTDGNFNFDESQWIQWDVPELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD41</accession>
    <name>A0A6A6PD41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protoglobin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_331867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD41"/>
    <dbReference type="OrthoDB" id="10027058at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin-sensor" evidence="2">
        <location>
            <begin position="19"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="34081" checksum="F5CC8A7E0141F557" modified="2020-06-17" version="1">MASRRVQHIDRKDLYTSLEARIQYLHSFLDFSSNDIESLIVGSKYIRALIPALVNIVYKKLLQYDITARAFTTRSTSYDGPVDEMPDENSPQIQYRKMFLRGYLQKLCSDPSKMEFWEYLDKVGMMHVGQGRKHPLHVEYIHIGACLGFIQDVLIEAILSHPRLKIERKIAIVKAIGKVLWIQNDLFAKWYVRDGDEYAADRGEVEIEREGFLHGKQVNSEAGEQQGGGAGSDEEATLTPTTEVPVGQCPFGGLTQAVGNVSLAKDPQSPQQADEGASSTSRPLSASGIPRPVDKKSAGGALAEAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDH6</accession>
    <name>A0A6A6PDH6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_3243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDH6"/>
    <dbReference type="OrthoDB" id="3057168at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="13"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="541" mass="59428" checksum="2F04C556DF31F17D" modified="2020-06-17" version="1">MPLVGPSKYQNNKRLIICCDGTWFNSDNGWVEGTLLDPTGHLQTPSNVTRISRAIPAKTFDGHDQIVFYQSGVGTSWSTVERYVGGATGEGLSENIREAYGFICNNWAEGDEIFLIGFSRGAWTARSIGGLIGSMGLLNKEGLPFFYDVLKDWENAGSLKYKPKLPSALADFKLEAVPGNAQDYLSDYKAKLKHMGMIREPRVMAIGVWDTVGALGIPVSPVMSKLCLPTTVNEYRFNDTGLGNHIQNAFHALSLDETRSPFSPTLWERPPGCHTNLKQVWFPGSHADVGGGYDQTAPADISLAWMMSQLHYCGLEFNRLYVNRLPSLPFSMLRPAPLYATGNPEPKPKQSGLFSTKRATDGNSPFRGWAQGTLHTTQGFPSNLLFSKPRTPGLYRRVDGGTGKRTGHALSDTCEFVHASVRARILLRGPKANDKSGVYRPKALAGWALQDEGPVLQHADTVLGGASSQHEAADKWSAEDGGDWSQRAKDVAQRHSWVYRGRDKAGYEEGHAKVLREDELGHYELELAKMDPLAARAVLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDU4</accession>
    <name>A0A6A6PDU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_276924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDU4"/>
    <dbReference type="OrthoDB" id="5309565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40460">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40460:SF1">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="Hypothetical protein YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="19006" checksum="826CE30BAC6C46DD" modified="2020-06-17" version="1">MSDKNTQPSTLQSVVDSAGAAAQSVVGSVTGNKADQTQAQDRQAKAETESDLSHTTAKAGPMTATPDGVAVDSEERRQGSWNQTIGSGKEMLGNVVGSENLRQQGIRQNQEGKEQEARGQLSDYGSGIKDRVGGAVGGAAAALQGDREEQERRMAQHDVGKTQQRGVEADLQKQVEAEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDU6</accession>
    <name>A0A6A6PDU6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Indoleamine 2,3-dioxygenase</fullName>
            <ecNumber evidence="5">1.13.11.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_277485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Produces N-formyl-kynurenine through the oxidation of tryptophan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.52" evidence="5"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDU6"/>
    <dbReference type="OrthoDB" id="540174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.480:FF:000004">
        <property type="entry name" value="Indoleamine 2,3-dioxygenase subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF5">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00876">
        <property type="entry name" value="IDO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="496" mass="54914" checksum="0ED2B7AC59F2A254" modified="2020-06-17" version="1">MFPPIPRLEDYDISPEHGFLPSEIPLEVLPDHYYAPWETVIRNLQGLILSRRLHGVVDKLPVLSTDYLLTEAEWRRAYSILAIISHAYIWGGDTPCDTVPPPISIPFTSTCNHFELPTVATYAGLTLWNWRPLFSNEPIDNLENLSTLFTLTGSLDESWFYLVSVAIEARAAPIIPLMLEAVAAARRNDSITVTECLRAFAERLDELGGLLQRMYENCDAHVFYHRIRPFLAGSKNMADAGLPNGVIFDDGTGTQPYVQYSGGSNAQSSVIQFFDIILGVEHRPTGQSAPDGNGNAANGSENAAGVDAVQSPTHNFITEMRRYMPGPHRRFLEAVASVANIREFVSRRKKRDGALTTAFDACLAMLRAFRDKHIQMVSRYIIVKSRESRSHSRSMSPRQQAPRVNLAGADDDEQQRRRLRGTGGTALIPFLKQARDETGEPAIDAWARRLLTNGPADASVGARLTKVGEHASGEMEIVGLAGTWSVDDSEGGICHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDY3</accession>
    <name>A0A6A6PDY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S7 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_277574</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDY3"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="67"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="23632" checksum="0F68D43FD10E6331" modified="2020-06-17" version="1">MSEGGVEVESPQFPVLPKDVTEEIGSIKLFNKWSYEDVEIRDISLTDYIQIRTPVYTSHSAGRYAVKRFRKAQCPIIERLTNSLMMNGRNNGKKLMAMRIVAHAFEIIHIMTDQNPIQVAVDAIVNCGPREDSTRIGSAGTVRRQAVDVSPLRRVNQAIALLTIGAREASFRNVKSIAECLAEELINAAKGSSNSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE48</accession>
    <name>A0A6A6PE48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">D-arabinono-1,4-lactone oxidase</fullName>
            <shortName evidence="9">ALO</shortName>
            <ecNumber evidence="4 9">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_412524</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23756"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16292"/>
            <dbReference type="ChEBI" id="CHEBI:58277"/>
            <dbReference type="EC" id="1.1.3.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="4 9"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE48"/>
    <dbReference type="OrthoDB" id="610608at2759"/>
    <dbReference type="UniPathway" id="UPA00771">
        <property type="reaction ID" value="UER00766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030654">
        <property type="entry name" value="Sugar_lactone_oxidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01678">
        <property type="entry name" value="FAD_lactone_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="11">
        <location>
            <begin position="43"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="389"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="610"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="639"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2462037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="675" mass="73515" checksum="B34EBE7034FC2C46" modified="2020-06-17" version="1">MASLSSPPPPPPARLEAELAKLDPAVPFRATRAHRHRTWARTFHSRPELYITPETLPEIQKAVTLARRCRRRLVVVGAAHSPSDLTCTSAWMLSLDRFARALRVEPRARTVVVEAGMRLRALNLLARDRGWTLPNLGSIDEQSVAGALATATHGSALRHGLLSDAVRSLRLVLGNGSCVLCSREQNVDLFRAALVSLGALGVVVEVEVALAPAANVRWEQALQPLAHVLDTWDSTLWSSAEFTRVWWLPYTRRAVVWRADKTDEAPRPPPKSSWYGGSIGSHTYHALLWLANHVPRLLPLVERFVFGMQYGFRVGESSRTEAVEEMRTGLLMNCLYSQFVNEWALPLDKGPEAITRLGAWLNGDEQTARIPFSSKGVYVHAPIEVRVSDGSVTSSSSSGSSSGSGGSGSPPEGTAATGGPRLRAFLDPTWPDSPTLYLNATLYRPYGADPPCTPRYYQAFEYLMRDLGGRPHWAKNFGASPLGPVTHADLRRMYGADLDSWLDVRRRCDPEGMFVGGWLRRVVLPPPPPPREDEAREKGAEAEGEARLAVMPLEEREVCTRPRRRRGGGRDWFGEQAGADAATAVAAAAAVAAAAAAVADKARAGNAALERSSSEESFDVMHGAEAEASTLLAARGEDTTEEEDEGEDDDDGTVLARVKEGAAEGLMGTRVFEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEB9</accession>
    <name>A0A6A6PEB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleoporin complex subunit 54-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_368383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEB9"/>
    <dbReference type="OrthoDB" id="6162375at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024864">
        <property type="entry name" value="Nup54/Nup57/Nup44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025712">
        <property type="entry name" value="Nup54_alpha-helical_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000:SF0">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13874">
        <property type="entry name" value="Nup54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup54 alpha-helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="400" mass="44568" checksum="BA683DE6FDA859E4" modified="2020-06-17" version="1">MSLFGNLGQSQQQQPQGGLFGSTNQPQQQQPTLGGSLFGGLGGSQQQQQQQQQQQQQQQQQQQQQQSQQPQQQTSSLFGRPPPNQQQPQQPQQPGGSFFGASQAGSTWGVRPLPKLGQGGKESWPYGSDMASRGPEKSIPDQMTTLAEKWSPNHPNCAFTNYFYNQVHPDQVPYYGPSADEDRHKWEAALARKPGPGSIPVLGRGFGAIAERLSIQSRSATALQARLHEINDALVALMQKHELEVSVRTQEARRRHGVLAQRTLALATKVQVLRNRGYAMEAPEEQLKLKLAELERLAFDPALTGTQEEIWARMSAVRARATRLQADVAKMARGNEEKEEAPEGIDEEIMIKLEKALKNCDAHIDQLKKELELLTKDFNAWLGLPEEDKDKDKKEEDKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKY7</accession>
    <name>A0A6A6NKY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_294764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKY7"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000870">
        <property type="entry name" value="WD repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25174">
        <property type="entry name" value="Beta-prop_THOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="76"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="322" mass="34409" checksum="17C71F86124CE4E3" modified="2020-06-17" version="1">MAPRGRSLPKAAFAPVFAKQKTTTYSDLPPQRVTSAHALRSVAWNPLGTLIATGAGDRTLRIWNPEKSQVKNSTELRGHSSAVERVAWNPEKEAELASCGSDGVVRLWDVRSKGSVGEVKVAGEGFTLAWRPDGSELLVGTKDDTLIPISRSTLTPLASHRQPVQTNQTMFSHSGNELFLTTGEGHVKILDYPSMEVLHTLNAHTSSCLSLDFSPTAAYLAIGGSDALITLWDSYDWVCGRSLGGMLGSVRSVSFSFDGSYIVGGSDEGASLEIAHVETAEYVHHVETDAAAPCVAWHPSKYVLAYSGDVQGLKIIGSIGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLA3</accession>
    <name>A0A6A6NLA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLA3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="63" mass="6936" checksum="34D523BE0D331AA3" modified="2020-06-17" version="1">MFVITNFVFGGGAYSAVVDTAGHMAYLVTNITFLNIIKRLKNLPRSGWVKWAVLSPETVSGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM12</accession>
    <name>A0A6A6NM12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_153762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM12"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="27405" checksum="6C264E3AF8F8D008" modified="2020-06-17" version="1">MVGSSTYLDHVGCKFPKRMERLQRVRCDTPRFAGMLKPRGQFQRRGQRERGEQKGTLGWRRWRKKGGCGPRRAGEAKGEGEMARGCERGRDGGCGPGRQRDGKAVVEERRCDAGRAIGLLDGQQNERAREDERTRERRRQTVGAARSGGALARRSNVDLRSGDLFCVRARTQGVCSGPSARRGRSGKCRRAGAGADDGACVRCVRVRRPESERTGLRVAVVVCRGRRRRGGWKGRKNRWRLSLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM70</accession>
    <name>A0A6A6NM70_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM70"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="199" mass="20802" checksum="3F8D57063887AED8" modified="2020-06-17" version="1">MLPLLAAAAAGPPPPAPRLPSTAASSSGTMALIGRSGLRCGDDTAVSGRSAKLACWPRAFLLACFACHFACSPRRLAMVVVRGVGARGRQPFDGRQAHSFPRLGRQSVSQPVGHDEWLSLCPRGGRIPERLAMDDDYGSIPKTTGCPGGLGCVWRDQRLSCSGGTAAEQPALPGTGLARGGRRNLVCSEQVRSRERVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMI9</accession>
    <name>A0A6A6NMI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM7</name>
        <name evidence="6" type="ORF">BDY21DRAFT_293734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMI9"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="262" mass="28884" checksum="38A3E3F359611E7E" modified="2020-06-17" version="1">MSDPGDDESFDMFQEPPDYFQPEKPATFATHALRSGETLHIRLVGHNPLWGHLLWNAGRTVATYLEDGAATLVAGKTVLELGAGGGLPSLVCALRGAAKVVVTDYPDPDLVENLAFNVTNCLEGSETAQRIRGGYLWGAAIDDLLACLPAPEPDAAASEPGFDLLILADLLFNHSEHAKLLATVQKTLKRSKDAKALVFFTPYRPWLMEKDLAFFDLARENEFAVENILEAYMPNVMFEGDPGDERLRRTVFGYELTWNNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW8</accession>
    <name>A0A6A6NMW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_358455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW8"/>
    <dbReference type="OrthoDB" id="1933483at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061928">
        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.10:FF:000021">
        <property type="entry name" value="Gamma-glutamylcyclotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192:SF2">
        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="243" mass="27236" checksum="E4058847DB6A1CA3" modified="2020-06-17" version="1">MASEIPNDAFWLFGYGSLIWKPPPHFDERVPGYIEGYVRRFWQSSEDHRGTPEAPGRVVTLIDRTHWDTLTDHHSSPTERVWGAAYHIPSSKVAEVREYLDIREINGYSIQYTPFHAAGPVANSTGSGPIQCLVYIGLPSNPQFLGPQDPDALAAHILKSKGPSGENKEYLYMLETALLNLSEESSDEHVSDLVRRCRSLESERGSQSFDNRAPSNQGSPGEVREELHKIGSTEEQEEVEKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNK7</accession>
    <name>A0A6A6NNK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_388290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNK7"/>
    <dbReference type="OrthoDB" id="3645574at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="61819" checksum="D9E14E252FDDFA27" modified="2020-06-17" version="1">MTSCLSKMSRSLPLLKGSITLEDALTEDSDVLHELSYPEKRLDFYVYLSEHRQHLEELVSFHLGVPKETCKAARDFREWVHGSFNACVPVYVDETAKCRVKKSQFPGNAEEKLRCEVATYIWIENNCPDISIPRLRGFGFPSGRCFTALENKPILRRIAWFFQRTTLWLFGYPTPSQYIGRQSPFSPDSGYLIVDCVEEGEMLSESWNLLHHDRKRRANLFAGLSRIMLSLARVPFPRIGPLTIDNCGVLSLACRPLTCILQQLENFGIPTDIPKDRTYVTADARIRYMPNSIHNTLDGQAQLSALTMMRSLLPHFTDRDLRWGPFILMLTDLHQSNIFVSNDWHVTAIIDLEWACALPIEMLHPPYWLTGVAIDRIVEEELEIMRKGWEIGNFWYFSALDCLNGLYSLYMSHIQRIFAATEDSGPKFDRTVSAYWTANTAEFIAAKVRDKEVYSSQLRECPKLIRLPAESSDLSSALSTDQRVHRFGSPEDLSTHFKRKHLQHIKMGQTLEGPVCEMPLDHKQHLRNHALRIHKAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP97</accession>
    <name>A0A6A6NP97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_129007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP97"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025359650" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16605" checksum="D83D13FC1BD9BBFE" modified="2020-06-17" version="1">MLYTTLEFVPVVVLVLARQVCKGKDTEEENEKEKHNLSLSVNPVPSHQQVRKRVAKKIREKSVMAHREDECLYGSTVQFSGNTVCVPHHLPNQQPVPTPFVPTKRVPPILVHNHHSTFVASDFTRYVFVGCKSCFVGLKGESIRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPF0</accession>
    <name>A0A6A6NPF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_366934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPF0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="194" mass="21906" checksum="AD9A199E10CF86D7" modified="2020-06-17" version="1">MGLGHLAKCQLDFSHLWMAYWLAKVFISRERTWQANRDLRESVLTLSDPRKASGCWLHTAYVFVVAGPLSPTPIRAERRTWKPTLGRRRACGESLQDGEDNAAAKLKICEQKPDSTHSRWLQSPPRYTPNDIALLLSLGPLHAPSHVLLEIRCISTSPASTPTPRRASRWVECSQLGISETRELTSKEVPAQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPN0</accession>
    <name>A0A6A6NPN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPN0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20132" checksum="8F153BD01C4DEBBB" modified="2020-06-17" version="1">MAACRPTNDTAELQQEPQHRAQARLHLRIRAPKLQIVTRPRPRGGTSCRRFGRQVAYGEIDSNEKENYIARRTLSSWLSPKWCPARGQRLFAARPTDSISLPPLCILCITPAEAAYALRSQAPTRQAVHRTNASDRRTTQIAVDIKFFDEYEPKGHNSSSRGSSTEFAGPSAWVRPFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPN9</accession>
    <name>A0A6A6NPN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_127821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPN9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="16888" checksum="90CC7F5C2FBE2C8A" modified="2020-06-17" version="1">MWRNKGRCEAVEVGRGGALGRGRIDKATSELGAKHSTTVTRVCAYPPGICSVPTYLLRHGAGPATPHAHAHEQLQLAAILPRGAPKHRQHRGRLCAEARARAEEPWAATQVGPRHGDACRRPTTCLPSRASAAAWPRPLQQTFAPPHIPRLTHSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU5</accession>
    <name>A0A6A6NPU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_119615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU5"/>
    <dbReference type="OrthoDB" id="21413at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019212">
        <property type="term" value="F:phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024325">
        <property type="entry name" value="DUF3835"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039553">
        <property type="entry name" value="Prefoldin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111:SF0">
        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12927">
        <property type="entry name" value="DUF3835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13758">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3835" evidence="3">
        <location>
            <begin position="609"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="698" mass="76661" checksum="44A2C0A1D7A3F27F" modified="2020-06-17" version="1">MANRVRDSMADLERRRLQLEDNVAKLRNALRHWQTLEAEYNGIKDELENLGDDASPEEMMNVGEDFGSDLVSCKELEDIIGRDQARMRSPRQVADVISKRIEYVKKNVQSVQKQLSNAEDKLAGVLVVSNPDLKDEADLPVTEILEELDEDGNVISSSTRAPGAEHAQLVEALRSAGISIPDGQDRQQPEESQPDKSTHRAITQDPHETGPPHYPTPKTKLLVPSKNEQSSSRVEASRTLHEPGITGAVPGSTVGHFEGEGSSNLTPESGDAIMPGTIQLPRTNATDMTHRSADGGATGGSTSSAKSSGEQTNIKEFPVPGTVGKGDRILELNDDDHVVGSVPIMPAGESSEDARLRREMLQYAMNEISPIVAELDLEEAHNDDSDYDDEEADEDLEDADDDDLSEEDDWGRSLRGGISDDYRERMMALEKKLNAHMIENVGPGLVTNARAPNGVENDARRLVVKPDEDIEAINGVRLSGEEPANFNVAERIPKEGKKGVRFADELDILPESKPAKKVETRPPRAKEPRVPAMSNVVVERNEVKQESTTSSRHSSRFKTARNSATARAPQASPNDKNAAYEGLAKNPEIGKADANSCNQFIGRTLLGPVVEKPMSGPLAPPEDSSLDHALHQREIFTAYHTARNRMIQKQGGFDPSPEDIVDPLYEEKNGKIKKVSRFRAARMKFNQFRLDIAADNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPW3</accession>
    <name>A0A6A6NPW3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_355242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPW3"/>
    <dbReference type="OrthoDB" id="2261376at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="310" mass="33928" checksum="934B20BE34C2DE05" modified="2020-06-17" version="1">MIVVLATTEDHLRAAWRVCLGLGVVPPLSLLYLRIKLQEPEAYKRETMAHAQTPWLLCAKLYWFRLAVVSLIWFVYDFSAYSFGIYSSSILDNLLGDGSPLWKSFGWNVLLNFFYMPGCILGSFLADVPWLGPKRTLAAGVILQGIVGFIMAGCYSYLNRPENVAGFVVVYGVFLALGEVGPGDNIGLVASKTSATAIRGQYYGIAAAIGKVGAFVGSWLLPVIQNNAPNETRAGQDPFFVGSSLAIFSGCLALFLLPEIGQDTIEAEDVRFREYLERNGYDTSAMGIKETQTVEGRAEESSETEEQSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ22</accession>
    <name>A0A6A6NQ22_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_401258</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Preautophagosomal structure membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG12 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ22"/>
    <dbReference type="OrthoDB" id="10003551at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000148">
        <property type="entry name" value="Ubiquitin-like protein ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5 10" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="17663" checksum="D37C5CE1EC0C67D2" modified="2020-06-17" version="1">MTDPSASNPAGGAGPPDPAGASTSSPGPSTKKTASPSPSPPRPSSPSSSSSSNADLPLTTAASAVLTALPRDTRAALSSAGELGLPKVTVRLQPVGSAPALRQRVFKVGSGARFETVVRSLRRKLGARDHESVFCYVNSVFAPGLDEGVGNLWRCFKTKDELVVAYSVTPAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ39</accession>
    <name>A0A6A6NQ39_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_114088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ39"/>
    <dbReference type="OrthoDB" id="3486565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="265"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="684" mass="77172" checksum="D82613A8D6861830" modified="2020-06-17" version="1">MPSLECVKLFEARNSPEYLCSAYDLANRTHSNMWRGIQRSLPTRPKQKLEDENQIHSEEVENGSWVEVVTTKRVNNLADAELCSRCRGLIINLPVEPQGAEIFQAYCGAKFFIGYASEILSAYRNGCRFCTLIVDSYGAERFKEIFLKHSLGMTGQVLGHVGLPSQKFWIECSNSAVFFQRPFDLCAVPDHPLPNIWNVNPPRNADCKEMFDRVHELLDQCIDHHDCGIIPDTELPSRVLDVSDNATSTVRLLVTVEGSATHGKYVALSYCRGVAQGLNTTSDTLDKMKVGIDLSIMPKTIQDAVLVTRGLGIRYLWVDALCILQGYDDSARLDFHREAARMERIYSNAFLTISATRGSDAGLFFTRCVAMPFCDGLGRSGKVNVVRYSKLRFGTEPIHRRAWTLQERLLSRRVLHYCNGHMVWECDNGLIKEDVMQGSVQKIIFSQEDRYRLPRNLSGKDWRMIVQIYSGRLLSVSSDKLPALAGIARRYHQLTGDRYVAGLWERELVVDLLWYRPNPQGTGLPPEYRAPTWSWASRDGRINFLFENGLQGFDSSEFVASVLESSVTLLATDEFGPVTDGKIVVQGPLALAKDVGIDFPSSTIGASGHTLYFDDGVEIFSAYGEHMSKIHCFLIAKPRECYGLMLLPAEDMPDHFFRLGMFWTYRSSLCPCWDGIPERTITIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQY3</accession>
    <name>A0A6A6NQY3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADH-ubiquinone oxidoreductase 9.5 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_292107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQY3"/>
    <dbReference type="OrthoDB" id="2093409at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22903">
        <property type="entry name" value="NI9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039961">
        <property type="entry name" value="Nuo9.5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="76" mass="8856" checksum="C9A43BC4B7B4FC42" modified="2020-06-17" version="1">MNRPPFWTQPIRFFRYTAHERPALFWSILVGCVGPVMIVTVPPLRHRFGDPTPERIPLTYPIPKGPRKIPEGFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR24</accession>
    <name>A0A6A6NR24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_115776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR24"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="376"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="378"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="480" mass="53771" checksum="DB2D3E8EB52E895B" modified="2020-06-17" version="1">MEYLTLRDNPRATVCASVRGGLPYAKQRVASPFPSTKRSQPTAERKAPCQQPAAMDRASMESLLGPGRPEYGGDNRASPRVTLSRGQERAQPDRQAQTLPAIDSNGTHPGAQRSQSSATVFHPGSSSCSHSQQYYPLHQHSRPSAVEPPFRPQLPEPQPNVLFSMASNGRVFSASNNARSQITPPRFTSTAQSDGNTSRNHSNGGQRLRQPSSDSYTPSVPLLRNHASVTEDSFNFHTYPVDESPTRRPSGNTSPTGSFSDSFPCSPMDDPQQYDKPQPHSRSLSPRDDQSLAKLPGACLPTRARDGPWRDMHSRNEPNLHHHREGLHHTTNRAAPQVRTEQPVMYSHTDSLDRSLVSSSLYNYPHSMCGPGEHFPSSRRRRGNLPKEATDILKQWFREHESNPYPTEEEKNRLVNITGLQAAQVSNWFINARRRMPQQNSRSDLKRRRSRSLSESRFIGNPDNNSLKEGELERGRKPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR74</accession>
    <name>A0A6A6NR74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isochorismatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_111457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR74"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="27"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="247" mass="26853" checksum="BDD7E9161A768A03" modified="2020-06-17" version="1">MASKKIQIRTAEPYAWPHDACFSPSTTAFIIIDMQRDFCEPGGYLSSQGYDISSTRAIIPALQALLQAFRTANFPIYHTREGHRPDLSTLPRRERYRSGVIPGSLPIGTHGPLGRLLVRGERGHAHIAELAPAEDGSEPVVDKPLRSAFAHTDLDLMLRVRGVKCLVIAGVTTDVCVKSTMTDANDHGYDCLLVGDACAAAEKGLHEAVLKSVAGEGGIFGAVAEWKDVVEVVKSWEQYEHETGNCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR78</accession>
    <name>A0A6A6NR78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_366633</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 6"/>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR78"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025483838" description="peptidylprolyl isomerase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="14649" checksum="8A53EFB331864D70" modified="2020-06-17" version="1">MQLPALRTLALLALPVLAAAIPENLGIEVTQEASCSRKTQKGDKIDVHYRGTLQSDGTEFDASYNRGTPLTFTIGGGMVINGWDEGLLDMCPGEKRKLTIPPELGYGDRGVGPIPGGATLVFDTELVNIHGVEKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSM0</accession>
    <name>A0A6A6NSM0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_352114</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSM0"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="19"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="57880" checksum="C0C85D3F903A3D3A" modified="2020-06-17" version="1">MSFLATWAKNFYHDKKAQVVLFSSTAIALYGYDQGMMSLINTNHDYLTTMGISETSSVVGVIVAVYYLGCSAGAVFFSWWADRWGRKKAIFLCLATASLGNLIMFTAGLGYSRGALAVMLLGRIIMGLGVGGVDSVIPVYSAELAADEARGKALAQEFQMNIFGLNMAFGINLGVTRSLGKWSQWAWRVPIIVMQAYPVILLAFIGDLPETPRWFVYHDRREDAAEAMEEIYGEAEGKRKCEELIRAHETAEEEPVSYLNMITPGHPQFHPTVITIMGQINQALTGYGAVSVYGPQIFELLGFGVHLAEYLTQANYISYFVLMSVAWILIDAVGRRKLLVGGSMCLTVSFLLLAIFGGMAMSSSRKVDITPMVPAVLGTIVLFIATGAFGIGWLATVWLIPTEIYPTTARAQAAAVSVVVWGFANFAITLLTPIWFNNLTYWIFLIFAVTNAFAGWWTYVYLPESGGRSFEENQQYFEDAKQAGTWNVRKVEMGKFKRFPYPSDTPQERTPLLQRVEDQLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSM9</accession>
    <name>A0A6A6NSM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSM9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7439" checksum="721712C915FB9633" modified="2020-06-17" version="1">MEKERVTFPPTHRAQVVQRSLLDAALLEVVLRRFDDPLEDLLVDGSNDSIRHDAGSLMPDVRGGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTC8</accession>
    <name>A0A6A6NTC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_76590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTC8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="20620" checksum="BC6299F182DCA813" modified="2020-06-17" version="1">MRCWQRLLPTLFDAEHRGTQAKDSFFQLSIAPSRFNAPLPRRLDRAIGLAANPVDSKPLLKRRSKRKPSTHQAKNFRTRSAHDKICTRCKLSAARDGWRQAATEGRERREASLKNTTKKLFASQLNMRTVAPLLRAHCRVALKVERMGSTSEMAEKWRKRRKMWTKKFLFGVDIDNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTZ3</accession>
    <name>A0A6A6NTZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_96645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTZ3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="15382" checksum="141E20E99A554559" modified="2020-06-17" version="1">MCLSLGHGMQGTAGADPCSTCLSFFSSCENRPARRGLAGQNTSCPILSASDIFVKSKLGGYSCIFGCVIACASLFSCSEHVGRVPVSGLVAHSGRSPTIDSHLGQTAFGRTVSCANAAMDSKGASIVPVLGNLSGTRLVKSGAHAKSVGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU78</accession>
    <name>A0A6A6NU78_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_307657</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2454992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU78"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="181"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="319" mass="33551" checksum="DA953FE27E69AD90" modified="2020-06-17" version="1">MSSSNPGTSGPYQYDNDAVEQDLIDPDDAALDDLDDPLQQPSTSDRTPLTGNIQSQASSSRSGGGGGGSSGGFGSQSYLTSRIPGEDRRAATNTIDESVWATLSRDLLAVWEKMRQVLWPKYLLGGMLTRGGGGMGGAAERGEAGGFGGGVGGMADAARNLMGRWPDADVVLQGAMSEGLRDWDLWGPLLFCLLLSLFLSRGAQDEQKSLVFSGVFAMVWIGEAVVTVQIKLLGGNISFFQSVCIIGYTLFPLVIASFLSAVSLPMIARIPVYIVLGAWSLAAGVSILGGSGVVRNRVGIAVYPLFVFYVALACLCFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUF7</accession>
    <name>A0A6A6NUF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_79477</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUF7"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000011">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000014">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="121"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="233"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="271"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="343" mass="39406" checksum="9F1F06A048AD4D70" modified="2020-06-17" version="1">MPSTRKKDKPWDTDDIDKWKINPFTPQDNAGGTFAEESSFATLFPKYREKYLREAWPLVTRSLAPHGIACTLDLVAGSMTVATTRKTYDPAAILKARDMIKLLARSVPAPQAVKMLDDGIACDIIKIRGLVRNRDRFVKRRQRILGPGGSTLKAIELLTETYILVQGNTVSVMGPYKGLKEVRRIVLDTMNNVHPIYAVKELMIKRELAKDPALANEDWSRFLPNFKKRTLSKRKKPLKVTDKSKKPYTPFPPPREKSKIDLQIESGEYFLSKEAKARKDRERREEASRAKRQEKMKEREKEFVPPKEPGVEKERKRKRKEGENGEEKKKKKKKSKANGEVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUN9</accession>
    <name>A0A6A6NUN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL lipase/acylhydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUN9"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="337" mass="38066" checksum="BFF00F396DDCF407" modified="2020-06-17" version="1">MHRRRDISSFDTLITFGDSYTDETRLGYFIDHQTAPPVGWDAPASDSTASGGYTWARYVADYSGARLYNYAVSGAVCSNDITPRWYSAIDAPFPAVAEYEVPAFLADSAYVESDGARFMSLEPDATVYAMWIGTNDLGNYAFIDDAQVPGTTIPDYVDCVYAQFDRLYDNGARFFVLMNNVPLQLAPMYAVLENGGTGPNRYWPDRSPDANVTETSYRMWEQVVLTNKEFQYRTPFEVMVANRYPGATIVNLDVYNLFMDMYNQPDIYFNSTGPANVTGYQNHCDLSGQNCYSLPDPDSFMWFDPLHKSEQSDRIIAQTFVEAVTGQSDYATYWESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUT7</accession>
    <name>A0A6A6NUT7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUT7"/>
    <dbReference type="OrthoDB" id="3915838at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025467325" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="18299" checksum="0BC8EE53519471FC" modified="2020-06-17" version="1">MVQLNYLTLGLLACLVSSAVSIPMPWPLSSLFPRQASGQQIRGVRDPIYHLYLQDLDGKPVLGPEESADTFDISGTIQSTTTGLYLTIGESDASYMPITWSEEGTTTAWGLEGDTIITTQSSSYGRQLNWVVCADETSGYYDIYLQTGADVPPGDCSNYQTLHLPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV04</accession>
    <name>A0A6A6NV04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_68455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV04"/>
    <dbReference type="OrthoDB" id="5426797at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF4">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="89" mass="10642" checksum="DE50836CE2BBBB1B" modified="2020-06-17" version="1">MIVLGIFDDALEMDFTSVEQIFQLRVDPRQQSMRLKWKKTWEERLIFWQAVPILDGIRTSHEEPLHYHSFLCHIQRLGFIAGMMKILNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV81</accession>
    <name>A0A6A6NV81_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">beta-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_70620</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV81"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000757">
        <property type="entry name" value="Beta-glucosidase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF5">
        <property type="entry name" value="BETA-GLUCOSIDASE M-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025395498" description="beta-glucosidase" evidence="14">
        <location>
            <begin position="21"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="15">
        <location>
            <begin position="691"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2455695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="776" mass="84370" checksum="F06ED0495A927EB7" modified="2020-06-17" version="1">MKSVLTAVVLLALYIPSSDGYTSWSYTNESEVPYYGLSPPVYPSPAGDGSSSPEWAAAYARAKDLVAQLTLEEKVNTTRGFDGPCVGNSGTVPRLGIESMCFADAPDGIRGQEFVSAFPAGIHVAATFDRQLMSAYGKAFGQEYRGKGINVALGPVAGPLGRVARGGRNWEGLSNDPYLAGAGMGEITRGMQLEGVISTPKHWLLNEQEFRRRPSEDYGEALSSNADDRTIHELYVFPFMNSFKENAGCLMCGYNRVNNSYNCQNSKLLNGILKTELGFEGFVVSDWNAQYAGVATTNAGLDIVMPDGGFWDGNLTEAVNNGSVAMDRVDDMVTRKLATFFYMGQDTNYPEASMFDYDQKHLPVNVQGNHGALIREIGAAGTVLVKNVNNTLPLKNPTFLSIYGYDATVKASPWENPSRYGGGYEVNYGWNTLNGTLITGGGSGSSAPPYVVSPFNAIQQRIARDNGILRWDFYSEQPSPAYVNSDACLVFINAYASESFDRTSLTDDFSDNLVKKVASMCHNTIVIVHSAGIRTVDAWIEHPNVTAVIFGLLPGQESGDSLADVLYGDVSPSGRLPFTVARAESDYGHLLNSTISYAAFPQDNFTEGLYIDYRHFDKYDIAPRFEFGFGLSYTTFSYADLSVSAAGSQQLSALPSPPLSRVPTGGHPALWATLFTVSVSLTNTGDVAAHEVPQLYLGIPSVDGDTPAQQLRGFDRVWLAAGESKTVEFELARRDLSVWDVEAQQWRLRGGTYKMWVGASSRDLRVSGEMEVSVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVE2</accession>
    <name>A0A6A6NVE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_365014</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVE2"/>
    <dbReference type="OrthoDB" id="5345625at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="363"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="265"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="525" mass="53499" checksum="6CED566615E8A03F" modified="2020-06-17" version="1">MQPSRHSPAKGPSSTAPQASPQAHRRPLGEVTPNTRRVSVAPAATGMAAAKGSPVKFAGTPGAPGSTKRVGSAVGAIAKENIDTADIGLPGATATAPAKMGMLSPALSQARGEQAVEDGREKALENSRESNASATDHYHHRHDLLTKLPSDLSTTDANTTPPSSAGSGAAQTATQRSFSSLINYEPESQSQPSSQQQQQQQQQQQGRTASDNAGVRSASPTPTASAGNEGADIKGTVEMLRLRLRVAMYKVQTNQTGVPFGQLEEFTNSGSPGASSSPRTVSPAANNNANGKQLATTSVPQPVDRAHAHARPRPFSVPDPAALSPTKHQPPTATSAAAAASQLTRTTAPAPKPLSLFLAAAPVLKPTPFSSRRVTWAADDEDARAGAGEDPGRRASRSPDAVVAFASSPPPPPPPPPPATMRGDAEDAMRDSAGSAAGGAAPPDADGGDEARGRARCGMGAERGASPLAAREAASLRTPVAGRRGGVGEAEEGEEAEEGGWEGLSSSVVRGKAASGLLELRRRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVL1</accession>
    <name>A0A6A6NVL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVL1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="61" mass="6923" checksum="D06D20C4783301EF" modified="2020-06-17" version="1">MRSSGSPLVRSDCPAATFFHISAVCFASKNKYEIDAEFISLHLCIHAHEHTRICSDMYTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW58</accession>
    <name>A0A6A6NW58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_386814</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW58"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="97"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="249" mass="27657" checksum="9F11D504CDBD0DCC" modified="2020-06-17" version="1">MAADFADFDLSQRRISSLTPEIFYIPNFISADEEAQLLGKIPPNRWIVLTHRRLQAHPSQLARNNTLLRAPLPPWLTDPVVPRFERLGIFSDTPHRAPNHVLLNEYKPGEGIMPHEDGLAYAGVVATVSLGSTLVLDIYSKRDGTRMKEPKDRSQNGPKVISRILQEPRSLLVTKGGAYADYLHGIAPVTQDTDLNPSTVANWSLLGNPTAFESGTSKRETRISLTYRDVLKVSDAASRILGKKNILVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWC6</accession>
    <name>A0A6A6NWC6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_288795</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWC6"/>
    <dbReference type="OrthoDB" id="3598281at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056024">
        <property type="entry name" value="DUF7605"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24564">
        <property type="entry name" value="DUF7605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin N-terminal" evidence="2">
        <location>
            <begin position="103"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7605" evidence="3">
        <location>
            <begin position="735"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1105" mass="124814" checksum="414236D6E202A572" modified="2020-06-17" version="1">MSIQEPSQLNKTSIASGRVNTKWTTRDGDEPFCPPFLENRYLHQLTSENDPGKLEASMSIASGLLTELKTTIQEYSQLSSDAGHWLQTIAETEKLNTRTRTIIGVVGNTGAGKSSVINAMLDEEFLVPTNCMRACTAVVTELSWNDSSDIDEKYRAEIEFIQVDEWEKELEILYKEMLDLNGQVSREAYDEDTEAGIAYSKIMAVYPQLTKEGIARTTPQQLMNRIRERHILGTTKRVRDSSPTRFYKQLQRYVDSKEKDHKKKDKPMEFWPLIKVVRTYIKADALSTGAVVVDLPGVHDSNAARANVASGYMKQCTGLWIVAPINRAVDDKAAKSLLGQTFKRQLKYDGTYSNVTFICSKTDDISITEAIDSLNLDDSVGKSYEELDHLEEDLYSLEQHLSELKESRQVYAGIYEDEDIRQETWENLLEDLKDGHAVYAPRDKKRKRSSDSDSKKAKKTRVSDKDSDDSFGGSESSESEHSDDSDDEEDPGQPLDEVTLRNTIEEIKGNKIRARNEKNALTPKINGAKDEIKQLKKKIGDRKSQISSVCIAERNRYSKGAIQQDFAAGIKELDQENAIEEDEEHFNPDDDIRDYDAVASSLPVFCVSSRAYQKLSGRMKKDPDVAGFTDLEDTEIPRLKARCKMLTESGRAANCRAFLNNLNQLLLSLRLWSSNSGSGANMSEDQKNLERNFVKKQLRRLETRLEHVTRKCLQEMRSNLEQNIWDRAAKPVEEACNKANPTSERWGMLRNGGLYWATYKAVCRRDGVFHGSGGLHDFNQQLLDPLTRGLAGGWERVFQRRLPQLLSSYTKAAFHELSVFHDAIERRGREHGLGVAEIGTLRTQLKIHEALLSQLAQKIVALIQEHQRDANREFVPVIARAMQPAYRICTEINGTGSYKRMKSEMESHVDNQRHSMFMKATDAVKDRLDDMWRIAEQHMSKGAEEVFMLMQRDYLNVLGGVNPQDSAMLSKTERDFRRHVSNQIEGADKLFRDIVGGEPTPEPEQEADMPDWDETGPDTPVKNEAHVKPELGELARDLLHSPDAADNAMGEAASVIKSERPASQSQEPFSNSVEQTQLSEGVVDRNANMSTSGTADEVVPEHMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI0</accession>
    <name>A0A6A6NWI0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">TATA-binding protein-associated factor mot1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Modifier of transcription 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NCT transcriptional regulatory complex subunit mot1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_365097</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box via its C-terminal ATPase activity. Both transcription activation and repression require its ATPase activity. Part of the NCT transcriptional regulatory complex that acts as a key regulator of ergosterol biosynthesis and the azole exporter cdr1B. The NCT complex binds the promoters of genes linked to azole susceptibility, and especially represses the expression of cdr1B transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms the NCT transcriptional regulatory complex with nctA and nctB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10252227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17999">
        <property type="entry name" value="DEXHc_Mot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000009">
        <property type="entry name" value="B-TFIID TATA-box-binding protein-associated factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000508">
        <property type="entry name" value="Probable helicase mot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000445">
        <property type="entry name" value="Related to MOT1-transcriptional accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000428">
        <property type="entry name" value="TATA-binding protein-associated factor 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044972">
        <property type="entry name" value="Mot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044078">
        <property type="entry name" value="Mot1_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022707">
        <property type="entry name" value="Mot1_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498:SF1">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12054">
        <property type="entry name" value="DUF3535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="1356"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="1719"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="189"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="274"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="733"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1702"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="1702"/>
            <end position="1714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00053370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00064550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00073046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00081280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00081329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2455864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1959" mass="215254" checksum="0AC9072530870029" modified="2020-06-17" version="1">MASSRLDRLVTLLETGSTQLIRNTAAQQLADVQKQHPDELFNLLTRVIPYLRSKSWDTRIAAAKAVGGIVENAEKFDPNAEDPPSIKSENGDGGATFDGSAAVKSEVKTEDGVAVPPNEEQFTLETLDVALILKQGKKLLGSVGKEYDYMLANLDPAERLAHQKKSLTARLGLGGEYIEEDLVTEKDFALPTPKHSNPMPTPGLHKLDTSISRTNSAPTAAAESATSPHEQPAQTPADENGGLSKRQLNMLKRKNKKEFKNQATKVRVIDLAGRRSSVASGGSSDQLPAPQSAQPQPHAIKQESGGEGNDVQDYFSLDRPNGDDDAKVVSEFKGVPPPEKSTFQSEEEESGLEWPYERLCDYLSVELFDPHWEVRHGAAMGLREVVRVHGAGAGRIKGRSRAENDVLNKRWLEDLACRLCCVFMLDRFGDYISDNVVAPIRETAGQTLGVVLQHMPAESVKAVYHILYRLVMQLDLGDAKPAWQACHGGMIGLRYLVAVRSDLLLHDRVLMDGVLNAVMKGLSDYDDDVRAMSAATLIPVAREFVNLRPSALNSLIHIVWDCLSSLSDDLSASTGSVMDLLAKLCSFPEVLDAMKKNAAMDQEQSFANLVPRLFYFLRHTITSVRSAVLRALLTFLDIEGEGTKGWINGKALRLIYQNVLVERNEAVAKLSLKVYSTLLTTLSTGGPNAVAVELGPHIDALVQLTVHPIGVSRHPIPMDGSLFIKPSGQTYALPAQPGRKASSPTHTTVSEKSGRGRRKSDKKEKEAVQTPTTHNVDAHMMQGDVDLVGMDVMLRSKMLTAEALGKTIASWPSPHRMETFGVRLVHYMKSPYSTTQLTASMVAEEYAKATSDKDDTAVVFAQTLHRLVEDERPAYYSDLTSYLQVVRAQCQSLLSTFRETAHVAPSKLPTPAVIVQGEPEASQFAFGMADATKIVEVTYEQLKKQLTPAQRIASSKPLADARTDVITAMEEAITVKDQRDVRIRAAAAAAIVALRDIPKKPALTIKGLMDSVKKEENEELQKRSAAAVAVLVDHLSAAGKHAVIDKVVGNLVKFCCMETAETPEFHPNAHMTIGILSLKKEEDVRDPADAARFEAEIKAARITRRGAKEALEQLVVGFGSDVFGRVPILRRLIEAPIQRTFAAELPADIADPNTTLGQEAVDGMSTLRALVAKFDPGLHDFVLELLPLVAKGLQSKLAVLRYAAAKCFATVCSVLTVQGITMLVEQVLPAINNANDVHCRQGAIECVYHLIHVMEDGILPYVIFLIVPVLGRMSDSDNDVRLIATTTFATLVKLVPLEAGIPDPPGLSEELLKGRDRERKFMSQMLDAKKVEPFEIPVAIKAELRSYQQEGVNWLAFLNRYHLHGILCDDMGLGKTLQTLCIVASDHHMRAEEFARTHSPDVRRLPSLIVCPPTLSGHWQQEIRQYAPFITAVAYVGAPAERVKYRPQLTQADIVITSYDICRNDIDFLAPLNWNYCVLDEGHLIKNPKAKTTLAVKRLASNHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKVFHDRFSKPIAASRFAKSSSKDQEAGALAIEALHKQVLPFLLRRLKEEVLNDLPPKIIQNYYCDLSDLQKRLFESFSKKEGKSIAEKATSANDRESKQHIFQALQYMRKLCNSPAFVVKPEHRDYGDVQQYLGARGSSLQSAEHAPKLGALRDLLIDCGIGTADVGANGGGNGNNGSGSSGEVDIPSAGEAVSQHRALIFCQMKEMLDMVQNQVLQRMLPSVQYMRLDGSVEATRRQEIVNQFNSDPSYDVLLLTTSVGGLGLNLTGADTVIFVEHDWNPQKDMQAMDRAHRIGQRKVVNVYRIVTRGTLEEKILNLQRFKIDVASTVVNQQNAGLGTMETDQILDLFNFSADEAATGGLVAPPPGAQQQGGEQKISEDDAVDATGAVREAGKRGFLDELGDLWDERQYEEEYNLDSFLASMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWJ4</accession>
    <name>A0A6A6NWJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_57166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWJ4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="23550" checksum="70E2EF9D42051946" modified="2020-06-17" version="1">MTNLASLRVSSRVDAQSQTFCSLFFRLTIRRSYDAARNARIGNAIVDFGRKAQDFRRDRNMGIHCSGAVCKEDPRMNSGAVWLVARVPWVPLGLCAMLSPRARPRRHKLGRGRLAKFSRSWEGLAWQIALHLSSPALNNSTFFIVPRAMSTYPLCCHSCGPGGGHYILPRAPRYPTMRATAKLLWISGDLNTSVGSTPFIDTSGDLHDAFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWP9</accession>
    <name>A0A6A6NWP9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM3</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_288122</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWP9"/>
    <dbReference type="OrthoDB" id="1882346at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17754">
        <property type="entry name" value="MCM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000008">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008046">
        <property type="entry name" value="Mcm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056575">
        <property type="entry name" value="WH_MCM3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF46">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23191">
        <property type="entry name" value="WHD_MCM3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01659">
        <property type="entry name" value="MCMPROTEIN3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="296"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="509"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="674"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="526"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="755"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="776"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2456151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="879" mass="96420" checksum="D4FA9587FF312639" modified="2020-06-17" version="1">MDERLRDEEFQNRVRQAQEFLDPSSYRAEVELMLNRGLRRLTVSLDEIREHDRDMAEGLLNDPFEFSLAFDFALKKIVETVVSQTARETSEDDVYYCAFVGSFGEFTCNPRTLNSSHLNHMVSLEGIVTKCSLVRPKVVKSVHFCEKTRNFHYREYRDQTSSANKPASTSVYPTEDDEGNPLVTEYGYSVYRDHQTISIQEMPERAPAGQLPRSVDVIMDDDLVDRVKPGDRIQLVGIYRSLGNRNTSSGSSTFRTLILANNVILLSSKSGGGIAQATITDTDIRNINKISKQKRIFDLLSQSLAPSIYGHDYIKKAILLMLLGGMEKNLDNGTHLRGDINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTSDKETGERRLEAGAMVLGDRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPIYGQYDTHKDPHRNIALPDSLLSRFDLLFVVTDDIEDARDRLVSEHVLRMHRYREPGSEEGAPVRDGGAAQTLSVGTENNADGSGDANKPTEVYEKFNVMLHAGVNVTVKRGSSRKVEVLSIPFIKKYIQYAKSRIRPVLTKGAADHIVSVYSALRNDELEGNQRRTAPMTARTLETLIRLATAHAKSRLSNRVETKDAEVAEEILRFALFKEVVSTDRRKRRKTAGLDAMSTDEDSSSESSDDEDNSGRYRGTGTPRHRPRPGATPRTTRSQRTARRHGTPASGAAEDDDDDDQLYNVTPQTRRPTQATTTAQAGTASQLSPASSRPASQLLASQTESSGAAATQSQSQSRWAATHGVDPGRVAAFRAALGQIINSQLFAADAADAEPVVAAVNGRLGGGAAEFGPDEGRRALECLSDQNLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWU4</accession>
    <name>A0A6A6NWU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L4-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_65137</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWU4"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="280"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="372" mass="40238" checksum="F9D011B2709D53EC" modified="2020-06-17" version="1">MTTRPTVSILSPDGSASGNSHPLPEVFKAPIRPDIVQAVHTGMAKNRRQPYAVSEKAGHQTSAESWGTGRAVARIPRVSGGGTHRAGQAAFGNQCRSGRMFAPTKVWRKWHQKLNLNQKRFATASALAASSNAALLMARGHRVSTVPEVPLVVSSTAFAGAAITKTSAAVALLKAVGAGPDVDKVKKSRKTRAGKGKMRGRRHKQRRGPLVVYSPAEDGKELVRAFRNLPGVETCDVYALNLLQLAPGGHLGRFVVWTSAAFAALDTVYGSATEASALKKDFLLPSPLVRQPDLAKLINSSEVQSVLRPVKGGAITKRPMVQKKNPLRNRQILLRLNPYAGQYSKDKLGQQKKDEKEKIRATDEIMDLMHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX73</accession>
    <name>A0A6A6NX73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein phosphatase 1 regulatory subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_346865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX73"/>
    <dbReference type="OrthoDB" id="266138at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000446">
        <property type="entry name" value="Protein phosphatase 1 regulatory subunit SDS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47342" checksum="355CB773C150255D" modified="2020-06-17" version="1">MSAPADDASASGPPLPPPADHEHVTLVPTRPPAEDGAGGAAERTTATMSSPVRSKSGWDGKLRVERKKEVRVGGAEGGEDDREEEDDDEEDEDEEEEEDGEGHGGTRAAREARVERGEDVPGEEIAADEDLLEGEDEDTDEIDLVHCRISSLPALKLERFTKCERLCLRQNIITTINFPSSLGRTLKDLDLYDNLIAHIKGLDDLTELTSLDLSFNKIKHIKRVNHLKKLRDLYFVQNKIQTIEGLEGLSELRNLELAANRIRTIENLDTLTALEQLWLGKNKITQLQGLSTLTNLKILSIQSNRLTSIVNLSALAALEELHISHNAIASLAGLESNTNIRVLDITANPVTSLAGLGPLKKLEELWASYCKLEDFAEVEDVLRDKEELDTVYFEGNPLQTRQPALYRNKVRLALPQVKQIDATFVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXE9</accession>
    <name>A0A6A6NXE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_305427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXE9"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080042">
        <property type="term" value="F:ADP-glucose pyrophosphohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080041">
        <property type="term" value="F:ADP-ribose pyrophosphohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03424">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5_UGPPase_Nudt14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF18">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="210"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="412" mass="44296" checksum="251C3002D28ACC3C" modified="2020-06-17" version="1">MWIILKPRASTLRSQASEGKSEGSNMKPWRVLRVTTNPTLSSSSPVPLHNQPLLFRYTPHPAVNVKTAHHTPSSPPTSRLYQSSAHLHPANSCRLLTTKGPSTTASMSTSSPTNASPLPSIPLTIPSHLSLTPTDLHSFAPYTSWLRTLTHSLSLQHASPTHPFHAAPYALRHVTVQAVDRFGGGRIGFVKLVAEVANDAGEKLPGAVFLRGGSVAMMLVLSAEDGGDGERGGGRPRRHAPRPDDDKYVLLTVQPRVAAGSLAFAELPAGMLDGGGNFAGAAAREIEEETGLVVRAEELVDMTALALAPAPGGPGGPEDALEREQEQERLRPAMYPSPGACDEFMPVFLHERSVPRAALEEWAGKLTGLREHGEKITVKVVRLAELWREGARDGKTLAAWGLYEGLRREGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYM8</accession>
    <name>A0A6A6NYM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">N-terminal domain of CBF1 interacting co-repressor CIR-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_286964</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYM8"/>
    <dbReference type="OrthoDB" id="21123at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="8">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="12848" checksum="7F91B1B4C90D3D25" modified="2020-06-17" version="1" fragment="single">MGGDLNLKKSWHPQLMKNQRRVWEEEKKALEERKRIDQMMKERAEERAIQELQQMQEAAGGKKRMNRVDWMYNTPAAGQAGTTEEMEGYLLGKRRIDNLLKDNESAKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYQ1</accession>
    <name>A0A6A6NYQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_345683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1883964at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="594"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="826"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="897"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1004"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1194"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1742"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1394"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1709"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="335"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="829"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1050"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1219"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1240"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1751"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1770"/>
            <end position="1782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1782" mass="193057" checksum="AF8293EA5F2C130B" modified="2020-06-17" version="1">MQQPYVAQAQGQGQPYGGPASYAGQQTAYPGAPTAFAPGAASPLQQSHQQPSVAAYNPSAYGPMPGSQSQYQKLQHQQYQEHQQHQPYQQHQLYQQQPYQEQQPQQQQAPPPVPPRIPTASPQASAQSVPQQIQPPDQPAPPGQQPQTSQAPVASSLPPEYQQQVRHNQQGWPQHPPYSNQAPSHHYDPNAQSHQNHVQQGGTVHYDNSAPPPSSQTPGGFYFPPSKPPAVPPKAPVNYGAQGSADAPGRVGASQSPAASVDAFSPNEQQPAYVPPSLSGQGIASYMPSNTNPLPGVYVPPPPDSVPAWSQAQHQPMQGSKFKYTRPIVYLNHSTQGQVHGHPTQQPGQGAPGQYQQQSQQSQQAQQPQQVQQPSHYDQPVQHPAPPQQSFTQSAQVQPEQFATHQSRLPQAHQPLQFPQQSDMAAQQAGHCDNWSQGYHRQSTYGAQQTQHPQEQEEWGTQPQNNVSSNLSQGQQQPSSMAHTNQEHSSDQQQSVQVPPSNLHSPRSETRHSYNALPGHMQGYSQPQSFEENPVSPIQHRPSVSPKQSSGASPVHRKQSPASRNGGNIPPSISAVQDLNPSSLARSNTLTSASALGFGGPSDWEHFGTSTEEVDDTDKYGSQNKNDGAPSSPQQLDSTELVSKSSPDSSKIRTESVAISEPSEWPTPPAQASLQMHGTVSQSGQGWNRNPRWDTFAPTPPLGCASVHNLTDSIVSEDGVSDKRSQTPQRIQDVTTQDVAQSSQRGNTSSSFVVDESTIAQRAQTSTEPPEHSLQSVRHWTPPPTSNTTIIDDGVVSTQIPAQQSQSRPISPSSISNVVFTVDDGVVPQRSNSPAAQKEQQLSRPTSTVSAQNAPTDASESHVSGGMQADNGGHVAPRVLRSTRPTSQVAIEGTQPVHGLPEIPTKTSKIQSPPGEARVQGASEPERTIRDNPALASVAGPVQSMAAQPQRTVQARDLIPDLDPWYISSLERYISMLRQESQAFTLEGKISVFSEFVKAESGMRGIEYPSRPPPPPPTTEHSIQTDPALSEPVKQDTSPGCLGKARSMKPLSQRQSLEISTATSTSTPTNEGQYSPGGRPIVIRGQSYSPGGRPMMPRTQSNTQNISGATQEHNQTSHVSSPVISRTSSWKQYNHQETASPSLPVLARSTEEIHALQDPNPTGPGYDRTNSSSGYKPYRNATGSTSIAPAKFSGLGAAADGQSPQPTVLTPTSSTDDDSATRELAPETEKTVYKPYVPPQQESSISDAGTTSLAQASPRSSISFPGGKSKRHRPHAEIFLGDEPNRTEESKANPVASIDGLAGPKLEDPLSPPPLQISKASNPPALAEDNKLSTHTAAFEHLHELSSILSEHITDAAQFPLSGHPLLAHLADILRAHPQNFDFMSSLAAAHDSKASLRRRQLQAERERRQSENEVRTDELYNNQEIGYGDISTLENEFREKERKLKVLEDRDEYELYVKDVFSPIYHRLQSEIGALMEGVVGAERAVIGAAVGLSGLRVKPQVQSSSSTTADLSPYPLVPALGALADLHAAVEERHARVAAAITERDRRYKRTEIGPLYEAGDIAQMRNVEKHFEVAERSTALKAAQDRDGRVRRLVNVVDEAVVRGVKAGEEATDEVLEILRKIQADVHKDGHGWASMNEDERAKKDAVLSQARLVLSGLAATNQELMCAFHKVETTLNDADYEIGVTKARLDGADAAVFDKLMAKKAAEDKKLAEDLSKRINIVEEEKVEFEELLGQLMDSSNSGGVKQESKYSGGRDQEDMNGLLKKALEEAKRRNGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYU3</accession>
    <name>A0A6A6NYU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS multidrug transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_286914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYU3"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="66"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="568" mass="60039" checksum="65DF9BD07C1E71F4" modified="2020-06-17" version="1">MDSTAGSLAVPGTGYNTASVTPSDLSINEEKEKMDEARQAEQEPKPEADQENQEEEYPKALKLIVILVALALSIFLVALDMTIVATAIPRITDEFQSLDQVGWYGSAFFLTIASFQSTWGKAYKYFPLKWAYLQAIFWFEVGSLICAVAQDSTTLIVGRAIAGAGGAGLASGAYTIIAFSAPPKQTGALTGLLGAVYAVASVIGPLLGGVFTDNLTWRWCFYINLPIGGLSAAIILALFQTPKAAKPVQATWKEKILQMDPAGTFLLMAAIVCLILSLQWGGVTKSWGDAEVIGTLVGFVLILAVFVGVEIYLDERALLVPRLLKNKTVAFLNVFQFFNSGTFLLLLYYLPIYFQVVSGVSAADSGIRNLPYILGIALLTIVSGGVITVTGHYIPMLVVGAVLATIGSGLIYTLDAGTPSSEWIGYQALSGIGIGLGIQVPIIVGQAVVDAVDVSSATAIIIFFQTLSGAIFVSVGQSLFANQLVESIPENAPGVNPGLVVATGATELRDVFPSDVLPGVIRSYMDGLKDAYALGIAMAGVAVVTSVAMVFFDRRNLSDRKGAMPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYV5</accession>
    <name>A0A6A6NYV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_41360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYV5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="21692" checksum="1D3378C30695C84A" modified="2020-06-17" version="1">MEPTQKCSPECTGGQTGLGARGAADERTCSFHAAHCQFAQQHIEQINAPSRTSGLDEHSRGSGSQGDAHGQAPASRRSRRVEHAGHPPGLGSGQVDGNSHPRSSSTPFTNGLTNQHYQHSAASCTLVAGSQGHSSPSHTATNANNVVSSTAGFLTTNQQRPAGGNVDHATLALTTFLVSKGPWSEYECHDLQAVFDMVTQFPRRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYY8</accession>
    <name>A0A6A6NYY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SMB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_415537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYY8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025330160" description="SMB domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="63361" checksum="0C7E7862EEE29F33" modified="2020-06-17" version="1" fragment="single">MRCYSLVNVLLGSVFTLEALAAPIPALNGTGASKPEGERKEFPKILHPAEHRPGDPPTPDNAFTLYRHPYDLHDNGKPIRPPTRLPPASPLKHQDHALADGALPDHDKTFTNVDKAGNILHDQQSRSHHGAVSVHHPCPYGPTANNDASLAACSRLTVVSVPVEQRPSHGKKDHGLLPRNPHIDETSIELADDTNKPHPDLYAPPSIQTDKRQNVTNESPAAPHGSVDFSENRNATMWQNRSLPYNHTEDQHTLNLGRRSEAVDETDSSITHAHDDPKNVHFHLPFLDFSFSGDDRKAKQRRDTSGFAAGSGLANLDSGAGNGLNHTHLDQTATEEPQHGPYTASSYNRPPTPAPEHKNMWYPGWPGPKFTHWPPPEDPQHPRHTTPPERKNLWYPGWPGPKFPSGLPHPPKTWRRMLPEPELGREPHEVQGVPDHRLAGNAPDLDNFSDLPKGADPDEKPAKQPETSRVARDAGADADADTTNSPLLGPDLTERGTPPPPGANLARPPWPTQHVPEIGRYKGEHAYKGCRTRHCCGAKCCGSKCCYSGCCRDDGCCRCDDDGCCDRDYGCCDDGKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ28</accession>
    <name>A0A6A6NZ28_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_344621</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS33 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ28"/>
    <dbReference type="OrthoDB" id="2257454at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013219">
        <property type="entry name" value="Ribosomal_mS33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08293">
        <property type="entry name" value="MRP-S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="102" mass="11880" checksum="571AF7397924F532" modified="2020-06-17" version="1">MAVPRGRILDLAKVQCRIFNTTFNPDGLRTGNKILRQRLKGASIADYYPRRGPTTRDLARLYPGLETYNDYEEERFEHIQITKSRGKGSPPKKREPNQFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZB6</accession>
    <name>A0A6A6NZB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZB6"/>
    <dbReference type="OrthoDB" id="4232400at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="30935" checksum="C638DA3C461C2314" modified="2020-06-17" version="1">MYSGWWYGYNGNHVPQGSYPSRSYPSRSYPSRSYPSASFARPHSSTAAGSPAPSNKDRSRCSHSEYYSSSRSNSKGYDSKYNIVKQGWGSFPNYQHSMGLKMTPEDLEGGNRILDEMVYRDTYGGRNSKGDERAFVNHRNTGSAGTGMIGGYSQSDISRRTNFELGREEEHHEDAYPNDTYSDSEHASCGSPREGFGFGRWADDDYHENNEKFVGCGGGGDGVVIVSSGAKEENDDVHQQEEGDEDEDDEEEEYDDDYSDGDYGGDDDYGGDDDYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P076</accession>
    <name>A0A6A6P076_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_286099</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P076"/>
    <dbReference type="OrthoDB" id="447729at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000005">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000001">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="entry name" value="Imidazole glycerol phosphate dehydratase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133:SF2">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="24060" checksum="7CD98226D320FA9C" modified="2020-06-17" version="1">MAERTRFATVSRDTNETKIELCLNLDGGVLDGAKSNGGSKAAQGHATQASKAQHIDIDTGIGFLDHMIHALAKHAGWSLYLRCHGDLHIDDHHSSEDTFIALGTAFKQALGGTAGLARFGHAYCPLDEALSRAVVDLSNRPFSVISLDLRREKIGDLSTEMLPHCLQSFAQAAALTLHVDCLRGENDHHRAESAFKALAVAIRTATAPIKGREGEVPSTKGVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0M0</accession>
    <name>A0A6A6P0M0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_270091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0M0"/>
    <dbReference type="OrthoDB" id="5284712at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF3">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="15"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="32879" checksum="562E63C3B771A294" modified="2020-06-17" version="1" fragment="single">MKIPQSYVQKCKVVAHVFQLLFIFIGFCLTIAVFTKGGETGGPSKYYFALCFLTIPGVIYLIMTPMWSRALRFANAYAFVAVDVLYTIFWFAAFIAVALWNSSGIRNGAKDRDLDEDAGNCTTFKYGSESRCNVSKAAVGIGVVIFIFFLLTAAISSYYLVQFRKHGHMPYQRGPSSPVPAPLEDGPKDVWSASTHDLSRSAPHDDALSDSDESDSGHGPSAAGGPAGPDDDEYALLPQQQQRGRARGASDVTHTEEGAHPGVRRDTFPRPAAGGYGDGGQGAEYSPGAGYSAPSALSPGGYDDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0M6</accession>
    <name>A0A6A6P0M6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_343660</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0M6"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="51"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="148"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="253"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="351" mass="37927" checksum="74F18A0B8BB9D83F" modified="2020-06-17" version="1">MSSRAPANPPAQEHAAPLARVSGLSTMDAARGNASPAPPTKVDKLRNTVSQPVFASFLAGGVAGAVSRTVVSPLERLKILFQVQSVGRDAYKMSVGKALAKMWREEGWRGFLAGNGTNCIRIVPYSAVQFGAYNFYKRFFEETPGAPLGAYQRLVCGGCAGITSVTFTYPLDIVRTRLSIQSASFKELGEHARKQLPGMWGLMFSMYKNEGGFFALYRGILPTVAGVAPYVGLNFMVYETMRRIVTPEGQQNPGTLGKLGAGAVSGAVAQTFTYPFDVLRRRFQINTMSGMGYKYTSISGAIAQIWTQEGVKGFYKGIAPNLLKVAPSMAASWASFELTRDLLTGLARPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0S0</accession>
    <name>A0A6A6P0S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">eIF-2-alpha kinase activator GCN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_344190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5148094at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904688">
        <property type="term" value="P:regulation of cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000090">
        <property type="entry name" value="eIF-2-alpha kinase activator GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022716">
        <property type="entry name" value="Gcn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056809">
        <property type="entry name" value="HEAT_GCN1_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12074">
        <property type="entry name" value="Gcn1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25801">
        <property type="entry name" value="HEAT_GCN1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24916">
        <property type="entry name" value="HEAT_GCN1_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="1349"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1526"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1986"/>
            <end position="2023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2643"/>
            <end position="2665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00072275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2680" mass="291223" checksum="EA190487E883C1F1" modified="2020-06-17" version="1">MTESNTGASRSLDRDSLRQRLFTSSTKTRIAELHSLHYGIDHEEIPLDSIVLVLELLFETYPFYVDRPSRRAVQQCLEAACANPNSEKLFPKFLSGLETECAKTNIAPSNAFALCEWCSTFLQQFAPKPEFWKKWGLQVVQAYAGALERCIGTEARPSVKHSALVVARRGLRKVFKSEEIGTNAVASTVKALTTKPPNPSAKNAVFLGVIAGVCARIPSRRPTLAAQKGYYYSFYIRELLSSKTILPGHIANAFHDFFEAFTTLEDLQKEVIPSLEKAMLRAPEVVLNNLVAPMVYSLPPGMDLSEVLSKNLLKPLLSNVKSTNSGIRNGVAETFEAVASKCADEQILGKVVDEILNPLKQSKVPAAEGKVLHSQMISNLRGSITLAKKVPSGLAQVALKESNEAALAAETNALSKHTAYALANGIQIESSVAQAFHKGLADKRVPIRRLWALRAGDLLWNISADDFERSDVLDFAIGCLKAMTDSWNETKKNPVQAVQSGLVPVALILTALGLSKLSSVMNSKMSETLSKFAIAKNALIAEPKPSFLLNYRIYSKLTTEDDLVWFLRALSGAASEMSTMGKKSRTSDAVAQAYLYILSAPGLPPVVRRTVIGDLATTYVQNPEFFGAVMISAMWEWQHHIETNEKDTAAIASKAGSSGLGLALQSIWSRPSGDASVNGGVGHAILEAQLIDLLVLARPELIPRSSWIDLCLRTGIDPGGLVKTKSKECLGRVIEATDENWQYASDSVRRAAYKAAADLAFVAPDTMVPLLVDQIKDDLDPDQLETIGPTEAAIFRTPEGTAYVDVLSQKGPASSVHKSSKDYDTLKWEAELRAQLAAKKGQSRKLTADEQAKVNAQLAKEKEIRRQVAIIEQKLARGIGIIESLATGPPTDAGIWFGHAVSLLLEVIKGGAALVIGDRAAMAFLALADLISPRLGVSKPFVGVATLRGLGNSPLRPEMEVEALGDLVTRILYRLRFMAEQRPFDNLTVTYVLPFLFLVLEKGGIGKSVGDEADEQILLSMEYLTFHTDSFASRRLPRAGVLSTLISSMRKYNQHYKILKDCLIDSCRSIAPEATDDELAILVGGCIVPEVSVRTAVLQSIDAEIDLIQDYYEEVWLACHDDVEENVELARTIWEENGLHLNKDTPTTLLPHLTSKNRQLRRAAARSLAEVISTFPDLFHAVLARLEDTYRDKAKPKALEKEDFGLQRKKDVPDPWEARSGIALALKEMSSAFTEDELVPFVKFLIQDGPLGDRNSFVREEMIDAATTIIALKGAAKVEELMGLFENALRGPDKGIEALDLVNEAVVILYGALARHLKSGDSRVPKVVQRLMDTLSTPSETVQYAVAECLPPLIQTSIQETPNYVQRMMVDLLQSKKYATKRGAAYGLAGIVRGKGIVVLREYRIMSTLKAASENKKDVNERVGAFLAYELLSLILGKLFEPYVIQVVPQLLSGFGDSSADVREACLDAAKTCFSSLSSYGVKQILPTLLEGLDDQQWRSKKGACDLLGAMAYLDPQQLAMSLPDIIPPLTTVLNDSHKEVRASANRSLQRFGEVISNPEIKGVVNILLKALSDPTKYTEDALDSLIKVSFVHYLDAPSLALVVRILERGLGDRSATKRKAAQIIGSLAHLTERKDLVAHLPILVAGLKVAIVDPVPATRATASKALGSTIEKLGEDTLPDLIPSLMTTLKSDAGAGDRLGSAQALSEVLAGLGTSRLEETLPSILQNVSSSKASVREGFMSLFIFLPACFGNSFANYLSKIIPPILAGLADDVESIRETALRAGRLLVKNFATRAIDLLLPELERGLADDSHRIRLSSVELVGDLLFNLTGISAKAEQDEAEEAANEAGSSLLEVLGEERRNKVLSALYICRCDTSGLVRSAAVNVWKALVATPRTLRELVPTLTQLIIRRLASSNMEQKLIAGNALGELIRKAGEGVLATLLPTLEEGLQISTDTDAREGICIALREVISSSSPEALEDYEKTLISVVRSALVDHDENVREAAAEAFDALQKALGKKAIDQVLPYLLNLLRSESDAESALSALLTLLTDNTRSNIILPNLLPTLLTTPMTAFNARAIASLAEVAGSAMTRRLPNIINSLMDNIVACKDPELKGELDASLDTVLLSVDEYDGLNTAMSVMITLMKNDDHHRRAAVDLHMAHFVARAELDYSRYHADLVRNLLISFADSDLEVVKAAWTALSELTKRLKKEEMESLVIPTRQVLQQVGVAGSNLPGFNLPKGINAVLPIFLQGLMNGTAEQRTQAALAISDIIDRTSGDSLKPFVTQITGPLIRVVSERSVEVKAAILFTLNNILEKIPTFLKPFLPQLQRTFAKSLADTSSELLRSRAAKALGTLITLTPRIDPLIAELVTGSKTADTGVKNAMLKALYEVVSKAGANMNEASRSAILGLIDGDLGEGNDSTEITNARLLGAMVKSLPLEVSTSLIKSRVLTTSFNKPSVFALNSILLESPETLTSNFVEETSSIICQGIGHSHPVIADNCILAAGKLLLSPTGPSSYESTRPLIEALAPVIAPGQPTDTRRLALVVTRTVARHSHELVRPHLPTIVPPVFASVRDMIIPVKLSAEAAFLELFDVVEQDTVVFEKFLAGLGGDVLSAGQKRSMQDYFKRVVLRLAAQARERREAEGGAGGLGLSSDEREDEREVWSVGKVELNEVGAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1M6</accession>
    <name>A0A6A6P1M6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_30190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1M6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="132" mass="13945" checksum="E9B9F40C676CCA15" modified="2020-06-17" version="1">MIVCRVCACSFSWLSRGAILINRATVPPAPRMMTSAGGTLTSQDAFFHLMFSTSTISLSLISDRSVSLSQMTVSTPQRAEARLSIQPSAASAASAAYYVRPHPPRGLRASRAANGANELSCQALTRATVGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1W7</accession>
    <name>A0A6A6P1W7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycolate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_320020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1W7"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF114">
        <property type="entry name" value="ARYL-ALCOHOL OXIDASE VANILLYL-ALCOHOL OXIDASE (AFU_ORTHOLOGUE AFUA_3G09500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="81"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="64631" checksum="622378B322EBDB6D" modified="2020-06-17" version="1">MASTKMPTRYADLEYQRTHRQLFGNSVTRPVEPVLPPGVSQAEFDRAIDEYVGVLGKDGVFTGKALEEYIDPYELWEAEGKRRVPSAAVCPTSVEELQGVLKVSNKYKIPVWTFSLGKNLGYGGPAPRLNGSVALDLHRMNKIIEVNEKYSYAVVEPGVTFTELYKYCAKNKLKVWPSVPSLGWGSVIGNTLDRGTGFTPTATHHQHICGLEAVLPDGDVVRTGQFAVSNSPSAHLSKFTFGPSIEGLFLQSSLGVVTKMGIWLHPQPQAYMSCVFDMPEFEDVATIVDVFGALRRDGLLPSTVYVSNIVEWTAMLGRRDELWPHKSPIPDWKLRELGEKIDLGYWSAKFGLYGPKAVIQAHFDELKRIVAEKAPTGRLRGDVFEGKDGKLLEATDIPEEHGGFFVGVPSLWSLPMVGYRLPKQGGGGVGAHIDYSPIVPSSGATVLEWVKTAKKICEKENFDLFCDFFMHERHVIFVNMMTFDKTNPEHRRAVETIFHNLFKEGRKRGFSKYRSHVNYMDLVADLYDFNNHAYRRFVEKIKDSLDPNGILSPGKQGIWPRRFRDQNREAIKSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1X7</accession>
    <name>A0A6A6P1X7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1X7"/>
    <dbReference type="OrthoDB" id="3941231at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="60" mass="6596" checksum="D1970593AB48FD9A" modified="2020-06-17" version="1">MSNPSSSLPTPRRGHGRMSSADERRRVAVPRRSTKGPLDSDVDEYAPPPARRPRSAQAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1X9</accession>
    <name>A0A6A6P1X9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_343261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1X9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025457649" description="Secreted peptide" evidence="2">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="9716" checksum="71362ED69A4F341E" modified="2020-06-17" version="1">MLLLLWRVRVLAAAAAAAAAAAAAARCGTVLSPTETGCSHRSSIEEAETACVISRLLVVLGLPLLPISSLCVLFSLFCFFLLVLGESTLAIGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2R2</accession>
    <name>A0A6A6P2R2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L34Ae</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_342122</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2R2"/>
    <dbReference type="OrthoDB" id="277449at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="12984" checksum="FB5E115E0533D488" modified="2020-06-17" version="1">MPSNRLTYRKRQSYNTNSNKVRVIKTPGGELRYLYIKKKPSAPKCGDCGIKLPGIPARRPREYATMSKPKKTVQRAYGGSRCANCVKDRVVRAFLIEEQKIVKKVLKESQKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2U5</accession>
    <name>A0A6A6P2U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_342242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2U5"/>
    <dbReference type="OrthoDB" id="10017208at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF31">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="382" mass="42670" checksum="15F3FE963D1A63C5" modified="2020-06-17" version="1">MPVSDRGWSLAIWMVVFTILTSLTMGLRFVALRVQRRSFRVDDYLIIGAFVNLIVLEVTSWWAIANGLGAPVMTLTPYQASVQLKLLLSAGMTWTFATVLCKLAVLWMYTHIFTVRPFKIAAYVTMGFVTSYAIIFVPIFFTHCIPIEASWSVDPVVQATQCRPIKRQEYASVSINMALDLAVVLLPLPVIWKLQIPTRKKIFVSFMFSLGLIIVAIMAWRIQSTVAASNQPDWNIALYTTALQSHLEVWLGIIAANLPTLAPLFSRFIKPTMKSYFNNFKWSSNNGGGSGGDGGKQYRNSHNMAIRTFGSGGPDLKAERFNRLAGSSGDFSDDLMDRYNLNKVEVCASSRPTSPDAIAMRRDFEVGIEAYDQRPRGVHEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2X1</accession>
    <name>A0A6A6P2X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_342353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2X1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="4"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="20345" checksum="C43DCBDEA4F03C10" modified="2020-06-17" version="1">MPTALLLIADGSEEIEFVTPYDVLTRAGFSVKSAGVNLENRTHAVCSRNVRILPDEPAVQTMVGATDFDVLILPGGGPGAKTFCDTPEVLDLIRTYRAAGKVVAFICAATTALVKSGGDKVKVTSHPSVKAEIEAQGWQYADEEERVVVDREVITSRGPGTAILFSLTIVEALVGKGKREEIAGPMICASTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P344</accession>
    <name>A0A6A6P344_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P344"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="668" mass="74975" checksum="9503DA8D11D321DC" modified="2020-06-17" version="1">MNELQPGDYVLIKGAGDRFMRPAVIYPADRPEIPSNFRDEKPAGNYKCVLVVGKMVFVWVHVDSLHEYSDEYLCSHRAQFEEHGAKDIWEAHQFVMEHAFPEIEYWGEFLRQTRRPQEGVTSNTAVASRGMGSIYSGPASPFQSQVTRWETFSREFVSSTTTYESQQQPMLGNVGDLNPQQPEGPPLEDDKKGKSPIQGQTERRPTEDNKTGKKRVRAPRKPAGTATQKKTAGSTTSKRNAGRAAQNKKDTATRKKRVEFASPPPSPCPSDDTEYGGIPGLPYVKTEDTDEPPSGVIASLDKDELEIIGERPKERPVGSFTTGLEKMPTQAKPVTSAMKHKNLIASSTKPEDTPAVEDIKGKKRLNTEVENPNQVEVPNRDKRSKKSSEMPEMIEVPDDNKNKQTGNFAETPSEAKTTSKAREGVRFDVPSNGGQPLRIIKPDNKDIIKIPNAGPNVVTVIVGKDTPEFFILPLESLKAHGHIVKEFEYTADSGILFDVRKSWSIPGLHFEPIAQFLREGEFTPKIVKNSSGDDELESVTKHDLRGQELLPFLSRVYLVAAQLQLMDIILLAFQKIVMFDDWPLKDALLLARCLWSRKTPGFEDECEPVMKEYVLDFLAERFDMYNLVMPEVFWEQLSHDKDLKIAVLEASLQKMKEKLTNGASDNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P367</accession>
    <name>A0A6A6P367_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_420962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P367"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="18209" checksum="3CD1F9BC8E01D90D" modified="2020-06-17" version="1">MASPWGGTDPYEMCREHKIPWFGEPAPTGSMRIKSKMPHMAAPGHGYFSEDTILDAYTAGLRPSSMLNPPLRTRDYHAVRTQWGRNERTHVDFDERRRANLPAPGSGSPSHWAQQHPRPRPMGCGPAGPTLLFALPEGSERKAQVKGEGAGGLPSARRGESTINVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3E2</accession>
    <name>A0A6A6P3E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_219175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3E2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="16623" checksum="8D2ACFE9BA2EEE7D" modified="2020-06-17" version="1">MVERCAPRWGGSSSGATAKPLEAGRSCGPRAVGRAALRASNDRRAAELSSTVQPRADSNGQGGVAQEPGAQQSKMGPASTLLPPVAPNARSAIRRWPVPNTLLQASNGVWAAQAPLRGCSAPTLIRPYHSGLSPVARWGKASRFLPGSGSLFSALKAARAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3M3</accession>
    <name>A0A6A6P3M3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_385405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3M3"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025583978" evidence="3">
        <location>
            <begin position="22"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="119"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="566" mass="61836" checksum="641563B1340FE530" modified="2020-06-17" version="1">MGLYAVLFVSLLSLLLGFVHNTTSTSSCRCFPGDLCWPTPEDWDAFNSTLGGKLVATIPIASVCHYDNFEAYDEEACAALRDIWFFPETHIVWPSSIMAPFFTNNSCNPFLPANVSCTLGNYVSYSVNASDAEDYQKTMHFTRRHNIRLVVKNTGHDYNGKSTGAGAVSIWTHNMKDIEMQTYSSSYYNGKAVKMGAGVEVHELYEFADAHDVIAVGGNCPSVGVVGGYTQGGGHGPLASKFGLGSDQVLEWEVVTAAGNILTASPNEHADLYWALCGGGGGTYAAVVSLTAKVHPALTVSAANMSFPNTGDNADQFWEVVGTFHASLPDMVDAGVSVIWLTTPDGFTLMPATAPDLTKAEIDDLMAPTLDKLEEYEIQYTYFSDEFPTYLDSYHAVNTPWNVSDHQLGGRFIPRTLIDDNNESFLATVRNMVDGGALFSGVAFNVTDAVPSPDTVAAHPLWRESIMHAVVGTGYSYTDEQINIEEQLTITNELLPQLEALTPGGGAYLNEGDWRQPNFKEVFYGSHYDSLNAIKARYDPEDRFYALTGVGSDRWAQREDGRLCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y0</accession>
    <name>A0A6A6P3Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_204390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Y0"/>
    <dbReference type="OrthoDB" id="406864at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051563">
        <property type="entry name" value="Glycosyl_Hydrolase_51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776:SF0">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025621993" description="non-reducing end alpha-L-arabinofuranosidase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="495"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="684" mass="76343" checksum="30725D353C27A5F0" modified="2020-06-17" version="1">MAVDLFAIFLVVTQSALAGSIAGRQGYDAAGVEVQISIDDTSGHNDTSPMAYGIMFEDINHSGDGGIYAEMVTNRAFQGSNWITGTVPGLDGALIVESENPSVPLGPVLTGWGPIGDVRMTLNTLHPLSDALPTVMQIDVPAYATGEVGFQNFGWWGMDVRPQTYTASFYALANEPRYMDNSTTFTVSLRSNLTGEVWASTTLDTLRLPTLDYVQLNATIENGVTAPNSNNTFAITMDASEVAGQTFYFDLMSLFPETFRDRKNGLRKDLAEAYVDMGVKFLRFPGGNNLEGVSVDARWKWWETIGPLKDRPGRLGDWGYFNTDGLGLLEYLEWCEDMSIEPVIGVYAGFSLDIYGQVGTDWPEDRMDEVLDEALGLLEYCMGDTSTKWGAMRAEHGHPEPFDVNFVEVGNEDWFSATYPYRWNAMYNGLKAAYPDITIISSAFDENDDYTISLPDGTIWDTHHYEEPQYFISRFDFYDNWQAETGNEGVGVFLGEFSVYQVDTPSGVVDYSNPPNLHIFHPRMISALAEAVYALGGERNPNTVRMSAYAPTLQNFNWYNWTPDMIGFTADVTETVLSTSYWWQWMFSRFTGSKSVPIVPTSGDFGPLYWSSQWHEAANKVYVKVCIKGIALQPNADCHSSSTSTIPRPFLSRSTSTCRTWPSMPRFSQPTIRMRQIPSSTPTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4M7</accession>
    <name>A0A6A6P4M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_370916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4M7"/>
    <dbReference type="OrthoDB" id="3650630at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="28020" checksum="B951531D20BBE3A6" modified="2020-06-17" version="1">MSISSGAERRYSIRNRPTVPTAERARNQEALWAVNFALGIEDPVLFDDEDADQGVQGEPANWRTWFHPFESPQEMWLGLGIVAAGVAGGDGGLGEDVWGAWRGLVEAGEEGGEHKENIGPAEGDAVGNASAIRPFAHGAYVSPYATPLNDRPEGPLGASNRYASPSASFSENVEKGQKDSDKARVNLSFRTKTQFYSLLDRIERSSFAGAMFLEAYAEHVRRDLCRECWFKAFVSDVGEDSEDDWGENEAVRTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5F9</accession>
    <name>A0A6A6P5F9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Soluble quino protein glucose/sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_281865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5F9"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025591598" evidence="1">
        <location>
            <begin position="22"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="2">
        <location>
            <begin position="34"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="426" mass="46038" checksum="67CD047375E066DA" modified="2020-06-17" version="1">MLFNSVAFTALVGGFLPQVIAQSCPTINPTAGQPQMSSGYQTRVFTNGLSSPRTIVFDTEGNMLVVEQGGGGVRRITLRDNGGLDVCPDQSTTIIPDASLNHGLDLSQDGRTLFVSSMSEVYAYSYDPSTGQVGSSTTIVTGMTQGGHQTRTLLASKFVNGTLLVSRGSDDNLDDQAVDENSGHSFIKSFSVDPLPSSPYDYASDGETIGWGLRNSVGMGENPYDGGFWSVDNGVDNMMRNGQDIHTNNPAEELNYHGIITDESDPQRGLNFGYPDCYAAWDVNTIPNNQGMEVGAQFLIDNPFVSSMSDNICQTQREGPRLSFAAHTAPLDVTFRADGSAAYISFHGSWNREPADGFRVGRVDFEDGQPVPSANTQDNIEYIMQNSNLQMCPYSCFRPVGLTFDNDGRLWMASDSSGEIYVITGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P616</accession>
    <name>A0A6A6P616_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-phosphatidylinositol 4-phosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphosphoinositide kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PIP5K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_384648</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14425"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.68"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="2"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P616"/>
    <dbReference type="OrthoDB" id="20783at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000009">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase its3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="13">
        <location>
            <begin position="326"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="67"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="776"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="783"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="893"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="922"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00078403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00080374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00082306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2459445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="977" mass="107990" checksum="493FE9B81BA1BFF7" modified="2020-06-17" version="1">MRSQRALARLGLGGSAPTAERPPSNLSSVHQAPAPVLSPAASLITNCPNSSPANILGLALSGRALPRSSAAPSPVGLHGPSLTGSASPSCPQQRRRRAAPAPCQDSERRLPEDLPGKTNKPLNTPTVDEAGSFANRPTTNSSGSTQTRLEPATVNGDGNVSSKSMPVPPKSDPPTSKNSSTLADGSLRPPTSSHRVSSPPVFAQGVQPSPSQMPGKLQQRHTLEVPKVATPSRISREYQPGINTSEEVISASGRFSPNTPTRRRGSLSLVRRATRSIHSEMHLDEVQQDEDIARWAEHIKQKRASKRKRDEEDDERVVVGTKVDQDHANWVTAYNMLTGIRFTVSRTNAKIDRELTDADFVARHKFSFDITGNELTPSAKYDFKFKDYAPWVFRHLRAIFKLDPADYLMSLTSKYILSELGSPGKSGSFFYFSRDYKYIIKTIHHAEHKFLRKILRDYYNHVRDNPNTLLSQFYGLHRVKIPYGRKIHFVVMNNLFPPHRDIHRTFDLKGSTIGRDFKEDELDKNPRATLKDLNWLRRSLHLEFGPTKKSAFIHQMERDVKLLQKLKIMDYSLLVGIHDLERGNEENLRDKTLQVFQPGGEQAEETPHNMLMRTPSKLENARKAKELRQLMWSQKPIPMDKSINKMPDDVQEGKKDFYFYSDDGGFRATHEDDSPGEEIYYLGIIDCLTYYSLIKRGEHFFKGLTNTESQISAIPPERYGDRFVKFISGITKTRERAEAEKLAESTNAHPLTNAPVPDPGVLNDPRLAGVNITPAALTNEPRSPSEHVVHEAERVAEKTRRKGANEDEVPERQIKTVRNQSTERGEVGHTLPVVEEAAESGSTGGKSGEASPNPAAVGKEFGPSGSNTVSEKPPPTPPKDRVASGTISAASFPTPPNHRPLTPPKDGAGQPEAYRGAGGANEDEKSKGPPTPPKDEGNGGDPEKERGRGREKELPLLPVPKFTEGITASPSPAPARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6M7</accession>
    <name>A0A6A6P6M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_338838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6M7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="98" mass="11417" checksum="092C4710960A0EEE" modified="2020-06-17" version="1">MTCRWTCRSRTATWRWAAWTMTRLWVWVPVLVPVLPVLVLEGRRRGRPAARPNRVRRSGAARSRTTIRTTTSSTTRSWRGNSRRSWLRTASSCTADRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6N3</accession>
    <name>A0A6A6P6N3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_370337</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6N3"/>
    <dbReference type="OrthoDB" id="2420415at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="577"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="716"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="797"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1205"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1027"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1086"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="811"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="846"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1260" mass="141761" checksum="F60F12EFD098A1EF" modified="2020-06-17" version="1">MSHPGKTAPRLIEDLYNYNPRYDSVIGRNILTDPPPLFEERDVHLQTLPKHACRHTFLLKDNQSELPRDDDPQWTLKVAAICKTCRVHVDLILNSQAKGQADPEGYLQIRVKPPQLKADYIRLLQDPACLRKRLEDAIRENPERQDLQRSEPVEVLEFLSTYLRDVLAPNRTRNRIPAKNRRFLVSFGNDLDDLFRDLGFKDVYEGSDRDKQWIMPDVPEHDALAVDTPRTFIEDVREEVLTIIDRKPGEQKAKLTRGLKVSSPAISHIHRLLGCHDYEKTPAARRAADQSAEEHPYYASLGAVGDFADDLVYFAYRRQAECDAVNSPYYFECLEGIAEGRKSENLQTKTAILASEGKISRKDVDRAYAYFGIEKAHVGVLSDEHIIGQFQSRLQDAAPAQEGTLREMLRVIGQARQSETIKQAASNTIETYEQALNWLNAEKSTDDNFLISLYQLKTNDAQSNQEIGHKAIEIIARHRRSEKLYTWLASGELTEGEPEMDVGRAFAILQFPDRTAIPDEQLLNALLLTRIEEAPTRREEFEQAYQILCRTRANGDPGIAGEVSFSIDSRPPEKWPVGFHNIGNTCYLNSLLQFYFTVKPLRDLVINHDKAIMDMSPENLRRKQVGSRKITAKEVTRAQEFVRELGNLFEGMITSPDLVVKPEVRLACLTLLASSKDMASRRKSTITGDRPSLGEIDGMPVMGPVMRPASFQKIEETAEEATSPASHTAEAGDSHSDVTLVGGDERRRKSVDVSMEDAVKVSKPQDGVDVKNADTPTMVESPNELSADHLNRIASPDRSVPLVDGAGKAQSVGNGPDQQQPNGSDSWITKTENEASSSIADKPEPPSRPPPVPPRPKPAEKENDIEDAVFAARQQDVTEVIDNVLFQLECAIQADDIDEDGEQIDIVVWTHLKAKSVETKQELFNNLIVDVAEGPRDIYDALDALFDRHTVDLEDDVVPRYATIAHLPPFLQINVHRVGFDRERGVPYKVENHLTLEDVIYLDRYMRHGDTAKDEQLETKRQANWRYKDVMKQLKEVNAHLSRTETELDAAETLSASSELICSINGANGSGGDVHTDHDAQAKFSKAELLQNAEALKDEAVAIKRELEELSNVIGSPYEDMKGHPYRLHSLFMHRGTAKGGHYWIYIHDFTHNVWRKYNDSVVTEVTDMSEIFGQVASNPPTPYFIVYVRDDKKEELVDALCRHPAQPARPADVEMTDAEESADSTNKEQMQVIDGVEYGNVSGVGWNPSGADQPPEQWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6P7</accession>
    <name>A0A6A6P6P7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane-associated, eicosanoid/glutathione metabolism protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_281994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6P7"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35814">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35814:SF1">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="15985" checksum="69C8B733F686FB61" modified="2020-06-17" version="1">MKTNAVQLPVAGTWALPFAAYYAFLANRIVYYRLKHSKYSGESTGEAGTESSDPAADPLFCASRAHANFGENVPVTLLLAIIAELNGADRRRLHYVLGLLLALRVLQAELGLARPGGRAQGRTLGYFGTQGIMLGLAGWAGKLVGYSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6R5</accession>
    <name>A0A6A6P6R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prefoldin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_362226</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6R5"/>
    <dbReference type="OrthoDB" id="248120at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23161">
        <property type="entry name" value="Prefoldin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000003">
        <property type="entry name" value="Prefoldin subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="12697" checksum="DBF146432D68105E" modified="2020-06-17" version="1">MADPKKQFEDLSDDFRKLQNEGRQKLESQQQENKSVQKEFSLLSDDANIYKMIGPVLMKQEKSEAVMAVDGRLEFIEKEMSKRIEKQIGEMQEKSEKKKMEQQPAQVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7C7</accession>
    <name>A0A6A6P7C7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_180671</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7C7"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000684">
        <property type="entry name" value="Putative glycine-rich RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16925" checksum="D16324E2191262DE" modified="2020-06-17" version="1">MSKLFIGGLAWHTDDATLRAKFEEFGHVEEAVVVKDRDTGRSRGFGFVRFSQESEADAAIASMNNVEFDGRLIRVDKASDKSGGGGGFQGRGGYNRPQPGGPPGPGMAPGGYQPYGGWLSSTGVRRWWRPDAVGSGPAWRVRWRGVWRATAPRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7E0</accession>
    <name>A0A6A6P7E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">F-actin-capping protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_281388</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the F-actin capping complex, composed of a heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the F-actin-capping protein beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7E0"/>
    <dbReference type="OrthoDB" id="9979678at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.570:FF:000001">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000005">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001698">
        <property type="entry name" value="CAPZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043175">
        <property type="entry name" value="CAPZB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019771">
        <property type="entry name" value="F-actin_capping_bsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01115">
        <property type="entry name" value="F_actin_cap_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00192">
        <property type="entry name" value="FACTINCAPB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00231">
        <property type="entry name" value="F_ACTIN_CAPPING_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 10" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="277" mass="30808" checksum="921327341628FCC2" modified="2020-06-17" version="1">MTASVDPFDSALDLLRRLNPRDTAANIERLCALAPTLQEDLLESVDVPLATRRCRQTGRDFLCCDYNRDGDSWRSPWSNEFEPPVEDGEGVVPSERVRRMEVRANEAFDVYRELYFEGGVSSVYFWDVDDGFAGCVLLKKSVPTATAAGGMKSSGSWDSIHVFEAADRARTAHYKLTSTVILNLGGQADALGNMDLSGNMVRQVEQDMPITDDDASHVVNVGKMVEDMELKMRNLLQEVYFGKAKDVVGDLRSIAPLSETSRDRATHREMIESMGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Y8</accession>
    <name>A0A6A6P7Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_179846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057214">
        <property type="entry name" value="DUF7892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25422">
        <property type="entry name" value="DUF7892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7892" evidence="3">
        <location>
            <begin position="813"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1267"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1178"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1267"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1318"/>
            <end position="1328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1328" mass="148716" checksum="AEE5D31D74579648" modified="2020-06-17" version="1">MENGVSEIEGDSLHHVGSKRKHGGEGGHAEKKRRVDGAGAVQLPPQVWQHIFRHLPPSALGRLLRVNKLFHKCLTSQTPGPIPGGSRTGRLRIVAADSIWAASRREFDRDLPKPLAEHSELDMWKLIGGKRCQFCKRLPGQNFSPESPWDGGPGPDGVRTVWQFAACMCGSCLVEQSFNESGLLLSSASALISALPCTFLTQNQHVVAASTLQDLQTIPANITVTKHYFKPHVEDIQEQFEDARALGPAAAEEWFKGLEGIGKQRIADAARWERWELRGGRRALSLNASRETSTRASGVGLPQRTASQSQPIAQPKHDRASPASITQPPPKPPAQASPPLEKAQPMAPNQPSTAGRANRNQREVELHKAARKSEIVQRCLTLQPPISQNVLEHMGSFKAAIMIPRPLTDNDWELLKPRLLAQREEAERKASEQVTSAPAEPNPNEDADTRAEREQRQKAESDEAQEALRLKLEAYADEMINRDWNDNTITRDSCPQFAASVLTHVRARFYSDIATEDEERSKAGLPTLEDVPNLPPTRKLLLDHMKYVYTSKIKPKAEAKRKELFLCSQCEGSKYYGFEGVIQHYGAKHTSSFSVGNVIVSWQTAEWPLDPPFHPEPSTVVSTGLNSMQPQGNNAQGYQQGRFGRPSTAGPRMPRNGPRRNTQISPSPYGHHSYTPHAQGPFPPPQHPPPQHAPPPAPAPQGYGQGYPPVPAGYPPAPYGNQYPVPPPPNPYHSYHQGPPPHYGPGNGYYTSGYPPQGMQPQTGYPNGRPMSHYDMARDTPYGYQDRISGAAAYPPQPDPLPQAPSFPPDHWREVADVGARLWTAVTSVDAPQSVRVHVSIFHVALSFKSRFGVEPTPDLFLDVLDKHELMRPMGNVQGLVCKLCSLGTRGKASCTSPTSPRAGENAISYSVLSLLSHFKSIHIERARYAADRVAPSWVEDMVLLPSPDILSEFLHNLRADPETTEYFAMAIRHELSNQRDRVDVEPPLRSVTPGQHRFVEDQRAPLSRGSRTPLMATRSEHGTNGSASPQHHDADVADRADRFLSRLNPEGEDGRRDDRDSQPPHGRTPYDAPGEPQIHAPHSGPSRGPSIEPYPGEPAMHYYESVPRQPYDVYDNRREHPSHVAYDSPERMARSRSRHSARHARYEEIRNRIRGHEEPFRRRSDRSLSPRPRNGHHSPEIVYYRDSRPDHPVGSEKVYRPGYDSHIRVRPMDPYYLDRSGRPALVYVPDPYRPMPSYQPPAGAPDPEYEYLHGPTGVYDDHHRTVLVQERRPYEPRVVRGSDIERERRYYEPEHRRGYEEEDPMQARGESRYVEQQPPPPPPPPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P828</accession>
    <name>A0A6A6P828_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_299422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P828"/>
    <dbReference type="OrthoDB" id="532630at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="9416" checksum="5C9DD1D29515145E" modified="2020-06-17" version="1">MHPHLHTKATKNCEDVIMALEECHARGFLYRAFGGCSHAKHEVNMCLRAERIERTRQNREQAKVRREKIKKVWDDIDANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P887</accession>
    <name>A0A6A6P887_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTPase-activating protein GYP5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_361215</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GYP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P887"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000044">
        <property type="entry name" value="GTPase-activating protein GYP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="12">
        <location>
            <begin position="320"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="193"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="375"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="427"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="695"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="758"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="846" mass="91459" checksum="B1218CFA3A9B99DF" modified="2020-06-17" version="1">MNGERHDGSVPAQNHPEHSSDAESRKPRKPSYSAERISTVGMDDVNLEEYKEATSNGASSRPSPPVLPPRVPPRDSSASSSTRQGFFATSAPPVEKQITAPPPPSRKLTSPFSWLSRNKTDNDKKPSISPPVAPTERRDTVSSMATLNSNPELMLSRMEDAESADSGTHGRATRNSLRDRFKFLRMREEAGIVSLDDDGGGGQPAPAGNASGVGSPAAAAAAAATTDDKKEAPDGSLPAPAMSRGPSSPGPAPTSPVPSMARPTVNPHLPPGTASGVAAGPGGDSAAPVDWDLWQSVVYEGPAAVARTSAEELGQAIAAGIPQAIRGVVWQVLAQSKNEELEGVYRELVARGSEHKEKGGGIGFFGAGKESGGHVNGTAAGKEKESIASSASSVHSDYSTPATINTNAPGTPPSKDGANGSSNGADIAKAQTALLAAKKQKAKEEAAALAKLEKQIKRDLGARTSYSKFVMASGLQDALFGVCKAYALFDESVGYAQGMNFIAMPLLFNMPEEEAFCLMVRLMNKYGLRELFVQDMPGLHLHLYQFERLLEDFEPALYCHLHRRGVAPQLYATQWFLTLFAYRFPLQLVLRVYDLILSEGLEGAILKFGLALMRKNAAALLAMRDMAQLTTFLKERLFDAYIDRAPSASSILDSGFFGAATSAADKEVYRADVLVQDACAARITPDMLRGYAAEWAELRRERREREQEAETLRAANAGLAAKVRGLEERAEKGDAEHVQVASELVRTKVENERLADANESLRGRVEELGRIVEAQTEEVERRMRGEMDQVMARNMQVHNENRALEEQLAEMEKVLVETKVQYAQINSEYETLKQKWNNITTMLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8N9</accession>
    <name>A0A6A6P8N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8N9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="21144" checksum="D31084BCD2DF50DE" modified="2020-06-17" version="1">MVCGNGDCFCALARGRARSPGPTLSCSRHCQGRVQHDTEALGRATCDVGNSLQLDRTGTSTDNTLQQRGCVRFSPSRAFGPSKHKTSRPTNTVPSTQLIKYPPRHLRGGARSRNPKTPHRTSPSPATLIASPSYIPAADPGCSESPFSPSNRPSSLDGWHTFAANSLSPSASASPSTPPAHLAAGMPIQRRTNPATTAFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8R4</accession>
    <name>A0A6A6P8R4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL30m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_334699</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8R4"/>
    <dbReference type="OrthoDB" id="509901at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000010">
        <property type="entry name" value="Large subunit ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_uL30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="8">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="86" mass="9959" checksum="9421030011744219" modified="2020-06-17" version="1">MAYFRITLIRSAIGLPEKTHGTLRALGLRKRMRTVFHPVSQDVAGQIMKVKELVDVQEVERALTKAEVKALRQPQRGFWLEYRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P902</accession>
    <name>A0A6A6P902_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Beta-glucan synthesis-associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_161043</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P902"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02180">
        <property type="entry name" value="GH16_fungal_KRE6_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="11">
        <location>
            <begin position="219"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="666" mass="73970" checksum="AA751B60C764C51E" modified="2020-06-17" version="1">MASQSSPRRNAPPHIRLNSGQDVIVYEDDSAAASSRPPPLPQTSSRSLIPGPASPSPLYAQPGSAAESAELLLPPQKSRTRRYRDESPDMRSPSPSPSRQEFSPSSRRTSWSSETSRESRVSPFASPFDDSRAPSRAGSDDEGVNTQTVSEKYNILPSAGLLLFPEDVEKDDYLHNPDPNDKEVRDCDLFSRRAMVNVGGLIFLTLGLLFMFIGYPVFAFFNNLVHPQPVGPCVSNPLCIELGRKVPLLENVRRGLVDPDTPDSVMTRKNHEGKTQKLVFSDEFNTAGRTFYDDDDPYWQAVDIWYGVTQDLEWYDPDAATTKDGVLTIRFDAFQNHGLNYRSAMLQSWNKLCFKGGHMEASISLPGRGDTIGFWPGFWAMGNLGRPGYAATTDGMWPYTYHDECDAGITKNQSQVDGLSSLPGMRLPACTCRNEDHPNPGKSRSAPEIDALEASVAFLDPPHGAGVGSASQSLQVAPFDIFWRPDYDFTEVYDKTISGVNGYAGGVFQQALSVVSNLNNDWYDDKAYQTYAFDYRPGDDGYVHWYIGDVDTWHIDGRALGHNGNVGPRPIPTEPMAMIVNFGMSNGFAELNLTGLAPLMPATMRVDYIRIYQDEGEEMMTCDPPEYPTTSYIAQHPEPYANPNMTLWEQTRYDWPKNSLVDGCDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P921</accession>
    <name>A0A6A6P921_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">RuvB-like helicase</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_413392</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P921"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 13 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="74"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2460366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="484" mass="51888" checksum="203CDE19CD9C005D" modified="2020-06-17" version="1">MPAAVQISEVGKTGGSSTGVGSRDKRTATHSHIRGLGLRSDGYAERDAAGFVGQVAAREACGIVVDLIRWKKMAGRAVLLAGGPGTGKTALAMAVAQELGSKVPFCPIVGSELYSAEVKKTEALMENFRRAIGLRVRETKEVYEGEVTELTPEEAENPLGAYGRTIAHLIITLKAAKGTKKLRLDPSIYEAIQKERVRLGDVIYIEANTGAVKRVGRSDAYATEFDLEADEYVPIPKGDVHKKKEVVQDVTLHDLDVANAKPQGGQDVLSMMGQLMRPKKTEITEKLRGEINKVVNRYIDQGVAELVPGVLFIDEVHMLDLECFTYLSRALESSISPIVILASNRGLVPITTSRSSPATTDASDLPPAAHGIPPDFLPRLLIIPTHAYTPDEIASIVRIRARAENLAFAPEGLDRVAQLGAEVSLRYALQLLTPASVVARMGKGVEAAKGTQITVGVKEVEEARELFLDAGRSVGVQSSGLLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9A8</accession>
    <name>A0A6A6P9A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinetochore component CENP-S-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_419317</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9A8"/>
    <dbReference type="OrthoDB" id="1872155at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="129" mass="14333" checksum="291ED3924E8AFA41" modified="2020-06-17" version="1">MADATEPSANEERLKSALWYYVSQKLDDELLRLNRNATPQFIGALTELVWTQTMSVARDLETFAKHAGRESINSADAMLLARRNESLEELLRKFLEEKRAAEGRVSARSGTTAGRGMLLSASNHTFSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA14</accession>
    <name>A0A6A6PA14_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_360815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA14"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF55">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="738"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="492"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="769" mass="82210" checksum="3EDA69F0D2215CE6" modified="2020-06-17" version="1">MGGRLVCAFGLSGAGALHGPGGGERGGEGPWQHQAVAAQYEHQHAQCGLAGGAAGARGRGRSSPWRAWRPGVANRTARVRAKPGPWRRTPPPPIPARRRVASSPTGGAAEVMERGRPRPAPGLRCHSPRPRSPTAGCPPSPYATLHFPHKAPGVQYVFVRASIAQPSDRSIASSSPSPPPCHCLCFPSAKMAVLETYDWIIALITIAFCGSAFGNGANDVANSYATSVAARTLTLPQVGVLAACTEFIGAVALGSRVTGTIKNNIIDLEHFEQQPSTLILTMGCAEFGSAFWLLTATSLGFPVSTTQTIVGALVGAGIASRADVSWEWKKGSVSQVAASWGIAPCIAAGFSAVLFGTIKYSVLNRADPFKWAMRLIPLYLAFTAGVLALFIVIEAPTADSLEDFGAGKATGIILGVFAAMLVVAYVFFLPYFYRRLVKEDTRVRVWHVPLGPLLWRENPPLYFPSHENYIVRDYYSSQSIAQAQGVGHVADNNGSESPDLIGKKDNGEVGVPADNGAAEKGPMGADQHRPGGASYKVEVIPPEPRERFLGPVKHLPLYHPKKIFGFIKYILLRGVTKDCVNFSNDNISKAHARAIVYDNKVEHLWTYAQVASAIMMSIAHGSNDVANAVGPWVAAYNTWLTGEINEDSDTPVWFLVVAGLLLGLGFWFFGYHIIRALGNRITRMSPTRGFSMELGAAITVLLASRLALPVSTTQCLTGATVGVALMNYDLGAVNWRQILKIFCGWVLTLPSAGLISGLLLGMALNTPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA59</accession>
    <name>A0A6A6PA59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_133135</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA59"/>
    <dbReference type="OrthoDB" id="296065at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="13">
        <location>
            <begin position="12"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="12">
        <location>
            <begin position="215"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="487" mass="54533" checksum="DB0237BB1063ADBA" modified="2020-06-17" version="1">MDKSSGDGGNVFLVRLVQVYESFRRAELEAIADLLEFKMDILDYNDDSPFCLVRLPSIQNARALISRTIIAHAIYVLWGSGSDYPSLRTSVREQSAHLWAPFAESSFRFEIDSFRGKRSMKEQRSIIESFSWLPLNGPIVMRGAELTLTVFEDWAAGDQKRRSQEQKPDSESQDPESAIASSSLPRPPQPKRLYLGQLIAESGRSHALAKYDLKKRVYVSTTSFAAEIALVTANMAHAAPGRLLYDPLAGTGSLPVACAHFGAMTCGSDIDGRMIRGKGGRRSVVGNFEQYGFKERWLDGWVSDLTNSPLRGLGDEEATRRAGWLDGIVCDPPYGVREGCKTLGKRREERNAVVEGPVYIDGKLSHLLDGYVPPKKPYSFDAMLDDILEFAAVMLVENGRLAMWVPTANENNIALVTPMHPHLELVSECIQSFNKWSRRLLTYRRLRAGEIDRSTKSRKRTYGTGVTANELNSFRKKYFEGFKPTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAL1</accession>
    <name>A0A6A6PAL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_333604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAL1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="17037" checksum="18780698E4E53A70" modified="2020-06-17" version="1">MAYPVSSVENGLQFDAISKYPCPSTPSLPTASLSISMAVKMLELFTSSPLTTVLLTITSFSIAPSSYTSTTDTQSPFLVRRTKLVCRNLDLPNLHYSLRRRGRLLGVVRKVRKAAVMREALRRASQEYRRGSEAGERSLTRWGSVVARGLHCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAR6</accession>
    <name>A0A6A6PAR6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein trafficking Pga2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_335618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAR6"/>
    <dbReference type="OrthoDB" id="4227028at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011431">
        <property type="entry name" value="Trafficking_Pga2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28199">
        <property type="entry name" value="PROCESSING OF GAS1 AND ALP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28199:SF1">
        <property type="entry name" value="PROCESSING OF GAS1 AND ALP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07543">
        <property type="entry name" value="PGA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="19408" checksum="C748F2444B98855D" modified="2020-06-17" version="1">MPDPAPSPAREGGVPDLSGTLSTWAANLQRNTFASFSRLRAVDYIRLVAIVGAYLLLRPYLMKLGAKLQRRDMERQNKESSENADAVAAAAEMNPNELRRGGRKAARAAEVEIPGVESEEDEEEGEAGPGMDWGRSARVRQRRFIREKLAEHEAKLREQAEAESDKEIEEFLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB08</accession>
    <name>A0A6A6PB08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_140270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB08"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19943" checksum="53565B5480951D7D" modified="2020-06-17" version="1">MWRAAGGRRAVGFRRAPKDAFVSRTEAGRPVGSLGSGARSLRPKTCCLFGVLRRLHRQWMLAEVGPFVRGPLGEGGLHDEALGGSREVVKRVKSVRGLEFGSRGDIQGGLERVCFEYPFHFVGFFQMRKKCGDQGPFVFRLFPPSKFVLTQESGSPCLERLTMAHVHMGGAFPWLFVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB45</accession>
    <name>A0A6A6PB45_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_297890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB45"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="49"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="547" mass="60425" checksum="4D92F686CDD305E4" modified="2020-06-17" version="1">MPTTAPSSAKQDSVEMVTTSSSMADEANRPGRILDLHKDFFFHRRTLYCCAVMSIGGFQFGFDLSAIAGMQAMPGFLQVFGFPDPTAVLGYGIDPTVQQLINSLMSIGAFVACVSVGPLGNYLSRKWSIVLGIVLNHLGVILMMVAKDLATLYAGRLIIGLANGYLDILPQLYIHETAPAYQRGALLGGFNAFIGVGLLVGSIAANYTAKIIGKEAYLIPLGLFLVVPSIIGVALPFLPETPRWLMEHGKEEKARKAIWRLRNQSTEPELIEAELEEIREALETEKRLSQGVKIFDLFRKANLRRTMLSLALLLSLSGSGALFLLGYGTYFFSVAGQTKAFEENVGMTAAGLVATIFSMWLITKVGRRTVLLFGFASQGICMIIVAATSEKGMTETIGKVMVAFTIMYIFFYNLCCAPYLYLVAGEIPSQRLRGYTLGIAIAISFFFSWLVSYTAPYFINPLELNWGPKYGYIWFGSNFIIFVCFYFWIPETKDRTLEEIDEMFEDNVPARKFKGYVCVRAHNAEIVGSQRVTGDKEGVPAQHLENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB58</accession>
    <name>A0A6A6PB58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_297962</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB58"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17973">
        <property type="entry name" value="DEXHc_DHX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001148">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000003">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044756">
        <property type="entry name" value="DHX15_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="115"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="305"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2461204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="771" mass="87416" checksum="E83B2CD00C8CB102" modified="2020-06-17" version="1">MADRRPELEESGRAKRQRTDDRDPRNNPYLAHHYDDAAASAAGPQFNSRKGKSNGAASGRSLDAFKRHETIAADARKAEDGPNNPFTAAPLSQQYFRILKTRRDLPVHAQRDEFLEMYHKTQILVFVGETGSGKTTQIPQFVLFDDLPHYYGKMVACTQPRRVAAMSVAQRVAAEMDVELGEEVGYSIRFEDKTSPRTMLKYMTDGMLLREAMHDWDMTRYSTIILDEAHERTLATDILMALLKDLSTRRPDLKVIIMSATLDAQKFQRYFHDAPLLAVPGRTHPVEIFYTPEPERDYVEAALRTVLQIHATEREGDILLFLTGEEEIEDACRKIRLEADELVREAGAGPLKVYPLYGTLPPQQQQKIFEPAPPPDVPDGPPGRKCVVSTNIAETSLTIDGIVYVVDPGFSKQKVYNPRVRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEDAFKKELIEQTYPEILRSNLSATVLELKKLGVDDLVHFDLMDPPAPETLMRALEELNYLACLDDEGELTPLGRLASEFPLDPALAVMLISSPEFYCSNEILSITALLSVPQIFVRPAAQRKRADEMKDLFAHSDGDHLTMLNVYHAFKGAEAQANPKQWCHDHFLSFRALQQADNVRTQLRRIMERSEIDLVSTDFNDKKYYENIRRALVAGFFMQVAKKDASGKLYTTVKENQSVLLHPSTVLATEAEWVVYNEYVLTSKNYIRTVTAVKPEWLLDIAETYYNLDEFKKGEIKTALLRTQDKMRRKAAQKASYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBR0</accession>
    <name>A0A6A6PBR0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein P1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">60S acidic ribosomal protein P1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_296397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the elongation step of protein synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBR0"/>
    <dbReference type="OrthoDB" id="2194681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="11226" checksum="789F7FBF3D084887" modified="2020-06-17" version="1">MSTAELASSYAALILADDGVEITADKLQSLIKAADVPDIEPIWTQLFAKALEGKDVKDLLMNVGAGGGAAAAPAAGGAAGGEAAPAEEAKEEKEEEKEESDEDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBX2</accession>
    <name>A0A6A6PBX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_273698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBX2"/>
    <dbReference type="OrthoDB" id="10266999at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF267">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="43"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="25059" checksum="4814D84A9A1CB64F" modified="2020-06-17" version="1" fragment="single">SRPLTVRIPTTTMQTSGPFCPRKPSLADILANTAPPPWTLTAFMAYLSQNHCLETLEFTMDASRYRKHYMKMVSRGGPTTPSADDVTYVRMLWQRLLDAYIAPNGPREVNLPSDVRDSILAQADAQMPPHPSTLDPAVHKVYELMEESVLVPFINSLHPQPDSAYNTSDENLHHHQQQQYHHHHHQYSSSADPASAYATPGTSVPPLSASPAHRASAPASSTSASPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC26</accession>
    <name>A0A6A6PC26_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S36, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_278147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase component 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC26"/>
    <dbReference type="OrthoDB" id="2116030at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020373">
        <property type="entry name" value="Kgd4/YMR-31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31601">
        <property type="entry name" value="28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31601:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE DEHYDROGENASE COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10937">
        <property type="entry name" value="Kgd4-YMR31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13535" checksum="8204E0C764F7C955" modified="2020-06-17" version="1">MRATLRLLSGQRQPMIRFVGKRHPTHHADPTPQTHPAAPAPLPNTFASYRQTAQQHGPLNKPFHSLGTAPAPGRIGAQPASALGDVRPARGEAWDRNELPARFRRRPLTPAEIEAVESGGASVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC53</accession>
    <name>A0A6A6PC53_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_266643</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC53"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="21332" checksum="17F9EB49B00C46F2" modified="2020-06-17" version="1" fragment="single">VGDGSHSVVEKVVNEETKSVYALKTFRRTVRKVCMVQRFTKEVDILRRMKHPHVVEFVGHYEENNALHILMKPLADTDLENYMRKPGAFPSCNSHLGDWFGCLASGLSYLHSRSIRHKDLKPSNILLKDARVFIADFGISSDFSFDSTSVSSSIASMTPMYCAPEIANKEEHGTKADIFSLGCVFVELTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC56</accession>
    <name>A0A6A6PC56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">MICOS complex subunit MIC12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Found in mitochondrial proteome protein 51</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_89447</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MICOS complex subunit Mic12 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC56"/>
    <dbReference type="OrthoDB" id="4037694at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031463">
        <property type="entry name" value="Mic12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17050">
        <property type="entry name" value="AIM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="122" mass="13675" checksum="83406D4ACA4D8AC1" modified="2020-06-17" version="1">MGFTTGFLGGFTLTTSLLYLTIALHRNNRVSQALALRQSSQTLNDIVEPPPALPPPPSARVARPSLVETAKDKWNAEVETLVRKVYDTDWNQVREQAEDNVGAVWRKIKDLGKETKEEGEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCJ1</accession>
    <name>A0A6A6PCJ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_88782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCJ1"/>
    <dbReference type="OrthoDB" id="2426396at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599:SF2">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025495427" description="GPI anchored protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="51566" checksum="E12BCE32E39CECA1" modified="2020-06-17" version="1">MARLQYLLSLPTSLLLLLAGNPATTSADRPWPYNLPAHAKYYPEDEIHVKRDIEVQERLARQTPIGVRKMSDDEGEKFYLDYWVFDMDGVDGTASSGPEYSEVAVHRRSRRSDIEAPLAYANASVQLLPPFNLHAEMQPQAEEFFRYFRRSYLEPRDFQCPAGTRACTDIDRPNSCCSTDEQCIIVEDTGLGDVGCCPQGASCGGGVSTCNEDDGYTSCPGTSNGGCCIPNYECEDIGCVYTNTATTIVQPPEPSTSAIPSYSSASTTTSSTSSAPTTTSTSSLPSTTSLPPSSTCSPGFRSCPASLGGGCCATDRSCGPVNCPPLSSTSSATANPPARPTSSAELVTTITSSSGPSVCPTGFYMCSAYYRGGCCRVERDCDSTSCPPGPSNTVVDSNGVTILATGSNGASIGFASVSSHCADGWNSCAQSDGGGCCPGGYACGPVCTATVSGQAVETVSRVPAISKAGRRRGGAELGRLVATFGIAVSVGMVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCR7</accession>
    <name>A0A6A6PCR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_89461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCR7"/>
    <dbReference type="OrthoDB" id="422106at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="557" mass="60142" checksum="83C0EED9F1E87A3E" modified="2020-06-17" version="1">MDIEAQQMPAVDPTMEMDIDMDIDLDLPQEQIDDFVPNNNVHPFDSVVATDGDQMASDPAPEKVHIRGLDTFATGNIKDYVAEHDCSDQFVKIEWVDDTSANLIYENADAARSVLDKLTAEGVGPTMVEQLRPAKRLSTHPDIELQVRQATLVDVKKPRAADASRFYLMNPDKDPREVRRRRLEAARKGGRSVDGGNDTGDYRRRRFDDREHRRRRNADHISGFSESMYDEDGDAATDTALGRRITRQGSTESSGSEYRRSRGGRRGRGRFAAEDDLFAAKMRRGDGRLRDRSASPLPDGGDGRLGFAEDDAGRRRRSASPSYAGGANRGKELFPSTKPSGAGVLSSSSTSNLNSAKELFPPAPAPKELFPSSLSSAKQLSPTNGRKRSRELFPHKTAISNHRRTAAFDAAVMDDTADASGIMGNKRPRSRGTPSLALEDRITGGPLPKAAASPHRAGGARSNLNRTRADSAGAADGASGFSIRGQADRGGEQLDEGFSIRGAAASTGGAGQGQAAGAKVKELFPLKTGGGNAGKELFSEKIKGRGGPRRKAEDMFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCX7</accession>
    <name>A0A6A6PCX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_382985</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell membrane</location>
            <topology evidence="16">Single-pass type I membrane protein</topology>
            <orientation evidence="16">Extracellular side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCX7"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13851">
        <property type="entry name" value="CuRO_1_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13899">
        <property type="entry name" value="CuRO_3_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000022">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000024">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000025">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0410">Iron transport</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025360033" evidence="18">
        <location>
            <begin position="25"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="21">
        <location>
            <begin position="33"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="19">
        <location>
            <begin position="158"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="20">
        <location>
            <begin position="365"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2461835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="601" mass="66223" checksum="148FEFD2504A4953" modified="2020-06-17" version="1">MAMSLSNFVAPIFLLLCFSLLSRAATVTYDFNVEWVTSNPDGQFERRTIGINGQWPIPAMVANVGDRVIVNVHNGLGDWTTGLHFHGLFQNGTNQMDGAMGVTQCAIPPGGDFTYNFTIQQPGTYWYHSHVKGQYPDGLRGPLIIHDPDSPIANMYDEEVVMTLSDWYHDEMRPLMADFMSVTNPTGAEPVPQAALMNETQNATFAVQPGRTYMFRIINMGAFAAQYVWFVGHTMRIVEVDGVYTEPAEANMIYLTAAQRYSVLVTMKNDTSANFPIVGSMDEDLFDAIPDGLNSNVTSWLVYDDSKPLPAAEFVDEFDPYDDYELVPIDAMPLLDQVDYSFNLDVKMDNLGDGANYAFFNEHTYVHPKVPSLYTALSTGSEANNPAIYGANSNAFVLQKGEVIEIVMNNEDPGKHPFHIHGHHMQLVHRSEDEAGLYEDMNVTQADFPATPMRRDTVLVRPNGNIVLRFRADNPGVWFFHCHIEWHVVSGLVATMVEAPTELQSTLDIPEDHWAACRAQGIPTAGNAAGNTEDLLDLSGAETSPDPLPAGFTARGIVALVFSIVAAFLGMAAISWYGAAPLGEVAMQQVQKRVAESGVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD62</accession>
    <name>A0A6A6PD62_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD62"/>
    <dbReference type="OrthoDB" id="3946172at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="780"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="830"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="907"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="994" mass="105207" checksum="BB482609D56192FA" modified="2020-06-17" version="1" fragment="single">SKPHHHHPVPQIRKVTPHSCTVALRICTTSLSHIHILEHYKNSSFPAAPFPTSISNLATRQNSAPPDLLRVEQAATMNHPPDRNASLPLAQFERQSEREQARLAYISAPQRAGRRKTIPVDAEYGLLQNADNNVRARWVQQGIWRAEWGPAWPKDSKNELVRIGKGVSPLPSGRWAHEDGPMEFEFGTTLFAPPSGGVRTNASRPDQQFEFQAGREYEWIADELAFAGEKKDHQAIRAEARQSAKDFWIECGIWNPAWASSPGFVWMHEEEPSNVVMSEAQLNDSSHITVSEDQSSSSPISPAQEGPRVPEFSIRRIFQFGVRKNGDEHAAEATPAVPPAQAVAAGDKVPHVHFASTGAPPAPTASTTAGSNGNSAPRPATITTSPPATAATRQATPPPAATPPRQATPPPPDTAGARSFFGSFFPSFSISRRRESRTVSPSRTEMSPGARGSQRFGRGSSLPPVETGAEIDITPAQRAARGAALTQSPDLPEFRPPAVPNTRDRPMRLSAAERLLQNIRAATAANAPAKSSPSETPESANQSAGGATMAREQMEEEQARVEEEPVLMEEEPAPMEEEPTEPKKSGRPAKSTAEQTEPKTAGTRRGRAATTKPAAAASAPEKKRGRAAKPTMEPERVQPKRRGRQPKDESAAPAPEAAPEPVCEPEPANKRRRKAPQQPAADATAPAPPTSTMILSRGRTVTLPESYRESRLQARATPAVAAAPPAKAASKPASKPASKPAAASPTEPAAAAPPKRRGRPPKAAAAAAPPKRRGRPPKPAAAVAAATKPAAVQAKKKPPTALGKRTRADAADDDEAEELELPAPKRRGGPPKAAQKAVPAPATPAAPAAPKKRGRPPKAAAMAEKAAEEKPAAKKRGRPPKGPTMVEVVVEAPPAKKRGRPAKEDGAAAAATAAVTAAAEDEAPLAPKKKPGRPPKRAAAEMDEPDEPDQPAPKRTRGRPAAAAEKKAPARKAAPAKGAGGRVTRSQAAKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDE9</accession>
    <name>A0A6A6PDE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_332146</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="4 14"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDE9"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000168">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Alg11), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="17">
        <location>
            <begin position="148"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="17">
        <location>
            <begin position="339"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="16">
        <location>
            <begin position="468"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="300"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="399"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00056799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2461443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="670" mass="74764" checksum="3D08B9BB4E40EAEA" modified="2020-06-17" version="1">MSLSWRFLLPDPTSTRDTQAWFLLLAVLYQSYRLSIPSYLLLPRYFIFLIVQSLFFLSCTWHFVRFAAGWYLRRKTTDRRRLLEKRVAIEQDDYDSSREKKQKGNNAQSLPPPQTDQKGEDDDDWKKVECHMTNSTTNGGPLDKDWKGIVGFFHPFCNAGGGGERVLWSAIRATQKRYPDAICCVYTGDHNVSKTEMIQRVHERFNIQLHAPTLVPLYLSTRHWVLASTWPRFTLLGQSLGSLVLAWDAFSLLVPDVFVDTMGYAFALALSKWLFPDVPTGAYVHYPTISTDMLDAIAAPPVPSPSSDPSPLTKSNTAAPSDHVKAQAQAQTKSEQQLNQSKGSVGGIHVGQGAGLRGKAKRIYWRAFAALYGAVGGTVDVVMTNSSWTRGHIEALWGPARARRRQTSSRRKALRTQTSGKDRENRGEAEGEDHEQVLSPRSVDVVFPPVAVTDLLRAVDVSAASEARRETVLLYIAQFRPEKNHSLILHAFAELLTQWPAFEARPRLVLVGSVRGDDDSMRVYNLRLLAHELHVRDDVEFVTDAAWPVVQGWLGRAKVGVNAMWNEHFGIGVVEYQAAGLISVVHDSGGPKKDIVVEVDGGPTGFHATDPPSFARGFGAALDLSPADALAMRLRARASSRRFTEEAFEMKWVAHMETLTALQEELRAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDS1</accession>
    <name>A0A6A6PDS1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDS1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="21765" checksum="D66F3E62DACCCF0A" modified="2020-06-17" version="1">MAGCKNPRGQRRGGAGHGWTAQERAACLLRVDEYRDGLVGRGSPRTREARFRYEVDSSGHLSTRFWRDADDAGGNSEAESLATSPGGMHSSTCLMGWARERAHTVEIFEAVPGWVEIRKYGFSSSVIVCLKLESPAQCRYNVALAMEEGDQRPENNPEATPVETRASGSDVTNFGLPYPLKLPFKWIGLKAKFESRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE17</accession>
    <name>A0A6A6PE17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spt20 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_375950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE17"/>
    <dbReference type="OrthoDB" id="1932706at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="2">
        <location>
            <begin position="59"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="679"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="766"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1087" mass="114398" checksum="723C0DBB37493333" modified="2020-06-17" version="1">MATTAVATRQRRESHRPSLSKASLRASTGDVAADRVASAKPVAEPIVRTPDYILQKHKGKPPSFIVHLHPAYFKLEGQDGNFPYNSPMRPLLDHIKTQTVPHEMLEELFQSRVNFYDGCLIVEVHDHKSAAKSAQPGAADAAEARKKSSLHAHNNFITPSPYAPLATSTKAENQTKAEAAARASSVGAPHSATEPNGTRDKENLVPQQGSSEKVASGPRIFTMVLFPTPRSLLEEVTMLANAPQPDVRTAKRQNSRDGTNMAQPPTPLSSVPPTPTTRGPPPNKRQKMVLDSNNIHEFEASVIRMTEPNLLLEPAASAKETEAMLKATAHPLHNEKPPPPKTRKRTVAELAADEAQAAEEERFLLACDDRLGPTAAAVGGAAEGQGAAVSYEPRFSRFKTLETIKAQHEEAERIKKEKEAREAHAKRMQTEAEAQKRIEEQKRAAQMQAAMLANQNRQQEMQQARMRAAAAAQTASANAQQGNMSHGGHPQQGSVMQNPQHTAQFHVSQGQQSSPVLRQHSPLASSPINNASAMNTHGMAAPPMMATSSSHGAGSPARPTSAVSHHQGPVGMVRNISQQQHGSQQGGASRNGTPQMMHGTPSMPQAVPARHTMTPQPRGGAQQRSPVTAMAQTPSMMGESGGTGMTNNSPLAHMLATIGMSHEQFKSLPLPQKHHLANQWRARQAQAAAAAAHQQQQQGGTGMHHAGSPQQANQTSQQVGTPQQQHQQQPNQGMPTTQEQMQRLVASQLQSRNLSPAEYNQQMRAQMQRMVQHQRQQAQQGGGPGQGSPTPVPGQSGMHRPPSQTGAHPNVGQVGPQGGQGMGNMGNNMDPATMARMQQFQQQQMVHQRNQQIIMRRLQHIHGGQLPPNIAEQIQAVGLMGYLQSLPPQHQMQLTQGLSNQGGGGQQGQGGGGQQQGQGGMGGMGMGAMGGGGGGGGGMGGMGGHPGGAGPGGMMGAAGQNFMGVSPQQQQQMHIQRMRQLQAYRAQQGGGGGQGGAGGQGQMGLGGMQGMNMGGMNMNMLNMAGNMMGNGMPQGMGRGMGQGGMGPGGMGPGGMGPGGMGPGGMGQGGMGQGGMGQGGMGQGGMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEI5</accession>
    <name>A0A6A6PEI5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3 11">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_276853</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3 11"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEI5"/>
    <dbReference type="OrthoDB" id="7939818at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000001">
        <property type="entry name" value="Glutamate-cysteine ligase Gcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000004">
        <property type="entry name" value="Glutamate-cysteine ligase Gcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="5 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="525"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2462230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="664" mass="75655" checksum="5A966826B72D7104" modified="2020-06-17" version="1" fragment="single">VLHSAVGTPLDWPEAKKVANHVRDWGIEQLLAIWRRAKGKERDALRWGDEVEYLVVCYDDAHHKVRLSLRQADILEALASDEKLLQEGGGVPGLQRGNANESDVAPVFHPEFGRFMLEATPGRPWGIGFKDLLDVEQNMKRRRTIAKEHMAPTEYPITLTTFPRLGNEDCTIPHYPVSGPKLRSQFVPDEIANPHIRFPTLAANIRWRRGRKVEVNVPVFKDENTPWPFHDPTVNYDLHKWPEDDDVRNGAAKANHIYMDAMAFGMGSCCLQITFQAKNIEEGRKMYDQLSPLGPILLALTAATPIYKGFLADTDVRWNQISRSVDDRTPEELGEMPLKNDRWRIPKSRYASNSTYISQDPRLRPEYLDPNLVVDVQLKKRLVDGGMDDLLATHFAHLFIRDPIVVFAEDLKELDLDKVDHFENLQSTNWQHMRFKPPPPGNDTGWRVEFRPMEIQITDFENAAFSVFIVLITRAILSFDLNFYVPITKVTENMETSHARDAIHTKKFHFRKNPFSQRSKISGCSESSTPTPTSRPATPLGPVEDEYELMTIDEIINGQHGGTDAFPGLIALVESYLNSMNVDVETRCELARYLDLIRKRANGSLCTAATWIRDFVRSHPEYKKDSAVSDRISYDLVKAAEVITQEEGRSELATAMLGRWGRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEY2</accession>
    <name>A0A6A6PEY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Glutamate synthase [NADH]</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">BDY21DRAFT_368389</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="24">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="24">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00045"/>
    <dbReference type="UniPathway" id="UPA00634">
        <property type="reaction ID" value="UER00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097054">
        <property type="term" value="P:L-glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000006">
        <property type="entry name" value="Glutamate synthase (NADPH/NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000022">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18 24" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16 24" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="26">
        <location>
            <begin position="61"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="970"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="1574"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="1586"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="23">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1192"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1198"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1203"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00057049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00068518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAF2462317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2145" mass="237231" checksum="BBA52572537C5040" modified="2020-06-17" version="1">MVQVSFAEQPETQIYDVIEPQEEETSGNVFPYQETPDNKSWAGTLPLKQGLYDPELEKDACGVGFAAQIKGKATHKIISDARSLLCNMTHRGAVGSDARDGDGAGVMTSIPHKFFLKNFEREQGIKLPPEGQYAAGNLFFKPDEDILKDTINIFEEVADQFDLRVLGWREVPRDSSLLGPAALSREPIILQPFVVVKSVYGEGKEPKPSFSEEFDYTYFEKQLYLLRKRATHVIGLHNWFYLCSLSNKNIVYKGQLAPSQVYEYYHDLVSVDYEGHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGVLKSNFFGDDLEMLYPIIEDGGSDSAAFDNVLELLVINGVLSLPEAIMLMVPEAWQGNRSMDPEKIAFYEWAACMMEPWDGPALFTFSDGRYCGATLDRNGLRPCRYYVTDDDRIVCASEVGTINIEPERIVQKGRLQPGRMLLVDTIAGRIVDDAELKQTVSNRHDFRVWIEKELLTLPNIYREVDQQGLNLEVKLSETSIQQDPRMKAFGYSLEQVTLLLAPMAADSKEALGSMGNDAPLACLATQPRLLYEYFRQLFAQVTNPPIDPIREAIVMSLEAYVGPQGNLLEMDQSQCHRLLLPSPILSLEEFNALTNIHTVHPDWTVKVIDLTFPKSEGVQGYMNALDRICDAASEAVEEGDNILVLSDRATSADRIPVSALLATGMVHHHLVRNRWRSRAALVVETGEAREVHHMCVLVGYGADAICPYLAIECIMKLHREGLIRKPLTTGQLIDNYKHSCDGGILKVMSKMGISTLQSYKGAQIFEALGIDDTVVDRCFAGTATRIRGMTFELLAQDAFALHEKGFPSRSIVEVPGLAETGEYHWRDGGEPHVNDPVAIANIQDAVRSKNDKSYEAYSKSEYEQIKNCTLRGMLDFNFDERNPIPIDQVEPWTDICRRFCTGAMSYGSISMESHSTLAVAMNRLGGKSNTGEGGEDPERSTILENGDTMRSAIKQVASGRFGVTSNYLADSDELQIKMAQGAKPGEGGELPGHKVSGPIAKTRHSTPGVGLISPPPHHDIYSIEDLKQLIYDLKCSNPRARVSVKLVSETGVGIVASGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRGRVVVQTDGQLRTGRDIAIACLLGAEEYGFATAPLIAMGCIMMRKCHLNTCPVGIATQDPELRKKFTGQPEHAINFFYYVANEMRAIMARLGFRTVNEMVGRSECLRVREDLRTAKTENIDLSLILTPAHTLRPGVATYNVRKQDHKLHVRLDNKLISESELALEKGLPTRVECDILNTDRAMGATLSYHISKRYGEAGLPQDTIHVNIRGSAGQSFGAYLASGVTLELEGDANDYVGKGLSGGRLIIYPPRSAVFQAEENILVGNVCLYGATSGTCYFRGVAAERFAVRNSGVTAVVEGVGDHGCEYMTGGRVLVLGSTGRNFAAGMSGGIAYVLDMYRDFEGKVNQEMVELSSVEDPTEIAFVRGLIEDHHHYTGSELAARILLDFNRALPRFVKVLPTDYKRVLEEEAAKAAEAKKKEYPLPILPGNPVRAQHEESKKHEREADDKEKKKNELLDIEESIGDAKAEKRRSTLVLDKTRGFMKYQRRSERYRNPKTRTRDWQELSSRLSEDELKYQTARCMDCGVPFCQSDTGCPISNIIPKWNELIFQNQWKDALNRLLMTNNFPEFTGRVCPAPCEGACVLGINEDPVGIKSVECAIIDRGFEMGWMVPSPPKYRSGKKIAIIGSGAAGLSAADQLNKAGHDVTVYERADRIGGLLMYGIPNMKLDKKVVQRRVDFMGAEGVKYVTNCAVGEGEITLDSLRADNDAVVLATGSTVGRDLPIPNRSLEGIHFAMEYLHKNTKSLLDSNLDDGSYISAKGKHVVVIGGGDTGNDCIGTAVRHGAKSVTNFELLPQPPPERARDNPWPQWPRIYRVDYGHSEVKTHMGKDPREFCVMSKEFVDDGNGHVKGINTIRVEWSKSATGGWDMKQVEGSEEYFDADLVLLSMGFLGPEDRVLGGEVEKDARKNVKTPPGHYATNLPGVFAAGDCRRGQSLIVWAINEGRMAAREVDSFLTGCGSQLPVTGGIVKRPPYELLNKVEGAPSELITAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKY8</accession>
    <name>A0A6A6NKY8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_173080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKY8"/>
    <dbReference type="OrthoDB" id="5375558at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF13">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN MOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="512" mass="56638" checksum="136851DFB27F4039" modified="2020-06-17" version="1">MAESNANKPPAQYPSPSHQYPSPSMQASYAYPPPQGGPEPYRASPQASSHPINLPPIRAMETAGAQPAHQGQPPMPTGLPGVPGHPYYPPPGSHALPPSAAAASGLRASKKEIKRRTKTGCLTCRKRRIKCDEQHPVCRNCQKSRRECLGYDPIFKPTGPQQIQPAPTSTQPQSFNPLPEHGYPPQVHGLPNVPPVVAGASGGGEYAYSPIDPALAGSEAGAVVPPPTSELPKVTPVAIDGLFGLEGQVEANPIKEEEIKDFNIDAARLIFAKEYAEGLDKMLETSWFSLHGLDVLVRNDALFRRFCALVNNFQVQPERHRSFGRQAQMAWSLLSLPRTASEQNGTNGEAKNVQTAELVARLEILECLLTARLPPASPMREVRYEQEANPNDPLYWQREFWRLMGDLVCLRETDAAVFMTIDTIIGRLRQILQQFENRDVLYSLVVCRYYGCRVKNFQEINVKNKYPQSDQDFISKIAIAKRFVEDEGKGDGSNHIIRAVCRMGMQSWSSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKZ4</accession>
    <name>A0A6A6NKZ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_175567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKZ4"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000003">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1500:FF:000004">
        <property type="entry name" value="Nucleosome assembly protein Nap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="44228" checksum="33BED2534FEAE365" modified="2020-06-17" version="1">MPPKFAEDLDRAAAAQIMSNPRLAANPALVSMLQGKLGSLVGRSSGYIESLPADVRRRVAGLKGVQKEHSKLEAEFQEEVLQLEKRYFAKFTPLYQKRAAIVNGATEPSEDEVKAGEKTEEEAAAAAAAAAAEEEGEEGTAGAKKDTEKAEEKPSEPVKGIPEFWLSAMKNQVSLAEMITDRDEEALKYLTDIRMEYLDRPGFRLIFEFADNEFFTNKTITKTYYYQEENGYGGDFIYDHAEGDKINWKPGKDLTVKIESKKQRNKNTKQTRVVKKTVPTESFFNFFNPPSPPAEDEDATSDIEERLELDYQLGEDIKEKLIPRAIDWFTGEALQYEQLDDFDDGEFEDEDDEDEDDLAGGGASSKDDDEEDESDSDEEGDGPKPNKEAAECKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL48</accession>
    <name>A0A6A6NL48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL48"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="24427" checksum="A231CF24B470ED67" modified="2020-06-17" version="1">MSMRDEEEWRRSMDGLRWCGSRALGEHWARELREYGWTRARIEEALTCMGLGNNDVARKERGAREWSNESGQNWVDDATVQEWLWGLQAPQEEGGMGSETEAQQRVEPRGGGERDYDAEQGCSNQGREEQDQGEQDQGEQAQGEQGQSEQGRKEHEGHQSSRQGVEKESEERDKKSESGKSSEVDEEEQMRSRESEELDPSDDIEAGVLDCWPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLR6</accession>
    <name>A0A6A6NLR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_260229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLR6"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20136" checksum="64392E7CEFCECF6C" modified="2020-06-17" version="1" fragment="single">QLQSPLLSLPAELRNAIYQHLLHSQTASSSRITSRTHPPYSSNPSPPSDVHTAILRTCRQIHHEATPILYSSANVFTAHPTLLSRLPHLLDPSRPVLMSSCADRISRWRVFVRLDTDARFGRAEARNAFDGCEELTVVAWQAQFGSSDYSALDAFLGVRGVRKARVKGTSDGFARWLEGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMS9</accession>
    <name>A0A6A6NMS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_417402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMS9"/>
    <dbReference type="OrthoDB" id="2019666at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26119" checksum="DBC41182147A42E7" modified="2020-06-17" version="1">MDEKVFKRFDGDRVTDDMLEEASKLFSENYPRIMGRVCLFIARFGISSYVRVSVNGRLAGNAFACRWAVDGMTICWVTQLVVHRDYRERGLASGLLNKIKLDGDDAYGLISSHPAACLAASKAFRSSINTVSLDFMKDHAESIMKASPEGYVRDAKLRGKLFDPKDDNGLVSSVDTEFDVDHEEPLEALAWVRESMEWPLGELFDGHEFILILQARRRSRPRSSSARRSGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNJ3</accession>
    <name>A0A6A6NNJ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_266825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNJ3"/>
    <dbReference type="OrthoDB" id="3933142at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="98" mass="11069" checksum="A3AF8567449A877C" modified="2020-06-17" version="1" fragment="single">MAPRWPQVNNGPENINEHATYLREACNQLQTVDRGRQNQVPWNIVQPYMESTIALIGKVLRQPAMEAILQHVQDAAKCTENIQRDITTIKNSVGLSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP31</accession>
    <name>A0A6A6NP31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldo-keto reductase ausK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_356048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP31"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19147">
        <property type="entry name" value="AKR_AKR9A3_9B1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000024">
        <property type="entry name" value="Aryl-alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF2">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="42586" checksum="1E367AA5C2EF5600" modified="2020-06-17" version="1">MSSAFSPAPEPKTELGRYRPLSSTAGIRVSPLQLGAMSIGKAWEASMGSMDKEQSFKLLDAYWEAGGNIIDTANGYQDEQSEMWIGEWMKERGIRDQIVVATKYTTHYRKYDLGPGRSVNYSGNHKRSLHMSVRDSLKKLQTDWIDILYLHWWDHTCSIEEIMDSLHLLVEQGKVLYLGVSDTPAWIVSAANYYARAHGKTPFSIYQGRWNVMIRDFEREILPMARHFGMALAPWDAIGGGKFQTKKALEERKKRGEGLRTLLGGSEQTDEEVKFSEALAKVAAEHGTKSVTAVALAYVMSKAPNVFPIVGGRKVEHLYGNIEALKIRLTDKQIEYLESLKPFDPGFPSTFIGPDPKVVGKVSGLLAGTAALSVVQSPKAIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP98</accession>
    <name>A0A6A6NP98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_356773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP98"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="17711" checksum="07B7970A56ADAC22" modified="2020-06-17" version="1">MLYELIGCVRPGALHEVKEVARTAGSIVLAHQGVIRGITNWGIFMLPKPTTKSTLKEDASLSLLSSPSSTASSSDASTATSSSPFARSSTSVLQPNTPKRAALGVPKHHTGHYFVMRFDASARSQHTLRKTMTKDPRVLRYSVVKMGTKLSEIKDVKGTADWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPV8</accession>
    <name>A0A6A6NPV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial 2-oxoglutarate/malate carrier protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_387906</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPV8"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000009">
        <property type="entry name" value="Mitochondrial 2-oxoglutarate/malate carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="42"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="143"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="241"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2453756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="333" mass="35715" checksum="AB74EDBB82F61FE6" modified="2020-06-17" version="1">MSSGSSTINSAKEKLSEAPSTMKSAAENPKQATTDFLHTPFMRAALPFINGGLAGMTATAVIQPIDMIKVRLQLAGEGVKTGPKPTPLSVTREVIASGKVLDLYTGLSAGLLRQAVYTTARLGFFDTFMKALTKNAESKQTKVGFFERAGAGLAAGGLAAFVGNPADLSLIRMQSDGLKPAAQRANYTSVIDALVRISKNEGIAALWAGCYPTVVRAMALNFGQLAFFSEAKSQLKDTSLSPRSQTLTASAIAGFFASFFSLPFDFVKTRLQKQTRAPDGSLPYKGMFNAFTKVAKEEGLLRFYRGFGTYYVRIAPHAMVTLIVADYLGWITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQA3</accession>
    <name>A0A6A6NQA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_292805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQA3"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF8">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="516" mass="54837" checksum="740C8386ED49D4E5" modified="2020-06-17" version="1">MFQAILASIPITAKLLDKRQGRSCSSVPAPTVEGATVVSISGQERNGSSTGDFPVFPRQSAGGSLANEVCEVNVILTHEGANDTVRIAIWLPLSGWNGKFQGTGGGGLIAGEFDSALAPAVQLGYAAGSTDAGLPSNSFDGTEWAGNEQLLKNFAHLSIHEMSVVGKQVAESFYSSPVEYSYWNGCSTGGRQGYMEAQRYPEDYDGILAIAPAINFNKMAVASAWPYAVMKEEGEFPQTCVWDAMVQAAIDQCDMDDGGDDDLISDPPTCDFNPFLIVGQNMSNCSITERHATIARKIIDGPVDASGDRLWYGLEPGTTFTGLATTTVFSISDGWIRNWVRPGYNTSNLNYDNFPGLFQQAVDKFDDLIGTSNPDLSGFAERGGKLLTWHGWADQLIFPQGTSDYRQRVQDTMGDGVDGFYRLFFAPGVQHCSGGNGPVPIDPLADLVAWVEQGQAPETLAAMSGSGSMAGNPSGNPSSGAGNGSQISRDLCLWPESLIFSGSGDVNAASTWTCAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQB3</accession>
    <name>A0A6A6NQB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_354672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQB3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19299" checksum="3131CD49E5D02C18" modified="2020-06-17" version="1">MRAEMAARSRTGRGRGEGPKSSHLGHGLLGSKGVDLVLARQTASCRGTLRCGTSIWRAGSLGYRGVSGLGRERFFFFFSNFRRVPLIASSSSFVVHVVSFAIGASPAAGPREARCRSTDTRRLASEWRRRTGAGASVRAQGARFGVAGCSALRGAVRGELLNFFFFLLFFFSPCGAWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQE7</accession>
    <name>A0A6A6NQE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multiple RNA-binding domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_356157</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM MRD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQE7"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12568">
        <property type="entry name" value="RRM3_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000247">
        <property type="entry name" value="Multiple RNA-binding domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000459">
        <property type="entry name" value="Multiple RNA-binding domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034482">
        <property type="entry name" value="Mrd1_RRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="33"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="344"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="527"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="646"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="751"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="196"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="267"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="878" mass="96864" checksum="2315E37FFBACB877" modified="2020-06-17" version="1">MSLETSKPTAPPATMPSSPPSSATTSPPLPPSSRIFIRNLPPSMTAADFRAHFSRNNAVPLTDARLFPRRRFGYVGFRNPREAVEAVKWFDKTFVRLSRIAVEVARPVGDEGLGMRRRFGYGKPKAHTIGNGEVNGNGTRGKRKRGHDEAGKPAENPKLKEFLDVMQPRRKGNLWADEGLTAVDDGKQEAEQYHFVRGETGNSDDEYQTVPKKAKKGAKGKPLEDSENDQAVDEPSATSDSAANQAGDGAPVSDADWLRSRMSNLPGLENEEAVEEEEEVSNDNAPRPCGSTDFESDQERLNKESEPDASPAQREPVQHEEHHLLENGENSEEDPNIEAIRRTGRLFLRNLPYSVTEDDIEAQFSTYESLEEVHLPLDFNSGKPKGFGYVLFSEPESAVAAYIDLDGSIFQGRLMQVLPAKAKNDSKIDEFVIAKLPLKKQRLLQRKAEASKSTFNWNSMYMNPDAVMSSVAERLGVSKSELLDPTSSDAAVRQAHAETHVIQETKAYFEGNGVDLKAFKNKARGDTAVLVKNFPYGTKPEELRKLFEEHGKVQRLLMPPAGTIAIAEFTQATQARAAFASLAYRKFKDSILFLEKAPKDLFSDTSKPSTVKRSMPLEVDQTAPKLSTTDLLAPTTAESPDAFDTSTLFIKNLAFATTTAGLTMTFNPLKGFLSARVKAKPNAKDPMHPLSMGFGFVEFASKADAQAALAAMDGFKLDGHALQLRASYRGVDAAEEARRQDDRKKAKARSTKVIVKNLPFEANKKDVRRLLGAYGTLRSVRVPKKFDRSTRGFAFAEFATAREAEVAVDALRDSHLLGRRLVLEFAVPEAGDAEEEIARMTERVGRQVDAVAVQKLTGQGRRKFVVGDRDGGEDRELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQG7</accession>
    <name>A0A6A6NQG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQG7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17068" checksum="8687F3E251D41C32" modified="2020-06-17" version="1">MVRTHPELSVSAFPRYPLPALLVSHRSPHAYPGGSGPGVVREDARWDGHRAVVRTSHAYTRRALRDSLRETADGGGVRNGAGDMGMPYADICSRSSPHGPTFTRLGMWGWVGCGVRGAGRGWGCGAAAPKQLGKQRSLLGTRRLAKHQPEFVRSNAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQJ3</accession>
    <name>A0A6A6NQJ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_292049</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQJ3"/>
    <dbReference type="OrthoDB" id="431497at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03272">
        <property type="entry name" value="ABC_SMC3_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000370">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000424">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041741">
        <property type="entry name" value="SMC3_ABC_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="11">
        <location>
            <begin position="522"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="838"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="193"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="673"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="981"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1208" mass="138591" checksum="9AB951239D890CCA" modified="2020-06-17" version="1">MYIKQIIIQGFKSYKDQTVIEPFSPKHNVIVGRNGSGKSNFFAAIRFVLSDAYTQMGREERQALLHEGSGSAVMSAYVEIIFDNSDERFPTGKPELVLRRTIGLKKDEYSLDRKNATKADVMNLLESAGFSRSNPYYIVPQGRVTTLTNMKDGERLNLLKEVAGTQVYEARRTESLKIMTDTDNKRNKIDDLLSYIHERLDELEEEKEELRAYQEKDRERRCLEYTIYHREQDEINRAIQAIDEQRQTGVFETDDNRERFGEGEQALADIDTEIAELKQQMEFLKVDKAQLEDERREATRERAKIELEVNALSEGQSAAKQAKARQDNERRRVEAQIREREAELATIMPEYTSLKEREAALKTQLSDAEGTRQRLYAKQGRSTQFKSQAERDAWLQREMGNINTFLATSKAVAMQNAEDIAELEQEIARLEKEVEDLRARINNRGDDMQSASEDVQKTKEERDQLQDQRKELWREESKLSTVISSAQQELDRAERFLSHTMDQNTSRGLAAVRRIKRQYNLQGVYGTLAELFEVPDRYKTAVEVTAGASLFHYVVDTDETATRVLEVLQKEKSGRVTFMPLNRLHPKPVSIPKASDAVHMVSKLQFDPRYEVAMEQVFGKTIICPNLQVAAQYARSHSVSAITPEGDRADRKGALTGGFHDPRQSRLDAIRQVSKWRNEYEVQRQRAQEIRRSIERKDQEITRMVGELQKLEQKRTQMDNSYGPLGTELRSISAALQARRDALESKRRSRENNDANVRELSEQYSEYEAELNSEFKKALNQQEEQLLERLGGQVQEMRKQYGELNTARSELEGRKTTIEVELRENLRLRLDQLNAHESELGASGGTGGSGSSNAARLKERQRELRRAEEAVANVESRLHETETSIDATMAQLAELEKSKVEQQNRQAEIARSIERHQKRMEKSMAKKSLLVDKAAECARNIRDLGVLPEEAFEKYTNMESDKAIKRLHKINDSLKKYSHVNKKAFEQYANFTKQRDTLQKRRAELDSSHKSIEELIEVLDQRKDEAIERTFRQVSREFANVFEKLVPAGKGRLIMQRKADRIQQDESDDEGMQDGNVENYTGVGISVSFNSKHDEQQRIQQLSGGQKSLCALALVFAIQRCDPAPFYLFDEIDANLDAQYRTAVANMLQTLSEGENGGPGGQFICTTFRPEMVHVAEKCYGVSYTNKTSSIDVVDREDALTFVEGMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQN2</accession>
    <name>A0A6A6NQN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_110715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQN2"/>
    <dbReference type="OrthoDB" id="3540210at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="579"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="766" mass="84356" checksum="7F33676141C9155B" modified="2020-06-17" version="1">MSQQAQGEVHTGYWVDWTYGSVNGATITLSAQGASYLVAFLALFVGVVGNHLWSIICYAAFQLRSTLKPKDSFHHELQGILRNSTLAVAVAVLKISEAGWRWRNRTKGWVGKSAVAVVSIVLYTVGFAAAGILSSKVVRGNSSAVLIKRNDMCGELFLPILSDRSKYEEQMVEPEFRQAFYQYQNEMYSLSSELDTYCNSPSLMTANCKSYATDLVHWTKEVRNSCPFNDNICMTNNSIFFDSGMIDSHTHLGINAPKEDRVAYQSALECAPIVTEGFSQYYDNVADLLPEEYETELNELPPQGAWVYRYSTATETNPTGQTLRYSNLSVTTFHEFTDSPQSRFNLMAVTGKPNPNATNEFFPTAELQRDGAITHLFFLSRGRQSLYPIEDPWFNATEELEIYPWEIEYGALDAITMYTSAEPIGVMGCAWSYKLCDLSGREGGDLCTPPLGTGLDDEAKKRVLEESGIHLNERQWQTLTRLRPATISFDLTGFAHFLGGRVLLASADEQDNGKLPDDQWMHEMEHLFGASMLGFQIRAFQFAAGFSDPIYAPYAVPAPPEVSWTCATQRAIRPEYHSFSVLGLSIVLGVGGLFILANGLLTVVTRSKHQWLQKKEFARLEWDMLDMIALQHTAYKLRGVDLEAAPVSVKPFLYPEGKKDLDASSRDEDAAAASGKNGPEPEVTESPTTPSTTAASDGFDYQAAKRESDASGKFEHRPGAEEAPASLANANSGPSPTTGVAGSPATPTDTATGEEPFNNEPATSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQQ9</accession>
    <name>A0A6A6NQQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_292407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQQ9"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053144">
        <property type="entry name" value="Acetyltransferase_Butenolide"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43233">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43233:SF1">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="69"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17659" checksum="37311252213FB478" modified="2020-06-17" version="1">MWVYTHDGQEYIVSNIAKDISHGFVQSAFGTSAMDWANPLAPEDFQTMLDNSCVFGLLRKTSDSSSSTTQIGIARLITDYVTLAYVTDVYIDPEYQGRGLACFMMSCCRDVIGAMPAVRGTMLCTSRDALIPFYERELGVRVHPQGENGFSILITPRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQZ7</accession>
    <name>A0A6A6NQZ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphatidylinositol-glycan biosynthesis class S protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_387642</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGS family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQZ7"/>
    <dbReference type="OrthoDB" id="28748at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019540">
        <property type="entry name" value="PtdIno-glycan_biosynth_class_S"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072:SF13">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10510">
        <property type="entry name" value="PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="584" mass="63324" checksum="2BE292561D14183F" modified="2020-06-17" version="1">MASTDGKATVERKPPPESQESIRTRRLVILAFWSVAILLGLPIWWKTTTIYRAQLPLQAMLDWADGKSCRPVFPLRIALDAPSLSSNDAHNLLRTTQHAIDDLNDFSAHHLRLRLRDHFDTRNASQEVHPDVGDLPAVGTPASFTDEDEGEIALSVRLLPGVSGTLPRAELQPYSPTLDVLYAPNQIPSPSSSAAAPAPLATFIANELQKLFAEEQDMLVYLLSSSPASSTSLQAQTTQPKPLSPEAAESLAKQSTRSFKYAPTYHLTFSLFTPTAAPSDWEIEEALATHVAPLLESLSTISNFTVDTQVQLYAAFSPSIREPEYDSNRGAWTLRKEDVSGFINAAEWPLSPSIGAGPTVNFVLYVPSPSQTPLVVADGDATATSWLVPQWGSILILNPTASNQQRQQQPTTLTQDDLAPAMLTFSSHLLSLLSVPSSPPSLPLRLRTLTRVRAASLLLSASSTLGSLARLALALPGIAIPDAVADAVDETVARLDAACADLREGRFGAALRSARVAEMRVEKAFFEPSMVGQVYFPDEHKVAVYLPLLGPVAVPLLMAVVKEIKKLREGRGKKEKEGGEKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR22</accession>
    <name>A0A6A6NR22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ANTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_423806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR22"/>
    <dbReference type="OrthoDB" id="44015at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16988">
        <property type="entry name" value="ANTH_N_YAP180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.150:FF:000004">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000025">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="410"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="723"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="546"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="680"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="729"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="751" mass="79931" checksum="05F2C5BF153CFE2F" modified="2020-06-17" version="1">MSGSFEKSVKGGTKIKLAAPKSKYVEHILIATHTGDAGVAEIFRALQNRLRDSTWTIVFKSLIIVHLMVREGAPDVTLKFLSHNPHRKLAINNFTEGRLMLQGHFIQTQGRNIRAYSEYLIQRASSYGSTKVDYVRGGEGRLKRLTVEKGLLRETESVQDQIRALLRCDFLSHEPENEITLTAFRLLTMDLLVLFHVMNEGTINVLGFFTPEHYFEMSHPDAERALSIYRTFVKQTDQVVQYLSIAHHYEDATRLEIPKIKHAPTSLASSLEEYLRVPDFEINRRQYLAQQEAKRLGKAKPADSKPAAKPAGVSSSGFPSPKASAAAPVKQEQPKGPAPDLIDFFESIEQNQQLMAQPTEMPQGFGQQPQPTGQFGQQQQPAFGGGMQQGMGPQMTGFPGQQTGVGGIIGQQTAFGGMSGQQQQSTNPFDQQQQQLQQLQQQPMQQPVQQPMQQPSFTSAPTGFVAGNGFFPGQQQAQQPQHQPFSSQTTSPLQSIPQNGVLSSFGQQPPQQQQPSPFGTSAPSSDLSGAQSTNPFRHSVMPPQFTGATATTPTASSSSPSPFTPSATGTTTASSSGLGRSATNPFAKQTTEFGSGSPSPSPFASAPPVPPMPSQPAAGSPFAPQPSLLLQSASTGTNPFARPASHSPASAGPTSSGGPFSPPGGTGAPAGAGGALMPNPTGSTNPFRQSAFVNQSSGQGWQNAQGMQGTMGGLEGLETVRVFPRPGEGSAGTGAGAGGLQGQQQQQGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRL6</accession>
    <name>A0A6A6NRL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_107260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRL6"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34871" checksum="E6E74DFCBCA89E0D" modified="2020-06-17" version="1">MALRGFATRSSSPPANLRPLRPRTERCVHKQKLSSCQRKGTALCCACYGKKRNRGGPQPSGVDAITLAGSECLVEDYCPHCRAYWKGRHGVQTRPNPPRPSATYQMESTATSVPPGSSGAEKIVECDLPSPWSSSWPKTAIESGKLTIGMIREQAAKKFGADDPSVIRLTHARRSGDKPFIPLLDDSMTARAAGLAPQSELLVGWKDSLVLEDIQPRKLFSEKFTMRVPGFHKGEAKLGLLRILVARHLNLPHERMVALYSPRGGLLEDDKALIDEDNLGYDGPRTPVTKRKVCWPRGRNTSTLEVGPKRTINTPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP7</accession>
    <name>A0A6A6NRP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRP7"/>
    <dbReference type="OrthoDB" id="3497519at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="183" mass="20898" checksum="7839F09345FFD69A" modified="2020-06-17" version="1">MLVLGGCPTLSLHRLEGLYFDADGNGTCATNPANVGDWMGNYVTVLLMPEPDRGDENDSEGNPTVPNPAERFPRPDEELAWAMPLEHVAKFWTDRFWNEDVERFPSDAFQVRPRVAWVQENRLPGKPFRYFVADKSTFGLTSPRPPDSGEWGYTRHGYLISRGNWNTVSRPPIEHENLRMRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS98</accession>
    <name>A0A6A6NS98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_373880</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS98"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="168"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2454609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="29463" checksum="9F8244AC4EAD435A" modified="2020-06-17" version="1">MDAQWTFPSSGVHNDHFSYVPYSAPLASRTLPQEPAILQSGYPEASQGLEYNVDLYSHQPHNTFYAPPPDCINDMPTWSYTTASSVPTSITSWPDTSTLPATHSHPTSPERGYFPYLFPQPGPKMLPTEVVTPEEARSNAPSESSVATSSNTRTSPSRSRHGQRDGPHECLECGEEFSHFYKLNRHTKRHTRPYVCQHAGCSRAFTLPKDLRRHLRTHATGVTRIPACYCPVPTCECSVKGFTRKDNLLRHMKRAHGVSGPEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSH8</accession>
    <name>A0A6A6NSH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_399902</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSH8"/>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="240"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="138"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="347" mass="36953" checksum="CA5A5EA19586512A" modified="2020-06-17" version="1">MSAEAQVAGLSPRAVAALAVVYTAIYVVPIYLSPTSRPAPNLSRDSPTVIRSRVRAASFSCLVCTLATLLVVTGRGGATLAEALRLMGWWPVHLADVARVVLLVAVLFAGPLFEAGVVEGGWTSWIRADGLADALGSWTGYRNYVAGPVTEELIWRSLLVPPALLALPHSALTTSTSTTTSPSTPSHATNNPTSTLTPTSLVLVLPLSFALAHIHHFYEFSLTHPRTPLFAQLLRSLFQVLYTSLFGAFATFAFLRCASLPAVVAAHAFCNWMGLPRLWGRVGAGSVVAVDGAGPDHAKGLRGWSEVRTDAGVAWSVAYYALLVGGAVGFYVLLWPLTESERALVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSN1</accession>
    <name>A0A6A6NSN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_326168</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSN1"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="70"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="111"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="27480" checksum="226A035E30A202AA" modified="2020-06-17" version="1">MSANVGLPTPRGSGTSGYVQRNLSQLKQREGRDGGGGGERGAPYPRAGTGEMARAREGHERGREPDAGILEHEARRRVELAVFELRDRLEDEGADEDEVEARAGALRARLEREREREARRAGKGRAGGGGAAARAAGEVKGLKMHQVHELAQAKREESERFRRALGIREDYVEGGHWRRQEERLREGLEERGKEGEGEGEGRERDGERGREKDRAGERERERESGRERIRERARRSPGSEEDESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSR1</accession>
    <name>A0A6A6NSR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSR1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="46144" checksum="4804E1E351AC9A99" modified="2020-06-17" version="1">MCRPLPHRWMVGLVRGPPIVKGEWFVWEKLGVFLYASPSPDNSRGWLSVVAALLAIPRYRRPSLAKPAEPVARLAAYMEIDGGSRRGPSLDLAAWERPVPSSGAGRLAGSGSPVTTTSVSPVYVVRRPEPSSSPARIRCLLQAMPDTTQVTTTAVAFCTRPHNHALFPSFAGTMPPSPEVPITAERAPLTVRLGRFDGRGGGLNGGKLAGHGEPAGRPDAQPVPFGGVAPLLACHAGLPTCPGCLLPGYHGGARRARVRAPFSTLHPASKATASDGALPRIASEEERRARLGYGQHLFDRRARGIATRRRTPGGLAPSSAAGGAVPGRRRAGEPSERRAAAGLRLREGARGLGLRSRDGDLPADETIGQIGEMRYVARDRTNSEAFKTTLQHAHAYARAADNGSGPRPRPPSSLQRGLIYLFVSSHPLGRSGLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTA0</accession>
    <name>A0A6A6NTA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_94558</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTA0"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="575"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="622"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="9">
        <location>
            <begin position="27"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="10">
        <location>
            <begin position="212"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="8">
        <location>
            <begin position="427"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="823" mass="94205" checksum="6EAFE92891FF10D2" modified="2020-06-17" version="1">MDDEYFSISKKPKTYKDLVLNNRDTGYQLVISALLGVSAFLAFCILRPRWTGLYAARKKQKHEATALPELSDSLFGWIPTLWRISDEQVLASAGLDAYVFLAFFKMAVKFLFVALFFSLVVFKPVHDHFPDLYPPNSTINDTMMSSTRVDGRFDVIHALQFPQDYYETDFLWMYLVFAYVFSGLMIYLLVSETGKIIKVRQQYLGSQTTVTDRTIRLSGIPEDLREESKIKQFIEDLDIGKVESVTLCRNWKELDQAVEQRMSALRRLEEAWTVYLGTRRVSRNPETLPIVQPSPPGPAFRLDAENNIHEDDRLLDEQDHVTPYPRERPTTRVWYGPLKLRYRKVDAIDYYEEKLRSLDDKVKALRKKEFKPTPIAFVTLDSVAASQMAIQAVLNPSPLELIANSSPRPADVVWPNTYMTRKERLLRSWTITVIIAFLTVFWALLLVPIAGALTEDTIKKVWPALANYIDDHKFVKSLVNTQLPTLAVSLLSVLVPYLYEWLSNKQGMISQGDVELSLVSKNFFFVFFNFFIIFTLLGSAVNFVSFWEKFRDYLTDATKVANFLARSLSGLLNFYVNYIILQGVGLFPFRLLEFGSVALYPVGLIGAKTPRDYAELVQPPNFSYGFFLPQNILIFIICMVYSVLRSSWRVLLSGLVYFMLGHFVHKYQLLYAMDHRQHSTGRGWLIICDRVVVGLLLFQLTMAGQLALQRAFVRSLMIAPLIIATLWFSLAFSRSYRPLMKFIALRSIHKAEDTDPGREIQEEAVAEADEQGVPAMPARVRRQTIDEAREFGARFVNPSLVMPLENVWIADVASHLTTNGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTQ6</accession>
    <name>A0A6A6NTQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_94926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTQ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="74" mass="8705" checksum="E8EF71C707CA9019" modified="2020-06-17" version="1">MRARWMGTSGEWVFLVLLFFFSFFLFCVRNGGAKGHGTKKAYRVANERRLLHWRAQHALYYSGTTLIHVITLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTR5</accession>
    <name>A0A6A6NTR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_308581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTR5"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000020">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16980" checksum="DD4366350EFDEB7A" modified="2020-06-17" version="1">MALPKRIVKETERLMAEPVPGINAVPHEDNLRYFDVKIHGPSQSPYEGGIFRLELFLPDDYPMVPPKIRFLTKIYHPNIDRLGRICLDVLKSNWSPALQIRTILLSIQALLGAPNPDDPLANDVAQRWKENQNAAIQTAREWTAEYAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTV7</accession>
    <name>A0A6A6NTV7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_291008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTV7"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="783" mass="87297" checksum="4596030B63C22C8D" modified="2020-06-17" version="1">MEDVPPSYECANTRDCWPLIAPYVCSLDLCSAALVSRRWHQIFAPQLWGNPASHFSPENDVLYVALTRFRRTLSWARPSVRELTHTLHLPPAHAEIYGGPHAEWLRDMLERLPRLQSLLVDELPFFDHACLTALRHASRARQREARSAPPGEVPVFPLRLLDAARCFNATSTGLAEALRHFPALMSLDLSGTSAARNESVLRGLRSLSGLRILKLRGLGLRDEDLRTLAAAIGTRVRSLDVRDNQLTDESAGVLLETCLAGRSDRLTPGQNQQPTASSPALDPRLGQDLLDIYESEDLDQRLRKKLIRDFVGRLAIEDGQQSGITHLYISKNLFTVAGVSRLLGSKRLHVLDVGTLPPVLGRVRRLLEPGHRETANFATPGAEQLIPVIASSDMSKFRYLRFNYAIVTEDAPLSSEFGPAPAEVEGDLGRSTKPRNVDTYELDATPMAAELEPESEPRYELPGDPVPPSAMPSRAKPSVARNMDEPVCPPVRRGSIYAPEVVDEEPVLNAAGPTRPGGNEMPSPTYTTSAHDRRARLTLEQSKEHCLHPGMIRKVRTLVLTDVPIKSSSARVPYRIVQFIKDCAEEVRIARLQANATYALPPGRSRQAAERDYARSIFAMRRIVLELAPEVDPDEMNTDAKRAGWKQTKSSTEDPDSEALWSAAENDFSFFNDDFECGLIDSEFSGRMPLTDDKFAIVEAQDAPQAHTNSTAGQHDAIDVVSEISKYRKRTRAAYERAQAQGTSTTESEEHWPGDVTVVWPQSDQRGTVDWYGNFYEKDWYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTW5</accession>
    <name>A0A6A6NTW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Velvet factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_399178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the velvet family. VelB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTW5"/>
    <dbReference type="OrthoDB" id="1746739at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="8">
        <location>
            <begin position="75"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="40002" checksum="8D2CAB066CD09261" modified="2020-06-17" version="1">MYGHREHFPPMPPSLTSPNSLPPHHNGSAPSSSTVPPPHHPSMMNQPSYQPSGPTHPGHAQPPPPQNLLAPLESSRNGKRYSLKVEQQPVRARMCGFGDKDRRPITPPPCIRLIIRDDVTGNEVDPSEVDITYFVLTVDLWSQDGSHEVNLVRHSTAAQTVSISTSTVTSFPPPPERPSYFLTPNPLPTMSYRPEYNGSAAMHAANMYAQPPAQPYGYAQATTAGPPPPPPQYAVPGPSQPPPAGMFTRNLIGSLSVNAFRLTDTENKVGFWFVLQDLSVRTEGNFRLKMNFVDVGSEHGQGLNTGKAPVLASCFSDCFQVYSAKKFPGVIESTPLSKAFAGQGIKIPIRKDGPKQLNNAHEYDNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTX3</accession>
    <name>A0A6A6NTX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_351529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTX3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="8102" checksum="027B63DF05AA1804" modified="2020-06-17" version="1" fragment="single">LHQVVQHWRCCNADFHVHVLHQDFVLLDGQAWLAYPHSNLRLTRVCHKQDPARYTVQHIVHDTMPHCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUB4</accession>
    <name>A0A6A6NUB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_373532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUB4"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025661800" evidence="1">
        <location>
            <begin position="30"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="111"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="457"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="631" mass="65465" checksum="0DF3288FDFE8D6EA" modified="2020-06-17" version="1">MRLQSSPPTFPRAAAALAVLALSAPPVHAQAQTVRHCPPPGPMYPLPVDLASDAAIQAANATFADLAAQAARDPSNTTFGVLGTPDTFWSVNVFSTRDASLGKFHYAPPGGGGDETTADVDDDSLWRIASVSKLVTVYTLLAKVGPAVWDQPITNYVPELAAAAGNETADEPSWRDVTLGSLANHLSGIARDYSLGDISTTPGLNASQFGLPDIPDSQIPSCGGITNGACDRETAMELLIERHKVQPVYKSPIYSNVAFQLLAYALEAMTGESIEDSFQSALAEPLGLNRTFFHTPTDDPNIVYPDTITTVLYWGLELGDASPAGGIYSSLGDLTTLGRSILNSTILPPRTTRQWLHPDAQTSDPYLAVGKPWEIYNVDLSSSTPNSSTTPSSTTTRTIHLFTKAGDLSVYSAQLLLDPAHGLGAVVLAAGSSASLTTRALASALASTFIAAGDAAAASEARARLAGRFVAPPGADARNSSLVLEVDAADAEPGPGGAPRQPGPGLAVASLVADGVDVLAAYGAALLAGQMPRVRAYPARPGEQGYRGGAGGGGGGGKMTFRLAFDVPTAAEEARTPRLFVDRCGYFGSGVDAAVYGGVAVDEMEVYLDGEGRAEGVEVLALGVRLVREED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUG1</accession>
    <name>A0A6A6NUG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_74293</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUG1"/>
    <dbReference type="OrthoDB" id="3862662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="438"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="619" mass="69228" checksum="AE986EA7BECAD380" modified="2020-06-17" version="1">MADEQAPRPSEEFITPTGTPSGHSSDNPSTAFAPRTCVRCKRRKRKCDKKLPKCSRCERLLIDCVYEPGHEGGSSMGGITQPMTIWPPLGEFDSDNMPTPPFNVLSMISLVSSTSQLKNSIVSQVFTLLRERNVNIRQSIETYFETIECWMSIVQRERFYAQLSRFQEHPESPTFAVLLLSMNLFIQDLDAVRTETGDFCTIYNQTKALVMLLQSSSSEPCIELVQSCLIISMFEFSHGESKRAYLTVEIAISMARCIDLHNHPTARKYDDIQDYYEAEERSHVWWSLFITERMICSAMLDPTLPRAMPTPSPDHLMPLGTTMWDPQANAWRTTFEQYPLSTSPNVRFRPFRRTAQGAVILGRVLDLANETARTGCPPPASAVIELDEEIQSHLMIHMEQNEDWERYCESIAALVSGLMILYVPYLCDNPNPIFNPHPLSPQSPFPIAPRPRSTLSSPPQTPPSHRAAAGVRSSATYSSSASSARSASSNSDIARAIDDDTKTLRARAYVACRVTANMSTDIAAAFDPRTGHDSWIRRIAPFAGVAAMQAVVTRIWLVVNEGAEVPDVGICGGGGSRDPHTDERTAIMLNVLRAFARRWGLPRKHVEEIDRVLNELAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUT9</accession>
    <name>A0A6A6NUT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rrp15p-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_306918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUT9"/>
    <dbReference type="OrthoDB" id="20949at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012459">
        <property type="entry name" value="Rrp15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245:SF14">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07890">
        <property type="entry name" value="Rrp15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="299" mass="32485" checksum="FDB4986BD98EEB5B" modified="2020-06-17" version="1" fragment="single">MPQSILKRRHADDNPRAKPAKRPKKFKKQREYHSSSEDEDEAPQNGSTDFKPVSLDDSDDDAGPAEDVDSGVRLDMSTSSKLKKAANEAAPEEGSSQSSASDDDDADSTAFTSASDSESFVSADSDASTSGTAAGKKPRSKRHDPSAFATSMNKILSSKLTSAKRADPVLARSRDAHKTSQTMAEEKLEARARHKLRDEKRAAKEKGRVKDVNGGEQGDEHGVSAAQVAEEERKLRKIAQRGVIKLFNAVRAAQMRGSEAAKDVRKEGMLGVEKREDAVREKSRQEFLAAMGKGEKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW09</accession>
    <name>A0A6A6NW09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PX-associated-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_349083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW09"/>
    <dbReference type="OrthoDB" id="2117459at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF2">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX-associated" evidence="3">
        <location>
            <begin position="12"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="230"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="428"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="813" mass="89110" checksum="DAC6595A8C77DA45" modified="2020-06-17" version="1">MASGSTSVPAAAELTPARLHALFDILTHAQTYAEIERFKHPETIDYYGHPFDVKPSSSRNDASSAPKSASTTAAPITTPPTTEPSAPILQSLLQKFALRLPGLRDVSPAFWQERLQTLMRELGAAELSESYDKGQLSLRRTLATAFSAIFEYAARGAFGGFDRRDFNLAVAMKGMAVEDERMDNQRKEDEKGNAGEGEEKDQKYDMGCPEDVLRGWNDFAHNLIYGGLMDEMFERAAQTDNLEEHGELVQVAHEYILVNIASLLHHLIILSPDGPYLMRTLENVHKLVPYGLVRQTLRVGNAATMINGMVRLVLTKLSLSTVTNWIGLTKGPDEGMNLLQQIISTVLWWDTMDLQRRVTKIEKQKDGLSKEQLQAIRSWIPKSRAEHEAARERSKSESKSIIAIIFETSSPPFAAKKLSNAHHGLAIDYLALHLSIRDRDELTKLLCKHQPDHLTAAIRDLVAAYDPIIRALHNAVDLSGTITDAEAFINDLIRLSKGVDRVNGGPSIKRSATNGTNTPVGYASGNESAGSGTETPRRFRNGNGRRTREAGNGNGGAEPPSVADFVALLRRHQASSHRFLHQVAKNGPEMAGWFRDYAHEALAEFRVGDPAGHGAGAGRMTPRLRELFGELPAEKRAQLGERLDRHAEYLATLESASTERLSIILNQRGSGSAPEPAHPEGHDLAGPGMYLARWQALLDTTLITPARPHGKVRTGKDPSVREMGRVGVDGVKRGIRGAGTTGNQHQLPNHVEVDELDVDGAAEGDGIRVGAPDMSVVVEALGEKFWDLLIEVRKESEAKKVGAKPEAKQEDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW13</accession>
    <name>A0A6A6NW13_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA ligase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_387001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW13"/>
    <dbReference type="OrthoDB" id="2160351at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF2">
        <property type="entry name" value="ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="7">
        <location>
            <begin position="372"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="660"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="728"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="775" mass="88616" checksum="23FE54981C9A0C3E" modified="2020-06-17" version="1">MPLHFGSFCDLLKDLEAHGKCGTPFLRKNRQDGERRIIRQWFRGHRAAIDKPDTNRAALLSSLFPERRKDRVYHMQVKRLSFVIARCLNLTTSKLETLNGWKAHGKGDLGDCIERVLRVHDKEPLLHPVTVEEVDEALDQLASRIKASSPAMRAHPCTKSAEEILKVILLRMRSVEAKWFVRIVLQNLAPIHFLLPSLLRFQDSFSAASQLLDGPLKKYPANPDPEPQKLFEIEAATLIRPQIGVQVGRPTFHKARSMGHCMRLVGDQVWSVEEKFDGEYCEVHIDLEKGRNCIQIFSKSGKDSTDDCKGLHSVIRDSLQIGAPQCTFKKRCIVVGEMVVFSEKEDSIVGFHKIRKHVTRAGRFININNDSPPDKSEHLMMIYYDVLMIDDESVMTQPYARRRDRLRQLVKKLHGRSMTSMRAVIDFSEENAQSRLTVQFSRALACRYEGLVLKPLNAPYFSLISDPDNWRWDFIKLKKDYMTDMGSSRDVVDLAIIGASYKAAEAHKTDMRFLKWTTFYAACLTNKDDMRFDSRPRFRITHEISLDDCIKPTDLKTLNEHGQFREEPLDEDGYQESFEIELDQTLAKNMTTAFKEPSVAEVLGSGFEKAPNQSFFHLRHPRILKLHWDHLADKARNAPPDEDLSQQTKEIVDRLVRQIRKESRRTGCSPSQLKRVPSPSAKRKSAETPTKISENTSVTITPSRASHTRDKQNSTASHKPRTRRTTIIRKDTCEKTPDQADGNPPDPSAATTLMQTSALRLLTDRPSRHSTNTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW52</accession>
    <name>A0A6A6NW52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW52"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="33513" checksum="337213C5396B5686" modified="2020-06-17" version="1">MASGPLTRVRDFFLGPPTAQTDDSEPDDSEPSEPSSPISEFLIVKWPPPKYSQDATVRAISSYYNFLSTILFDLEPEEIEWPPPSGWPQITEADGDYLNKNKTVIELLRHLPYFRQPPGDPYVWMQDTPVLCYQQGVGYADDYERTLFVDPYESEVPPHVVSLARGLRDAYYVMLDTERGVIYWGDGDEVPEDTTLITHEAVDRRHDWMNEPTWPIEDFFEMLKRKFRDLKWIAVNPTDIREIDDVYPVDEEYDLMRKALRDAGWPGDGEGGGWDRDAAAKRFSEIGEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW61</accession>
    <name>A0A6A6NW61_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_386800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW61"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="9">
        <location>
            <begin position="30"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="8">
        <location>
            <begin position="113"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="310" mass="35076" checksum="193051F90DB9C865" modified="2020-06-17" version="1">MASEAQSQTTKYDPNFTRSVVNSMGPKVPPRLRKVLDSLIQHLHDFARENEITVDEWMAAVELLNECGRMSDDKRNEGQLLCDVLGLESLVDEITYKMVTEANDLPTATAILGPFWRKDAPKRQMGDSIVMNKIEDGDHTFMYGQVTDYTTGEPIEGAELDVWHTAPNGLYEQQDPDQPDMNLRGRFTTGKDGKFWFYCLRPTSYPIPFDGPAGRMIQLMDRHPYRPAHIHFIIKAPGYKPLVTQIFDRRDKYVTNDSVFAVKDSLIVDFLPRNGDPKAEFELPYDFKLASFEQAKKSGVSGTTAPSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWB9</accession>
    <name>A0A6A6NWB9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_365023</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWB9"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF24">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="6 13 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025380423" description="ferric-chelate reductase (NADPH)" evidence="14">
        <location>
            <begin position="21"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="294"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2455767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="610" mass="68053" checksum="74CF71201DB969AD" modified="2020-06-17" version="1">MAFSTLRLLLLAGFVISALAQHGGGGHGEDGPTPADLKNVDFTKWLSWTWAVLAAFFIGFRLTIYLVNHIRHLACLTNDKQTYFATPDSLYGKLKRWFIVAPLWRTRHHREFRLSQAINIGTLPSRFQTFFLSGYVATNTAFCVLSIDWSGEYETVARELRNRTGVLAVVNMIPLFLLAGRNNPLINLTGLSFDTYNLIHRWIGRIVVLEAVCHTLAWMIPKVHTKGWAAVSGSVNHSNFIMSGTIGVVAFVFLLLQSPSVLRHAFYETFLHGHILGAALAVGAVWVHLKDRPQRSFLVAVIAIWVIERTLRLGMIVYRNVGSGGTKADVEVLPGDALRITLRVARPWRFRPGQHVYLYIPSIGWWTSHPFSLIWSEEEMPVEEVAGDIEKGFIPPSTMTTNVASSALEPHKTTMSLIVRRRTGFTDKLFRAADAKIGGKLTTTALVEGPYGHDESLQTYGTAMLFATGVGITHQVPHVRGLLRGYANGTVATRKVVLVWIIQAPEHLEWIRPWMMSILAMPHRRQALKVLLFVTRPRSTKEIHSPSASVQMYPGKPNVEALVDQEIESQVGAMAVSVCGTGGLADDVRRAARRRMTTSNIDFVEEAFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI6</accession>
    <name>A0A6A6NWI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_288592</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWI6"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19143">
        <property type="entry name" value="AKR_AKR6C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="345" mass="38681" checksum="7EAD1AD92833271B" modified="2020-06-17" version="1">MAFDPKNMIFRHLGPTGLKVSVFSLGGWLTYGGTQKGSIVKECMQAAWENGVNFFDTAEVYANGQSEIEMGNALKELGWPRDEYVLSTKVFFGTGRKEPNTRGLSRKHIVEGLKSSLERLQTPYVDIVFAHRFDYATPMKEIVEGFTQVIRDLNLAYYWGTSEWSAQQITEATLIAERYNLIAPVAEQPQYNALHRERFEVEYAPLFKELSYGTTIWSPLASGLLTGKYNDGIPEDSRFAAHQGWFGDTIKELKTPEGQAKLDKIRKLTKVAERLGGSVAQLALAWCAANPNVSTVILGATKVAQIHDNCKALQLVEKLTPDVMNEIEEIMQNKPKGPPTWGRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWN8</accession>
    <name>A0A6A6NWN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="7">1.1.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_348228</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2</text>
            <dbReference type="Rhea" id="RHEA:21252"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16782"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the L2HGDH family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.2" evidence="7"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWN8"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF4">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="10">
        <location>
            <begin position="33"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="418" mass="45322" checksum="0B3CF934ECBC3840" modified="2020-06-17" version="1">MLFTAGIFRSARVRGARAFSVSAARRDADFTHAVIGGGVVGLAIARQLQQREGVSTVLIERNELVGMETSSRNSEVIHAGLYYPADSLKTSLCLKGKPMLYDFCATREIPHRNCGKWIVAQDSGQTEALQQLHEHASSIGVPTHFLSKDEAKRREPDVRAEAAVLESPTTGIIDSHSLMQALHADFEEAGGATAMRTQVSRVEPADAGRSGWRIYTTDPGAGDKAEGGDEAEPVTVEALVNSAGLWAISLSNTILPPDRHITPQFAKGSYFSYASSHPKPQTLIYPAPIPGHAGLGTHLTLDMTGRIRFGPDVEWLPEGMPPSEFDYAPNPERLSLALDDIETYLPGIDRSAVDLDYSGIRPKLSRAGSVAKKGQPFSDFYIKKEEGFEGFVNLLGIESPGLTSCFAIAELVEKLLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWP5</accession>
    <name>A0A6A6NWP5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Terpene cyclase/mutase family member</fullName>
            <ecNumber evidence="7">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_70397</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="7"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWP5"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000250">
        <property type="term" value="F:lanosterol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02892">
        <property type="entry name" value="SQCY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000003">
        <property type="entry name" value="Terpene cyclase/mutase family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002365">
        <property type="entry name" value="Terpene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01787">
        <property type="entry name" value="squalene_cyclas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF20">
        <property type="entry name" value="LANOSTEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01016">
        <property type="entry name" value="Prenyltransferase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01074">
        <property type="entry name" value="TERPENE_SYNTHASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Squalene cyclase N-terminal" evidence="10">
        <location>
            <begin position="97"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="9">
        <location>
            <begin position="407"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2455683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="718" mass="81489" checksum="107483EB0AEE6E5F" modified="2020-06-17" version="1">MAPGAHPLGKVNGTTAEKNDGVAGGGATTAGTTADEKTDYSRWRLKVDDGRQTWEYLETDEEMKAWPQTVADKHHLGLPTGLPDLPPAKTPLAAASNAMSYFSRLQLPEGNWACEYSGPMFLLPCLVVAWYVTETPVPAPKRVEIKNYLFARQHPVDGGWGLHTEGDSSVFGTSMNYVVLRLLGADAEDPRMIKARGTLHKMGGALNGPHWSKFLLAVLGVASWDLVNPVPAELWLLPDWVPFAPWRWWVHMRQVFLPMSYTYSKKWSYPLTPLTAELRKEMYVQPYESINFASHRNDISPLDNYHPKSWVLNTINWVLVNMWNPYLRTNYIAKWAEDWTWWLIQREDENSDYADLGPVNAPLNMLCCYIAEGPGSRSVRRHRERMDDFLWVKDEGMLMNGTNGVQIWDTSFFIQAAISCRFQKDPQWRPVLVKALEFLEAQQFREDCADQERCYRHPRKGAWGFSNRVQGYTVCDCTSEGVKSIMLLQNLPGYPKLLSDQRIKDAIDVILTMQNAGTGGCSSYEPRRGSEALECLNAAEVFGNIMVEYDYVECTTACVQALSLFSKYYPEYRTAEIRRFNERALAFIRAAQRPDGSWYGAWGICFSYAAMFALEALGSVGETYASSERVRRACAFFLDRQMPDGGWGESYHACETGVYVPHERTQVVQTAWVCIALMEAGYPDKEPIQKALRLIVGRQQSNGEWLQEAIEGVFNKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX50</accession>
    <name>A0A6A6NX50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX50"/>
    <dbReference type="OrthoDB" id="1065058at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.450:FF:000001">
        <property type="entry name" value="SDT1p Pyrimidine nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="235" mass="27056" checksum="B319670CC50FAC28" modified="2020-06-17" version="1">MTDTAELPVLFFDIDNCLYPKSTKVYELMSNLIDKYFETHLALSQQDAYTLHQKYYKDYGLAIEGLVRHHKVDPLEYNRKVDDALPLEDVIKPDPALRSLLLSLDRTKVRCWLLTNAYVTHGKRVVKILGVDDLFEGITYCDYGAEKFVCKPNPEMYEKAMAEAGVNDRGKCYFVDDSGSNVKSAITFGWTAVHLVESSEPEPSHKMGQYQVRHLEELRQIFPQFFNVEGKENRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX58</accession>
    <name>A0A6A6NX58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-structural maintenance of chromosomes element 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_287943</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the SMC5-SMC6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NSE4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX58"/>
    <dbReference type="OrthoDB" id="361242at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027786">
        <property type="entry name" value="Nse4/EID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014854">
        <property type="entry name" value="Nse4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08743">
        <property type="entry name" value="Nse4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-structural maintenance of chromosome element 4 C-terminal" evidence="9">
        <location>
            <begin position="324"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="48063" checksum="9484A9833E40F6A4" modified="2020-06-17" version="1">MAPPARPSGGSSNTSGDKRRRLGERGIPTATRTASIGPDPNAIVDQQFYDPDQDPEERRRIIQHMRGLRNEIRDRRDELVASPGNHDLLRQMLERSDRDMNQVKQTSDATMESANFLSLVDISVRKANAEVDGNLGVDLDEFIGKCIGFMRRGGPPPADTSPAHGEEGDEAATQARRHGSSRRSVATEGDELDDDDGDALNWGAFGSRACFPGNLRPPVPAFLLGPLSVQKRARQATQRRARLGRPEGPTSRPEDLKASDIERNENANITAFCVKVRQRLKSHIEDAMEAVEDNLEDDMTEEQEKELLRRYRVQSTDGESGLVGFFDFVINPKSFGQTIENMFAVSFLIRDGNVAIEEDENGLPLLRPENPRTIEEQRREEVSKHQAIFSLDWETWQNLVQAFDIREPIIPHRNEEEGRNVTGRGWYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXA6</accession>
    <name>A0A6A6NXA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_287557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXA6"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000043">
        <property type="entry name" value="General stress response phosphoprotein phosphatase Psr1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="1">
        <location>
            <begin position="4"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20499" checksum="2967C1F3C4828E66" modified="2020-06-17" version="1">MRPEHRGRKCLVLDLDETLVHSSFKILHQADFTIPVEIEGQYHNVYVIKRPGVDRFMKRMGELYEVVVFTASVSKYGDPLLDQLDIYGVVHHRLFRESCYNHQGNYVKDLNQLGRKVEETIIIDNSATSYAFHPQHAVPISSWFSDAHDNELVDLIPVLEDLAGPQVRDVSLVLDVSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXR4</accession>
    <name>A0A6A6NXR4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_55168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXR4"/>
    <dbReference type="OrthoDB" id="2851338at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27709" checksum="3E9C94696B32A2EC" modified="2020-06-17" version="1">MPEKPSPYLLRVNSRPSRPDIGDDLWTEFCTKERLPDLVKSGVATRAAFYRELHNFPPLSGVRPPKDEAEKSRNFLAMCQSNHQTPIDTEEYRNLRLDSDLLPEGEVKSMGDYDARNFKLIQNFDPKGVGVQPGKYLLTVEMSPADESTYHMFYEDEHLPLLTKVPGYRRTLRYEMGPRDPILTPKRDLPGFFVGHEYDSLDGLAGEEMDAAMSTDLAKTVRMNSMAVIWRCWELIEGVGFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXY6</accession>
    <name>A0A6A6NXY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_257459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXY6"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="32959" checksum="FC8E4D85E3483F71" modified="2020-06-17" version="1" fragment="single">EPETHTFTQTKGHTISYCIYGVAGDTDPPPPTIFYFHSHPSSRYEAALLHPTAQRHGLRIVAPDRPGMGESPLDRSRRLLDWPADMLALADHLDTRRFGVVGTSGGGPYVLACCLRLPRARLAGAGVVCGLFPLKLGTSGMMWETRLMLWVAGWAPSLVALGLDFALGKVARDREHPEAFEAAMAKAMESRPEVDRAVIQENAGGFRDAMLENFREALKHGSQGAAYEAKLFSGDWGFKLEDVKMAEGTLVLWHGEKDVNVPVAMAQKAAGLLDGAELRLSPDEGHISLPVNKTDEIMETMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYP3</accession>
    <name>A0A6A6NYP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase (quinone), mitochondrial</fullName>
            <ecNumber evidence="5">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_45006</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(S)-dihydroorotate + a quinone = orotate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="5"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYP3"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106430">
        <property type="term" value="F:dihydroorotate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000242">
        <property type="entry name" value="Dihydroorotate reductase PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="137"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="483"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="422"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="534" mass="58133" checksum="BE1322629DD7A0D5" modified="2020-06-17" version="1">MSRAQIGRHGLQFFRLARPPHSLHFRPHRFQPTLQVHRRPASTTSSETATDARSLVTRLKNLFLGTSLVLFAGFGYLYITDTRAAFHRWIIIPLLRTVYSDAEDAHKAGNRALATLFDFGLHPRERGSPDSTSDLGITVFGYPLSNPVGISAGLDKNAELVDPLLALGPAVVEVGGVTPLPQDGNERPRVWRLPSQRALVNRYGLNSDGAEAVAMRLRQRVRAFAYHNGFGIDEEAERMVLDGEAGVPPGSLASGKLLAVQVAKMKSTPDADIEAVTADYVFCVEQLAKYADIIVVNVSSPNTPGLRGLQRVEPLTRILTGVVDAAKDVKRKTKPAVMVKVSPDEDSDEQVLGICDAIFDSRVDGVIVGNTTKSRPDPLPKGYLLPPKEANYMQEYGGYSGPQLFEQTRDLVKKYRTFLDQGHRSLTSPPDPGYSASSFPDNPEVDVPPKVEESKPVGDQKASDDADVARLLPAKPEIAPKVIFASGGITNGDQAHEVLNAGASLAMVYTAMVYGGPNTIRAIKDEMREHLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYV1</accession>
    <name>A0A6A6NYV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL Lipase/Acylhydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYV1"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="28646" checksum="0908FF1927317E4A" modified="2020-06-17" version="1">MSSPYDQILLFGDSILQQSCNQEGGFGLTPALQDAFIRRLDVVNRGLSGYNTQQALKVLAKIIRPPHQAKIRFMILLFGANDACLPNSHTKQGIPLGEYRENLKTICTHPAVEAHKPRIVVMIPPPVDEYALAQWDGSSDGHPTRSAERTKEFARAAREAARELQLPILDVWSLLMSRTGWKEGQPLPGSKDNPKVTLLDEFLYDGLHLTSKAYKLVFENLMSIMESQWPDQVPERLPFVLPAWDDGDKWRASSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYY6</accession>
    <name>A0A6A6NYY6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_47019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYY6"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="240" mass="25212" checksum="B1E3711D22D3646D" modified="2020-06-17" version="1">MPGPVAELGPLHRVDGSAAYSHAGYNVLGAVTGPVEAQRRDEIPDEAAVDVHVRPATGVGSIKERHLEAIVQSTLRHVILVHQFPRSLVQVSLQVLSVPDTSLMAVPLSSRLTTLALLPALLQTAMHALLSAALPLSTTFTSTLVCVTRGADGGGAIRASPDPECLADAASAHAVCYSAGGELLMDMSEGDFDVDEWDAAMGVGRRICCGEKGGRGGDAVMRDEESESLQDKLRKLVAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYY7</accession>
    <name>A0A6A6NYY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_347239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYY7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="17065" checksum="1066420F06D2A4C4" modified="2020-06-17" version="1">MQYVLATYSTYLCVYKRPPLVVVPPLRVPSRSSRAAPQSLFRFCGSRLVRRDGHALCREGVRKWIAFDFFFFPRTCMYAVCRLKLSSGALQGPEVRIYLETGRRLAVRVRGIGPSGCLAVAGVGEANECRFDRFGREWPQVVRILRRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0A0</accession>
    <name>A0A6A6P0A0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_386020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0A0"/>
    <dbReference type="OrthoDB" id="4152607at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="193" mass="21921" checksum="C545AA7BB1546A14" modified="2020-06-17" version="1">MATGTNMLSAEKTTLPFQPDPFQLLQMPLGTFIKDPEILDVLSPHSEDRDQKNLAYLLQLRRGSSQWNKWAYRVVELRAQFKSAQNVALATHREVRTAITIAERCFDDRWALPVVAILIALKPRTDNDTIIRIAFHPSEEVQSISLQDIKIDGDRLPEVKQSQSMLNDVHRRFSGRDIGLLNNPFKNGTSLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0B5</accession>
    <name>A0A6A6P0B5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_321561</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0B5"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="353"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="46"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="487"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="684"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="714" mass="74725" checksum="226B73749BC8D4D8" modified="2020-06-17" version="1">MASALWAVADIIKREAEDADGEDTDAGQKEIFASWSLFILIILLIIALFTSYLLQTRRVQAVHETVLSIFAGMVVGLILRLVAVSTVLEAVSFDYQFFFNLLLPPIILASGFELHQGNFFRNIGTILTFAFAGTFISAVVLGVILYLWTRLPLDGVDITFVDAASVGATLSATDPVTILAIFTTYKVDPKLYTVIFGESILNDAIAIVLFETAQKYKEGEVGGSLTVFSLFESIGIFLLVFFGSLMIGLIVGIATSLLLKFTYVRRFPKTESCIIILIAYASYFFSNAIHMSGIVSLLFCGICMKHYAYHNMSRRTQLTTKFIFQVMAQLSENFIFIYLGLSLFTDTALEYKPLFILITVLGICVARYCAVFPLARAVNFVLRYRARRRGREPAEEMPYSHQVMLFWAGLRGAVGVALAAGLTGPSSYVLRATVLVVVVLTVIIFGGTTARMLEILGIRTGVVEEIDSDDEFDIEVVAGGGGGFFSRKQGQGFGHTPRPSSNGFALSSVSAGGPNANKRPSFSAGGAGSTSYSSGNVNGGTSPTGIRPALSTRRPSSRARAAARDGADQGLLSSGSSADDDFDDAGDLDLPPASSAAVAGRTPSPFLSAAGTPEPTAAAAAGTVAHAGEGSSAHHGAVARMTAAAGAMGQLISGLSEDPAQAFRKIDEGFIKPTLLLDASKGGGGGGAGGGGGGSGNGGGGGGGGHHGSGSGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0D2</accession>
    <name>A0A6A6P0D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_345232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0D2"/>
    <dbReference type="OrthoDB" id="88561at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="12551" checksum="EE907C6F412F4AD6" modified="2020-06-17" version="1">MIDTTVLKDTGRFLKLNDLIEELSLTIPNPAVQHIQGAFLCLHRIPPEAIVERRNPKEVDEGQQDRREERYCEELDSGDYLAEYSGSEREAMEANYNTTFESNMEDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0G0</accession>
    <name>A0A6A6P0G0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mu homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_37599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0G0"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="168"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="436" mass="49167" checksum="3DFC80A2BD3AFB7E" modified="2020-06-17" version="1">MLSGILIFNQKGENLIFRAFRNDCRPRLADVFRIQVISNAQVRSPILTLGSTTFSHVKHENIYLVAVTKSNANAALVFEFLYRLVALGKSYFGKFDEEAVKNNFVLVYELLDEILDFGYPQNTETDTLKMYITTEGVKSERAMEDSSKITMQATGALSWRRADIKYRKNEAFVDVIEDVNLLMSATGTVLRADVNGQIIMRAYLSGTPECKFGLNDRLTLGEDGLAQPSGNRAGTKATRAAAGSVTLEDCQFHQCVKLGKFDTDRIISFVPPDGEFELMRYRATENVNLPFKVHAIVNEIGKTKVEYSIAIRANYGSKLFATNVIIRIPTPLNTAKITERTSQGKAKYEPEHNNIVWKIPRFTGQSEYVLSAEASLTSMTNQKAWSRPPLSLSFSLLMFTSSGLLVRYLKVFEKSNYSSVKWVRYMTRAGNYEIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1F2</accession>
    <name>A0A6A6P1F2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_286069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1F2"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF11">
        <property type="entry name" value="HET-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13694" checksum="C935008853F44EAE" modified="2020-06-17" version="1" fragment="single">MLTESTWELAFRSSRWFTRGWTLQELLAPSIVEFFSQEWKKLGDKISLKSQIHKITSIPYEALEGAPLSQFSVNERLSWGKYRETKLPEDRVYSLMDILGVYISPFDGEGAGRAFKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1S7</accession>
    <name>A0A6A6P1S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_15426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1S7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="52181" checksum="768967CFCF0BFA9A" modified="2020-06-17" version="1">MADGSWLADDPMEWSEDDYSSLFCSRNVLGYDAGTTGNHSHHEAMPNSFEQPLAIDPSTLYPPGLDASNRQASFGAPSQNNDSTIAHSDRSRTMPGNNINTRETGNLALAQSIPSNLDDLPSNAFRFENDSSPGPNDPTLASNLPPQSTTVQFWDQLMEPSNVSTTNNHPNSRIFRAGPDSGLSGTFHRNSFLSSPKGNLDTLDPFAFVPVVGWRESSTSAIDLQFQENSACFSVSQPLDQSLLVASRPPFFPQQQSLALNSYPLLSFPTSHWTSVGTLAYPYNSIASPRQPSMSIPNAPEEIPQDMVSYPLLGLPGINMDPLQNQNIGGPQTSENLIADSNVPDRSVPSLGEETEADARQNPISTAQQRCSSQGTSRRIEDENRPKRTLGTKETFAVRKFHKTQHGGGFGLFVLANRPQRASRPRSPQENENRKKLKEVGGACLLCKWDGKRMCDIIYSYIPKRNILLLRTVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Z6</accession>
    <name>A0A6A6P1Z6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_371351</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Z6"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="144"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="444" mass="50680" checksum="B28B6224664E6A90" modified="2020-06-17" version="1">MYWKSYKIKANAMTRELYVLLQDSKGSCRLLSSFAEDVQDPECLEKDAIHEAVEEAWIRGAYTPQGIKPHSILRIKSSATGLLGVLVNNLDDYNTFYSYLKPLDQYFNKSVQGEGGYLTPPSEVDHIEYRTVTYVRAFDSYRSTSRTAKIGSSQDIVVYKGISFLDFLAFGEGRFREYVNAIYREHHLISSVIPPHPNIMAAPKAYVTLDSTFPDGSTVPRICGCIFPYYNNGSLAAVLNRSVEERTRISLKRKAKWCYQLVSAMAHVHFVASAWHQDLKPPNILIDDNDDLLLIDWEQVGQGGFFIAPESDGTFDVSTVEEDGGKQKLVYTRYEGPRRVNNTLSHPEWNVLPTWKEEHPKAVELAEVHSTGATLYLLLEQVRLVHVEGVSDYSAEEVRWSEWSDDIPQSWKESITKCRMLDPNERIGMMELLEFWKTEYGKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P292</accession>
    <name>A0A6A6P292_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P292"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="13226" checksum="1402E0E5478D7E16" modified="2020-06-17" version="1">MSTSPPASPPPFLLPLSPPLTSQPSSAASTITITLTITLSPSPIPSPSPSSAGATVAASTTSAGSPSFRSAETASARAIALGVGIPVGAALLALLAFVAWRAWRVVVAREERLRRGKVVGGRVDGDDGGGVGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2F3</accession>
    <name>A0A6A6P2F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2F3"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="298" mass="32265" checksum="EFDFC751295F99B2" modified="2020-06-17" version="1">MAEALGITASVIAVAGLAYSSSQKLYQSLSDLHEAPETISGLKTDVGTLSDTIHSLKQKLNDEVSDDSLSDEQKANLTQIQPALKACCDACNQFQDKIKKLTSHSKDGTISRRDKAKLLFEKAKIGAFQSQLNSYKSTLAIALEFSTFKTASDNFKATQELEQKIEDTTALLTGQMQGLQIGLQAVLDAGSQNNELVQDDSQDQLAEIRQSQILGAIEQQNVALNHCYRACMAAFKETTKATGHEYKYVKASNQARLLMGDLGNVEGGAQHSFTNLEVTGGWVVAGNMEGASAKDFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2S2</accession>
    <name>A0A6A6P2S2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">26S proteasome-like protein regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_284224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2S2"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="34"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="331" mass="37113" checksum="BC700C017B7C337C" modified="2020-06-17" version="1">MERFGQLLANAQRMGGMSAGPAQDTNLIDNSETVHISSLALLKMLRHGRAGVPMEVMGLMLGEFVDDYTVRVVDVFAMPQSGTGVSVEAVDPVFQTKMMDMLRQTGRPETVVGWYHSHPGFGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPQTLMMGQEPRQTTSNLGHLNKPSIQALIHGLNRHYYSIGITYRKTGLEENMLMNLHKHVWTEALEMNDFREEGDRNRERLKRLVGLAEGYEKRVKEETELTKDQLKTRYVGKVDPKKHIEDVGQQLIEDNIVSVSRQMIDKEASVPKGKTPTNGVPNGDMEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P359</accession>
    <name>A0A6A6P359_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_385439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P359"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1300.10:FF:000003">
        <property type="entry name" value="Amidase signature enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF10">
        <property type="entry name" value="ACETAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="64"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="210"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="570" mass="62657" checksum="EA09E1FB04BFA469" modified="2020-06-17" version="1">MLYPFDYFQHRADCKRKQSERASKIATLPRPYLLPLSPAERTILGKPIAELVQDVHKQVTSPLDVLRTYGKVAIKAQKETNCLTEIMFPEAEDWINDGGINLKGPLAGIPVSLKDSIGVAGFDASVGYSCHTGKPWKEDGTLVKILKDAGAVPFVKTALPITLLSFESTNDVWGRCNNPHNHKYSPGGSTGGEGALLAFGGSRIGIGSDVAGSVRAPAHFSGCYSLRCSTGRWPKMGMTTSMPGQEGIPSVFSPMARTLDDLAYFTRSFIGMQPWRYDHSVHPLEWRASVEAEFRDPARKLRVAVLRSDGVVDPAPACARALQSAVAALAAQGHDVFDVAPPADAPPYDALVLAAQLLNADGCRTFRSFFRAGERDDPGAAQMGFYMRLPRPVKYLYYLWVKYVRRDPLWAGLLAGWHEKSAFENWQLVAKREAFKAKWHAWWEGEVKADVLLTPPNATPAVPHGGMKQAVSSCGYTFLFNLLDYTCGILPVTHVDRVLDQLPAGFDIKKLNGVAQGAYVHYDPIKMEGLPVAVQVVGQRLTEEKVLAIMERIEDALEKEGGKYKLLEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P370</accession>
    <name>A0A6A6P370_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_284825</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P370"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF17">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602402-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="504" mass="57222" checksum="516C192A2FD5F732" modified="2020-06-17" version="1">MADGSRSHFYLILLSVLAVCSASYFAFTGITTYFRRRQIKKQNGCEPPPRYPHGLLGLDFIRATLREAERKKMLDTSRARFDKMGGTYSATLSLQPMIFTHEPDNIKTVLSIKFKDYNLGNRKNSLGPLLGEGIFTTSGEHWHSSRSMIRPNFARDQVADLGAFERHFKLMLRKIPRDGSTVNLQDLFFLMTIDSATEFLFGESVHALKADASTTNGFAEAFNHAQNMAARRIRAGKFAVFFHGKGETEAIKFCHEFVDQFVDQAVEYRRKLDEEDKGAVDEKYVFLYELAKTTKDKKRLRDELFNVLLAGRDTTASLLSNMFFEIAKRPDIWEKLQAEVAQLNGEIPSYETLRNMKYLKYCMNESLRIHPVVPLNSRLAVKDTVLPRGGGADGKSPVFVEKGALVSYSVYSMHHRKDIYGPDADEFRPERWEALRPSWEYLPFNGGPRICLGQQYALTEAGFVTTRILQEFKGIESRDPGPWVESLSLTLSSHGGTNVSLTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3D5</accession>
    <name>A0A6A6P3D5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_420955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3D5"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036149">
        <property type="term" value="P:phosphatidylinositol acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="5">
        <location>
            <begin position="128"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="475"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="579"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="501"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="594"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="746" mass="80590" checksum="9FAB08E0018D1E0C" modified="2020-06-17" version="1">MMAPNPPQGNGDAQGLLAAASNMDPKAVAGQNANMSPMDRMISAGSTLLSGAMAISASQFMGAPLKLISEEYYKSYMSITKQAFAILITTITQMWSPTVVRVTGDASMKDQLQQRGDGALKCNFPSRILLMANHQLYTDWLYLWWIAYTNGMHGHIYIILKESIKNIPIFGWSAQFYNFIFLARDWKKDKPKVRKCLQQLNNNDPMWLLIFPEGTNLSKSTREASRAWAQKNGVEDMKHQLLPRTTGIQFCLQELRQTTDWLYDCTIAYEGVPPGQFGQDIFTLRSSLLEGKPPKSVNMHWRRFKIADIPVDNSKAFEVWLRNRWREKDYLLEYFQRTKRFPSEEFWKTTTTTGANGGARVAQTGIDKRKAVKPAPYVETEVKSGSWEEFLSLFAPITAFIAVLFLFYSDPKHLLNAGQNGANDPAAQQAQLIQSMMQAGEPPSDEKKKQALLSAIGASQSNALLKSAGAAAGRGDFGTATPSPSTTKANSRGQPLKLRPAAPLRSRTSSSSLSSSAAPHAATAGTPVAKLPPEQIEQIKGMLRQRAASELGSVRSAPVKTAQQRAIGAAATRAAAAGNARRASVQAQPRGNDKATAGGKGTAASTKGSVAPARSTAASTKTGVVQGGPKKLGGVKAPGNQIKGGAQRATPQHVTAAQKGGGGGGGYAKTPIGTVKKPPTAQTAPGQQKKKVQQGQGQGQAQKKKEIPTIKADPKVLARVPIKEKEVPNIKVDEKTREKLRAGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Y3</accession>
    <name>A0A6A6P3Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ras-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_209939</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05137">
        <property type="entry name" value="RasGAP_CLA2_BUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="729"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="615"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1137"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1209"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1282"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1338"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1348" mass="149438" checksum="E8E408429FBDF5FA" modified="2020-06-17" version="1">MERERLPRRRPPAKSVSLDSHSSQTARDDPPVPPTRATYSTIRTVTPESMNENGKPRPQYPRPEDANTMASSPPVSPRTKVESPRAANPRAFLARAGSSEEQVLRSGKEAQMRPRTRTMDERSQERSTSSLFIKSRHRIGSVHSTSSASYGGLDDTVTSIGHPLTISPTPQTTPRPSAVGRNKLAKQQARADPSPLQQRVADPDAMISLTLPSNVRKTYQLMRSTCGVMSGMLAFRRGDSDRWRLSYCEINEEAGSLVYEPREDSTYHRTLIPDLRGCQVKVAYDAVSCTPYLEVSLHNSSLEVHLRPPTEEHFETWYAALLCWQPIRPKGIMNKMAKPQGPRRLIDSRRHSEVSLSKEAPIIKVGKMIFWDPDVPFGAFGNGANQFAGRTPSYSTHHNFRSRRWRKVSCTLRENGELKLYADTDVTLLAVVQLSQLSRCAVQRLDPSVLDNEFCIAVYPQYPSGADNVSLLRPIFVSLESRVLYEVWIVLLRAFTIPQLYGPKQALQEDLSSSQSFATVDMFRMERSLYVKVIEAKLLPPVSPHSTEPQPTPGSRPVSASAYHRNPGYYIEILLDSETRAKTTPKYEPTTPWWREEFKFSDLPATLATASIVLKKRPPRPPPHNHHTEGKLTKHESLESNELSGSYPTFDVTCGRADIYLDDLEPGADVEKSWALLSPQGHSIGEISLRIRTDDAVILMAMDYQPMSELLHRFTNGLTLQIAQILSSQLKDLSECLLDIFQVSGEAGEWIMSLVEEEIDGTLKETPVSRLRFSRRLGSTESGDAFSSTGERELIVRDYGKSAMLEANLLFRGNTLLTKALDMHMKRLGKEYLEETLGEKLKEINDKDPDCEVDPNKVRFHHDIERNWRRLITYTEEVWQCIYTSASRCPPELRVIFRHIRACAEDRYGDFLRTVTYSSVSGFLFLRFFCPAVLNPKLFGLLKDHPKDRARRTFTLIAKSLQGLANMSTFGAKETWMEPMNRFLSSHRDEFKTFVDGVCSISSDRAPSAIPPSYSTPLQILTRLPPTSREGFPSLPYLIDHARSFANLVNLWLEHAGDGAYNLQTSDGELLRFHNICEHLQARTRDCLERAERAEQPSSSLNMQWEELLREMTKDATLEAEEEVTAEEAEPRDSRTRAQSTSAPTSATSRGSGSISGSSPPPLEMAWRPKPLASSTAAAASAGSSPGAWPVSASASRTARALPKQRAHSPATSSSTTTAATTPTSRGPRDYSPSYPGGHAAGPSNNGEGMTPPSSATAMEGSTVLSDAGGSDAESTTALPRMDSRERDSSRGRGRLGGFVPSLAMGRGRRKKGKSKGDEMLSVGAEWEPGPSADGSGRPDGGVAGAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P422</accession>
    <name>A0A6A6P422_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_385207</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P422"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="112"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="377" mass="40736" checksum="F2B217E0D9B71AB9" modified="2020-06-17" version="1">MPRLTSTFVYPPDPPKTPPIKLPQNTPRAPPKPWSHHVTVDTILAALNRTILHPFVAWMVPLTLRAQLVDYDHPWMRAAIAWAALLTLLFVVDTISRRVAFGLPRDVELEEEVVVITGGAGGLGALIAEVYGLRGVSVAVLDIRDEKEVGGALQGVTYYQCDVGDRQQVEKTAEKIRKELGTPTILINNAAIMHGKSILDLTHEEIEKTFQTNLLSHFYTIKAFLPGMYAENRGTIVTVSSVLGRLPGAANLSAYASSKSGLLALHASLSAELAASAHPSAPYIKTLLVTPGQLATSLFARVRSPSNFLAPVAEPVDVAREIIRAVDNGESGEISVPLYARWVDWLGVVPVGVRQGLRWWSGVDAAVKRGSEGVGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P449</accession>
    <name>A0A6A6P449_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_283831</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P449"/>
    <dbReference type="OrthoDB" id="2015537at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="39"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="47296" checksum="157B6BB3CD37B531" modified="2020-06-17" version="1">MARKHPFDINTCARHNILSLEPYRCARDDYKDDGTNILLDANENAYGPGLPLDANGKLVDANKGINGLLDLDLRGLNRYPDPHQEELKSLLCALRNTGTHRDQALAPANLFVGVGSDEAIDALLRAFCMPGHDKLLTCPPTYGMYSVSATVNDVAVVKVPLREKNFSLDVPAIHAALSADPTIKLIYLCSPGNPTGTILSKDEINEVLSHPTWNGVVVIDEAYVDFSPPGSSLAQRVLEHPNLVVMQTLSKAFGLAGIRLGVAFCPKPIARLLNSLKAPYNISSPTSHIAKAALTPAALKVSSGYQEAILQQRDRMVRELPGVHPSVGALRGGLDANFLLVEMLDQPSGKPSNIVALKVYEQLAENRGVVVRFRGKEHGCLGCLRITVGTEDEVTRFLSELRSVLNSIYKEEDVASVLDRKKEEQEEVKANDVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P515</accession>
    <name>A0A6A6P515_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_339709</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P515"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07102">
        <property type="entry name" value="ALDH_EDX86601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000012">
        <property type="entry name" value="NAD-dependent succinate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="468" mass="51081" checksum="C797D86203AC3AC5" modified="2020-06-17" version="1">MSVEKLTTISPVTNKPVVTRNGLSDADLAFLPQIATDAFHSFRGTPLADRQAIVAKALKLLDKRQHELARDITEQMGRPIAFTAKEITTAVARGEYLLKVSSEALATADGEPEKGFKRYIKKVPVGPVLVLFAWNYPYLILVNSLIPAILAGNSVILKPSPQTPTVVEHVQQIFSDAGLPKNVIQYFHCGSMTQIETMVRNPLIRQVCFTGSVAGGLAVQRAASDRVAVRVGLELGGKDAAYVRKDVDVKWAAEEIIDGAVFNSGQSCCSLERVYVDEAIHDDFVAAVQDVLKGYKLGDPFDTGTHVGPVVSKRAMETIKAHIKDALDKGAKDMTPQNESFRNPPADGNYVAPTLLTDVTHEMTVMIEETFGPVIPVMKVRSDGEAVKLMNDSKFGLTASVWTKDVPAGEELLDSIEAGTVYVNRCDFPSPDLAWTGWKDSGKGQTLSKFGFDQFFKLKSVHVKNYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5B0</accession>
    <name>A0A6A6P5B0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_339430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5B0"/>
    <dbReference type="OrthoDB" id="4331875at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="181" mass="19712" checksum="16F7A2BA5417C333" modified="2020-06-17" version="1">MLKTLISHKYSNSIPAFTMIKLPVVLTTVTLASAKLLSRQDVGDDYIESVCSPNITSPSPESIPPCIQVTTIQTDCETLDEIDSYQVCMCTTNAFFESWSGRMDCLYVHGAHSERDVTNWENILSSVSEDLCTGTPTASWPAIFSSVAEAATPVSTGATVLSDQYPSQTDVKVQCCKRKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Y1</accession>
    <name>A0A6A6P5Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_338172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Y1"/>
    <dbReference type="OrthoDB" id="242766at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070131">
        <property type="term" value="P:positive regulation of mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="172"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="466" mass="52516" checksum="C654C2BC9231FDFB" modified="2020-06-17" version="1">MLPLRHHAALRSVIRFIRPAFPHVRVSPFQGLVAQRKKFSSQTWPQSKQEETSINEPKDGPDDPAEKKQKASRSLASKTSLRRVALAAERSREGIIRRKGKDMFIAPDVEKMVVTAYCAADQYDPSKVADLLRKDGYQLDPCRTGLYPGVVHVQTSKIASRNGADPSVFGDIFVFPETGSVVTWNVSSRVAFHLLNNVLPGALPNPKARLSEHEVEDLDYLEDPTQEKSSIVGDTILLGTKVATQGLHSRDPTSTSSDGSAVYQNPPPGHEADTVLIKMSFSSGLARSTKLAVLERILSSYFDWIQSITTALSRSSRLPFTRKVVLRKIGELLTIRAQLNLYSELTDRSPDLFWDSRYELGLEGYYDKIGNALDVNSRIKQLNERMDYAQEIATVLREQLSEEHGTFLEQLIIFLILVEVIFETYHIVKESYEKWDPDGTENLLREYLLHELRREDVGQADKSSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6S1</accession>
    <name>A0A6A6P6S1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_282100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6S1"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="223" mass="24223" checksum="36194775706D4102" modified="2020-06-17" version="1">MLETVEIAYVTPAPGANFADAESDAGKALALVNETSSKQPGCKANYYGQQVEHPELLQLGIVWTSVDAHKAFTESPDYGAFLASVQPVVAGPDAIRLFHVELATPFSTAASAPVVEFLTCYFPPSYSNAQFDAVWDSFASELMTTADGAKGTVGGWVVEELEHKSLEAHGGKGKAFVAAIGWESVEKHMAYRDTDKFKEIIQPFRKEVSGIEMHHVELKLWQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P771</accession>
    <name>A0A6A6P771_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MICOS complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P771"/>
    <dbReference type="OrthoDB" id="2399148at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019166">
        <property type="entry name" value="MIC26/MIC27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033181">
        <property type="entry name" value="Mic26_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268:SF1">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09769">
        <property type="entry name" value="ApoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="248" mass="27110" checksum="BE345FD483D668F6" modified="2020-06-17" version="1">MAFRSLMRQRYAAPLAATLGAAGLALYPRRYVHAEAPPSDDDGVERRPIYDDKPSLYPPPESSPSDNPPPPSPSTSSPTPTDRLTVHIKRARLFLHGHAVVAEDKVNELMTSFLNLESSFTSTIAGLAPPRESGERLLPNGIYVLVAAMAGSIVTRNRNIVLRASVPVAVGVGAAYAVLPITMRNVGDLVWTYEEKYPALAENHIRIKERVQRFWETGKAHTAMTGAMIEDKVSEARGAVEDWVKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P783</accession>
    <name>A0A6A6P783_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_193774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P783"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025597347" description="Secreted protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12997" checksum="12F63C54C8A022B3" modified="2020-06-17" version="1">MSLTNSCMLLETVLCFCANEWAGPLRPSARSRCRQSETHPSGRSSRVRAWCGEGRPVARQLRRRCHSLRDLRPASPKRETNPREMYRAEKKKREKGNCNRTRRRRTVGQVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7E4</accession>
    <name>A0A6A6P7E4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_419541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7E4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="12371" checksum="5A6794446935880C" modified="2020-06-17" version="1">MYGNIGAERVDEVLEDSGRDGERADMLLTGTSSSDFQALEEEERRAVIIEIAAAMRPAWATFLAAGSLCLVLACFMGSGRMHAPLQSHEGDNIPPDPEVDTPERRKEQEAVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7E6</accession>
    <name>A0A6A6P7E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_384782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7E6"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="34620" checksum="3CF45F0979258D71" modified="2020-06-17" version="1">MAAALKIGQRLRGHLGTYTILKSLHKNVWTASDTNVGTVIIKTAPIKRLNNGKAILNMFQGCPYIRPLLGQIEEPPALVLKFLQDNLLKASNTRRLGRPDIKFVAKGVLEALNIFHEAGYVHTDVKPDNILVNHGNGANRFSGVELGDCADAYCVNPNADPFEEGHVIGAAIFRSPEANLQLRWGTATDIWSFGATLISLIWGQDWHIFIPEGYSVDGPDYPTQVLVKQASIFGPFPYFYIDIADEERQRILAIINNYIHENGLRKPFSMAEDPELTVEDRNFIHEIMKMDPRDRPTAKELLEDPWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7G5</accession>
    <name>A0A6A6P7G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">18S rRNA biogenesis protein RCL1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_384358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7G5"/>
    <dbReference type="OrthoDB" id="1911237at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.20:FF:000004">
        <property type="entry name" value="18S rRNA biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016443">
        <property type="entry name" value="RNA3'_term_phos_cyc_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03400">
        <property type="entry name" value="18S_RNA_Rcl1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF1">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="5">
        <location>
            <begin position="12"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="6">
        <location>
            <begin position="225"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="44281" checksum="B434777C5A8DA621" modified="2020-06-17" version="1">MTAPNQPPLRLTGSRHLSTRLVLSTLTGRPILITKIRPHSPSSPGLAPHEVSLLRLLDAITNGSRIELSQSGTTLLYRPGLIVGSGAPGVGAGGGGADGSANKARRVIRHEVGPQVRRGASYFLVPLCVLAPFSKAPVHAVLHGAGVVTGATSRAAGADVSVDTVRTAVLPLFERFGIMVNIELRVVRRACEAVDAAAAERGAGGEVHLLFGHQVRLPKTLHWLNPGRVKRVRGVAYATGVAGANNARTIEAARGVLNPLVPDTYVFSDVSGAPPAAKDARETPGGEAAGQRRPGIGFGISLVAESSTGCIYSADTAAPPDGGVPAEDVGRRAALQLLEVIARGGCVQPLGMPVVMILMAMGSEDVGRVRLGREVVGSEEWVMLAREVRALGGRGWGLRDVDEEGKGDGDVVVSVVGRGVGNVGRKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7I9</accession>
    <name>A0A6A6P7I9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_176813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7I9"/>
    <dbReference type="OrthoDB" id="2687876at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="50"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="282" mass="32132" checksum="1283CC1FBD3AFB7A" modified="2020-06-17" version="1">MEGRPLNMDLFDKLTFPRLNLKDNTLDDNDLARRCPLDNGHACNTPQQDLGALDALPLELLQVLLAQLDLRTLTDFRRVNKRALQVVDSIPGYKAITTHAPNALRGILSIGTGRWITCETLHDKLCTVECETCGDFGGYIYALTCKRVCFLCLSEHEAYLPVPFSLARRKFGINRQVLDTLPHFRSLPAQARASGRRNTIRRPRNDDPFDGQSGNPLRFMAIIQAPTFKRSSQEVEWGAYCVGCQRSSKQRPRHFRRRFTKESFSEHLHECGHIRDGVHQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Q6</accession>
    <name>A0A6A6P7Q6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_337079</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle</location>
            <location evidence="6">COPII-coated vesicle membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the VMA21 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Q6"/>
    <dbReference type="OrthoDB" id="160405at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03058">
        <property type="entry name" value="VMA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019013">
        <property type="entry name" value="Vma21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31792">
        <property type="entry name" value="VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31792:SF3">
        <property type="entry name" value="VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09446">
        <property type="entry name" value="VMA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="2 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Prevents secretion from ER" evidence="6">
        <location>
            <begin position="106"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="109" mass="11584" checksum="7BB2C2F47489C191" modified="2020-06-17" version="1">MASRRINESEKTYLDSAGAASGPSGKSNIAPAVPAAVIYKLLGFTFAMITAPISIYFLSLNSIFGGNSTFAGFTAAISANVILIAYVVVAFKEDQSERLAEEQRQKKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7V3</accession>
    <name>A0A6A6P7V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7V3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="88" mass="9868" checksum="25479429D6B743F0" modified="2020-06-17" version="1">MWYAWWLAALYVGTWAVCSLGLGWAVLLSARVHCGKRSGGVEVVVREQVDRQGRWRKGLTPGTCLYCCTGQDELKKKILLSTALRRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7W4</accession>
    <name>A0A6A6P7W4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_407720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7W4"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024119">
        <property type="entry name" value="TF_DEAF-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237:SF1">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="9">
        <location>
            <begin position="1175"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1220" mass="135820" checksum="C3D6DD3B96D5CF39" modified="2020-06-17" version="1">MQSPLTAAAFNLTSLFYPTGNTPAVCLTQDLPPKEKADVLLLGCGDARSILFTSWADDGQGKPSTLDPRPLDITCCDSEKAIIARNVLLMTCLLDDEAGSGSATIWNIYYHCFVDKQSLNFLDTQAKKLCAMSTSMHEWHMSEYGSILRFCDSNTLAKVRDVWSSYCTPSTDPDERKRYDERLNTAVQTALQIKKERMGKNITLLTGVRSAAPGGVHCLQDLSNLYNDYWAHGITDRDPKARAEAKYPNPMFFAQDTHTLTLHYGADPLLGFHLASAHAPLTQTTSCRSVLPHSSLHEFVDTARSQFSAWMKAFKKRAKRGITLRFIASDALAFCHTLRHRRATGAETSAHLYREQHHFEPLVLDGEDYAIEGAAPLSFNVIDTSNLIDHIGGINLLTATSPLLQDTVTAVLYTESLVKHGQPHKKWIGKLLCGHFPTMSTLFGLFPVEYWTNATTVSNADEIALNSISQSEGADESQDLSRLTWRRPIATYQGNLVTTAIGPLRFEEDDLAVILYRTYLEAFDGENLGTLLCGLNMANLNLRSLPWAHRGSFAAFLGVLKSRIALDWNKMIHALLDLIQRDTNLMIGMNYHQELVAQLHLLGLYAEPIHIEPICNTFDPWTSNGPDLRSWHNIPELVCLTLRIPKFKLELFKTMPRGKAPTPPVQCGIECVQQGWTNFFAVVQMGFGKISTSGTQNSDNFQISIDEDKDGWNGKSPLLVSFYVPSTVLKQQPQSASVFFGLQSTPHNTVTFSQTLPGLKIHETKQGNGKDVFITKHLPNQTAFPVISSSENEPEADENADFTVNLQAEVSKSMDPPQITSFIGRISIMSETVKLLLKEGAQVESTPLSPGMIKVTIGKSRFHATLCFPNPVDAAKLRTRIARKSSYIEVIAAPANHAHGKTLSTFMYPTHLAGQKPVLWNMPRVNLDMLPVLDITRKKEIDWLESHIRITFSLRERQIREKAIDSPLSSDVRVDFKDSVLTLFMFASGLQTEPQRIFALFHPEAGGVHVLIFVSCIRLDAANRTVILDAAFLPLTKKLVTELDPLLQKYKLGNKLAITIVDDAELALWKQVMPVYVERCRNWDHSASCEYAARKQIPLTLEREQTPLCSCGNGKLPANFVSVPDWNRVAKHAVRAAISPSYAVPYVEPIFDADAIRDRTMAAARAGGDVGGGKCASCGETKSKTGRNLLRCSRCHTVQYCSQKCQRTHWKQAHKNMCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8G3</accession>
    <name>A0A6A6P8G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl transferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_186978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8G3"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="399" mass="44883" checksum="94E873AD3621409D" modified="2020-06-17" version="1">MSLHLSNATNWFLQSPPLEFAISHLRNLLIGALRKGPIPEHIAFVMDGNRRFARNHHIETVEGHNLGFEALARILEVCYKSGVRVVTIYAFSIENFKRSKYEVDALMDMAKVKLQQLTQHGDLLHQYGACIRILGQRELIKQDVLEAVNRAVDLTKANKRAVLNVCFPYTSREEITAAIRGTVMEYSTPLSPPSQSEAARAKRTFSESHIARHIRAQQHLGTVAEENGNGANRSRSSSPVPPGTIEDSSADGEEYEGEKKAKQEHRHQQAPSSTSSDPSTASPSTHPTSAPSPPATSSPPQFLDPETITADTISSHLYSPTDPPLDMLVRTSGVERLSDFMLWQCHEHTKVVFLECLWPEFDLWHFLPVLVEWQWERRKADEVEGLRNGRKRLGWGRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8J9</accession>
    <name>A0A6A6P8J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8J9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="62" mass="6775" checksum="D7F6BAA307BA773C" modified="2020-06-17" version="1">MARARQHPFAPLSWIRGGVAGHCIVTTPQEYAVSYHMCTAASCVRTAESTGSFLPRQLRQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8T5</accession>
    <name>A0A6A6P8T5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD-binding Rossmann fold oxidoreductase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_279927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8T5"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000132">
        <property type="entry name" value="NAD-binding Rossmann fold oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000017">
        <property type="entry name" value="Oxidoreductase family NAD-binding Rossmann fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="137"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="39334" checksum="97B69E2123903C42" modified="2020-06-17" version="1">MAPRRLQVAVAGLGRMGKRHATNVLSRTPRAQLVAVFTPDEGEMSWAQQNLAQWGVKLYTDYDEMLKHAGLDAVVVATVTTVHAEQTIKAITADKHVLCEKPLSTSVEISQSVFDAAKAKPHLKVMCGFSRRFDASYRDAWERTDSGGIGRPSVFRSQTCDKLDPTGFFVQYSAFSGGIFVDCNIHDIDLALWFLGEDSVVKSVMAVGITAVQPELQKHKDVDNGVGVVEFYGGKIAYFYSSRMMASGQHDMTEIIGTEGKLTVNANPRDSLVDMWEPNGVRHEIPPHYYGRFEYAFVTEMNEFTDCCLNGTKLPFKLKGAVKAVKIGCALQESLITGTKIHFDETGRRIEQPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P998</accession>
    <name>A0A6A6P998_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_280766</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P998"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="119"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="559" mass="61408" checksum="C3184A9AE56ED9AE" modified="2020-06-17" version="1">MRSGNYVDDNSIYHSENELESNAGAFTSTSNARRQPEDSDDHNSAAESPADQPEEEKKKRDTPDIDYGEGQGEDLEVGPLELEKMQSRKSVRDPNLVTWDSPEDPANPKNWSVNRKWAAAAIVSAFTFISPLSSSAIAPAISTIAQDFDISNRVQSQLTLSIFVVGYAIGPLLLGPLSEVYGRVPVLQLANLFFLCWNIGCSFAQNTAQLIAFRFLSGLGGSAPLAIGGGVLSDCWKSEERGKSLALYSLAPLLGPAVGPIAGGFITQNTSWRWTFHAITITDAIIQLVGLFLLQETYGPKLLKNKADRLRKETGNVNLHTEFESPDRTLIKLLATSFQRPFRMLATQPIIQLLALYMAYIYGLMYLVLTTYPVLWADTYHESMGIGGLNYISLGLGFFFGAQIGGRLNDRIYRKLKKRNNNETRPEYRAPAMVPGAILVPIGLFWYGWSAQANVHWIMPNIGACLFAAGSIFGFQCIMSYLVDAYTRYAASAIGSATVLRSLCGFGFPLFAPYMYEALGNGWGNSLLGFISIALGIPGPFVLWKYGQKLREKSKFAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9P0</accession>
    <name>A0A6A6P9P0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9P0"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="28222" checksum="90BE10243AEBD895" modified="2020-06-17" version="1">MAFSDDAENVTERSALVEHRARKESQWAISSLARFVGSGLFSPRTMTYDPIVLLLNAPSKEERDTLTARWRDNKLSELNFIGVVSALLAGCLTSTGSWPTILPNGAKTPWSVRCSWYCGIILALASILCTADQILRLHRLSAHREAMPHIRHLLSNRKRDAEGMIRPRRFQFFTWQLPVLFLTGSVVCMVVGMFVTVWAATSRPNGGPWWNENAWVAITFTIIAVFSALNFFLAQMSLFSPINELEMEGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA51</accession>
    <name>A0A6A6PA51_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_261597</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA51"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="6596" checksum="7289CA268F3B65D6" modified="2020-06-17" version="1" fragment="single">SYPCPLAKQFGCSDFFTTSGHAARHAKKHTGKKDAFCPECGKAFTRKDNMEQHRRTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA76</accession>
    <name>A0A6A6PA76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_134317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA76"/>
    <dbReference type="OrthoDB" id="5417895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="673"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="792"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="864"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="700"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="865"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="904" mass="97299" checksum="42F24C56680783C8" modified="2020-06-17" version="1">MGRKPNQLILEFFERGPKLEDNSNRYQHTCRSCGEKFPKGRIDSLTNHLVKKCPALPMRDRQRAILQFHELPDLPEHAAAVAAANGGASTSQAMELPFAPKQPAMSGLDALAEVSRHHLDYKQRSNAPGAAGRGGKRSSNRSNAQPPPPPFTADDLLVDHDKASGAAEGAEETDRASRLTSDHAASAQFLPQDSLTESPNPQSSQAATTSMVPSPLVMAASAANELQAMMPNDNSNQSLAADADQYLHPQGRTPTGWPNNSDPAIDPALPESSKEPPETTPSKAQNYTRPIAMNPSTTQAQFLAEFVDGQRPTKPKVRGRFTDTRRKEVQEVRKRGACIRCRMLKKSCSGENPCATCKSVESARLWKQPCIRTRIADEIDLYSVGLHVVLAFHTIKAVKNQVKFEYLPGRIEASHFPDTSTFATFIMLKAHKQSGSAIDPALLENSGSMQSAMELEILDLERDDLGAKLEQYMRKLSPSFFAAEPSPFMRATLEHAQNMIENLKDSLLSRALELWVATAIITDPELSWALFSNPSSAPAMAPAILSQAELDSSGKHSTNARAQIAFTGAATDSYKLITAELQSATEKRAHDLSKMVMNDLERRLLQRTQANPFETFLVSIILLACVERMCWLFHKWEEPSSLAAAAAQASSVAPSTYDITQSAQLAAALVSSSNGDLDDSSGRNGQLQSDGSDVKLPSAPHQQASSDSPETSFQQTTTGSSLRDNNNGPPPIPLPYRVSAAKWPFDKPPRYFSQQGERFSDVVHMLLRMRNIPPKMARRYDDGALIVAPDNISANNGTGAGPNSGATGDTAGGANGNASAAAIEGDAAARAYFDAVQISADALLQGRLITVSEAQQDAWMDPGLNGNGGPGSAGSGVPGTGHRTGCREWEGRYIMKILGGGGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA84</accession>
    <name>A0A6A6PA84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-ketoglutarate-dependent sulfonate dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA84"/>
    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="745" mass="82386" checksum="8E4052C9833DF444" modified="2020-06-17" version="1">MTTPKKPESPPSYGEQNVGQEGAGGLPPDLSQRLQNLTLPPGDENDRPTVDQCIAHLKLLETFHVLHDEVGNQEGLFDIGEHGVEQSQDPMVHIRVREKRWAVYVARAVDRFRKWWETCVPTSQRGGQPCGKLRATALRSETADMEMAALRGDPTYQMFTSATLPPLDVLIVWHAYLLNPRCFFEDCLRHGKLDFYAVGLPWYLIDKFIDPFSFEYKPPNESRTNFERNTGLCWDNRQDPMIKKISCPKCRKSVTIPWTQGSGYRTGGHIRSASDFAPGIGYADGDLAKDCSSCGFPISHDMLRVRKFHQDLKALLSDQVPLPGTILDVTGKPTKYHPLFDKREPPIMFASSLARSPLSYDLLHVTNRGGATMEHVKRVFEKGLRNKAYVREAKGVPNYRVYAKEKISIRRMFSRYWYNSSPFALDLTGAVIRQGNFIEKMHNLDWLHSPALSWTMERLVVKYGRFFELMKRYPRQVMVPTLDVDLAWHTHQLSPRAYFKHSEALTGKLIDHDDKIEETKLSDAFAMTSKLYQKRFGEPYSQCTCWYCEAIREMHMSSVDRVLKTSKYSADQAVHTDPHATSDPLRSPHISAHNAVRDPKAKISRSCKEAQLDRFYQKACMRARKEHREEPKRSDYYYGYYWGMPMPYPGYYPYAVDPCVAGGTSVYAADPCFHNSTVGAYGACVSGACGGMASAGGGACSGTAGGCGGGGAACGGGGCGGGGGGCGGGGGGGGGGGGGCGGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAC7</accession>
    <name>A0A6A6PAC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_402795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAC7"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="52214" checksum="648F14073B568029" modified="2020-06-17" version="1">MGKTRRAHRKSRTGCVECKRRRIKCGEEKPQCANCVRHQVPCIYPPLQSPTGVPQSPNAQPSPAGFNSRSQFTGIQSPPPWLLSNSILHDDVPNLSPTLFEMKDLVLLHQWTLSTSLSIIYAPGLDVMLQQVLTQIAFSHAYLMHGALSLAAVHLAYLDRSPRHDLVLDAAQHHNAAIRGFRAEINHITPANADAVFATALLNTFYVFATFGRQRDRHDGPAAGCTPRNHYDGGNGGGSAVADTAASRRARILSTEWITLIRGVGAVLRPAAGAVRTGPLRDLVNMGNWCAIDLDCLDSDEDARLRLLRRIWCPQAAASSTPASANASNPSSPAAAAGAAVETEDTVAAYDEALVFLRRSFAWMRMGLQQQQQQQQQQQQHNPASTTTSSSGHTTICSVPFIWLHLVPAGYLERFRQRQPAALVIFAHFGALMHDLDGFWWSEGWGREIVEAVDDSLGTYWTPWLEWPRRVVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAN8</accession>
    <name>A0A6A6PAN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Restriction endonuclease type II-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_383782</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERCC1/RAD10/SWI10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAN8"/>
    <dbReference type="OrthoDB" id="10262814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070522">
        <property type="term" value="C:ERCC4-ERCC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22325">
        <property type="entry name" value="ERCC1_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000001">
        <property type="entry name" value="DNA excision repair protein ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047260">
        <property type="entry name" value="ERCC1-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004579">
        <property type="entry name" value="ERCC1/RAD10/SWI10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00597">
        <property type="entry name" value="rad10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12749:SF0">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12749">
        <property type="entry name" value="EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03834">
        <property type="entry name" value="Rad10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC1-like central" evidence="8">
        <location>
            <begin position="55"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="251"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="362" mass="39507" checksum="1AB64DB8521D2EEF" modified="2020-06-17" version="1">MAGQRLCLVAGRLGVMGGSRKTRTQELFKMSSSSGPPKVQQPKPQALPSRSGPNSILVAICQKGNPILNSVKSIPWEYSDTPADYVLGATTCALFLSLKYHRLHPEYIYGRIRGLGGKYNLRILLTMVDIPNHEDSLRELSKTSLVNNVTIILCWSAQEAGRYLENFKIYEHAAPTAIRAPQSTAYSDKLVDFVTAPRGINKTDAVGLVSNFGSLRTAINARPEEVALVAGWGEKKVQRWCHAVREPFRPRRAARRGAGDAREEDDEATADGRARRRRQDPRLIETSTQAAAAAERRAQASGVGAGPPEVDWAPGEDEEAAMLEPKKAAPQQPATSSKRKPSSGEDELSEGVMAALAKLRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAW0</accession>
    <name>A0A6A6PAW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_138328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAW0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="170" mass="18552" checksum="60DBE65B4E2209B1" modified="2020-06-17" version="1">MEAYVETHKKEVMVKTGSCFPLFCSTDDRKLVGEIQSESFANAFGPNPLAAVSEEGRERISKRNKVRELSGVWGHPAERLWSVPRARAPPPSGRLPRSVLGSANGGSRAATSNCPTRTCLPSAVVGIPPRRARVFQLPLTHRPSPPTSAWAHFWRADRPVTSCSLSFCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB75</accession>
    <name>A0A6A6PB75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_140262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB75"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="21607" checksum="6ED88376240072AF" modified="2020-06-17" version="1">MAPITSHRFGDASETTGREDGEGLAVWTTRSPRSGPAARASSSRAREMPRSNLTSEADGALARALPPRSLRSACRGAVMQMHGRNTARCGAGGLSRTSRVRTRPTASSRPLREPACGGGGGWAVGWTRPGGAEMGREGLLGWGRAETRAGKGRGLFCGALPPLARGGRASARKRDFWSLVRALSRALALMERGDWSAEVLFFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBI3</accession>
    <name>A0A6A6PBI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBI3"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="723"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="243"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="617"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="932" mass="101090" checksum="D914B744B72A79B3" modified="2020-06-17" version="1">MAPAYKVEELLALRDSVSESAVSFDKFGDEDAIKEHVLRPSVSANGIDLKRDRRKQSSEALRKASPRPPGLQSSANPARSDKKPSPSPSVKRGKAEKLLKEHGSPPGMRVTAGGRVVPTDIPPISSPRYQSGNMAGPNKNRGGYNVPPTGANFAFGLNGSRTSNAYANGTVITDGNNRYFQIYDGKPIALNVPSLIVPPWGPVGMNFDGQSSFPSAISGNAPAPVQPVGGPAPQTPAMDNPAAIRLERARREYKQKEMELRDLERREVIMDLPVEDPRRANVIAEKKCRTVELDNVRKQVKELEKAAYGPGETMRPGNMATTVNNQANIGPQLLPSVHFPSEQARAAFPSHLAPYGTSTMPAMPAFQQAGGNFEPFYYPGMFANEYASAYPKQYGMNGFGAVATPVVQPSANENKSPGSNHSSVDRRRSHAIEIRDPRSKQPVNHVKKSSLNPTSPEYHPSDAPEKRPSEVRNLSFPTDSHQELTVSQRNTIAVMTQKWVSEQYDVDFKKKESDTTLNTSDFFPNNPDEHSATKFTGPKPQAAGRHVYPTVHANGNGGPITPPVQQAQSGYPAHRRTPSDEHAQKGCAASPPTDARVPSWNRDCDPTAGVTTPPNHKKGDQDRSDEKPRTHHRRSSDPDFLEGVRHGLNMEAIAKDGEDLYIEGYIIGLKIRKNGAKLSPDSSPPSLKNVYGLDGGATLKRIMANPFYTGSSCAELQRGSVIDEGSDDRPVENPFGAVGSLPKTPEQHTPPSVKKLAGNQVPGTNVSPIHLHQRSKSSGNKACFRSSPLKDMNITGSSPAEIAQRFEATHANHRSGFDGAAEDLTARANAAGNSPPMATTMNEKKTLVVIPGGGSPVKQLANIQTVPTSPNKKPPSPAKVKLEQIAERVRYGSHHMYKPATPPDEKQKRWRATNWRKRFGDVKEKEGAPGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBV0</accession>
    <name>A0A6A6PBV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_360933</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBV0"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="420" mass="47356" checksum="CFDE164B3AA89BC5" modified="2020-06-17" version="1">MGTSNPDSIPVEAPRHVSLTYNNADSRATALRLVLALRPEWQLWEGPIEFVRFTDGITNTLLKAVKKRPGFSEYDIDRDAVLLRAYGKGTDVLIDRDREARAHALLAARGLAPRLIARFDNGLSYKFIPGTPCSPADFRRPKVWPAIARRLAEWHATVPITTISNIEPNDHLTPGQPVPNIWTTMQRWLGALSLNTEAERNRKTQLEEEFGRLLKEFRDAPGLAGKDYVFAHCDLLSGNVILEPPLTDEERQLLASDASSQTSESSQASGAGEPQIVAFIDYEYCSPAPPAFDIANHFAEYAGLECDYSAVPTRSERREWLRSYLCTFDAMLSRPFCPPDTERDLAMLEAQVDAFRGLPGFYWGIWALIQAMISQIDFDYATYAEQRLGEYWAWRGEADGSRAKQGREMPLRERRWAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC19</accession>
    <name>A0A6A6PC19_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_279073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC19"/>
    <dbReference type="OrthoDB" id="2163411at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF32">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="382"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="58045" checksum="606DA7A4BD6B92FA" modified="2020-06-17" version="1">MAQNCVSLAGSTACPAFNSSSVSISSEVTGLFPFLSFVDDVESFDSRLREYVATDFTQLRYQQLIGCSDIDLTNATELYARYTISTLCNAIVQNSIDDCDLSGNETRPLCADTCAQQAISEQEISSTPELCGDPGPNALRQIRADFTNCALPADSLSGTCIDGVDNEPDDCGYQDNLSGLCLFCSESTANGTDTCCYNANVEDRCEGVTLPTPTSMTPLFPSSTSTAAPSSTSSSESTAAAAAASGGSGLSGNVIAGIVVGVVLGTALIVGILIACIFYRRRRRGSKQGSVLNQPSPSRQGGAPPPMSFDGSRQPQHFEVMPGGRVVGMSALEGSSASDRNGSPMGGLETAYRHSSSDEYDTPDSQRNNFGLVGGPLPKRQGSLSSHGEMNDSSSPHSGSGNEQFSSPEGVASGQSEQLQFFKDYYSQDEIRAGDVVATLWAYQPRANDEFELERGDMLKVVGIWDDGWATGVRVSERADEWDARRNPQRDSGVSNGSRRQDDDNNGGGGQVVDGEIKAFPLVCVCLPQHWRKTIEGDENGPSGGPGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCC3</accession>
    <name>A0A6A6PCC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCC3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="133" mass="14642" checksum="C4AB0B653770567E" modified="2020-06-17" version="1">MPRQELPTSLLWSLIASRSLSVAICLGALCLEIYISAAHNSTNLFVYVAFFLILFGDVRSVIHLVSQERNLPLCLLIVWGLIGIGFLVVAAVTTLLWGFGNTSEDSDRWRREHGDEISLMVGLRAVIGTEIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCY6</accession>
    <name>A0A6A6PCY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AFG1-like ATPase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_314334</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCY6"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF2">
        <property type="entry name" value="AFG1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="123"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="639"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="713"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="656"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="725"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="748" mass="82051" checksum="5FE1971863A4C35D" modified="2020-06-17" version="1">MPPNGSRSGLTITNPLVLYRTLVATKRIAPDHGQHRLAIHLQKLYDRLKDYEPSPSYSERLNQLSHSLSNARHDAANTASSSNAASLGTRGVWRSLLEHKEKRDILALTRVLTSHEAALALDSPRGLLLHGEVGTGKSMLVDLFAGCLPARGKRRVHFNAFMLETYARLERLRRRRSRSGGGIGPGMLPDEMVREEHVLLALARDLVAEAPILFLDEFQLPDRTAAKIVSGLLTAFFHLGGVLIATSNRMPDELAKAAGVEFRPPPSTLSSAVMTRVFGSAGWRRKVVGGEPFAGRGEYAAFLEVLKARCEVWEMDGRRDFRRVEYESSGSGSGQTAREVVGETEQPLGEDAAGTLPKFYSIGIPQLATVAETPASLPPDTLATILPTTPVQWQPITLTVYARQLYLPHVYEGHLLATFASLCAATLGPADYASISRSFHTIILTDVPVLTLSRRNEARRFITMLDALYEARCRLFIVRAEAEPDGIFFPDASTPRQDATGQAPEAGSATAIHAETMSEAYQDIVEPFRPNISSYTASGSSPGDYAHAFPPFLSPDALEDDPPTRMRRAAGEGDQQQRGMAGSLEFGHTAAFTGEDERFAYRRAESRLWEMCGEKWWRRVGPESEGEEKESLGANVGQRWVGWRGGGGAAEEENGDEKADHRAGEADGVHQGAETEDDSEGVFRHGASPFRTAVEPPPKIGWTHVWGTAKWGKRAGAWGKGPEGLVERKREMEREQEKDVLEAKKTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDI3</accession>
    <name>A0A6A6PDI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_2750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDI3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="18717" checksum="C88C089BF54541E0" modified="2020-06-17" version="1">MQRKNMCAKGISKPNTAEQALSSLYTEPERSSQAEGRTKNKKASLSRYWTASMQRLMTRCENMRMLQSIAQPRAISHRPAVVLPLRFQASHRHTQRTQCNRTAVRPYHPAVHAQYPILNTRHPIRPLQPLIRFSYHHRLPGCRCCARRGRNGPRSRRPRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDQ6</accession>
    <name>A0A6A6PDQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rdx family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_332507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDQ6"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417:SF2">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="18514" checksum="BECD1551E198E29F" modified="2020-06-17" version="1">MEHPSESRPSQPVKLPRVEITYCTQCRWMLRAAYFAQELLSTFSTAIGEVALVPSTGGVFTVVLTYTPVVVAGGEADGACAAGEGTAQISAETVLLWDRKAEGGFPETKVLKQRVRDRLEPGRDLGHSDVHGKKKAAVKLEESTGEAKGPAAGAVSAASAGQVRRNPDGSVCEDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PES2</accession>
    <name>A0A6A6PES2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_3440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PES2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="473" mass="51119" checksum="6A26EC9DE7D3B62C" modified="2020-06-17" version="1">MPSQGSSTSSRRPAIDTNLGGLFCCSRCFASDTKCHLPRARLSAVMRSFYQPRLLPPTDDNLNSSPEQSHLHRRCADSPVSSIFPTEMRATNILRQTARLPRAMTGCPNSSESTAGSQPPAVFLSLRGGGRVERHTLSRLKLRLRELFQTTKSRVTGHFRPTGAGKEAKPTRPDGLSTIPMADTGAKTITSQEEPPGSDNPMTQGEMQRPGSHGMPCVPDDHTRTFERHGIEERHGLPVNVPCTPICHRCIDSCPCRRASTIGGPPASSCSVPSHPLGPLFILREQGPLPRGHATQAVQSQGGPSQDPSPYPPELTISDHDYSDNEDGQCACRCCVHASVDVIDTASSIQIAPVQPFRAGLVNGIHVPRNDSRQSLASGSSAASVDTAARIPRDPSSHIQAIRNPPSRVLHHWALIDGAWATEPRQLENVPNHQPMAGMRPPPPDDQAPDLGSHNTSQSSRPRSATDSTRQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFH7</accession>
    <name>A0A6A6PFH7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFH7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="280" mass="32323" checksum="E5F7BE9981B3A448" modified="2020-06-17" version="1">MNGAFANIVCAHDAAAPQKNPKSAKFSRGNKRLIEQSTVSAPLRRSKRLRTPPKPPPPPTMPKKRALSDRLSPKREPDPERAIKRRRTPLSVGPPSSVLAKRASVEVEPDEDFVERPRKRSKTPSTIEQPPKVRAKRLRDEEHSEGKCRGEKRMREESTSDNSNGLDPIVESVETVDISAEVERRLREKHEQRRKKNMLVRKRDLDAFQEDAEYESDETWNREYLTGGSRRKRSKRDEEEDRTTERPPKRPHYMLDSEIDDDGDCTTPRKRKMVDKGEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKX4</accession>
    <name>A0A6A6NKX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_359626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKX4"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361:SF433">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="40"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="287" mass="32873" checksum="C3F4C216702F15B7" modified="2020-06-17" version="1">MQAVLQFHQVFQLLMAADKKLPTVDDEGRTVHYYYRYFPLGVKQVLASGTSAWIGQVDDSTVFKYPLVPGGDMTRLDVERKLLEIIGPHERIIGLKGFSDTGIYLERAINGTVAKYILESGKPPPSLKQRLVWCREAAEAVAWVHSRRILHCDIQPTNLLLDEELHIKLSDLQGKQLSENGEVLLDGWSGEPCRFYCPRDDPFDADVKTDLFALGCTIYFIMMGHAVFPDIIDGEDRWYERVGDRFASRQFPQDQHACSAITSKCWQKEYESAKEVVRDIETLEREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL33</accession>
    <name>A0A6A6NL33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 15">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_172255</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 15"/>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL33"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031502">
        <property type="term" value="C:dolichyl-phosphate-mannose-protein mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23283">
        <property type="entry name" value="beta-trefoil_MIR_PMT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000034">
        <property type="entry name" value="Dolichyl-phosphate-mannose-protein mannosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="584"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="613"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="237"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="313"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="382"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="678"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="786"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="678"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="806"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="840"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2452440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="866" mass="96225" checksum="A4B8A4894EACAECC" modified="2020-06-17" version="1">MDVHPPLAKLLITLAGWLAGFNGNFDFKEIGKDYLEPGVPYVAMRLLPAICGILLVPTAFLTLKAIGCKSATAALGAALIIFENGLLTQARLILLDSPLVVFTAMTALAWTNFMNQHEQGPSKAFQPAWWFWLAATGLCLGATVSVKWVGLFTIAWVGALTVLQLWVLLGDAKTVTPRLWFKHFFARLFCLIVIPLTFYMAMFAIHFVCLVNPGEGDGFMSSEFQATLNSKGMQDVPADVAFGSRVSLRHHNTQGGYLHSHPHMYPGGSKQQQITLYPHKDDNNVWLLENQTQPELPDGSKIEGPKAWDELDPTMIEDGAIIRLYHATTHRRLHSHDVRPPITEADWQNEVSAYGYEGFEGDANDLFRVEIVKHLSDGDEAKKRVRTIQTKFRLVHLMTGCALFSHKVKLPDWGYEQQEVTCARGGTLPNSVWFIETNAHPHLPDTAEKVNYRRPGFLAKFWELQKVMWRTNAGLVESHAWDSRPPSWPVLKRGINFWGKDHRQIYLIGNPVVWWASTAAVVLYALFKAVAVLRWQRGYADYERSVVFKRFDYDVGALALGWALHYFPFFLMQRQLFLHHYFPALYFAVLGLCVTLDYATARIAALGLRSRPALGWAILGGFLVLSVVAFWAYAPLAYGNPWTQKECRRAKLLGKWDWDCNAFYKSYDQYSSVASPPVASATPASSPAPAVQQPAGGNRQAQQQQQQQQPLAAQQPPQQKQEEVTPQAPPEAAAASQLLSRDERVEFRDEAGNVLDEAAVAALQGKVSFRTRYETRTRLLDGEGNVVREEVREAGEAGEAGGAAQGERDGRVREGEAPPHPDVMGGEPETVGREPGGAPGEEKRTVGEAEGEKGPRPGSEGREATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLB1</accession>
    <name>A0A6A6NLB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLB1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="24633" checksum="0921F718E444F243" modified="2020-06-17" version="1">MGIKGSRRRRRPRDLSAGSKKADETSRLECASCSTSFLKTIPRSSFPEYYFHLSLGFTTGGGELEGTSKRRGGDERRGALFIVRPRSGCAAGLSDRAIRQSSASQSSASSTSSASSAHLAEHAQNQQPVVDPSPPSSIGPVPSSPQPARRSASPNRRDRKKEPKSCQKPVDLRSVPGELQAPTPQVWGETERETGLRHQGKAEDSGMRRTTVTFRVAATSCRSRVLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLH8</accession>
    <name>A0A6A6NLH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_358941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLH8"/>
    <dbReference type="OrthoDB" id="2096480at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF8">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21274">
        <property type="entry name" value="Rng_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="11"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="606" mass="66723" checksum="AB6DF37A5B698068" modified="2020-06-17" version="1">MPPADAPKTWPVIIVGGGPVGLCASIYLSQLGISHLLFERYPGTSIHPKACGLNQRSTEIFRELGVERAVLEARAPPETCGQTAWFTSLGPQGREIYRRDAWGGWSLSGEYGSASPSPYIILPQIRLEPVLQRRALELNADGIHYRSEVVDVREIGDKATVTVQHRRGGQEAETQEYDARFVIGADGGRGLTDKLGIAWLGERDIVDMVTAHIRSPISQHHDPKPFITWLINPALGGTIGTGYLYHLGPYPSRPETEEWVFAAGMRPDDPAAFDTDAMVRRVHRSLAIPDLPVELLSTSHWRVNAVVAERYRSKGGRVFLAGDAAHRIPPWGALGLNSGLQDVQNLIWKLGLVIKAGEGNEAKYDRLLDTYDEERRPIGERVARTSLHNLQSHTLVMDNALGVSASKSVEENEDAMKTYFDPARKGHKEVGEAVKEAQRSLDGEFHAIGAEVGWFYPSADIDGEGKDNRHGGSLLENGELDTNNYFPSTIPGHHVPHAWLQKGDTRLSTRDLSRAGRFALLTRTPGIWEGVQSEMVDVHVIGGETGWKDEDGTWEKMCGVGPKGAVLVRPDRIVGWRAINTDEKTVGDFGAVMERILRLDKPGPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLI1</accession>
    <name>A0A6A6NLI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_294392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLI1"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF36">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="53"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="445" mass="49247" checksum="0D07D333C4BF20D8" modified="2020-06-17" version="1">MSAFAHVVVRTGRTAFRLQPTVNPLQTALGPSGTRRVLGAVRTYAAAVFQRDKPHVNIGTIGHVDHGKTTLTAAITKRQAEKGFGNYLEYAKIDKAPEERKRGITISTAHIEYETENRHYSHVDCPGHADYIKNMITGAASMDGAIIVVAATDGQMPQTREHLLLARQVGVKKLVVFVNKVDTIEDKEMLELVEMEMRELLNSYGFEGDETPVVLGSALCALENKQPDVGTEKIDELLNAIDTWIPTPSRELDKPFLMSVEEIFAIAGRGTVVSGRVERGVLKRDAEVEILGKQSTPIKTKVTDIETFKKSCEESRAGDNSGLLLRGIKRSDVRRGMVVAKPGTTRVHKKFLTSLYVLTKEEGGRHTPFHENYRPQLYLRTADEPCTLTWPEGTEDADGKVVMPGDNVEMVCETFHPTVLEEGLRFNVREGGRTVATGLVTRILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM16</accession>
    <name>A0A6A6NM16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_358482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM16"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF60">
        <property type="entry name" value="FAMILY ZINC TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04010)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="500" mass="52453" checksum="69665C8BA7657FC2" modified="2020-06-17" version="1">MAAGPDAPGHSPTPDFGYSWAEIPTALLRQELLRRQSEHDGRPPCGSGSNRAAYNTPLHVFALVLILVLSTLACSFPIIVRRFPRLPVPHQVLFLSRHFGTGVLIATAFVHLLPTAFVSLTDQCLPPFWNEGYPAMPGLIAMLAVLIVVGIEMFFATRGAGHIHGSEYDTLVVTPGAGAGEDGHITNGRPRASSFRSDTFKRFRQAPIGGDPDEQAAAGSGIPSIALNSLPGSSENLVAGASPLLSMEAGSSRSGRGGLGSSTELGAEDAAELADRNSDSDLDSDLESDLELSELAPSRKARPRALDLAHGSHRHRPVPKAPATPGTASQQPLTAAQQRKMLLQCLLLEAGILFHSVFIGMALSVSTGTPFIILLVAISFHQTFEGLALGSRIAALSFPAASPRPWLMALAYGTTTPVGQAIGLGIHNLYDPASQTGLLTVGVMNAISSGLLLFAGLVELLAEDFLSDASYESLRGRRRIEACASVVAGAGLMALVGAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMC1</accession>
    <name>A0A6A6NMC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_375584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMC1"/>
    <dbReference type="OrthoDB" id="5407351at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="579"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="637" mass="70957" checksum="3618EBAF94901C8C" modified="2020-06-17" version="1">MGDAACGPSNPLQNFQKHASADRSLQQDRLFSSSRQAPSQSFRSGPGPNAGLLDPEFEAFQAGASHDPVGSQLQHAPPGWPHDLTASWHPQPFQTAPPAQPQPQHPHLEGWAADFHRMHISSPSTAAPAAHAPTQSPWHQDFLQQSRQLPQQQQRRATPTHMHQGSGFYNAMYNASPRHAFAEPSSASALGKQRAADMEPTLDEEAFARAFDAAAADMDAVAAAGVVDERRVDAATEATPSFVTLDSLLQKFEERRTELEEQIDKLNTQSPRDTTLIRRLERHALMVKMDKNDVLALHCEALDVAQEKYELRKGGLERHGAIDRSDEEMQYWHRVCMHLLDRQEMQHRDVLDSRANDAVERTASTEQPAALHLGSMEMKRNLMRITDQYSMLIDTLQSAEILPELPEQAQMTTGQNHMHVPSQFVEYMRELGPIEYVGDHYPQQSKLHTAMEAADLRNQRQDHTEEPLQQERLEALQQEPPQQEEQLHQEQEEQRQQQQPDDGNELAHTAGQLLDSVADNTSQKFRDSNFLALMRRLRDREVRVEGDKMVETGGTSTPAEVGPSLPLFENVGRGGSINASNPGAAPSTSPSSSELSERPPVRHLHSPPVAELITCKVFGCDAAVWDEMHGVGGVMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMC2</accession>
    <name>A0A6A6NMC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMC2"/>
    <dbReference type="OrthoDB" id="5384020at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="275" mass="28323" checksum="0DD1041C1E08629E" modified="2020-06-17" version="1">MSERNSPPLPSPGVQERRRASITGATFVELFGARQSISSTNAPPQQQQHQQGTQAYQGPITSAAAQANRRRLSLTTIGLSGSPNQSSPFGTMRSRTGSISSASVDESPFEDSDGPPAPANNTPATPFGRRLSFGARALRDVRAAGNNSGGAAGGGGGGNSASPNGNGRAHLSNSSSSKQAHQATPTAHGRGGFDFSENLRTRAERQSMSSASHPRVSPPAGASPSGGGGGGMSNHHARAKSVAIMEPPPVTREAPKVKAPDAFQERILKGDFYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMK9</accession>
    <name>A0A6A6NMK9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_293892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMK9"/>
    <dbReference type="OrthoDB" id="4220319at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42090:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="144" mass="15386" checksum="EB19CADF596683ED" modified="2020-06-17" version="1">MATQTTHQPRLRLTCPPRTRIPPTSRRALHRPTSALYARKNAQDREEMDTTSTEYSQSGGNDDAAAREKAAFDPKKSGTSPEEEEEMSREESGGDESSNPLNVSPANQEINQPRNTTEGGAQGSPRSKMSGGGSAPKAGGKKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NML1</accession>
    <name>A0A6A6NML1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_311955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NML1"/>
    <dbReference type="OrthoDB" id="2898618at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF18">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G12480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="32619" checksum="4E34A58619FA0AAD" modified="2020-06-17" version="1">MDFTQNISDAKLFSAKDLVVVLTGGGSGIGAAFASALAQSSARKVYILGRRLPSLQATASTINALPGLAGPDPVVVPVQCDVTDRESAAAAAQRVHDDAGGYADVLINNAGVTGPKHTAVYGAQSLADVQVILQSNADGWPATFATNTAAVVGVAAAFLPLLDAANRRRGWEPGKLEPGAKPRGRGLPRAEGVEDADVRTSQIITVASIAAFNRYVTAGLAYSSSKAGAVHIGKTLATMLAPWGIRSNVLCPGIFPSQMTEGAPTEFPADKIPSGRQGSFEDLAAYLLYLVGKGGSYVNGSVQLVDGGRLSMHPATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMU8</accession>
    <name>A0A6A6NMU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde/histidinol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_358363</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMU8"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42986">
        <property type="entry name" value="BENZALDEHYDE DEHYDROGENASE YFMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42986:SF1">
        <property type="entry name" value="BENZALDEHYDE DEHYDROGENASE YFMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="29"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="508" mass="53615" checksum="B914A9A24FE4C36E" modified="2020-06-17" version="1">MAMPNGTATQASPTSLSDEQLLFIDGEYTKSSKGSTFPVKNPMTGEQLYQSAAAGKADYEIAIQNAHEAFKSWSSTPPSARRLIFLKAADILESYLKQDAPEILSAEVSAVPSWVKVNVLATAGILRETAGLVTHIKGEIVPADRPGTTIMVLREAVGVVFAMSPWNAPVNLTARAIATPLICGNTVILKPSEFSPKSQHLVVRALRVAGLPKGCLNFLPTSPADAPATTEFAIKHPLVRRVNFTGSSRVGRIIAGHAASVLKQCVLELGGKAPALVLRDATIPDAVDAIVFGALSNSGQICMSTERVIVDQAIKDEFISYLLERVAKVRYGNLLDPAMADVSMSGLFCAASTERVIELCRDAISQGAKLLAGDLEARGPQGTILSPIVLDGVTRDMAVFRDETFGPVMCLCAADGDDHAVAVANDSEYSLCASVFSADVMRALAVARRVRAGSCHVNGPTVYIEATLPNGGTGGASGYGRFGGIAGVEEFTERKIVSLAEPGMTYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN84</accession>
    <name>A0A6A6NN84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="16">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_293484</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="16"/>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000090">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000172">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF174">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="521"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1328"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1361"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1393"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1435"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="206"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="19">
        <location>
            <begin position="1214"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="82"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="652"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="857"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="934"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1569"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="866"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="939"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1569"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="13">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="754"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="802"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="825"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2453146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1608" mass="180618" checksum="D5EE984CC27AEC27" modified="2020-06-17" version="1">MGITPAGTSRRPGSPSLTIDTSGNTALPPSGATAPGPGADSTSRSPAGRSTATSPTSPSGFQPLSPRKRHRGYSLRRAVFHRNLEDNSPGANSPSSTIELSDVGHPSSTTVSETSVTAGPAPLELLEESKRAQKSGGIQGISALPHYESWIANRAGKNAGVRGIKALCQQIRKKVLRISDIPPSKDGRHIDLDASRNESLIDERTGRIYIGNTIRSTRYTAWNFLPRQLVAQFSKLANFYFLCVSILQMIPGLSTTGRYTTILPLLFFVSISMSKEGYDDFRRYKLDKVENNRDTKVLHAYRPIPGTTSTEEEDDPKSKKASGHIHWATIKWKDVQVGEIVKLNRDEAAPADMVLLYSSGFNGVAYFETMALDGETNLKTKQTTHSLAKVCKSPGDVAKCRAHFVVEDPNLDLYNFEGKVTVDGETAPLTNTEVIYRGSVLRNTPEAIGMVIYSGEECKIRMNANKNPRIKAPRLQSMVNKIVLVMVVFVILLSVFNSVAYQFWSSRVEDDAWYLTDASVAFFPIFASFIIMFNTLIPLSLYVSLEIVKLFQMFFLNDIDMYHEESDTPFEARTSTINEELGQVSYIFSDKTGTLTDNSMKFRKMSVAGTAWLHDKDIKEVAQEKKTVERKKSKGKRPMRKAWTSVAIEPNRLGRSERGPISPIEDPPFSPLTDAERRPADVKRWSSWTSSARPSKSQPEMRTEDLLRYLQLKPYTLFARKARLFLLSIALCHTCLPETKDDGEISFQASSPDELALVQAARDLGYLVFDRDAQILTLKVYPNGLNAEPVIEQYEILDVIEFSSQRKRMSVVLRFPDKRICVLCKGADTVIMQRLKLATLANQKVVEIEQRANKRKSLEAQHAIARRSEQVERKSSLHRASMSLARSSIGTLGRPSMPGNQMQRTRDELDSWLTQREQDVDISSVENDTVYYSPRPSMQLGSNRQSAAFSDPRNSVQVEDVDELVDESLVVDEPAVIERTFQHINDFATEGLRTLLYGYRFMDEAEYNRWKKIYHDATTSLVDRTRRVEEAGELIEVELDLGGATAIEDKLQKGVPHAIDKLRRANIKMWMLTGDKRETAINIGHSCRLIKDYSYVTVLDHEAGEVEQHIAAAILAINHGQVAHSVVVIDGRTLGLIEADKNLHPLFFELAVMADAVVCCRASPSQKAGLVKAVRKKVKKSVTLAIGDGANDIAMIQEAHVGIGITGKEGLQAARTSDYSFAQFRFLAKLLLVHGRWNYVRTCKYTVGTFWKEMLFYLTQAMYQRWNGHTGTSLYEEWSLTMFNTLFTSLPVIFLGIAEKELRSSTLLAVPELYHKGQRSEAFNFPVYLGWMFMASSEAAIIYFSMLGIFGQALFTHGVDLYAMGVMTYASCVILISIKLLGIEMHNKSVVPFIGMFLSIGAFFLWHLVISAIYAPDNPIYNVRDGFLDRFGRNPLWWITLVLILTSCVLYEIGVQSLRATFWPDDTHIFQQLEHDPVMRARFERAAAPELQQGCASADWQRKEERRAKRAAKKANKKAAKMATAVSLTEEERCEGLKDAGMLSYKEEREREEQRREGEVLELIQSRLEQEREVEREDGSAQKRESGLDVSEMLSRRFGSVRRESDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNH6</accession>
    <name>A0A6A6NNH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_367101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNH6"/>
    <dbReference type="OrthoDB" id="4538483at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="706" mass="74209" checksum="DAC49DC7A7848A62" modified="2020-06-17" version="1">MASQLAPAGSAGSNRAIDAVLSHLDAVIAEPSRILDDKVLSDARLASPSEDQLVELLRKLAALAPALRQNPAPLIELLTGYLDRVRFHQEDADRSTASNGVSNGVSNGVSNGSTHPLYTLDAVLSVFPLDQLADGLTPSASSARPNPFHNLAIAALFLASSKSDLTRLSPAQPAVLRALVLLWLCVEDTGIATKAEAALTHLLKRDKATIIPAGTGVVDEDVPPATDVPVWRRIFGDRDVYGLFFRVCGSGVGGRREERIEVGGGGEEMIVLTMRRSTVAQGRLMEFVLKIARMDWAAVGRSHHPGIESAYMDEAVEVVRGADMEKARRPPVFLDWPAQAMVDKDDIVMYQCLVDFHKGLMALHDNGTEGSLETAARRASAPPHEDLRLLASLPRALLLDTGPTGDDKPLVVEILRSRAAMHDAGVISALAEILHGPRQKHINIEASTPTTSSQAATAPTAATPPSGRGLLEAVCARLAYAAVLRARPSFWDDVIQAANTLAMRDVALAATALIGAMLAGTWAAPGPPQTTPSDPPSASLAAKLSAPERELFNLAFRSAAPDDVDAMDVDAAAPSFDALALAAHAAAVPPRAPALLLARLHPARAALLPFLLAAPPGSAAGGARDEQAAVYAVACARMDVVGGARGAVEAVVARGGDWVDGEDAGWLVEVLGRREAAGLWRGVSEVEMEVRGMGEGRAPVVETVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNS1</accession>
    <name>A0A6A6NNS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_145168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNS1"/>
    <dbReference type="OrthoDB" id="3250044at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="21554" checksum="576832A58EEECDE5" modified="2020-06-17" version="1">MAIRWDTATEDEIIRHCLRSNPDRDVVSELDGGLSVVRISEDAVVKCGLDVSQFEAANQQRAYDILNPAFMRVPRVYRFFTSGLDGYLVMEYINGQPVSSMTDPDAYLEPMAKALKLFECVQRARPGPFHESVAFGRLWLDYDLIAPATVSAIEEYYNKRQLKKSTPQPSRLPAGPIPSRHRSSKYPRLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNW9</accession>
    <name>A0A6A6NNW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH:ubiquinone oxidoreductase 20.1kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_355998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNW9"/>
    <dbReference type="OrthoDB" id="2014058at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008699">
        <property type="entry name" value="NDUFB8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05821">
        <property type="entry name" value="NDUF_B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="17789" checksum="37A2EC603A95BFD4" modified="2020-06-17" version="1">MLSRRIAAVQPLGRAVRPAAAVHRPFSTAQPRRQQLTEAEDPDMNGAYPNPPPVKRQHRDPYAPWWDQQERRNFGEPVHEDNDVLGILSTEDYQHFSQRRGLMLWGFTIATFAALMATVKMLYPDKPAAPRTFPGGLDEELGGQGALRARKEGEDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP79</accession>
    <name>A0A6A6NP79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_120491</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP79"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="640" mass="71109" checksum="6FF2C682E564A9E4" modified="2020-06-17" version="1">MSLPTLLSPRDPPPASIPQAQSAEAGPQPSLSRGSHSADELPRATEGDVTVSESNSSPKTVENTARGARRRLRCSICKQSFSRLEHLTRHERSHRNERPFSCNYCDARFTRKDLIKTHNKRHHKDVMQPWQRDNPAHPGETSSISILDHRSAPPDDSSSRRDGATEGYGNVHHNPGHVSDWNSAFPSSNNIPPAEPVIQQNLYNDWNMSSLMEPCHSAIDFDGFLAEMESSHLSHGPQGNAPNPMAPEHSKSLPSCLAFEGYLTTFFDLVLPNIPFIHTTTWQAEQAHPSLLLAMAALGAALCGKDDISLSLHRVARLSVLNHIKSYNFGSKDQPTWVIQSLFLSMSFGTWSGNLALAQQALACQSILAQLVGYVKNPDDSWAKHKDDPDLSWEEWVSTETIIRTKLVVYVFFGNLNVACNVPPALLNSEVNISLPSSECEWLAPTPEAWIQKRKYPEGRSTSFSDALESHMSHNEDRVVKCSAFGSLVMLHAILQQIWHIRQHNPTRNSPEQILSFELALGKWKIAFENNPESSLSAANPHFWLALSSHVLLASAYTRVYTIIGRIRLSTIIHDADVVAGVMRTSIKEIPRSPGSVNAALHAVYALFLPIRLGRIWTNQSDSGACSLHPYTFCSMQLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPW5</accession>
    <name>A0A6A6NPW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongation factor 1-alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ERF-3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">ERF2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic peptide chain release factor GTP-binding subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Polypeptide release factor 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Translation release factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_374618</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPW5"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018444">
        <property type="term" value="C:translation release factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000017">
        <property type="entry name" value="Eukaryotic peptide chain release factor GTP-binding subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000503">
        <property type="entry name" value="Peptide chain release factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000061">
        <property type="entry name" value="Translation release factor eRF3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003285">
        <property type="entry name" value="Sup35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01343">
        <property type="entry name" value="YEASTERF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Tr-type G" evidence="16">
        <location>
            <begin position="355"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="74"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2453835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="790" mass="84608" checksum="0DC2C41304E8DC7D" modified="2020-06-17" version="1">MADLNSWEDDKDAQDDSLAQQTQQSLNFSPQAGGPNPAASAFRPGASSFQPGAQSFQPQQFQQYGGYGQFQQYGGYGQQGGYGYQQYGGGGGQGGYPQYGGQGGFPQYGQQYGGYGQQQYGGYGQQQQRGGGRQQGQGQGQQQQRQVPVIAKRPSEGGDSTPASEKSAAPSGKSTPASGMSTPKSADAKPAPQQQQQQQQQQKAKVLSIGGDSSAKVDTAGKTKVLTLGGDSPKQDPKASGDQSTASVSTSGKTKVLSIGSTGPSPAPSAAKENADKDVPEAGSKVAAAKAIEKTGEPTPGSSGKASGKTSPTPSSGRSSPSRAEQRAMAREADAVAKAQEQDVDEDTLAEMYGKEHVNVIFLGHVDAGKSTLGGSILYATGMVDERTMEKYKKEAKDAGRETWYLSWALDLTKEERSKGKTVEVGRGFFETEKRRYTILDAPGHKTFVPNMIGGASQADMGVLVISARKGEYETGFEKGGQTREHAVLAKTQGVNKLVVVVNKMDDPTVEWSEDRYNECISKLTGFLKSIGYNPKTDIIFMPISAQTTLGIKDRIPDSVCPWYSGPSLLEYLDSMQTLERKVNAPFMMPIAAKYRDMGTMIEGKVESGVIKKGNTYLMMPNRESITITTLYGETEDEIPHATCGDQVRVRIRGCEEEDIMPGFVLCSPKRPVHCVSSFEAQIVLLELKSILSAGFNCVLHVHSATEEVTFAALLHKLEKGTGRKSKRPPGFATKGMSIIARLEVIGGAGSVCVERFEDYPQLGRFTLRDQGQTIAIGKITKLIKDPNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPZ6</accession>
    <name>A0A6A6NPZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RA-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_292790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPZ6"/>
    <dbReference type="OrthoDB" id="445896at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46829">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46829:SF1">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="63"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="4">
        <location>
            <begin position="367"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="52750" checksum="406BEE8669CF77D4" modified="2020-06-17" version="1">MPADYHSHHPHHHQQHHHHLPHHHRGSSPTDSSGLSPEHTPTTFAHDHGSVDLGSPRGLITQWSAEQCADFVSNCGLEQYADAFIEEGVNGEALIELQHAELKEMGIGSVGHRLTVLKSVYEVKVKQNIPIGPDHYVPLSADPNSQEAPPTQDDIARIIHIIKDRDERILAAEAELRLIKEDFNRVSEENRKLREDILPMIRMAKDRSQPLPTPDDPHHLTSPPNTSQPDQRAGSSLSRKFSTKKLFLGSAPKNPSPTIHHDSTLDPSAAALAASNNLTGALVAAAGAGASQGQQPSSSSASPHAFQHPQPSPTSPAYAQSAPGKTPTAQAARGPPQGAAFDDYHYGGSGSATGTGGSSSNPQVEIFKSFRVSIDDPCHKVLPVALKKYNITADWRQYALYIVHGDQERCLGLNERPLILFKQLDKEGRKPMFMLRKHAAPQEGHVSTVAALPGAGLAQPGAAAGGPAGLAGVGGGAGFGEGGGAGARGGVQLPGGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ77</accession>
    <name>A0A6A6NQ77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_374737</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ77"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="6705" checksum="C571D5BE942E8642" modified="2020-06-17" version="1">MSHESVWYSRPRTYGKGSRSCRVCTHRAGLIRKYGLNICRQCFREKSQDIGFMKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQP7</accession>
    <name>A0A6A6NQP7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQP7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="41681" checksum="7F74EE6C0A4B9A3F" modified="2020-06-17" version="1">MATGSKDYMSSSQLANRRPLSNILEKRRQVSTFSSATPKHESVVAAQGVSKDPPPPKHPVGFNDLPTEILMKIIEYVWAENWDFPSEYLAVHSSSVAASFFFSDGPPSWVFEELRQSKSAKKTPQVLFQINRRIGQIFARMAYQDRVVIVLDHTSWRNIVRLLGDNVMYLRKISLMLYAHADFLRLMGIEVATTGGQGERQRHRVLWRPQQARPFMRIPLREVQFVLPEGELLDTAFGERFSCFRKTAEWILGWFVAHFEGNKDVKVSVGHATRWIFPAEPDVQDKIWVDFKAWIDGLNEMLQRGTLQPVGGSDLGELAREDVENSAGMIVEDATTETVVVNDISLPFVCKCKYKCCWNSKVEPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR84</accession>
    <name>A0A6A6NR84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_381945</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR84"/>
    <dbReference type="OrthoDB" id="1405469at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000306">
        <property type="entry name" value="IKS protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000699">
        <property type="entry name" value="Probable serine/threonine-protein kinase iksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF138">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE IKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="197"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="71"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="127"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="539"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="693"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="862" mass="92758" checksum="AB6AFAE535C0BB10" modified="2020-06-17" version="1">MSLVPYLPAESRQVVLRHGSAVVVYDEDSKQLVLRDDPSLRDASSNDPASSSAAVQLADCPYCHRPLRSRNGHHAAGANGAAAANSHRGLSPRRDGSVSDHAQSQDDGTGGGFVVPMYWRMLHHSTPGMSEDEVDAARAAEDETAVVDDEGTSPAPPSSVPPVPSEAELVGSEPVSPPQPHGIQPSAFSPKYFERFFVEEKELGRGGKGVVLLVRHVLDGVFLGHFACKRVPVGDDHEWLEKVLQEVQLLQGLSHQNLVSYRHVWLEDYKPTAFGPTVPCAFILQQYCNAGDLLHYVLNPSNQVSSTQALKERLRRRSRGQPEPPTALHEPRRMNFEEIFSFFKDITSGLHHLHTNGYIHRDLKPSNCLLHRTGSKIRVLVSDFGEVQATNMTRKSSGTTGTISYCAPEVLRRDSSGAYGNFSLKSDIFSLGMIVYFMCFGCLPYVNSDSLNEENENVDVLRAEITAWAGFQKTERARTDLPEQLYKFLKRLLSLNPAERPATDEILQGIRADPDSDAATASFAPNPNSSIFADIKRRISPADTPDGSPAPSPPVSQPGSMRRKPPGFQLEPRTRFGPSSPPVSATAPGMRSSGLARHPPRSISPTHKAASSAEETDEDDLHGGSSSPTSPGGGVVMRNRARGFLGAGTCLNSTAAGTTSTAAGGRGAALARQDQAYDDASGSVVLRRRNVSRSFSAGPTPPPSGAAHHHHHAHRGSSPLMLPPPRPFARRSRLARWTMVAAARALRAGTALAALRVALFALKLYALLRPCAPFLPRGAVAYPLVVVASLDLVGGVGAALDALLGGGVWEARERGWEWEVLGSAVLVGVHFGVLAMVRRGRGLCEGHGGWEVEVDAEGSMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRE3</accession>
    <name>A0A6A6NRE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_354404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRE3"/>
    <dbReference type="OrthoDB" id="10265903at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_bL36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_bL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_bL36_sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052010">
        <property type="entry name" value="Ribosomal_LSU_bL36"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18804">
        <property type="entry name" value="RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18804:SF16">
        <property type="entry name" value="RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="Ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12308" checksum="974A5C336002A903" modified="2020-06-17" version="1">MLPRTVLLPLRQCLFARSVMPRLQCFSVQHSGFTSMARGMIWTSSAVRRPQVGGTGLKSAVEAARGQIRGMKVRSSVKKLCDGCKSVRRKKGKYVYIICSKNPKHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRF6</accession>
    <name>A0A6A6NRF6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_291474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRF6"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF2">
        <property type="entry name" value="CELLULOSE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025536052" evidence="1">
        <location>
            <begin position="20"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="27"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="26009" checksum="652981890A19FC07" modified="2020-06-17" version="1">MVGLKIVTATGTLAAAVAAQSISYMPFGDSITEIVCWRGYLWEDLQDAGYTDVDFVGSMTTQNPDGCPMSGYDIDNEGHSGYLAIDIANQNQLVQWLQQNPADIITMHLGTNDIVQGHNVQEIIDAFTTLVEQMRDSNPSMKIIVAQIIPLSFNFGSATTESLNQAIPGWAEGMNSTESPIWVVDMADGYTTNDLRDGVHPNDSGDRKMADKWYPFLTHAIDMMSELEEPAAPVPPTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS80</accession>
    <name>A0A6A6NS80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_99254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS80"/>
    <dbReference type="OrthoDB" id="5561659at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16635" checksum="AE9F8A6CE099B4AB" modified="2020-06-17" version="1">MTSARHPLQLPRQPSARDKGHHVHLRRHLSWSAAGIFGPRLLLLACAAGELPAICVDYFRKNPSPLPCFLSHVHSDHLQGPGSLKALFIYCPAATREIPGSCFVIGPFLSPTRVKLASSWSYALVRFLSFSLRTVYTIMLLRLDKYRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS99</accession>
    <name>A0A6A6NS99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 26S proteasome regulatory particle subunit Rpn8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_291363</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS99"/>
    <dbReference type="OrthoDB" id="10256771at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000004">
        <property type="entry name" value="26S proteasome regulatory subunit rpn-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="16"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="39779" checksum="793FB1812FE7C386" modified="2020-06-17" version="1">MPATTAETLSLVTRNVSVAPLVLLSAADHYGRTAKGTRKRVVGVLLGQNDGKNVRVSNSFAVPFEEDEKDPSVWFLDHNYIEGMNDMFKKVNAREKLIGWYHSGPKLRASDLEINELFKRYTPHPLLVIVDVQPKEVGVPTDAYFAVEEIKDDGTTTTKTFVHTPSIIEAEEAEEIGVEHLLRDIRDVAVGTLSTRITSQLQSLQGLHLRLRDIGQYLQKVLDGDLPVNHAILGNLQDVFNLLPNLSTPKTVAGASGTPTMADNSELARAMSIKTNDQLMTIYLSSLIRAITAFHDLIDNKIQNRQQQEERDGKKEETKEDKEKKDEKANGVVNGEAKEGEKGDKSKDKAKEPEKKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSE1</accession>
    <name>A0A6A6NSE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSE1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10156" checksum="19F8CF6271FBCD4C" modified="2020-06-17" version="1">MAAAYSRELVGLVYRCLRPHPRARPTPDQLVKEIGAAMRRVGIEPETFGRGYMQSHPDMFTFGKDRFAIGTVKWQIGKEKPFWGSDDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSF8</accession>
    <name>A0A6A6NSF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobic surface binding protein A-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSF8"/>
    <dbReference type="OrthoDB" id="5400400at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025681929" description="Hydrophobic surface binding protein A-domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="20965" checksum="3F1F85027B752E21" modified="2020-06-17" version="1">MKSIFLSVIALLGIFSAVASSAPGPVPLAKAKTEAIEQRQEADAFAILEDLYSTIQGSTGSINSTAASIGPDTGLIENGTAVVSFNDAISSITSAIDAATDEISVLGAAKRQRGLEARQSIPELANLIFNIIVEINSSLNNIIDLFGLGSIIPSIGPLTMALSRLLSALADVVYEVLELVQQLLNNLLNGLSDALAGLDLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSG6</accession>
    <name>A0A6A6NSG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ClpP/crotonase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_416772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSG6"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24603" checksum="926C62DA85BF3B25" modified="2020-06-17" version="1">MTDEEITLEYRGRIAIITLNRPQTLNALTHDHYFRLARCCTSLPPSPATLTPRAPTQRRRRPRRARPGALARHRPPPLRPQLLGGLAGPNPHTTRAFHAHPTALAAALNGPAGGTRANEALLRSRRVPVGELVGAGCVNGVFDAGGQGESGRFVDLVLREVEERLGPHLNQESVLAIKALIKAPEMDILDRQGVKEVFAGLDRFLKGVPQEEFMKIASGEKKHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT75</accession>
    <name>A0A6A6NT75_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT75"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="62" mass="6867" checksum="854ED74796D28CCE" modified="2020-06-17" version="1">MLLLDPEKPSRPVASGHDGARLHSPPPPRSEPQLDAAKRQEQLCPHACSPYADQRRSARSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTG8</accession>
    <name>A0A6A6NTG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTG8"/>
    <dbReference type="OrthoDB" id="3783539at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="13641" checksum="90CAD529DF918754" modified="2020-06-17" version="1">MFHTDFKNPPLLFFLAGEQSRDKATYSPLSFIPLKPWPRLPSLVRNIFRVSFPTMDNGSIQVLNDSYISQVALVSLLRRLFPNGGYKARYKNNRWVIQAPRHLTDEEIESIWQTSTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU16</accession>
    <name>A0A6A6NU16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_274042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU16"/>
    <dbReference type="OrthoDB" id="3913028at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="142" mass="16349" checksum="744EE0602CE1AB74" modified="2020-06-17" version="1" fragment="single">STSKSSVRYNLDEHDVRKNMLVYSRLPGGSELDIQSQQSLCKSLDSAIDPPLVLSKKKIPRGNSWVEVRQGDLYTDEEREEYSKYPTFMNSLSSISLPRAVYWQRLLLDKFQYLYIVSPRRSPENSPESSQNVSPANSFPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUR3</accession>
    <name>A0A6A6NUR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear pore complex component-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_380547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUR3"/>
    <dbReference type="OrthoDB" id="429932at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030474">
        <property type="term" value="P:spindle pole body duplication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012578">
        <property type="entry name" value="Nucl_pore_cmplx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28003">
        <property type="entry name" value="NUCLEOPORIN POM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28003:SF1">
        <property type="entry name" value="NUCLEOPORIN POM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08058">
        <property type="entry name" value="NPCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="265" mass="28473" checksum="244C4661A91B0C7B" modified="2020-06-17" version="1">MATLASTSTPAKAPATPQSAAVEPPTSTPPTGTWRHPRFDEINRRLNRTNFTDQHVRKIAYNVVLLALTFMVPELAKIALSRGLFETLSSNLTRWWMPLALRLLFVSNVAIALLPLFRRKDDLCDIPLTPTQRKLFGLDPSSAPATPGSNYITPPRYSRSATPRSSGERGGSPRSRRESPLGMSGSYSPASSPLLHRAVGGGFPRRLSYGSGSPLGTSLLGTDSSGGITPPTPTPGPVKTASVGLNNKWLYEKTRSSSGSRGVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUY9</accession>
    <name>A0A6A6NUY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_365305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUY9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025675770" evidence="3">
        <location>
            <begin position="23"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="436" mass="49122" checksum="7D437739EE498589" modified="2020-06-17" version="1">MKSVRQLLMLTLLVLLVGFGQAWFGEQLSPLTSWLLETLDTITTAFVSRLPKFGLELSVAISSVSQYVLSKAKCARVEAAEAKLAIQTASSEALRALMSCLIAAYYTIAGLFHVEYHGIIFATWEAPSTWLMPGAGWSLEACKSGAGHVLQWIQAFLRLRDAFVAYVEELHSSLLAEYYDFLKVVKVGAIAVSAASPIALWIYNSVREDRRDLLTILLQGPIRRAAFRTWQHRNLMNSRQWFVNEYRIDPVASLARLPMVLVSPDIRAAASQTANLIKQAKDKASEIARLRAEITMLECELAKTADENLEHYRRLHHEDWSKLQVDMWATREELSKTQERLRQQEAETARYAREAEDAREACHQATIRMIAVENMLLAAGVRVPATDSESSVASETPKPVGEDEADQPHRNNEPAAQEIPERLRFRWNIPGPYGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVF9</accession>
    <name>A0A6A6NVF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxy-cis,cis-muconate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_289529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVF9"/>
    <dbReference type="OrthoDB" id="1715191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000244">
        <property type="entry name" value="Carboxy-cis,cis-muconate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="40619" checksum="5E9F5E7296122ED4" modified="2020-06-17" version="1">MLHHLMVGTWTPPGAIFSFEFDDEKLTLELIKRTEIPHDEPISWMTFDHAKKNIYGASMKAWTSFSVASPTEITHHSSHPIGGDPLAASKDTNTRAIFVLAAQRPPHCVYGNPFYKHAGYGNVFSVDGTGGLAANVQNFAYADGSGVHGTVFDPAEAFLYSADMYADRVWVHRKEADSGRLAVVGWADAPAPGDHPRWVAMHPSGAFLYVVMEAGNTLAEYVVDGRSRLPVYTRRSFPLVPPAVDLFPAERARRRMYRADVAAVSRSGRYLFATARANAADVTGYVSAFALGPQGQIERQICMNPTPTSGGHSNAVSPADWSDEWLALTDDQDGWLEIYRWRDEFLCRVARCRVQEPGFGMNAIWYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW40</accession>
    <name>A0A6A6NW40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW40"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="17814" checksum="ECE457B05302C9B9" modified="2020-06-17" version="1">MYVCMVTRPRRRAVKEACSGREDASIAFLPPSRGIWFNVRQWEKPGGTDVESYLLGPHTVSQHLVHPEQTQPEPPVAKQNPPINSKPAGGYITAPVMRTSHARAPNKASKRKSEVQNKEVQRTPYSPPLPIPYPQNKQSAGKVARGPQVVVVVVVGPRRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWB1</accession>
    <name>A0A6A6NWB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_67636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWB1"/>
    <dbReference type="OrthoDB" id="268593at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018298">
        <property type="entry name" value="Adrenodoxin_Fe-S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF65">
        <property type="entry name" value="FERREDOXIN-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00814">
        <property type="entry name" value="ADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="96"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="23631" checksum="6BEAADF4BA16CA5D" modified="2020-06-17" version="1">MALQFPVARSALSTSAPRFSAVISVRQTQHLRSYSRTTQRRNCDRWSSSSSRVQCAQRVSWPRWVVSGNLATRRTFSSTSVARHGHLGTPKPGEERKVIFIDKEGERHTFEVADGDNLLDIAQANDLEMEGACGGSCACSTCHVIVEDQDYYDRMEEPSDDENDMLDLAFALTETSRLGCQVKMSKELDGLVVKLPPATRNLQASDFADKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWQ9</accession>
    <name>A0A6A6NWQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeodomain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_288120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWQ9"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050891">
        <property type="term" value="P:multicellular organismal-level water homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901002">
        <property type="term" value="P:positive regulation of response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902584">
        <property type="term" value="P:positive regulation of response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902806">
        <property type="term" value="P:regulation of cell cycle G1/S phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032875">
        <property type="term" value="P:regulation of DNA endoreduplication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000037">
        <property type="term" value="P:regulation of stomatal complex patterning"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033993">
        <property type="term" value="P:response to lipid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000355">
        <property type="entry name" value="Transcription factor MYB124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="53"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="57"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="12803" checksum="1DB6F34BBED2C7F8" modified="2020-06-17" version="1" fragment="single">MPNHRRGPWSQSEDNYLMTIVRHQGAQNWVRVSQILGSRSPKQCRERYHQNLKPTLNHDPITPEEGAKIERLVQEMGKRWAEIARQLHGRSDNAVKNWWNGGQNRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWS3</accession>
    <name>A0A6A6NWS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chalcone-flavanone isomerase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_349215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWS3"/>
    <dbReference type="OrthoDB" id="18193at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47284">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47284:SF3">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16035">
        <property type="entry name" value="Chalcone_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone isomerase" evidence="3">
        <location>
            <begin position="153"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="381" mass="42152" checksum="7E8051EB0AF3DBE9" modified="2020-06-17" version="1">MPQRHWTSWQPPGQRENYIKRQNAIRRMKWSGAGIIFSMAMPVVLIYVYDIPHPDDLKKQQAQEAQRAAASGSNSLVPPSKAESPDDVAATFHGRKVVIAPGGTKIVAQDEQTGAELELVPTGSDRIPHFPRTIHIESSSPAEASRPKNEQDTEYTLLGCGCRTVSFLSIKVYVVGLYVRTSSLQHLQAALIHHINPLASALIPSEKEELRKRLMDPEASARLWDTLLRDPESGLDAAFRIVPTRNTDFQHLRDGWVRGITDRTKQTVDANRKDEYNDDSFGDTMRAFKSLLSGRGKAPQGSVVLLTRDADGTLGVRYQPKEGKGETTELGKIEDDRLARLIWLLYLGGKNVSSEAARGSIVDGVVHLAERPVGTVETMVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX60</accession>
    <name>A0A6A6NX60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_372694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX60"/>
    <dbReference type="OrthoDB" id="2679825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054208">
        <property type="entry name" value="DUF6914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21858">
        <property type="entry name" value="DUF6914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="21528" checksum="A7245BED1F584DC1" modified="2020-06-17" version="1">MTATVAMAGLRASPTPRRALNKKRVYIALYGRGTNKTSSEPYHWAIIVGPKKEVENGQGVRYHARQIFDATRPGKTSWAFERREIALAPTSLLLARVLVAKVADDAQLGRTLGAVAVVQNDQDPAWNCKSWIRTALAALEGDGRSLGTRVTDWRTVEGVASAYVCCKKRQRRFDTPGAFAAGTVPTFDLLAGREIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXK1</accession>
    <name>A0A6A6NXK1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_348380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF24">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="691"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="912"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="964"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1078"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="921"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1083"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1283" mass="144383" checksum="0A9CB45989CDBD08" modified="2020-06-17" version="1">MLERASACLDCAGSRVLLRGGSSKQTIRSRRMLHSAFWHHGACDLEFLPSWWATVQDNSPGDKSADPSTAMADYDQQPLFLNFLYPAKTMALLKTISTYGWEDWERRRQKSRHGLWRRMRQFSSIAGAGPFEGIMVNGGNEHDIGKVERLAAEGGDRAVYEELMSARPGDTRLDYDRIWNLFLSLDRSRTDRAVTIQTMRALALSGRIEDAERAIRLFEMLGTAERNEEAYKAAIIAFVHLSELSKGVEVCKQALENGATIEDAVMLLLVHCAARAQWALAFVVYSSYLRAPRRKDPESHKARQRLEQALCKISPSLKDLGSLVRFTEDQRSHDQRSCEDMNLFNFTRTLMHSVLDKAEELPLRWIQETLSQVDTESPLREFYYHNIIRNLFRIGRETNSSLTTTAYVLYDEFRSGFTLDREKEKSYPSRQILLLVLDNLCQDPGTGVGHATISNVINDHQTLFGALPVPKLLTVMWHYAKLGDAEKVRNCMDDLRASSPRALRNRATHHALLYAYARRGNSQATREALDRMSKDFDTTPSTRSWNILLHAYARADDVKGATDSFREAFLSHAGERPLQPDEYTFGPLLVLHSARGDVESVERLLDLAESKSVPMSTHLIRCLVMAYINAGDVASAIRISEHSVREKKVGRLSGRITPIWNCLLAVSARQRDPNTTMKIYKRMSDLEIRLDAHSYASIMISLTAIHKTDAAFKILRKVMPRDGIRPLGIHYAIVMAGYINQNMPNRAIIIGNSLSKYGVRETLSTRLALLRAKSYDAVIEKDNGEQSTMQELVKQLQAFLDETLATESSTDISIQQPHLGLNKERLVDADPELYVSFITQLVGRTGATDVVQQLLDSFSELQAKKSNDRLHKDAGPGINMISALMVAYNCKGDHEKVDQCWRMVIQRAAALSDPEQDTDRNFTSNIGDNASGDLGSSQAIPAHDKEPDKTGDELLQSQREALPAHSPVYSRESDLSNPPTQTDELRLAKPPPARADILNRPLNIYVRSLAARKRHGTVFATLSTLRAAGYTVDNTVLNILVQLLARSGWPLQAFAQCEKELMRDWRGWNTREVTKQRRSRWYRSHEATEERELDSSSKQIDIDDADPLADFGGNDGSDGIRGTSPRRIASGSRRSTLFKAMSASGQESRPVIPTASLVLPTYKTMIILGAVMRRVRRAEALGRNGREIIRMRWEDDFNTAVRKAGGDAIGGEKDDMSGNGDLVAEDLIGQSGRELFTVEETVGMRRLRKYAPRTVEAVESMPKIDDWQQRKYLFRSDGQLPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZA6</accession>
    <name>A0A6A6NZA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZA6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="11354" checksum="9EEE56A7579C0F89" modified="2020-06-17" version="1">MAAVPAPGAVAFRPFLPKHPGLHPGSHAGTLSVHLSHKMPSPYPYGPLPSPYLREYSTRFIHPRLLHPQAHNPQPRPQASSLSIRAPLPPHLRGAAASAARFKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZG2</accession>
    <name>A0A6A6NZG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cysteine synthase 1</fullName>
            <ecNumber evidence="5">2.5.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">O-acetylserine (thiol)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">O-acetylserine sulfhydrylase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">O-succinylserine sulfhydrylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_286811</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-succinyl-L-serine + hydrogen sulfide = L-cysteine + succinate</text>
            <dbReference type="Rhea" id="RHEA:53816"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:136856"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZG2"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000011">
        <property type="entry name" value="Cysteine synthase (o-acetylserine)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007989">
        <property type="entry name" value="PRK10717.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="19">
        <location>
            <begin position="46"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00072087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00078262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00079147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00081847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2456882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="378" mass="40900" checksum="83A02E5DE91D1D66" modified="2020-06-17" version="1">MFRIGVRRFSSTALRAAEWTAQVEAANARGVAISKAQGIAQRGLIDAIGNTPMIRLKHLSDETGCEVLGKAEFQNPGGSVKDRAALYVVEMAEKAGQLRPGGTVVEGTAGNTGIGLAHVCRSKGYRLVIYMPNTQSQGKIDLLRLLGAEVYPVPAVAFDNPENYNHQARRHAERLDNAVWTNQFDNTANRQAHIETTGPEIWAQTDGKVDAFTCATGTAGTLAGVTRYLKTVSDGRVKSFLADPPGSVLHSYITSGGKLMERTGSSITEGIGQGRITDNLKPDIGLVDGALHISDEKTIEMVYRCLDEEGLYLGASSCLNVVAAKEVAEKLGKGHTVVTMLCDGAYRYAERLFSRKWLEEKKLLGAIPKHLEKYIVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZR0</accession>
    <name>A0A6A6NZR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_35842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZR0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="465" mass="52105" checksum="FFB48BBFE0A98F8A" modified="2020-06-17" version="1">MDSPQAAYFSPGEVKHKSNFKLSHDGDPGTGAIIWTKIKENSVPSAVGGILSAFCIAAIVFGRYRIVALYYQILARIRAALNWPRGLIRNKVLAKSRRRKRMQRWAGDDRDPELGSEDYTMDDLDYADSVEEVQRRGRGEDEAVIMLSLAFLMFFMRTASIAPTSRRRIRQNLYSSSSSSRARYSYNSGPARSDRDRDSGNPGTGTTASLVRSFRYDLLPPTLEQLTRAHTRGQSLPMRMGRSRGISDWNPTTGNQARRPAAPSPSSRNLRDLSSVVLHNSDANPRRKQTPSSPRRNLPGTASTGSRGEETSRAHAVKRKPLTSLSTHPIPDMRAVPEEFIKEFHPARTKSRPPHMKASARKDTRFAHLETPKRTKRATTKKESRFLPDLTRIDSSTALFQLGIRSARVDVAPSSCRSSVSRDLDSRPAVDANIKKKEPADSHTPTKTVEVPLLREKKDKSRCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZS6</accession>
    <name>A0A6A6NZS6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Halotolerance protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_286286</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZS6"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000183">
        <property type="entry name" value="Serine/threonine-protein kinase hal4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="81"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00078109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="366" mass="42187" checksum="72B4DAFB014AAB1A" modified="2020-06-17" version="1">MKRFWMHEDGGHEHHLKSAKRQEKLSYLVQNFVLGRKKGEHGDEQPLSLMANWADQLRNDKDKLASVKEGPSSLTLVQKYGKCQEVIGRGAFGIVRVAHKTDAKDPKREQLFAVKEFRQRPGESDKHYQKRLTSEFCISSSMQHPNVINTLDLLKDDKGDYCEVMEYCAGGDLYTLILAAGKLEVLEADCYFKQLMRGVEYMHEMGVAHRDLKPENLLLTQHGAIKITDFGNGECFRMAWENEAHMTAGLCGSAPYIAPEEYTDQEFDPRAVDVWACGIIYMAMRTGRHLWRVAQKGEDEFFTRYLEDRKEEEGFRPIEVLKRRQCRNVIYSILDPNPVRRLTAHQVMFSEWVKDINVCKAGNEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0E1</accession>
    <name>A0A6A6P0E1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AhpC/TSA family thioredoxin peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_421440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxiredoxin family. Prx6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0E1"/>
    <dbReference type="OrthoDB" id="2996783at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03016">
        <property type="entry name" value="PRX_1cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1020.10:FF:000001">
        <property type="entry name" value="1-Cys peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000011">
        <property type="entry name" value="Peroxiredoxin PRX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1020.10">
        <property type="entry name" value="Antioxidant, Horf6, Chain A, domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045020">
        <property type="entry name" value="PRX_1cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009668">
        <property type="entry name" value="PRK13189.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF9">
        <property type="entry name" value="PEROXIREDOXIN PRX1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 6 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="52"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="7">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="29059" checksum="6CFB75C1F04F0489" modified="2020-06-17" version="1">MASLFYRAAPRALNTGLRAAARPNCSAVRRPAVLTPLLRRSLATPAAEQPRLRLGSTAPNFKAKTTKGDMDFHEYLGDSWGILFSHPADFTPVCTTELGAFSKMADEFAARGVKMVGLSANDLSSHDAWIKDINELSDTNLQFPIIADADRKVAWLYDMIDQQDLDNIDQKGIAFTIRSVFVIDPAKKIRLTMMYPASTGRNAAEVLRVIDSLQTGDKKGVTTPIDWLPGDDVIVPPSVSTEDAKKKFGEVRELKPYLRYTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0S7</accession>
    <name>A0A6A6P0S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_39254</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15480">
        <property type="entry name" value="fMyo2p_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01380">
        <property type="entry name" value="MYSc_Myo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046943">
        <property type="entry name" value="Fungal_Myo2/2A_CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036103">
        <property type="entry name" value="MYSc_Myo5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50084">
        <property type="entry name" value="Myosin S1 fragment, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="12">
        <location>
            <begin position="74"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="11">
        <location>
            <begin position="1233"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="657"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1104"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="917"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1118"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="168"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1545" mass="176404" checksum="E1F96283F3241879" modified="2020-06-17" version="1">MAHIYDVGTRAWQPDPTEGWVASEVEQKLVDGNNVTLIFRLDSGETKEVKTTLDALRDSSNDTLPPLMNPAMLEASDDLTNLSHLNEPAVLQAIKLRYSQKEIYTYSGIVLIATNPFAKVDALYVPGMVQVYAGKQRSSQAPHLFAIAEEAFSDMLRDNRNQTIVVSGESGAGKTVSAKYIMRYFATRESPDQIGKRVKGRVDAMSETEEQILATNPIMEAFGNAKTTRNDNSSRFGKYIEIMFNRQTDIIGAKIRTYLLERSRLVFQPLKERNYHIFYQLIAGATDAERNELGLLPVDQFEYMNQGHAPTIDGVDDKAEFDATRKSLRTIGVSQDTQSEIFRVLAALLHLGNIKITATRTDSSLSPEEPSLVKACQLLGIDAANFAKWTVKKQLITRGEKIMSNLTQQQAVVVRDSVAKYIYSSLFDWLVDIINKSLATEEVLSHAHSFIGVLDIYGFEHFAKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYLREQIDWTFIEFSDNQPCIDLIEAKLGILSLLDEESRLPMGSDEQFVTKLHHNFSGDKHKFYKKPRFGKSAFTVCHYAVDVTYESEGFIEKNRDTVPDEHMEVLKGSSNRFLKEVFDVASTVREKENAAAPTKSGAIATSGRRVGVAVNRKPTLGGIFKSSLIELMNTINSTDVHYIRCIKPNEAKAAWKFEGPMVLSQLRACGVLETVRISCAGYPTRWTYEEFCLRYYMLVHSSQWTPEIRDMANAILRKALGPAKSDGTDKYQLGLTKIFFRAGMLAFLENLRTSRLNDAAVMIQKNLRAKYYRRLYLETRGSLIVFQNAVRGFLSRMRAEEIRQIKAATTIQRVWRGQKERKKYNIIRKSLIAFQASAKGYMLRKRLMDTRLGNAAVLIQRNWRSRRQLKAWRSYRRKVVIIQSLWRGKSARREYKTLREEARDLKQISYKLENKVVELTQSLGAVKRENQALQGQVENYQGQLKSWKNRHNALEARSKELQTEANQAGINAAKLAAIEEDYKKLQHNYEESSANMRRLQEEEKQLRQRLHEATDELQQSKQRNSRIETERLSLRQQLTDLQDQLEIAKRSAPLNGEAGVNGAVNHANQGPIPGLINLVSSKKPKRRSAGPDRIDMDRFSTTYSPRPVSMAVTGTTVHRQNLSGSTFSPGLDNIEFELENLLSDEDGLNEEVTMGLIRNLKIPPPSTSPPPTDKEVLFPAYLINLVTSEMWNNGFVKESERFLANVMQSIQQEVMHQDGEEVINPGAFWLSNVHEMLSFVFLAEDWYEQQKTDNYEYDRLLEIVKHDLESLEFNIYHTWMKVLKKKLHKMIVPAIIESQSLPGFVTNEGNRFLGKLLQSNNQPAYSMDNLLSLLNNVYKAMTAYFLEGSIITQCVTELLRLVGVTAFNDLLMRRNFLSWKRGLQINYNITRIEEWCKSHDMPEGTLQLEHLMQATKLLQLKKATLNDIEIIQDICWMLSPSQIQKLLNQYLVADYEQPINGEIMKAVASRVTEKSDVLLLQAVDMEDSGPYEIAEPRQITALETYTPSCKLPCRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P139</accession>
    <name>A0A6A6P139_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_371989</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0357 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P139"/>
    <dbReference type="OrthoDB" id="447314at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018559">
        <property type="entry name" value="DUF2015"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023:SF1">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09435">
        <property type="entry name" value="DUF2015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="126" mass="14446" checksum="D55D3579328F9858" modified="2020-06-17" version="1">MGRYTLYSIFLVVLVFATALFFTRNRWLPHIPVPNLGYVYQRLPSSFRGDMDAGLSSSAFDLSANVESGDSRQGLDDRGKREVQKIMQSRKVGFDEARRMYTEQRFARNNIGPDGRPRDPKFVSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1B6</accession>
    <name>A0A6A6P1B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_415169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1B6"/>
    <dbReference type="OrthoDB" id="5412996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025359652" description="Aminoglycoside phosphotransferase domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30567" checksum="F8D4E68B8ED0DB98" modified="2020-06-17" version="1">MLSSFLIYLFPLAVYCCKICLAGQHYPGIRVTEASSLITGSCNVCYTVTFEDGFRTRDELLVMGFLALGAGQWGCGPYIATTVVEGTLLSKSFGNPGVHYGVAQVMLELSKPTFRSIGMTKRPLTLNMDELKNYVARCLSLRLTRQIPTETGLFRLFRNNLRPSNALVSGSDLTVTGVIDWGFTYIAPAEFTHTAPWWLLFESPEACESDLNRIFLQRLLDRIALSVENGLFWFCLAARKSFMFDDIYWTILVEKYFSHLSSLDDRLPLNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1C2</accession>
    <name>A0A6A6P1C2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_342816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1C2"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34994" checksum="0C3714A391E4159B" modified="2020-06-17" version="1">MEAIRNTPLGLITVYEGYDPEIDIVAVHGLGARPEWAWTRRVEAPGGKMKEVKWLSDPNLLPARLPRSRVMTFNYESRWHRNAPKHRKTSVADNLLRCLEEQRQNNPRVRNRPLLFIGHSYGGIVIEQLIVHTLHREIGYIRKATAGIVFLGTPHRGTDVQSWGELMAVMGQKMGLGSHNEILKELRADSENLKDMSSAFSRWVNRASVPIVCGVELYETDYGKRLGGILPMKAMVVPEDSACIDGHPRLYLYEDHLKLNKYCGPNDSSYRAVSSQLVDMALTAIPTVRGRFGRTQPTSYRLPPNGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1D1</accession>
    <name>A0A6A6P1D1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_391740</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1D1"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="616"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="343"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="347"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2457628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1037" mass="113517" checksum="7532F0FC7E0C1A9E" modified="2020-06-17" version="1">MSSPASRRTQRASASATPRRSGRGSRAPQSSPAPSRVTADDQLLSEASQVSDRAGPASQSTPRAGGAGGLQPPQTSSPLFFLSSPANGAGPVNGDMSSSPLRSDRDMTPRASRQAIGESSPLRYASSSSVVGGHRGSDAQPSSSSGLFVRSSLHDPPPSALRRRHDLNMDHLLSSGGSRRRRLFIDEHGMTVSGDSAVPGSDAATFSNLNPNTDEAERLAGRDEEEDKRVLWGSTISMAQTLEIFREFLLNFQKKYRMMLEGELEPGEDLPAGHPGLEKENIELLKTMLDLGVTPFNLDLRNLKAYPPTQKLWYQIQAYPEDMIPMMDVAVKDVMLELAEKKMNEMRQQQQQRQQQRNRGARDSSSIPPLPSSDIDSPTAQPAEPPTEIPDFYRDVQDKIYRVRPFGFDETINLRELNPGDMDKLVSIKGLVIRTTPIIPDMKEAFFRCAVCNHTVKVDLDRGKINEPTACPRPVCNSSNSMQIVHNRSGFADKQVIKLQETPDNVPDGQTPHSVSVCAHDELVDVCKAGDRVEITGIFRCDPVRVNPRQRTVKNIFKTFVDALHIQKVDKKRLGVDVTTLEEELANQVVGDTMETRRVTEEEEQKIKETAARPDVYELLARSLAPSIYEMDDVKKGILLQLFGGTNKSFEKGGSPRYRGDINVLLCGDPSTSKSQLLQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVETRQLVLESGALVLSDGGVCCIDEFDKMSESTRSVLHEVMEQQTVSIAKAGIITTLNARTSILASANPIGSKYNPNLPVPQNIDLPPTLLSRFDLVYLVLDRVDEANDRRLARHLVGMYLEDNPDNASRDEILPIDFLTAYVSYARTHVHPRITPAASRALVDAYVAMRALGADVRAQERRITATTRQLESMIRLAEAHAKMRLSPEVTAADVDEAVRLIQSAIKQAATDARTGLIDMGLLTEGVGSGERRRREDLKKAVLEVVEEAAGGAGAAARVAEVTRRVAERGGVQIESSEMAEALRALESEGKVAVSGEGARRSVRRVVGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1D9</accession>
    <name>A0A6A6P1D9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_304463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1D9"/>
    <dbReference type="OrthoDB" id="3486565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="214"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="472" mass="53357" checksum="31BBC0A4C40F8664" modified="2020-06-17" version="1" fragment="single">MSLCGDCRELKFELTTPAKRTWRSKLLYWKATEASGFVRPDRTRLASFEVLEQNSAGGCVFCNIIMWIVRSDPDVHSLIKRTLRDSNDYVKLNIENLAGLDSVDGEHSSEKTYRTGNLLVSTRTTERNLKYAVNRQDQFKSGLATWQTSTNVTFDHSLPVVRQWINGCDSSHPGCPQDSQPLPKRLVHVAFSSGQIVLKLVQQDGLQEAKMGRYAALSHCWGNPEGVLRTLSDNIHIHLESIPFDDLSKTFKDAVRITKELGLCYLWIDSLCIVQDDLHDWQEESAKMPEIYQNAYVTIAATASPGSHRGCLFPRDPANRTNSLDKSPLHQRGWVVQETVLSQRIIHFAEDQLFWSCRSGTKSEDGTYNEPSAAIPADLSFPLAAHISWWTWVENYSARGLTMQSDKLPAMAGLTKLVERERGWQAAVGLWMNDLHYGLLWRTEGAARRICPDTDNVYIPSWSWASIKGPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1K5</accession>
    <name>A0A6A6P1K5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_303797</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1K5"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000050">
        <property type="entry name" value="Nuclear protein (Sgd1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF4">
        <property type="entry name" value="NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="632"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="596"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="865" mass="96733" checksum="7E3E117AC2F484F1" modified="2020-06-17" version="1">MRQRTSRGPKLPRELLDKIEGTSGGRSVGRPASNRKQRRKAEREQKKAHRRRTPGDTGIGVSQDDDELGLSEEQSSESTSPPQRLRPFSTNLQPTKSILKRAPEAEPAEQSHDDDHSVPAKAISRTLKNKLQDDDNEIAALEKRLGIKSKKKLPKSFEDDGLDDILGDTGGYGSDDSVGTKRKRPGDGDWFNAKRRKAQMANGTVENAAGMDDNENDFGGLSSSGSVDEDSILGETEDEENSEDKDETMVDSIEEELGNFSAEIGDDGNEGDCDAFDSEEISTAEPKNQRENPYVPPVPKDAAHTAKYVPPSLRAPSSSEQESLFRLRKQIQGLLNRISEANMVSIVRDIEQLYQNNPRQHVSSCLIDLLMILVCDRTSLNDTFLLLHAGFAVAIYKVVGMDFGAILVERVVADFDKFYGMHNSYGSGKETSNIITFAAELYNFQMIGSKLMFGYIRHFLEELSEVNTELLLRVIRNAGSQLRQDDPTALKDIVSFQQQAIAKIGHSNLSVRTKFMIETLNDLKNNRMKTGQSTSALHQEHATRMKKMLGSLNSRTRATEPLQVSLDDVRDAEKRGKWWLVGASWRNETNDKSFQVNEKEKPTKKMGMEPDEFGSGTTDIMQLAREQRMNTDIRRAIFVAILSGTDYNDAYQRLSKLKLKKAQEQEIPRVLTHCVSEELTYNPYYALIARKLCAERRFKYAFQFTLWDLFKRIGEKGSDEDNEALEDKLGESLGTRKVVNLAKFFGSIISASVLSIAVLKPLKLPYLGSKGKTFVEILMITTILESQKQYANKQDEKALLAAFSQGDLPASASEGLQLFLRKVVAKSDLVGNKADRQTVKWGSKLVANKLEERVFNGGQEIGSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1V9</accession>
    <name>A0A6A6P1V9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">6-phosphogluconate dehydrogenase NADP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_343419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1V9"/>
    <dbReference type="OrthoDB" id="5399569at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050812">
        <property type="entry name" value="Preph/Arog_dehydrog"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363:SF0">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="6044" checksum="CEFB7349826351E6" modified="2020-06-17" version="1">MAGGSVGLIGMGDMGRMYARRISAAGWRVNACDIPEKYGMLKEEFGHNVGDRANLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P350</accession>
    <name>A0A6A6P350_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_412133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P350"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="20653" checksum="D503696E6B3CE304" modified="2020-06-17" version="1">MASSPQQRGSLGPRPMDANQRQSASPWPKIAGPRSRAGPWYIGTVAAPWTDARHGSRGSQQPKAIAALSSALLKACSTPFRLRACPTARGVLFRLHRDRPAPPYGASPSAPPDLDLRCFAPQLVRFRGDRGNRDNRGLMMRDQASHERAAYWPAEGPSGPRHAALGGMTGYITYHHGHLGSSRHHLRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3C8</accession>
    <name>A0A6A6P3C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium:solute symporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_216267</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3C8"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015489">
        <property type="term" value="F:putrescine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1730.10:FF:000006">
        <property type="entry name" value="Urea active transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="606"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="659"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="681" mass="73816" checksum="66346BC5DF7648D5" modified="2020-06-17" version="1">MGICLIYYAHFWKESSVQYREHGLYLQALENFKLTRCRYNYEVQTSEMFTTAGRTVKTGLVASAVVSSWTWAATLLQSSGVAYSYGVSGPFWYASGATVQIILFATLAIELKRRAPNAHTFLEVIRARYGVVTHVVFIVFGLMTNILVTAMLLTGGSAVVTDLTGVPTAAACFLLPIGVVLYTLFGGIKATFLTDYAHTVVILVILFTFAFTAYATSDVLGSPGRVYDLLTEAARQHPVSGNADGSYLTMRSKEGAVFFVINIVGNFGTVFCDNGYYNKAIAASPIHALPGYVIGGLSWFAIPWLCATTMGLSALALESNPVFPSYPNRMDPADVTAGLVLPSAAVGLLGSGGAAATLLLIFMAVTSAMSAELIAVSSIFTYDVYQTYFNPQASGKRLIYMAHSCVVGYAVVLAGFSTGLYYIGISMGYLYLLMGVIISAAVLPAALTLLWSKQNWWAATFSPILGFIFSMTAWLVTAKKKGGELSVATTGANDPMLAGNVTALLSPILFIPVLTYALGPQNYDWQSMKAIRKGDDHDFAKSEHVDLEMIPGERQHSVAEEQAEQAKLKKNATYARALTVFLTIALLVLWPMPLYGTSYIFSKPFFTGWVVVGIIWLFCSSFCVGLFPLWEGRHTMARTAKAVYADLAGRKKPKTIHGQAEAVEETTGQPTPSEKVVEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3F1</accession>
    <name>A0A6A6P3F1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="9">HMG-CoA reductase</shortName>
            <ecNumber evidence="9">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_284485</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="9"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3F1"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.770.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025583">
        <property type="entry name" value="HMG-CoA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13323">
        <property type="entry name" value="HPIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="11">
        <location>
            <begin position="268"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="679"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1177"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="695"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1188"/>
            <end position="1198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1224" mass="130827" checksum="D7EB82A5B1FD9EA9" modified="2020-06-17" version="1">MIGAQFLPSRFRPAAEDGDGNGSGNGSAAPRSWCNRHITPLLQSVSRQACTHPVQTILFVALLASTTYLGLLESNLFESGADDASAASVPLGAADFAALLAGSKSLRAGPETGWKWQIEEDASAPATMATAAHLALLTLVFPDTASAGSARTAPLPHGVPLPRNSSAELLPCSTNPISQMAHDTTLAFSIPFAEAPELLAALHEIPLPPEAAEARVTDEDDDEGRAPYEEKKWIMKAVKGPGSGGLKKWAVNAWTAFVDLLKNAETLDIIIMTLGYLSMHLTFLSLFLSMRRLGSNFWLAATVLFESVFAFLFGLTVTTKLGVPLNMVLLSEGLPFLVVTIGFEKPIVLTKAVLSANLDMRRTTNQQNGESSEKGSKKSHTPLPIQHAIQVAMKERGYEIVRDYAIEILILIAGASSGVQGGLKQFCFLAAWILFFDCVLLFTFYTAILTIKLEINRIKRHVALRKALEDDGVSRVVAENVAASNDWPKLDPSGGSDSGNEGQSVEYGVFGQKIRDSSVPKFKVLMVTGFIVINVLNLCTLPFRGSRSSTAPAMSGLSSVVTQPPMDPFKVAGNGLDEVLKSAQNQQQSTLVTVLTPIKYELEYPSVHYAEPRGSSKSAFETEYGDPLLDGMGGRVVDSILKSLEDPVLSKWIVVALAMSVALNGYLFNAARWSIKEHHPHMQPPTESEVLEGEPPSKNDIPREAEPPKNGTIAPKIPSIVRHESDDSDEGLVMKSPTSPVDKKSKRSPAECEAIIKAKRAPLLNDEELIEMCLRGKIPGYALEKTLEDKTRAVKIRRAVVARTHATRETSSLLEKSMLPYEHFDYDRVYGACCENVVGYMPLPLGVAGPLMIDGQNYFLPMATTEGVLVASTSRGCKAINAGGGAVTVVTGDGMTRGPCVGFETLARAGAAKLWLDSDEGQRTMRDAFNSTSRFARLQSMKTSMAGTYLYVRFKTTTGDAMGMNMISKGVEHALNVMATEAGFEDMAIISVSGNFCTDKKPAAINWIDGRGKSVVAEATIPADVVRNVLKSNVDALVELNTSKNLIGSAMAGSIGGFNAHAANMVTAIFLATGQDPAQNVESSNCITVMKNLNGNLQISVSMPSIEVGTIGGGTILEPQGAMLDMLGVRGAHPTDPGDNARQLARIVAAAVLAGELSLCAAHAAGHLVKAHMSHNRSAVPSRAATPAPQPVPLPLPTPTSLAMTDMRERQTAAAARAQFGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3J7</accession>
    <name>A0A6A6P3J7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PSP1 C-terminal conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_206651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3J7"/>
    <dbReference type="OrthoDB" id="243127at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047767">
        <property type="entry name" value="PSP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43830">
        <property type="entry name" value="PROTEIN PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43830:SF3">
        <property type="entry name" value="PROTEIN PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="2">
        <location>
            <begin position="478"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="747" mass="81119" checksum="2E374D7B847431C3" modified="2020-06-17" version="1">MASYSQFGYQQGKNGRVGGAGGRMSFGVSGYRPTHVSPSTYRPESDRLPTPDSEAMASSEDEHDHVKSLVSASKPPQAVNPPKRRDSWLSDIQSSQRKPSLGGMSLASQCSQPPTPGETPGWTANARPLSKSGSLTWDTNIWSPQDTTARRESADLPFQIPLSPTRKTIRSQSYSVGQMERGSPGVMHKPSRKSMLGSEVTGDSGGDPAGLGKVIEDEDHESEGSDAGVRLPMHSDGGSSLLKQAAVENANRRVPPGRASITAATVQENPYAYDPNFGGFQSRRHSFANVPSDAVVHAPMARQIAALEEAAEDVPAIAGNYPNQQQHMAALQARQQQNLMNAASMSGSMGLSRGERRSPVLLYLVQFKCCRADVYYADPSNGLQIKKGDLMIVEGDRGSDLGQVQEVELTWEQAKRLRQENHIAHTQNLMLFSRNAQTLPEEAFLPPMKIVDSILKGELMGPSALHGDNGFDAELKPKLIKRHAAAHEIAQLKDKEGAEAKAKRVCQTKAQDHNLVMEILDAEYQHDYKKLTFYYYSTSYVNFNDLVTDLFKLYKTRIWMSSVNPAVFTPITALSSTVPMAAPPSSVPARGAHRATVSGYAPGQPSFGRGDFSSRAAQAGYFPAFENQHQQPAAFPNPSRMPQHPMMNTAGPGVPATAAGMREFLESPWGNENMQPGQGARRMWHGYEAPQDYLDATNLPPWAQRNFAVSPAAANGAGGPQVLAPQPQSHVAGTTESFLQNFRNLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4B1</accession>
    <name>A0A6A6P4B1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_301633</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4B1"/>
    <dbReference type="OrthoDB" id="27214at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025406174" evidence="1">
        <location>
            <begin position="18"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="3">
        <location>
            <begin position="150"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="2">
        <location>
            <begin position="336"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="736" mass="80689" checksum="BBFFAE9100F1759D" modified="2020-06-17" version="1">MRTVAFAVAAFAAAVVASDSDDPCGILSSSILSIMDENPEADLVLPAETAYNCLAAVPMMDPQADYELIEELKVFLEWNSHTEWLRNPPETWVNPPVDLISSLNNLEHRVLFDVDYDSEYAFQLDLNMLFVRAYDFHLVWTSDIQSVFLFEREFVPVSVSMNGSEFPQIYSLIDIVDPVDYTPSPVVKINGQNATEYIANFAVKTSAYIEDHARFNNMMWPTGQDEAVPNPFSKGIYYYGPTTTIEYANGTEQTIDNMARLSSAYSQVDWSAISSVEDFYDQICASQPGLDTDTPAKRDVSTLEPRSLLGYPEPLVNDSSGILGGFFLEEEGYESTAVLSLSSFSATNPVDYQQSLSDFLDLCRQQNKDRMVIDLRGNGGGSIVLGYESFKQFFPNVEHYGAANSRANEAMDIIGNVISSLTANATIANDTQIDNARGFDSQFNFRNWLTIDDGNFSSWDDFYGPHMTHGDVYTSAFRYNLSQPVEEQELNITGFGSQGVSLIRPFAHNNIVILQDGQCGSTCSIFTELMRTQGNVRSISVGGEPRAGPMQGVSGTKGANVLDTTSIQSFAAIPFQFAPDEATADYYDSTALGALFNGTQLPLRAGAGGSFPFRINFRNALRQGDESGTPTHFIYDAADCRFWYTPEMIQDVRNVWVGAAHNMWHGGACIDGSTNHPSSTTGHRNSSSADLGLQNNALTDDEEDCIGSFCDAAPMSAKAPVGLAALAALSVWILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4C2</accession>
    <name>A0A6A6P4C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4C2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16914" checksum="9F754AA3B34163A8" modified="2020-06-17" version="1">MQARAYPFSGAPVPEREELCTRLPRWLRPTSGPGCLKIDSSCFRQGCGLRACGLAGVCAWSVGAWREGRAADSSVLGPLAGGVADPALRHFPRTTTGTCRRHLSSGDGFQGEGGQRRGRDVSRRSWKPHVWREGQWLNADGRLQLSQRRIDWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4F8</accession>
    <name>A0A6A6P4F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_284026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4F8"/>
    <dbReference type="OrthoDB" id="5376138at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000088">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="60791" checksum="021DB9887562250D" modified="2020-06-17" version="1">MATTLPEREPAPGHYGEEAEYKEQESGRVSPEHVREDGKHELLESEAWDKLGYSWPTWRKWQILCVVFLIQISINLNASMYANAVDGISETFDVSKQVARIPQMTFLVAYAFGCELWAPWSEEFGRWPIQQLSLFLVNIWQIPCALAPSYGTYVVVRLLGGLSTAGGSVTLGVLADLWEPNEQEYAVAFLVLSSVGGSVVGAVIGGFVQEYKSLPWIFWVQLMVGAGTQLVHLVCNPETRATILLDREAKRRRKTGEDPNVYGPNELKPRLNMKEIWTIWYRPFYMFFTEPIVTWLSLLSGFSDALIFTFLESFNPVYKQWGFGTIGVSLAFIPLLVGYFLAYFSYLPSIHYFRGIRRKDPDRLTPEARLWWLLFLAPLETIGLFGFAWTSLGPGYGIPWIAPMIFSCLVGMANYAIYQSSIDYQTAAYGPYAASATGGNDLARDFLAGIAALYATPMYSNIPGRPLEYASTILACIAVVVTIPIYIFYWKGPEIRARSKFAESLDKSRKKSVVARKSLAGIDEKHLPGRRSTSGAQHVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4U0</accession>
    <name>A0A6A6P4U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_341366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4U0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21242" checksum="988F67D40C8A87D6" modified="2020-06-17" version="1">MNPPGTGKKHRVVIKPSQCGRMPSKARLFAFKIRTSIHHLTSHHRRNLHPPRGKNGPPTQSPANLSPSPAPSTKSPPLTQAPPLTQGSPSPPTRSLTKPSEPPSRGLERGPVRRTKRERTVCRSAVSTTAKPDRQGWDITRRRVRCRGGPKKGRLHEACEAARMGRAGAPSSGGRGQVLSGEKPGMSRRAHVMSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P596</accession>
    <name>A0A6A6P596_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_198224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P596"/>
    <dbReference type="OrthoDB" id="3783684at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="134" mass="15268" checksum="2C984F95350F6D95" modified="2020-06-17" version="1">MPGKHKNRKSFASPSRRRGQHLSEKERIQILTLYNSAKWNQSAIARELRIARTTPYRLIAKATSNASYRRYSLSEVAQDCRISACARVLAKAFEKERYFRRVAAKKPLLTEQHKRTGLPGQSSMSIGTLIYGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5C7</accession>
    <name>A0A6A6P5C7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_318148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5C7"/>
    <dbReference type="OrthoDB" id="89349at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF9">
        <property type="entry name" value="XYLOGLUCAN-SPECIFIC ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025455636" evidence="3">
        <location>
            <begin position="18"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="33718" checksum="66B485CDE4532D2C" modified="2020-06-17" version="1">MWLLTLFSAGLFVLPAAITVGGYIGIEYQKVFHGEGRPAPGTNNPLGPGPDGDGRIIETNTWCQKSFGITPFPGRYVFNPNQWGDPDDLGDLCMNITTDSGVSEDTLFAAGFSATWQYPVGPVDEPVHAFPNAKLLLPGDGPVRLAGLDGLRLDVSWSYGLGSYVHADTDSAVLGAAKVNANVCVDMFLAADAADAADPTRARYEVMVWLAAWGDATDPIGLPAGSQANHTINGTRFDLYYGDNALGQTVLTWLADRNTTDFIGDIGPLIHELKHHTGPDASDHLGYVAFGSEALYSFENVTFYVPRLAMDIDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5X7</accession>
    <name>A0A6A6P5X7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_340179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5X7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="66" mass="7472" checksum="ACC1E4D27FF89999" modified="2020-06-17" version="1" fragment="single">MLLEGAVTLPELDKHRERLCQQQARPAADPTPRCGEAARWPLAVLVALARRSYLDAVRVSMSTWWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P610</accession>
    <name>A0A6A6P610_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Polyketide synthase PksA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_190550</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000002">
        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000031">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000116">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="TesA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="240"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="1156"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="1521"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="1655"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1156"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1319"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1486"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1599"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1742"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1486"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1627"/>
            <end position="1641"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="7">
        <location>
            <position position="1188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="7">
        <location>
            <position position="1379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2041" mass="221229" checksum="FB7DC7CA85C7BE58" modified="2020-06-17" version="1">MLPLGVEAVRVAFRTGTCVGLKKDALEQSADSREAWSTIVTGTSEQAAKTALAEFHQEHAIPPTSEAYVSAVSTMALTISGPPSTTRRLFSNSETFSKNHYFPISVYAPYHASHLYSDADIDRILEGSPRKVFASYRPQSLIHSSSTGKCHTATNSLELIELMLSEIIREPVRWDRLLEECVSQVTAHSGAECSVTAIGVTNIANSLVSALKQGGQSNVSFKDYTSWNAAQDASLGRTQNDKIAIVGMSGRFPNAANHEALWDLLMKGLDVHREIPADRFDAQAHCDPSGKGKNKSHTPYGCFIDEPGLFDPRFFNMSPREAAQTDPMGRLALVTAYEALEMSGYVPNRTPSSKLHRIGTFYGQTSDDWREINAAENVDTYFITGGVRAFAPGRINYYFKFSGPSYSIDTACSSSLAAIQLACTSLWAGDCDTACAGGLNVLTNPDIFAGLSKGQFLSKTGSCKTYDNNADGYCRGDACGTVILKRYEDAVADKDNILGCILGAATNHSAEAVSITHPHAGAQEFLYKRVLANAGVDAHEISYVEMHGTGTQAGDGIEMTSVTNVFAPRHRQRKPHETLHLGAIKANIGHAEAASGINSLIKCMLMMQKNAIPPNVGIKGVINQTFPKDLAQRNVHIPTSQVSFPRNGAEKRKIFLNNFSAAGGNTAILMEDAPLDEGPIGTDPRTSHLVTVTARSISSLKKNINNLMKYLEENPGTTLPSLSYTTTARRIQHNYRVAFPVAEISKVRDALQAQLKDTYSPIAMVPTKVAFAFTGQGSQYTALGKKLFEELPSFRADIEELDSLARMQNLPSFIPLLDGTDVQSLSPVVVQLGMACIQVALARMWACWGIKPTAVIGHSLGEYAALHVAGVLSASDMVLLVGRRAQLLEADCTAYTHGMLAVKGSAESVEEVLGEKMTEIACINGPEETVLCGTVEVVSEANDLLAAQGFKATKLNVPFAFHSAQVDPILDSFRNVASGVVFNKPSVPVLSPLSGEVIRDAGIIGADYLARHARETVNFWSALATGQDEKVFDEKTAWLEIGAHPVCSGMVKSSIGGTPTTAPSLRRNEDPWKTLTTSLCTLFLAGVQIDFNEYHREFNDAHRLLTLPTYSFDDKKYWLDYHNNWTLTKGEAPVAPAKAPEPVVEQPSKLSTTSCQRIVREELHANSGTVVIRSNISEPTLYKAVSGHLVNGTALCPSSLYADMAMTVSDYIYKELRPGAAEVGYNIAKMEVTKTLVGLTPPPPEGQWLEMEASADMEQKTVDLEFYSVTPAGKRTEKHAYATVRYEDTADWLEEWARTQFMVQTQVDILEQKLQTGAAHKFLRGMAYKLFKALVDYAPSYRSMEEVILDGKNTEATATVKFQTTKEDGDYYMAPFWIDSLCHLSGFIVNASDVIDSSASVYISHGWGSVRFARRLSPEKTYRSYVRMQPAPGNISCGDVYIFDGEEIVGLVTRLKFQNIPRRAFNVMLPPKGSVAATKAAPAQAAPAKAAPAPAASKTKTLAPPPKKSAGKKPAKAAAPKPTNTITSRVMKIIAEETDVSESELVDGEAFENLGVDSLMSLTISAKFREELDLDIPSSLFTDYPTVGDMKKYFGQYDGGAPLHDTEDSDLSDAHSDVQTPYEDDNSTPPSSAPSSAASVSGKDEIEVEIEETTEVTGTGPSLARQIIAEEMGVSTAEIVDGADLAEMGMDSLMSLTILSALRERTGIDLPSTFLTTNATIEDIENALGMRQKPQEKVKVEAKVTAKPPRPSKPSKASKGPELSEVNKKLEVVRDLSKFPPATSVLLQGNAKIATKKLFLFPDGSGSATSYISIPNISPDMAVYGLNCPFMKKPTDFLCGIDGVSALYLAEMRRRQPQGPYIIGGWSAGGVVAYEVACQLLAMGEKVEKLVLIDSPCPVKLEPLPARLHHFFDQIGLLGTGKAGGTPSWLLPHFEYSIKALSAYEPQPMAAGNAPSTFAIWARDGVCGKPGDPRPPPAEGEDPKPMKWLLDNRTDFGDNGWGQLLGKDAMQFAVMDGNHFTMMRDEYGETLGQLIRQGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P650</accession>
    <name>A0A6A6P650_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ran-interacting Mog1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_300199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MOG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P650"/>
    <dbReference type="OrthoDB" id="10255285at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF0">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04603">
        <property type="entry name" value="Mog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21094" checksum="9FA66DEEC8785E54" modified="2020-06-17" version="1">MASFTSRELFGGAMTVSLPSEFADVSSIRQVPDNQEVWLDTNGFTSIIFDITERVDEQTASSDEDAMKFHFADIASGSNDDTKIWTAGSAQMTKLPTIPAYTMFATQTPPEGVRTGCNPTPDFTGIMLVLLRLKEQQTDLVITVNVPHTPGEYNKEEVDPSAGKNGPLLNAGLAARQKILETFEIKDLSLFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6A2</accession>
    <name>A0A6A6P6A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.157</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TSR3</name>
        <name evidence="10" type="ORF">BDY21DRAFT_370255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63300"/>
            <dbReference type="Rhea" id="RHEA-COMP:13852"/>
            <dbReference type="Rhea" id="RHEA-COMP:16309"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
            <dbReference type="EC" id="2.5.1.157"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.157" evidence="6"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6A2"/>
    <dbReference type="OrthoDB" id="10262062at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:rRNA small subunit aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002621">
        <property type="entry name" value="PRK02287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="9">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="8">
        <location>
            <begin position="78"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="395" mass="44159" checksum="BC4190533B6C1357" modified="2020-06-17" version="1">MVRHKKDNNSRGGKKQPRQFRPRRYNEGDGGGAHDGRPPYKAACWDLGHCDAKRCSGKRLMKLGLMRELHVGQKSPAVVVSPKAKRILSPADNEVLDQYGAAVVECSWKRVEEVPFGRIGGKCERLLPYLVAANPTNYGRPWRLNCVEALAASYYICGHSDWAEHILSSFSYGEAFLDINSELLKRYAACATEEDVQKEETKWLAKLEREYSASRADRRTARKAEDIWADGNMNRTRPDEEEEDENGEDGVVDDEGERNENREEADAQGSGEEDEEVKDRDPFDIPDESDDEEEMAELRRRVLASKPFANPEPSNSNGKNASQKVPAPEVSRPLEESDAESGSEIGGLDDEFDNIINATPVTDRTGIAAKQRSKRGDDVASVTFSRAVLNAPEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6U5</accession>
    <name>A0A6A6P6U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1776-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_281721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6U5"/>
    <dbReference type="OrthoDB" id="5308060at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013952">
        <property type="entry name" value="DUF1776_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08643">
        <property type="entry name" value="DUF1776"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="46112" checksum="A9F442B9024DD057" modified="2020-06-17" version="1" fragment="single">LGSISKDVRNFTADFADATDRHIDAVADSIRDVLASASWLPPSARPAPPSRPAPPSIFTPAPPPTMLRRAAAWLSRNRAIAAAVIAFFSTGGILLYRQKKAYGRKRRARRAANGARKEVVVLVGPPAAPATRSLMLDLERRGFIVFVAVGSAEDEAAVQRERRVDIRPLPLDVSDAEGAARAAERLVALLLQPQTAFQGAAPHALAFAGVVLVPDAAFPAGPTDAIAPALWADALNAKVLGTVAAVQALLPAVARFGARVVLVTPGIVAALRPPRHGVESAVVGALDGFVASLRKELAPRGVPVTQVRMGNVDFPAGNVAHHAPRPQLPLAGSSVRGSATRELHNAVFDALTAKRPPGVVRVGRGSVAYDLVGKWVPEGVVGWMLGVRMGKGRQGEGSGARSPVGLIEEAEVARGASADEGGSDNGLGSTGFWEKVEGGNGPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Z2</accession>
    <name>A0A6A6P6Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Z2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="19185" checksum="56351D5DCA2BCBDD" modified="2020-06-17" version="1">MEKKKRKEENEVKRPGPHGGHQSGAVQCPPLSVSRMLFMEYGSRWIAFRRREKGGRAHRACCLLLAACCTAAKPPRQSEAVAFSPAKRSQAQGGGEGLSPGLHTSELARGPVRSPRRRERQTVPSLFLETPRQLPAKRPRGRTNWREKKLGGTYCCIGPRAIVRHFTAPSHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P742</accession>
    <name>A0A6A6P742_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxisomal membrane protein PEX13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Peroxin-13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_384312</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="13">Interacts (via SH3 domain) with PEX14 (via SH3-binding motif); forming the PEX13-PEX14 docking complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxin-13 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P742"/>
    <dbReference type="OrthoDB" id="10037838at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11771">
        <property type="entry name" value="SH3_Pex13p_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000128">
        <property type="entry name" value="Peroxisomal membrane protein (Pex13)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007223">
        <property type="entry name" value="Peroxin-13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04088">
        <property type="entry name" value="Peroxin-13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SH3" evidence="16">
        <location>
            <begin position="288"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="360"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00065871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2459826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="425" mass="44958" checksum="1DB5F581E7D67405" modified="2020-06-17" version="1">MTNQGATTAATPTSATAATASGSQPPALPGRPDSLNSVVNRTASNYSSYNNATNRFGSSPYGYGGYGGYNSYSSPYSRFGGGGYGSMYGGYGGIGGMYGPMGGMGGMYGPGMGGMPGDPNNPNSLTQSFSQSTQATFQLIESMVGAFGGFAQMLESTYMATHSSFFAMISVAEQFGQLRHTLGSVLGIFTLMRWIRTAIAKLTGRPPPASSKELTPTNFASFTGQNPDGSPVARPSKKPFIFFIVTVFGLPYLMSKLIRALARGQEEEERKRMEANPQMYGGQPLDPSKLDFCRVMYDFTPDTNADNVQGVDLAVKKGDLVAVLSKSDPMGNPSEWWRCRARDGRMGYLPSPYLEPIQRRAQPAQITSASQAGSPAGSRAQTMSGTGSGPGSRAATMADAKKPPPISGKPGDIGVESFQKSQFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P788</accession>
    <name>A0A6A6P788_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ureidoglycolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_258077</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P788"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221">
        <property type="entry name" value="UREIDOGLYCOLATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221:SF1">
        <property type="entry name" value="UREIDOGLYCOLATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="221" mass="23051" checksum="6D00F46C2ED51EED" modified="2020-06-17" version="1" fragment="single">LHIPLEPLTRASFAPFGTVIENPARSSSSTSNRNPPPHLTPRAVPANQGTATKYLDVAHMQNHYEGARDARGGGVGGGGGGGAPSGRPARLSINMFACAPRALRGGSVLDVRLLERHPFTAQAFVPVGLAPGAGPTPAKYLVVVAPTVGEGGEGERREPKGRGAPDLSRVRAFLAHGRQGVTYAAGTWHAPMAVVGRETVDFVVVQWANGVSEEDCELLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L6</accession>
    <name>A0A6A6P7L6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting/targeting protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Carboxypeptidase Y receptor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15 17">Sortilin VPS10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_384392</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="443634at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.270:FF:000005">
        <property type="entry name" value="Sortilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.70.80:FF:000001">
        <property type="entry name" value="Sortilin-related VPS10 domain-containing receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031777">
        <property type="entry name" value="Sortilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006581">
        <property type="entry name" value="VPS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050310">
        <property type="entry name" value="VPS10-sortilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106">
        <property type="entry name" value="SORTILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106:SF27">
        <property type="entry name" value="SORTILIN-RELATED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15901">
        <property type="entry name" value="Sortilin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00602">
        <property type="entry name" value="VPS10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025426188" description="Vacuolar protein sorting/targeting protein 10" evidence="19">
        <location>
            <begin position="21"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1348"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1397"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="20">
        <location>
            <begin position="46"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="20">
        <location>
            <begin position="700"/>
            <end position="1337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2459950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1473" mass="165674" checksum="4AD88E5D49AFC718" modified="2020-06-17" version="1">MSALRRLLLPLLLLVAAALARPDPKVTEATFAVQPWKLLYFDDSEVVLFTDRDHGILHRSTAAGNAWEVVTDIPEGEVWEVFMHPYDRETAIVVGKAMDNWITHDQGATWRKFTTPETGSVSEPLIFHAGDPKRIIFNAYELCGFFTCMGNSYYTLDAFETPVEVLQKNRRACLWAKNDPLFSTGSDEKDKNRVLCIVEGRYSSDQKDYRMLISDDYFRANEFEPKIRDGRPVSGMINMANVKRYIVAAARAQGTEELALYVTDDTITWHKAEFGNYRIEEDAYTVLESTNYSVQIDVKTGKWVDMGVLYTSNSNGTYFTKNIEHTNRNALNFVDFEKIQNIQGIVLVNTVQNWEELEGTWSYAAKKVQSQISFDDGRTFQRLKVGDQDLHLHSITDQTNSGRVFSSPAPGIVMGVGNTGEHLKSYTEGDLFVSDDAGVTWKKALEEAHKYEFGDKGSILVAIYDEGETDKIQYSIDHGKNWTPAPLPARVRAQELTTIPDSTSLKFILVATKGGGSNLENAVYSIDFSALEERKCGDGDFETWHARVDGDGSPSCIMGHTQSFKRRKADADCFIKDKFHDPEPIFEDCDCTDADYECDFNFVRNDEGNCVLEGSLQAPEGACTNPDDTFMGSSGWRKIPGNTCIVRGDAKDAPIERPCTDTTGTTPSGEISHEITDFTADSFREWLYLERGDSGHGDDETILTLTDDTHDGRRLWMTSDHGKTWNTVEALAGENVLSIYPHQFSNDVVYIITDSSRVYYSKDRGDSFHYFEAPGSPTRENLQYLSFHARMSDWLIYTASEHCDFNGIDCHSTAHVTRNNGENWQALLPFVQKCQFVYREHRHNSEELVLCEQFRDENPRNPLELISSSDWFEHKTTHFDDVVNFATMSEFIVVAIKDPEDREFLRVDASIDGQTFAQAKFPHNFNVTHQKAYTVLDSSTHSVFLHVTVNFNEGQESGGIVKSNSNGTSYVLSIPDINRNGAGYVDFEKMLGLEGVAVVNVIANREEVDNGAPKRLRTKITHNDGADWTYLPAPKKDADNNNYNCGNDCSLHLHGYTERRDSRNTYSSPSAIGVMMGVGNVGPHLERIGDADTFMTTDGGVTWKAVMKGRYMWEYGDQGSVVVIVKYDVPTDHVFYTLDEGNTWKQYSFGREIKVQQISTVPSDTSLNFLLWGKYADGNKLATVNLDFSGLFERSCSLENAGSRDADYYLWEPRHPQGDSNCLFGHIAQYYRKKTDAPQQKCFNGRQYERLHTIKANCSCTRLDYECDYNFIRQNDNSCKLADGLDPLDPMAVCEENPDAFEYYDITGYRRIPITTCSGGLELELTSLPKPCPGHEDEFARKRGISGVGLFFAIVLPFAAAGAIGYYVWRNWDGKFGQIRLGDTRGYYSALDSDRPWIRWPVVAVSGLVAVVAALPMLASSAWRSVASRFGRGYGGRTYTSRSSFARGRGDYAVVDPDEGELLGEESDDEQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U7</accession>
    <name>A0A6A6P7U7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATPase AAA-type core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_336890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7U7"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="3">
        <location>
            <begin position="23"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="144" mass="16145" checksum="578FF30EB12D30DE" modified="2020-06-17" version="1">MHVLLGLPLTKIDCTQFFDEAGLFGPRAGYQRSTEGSQLNNFLAQNNGAPNIVFLDEFDKTTDDVRTSLLILFDSGEYYDRRNNRKVDSSKTVWILATNYGEKAIAKHSNQDGESSEAKDPLPKIQKALRDLFIKGLGVSIFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P860</accession>
    <name>A0A6A6P860_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_384466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P860"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="7">
        <location>
            <begin position="35"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="399" mass="42653" checksum="BBC9138B895B8116" modified="2020-06-17" version="1">MYTNANASKEAGAKGYANDGRTINHWAAPGPAEFDFRSDVMTVPTMSMLEAIKRCTLRDDVFSEDPTTLSLESFLAELTGHDAALLVLSGTMGNQVALRAHLQGPPHSVLCDHRAHILKYEAGGTASLCGALVSAVVPSNGVHLTLEDVKKHAVLSDDIHACPTKVIELENTLGGAVMPLAECQRISAWARENGILMHLDGARLWEAVAAGHGALKDYSACFDSISLCFSKGLGAPIGSIVVGSDAFIKRARWIRKSIGGGLRQAGVVAAPARIAVEETFLGGRLTESHERAREIAELWQSSGGKLSLPTVTNMVWFDLESAGISEEEFIKIAAKKGLRTLGSRLVVHYQISDDAIARLREVIEQVLPAGSVNGKNGVKRKRDAEDETATKKVNVGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P880</accession>
    <name>A0A6A6P880_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_184732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P880"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF149">
        <property type="entry name" value="UBID FAMILY DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="347"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="454"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="480"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="497" mass="54098" checksum="DF7AE773DB36CF24" modified="2020-06-17" version="1">MGGFDIAFQRELARNTWPMYGVGMFIILLRMYARIHRHGIRGLAPDDYLMLSAGALYTTLVVCLNIIATGGGSNLFLPEEYPTFDEEEIQDRIKGSKIVVLSEQAMLCVIYNLKACLLFMYYRLTTGSNQQRMVKWLAAYVFLAWVGTEFAFFFACRPFSGYWAVPPPNPQCTTLEHYAISQMCFNITSDLLMLGIPIALVSGLSLPLKQKIVLGIVFSMGVFVIIAAILTKYYNLSNVYDTSYMLWYFREASVAVYVANLPMIWPLLREWFPFLRDLSTATGAGPSAALPRYNKDGFTQPSDIRSATGTVGNASSSGRGHHRSKLSSLTSSAVGRSLGMHRLSSIEGAASGSSSTQDIKLQEGLSSPTTAAPAPAAQHHQHHRSAHPHFDAGLERLGIRRPATPESDERALHGGDVEKSAASGGGSGGAAGGNGGGWGIAPIRAQVHIEIERDSDSEVERHVGGAGRGGSQVGWQDQARQMREVRIEGGGEGRRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8K7</accession>
    <name>A0A6A6P8K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_369300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8K7"/>
    <dbReference type="OrthoDB" id="3932980at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025516546" description="CFEM domain-containing protein" evidence="11">
        <location>
            <begin position="19"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="12">
        <location>
            <begin position="13"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="108"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="211" mass="22009" checksum="96B474597E72AF64" modified="2020-06-17" version="1">MKFYTAIAAFMTAAAVRAQTLDGIELEGITTEEFQTLIPECAITCHDLAVETDGCDIDDYRCHCSKTGYIATVIDPCLPVNSTCTDDDVASFASLITPLCSYYNSTSPPESSSSSSSSSSSSTPCPTSTEVYTATTTECPESESTTYYVPPTTMSTSCETPYPTPNATYPSYSPSATPAYTSSPPPFEGGAAKVGAGLFGLAGAAFAVLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8R8</accession>
    <name>A0A6A6P8R8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Squalene monooxygenase</fullName>
            <ecNumber evidence="4 10">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_408433</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="4 10"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8R8"/>
    <dbReference type="OrthoDB" id="3061561at2759"/>
    <dbReference type="UniPathway" id="UPA00767">
        <property type="reaction ID" value="UER00752"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Squalene epoxidase" evidence="11">
        <location>
            <begin position="43"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="18663" checksum="F7901D4904CFC16A" modified="2020-06-17" version="1" fragment="single">LLSRSSIDFNCFCAEELLFVRTLLCCSWLCCKHRRAVTYLPPPRRIQPSLKALDGSRPKCIASSFLQPSQSRIPGLIILGDAMSMRHPLMGGGMTVVLNDVLHLRNLLSPCVVRDIADMDLVRKQMTIFYRHRKDLASTINVLAEALYGCLSKGTSKRVFRILSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P924</accession>
    <name>A0A6A6P924_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_165501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P924"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="21707" checksum="5551689628966CC9" modified="2020-06-17" version="1">MGTRHDRRKAPNSIITQQRAMVERGPKRPRRQGRLVSMTASAVCVSGARLVDTPRIPAIEEGVLSPPISWIPGQTSGSPKSKGCATRSPRRDGALTSEQSPSDHESMACGGRGWAASRRGIGPLGRQSRPLKVSLAGQFEPAFARASSDVAGRPGSFWGCCRVCGAQSLSVADRGSSEPSVSLSGSRVVQNAIGARQTHAGPASLHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P973</accession>
    <name>A0A6A6P973_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial ribosomal protein L27-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_280662</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P973"/>
    <dbReference type="OrthoDB" id="408933at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="101" mass="11784" checksum="09C8DDA8C9450DED" modified="2020-06-17" version="1">MFKPTAALLGGLRRLPLTTKQVPRGYYKGNRTGAMGRHTKHGRYVLNYMKIRTYVVPNLEDFVLTPFVTKRIERPKGYFEGESPTSARLYLQRWKQENGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P977</accession>
    <name>A0A6A6P977_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_335611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P977"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000722">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="191"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="624" mass="68229" checksum="27A09FE4983E8C31" modified="2020-06-17" version="1">MWAAGPRPGDLLRARLSPAWRPGLAIGDLPHGGPMGHYRPSPLSPTHWQAGPTGVSPATCLYQSPHLMSCRRGLATGFSIYCPWEEPSWADLFCLSCSFSCILACTDSETRYLLPCCGVASPWYRAPKRAPSAQNTSTAMSSSPTGSKVEVVAEKEDISKDLESAYAESQAGSPEYQARTKALLWKQDIRIIPLSCFIYLLCYLDRSNIGNAKVLNEPTNDDLLQDTNMTNYQFTIALMVFLVAYGTFEVPSNYMLKKFRPSNWVAFLMFAWGAITMGLGGTQSYGSVTAVRFLLGTFEAGLFPGLVYYLTFWYKTEERSIRVALILASATLAGAFGGALAYAIGHMNGTQGLSGWRWLFILEGLPSCLSSIFVFFLLPDYPETAKWLSIEEKEFATGRLELEGSKGHAKVTWADAKATLMDWRLYAHYAIYFGISTPFSSLSLFTPSITSGLGFEDLKAQLMTVPPYAVAYVVTLFASWSADHFNKRALHSAIFASIGAIGFLASAVLPPDAYQRRFGCLIVAASGAFACIPPLLGWLSSNLHSTGSVGLAIAINVSVGAPGQIAGVWIYKADEKARGYPTGHWTNCALLFFVAAGCLGLWRYYARRNARARAEGTGAREFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H5</accession>
    <name>A0A6A6P9H5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heme peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_384064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H5"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1103" mass="124461" checksum="6C2015605E36B4D9" modified="2020-06-17" version="1">MAAVTEKENQNGAPPEPASPSQLDEIRSEVDGKFKALVGLINAMKRPVPNETGDGTELDKEDYHTDVKDVVSNSLSDLAHLGISDIGTLIKLQRNKMTGDLVDDKTYLMEGLIKVAASLPNNSKNAKTITNEFLTQLWGDLDHPPLSYLGDQYGYRQPDGSFNSLLYPHVGKAGMPYARTAKPAIMQPAALPDPGVIFDSIMARKVHEPHPNRISSMLFYVATIIIHDLFRTDHHDFRKSNTSSYLDLSPLYGSNAEEQKQMRTFEDGKLKPDCFSESRLLLQPPGVGCILIMFNRFHNYVVEQLALINEGGRFTRPQEGVYGGHIRTMEEYDEHLFQTGRLITCGLYINIVLIDYVRTILNLNKTESDWQLNPRVDIPNGPPMGVGNQVSAEFNLVYRWHSAISERDEKWTIGLWKEMFGDADPKTMSMPEFFKKLRDMSDKVPENPPERPFAGLNRKEDGTYDDDDLVSILTESIEDCANSFGAQRVPEVMRVIEILGMEQARTWHVATLNEFRKHFHLTPHRTFEDINPDVAEELRRLYDHPDLVELYPGLVAESAKKPMVPASGLTPSYTVSRAVLSDAVALVRGDRFYTIDYHPKKLTNWGFATANSDTSVNHGCVFYKLFLRAFPHHFESNSVYAHFPLTIPSEMKTVLTTLDKDHVFNFDKPKKKGDEHMIFRYSTAETILSNQEIFKVTWGKAMEFLMGPAVKDFMLAGDGYKNAQSRKMMSEALYISDWDKEVKAFYETVVTQLLHKKSYKLAGTNQVDVIRDVGNLAHVHFCAELFSLPLKTEERPHGIFTEHELYLIMAAVFVCVFFDVDPASSFPVHQAAYKVTQQLGKLVEANVAAIKRAGVFSSVMQALFPKETKLKSYGIHMIKRLLASGMDVKELVWGHILGTAGGMVPNQGQLLGQTLDYFFSEGTEHLPELNRLAKEDTEEADKKLMHYMLEGSRLYGETGVFRYVTKETEINDGGRIIKCKPGDKIMINFRAASRDPDIFPNPDKLDLDRPIESYIHLGSGPHQCLGLPMVRISLTTMLKAIARLDNLRPAPGPQGKVHKVTKPFGPGDTLPESVHYHAYLTVNHDRYFPFPCSMKINWDGPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9X3</accession>
    <name>A0A6A6P9X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Xanthine/uracil permease family protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_280419</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9X3"/>
    <dbReference type="OrthoDB" id="431212at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005345">
        <property type="term" value="F:purine nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015853">
        <property type="term" value="P:adenine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015854">
        <property type="term" value="P:guanine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF1">
        <property type="entry name" value="XANTHINE_URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="555"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="555"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="595" mass="64547" checksum="7C81917C32FF2B02" modified="2020-06-17" version="1">MTWSSWVHDANLRIARSPVGRYFRLENSGHVSPLNADRFRRPQPKERKGTFFFTEIRAGMATFFAMAYIISVNANITSQSGGTCVCPPDSPDLCDSDQEYMLCVQDINRDLVTATSAIAALSSFCMGLFANMPISLAPGMGLNAYFAYTVVGYHGSGLVPYEVALTAVFVEGFVFVGLTVLGIRQWLARAIPASIKLATGVGIGLYLTIIGLTYSAGIGLITGYDSTPVELAGCPPETRDESGFCPNSEKMRNPTMWIGIFCGGILTVMLMMFRVKGAIIAGILLVSIISWPRPTPVTYFPYTELGNSMFDFFKQVVTFRPIERTLAVQRWDISGYGGQFGLAFITFLYVDILDATGTLYSMARFCGAIDERTQDFENSSIAYSVDALSISIGSLFGSPPVTAYIESGAGISEGGGTGLTAIFTGICFFISVFFAPIFASIPPWATGCTLVIVGSLMAKAARDINWNYIGDAIPAFITIAVMPFTYSIAYGLIGGIMSYIVINTIAWLIEKASGGRIKPPNKDEKDPWSYKIPGGFFPPWLVRVSKGKMDFWRDAEEGTARSSEEDRAVVEGDRVSDNSDVNVKASEAGEKPKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAA0</accession>
    <name>A0A6A6PAA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAA0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="553" mass="61988" checksum="EBAD3F91A8F6446A" modified="2020-06-17" version="1">MDSNLGSSDVISISSDDSSAKTTFDPPNPHLSFWYSIGDWVQRHTSPPNNTAAEESANSMPGCIPGGAAAHKQEQQQKQQQNGLAEGFNDDANTEKYTGQTRKSSPGKTPSEFQEAETASTTSFTGERKGQNFSASTWEMESTFNSADSDTESSIINGFSFAHSEDEGPVEKVVRQSDVAALAEQLESMKGAMLQQQADERSARESLVQTFAHIMNELEQRHNARIEKLDAESHRARKERNSLRNKVGRTEDWVLECLAGIDGCFSRRLGNLSDEQKAIKQSISDLKEHRLEPLNEAVNQQEEEATQLKRDLTQARKDITTFVQRNAKSPRNNADEWQNELEANRTQMDAINGTLESLQTHLCSVDSDLKSENEELKLELDFVKKRLHGFREVFNSEGWQEVANNGKRMDKVYGNFKKFKEQLNNRYCELMHAMTGQMITIVNKIMDKLSTVSGQGLEKSVDGSCEGVKASESLLRSVERQAGQIEKLETAMDSRAKVGRVRDLETRIAEAWQTQKLEAENGGQCDVDCLYESSDEEEEEHHYGEDEGYGGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAE0</accession>
    <name>A0A6A6PAE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_360934</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAE0"/>
    <dbReference type="OrthoDB" id="4451586at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="736"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="835"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="839"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="859"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="961" mass="102953" checksum="0E17ECC95CE48460" modified="2020-06-17" version="1">MSESSTPSDTADRPALPPKRKASAAGLDGHGNGTGRSVKRRASKACQCCRARKVRCNVTEHGAPCTNCRLDEVECVVSESRRKKKWAKDAEASTSKTASASHASQTRKLASREALDGLSNFSATSRKSRESPVRVKEHVPHSIYQSHGQKNNLGGSSYSRRMTVDGPTTPAPLSLFGQMPMSADSHASVFSQFASKQAPSVSLPPYIKPLPARIGADEITYLEKKGAFTIPSDDIRNELLRAYINFVHPYMPLLDLHDFVQTIDQPDGSCGKVSLILYQAVMFAGSAFIDMSHLRGAGYNTRKEARRGFFQKARLLYDFDYESDRVSLVQALLLLTYYYETPDDQKDTWHWMGVATSVAHTIGLHRNPERSTMDAKRVKLWKRIWWSTYMRDRLIALGMRRPTRIKTEDYDVPMLTLDDFEIGAIPDTVSCVPADCVVAKDVDRQRQLALMCISKAKLCLCVSHVLSKQYCVLNNNQGMVNDRTTMMLLPKKFDPDTCDVQMCDEELRRWQEELPAEARYSETSSGLASIDLCKALLHMVFFTTLSALHRPQVLPSANPTQVSSPAASPAGSPSLLEVSRKNVRRAAAAITSIAQKLDQRDLVRYLPTTGVTVLLPAIIIHLLDIKAPDEATRRASLRGFCQCMAVMGKLRDLYSAADYSTAFLEAAIRKAGISLAPFMAHPPSCAASAAGAAAAAAMPLGASANSMKARHSPTVDDIMLTGRQMGMDPPSALFSSAARELTPPPDAHSQRLSQTPIPNLGGGTVTDDGAVASPFHGGVSIPSATAGGGGELPRTIAGNATQLPPGIHNNGAGAGAGAGFADAEVVRRLETFLASTPPESDHHSEHAAHLSDGEHEGFGHGGGGEGQHDGIGSGGMADQEAVMNAALGAAGAGAGERAGHGGMVGSLGDLLTDFDADLDFDSIFNLDGTGDGFSFDDVSCLQGESSGFTADVDCMKAGLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAM4</accession>
    <name>A0A6A6PAM4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_361013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAM4"/>
    <dbReference type="OrthoDB" id="3935484at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17860" checksum="6E4B999600CFAADB" modified="2020-06-17" version="1">MSDPLSVAAAAVQLLDVLARLTKSAYAFIAALVAASAELRALQRDLARLGHLQKAVRETMCRVETRLAKQPQGRSRAKAGIDEDTDTLRHMRDDLEACKDDLGRIEHVLSKPYDGTRSVFNRFGKRVKFVFDEKEVQRLSSRIRSHLSTLSLWLSLIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAX7</accession>
    <name>A0A6A6PAX7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_361125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAX7"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="85"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="402" mass="40623" checksum="73B18EB803DC5C9B" modified="2020-06-17" version="1">MASEPSWPFGAAFSSVGLWLGHNICAYGKTEIMLQLIHLAAATGFLASVGHTFAHPDLVLPRQSAPTALCPDLQIPSGSGGRKIAVVIDSSSSNHGTDPDDLRVAAGRSLADVLVSTAEATADLQADQLAIVDFDSSATVIYELGDPAAADFSSIDSFGGTSIVSGVEAAVDELTKPESGPTADRAGIVVLTDGQGGSVASLVEQINRAIGLGIRVSFGFLAADAEGAGDPDVLAAILSSSGIYSAFDNAAAQQGFVNLVVSHGLTNGGAGDGDTSTLLAGLSIAAKVDPDGPNTFTYAAQDGEDLGFTVTSVTAGNLTCALSDASGAELATASSDESGLATINVTAPATSELQLSVSASNTSEDATFLVMVNSSLGIASHSEVKLTSETSKKHNVQMDRMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB61</accession>
    <name>A0A6A6PB61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_369152</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB61"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000326">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.150:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="365"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="484" mass="53672" checksum="DCF9F1E0516875DC" modified="2020-06-17" version="1">MSLDPPTYILSLQNNTRARPISWEGAVRAKTISDADLNKIKSIDKVRKEQRRQTVEQDLPGFTALLLGGPKDGSPSIFQSAAKRPDIVQYMLVLVGDCIDEIPPLVTSMLKHPSPFKPFLPLLKSTSSNPEDPIPLLASSVLSSLISAAVIASSSSAPSQKHIDEALPQLYGYVATLVKSTDAGLQDIGVQEYSALLRSTRAREIFWDMRDTTLAPLMDILRAAAGTSKDGDSTLWSGGSSARTVTETGISGGVGIQLLYHCLLVVWQLSFEGEMVGDGLHDEHDILILYVQLTRISPKEKTTRLLLSTLRNLLSTNRTSLLPAAVLARLPALLQNVAGRHLTDLDLLEDLQALREMLDDYTKTQTTFDEYAAEVRSGHLRWSPPHRSEAFWRENARRILEAANGELPRKLADIMAKSWDHDRQVLAVGCNDVACLVREVPEKRPMLEKLGLKTRVMELMQSGDEAVRWESLRAVGEWLRYSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBK1</accession>
    <name>A0A6A6PBK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_83008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBK1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="18827" checksum="DC922AF2790039F9" modified="2020-06-17" version="1">MHTCAHMSLRRRIFETSPVEAPSPFPVYTQKHRRPGRERTGALSRRKKHNRHSSFPFQPHVHAAQTVFGGNKKGSKFGGRERPQNWAAYLGSVRRRGVGWGTFLGPKYHGTGPPSGKSRCPVYVVRTRCAAACTGSSRTKIGSGSCGTRNRSYVQVAESLSGLCQSLCAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBQ4</accession>
    <name>A0A6A6PBQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBQ4"/>
    <dbReference type="OrthoDB" id="3792540at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF1">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="284"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="498" mass="56410" checksum="C4D3715D24756A0C" modified="2020-06-17" version="1">MNGRITKARTRRSREKPSKALEEKLVDALPRSHQQPPANRGPSRDLKPVPTAKRQFDAISSEKDPLPAKRTRLMRTDTERLGVDEEIEKVAKTTLQQPKPNPPKLPYASFLKDFLDPVHSHPRPVSLHAAVSEWLESVGSDREKCCRSDGHLYRSDDDPVSRQPTKSVPEMGYTQDANGFLAPPTPASTESLSYQVDADAGAITPSDVPSSSRSGRSLVEDPYYRYRNLALNNIFMRNPDEKFPDDVANLVRHVGKDRNSPGPSPDQVRCDAGLYQLEMETVDEPGVEKYFHTHTPPDPKPSGSLKRTEKQPMAKHTVPNTTRSNLKVSNPIPDLLYGYNCYTAFPQQQAQLISMRNEPMANTQSLTYPFFVIEFKGNGGDLWVATNQCLGGFMSCVNMAERLNEQLRKCKSDMIQAIDSPAFSIAMNGTEARLYISWKHDELDYYMRKVESFALQKPKYYIEFRKYVRNIIDWGKDKRLNEIQASLDKLDLTLSVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBT9</accession>
    <name>A0A6A6PBT9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ASST-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_261639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBT9"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025452855" evidence="1">
        <location>
            <begin position="24"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="55873" checksum="7D47D2C970F24B83" modified="2020-06-17" version="1" fragment="single">MVLMVPNLILGLLLGTLSTLAVADIGPYINDAAFQNKQYGLFPTQNFTSNPNVLDIPIFNIRHGSAEQGSANGYIFLAPWGGIVYHPGPMIFDSKTLALVWSGEGFGTTLNFRVQKYKGTDYLTFWSGSFGSGGYGEGHYYMLDSSYEIAYNLSAVGDTGGDFHEFFISNDDTALVTLYHLEQADLSEFGVENGWVLEGRFQEIDIETNELLFEWRSTEHVSINETYQVPKALTGNDSSLPFDYFHINAIDKDEMGNYIISSRNTGTLYYIDGDSGEVIWRMGGRLNEFEDLSNGNATNFIFQHNVEWYPGDHSRLTLFDNHDDEEIPGEFNSRGIILKYDDDAMTAELEQEFVSPNNISAASQGDVQILGNSNAFIGWGQQPVFSEFTADGELLWDVQFGILDNSTVQTYRAFKMDWVGRPNTKPDIAVGTGEDSGKLFMSWNGATELKSWALLASNGTAQMHDETFFWQTVTATGFETTVTVGDQARYVIAVPLDGNGNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBV7</accession>
    <name>A0A6A6PBV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_82679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBV7"/>
    <dbReference type="OrthoDB" id="4135672at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046670">
        <property type="entry name" value="DUF6540"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20174">
        <property type="entry name" value="DUF6540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="18422" checksum="729F89EA8DC8D883" modified="2020-06-17" version="1">MAGTYRVYIIRERLSIQDPDMPSPRYHTSILVETKPETGGGIIHQVTGDITSAGGMWYEHEFRDKPQESDDFISKELLGVTHASTHPVQWESVLRQVGAPPQQKAFNPKTMKTEPFKTLQPLTFYEPREPRQRLIKCTEWTLEGAIPALKNAKLVQENCSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC55</accession>
    <name>A0A6A6PC55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Vps5 C terminal like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_331822</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC55"/>
    <dbReference type="OrthoDB" id="271164at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07627">
        <property type="entry name" value="BAR_Vps5p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000013">
        <property type="entry name" value="Putative Sorting nexin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000022">
        <property type="entry name" value="Sorting nexin 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035803">
        <property type="entry name" value="BAR_Vps5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="205"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="576"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="630" mass="68085" checksum="A472AB865E32A3B9" modified="2020-06-17" version="1">MDLGDEGSSPWGDVPSSQSLSQPPTHSKEPDSSAGNSPSASKTSDALAASTASTSTAPVKSPGGRSRGPGRRHGGPPQPARSTRLEAVDDALGPLGPLGDSFPASGGSAQGDEPPAPPSKEQSFTASTTSPTAAGAGGRSISRPTSSRASSVRGMMDSVNLEDDDEDEPVARGPRVPPPVQPPAPGDGARRATQPSVSIEQAAKPTFSIAVGDPHKVGDMTSSHTEYAVRTKTTSKAYRNSEFTVSRRYRDFLWLYNQLHNNNPGVVVPPPPEKQAVGRFDADFIESRRSALERMLNRTAAHSILQHDADLKLFLESETFNVDIKHKERKEPNLGESKGVFGAIGLSVGGGTKFIEHDDWFHDRKIYLDALESQLKALLKATDSVVAQRKSLSEACGDFSASLHSLAAVELAPSLSGPLDGLSDLQLRIRELYERQAQQDVLTLGIVIDEYIRLIGSVKMAFTQRQKAYHSWHAAEAELQKRKVTQDKLLRQGRSQQDRISALAADVADAERRVHQARLLFEDMGRLMRAELERFEREKVEDFKSGVETYLESAVEAQKELIEIWETYLMQLDAEEDGAPFGHPSPPAGVIATPSKDIGAPSSEAGDQRPESRDTMGDDTVATESTDEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCI4</accession>
    <name>A0A6A6PCI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWR1-complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_398517</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCI4"/>
    <dbReference type="OrthoDB" id="19740at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="11">
        <location>
            <begin position="172"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="105"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="380"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="544"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="571" mass="62801" checksum="0946F27251DA8C0F" modified="2020-06-17" version="1">MASSKDVRDIMGLEAGAAPAATAPNKKKGGGGGGLGRRPTGMNRELLALHGERAPPVAVVDVQKTYLAKPQRHFRPSPWEWSPFINPARKDGLVLKHWVRKPHGKSVGGEVSQAVDGQGDTPMAGAEGEDGGQNKEGTNGDVVEHQIPLAEYPYAKYNVEIDAPAFSDEEYDLYMRSNDWSREETDYLIGLVKEYYQRWPVIADRYDFQSQNTKAESQDGTLEDKMALQKAGAPPRTADDLKARYYNICARVMELHTPVSEMDPAEFALHEMLAKFNPAQERQRKEVAEQLLNRTREEIKEEELLLAELQRITTNQTRFEAERAEVRARLEAPRAAPGSNQYDSSTALAMLFNQLFQADRSKKRGRLSLPADALGGHSAAAATAAAGGPGQTPTSAEAHRNSLLGSGGSARKGSLVHGSAAHQQHGPGHHQPAPKEPSRTLAPRAAARFGVSTHERLSSGVTFRTDRLQKLRQAKSAIQTQKIATALAELGIPDFVLPTTRVCEAYAALVGKITKMLDLRKVLEKQTNELKVLRAERGIVMAEKEEGEGKEEKEDARKRMTRLLRNPPILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCM3</accession>
    <name>A0A6A6PCM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCM3"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="741"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="801"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="842"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="893"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="910"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="955"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1098" mass="118745" checksum="82A6A856497F75F9" modified="2020-06-17" version="1">MRVTCAPESRICRRLAAMASSRRAQRRPAHEAERQAGVAPPYRPLLPACAAAPAALLLPPSLPPAAALPSAATPPSCSPSPLPSPPLRPRSPSSLRRLRSQSPLSCLSDSSAAVHHDSVSFRVNPQPVRAQTGVSSCETAFARKRGPPAPDPRDAPSRKRQRPGRAKAVKEQAPLKPWDRSWKLDANSFLRVFHHCDPRTLSKLRRVCRLFKGLIDGENKSIWRYSRENNYGDKLPPPPAGLDEDQYLALVDGVGCQGCGHKNARKTYWAFLKRWCEACFTTNVVKAQAAAAQDHLAADHRILDCVPSGIVDSWGAYECAGNDSISNFRRAGHGRYTVYRVADLANIAARRAAFARTDDFLAKDDAARKAALDGWIAARKAENEAYLDHIMRIEKWERDALAEKQNRNKDFKSQRAKYYQQEAAKLDPPLAPEALQLIPAYNQAVKILKAPSQRSWSHLLPKILSERAKAEAIVRAEKDEAKAATNRWDEYKRYNTQRMCRQSAEERLVLALADVAIDKMTEPLTHQLINEQDFAILTLKEIWTLYDHIPDKDKPKPAFPRLGPDGHYELTMQDACLVFDDKILPMLDNYIGPEEARTASIRKSARMYRCPGCVRNDVKGRFSFKALFPHIKDRHAGEIGHFQLFRRAGPAAKPGNAEFHWCAIPWTRNIPMLADHQKPTGRWKADDETDYVASTKVAAADLGPRWDRDDYAREARKALAKIMDNASVSIGGGGGGGGGSQMAASTLTSASSSASQPHHNQHHHHLLQHGGFAGPSSSSSSSSSSSSSSSPSSSGVRHPHAMNPPTHAHAHAPPSGLTRLPPLHHMQHQHAPPHQHQHSHRPQQQGENQPRQQQQQQQQHHRPYHPRAGFDVPDISFLPDPLRRAMFHRHQHQQFLQQRSQLRQQHHQRTCSSGTASTAPPQSFPTTSTITTTHNAHNSPYGLAAFHGPPAIIRPPSSGSSPAFGSGSTSSTPAPASASSSMSAAASGLAATGLPMPGRASSGASGPSATATAAATATPAPAPAPTQPSAAAGPQRRSDASGAFSPAGFRAINAGSRRSGGGLGGSGTGLGLGFGLEVGGGGAAEGGGGEERSVVTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD18</accession>
    <name>A0A6A6PD18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_314381</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD18"/>
    <dbReference type="OrthoDB" id="269919at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="134"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="517" mass="52930" checksum="5CACFB17EC85B085" modified="2020-06-17" version="1">MPSMAVPPTPGLASFLKSLNANPVETSIEHFISLLKRRQIRSSRACAVATTHLLIQVLAPATPFTALLARIRQVGARLTAAQPRELAVGNMVRRVLGLVREVAEESPESASGGGGGGDSTADAKPLSHRPPLPSSISALSPLKHGATAPAETTTGTTTTTTTITAPSPLRETHAGRPPLPTQSTSYAPGPPAATSLFGIFSRPETPSPASTPAGAQSPSRAAAHMPGGAAKEHRERGSPSSSSGGMSGGETLSGLREMLDELDSAAEQIAGVALDHVHGGELILTHTASATVQRFLLAAARKRRFTLVHVESGPNDDGDTRGAVLMGSGRKAGAAPGGGGGGGWGGGGPLGGEDDEEAGAPAEERFRPLTAAGVSVVLVPDAAVFALMARVNKVVLAPHGVLANGGLVACGGAATVAAAARAHRVPVVVVSPVFKLSPLYPFDVAELIEVGDPGRVVGFGEEGATRWLGEVVDVVNPVFDYVKPEFVDLYITNLGGCAPSYLYRIVADHYRVEDVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD51</accession>
    <name>A0A6A6PD51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sec63 Brl domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_3024</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD51"/>
    <dbReference type="OrthoDB" id="1734229at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000039">
        <property type="entry name" value="Protein translocation complex component (Npl1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="105"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="501"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="644" mass="72653" checksum="1F10126C21BD91A4" modified="2020-06-17" version="1">MSQDYNYDDQGQFFPYFVTTITALITVPVTYSWLKPSKGLENTAPRIQSDFKPEHADLIEGQRRKQKRKERKVKRMLISIGGWLVIAWMVYLMVVTARTTPKLWDPYSVLEVSMSATEQEIKRRYRMLSLTMHPDKVQPDPEKNLTLEAINDRWVEVTKAFKALTDEEVRNNYLKYGHPDGKQSFSIGIALPKFIVSEGNGKYVLLLYGTLLGVLLPYLVGKWWYGTQRYTREKVLVASAGNLFREYKDDVSVAGLIGMFSSGEEYKLLLKGSKGTAGVDKLEQRILEEPGLSNVGASLSAKDRQKFQEMDDLVRKKALGLLWAYLGRVELDDAALNDEKFEVAPIASALNESFTAIALAYMNTRAILSAYRASQHLIQALAHGAPPLMQLPYFTPAVVKAAEGLERHHLTIQDFMNIPADRRKKLVTAPGLLKDSEYETAMSVVSQLPTLKVDKAFFKVVGERFVTPGSLVNFVVKGRIIPPGTMNVPQVNEKDLEDVDPAEGDLDALHGRKKGEGTDSENPVQPPLAHAPYFARDYSPRWHLFHADSKSGKLAVPPFTFRQFAKPIFDENGKPTFNVQTMRTQFVAPAQPGRYTFVMHLVCDSYIGMDMKMDVVLVVEDPSKAEVMKDEEDISEPEEVWQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDG1</accession>
    <name>A0A6A6PDG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDG1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="184" mass="20047" checksum="8682C088E2754750" modified="2020-06-17" version="1">MEELTESFGRTGKMEGKKAALEGCMGYLRHEWESKGARRSSVAGPSNQGQAGRGWLFVDAVSWRPSATRFPWGLLQPPQIFVPVSGWSEPQGNIRKRGALAEAAPPGRGGAHSNVVIFESAFLRRHHRFGGAVATAPTARARRRQVCRWGLAGRTSRDSESRSRDRLGAAVAVTEASRQRPLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE11</accession>
    <name>A0A6A6PE11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_278557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE11"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521:SF0">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25005" checksum="BF14F733C0D50BD6" modified="2020-06-17" version="1" fragment="single">MPLVYFSRLLNRYPELVPDKLRELDQLRLETIPASLQQRAKNGDAYLTKGEVLQLMEWKLKHGTFRPGLLNRVASNSSEAVESTTRAAFYTYANSTGSSESGVKTSAMASMSHPPLSTLIAALNTLTTLNGIGPATASLLLSTLAPASVPFFSDELFRFLRWETGGPTGSRGWGRKIAYSGKEYADLAERAWEVCARLGGYVDVGVRELEAVAWVLGKEEIVLDQDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEV4</accession>
    <name>A0A6A6PEV4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit</fullName>
            <ecNumber evidence="3">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_359957</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="3"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEV4"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03796">
        <property type="entry name" value="GT4_PIG-A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000053">
        <property type="entry name" value="Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000026">
        <property type="entry name" value="Phosphatidylinositol N-acetylglucosaminyltransferase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039507">
        <property type="entry name" value="PIG-A/GPI3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="12">
        <location>
            <begin position="42"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="11">
        <location>
            <begin position="217"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="480"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="515" mass="58307" checksum="4941118F72EC76AA" modified="2020-06-17" version="1">MPYNIAMISDFFFPQPGGVESHIYQLSTKLIDRGHKVIIVTHAYEGRTGIRYLTNGLKVYHVPFFVIYRESTFPTVFSFFPIFRNIVIRERIEIVHGHASLSSLCHEAILHARTMGLRTVFTDHSLFGFADAASILTNKLLKFTLSDVDHVICVSHTCKENTVLRASLDPLMVSVIPNAVVAENFRPLNYPTNLTDGFLTSPTEIRPPHPPSHHLGPHDTITIIVISRLFYNKGTDLLIAAIPRILAAHPNVRFIIAGSGPKAIDLEQMLERNVLQDRVEMLGSIRHEEVRDVMVRGHIYLHPSLTEAFGTVIVEAASCGLYVVCTRVGGIPEVLPAHMTTFAKPEEDDIVAATSQAIERMRSNKIRTERFHDQVKVMYSWTDVARRTERVYDGISGVLSEEEFYGYRDAGSAAGWSATRGRAGVQSFALIDRLKRYYGCGIWAGKLFCLCVIVDYLLFVFLELWAPRANIDIARNWPKKRQQSVEPSAPVEQRQEESELARKRSTRHREKRREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF29</accession>
    <name>A0A6A6PF29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bile acid 7-dehydroxylase 1/3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_330166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF29"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF12">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_1G14540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="29580" checksum="679348CD80B56EE1" modified="2020-06-17" version="1">MSAKDDVALNDFTNIFSLEGKVAVVTGGSRGLGLHSASGLLQAGCSKVFITSRKAAACDEAVAALNALPNLRPGARAVSVPADSSKTPEIERLVAEVRKHTDHVDILFANAGATWGAPFDEHPDHAFEKVLRLNVQSVFFTVQKFAPLLAARATVASPSRVITTASVGGLVVGSYGNENSTPAYAASKAALIHLTRYLAVELGPRHILSNAVAPGFFPSRMANEIMRRQGGVEKLAAENPNGRLGTPEDIAGTVVYLASRAAGHANGTCITLDGGKMWAIAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKM9</accession>
    <name>A0A6A6NKM9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001737">
        <property type="protein sequence ID" value="KAF2452235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKM9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10455" checksum="D5F72087336151F3" modified="2020-06-17" version="1">MGGRGAVHYHGGFFAGGCCFHGATIACICRIHILERFVFDWDWTPSVGFWIPPWDVWTNRNCWVLTLVLLFLGVFLFFLILLSMETVVILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKX3</accession>
    <name>A0A6A6NKX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase/oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_359472</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKX3"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="555" mass="61375" checksum="79D2D73205545CB5" modified="2020-06-17" version="1">MSKTFTKDEVAGHKKADDLYIVVEGDVYDLTKFQDEHPGGKKILQRVAGKDATQQFWKYHNEAILKKFKAKLQVGSLDTKPKPAAAPPTPPATPPAAEKQTVKPAATPGAVAPSPGPDASEEAEALDPYGDLVPYADPSWYQSYHSPYFDQSHADLRAEVRQWIEDDIMPNVTEWDEAKAVPDSVYKTMGERGYLAGLLGMKYPTHLTGGKHVAAVPPEKWDFFHELLITDELSRAGSGGLVWNLIGGFGIGCPPLVKHGKKSLVKKIVPEILKGEKRICLAITEPDAGSDVANLTCEAKLSEDGKHYIVNGEKKWITNGVWCDYFTTAVRTGGEGMNGVSVLLISRDMGGVSTRRMDCQGVWSSGTTYITFEDVKVPVENLIGKENQGFKVIMTNFNHERIGIIIQCVRFSRVCFEESVKYAHKRRTFGKRLVDHAVIRLKLAHMARQIEASYNWLENLVFQCERMHETEAMLKLGGAIAGLKAQATTTFEFCAREASQIFGGLSYSRGGQGAKVERLYRDVRAYAIPGGSEEIMLDLSIRQALRVHKALGMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLA1</accession>
    <name>A0A6A6NLA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001713">
        <property type="protein sequence ID" value="KAF2452287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLA1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="125" mass="13871" checksum="F9B9D215F12DDD18" modified="2020-06-17" version="1">MTSLQRLFFVSYCLPLSSTSLIHDMDAITFHVRRAAVLLFTFFISVLANGYANAYYDALGGSSPPGVLIRGLGWLAASTVNSKFQVPPTPAEETWLLYVVLAPVVAGHVWNPFEGRERFSWAKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMB6</accession>
    <name>A0A6A6NMB6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMB6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="104" mass="11553" checksum="02FD71D3D8EF375A" modified="2020-06-17" version="1">MPQTRPRNTFFQNPGSRRRQSGAHATPWPLSTSARGFVKPVSRNCRHSIPDADLQFAPAVTIFVNKIVRMDLPRTTRVAAAAHQPQKPNIFAFSGLLVSNTTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NME3</accession>
    <name>A0A6A6NME3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_311420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NME3"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF131">
        <property type="entry name" value="GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="51"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="711"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="462"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="825" mass="92926" checksum="50F77FB181B1AE28" modified="2020-06-17" version="1">MAGEHSDLNSDDTETAGSPHPLATDSATNAEIKELLALINRLEQLQIERTVLPLPKIVVVGDQSAGKSSLVEAISEIKVPRAAGTCTRCPLQIKLARSPNQAASWQAEVSLHRTYDYNKSPRERSKYSKHWELRDQPVSIKLCSVSDRDDLEDVIVRAQAATLNPSVDPHVFMQPGADIAYSETKFSPNVVCINVEAPGLPELSFYDLPGIINQARHGEEYLVHTVRRMASEYMQDEKTIIMLACAMEGDIQNCTAASLVTNVGATRRCIGVLTKPDRIPAGDPVDQWEEVLNGRKFGLGYSYFVTKQPSTEDLNAGISHQRAREAERVFFATKEPWATRFSQYKERFGTHNLQDRLSELLAKQIFDALPDIANKVEAKIKEIEAKLACLPGPPRNAYHTVHHTIYEFSRYIADGIDKQEGSFRRAWKIIMRAFRDTDLGLAQPLLKPITTAEFEEHKEIKNQLPITIDDEDDEGEVNKRQPITPSNKNPRKRPANGNGRPLSTPTTNNNGFDGRVIAGPKMPGEALGIPISCKIFTLEEIKEKLNDFADIALPREVNRGAVRSLMGDAYSYVNAPIDRFLLRLRYELNDLLDDAFSRTFDRWRSTHLWKNSGTFLKDDVVEGYVKRQAEFAALLGRMTTAKPVTGNDHIFSILKNEALAILHDKRFEQRAELHLDRAELYGKAIKDKESKIKKKDPKFVEELGSDPEEDQVQVMAEIRAFYISASSRFADYVQESVECEVFDDLKTTIAGKLQGALGLDGTNEDIQRCEELLAEDPQREYERRHYKAELESVQKAREHLAALMNRYGIFGQVNVDLEHVDIPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN27</accession>
    <name>A0A6A6NN27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_142134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN27"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15403" checksum="9261E7A41470963E" modified="2020-06-17" version="1">MKRLTGQECDEVGLVPWSAKIRGPFSSAILRFLATAAGFAAVVPTVDRPAWLQFLLSRFLLLTIVRFYLWNGRAWGVAVAVGLMEVWWLVLSILFGLIFSFLLFLCVCIFPFFLVLLPSYSPSYSFFFSFASPFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN30</accession>
    <name>A0A6A6NN30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vps53-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_154228</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN30"/>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.110">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 53, C-terminus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038260">
        <property type="entry name" value="Vps53_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="9">
        <location>
            <begin position="610"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="786"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="786"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="853" mass="94213" checksum="921F24BB35F93870" modified="2020-06-17" version="1">MSAVPSSSLDSANYDPVSHLNSIFSHPSTLTSVAATAAHLHTYQDDLDADIAALVADQSASDTESVARIQSAKAELSELFARIEGVRSRAMQTEEAITAMTADIKRLDGTKRNLTQSMTALKRLQMLTTAYEQLRGLARSRQYRDCAQLLQAVIQLVAHFKSYRSVEQIAALSRNVSELQRELLEQVCEDFEVCFAKGEVSARRGVLSEACGVMDALGEHARARLVNWYCNTQLREYRHIFRGSDEAGSLDNISRRYSWFNRMLKTYDSEHAAIFPHHWRVNEQLANAFCESTREDYKSILQRSMRRADGQTLDVNLLLSCLQETLDFENSLERRFTTNESRSSIDTMMSKDENKMTFGQAISEAFEPYMSLWVDSQDKQLATLIPKYRQQPLRNADEDFTAQLVIPSSTELFHFYRVNLAQCAKLSTGSRLLELSKTFAKYLDQYSQQVLFYFLSERPGPQGPSVEDAILILNTADYCYITCNQLEEKIKGRIDEEHKSAVDLQSQADAFMGIASAAVRALVRKVEIDCEPAWREMRATPWSKLESVGDQSTYVAELLRRVKERTAEISKLLHKQQYARAFCDNLVDGLVNSYIANIVQCRPVSEVGAEQMLLDSYVLKKGFTELATLNEEPGTQPPAGFVKRVNITTAKLDPLLKTLQVRPSPSEALVQAYLIHIADRSDTNFRKILDLKGITRKAEQGPLIDLFLAHRASPAHAGLAQNSPLLTPLQISSTSGAAGGSISGLGSTSTPSLGSRAFDASSFGSALINAARDGVDRFGSPALGASANASSSSGGASGVPAAQAASPPLAQHGDGGAAHGSTNLNENLRNIGKFFRRDVGTFGRFGRREEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN92</accession>
    <name>A0A6A6NN92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone deacetylase complex subunit SAP30 Sin3 binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN92"/>
    <dbReference type="OrthoDB" id="510958at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20011" checksum="D89EA3A8D222215A" modified="2020-06-17" version="1">MPPAKSRVVHDDSKLDSASLKDKHSGSGNTSGGRGRRNGTAATANGSSLKEVMPAPTDVTTTNGHSVQSGQQEPTGISWPNEELPLLQQYRIAYRLDTPAAFNNPLAHVIMGNPGIGRYSPTMAHKKSKRRVSKDQLALAVRKNFNGLAVNENDVIVDVLYKMRTQDKAFRKRFPPPQPPQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNS5</accession>
    <name>A0A6A6NNS5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit DUO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein DUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_402483</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DUO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNS5"/>
    <dbReference type="OrthoDB" id="5599235at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013960">
        <property type="entry name" value="DASH_Duo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08651">
        <property type="entry name" value="DASH_Duo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="168"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2453356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="26785" checksum="B1214CD6C721E2CE" modified="2020-06-17" version="1">MSTPNLDLSDSDADALFDSPLPDAKDKAKLKAAEAIGGQDNGVQSKDDSGAGTAEGGSKSAPRESGFDAEQAREAALRRELASVRRVNEVIESAVESLEKAKRNMETVSATTHSTTTLLNTWTRILSQTEHTQRLILNPAWPGATQDLADAESERAAAAEAAVRREAEERARREAAARRAEEEERRREAAAAAPGRRGSVKVRGTRSRPGIGGAGKASGSGYVGVGGQGGRGRGVTVGRPTASSGTSRGRGRGRGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNX4</accession>
    <name>A0A6A6NNX4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras small monomeric GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_367261</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNX4"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000654">
        <property type="entry name" value="Small g-protein ras2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="222" mass="24719" checksum="95CA36D911902EE4" modified="2020-06-17" version="1">MVGNLALHRLVVLGDGGVGKTALTVQVSLNYFDHAYVPTIEDSYRKQVQIDGQACVLNVLDTAGDEKYAVLRDQWISDGDGFVLVYSTSSRASFVRIEAFYRQILRVKESELESTFPDSPPRARPPIVLVGNKSDCDTEREVSTSEGAALARALGCHFFETSAKSCVNVDDAFYVVVRILRKRRHRTPRTEKEGRIKARRVASQSSLSRAPGREREPTCIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNZ9</accession>
    <name>A0A6A6NNZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">INO80 complex subunit Ies4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNZ9"/>
    <dbReference type="OrthoDB" id="4093188at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013175">
        <property type="entry name" value="INO80_su_Ies4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28061">
        <property type="entry name" value="INO EIGHTY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28061:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08193">
        <property type="entry name" value="INO80_Ies4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="31420" checksum="B4E70E98794DFED5" modified="2020-06-17" version="1">MPPAGSSTKASAKTSPKSRIVSLQLPATLLARFPSDVTNSSTAKSSAATSKKSSSSSSASSAPSSASTPAANPPPAAAAPSPSAQPSDSNAPTPAAVNGAPPAPDANGLAPPPATNGTTTKRKGIPGPKPGSKRAPALGPDGLPKPRGKPGPKKKPRLDDPSAPQPAIAQKLGPKANQGAINAGLRALDRSGKACRKWERKGFQVKSFTGVVWSVPSWRAPKKQLALPATDENAVAVNGVSAPNGEVKSDITALSGALQLPSDLQGGGGSNNVGSSAVASEKSNAGGDPDTPMGGTSAAGNNGQGAEAASSPAVQPVEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP21</accession>
    <name>A0A6A6NP21_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_124690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP21"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="242" mass="25665" checksum="DCBA86C831D3B254" modified="2020-06-17" version="1">MPERGDLGAAALLQGLAQGFRVTGGWQLKGAVSLGARCRVAAGGGRLPGGAARAKGCCNGLGPSALMGRALMTEAATLAERAHLFTTARPRRSFRRTEGPRCSASDKSLLFPPLRAGDSLTPWPRAAKRRPRGGRAYRGIKDQATGQKPRREAGWLLVAGRGGSRAEGRSRAPWRAGTHMWRDPPGPRRCCPPALALPPARRCSPNPHPPLGPSDDPAETYMAHAHAHAPEGPRRSRLSIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPC6</accession>
    <name>A0A6A6NPC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BRCT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_292782</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPC6"/>
    <dbReference type="OrthoDB" id="251770at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18433">
        <property type="entry name" value="BRCT_Rad4_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000010">
        <property type="entry name" value="DNA topoisomerase II binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="103"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="317"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="424"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="533"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="546" mass="60592" checksum="C44F9FA9FBC89E99" modified="2020-06-17" version="1">MLIDFKALAQSPLQGVVLCCTSIPPERRNKLAEIARQMGACHNYDLTGDVTHLLVGSIDSQKYKYVAKQRPDVKVVLPEWIDAVRESWMQGGGTDVAALEAEYRAPALFGLRICVTGFEDLTERQRLQQCVNENGAEYHGDLTKQVTHLIVASPTGKKYTYARQWAVNTVAVEWLLDSIERGMVLEESFYDPLMDPADRGRNSWNREALAHASRSKKRPLGDGGGLGRRDAGSRRKLRRTASAKLESQSYALWEGIAGASATTVMPEGQLRDTTQEFSLRNGQSPNNASTRTKKVPIRTSSPELLHSDGATGNPVPKRHGIFQGRLVFVTNFDDRKNSLVSGHLSANGAEVILSTEELEGFTGDDLQRGYLILPHNKPFGDAQIPKAAEPMQIVTEWWVESCLARKMLLGPSEGLFLQPFPHARVSAGFEGVTICSTSFTDLDLLHVTRAVNLMGATYDEWFKESHHILISNTPRPSAEKVSFAQENGIPIVRKEWLLDSIAKGVKQPFDDYALFPLSRNPIERGDSAVISEQTRDDSLLSNENHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPJ9</accession>
    <name>A0A6A6NPJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Basic leucine zipper transcriptional factor ATF-like</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">B-cell-activating transcription factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_123067</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPJ9"/>
    <dbReference type="OrthoDB" id="3783440at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000837">
        <property type="entry name" value="AP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23351:SF14">
        <property type="entry name" value="BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23351">
        <property type="entry name" value="FOS TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0221">Differentiation</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="13">
        <location>
            <begin position="126"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2453646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="323" mass="35034" checksum="5C25308C5943C18B" modified="2020-06-17" version="1">MTFLGFEDNGPDSMLGISQSGAFAGSTSPELPTIAYDTDTLKPGGVNHERGQPILGGKEPHSYEKKHGQITPPNDLSPFSAANCSLPEGADGPQPPEPPPSKRKKSSGTASISDVSAPASQTDSTEDKRAKQLEKNRMAAWKSRQKKKRTTEELKNTKDELELENVRLKEDMKHYRNENNQLLNLLLQHISCGHEDINNYFKAKAARLTSQNNFYANLTINGPNPSLGRASECDDAAADEQVVMSDLFLQHHLSQCMSPQGAPAVGNYATDSPEDQLAQRQFYNVNGGEHVGRAKVSGDDASVTGSPSPKLEGGDITDDFLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPY8</accession>
    <name>A0A6A6NPY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_125858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPY8"/>
    <dbReference type="OrthoDB" id="9971601at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF2">
        <property type="entry name" value="METALLO-HYDROLASE_OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="46155" checksum="29B4A16E9070B707" modified="2020-06-17" version="1">MRHKTPPPSAATTTAALTHDVPASPSAQLRDSLSSHLRARLRRRSPLLHHLNADTSWLLQIPLPAVAARRRTRGARRSGGSVASNAAAGGRGTARAYYNILIDPWLKGGQSDVAWWFSQQWHVEESAVRSVGEVEEVIGRVEAMVGEAAEEDGSEDETHDEGGGRRTRRGRIDAVAVSHEFTDHCHKDTLLEVDGDVPVFATEKAAVLISAWDHFRHVITIPHFTSGTSDWRALSLPPLPSWLSISRVVSASHDALHYHSALLIAFNTRSSPDDPASTDDDDENTPATALVYTPHGLPSSPETLAPLLTASPPLAFLAFLHGLHDVSLPAQQLNLGARNGLAAQRALRARYWIGTHDEVKKGGGLVSWFLRRAKETVGEARRALEVGARMGIGGWKGGGVVDAEAGANGEGEEECVELGNGESLVLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ38</accession>
    <name>A0A6A6NQ38_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_113984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ38"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="21200" checksum="F72F3CD76AA982C8" modified="2020-06-17" version="1">MQLDGRKLRLACNAVACNAVGAWLTAQRHMYPLIGEHGRRREPFARQSCSPGTRPGRTCRRLHVPWHPGRRGHDTSVRLLAACGPAPLAEARGSVQTGLDELVSPQTFGAFPAASHSPPLQAPRPWRQGPAPPCTEPLVHLVSQAPTCTHELSVRRSVDRLESATYAAGIAARLRDLVAWPQRRRPESGSSAPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQT5</accession>
    <name>A0A6A6NQT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PUL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_291843</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQT5"/>
    <dbReference type="OrthoDB" id="10265988at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.870:FF:000003">
        <property type="entry name" value="Polyubiquitin binding (Doa1 Ufd3) protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000236">
        <property type="entry name" value="Polyubiquitin binding protein (Doa1/Ufd3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="232"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="7">
        <location>
            <begin position="371"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="8">
        <location>
            <begin position="500"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="788" mass="84106" checksum="D93F93AA360E1A04" modified="2020-06-17" version="1">MGDFKLSASLEGHEDDVRAVAFPHASFVLSASRDATVRLWKQLSSSPPSYDNTLISHGTSFVNSLAYVPPSSDFPDGLVVSGGKDAIIEARAPGKPPHDNADGLLLGHSANVCSLNIGEDGRTIVSGGWDAEARVWQVGRWEATAVLQGHQGSVWAVLAYDRETIITGCADKLIRVFHPSGKLLRTIKGGPDVVRALCKMPQGHPSGAQFASAGNDAVIRFWTLEGHQIAELYGHESFIYSLAVLPSGELVSSSEDRTARVWKADQCIQTITHPAISVWSVAACADNGDIVTGASDRVVRVFSRASDRQADPDSIQQFENSVKSSSIPQQQVGNINKEKLPGPEFIHQKSGTKEGQVQMIREPNGNIAAYQWSMTGQQWINVGTVVDAAGSSGKKITYNGQDYDYVFDVDIEDGKPPLKLPYNLSQNPYEVARKFIADNELPVTYLDQVANFIVTNTQGATLGQSQTQAPGSDPWGTESRYRPGEVDAPSGPPPAASRPKALPQTQYLSIATANLKTISKKIAELNSQLVDQGRKDLALNPHNLSVLDALAKQLDQAQASAEAAKSPANPDGIDLALRIATSWPPDNRLPGLDLLRLLATSPTLAAHTSSDEDTIVDILAKSGVFEATAPTNNTMLAVRVLANLFTTNEGRLLVDGSFEQVRAALKPHIDAAADGKVPNRNLAIALATLYINYAVLAVEAATGGGDEADRPLELLEDLVSLLKGCGDAEALYRALVGAGTALSTGDLVRAAAREVLGLPDVVGRAERVGKEGRIKGVAAEIRDILKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR35</accession>
    <name>A0A6A6NR35_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_291802</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR35"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="119"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="626" mass="68541" checksum="E46FA233A24295D7" modified="2020-06-17" version="1">MVHCLISPTKLLFPTLKSVQTPSDSCWPPPDAWNALNDTISGRLLHPFPPGSVCYISAPTYDAEACAPLLAGQWFDPTFHAENPLDINHPQWAGNPCPPVWPNGTSVNGDPTAGADGCSRGRYPEYVVNATKPIHVQEAVRFAKQWNLRLNIKSTGHSFQGRSTAPGSFIWTRHIRGIEFHSEWQSEYCPSSSLNASIEFHGEWQSEYGPSSSLNASEYQMAATIAAGETDLSVYEALATHNAFVVGGAEPSVGIVGWFTGGGHGYVSTTYGMGADNVLEATVVLPSGELVTTNACQHPDLFFAIRGGGGGTYGIITSVVMRAYSQPVTTTVTLFITYTAPGNDSTARPKFWELMANLHSLMPDLSDGGLQGYYIIGGPPTFPQLMFQGLFMLFNKPNGTVEVLTAPVVSILNVAMAEGIVQYQTAVETYPTYWQMYEAKSGGQPVATGGTYLGSRLLTKRALTEDLGALAATFEEIGPTIDGVSNPILIGHMIANRDNRNLDIGLNPAWRDAYIHFIVVEVWPDNSSPSYIQSIKDDITFNKTHALRQLSPGSGAYFNEADPAEPDWQYTFFGQNYARLRTVKERYDPEGLLWCYSCVGSEEWVDREDMRLCRVQWANGEDRPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRT0</accession>
    <name>A0A6A6NRT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRT0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="97" mass="10267" checksum="181A3C55FDA8CCA7" modified="2020-06-17" version="1">MVLDPEKAPIIAHVAIARQPTKRAQPLFHLSPHSPAHRRSPRLAVPATTQTPTRTIARIALGPASQPRVGRQTAGSWPAKLSSAGASAVLSTTQTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS04</accession>
    <name>A0A6A6NS04_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sld7 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_353127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS04"/>
    <dbReference type="OrthoDB" id="4205424at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041260">
        <property type="entry name" value="Sld7_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18596">
        <property type="entry name" value="Sld7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sld7 C-terminal" evidence="2">
        <location>
            <begin position="367"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="56428" checksum="1A007AE0B7D437B8" modified="2020-06-17" version="1">MDIWHGDICLPDGSYIRDIWLRSPADCTYAPKIKSLAFLAFVNTYDIPPATYISDRLEVTTSTPETAEYFQSNLVERCPENMDPECPWWNRRSRSSPISILTEVTLSDDACGEGEGDSGPQYVANITNVLFMAVTPEIEYNLKDLEDETSNSGAAFASSSAATGAHSSTSASDDEQLEIRIVAQPMSDDVLIAAELLKSLPVPDQPGPGQDSFGVSFCLWCLNSPRLLCPLHTSGNDDAVSTDDEEQPSSCPPQSSVFDHAAEQRRKAKRRGGLSISAAVAASSQQATGIPSLHSPSPRVTSSPGAPLHARPSSRSPSVSLPPGSAVGQSTGASASRPQTSRGPSGLTRVESVTAGEEESPATALEAKNKDAVSRVVMAGLRLYGMQPRSSRRKKSLVTGNSVNAAQEEEDRRKDEEFKLVYHQVYKGAVFAFRAYMRTIPLQQHTDHVRETVDQLLAIFCSDPMASSTKSEDAPGQERTLSVTPGGRKRLYGEDPTEVEKSPFNQKAAEEATLMAVGRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSC4</accession>
    <name>A0A6A6NSC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 14-3-3 family protein ArtA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_291032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSC4"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="5">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="29492" checksum="91F0437A831E4855" modified="2020-06-17" version="1">MGYEDAVYLAKLAEQAERYEEMVENMKTVASADQELSVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKGNEAQVNLIKEYRAKIEGELAKICEDILEVLDQHLIPSAQSGESKVFYHKMKGDYHRYLAEFALGDKRKTSADKSLEAYKAATEVAQTDLAPTHPIRLGLALNFSVFYYEILNSPDQACQLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSSEAENAAEPASEQKDNADAPAPAASEEPKPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSE5</accession>
    <name>A0A6A6NSE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_106299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSE5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21622" checksum="A5249C7CA628C6A0" modified="2020-06-17" version="1">MDDAINIATSSDIEKLQAQIDGLLVKVSKLEAKSAIQDGFKAKTNSLPTTALGPGSFGLISYDTVASKSPEELAKMKEDIVELMAHLTNTRHSEYESWRPMVECFSKRYGLGLNFELDMSGKWEGVTFSESWDFAGTKALPFVDRMDYLWKSSASFANRHHEHSRVTYMWWVYSIRQLAVALGVGKVKDKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NST2</accession>
    <name>A0A6A6NST2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific expression protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NST2"/>
    <dbReference type="OrthoDB" id="3837730at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7998" checksum="A809AAA2A6DD3941" modified="2020-06-17" version="1">MANNPVGNTSPHVNAQSERRRSSATQHFASLQALKRNSQHTDGTQRRASMMEQQAKPGMLGQMWNKFTRGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT67</accession>
    <name>A0A6A6NT67_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_351936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT67"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="603"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="971"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="981" mass="111074" checksum="D6E4D5290B6CB004" modified="2020-06-17" version="1">MTHHRNSVPTMEETETSSERNASPPRSPLSYSPRRQRSFLRSRPQVRRSSKVDGYESRSPSDASTDYRYGPSNEAELKLYEEAKKHAIRKGGTVYLPSEVWGKYEGYSLNSHLCVSLTSTSFFLDNNAQDTDSHSPGSHQPSQELSKSSDHARARCQHIDRVAIINKPLEQAIRQVNGNSVADVFHRPPFRCIVPYEQKFREMYRDKEAEFKRLAAEHPNHPSISREDPSVPESMTFTTKVFRDGDGANLEEMDRTRILLDGLKALIAFLDHDIVDLVETHRKIMSRTIEKIPFPYLWHLFVPGQEVISTKPVYQVYRVINVMDGRRALAEGSETTGAPGRNIVEALTIQCMFFSFDGQKFGPTEWTISIKPYDNDLDINSLEAYPLWYKGEGLEKDLIRRGKKFAELVQVTHRRYKGLSVGIDGLERPEEIESDVIIDPELGFRDPSSKIEASTFLDFRSLSTLGQDAQSREYLSGSTSITFEERDVLKSRMSGLLNETDLLDVKQHYEMDRNHWILLPYSVLGYVLLNRKWYLLNIDLIEEVDTVKEGGPDGFDDLILPPGHKDIVRALVKTHARAQRTPTGSDMKILSQRELDLVKGKGKGLIILLHGAPGVGKTSTAECVAANTGRPLFPITCGDIGGTTAQEVESNLEKFFDLARKWGCVLLLDEADVFLSERQKGDIRQNSLVSVFLRVLEYYSGILILTTNRVGEFDEAIKSRVHCPLYYPPLNKKNTLGVWQMNLERLERKNKGSESKLPVVFDQKEIMDFAKRHWKAGNRWNGRQIKNAFQTAIALADWDNLKREDGSEKRSSAHLERRHFEKVAEASAHFERYLTIVRSNQSDQARARAHEWRRDDYADELSERARRKKKSTKGKKVATKIPWPALSSEDDSDSDTSDSSSATSETESESEPVKKRRGHKRGKNKKAKKTLSDSDGKAKNAGKKKGKAKEGKPVDGSKKKPSKKEEDEADSASSDSDSGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTA8</accession>
    <name>A0A6A6NTA8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_351623</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the U5 snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTA8"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17945">
        <property type="entry name" value="DEADc_DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000322">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057479">
        <property type="entry name" value="PRP28/DDX23-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25430">
        <property type="entry name" value="DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="235"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="449"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="601"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="12"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2454798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="639" mass="71256" checksum="08F2CF5BABDDB0DE" modified="2020-06-17" version="1">MRVPQGPAAMERVAERAEEDGGRPGGGRDRGGGNGRADRAAEQRARDAEEAEAALIKQRYMGADTNLSTFSAKKKRKRTTDKKFNFEWNAEEDTSMDYNPLYKSKTEANFFGRGRLGGLSDDKMEDVARKYARALEERDVQAGKERAKMMLEMERRRREEAQRNAIDKHWSEKRLDQMRERDWRIFKEDFNISTKGGSIPNPMRSWDESGLPKRLMEIVDSVGYVEPTPVQRACIPIALQSRDLIGVAVTGSGKTAAFLLPLLVYISELPALDEFSKNDGPYAIILAPTRELAQQIEIEATKFAKPLGFTCVSIVGGHSIEEQAYNLRHGAEIIIATPGRLVDCIERRVLVLNQCCYVIMDEADRMIDLGFEEPVNKILDALPVQNEKPDSDMAENAAVMSQHIGGKDRYRQTMMYTATMPPAVERIARKYLRRPAYVTIGNVGEAVETVEQRVEFVSGEDKRKKRLHEILSCGEFTPPIIVFVNIKRNCDAVARDIQNMGFSAVTLHGSKTQDKREEALEGLRKGTKEVLVATDLAGRGIDVPDVSVVINFNMATNIESYTHRIGRTGRAGKSGVAITFLGNEDADVMYDLKQMLQKSSISRVPEELRKHEAAQQKKSKGGGSKALEDSGAFGGKGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTP4</accession>
    <name>A0A6A6NTP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_94689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTP4"/>
    <dbReference type="OrthoDB" id="5357075at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="405" mass="43075" checksum="CA9ACCA1988EC23E" modified="2020-06-17" version="1">MQPRLNSAPSQDNETHQPSAAQQQHAQEQQRRRREQLHQAEMQQQDELAHLFTGLTFSPHAPPQPHEQPPPADPTPPPPPEHHHQTPDNQPITYISQHYTHSAHIPRASTTTSSDAPIPPAPAPAQASASASTSPSPIPSPISDASLTDIQMAHLLSAHAVDPAALFPTQIELFRRAPPDQRARLLELWRIAPPRYYGGRSIASASASAGQADGTMEWPRTSLALEEDMARVRWERERGAGAAGRWGEVMEDEQVADRGPEVSAELLADAEVHPGIAGGVGANDNASNPSAAAAAAAAAEPYIVSGYEALARRDYEEQAGRTMLGESTRYNQATDPAFNRVAGGWGGGGGGGGGGGEWQKNTWVQGHGHGHGHGGQPGGMLMDMENQYGSFAAAREGGDGDVMMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTS0</accession>
    <name>A0A6A6NTS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">biotin synthase</fullName>
            <ecNumber evidence="4">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_387374</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="4"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTS0"/>
    <dbReference type="OrthoDB" id="2414104at2759"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000011">
        <property type="entry name" value="Biotin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="BIOTIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976:SF2">
        <property type="entry name" value="BIOTIN SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01060">
        <property type="entry name" value="BATS_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01278">
        <property type="entry name" value="biotin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="109"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="400"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2454958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="45603" checksum="CE093079518AF290" modified="2020-06-17" version="1">MAGKIAAKISDPGVVGPMAVTALSLTRKNDAPGHGGVTRRPFSTVQDVPVIPTPASSSAAPSGVLHDALNAAKPRTNWTKDEIAEIYNTPLMELAFSAGTLHRRFHNPAAIQMCTLMNIKTGGCSEDCSYCAQSSRYQTGLKATKLSPVDEVLQAAKVAKDNGSTRFCMGAAWRDMRGRKTNLANIKKMVEGVRALGLESCVTLGMIDGAQARELRDAGLTAYNHNVDTSREHYPNVITTRSYDERLATIGNVADAGIHVCTGGILGLGEKAADHVGLIHTVATLDRHPESFPVNALVPIKGTPLGDTPPVPFDAVLRTIATARLVLPTTIVRLAAGRNVLPEEKQMLCFMAGANAVFTGEKMLTTACTGWEEDKAMFERWGLRPMASHETMGSRTEMLRNGPSENAPSVNAAIGASRAKEEGQVSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTX7</accession>
    <name>A0A6A6NTX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Soluble quino protein glucose/sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_290276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTX7"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051262">
        <property type="entry name" value="SMP-30/CGR1_Lactonase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572:SF4">
        <property type="entry name" value="LACTONASE DRP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572">
        <property type="entry name" value="LIPOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025602268" evidence="1">
        <location>
            <begin position="19"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="2">
        <location>
            <begin position="31"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="462" mass="48683" checksum="C954A17399601527" modified="2020-06-17" version="1">MIGRLVIALAALQARALAQSCPSLTANYPSPSVADGFDARLIVQDLTKPRGMVFDHEGNLLVVESGKGITAMSLSYGDGSCVSVQEKKTIVSDTSLNHGIELSSDGNTLYASNSDMVFSFDYDAGSMTNTSSGKAIVTGMASDDLVTRTLLIPRSADDKLLVSRGGDDNMDFGTVDLDSGRSQIRIFDLGGDDAVDYLEGEVLGWGLRNSVGVGENPRDGGIWSVENSVDDIERDGESIHADNPAEELNYHGILSDDDDDNAYLGANYGFPLCYAAWDVSEIPGGDGLSVGDQFAIGEENATVNDPFCAQDRQAPRLVFTAHTAPLDIKFDSQGDNAYISFHGSWNSPDPVGYRLSVVPFGPSGQPTAPSTSTTAARPILSNEDLDSCPDDCFRPAGLAWDNAGRLYMTSDSTGEIYVLVRADGAPVDANRESGAGAAVGGRRSAWAVAVVAGAAGVAAWFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU77</accession>
    <name>A0A6A6NU77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase catalytic core-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_307470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU77"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000207">
        <property type="entry name" value="Glycoside hydrolase family 128 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025509601" evidence="1">
        <location>
            <begin position="21"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="27"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="32670" checksum="0F36321A952B0D7A" modified="2020-06-17" version="1">MLPATLLTIVISSSPLLVHATSSTKRGLCYVPSDEHASDDDLWTASSTPLTWYYNYQSTPSSALSSSGLTFVPMLWGATDGVDSGFYSAVKAQLDAGEAISHVLGFNEPDGESDTGGSDMPAAVAARAWQAELEPLRALGVKLGAPAVTGSPGGLEWLDAFFEACDGGCAVDFVPVHWYGNFEGLASHLGQVRERFENKSIWVTEYNLPDAELDETQEFYNMSAEYFDRLDYVTHYSLFGAFRSDDSNVGPNGAMLDSDGDLTDIGSWYLGGAATGNEPDSASAKLGAAAFAGWGVLLVAVAGAWSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUF9</accession>
    <name>A0A6A6NUF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_373462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUF9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="35293" checksum="415EA09897B02D57" modified="2020-06-17" version="1">MPPRTPQQLTPTTRIERQLIYEPEMTSEEVEYLLTAIGSGCAFRELVLSVAYDVARQIATLEDVERLLGAMGSKGIVHQLASYLRRAVRHLSGVMKAKAELLKRRKKGQKEVIELARLLISDPCGDAAGPPREPSKMIEPRDIYDEQLEPKQVATPEKDDERQIPPEGADAEPSTSQEGPAPPRRTREEAHQHRHHCSQHDCDSSPRYILAAHPGPSSPRCFASPIAVLLTPPTDTQPDPSSYLPPYDDLHYAAQDYCVCCGAGGPHMRPPDPAKYRTRRARATERRGAGPGTERRRKSRRGHSGRGGGDHAGCVKDGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUK5</accession>
    <name>A0A6A6NUK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_72345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUK5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="16974" checksum="E639EC40EED695CF" modified="2020-06-17" version="1">MIENETTWWRSRLSQSSCRASRERRRKQNPSERPARGKALEGCPRSETMESWREQGIGHRGHEEFRRAASPLLARLSYSLGHMPTSCPCDLDRLSCSEVSGSANAQPQTARLARDSAGGPSPNLSVLPWAEDRRTKRPSGAKAKAQTCCQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUW0</accession>
    <name>A0A6A6NUW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_351032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUW0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="73" mass="8347" checksum="E3FD8AC18F5355EC" modified="2020-06-17" version="1">MDLVLFRFLLVAAGAELVLGFGYIRGGGGRWTGRARLRSMWQWERQWPGGMARPKSLYFIFFFSSSSSLLRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVY4</accession>
    <name>A0A6A6NVY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_288869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVY4"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="45"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="22653" checksum="34AABF679415A249" modified="2020-06-17" version="1">MTEYRYHRLSLCQIRLLTLLSVDQSIDEPICVSISPVTLSQRPRYTAISYRWGTPTLAQKIHCCNDVLFVTPNLHSALRQLRAQSLVGEEIVLWLDAVSINQQDDIEKIARVLLMGEIYKAASRVVIWLGPEAYQSDLAMAWARYLADEATDQAVPPDASSRLTPFRFKDYPIDPHVSPKSFFCLLSRPWFRRVWTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW74</accession>
    <name>A0A6A6NW74_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_65120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW74"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025430189" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8917" checksum="3F4F46E69F213E75" modified="2020-06-17" version="1">MKHVSNYLFFLFCLSRCLWRSMVNQLHMVYHNIIKEASIRRKTGIKPITKTLLGLVQPTAMTLLLTINAMLCPENLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW92</accession>
    <name>A0A6A6NW92_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_422765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW92"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="367" mass="40052" checksum="3A453516AF974CAD" modified="2020-06-17" version="1">MSFVGALVLRGCGRQAPAQLAGTGRVRLLLGAHSRGRAGKTRATGRIKRHRRDMRGMLRGWGSWIGSPASYLSVMMADRSERQVLGTCVVHSPHHLFSFERDKVEDNPPSSWRLMMIDADVDESRQLIRRGRAGPGRRSRPRSRSRTVPLGQLNTATHCHSRCSADTKPPSARDEWDEAEQKVEWTRAQTAGAGARGAGNDRCYMHRYSRKRRGARMGRRLASEIWLAAGPSPRRLGIASPMDGRRARRTVTGEAGSAHETRRDGAGGTRRDEPRLAVAGRQAGKLAGWRADWLAGAAPAGRPKFVPRAGPGCRARAQAHPRPGWGKLVMADPLPAGEATILGARGALRLVAHPQNTNNAKWIFGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWM6</accession>
    <name>A0A6A6NWM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ribose-phosphate pyrophosphokinase 1</fullName>
            <ecNumber evidence="4">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphoribosyl pyrophosphate synthase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_323312</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="4"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWM6"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000017">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000043">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF57">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="19" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="18">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="237"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="372"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00077829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2456195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="595" mass="62134" checksum="97E9F88470395637" modified="2020-06-17" version="1">MRQTEIFSGSSHPDLVDNICERLGQKPGKATLKKFSNGETCVEIHTSMRDQDVFIVQSGSSKINDNVMELLIMISACKGGSAKSITAVMPYFPYSRQSKKKSHRGAITARMLANLLHVAGVNHVITIDLHASQMQGFFKCPVDNLIAEPLIARWIRLHVPNWRDAVVVSKNPGGTKRVTSLADALKLSFGIVTTDSRRRPDPGMSSSAFFGAVGIESEDPLATDPSVALLNGILDGATDEKDEGRGGGFGDGTIGSSGAGGGGAKSPTRSGTRSGHHSRGTSSLHRRVNGNSAVEVPSSPLVRSVTRPDSSAASSVPSSPPTGAAVGGSLVRVQTTPSAAHAADEPDADAQYTDERARDVITGRLIQGHIVDEDHPSPAFSAASGPSAAPSLRFRSQTATTAGTTGTTATTGGGGGGGSDDGDPDAPMPEHMMSSFVSTASSAMRGAGGRHALGGSVDAAATSEEEEEELRNPELETTVTLVGNVRDRPVFIVDDMIDKAGSWVAAAETVVKRGGATKVYCFATHGLFGGDCLREMNECECIDGIVVTNSFPVPREKALGCAKLVVIDVGGLLAEAIRRNHHGESISQLYMHSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWV3</accession>
    <name>A0A6A6NWV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_349208</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWV3"/>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="144"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="548" mass="59274" checksum="685B7D04D82159A4" modified="2020-06-17" version="1">MADVHTLRTVADLSIDHGPQSSSRETSAPAAAASTADPVAKLTPTSSTTPANMPPKKRATASKPAVTKKGIAKAKPAPKKRKADEVATRNSGTPASRTSKTPAGGCNTKKSASGTPAAASPGAGDAAVAEGNDTDVGSVDSSGDVFCVCRRPDNHTWMIGCDGGCEDWFHGKCVNIREEDGDLIDKYICPNCTAEGKGNTTWKPMCRRDGCRKPARLRKGNPSKYCTDECGEMFFTARLGLPMDPVPNGASAEGNKKKPMKKKVTAILDDAEDDYLGPLGGALRPPEVKALTAAIPDFEAFRRLGEGVPSPPPTALPAEEDFYVTILDAESRERLDQIAAKKDELRVRRALLKDHDRFVTMTRERAARTAEREGLKPKDMCGYDAQLQWSEAEFSAWRASPIGRAALKLGTLEGEDFKQLAEQIRREEYGSLPTLNRSNGANSDPDGMEVDRDGPRDDGSPFSATPPPLCMRKRCERHKNWQKLALTDVRFEIVDVADAMRALEAEEKEIRQRAVLKWRAMTGSANRVDRASFSSTVTNGGEVEVVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWW5</accession>
    <name>A0A6A6NWW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Endoglucanase EG-II</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_373076</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Endoglucanase (EG) that cleaves the internal beta-1,4-glucosidic bonds in cellulose. The degradation of cellulose involves an interplay between different cellulolytic enzymes. Hydrolysis starts with EGs, which cut internal glycosidic linkages to reduce the polymerization degree of the substrate and creates new chain ends for exocellobiohydrolases (CBHs). The CBH release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain. Finally, beta-1,4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWW5"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000124">
        <property type="entry name" value="Exported cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF5">
        <property type="entry name" value="CBM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="9 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-0873">Pyrrolidone carboxylic acid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025380028" description="Endoglucanase EG-II" evidence="14">
        <location>
            <begin position="16"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="15">
        <location>
            <begin position="74"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00059691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2455994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="363" mass="38958" checksum="2E2FEC06934C0722" modified="2020-06-17" version="1">MKSLIIFALAAGSAARPSHVRRSLHSSLAPPNGSSSAGKVQYGGVNIAGFDFGCVIEGACDLTDTFDIASDGNGVEQMDHFVQDLGLNVFRLPVGWQFLVNDQLGGQLDDTNAASYDALVQGCLDSGSELCIIDIHNYARWDGGIVGQGGPEDDDLVSLWSQLAEKYADEGKVVFGVMNEPHDIPDIETWAETVQKVVTAIREAGATSQMILLPGNDFTSAANFVDNGSGAALMQVTNPDGSTDGLIFDVHKYLDEDNSGTHTDCVTNNIDEAFSPLADWLRENSRMAFLSESGGGNTDSCLQYMCEQLDFLNDNSDVYLGWTGWSAGGFDQEYELVETPVQNGDSWEDAPLMTQCVAGKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWW6</accession>
    <name>A0A6A6NWW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bms1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_348262</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWW6"/>
    <dbReference type="OrthoDB" id="10260897at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000105">
        <property type="entry name" value="BMS1 ribosome biogenesis factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="12">
        <location>
            <begin position="9"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="348"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="570"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="645"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1009"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1056"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="578"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="645"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1059"/>
            <end position="1105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1124" mass="127946" checksum="617BB403996FFA93" modified="2020-06-17" version="1">MVDRLPEEAPPIVVGVVGPPGVGKTTLIKSLIRRYAKQTLSSPTGPLTVVTSKRRRLTFVECPSDSLASMMDVAKIVDIVLLMIDGNYGFEMETMEFLNVLAASGMPGNVFGILTHLDLFRKQETLRQQKKRLKHRFWSELYQGAKLFYLSGVVNGRYPDREILNLSRFLSVMKNTRPLVWRNSHPYCLADRFLDITPPTNIEEDPKCDRTIALYGYLRGTNFPAQGARVHVPGVGDLNVANIESLPDPCPTPFMHQAMTKATGKAVRRRLGEKQRVLFAPMSDVGGVLVDKDAVYIDVKTANFNGEGSGEEKGLGEQMVIGLQGERRLLGQADKGVRLFKGSEALEKEDELDDTVRNRGRSTQRQARVVEREGDEDAGEDEGFESGDDSDEIELEGDEVTSENYHIGRENGNGQRHALGDSMDKMAIREDFTFADSDSDLGSLSSAEDQDLEEDDDEDEDGALRWKEDLAENAMLLHGRNRAHRTTELARLMYNDTLTPQEVIRKWKGIASEEEEDAEEAEAFFKRAEHEDAASDEDEDHAIPNFDYDKLERKWADKHNLEALQQRFASANLLGEGGDGEGSDEDQSAFADEDEGDGEFEDLELRNEEDQEDALSLSEAEEAKGIEVEREKNARKKEELKLRFEEEDREGLANDKGAERRDGGHAESEPFGEDDWYDAQKAAIQKQLDINRTEFDQMDETSRVHVEGYRAGTYARIVLERVPYEFSVNFNPRFPIIIGGLTPTEDRFGFVQVRIKRHRWHKKILKTNDPLIFSLGWRRFQTMPLYSLSDSRTRNRMLKYTPEHMHCFGVFYGPLIAPNTGFCCVQSFSNKNPGFRIAATGVVLNVDESSEIVKKLKLTGHPYKIFKNTAFIKDMFSSSLEVAKFEGASIRTVSGIRGQIKKALVRPDGCFRATFEDKVLMSDIVFLRAWYPVKPHRFYNPVTNLLDWAASKSGEGAEGEEGGSGGGWQAMRLTGEVRQAEGIPTPKDKNSAYRRIERPERHFNPLRVPRKLQRELPFKSQPAVRRPQRKETYLQKRAVVVGGREERQARALMQRLAALRKDKADKRRAKQEERREPHRKKAKEDEDKRRQREKRERDEFWEREGKKRAHWNQAEGGRGGKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXB9</accession>
    <name>A0A6A6NXB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_56371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXB9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="117" mass="12984" checksum="B06085E0621E084D" modified="2020-06-17" version="1">MLTLPRSRTYPDSEQEEEVRQGFDPDKARLVNPPQEHNLNAPFAVGDDEEDEAGSSAAAAKSSPHLIDVGGEAEASEWQRRDYRGENEEPPPSAGPRYGSYVDEENPWGGREEEDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXS7</accession>
    <name>A0A6A6NXS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_347421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXS7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="61" mass="6870" checksum="01E3724B368A4C99" modified="2020-06-17" version="1">MLIIEDEMRLSGTGVVSLRQSREDGAKYACNGPTVHEVLPHVLPPSQKERRQLKVKNIQLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY07</accession>
    <name>A0A6A6NY07_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_54210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY07"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="22831" checksum="39425E0330CCC584" modified="2020-06-17" version="1">MGLTSITRYPRTKIRLKTAFVCGHYSRHFRQYFRISFYHFFSIMNKHVMIILLANRDSSLAFFIGDFLIPGRQGSKQVSRQTGKQPCHCKAHVAWTALNGPGLYVAHQGPGHVSAYLGSEWKGWRQPRSLLQSSHQRLAMLVVLNNIRSHPRALQRRSTQGAGLAACCPADAFAFANLPTTSGDSLSPGSGSLLLLPLPQSARLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY47</accession>
    <name>A0A6A6NY47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eisosome protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY47"/>
    <dbReference type="OrthoDB" id="4070583at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024527">
        <property type="entry name" value="Eisosome1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28298">
        <property type="entry name" value="EISOSOME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28298:SF1">
        <property type="entry name" value="EISOSOME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12757">
        <property type="entry name" value="Eisosome1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="774"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="825"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="93698" checksum="B1856DE2433EBEF3" modified="2020-06-17" version="1">MTAQVAAQAAAPLRQGAGQMAHPACPGPAAHEHSGRLREQASHASHAALQQPEPGPAGAEPGRAGGSDPRLSSAGAAASLKHAQPHDLPGYPIVGIDAQSSAGAAASLANASQRNIEPWRPTTSDSAGKAAMLAGDYKAAPLWRPEASDAGSKAAQLAAANRDSHKTEPWAPDASTTANSHSAADIAMRPKSRTKPPQPDATSDETHRRAMMAATGAFSGRKRAESTPTPHVPTYPDAANHAQNALKAATHAHRPSPSAADETKSAKDAPISSSPALEAARIQHIGTNLPREMYTDSPPVTPEVEEKRRQDALRASAISMAKKMYDVQRHHLDGAASDHATAAARAGGQAPVPSHEDDVKTQAMQYLTVQDAAQRLAAERLSKIKTEDESNAFRSYYGYQSGPRSRLSLRRGGRRRASSEGSNLEPTADSDDDEARSRRIRSQMTAFNEQLAAVDTDKRKRDREALLAAAQRKVRTSMHDMDQKVYDETGKPSAALIEEWETKARAKAAANSEQRMANFGRVNVGGGKFLDQTDVDAVASARIQPTLDEINEKTEAQRARDEEIRLDQEQKKREAQVQKQREADLKAEQKRIKGEEKQAEKIRKQEEKNAAKAEKSADKARKAEEKRHQKEEKQKSHEEAKDEASNNPEAMATRGSSDAAVEDATASSGSSSSSSDDRETETAEPAASSSAAEAPQGHEASDALETEKSKSGRAPPTPGAEEEPTSPAFPSAKGEGGRFKSFFHKFKRRPRATSASEEQGNTENSRSFLGGHTLTGSRSSRPTSTGRDVASPTRGDTSRAHSGSISSLSSDEADTRGRGNNKTNGDAVSGSAVSAVSGPEESEEARDTVDDSLAPPPPAFSSRVSNGSPVRETRFQENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYS7</accession>
    <name>A0A6A6NYS7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydroorotase</fullName>
            <ecNumber evidence="4">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_386295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="4"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYS7"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000041">
        <property type="entry name" value="Dihydroorotase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="80"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="365" mass="39688" checksum="D71FFC1EE216C525" modified="2020-06-17" version="1">MALDAFRDCELPATADFHVHLRDGETMETVVPTIRRGGVNTVYVMPNLLPPITTVPHALSYLASLQRLEPNVTFLMTLYLHPTLTPGTIAEAARAGIAGVKAYPAGLTTNSAAGVVDYATFDAVFAAMEAHDLVLNLHGEAPSSPANGVSVLNAEEAFLPTLAELHAKFPRLRIVLEHCTSKAAVEAVRSIGSDRVRATITAHHLWLTVDDWAGDPFAFCKPVAKSAEDRQALIRAVVDGSGKFFLGTDSAPHPVQAKTGGTDRKGKIAAGVFTQPYATQLVVGALEKACEEGILKAEDVTKEVLENFMSGYGRYFYRVPNDKKEKIVLRKRDERVVDVLTSKSGRVEIVPFRRGENTWSVEWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYW8</accession>
    <name>A0A6A6NYW8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside 2-deoxyribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_364449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYW8"/>
    <dbReference type="OrthoDB" id="2893324at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039470">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15891">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19026" checksum="EC2F77059ED9C365" modified="2020-06-17" version="1">MSASLNIAPANGGERKCHVCLPTAPPVIKGKSIFLAGSIDMGMAVNWQTAITSKLAHLPVTILNPRRDDWTWDWVQDISNTVFRDQVEWELDCQDRADVIAMYFDKNGKAPISLLELGLYAASGKMVVCCPEGFWRRGNVQIVCKKYGIKLVDTIDDLVECVVGKLGQVSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYX2</accession>
    <name>A0A6A6NYX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Trimethyllysine dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Epsilon-trimethyllysine 2-oxoglutarate dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">TML hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">TML-alpha-ketoglutarate dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_286886</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:14181"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58100"/>
            <dbReference type="ChEBI" id="CHEBI:141499"/>
            <dbReference type="EC" id="1.14.11.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; carnitine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.8" evidence="5"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYX2"/>
    <dbReference type="OrthoDB" id="408743at2759"/>
    <dbReference type="UniPathway" id="UPA00118"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050353">
        <property type="term" value="F:trimethyllysine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2020.30:FF:000002">
        <property type="entry name" value="Putative gamma-butyrobetaine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000001">
        <property type="entry name" value="Trimethyllysine dioxygenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012776">
        <property type="entry name" value="Trimethyllysine_dOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02410">
        <property type="entry name" value="carnitine_TMLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF51">
        <property type="entry name" value="TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="18">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="17">
        <location>
            <begin position="106"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00071191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2456788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="371" mass="42410" checksum="0B20D1283D163FF6" modified="2020-06-17" version="1">MISIPSLQCSRPNLWLRDHCQCSSCVHEVTKQRLLDTFEIPRDITMQSLSETQEGFNVKCWWSDGHDSYYPKNWLNKFARGDSSRERQGINKASLWTSSIAESLPKVYFKDVMDTDQGVGQWLLNLRIYGFCFVEGCPPTPQDTERLLKRIAFIRQTHYGGFWDFTSDLASKDTAYTQISLEAHTDTTYFSDPAGLQLFHLLSHTHGSGGASLLVDGFKAAQTLKQEDPKAYDMLSTIRLYSHASGNEDTSLQPYQSFPVLNHDVGTGELIQVRWNNSDRAAIDAPFSEVQNWYNAAEKWVQILRDPSMEYWEQLKPGMPLIFDNWRVLHGRSSFTGKRRLCGGYINRDDYISRFKMTNLGRAAVLESVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZA7</accession>
    <name>A0A6A6NZA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_363965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZA7"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23811">
        <property type="entry name" value="UBCc_ScCDC34-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000051">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 R2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="189"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="201"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="249" mass="27764" checksum="65FC71435E1B33C1" modified="2020-06-17" version="1">MAERILMNEYKMLAKEPWTNIEVPAAAGPLVAFGKIEANLVEDNIFEWSVALIPTNKDSFYQGGYYKAIMTFPKNYPYSPPDFKFLRPLYHPNVYPDGRLCISILHAPGEDEMSGELAAERWSPAQRVESVLISILSLLDDAEVGSPANVDAGVLLRKDRDAYRARVAADVETSKQDIPLGFVMPEADAQFKPGNAKGNNDDDFNMAWDDSDADEDLDFGGSDSDVDFEADDMDEDDVMQETDSEEDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZL7</accession>
    <name>A0A6A6NZL7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZL7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="17446" checksum="24CE1EBB55E55F58" modified="2020-06-17" version="1">MDEMEVPELDHPVQTSGSSRSGRSRASQRKLVAAVVRFQGRPAQFDLENRSEPIWQQAVGGEAAEAVLDQIRQLARCSNPERRRRAVEMGWARGLEGLRGAVRRRSREAIWAGGGRAPRASQRRQTCDGGRGGGRRVRTIEQYTRRRQGGRRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P078</accession>
    <name>A0A6A6P078_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_285969</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P078"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10380:FF:000007">
        <property type="entry name" value="Malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="11">
        <location>
            <begin position="127"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="10">
        <location>
            <begin position="314"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="651" mass="71345" checksum="17DE86EC8536F9B3" modified="2020-06-17" version="1">MATLTNGTGSHAPSSTRQLSTTYVQDFPQARWKVPLVGEARQAPPPQPPSGPRKIEGVFPSSTRPTNACRSGDFDTSYPVEVRKYLGTYGMIPPAIDNYEAQSERCLKLLSMKQTPLEKFQYLTHLRATNVHLFYRLLADNVKELCPLIYTPTVGEACLKWHEIWTQPEGMYLSWSDKGNLYNVLKNWPHNVEITVVTDGSRILGLGDLGVNGMGIPVGKLALYTACAGIRPDATLPLTLDLGTNNKALLEDPLYMGSRRPKVTADEEREFLDELMEALTRRWPGIVIQYEDFKNPFPSLERYQHTYTMFNDDIQGTGAVVLAGFINAVRHSGVPVQDHKAVFLGAGSAGVGVAKQIVEFFVKEGLSEDEARRKFWLVDSNGLVTNDRGDKLAEHKIYFSRDDNGGKQIQSLSRLIEYVRPTILMGLSTIGGAFNKDILQRMARINERPIIFPLSNPSSKSECTFEDAVRHTKGKCLFASGSPFPAEEWDGKVMTPGQGNNMYVFPGIGLGAILSKSVNVTQSMIYASAEALSTALTPAERAADWLYPDIRRIRDVSVTVTAGVIRAAQAAAVDREPALRALSDQDLDAYVRRRMYDPFAEPRNRADELAAGLGRVALNGAGPNGAAEIVGTGRGGLALGGGELNGVRGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P082</accession>
    <name>A0A6A6P082_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA-like thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P082"/>
    <dbReference type="OrthoDB" id="1930760at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03024">
        <property type="entry name" value="DsbA_FrnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887:SF41">
        <property type="entry name" value="THIOREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="6"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="218" mass="24644" checksum="E5EA140993F86598" modified="2020-06-17" version="1">MTKFDIRIVSDVVCPWCYVGKKRLEKGIELFREAHPDSNDTFTTTWYPFYLNPDAPITGIDKKEMYDNKFGPERTRMMFARLSAIGEAEGINFKFGGRTGNTRNAHRLVQLGKTKGPDVQTKIVEALFEAYFENEKDITDEETLVSAGVKAGIEESEVKDWLKSGKGGKDVDSEVTEANSNMITGVPHFTLQDQYEVEGAQDPQAFTRLFELIKARNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P185</accession>
    <name>A0A6A6P185_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_16154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P185"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="26143" checksum="B5E15FB5C930A31A" modified="2020-06-17" version="1">MRIWRANRMLGWSFERDEKSASGRSAQRDGMPDLRRVTEALASTYRQTHRRARLRLRHVDIQYVDETPWARPVQASSGRRSERNETRAAVGPAAKASPDAHHVLGLTALGARPARPNPRPRPLRCSAPHPLLASAFGQRPLTHLALPSRCLPATSARPTTAGTAGALCRPSKPPSASRRVRLLVRAASPPAFTPKYRLVASGELHSLPAVPGPRNGRCVHLVCSHELYGYVHSFSFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1E8</accession>
    <name>A0A6A6P1E8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7820 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_342983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1E8"/>
    <dbReference type="OrthoDB" id="5384459at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056722">
        <property type="entry name" value="DUF7820"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42078">
        <property type="entry name" value="GLUCAN 1, 4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42078:SF1">
        <property type="entry name" value="GLUCAN 1, 4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25130">
        <property type="entry name" value="DUF7820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7820" evidence="3">
        <location>
            <begin position="276"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="626" mass="67934" checksum="40DC5FBAFD54EAA9" modified="2020-06-17" version="1">MTAHPNHPHNTASLRRSTSSASSFATTNRSQSPFQAASHPYGMYPQGTGVARSSSVVTSSTIRAPQRPLSGHHGPAHPYGLYPQNVFEDPDEEMANRPQPIPVGFPGHTGGFHRQIGPDGEEQDIIGPDGHTEQLPPYTRFPDEGHAKTAFTPLTVTTSNVDNGAETTNSNDTLVPNGGAAVTSPHRVSSTDVPFTNVSIDNGSSDMSEKKWKEKTWREKRKTKVLFGKISFCTVLVVVSVVVIIAIVVGAVIGAFFTKNKITDDSPSATVTVVSTASMFDASVLSVTPTDLPALPTGVWNLPFESPEESQYDCIADADAIAAWSCKIEDQPPAKIRVIGGQTNSLSGISISPMDSSSNAISYGPQIPDLFVQDLVLVSDLDDTQRGPAWHFQTTYDKIVVLRQEDFTAGLDRADKRQLIEVDLDDAFGSRAQVVAGERPWVCIWNSTFVEGFVFVTQNSSAVARSSALEASASTTSSSLSSTSTFPSFTTSTFADTSAPDPTTGPSGPRYQDDDSDDDDDQTWPGLMPFMPRDAIPTDTVIDLFPRVVKVEERRIPGNPNQPYCQEMQLLDDQTLAPVHDENEEPIIYNIPEVGASDEYTDPSDRMGRRKRTESDTNCHCQWVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1E9</accession>
    <name>A0A6A6P1E9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_38266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1E9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="235" mass="25084" checksum="8EA74E47B0FCBAD9" modified="2020-06-17" version="1">MADPPPAYTSTYPNHIHSDHMSQLAPGQSQPASRQSQPALGQPQPASGQPQPASGQPQPAPGKPQPASGQPLPASGQSQPESGQPNAQPQSNFLREPSTQPLPITRHRRTAFAQVSRLLGLMFGSPVNPVDVFSWVVVIPVISVILTLAVLDAKTDVIRLPSFVRLVGRGISVGFMELVSTFIVVVVFLSVYYLTSLESGQNVLSSFRSFVSPLTLRIVTVTIAYVVSVAIFGHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1S2</accession>
    <name>A0A6A6P1S2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_344569</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1S2"/>
    <dbReference type="OrthoDB" id="5295771at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="410" mass="44399" checksum="AE2B9F8B81C3C001" modified="2020-06-17" version="1">MPPPLSARAPHLQLCVSCRSFPHRCNSRPSLSIAVGAPVTRRFIQIQATPASSQPEFNNGGGERDAMEERVPPVGSPDARFEVVGSPSSLLSVSLSASQNLFTRRGTLASVSGKPENVTSTLSVLSPLRRSPLGVPFLYQKISSTTPLNLLVSSTTPNSTFVVIHLDGRIDWIVAQRNGLIAWTGHSLAVRPKVNMKMSLAHWGNTQITGRGLVALEGKGQIYQVVVRAGEEYIVHPSHVLAYTVTPSLPLPYRFRSLRLQIPSFSLGALVPDTKFFRAMSGTQTWRNIVRATHTLRTWLRRTIWGDRLFLHFRGPCTLLLHSRPGGAARALRESMSPSDINAIADSPAGEVHEAVKLDLKNHAGTGASGTVGSAGAGKEVKKPTEKVSYATVEKDGRVKWEESGDKVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P216</accession>
    <name>A0A6A6P216_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA repair protein rad9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_385522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the rad9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P216"/>
    <dbReference type="OrthoDB" id="60092at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026584">
        <property type="entry name" value="Rad9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009303">
        <property type="entry name" value="Cell_cycle_RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="393"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="436" mass="48859" checksum="3204EE46862BFD51" modified="2020-06-17" version="1">MVNLDFVLSPEAAVRVHDALACLAKFNEYVFVEARADKLSLTALNPSKSAYASFSLDRRKFFLAYDFSRGQGREPDGRFSCSIANKALASVFNKRRLSDGRGRETAIERCEVSVLDNPKASECRLVVKMVCEQGVVKTYKLTYESAEVVHALFDKNAAKNRWTARSSMLQEIIEYFGPRTEQLDLYYAEGRVTFTSFVEKITNGKEILKQPLQTSVSVEKEDFDSFDAEDKVHIITSVKDFKAVVVHASTMRATISTYYSNPTKPLQFSYGDDAMKCEFTLMTHGDFRANPSVDASHTVTNRSISTTQSNAQVQVNQRRSFSEIEPRTVQPARQPRRRKVPGSAPRPAETSQAQPHHEESLFVTQDEDDHRWDPVDTGHAGDYEDVLGWDASGVDTLSHPATFRDSGTASKRPAQDDLEGLPPTQRLSQVRGGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P259</accession>
    <name>A0A6A6P259_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_213243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P259"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025448390" evidence="2">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="10883" checksum="46AD0F90D14952ED" modified="2020-06-17" version="1">MSWLTSHLLFLSPAQECSCKMPSGNMIPEHQERSIPPSGTGGASSSGGTGGGSSSGGTGGGSSSGGTGGGSSSGGTGGGSSSGGTDGGSSGGDRGICPRCHRRTCPGGNGRDCSGGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2B9</accession>
    <name>A0A6A6P2B9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 alkane hydroxylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_285634</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2B9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF5">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="520" mass="59281" checksum="6B5C8E6BAC36F3FB" modified="2020-06-17" version="1">MLDSILSSLTLTRVLVFLVAWAAISKVVAVFLTARKVRQLGHQAAIRRTWLPFSIDIIAEVIYYALNNRNYEFWCDMFRRYGNPAAPHTVEAGELADRTILTCDPENIKAILATQFADYGKGEEFNREWKAFLGDSIFTTDGQKWHESRTLIRPQFIKGRVSDLATFERHIAPLTELFGGAGQTVNVAELFLRYTLDAATDFLFGRSVESLMNPQAQFAHAFTVVQHVQSMIARAGPFTFLIPRGEFNKQLRVINEFVHPFIEQALLLSPQELEEKTKSDEGYTFLHALASYTRDRTVLRDQLVAVLLAARDTTAGTLSWAFYELSRQPHIVSKLREEILRRVGKTKLPTYDDLKEMKYLQHILNETLRLYPAVPFNVRVSLKDTTLPRGGGPNGDLPIGVFEGTQVGYSPLVMQRHPDMYPPESSGFPPVEKFVPERWDHWTPKTWTYIPFNGGPRICIGQQFALTEMAYTVVRVFQRFASVESRMPGQEPGLNTDIVLQPTRGVRVAFWEDKNNEGQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3D3</accession>
    <name>A0A6A6P3D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine carboxypeptidase S28-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_385429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3D3"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000251">
        <property type="entry name" value="Extracelular serine carboxypeptidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025483637" evidence="6">
        <location>
            <begin position="24"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="556" mass="61529" checksum="6C53FD4C2CBD0851" modified="2020-06-17" version="1">MTSQRLCAVIGLLALWLAQLAVARTAVTPVKELRQRPRASPADDDEPDLESLYPAHNLSVPIDHFHNSTLYAPHSNGTFPLRYWYSAAHYAPGGPVIVLCSGETSGVNRLPFLYKGIVYQLAKATGGLGVILEHRYYGTSFPVDDLTTESLRFLTTEQALADTDYFARNVVFEDVDADLSPESAPWIMYGGSYAGAFVAFLRVLYPGTFWGAISSSGVTEAIYDYWQYFEPIRIHGPRACVDTTQAFVRVIDGILLRCPSDADLTARLKETFLLPNVTYDDDFANVLSGGITGWQGRNWDPEVNDPSFGYYCDNITTGELLYPDTEGLRDSVAELIGASGGAAGAAHEDDSSLTDRMLNWIGYVNATAVAPCAADSGSTQNQCFTNRNATYYAQTDLAQTWRAWAYQYCTQWGYLQTGSGAPAHIDPLVSRTIDLEYTSLICRDAFDIWTSSDVQAINRYGGFDISYPRLAIVDGEADPWKEATPHATVARDRASTVEEPFLLIEGAVHHWDENGLLPNETTADLPPQPVADTQATERDFVRAWVAEWYMRKDRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3E7</accession>
    <name>A0A6A6P3E7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Plus3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_378319</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3E7"/>
    <dbReference type="OrthoDB" id="166375at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115:SF8">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Plus3" evidence="6">
        <location>
            <begin position="263"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="475"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="61068" checksum="FE6015C70D823765" modified="2020-06-17" version="1">MSDSEFDEELLALAGEDEPGEEASPAPSQGRSPSPASSSASPKPLDTATSPPSARKLATTRSKSESEEGEASSPESLGSGAMSESESDSAPAPADSDDEIPDGGLYPVEGRFTSDKDRAEIMALPEIRREEILAERAAEVERKNQDLHLRRLLQAREKEEQRSLDKKKRKAGAADLDDSARKSTRAKTSKASDTLEAYKRQRERRGLERRGEATTDRLGREERGRRSSTRSRDDSDADAAGDSDVEWDPAAAATAKASKRDPSPDLRDFHRCHITRDGASRFGLWPEFEEVVQGCYVRICIGLDPQTKQQAYRMAQIKGFQSGEPYQLEDKTGIFFYDRYPIVTNGKLERAYPWQTCSNSKYGAEELAQFLVSLSEAGMARPTKRQLEARVDRINEFLSKSRSNDDINHRVKLRKKYQHLAALKRAANPPPPPGFSEHAALESRIEATNRANRLANQNDVNRALIEAKRQKKRAFAEAQRKREAERANGGGGAALDDLFDDPASGASRAATPKPAKRTLTPQTDNKGIPTVRKMVTEDEILQDMDLGIDIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3F2</accession>
    <name>A0A6A6P3F2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_411749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3F2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="483" mass="52156" checksum="B95DB2868B9CD175" modified="2020-06-17" version="1">MKQVPGMMTMGCGVAFTSKKSSCGGRDNVVQIGRRARAGSRIARAGGARHKRLKMRENMAGGCEGGRSENWAEGEQSAPSLDTGRSCRDASCLLVFCFWKPRREARAADQTGGTKVAIYYRKGKRAGGQRCAGGAAFGEQQRRGQARPGPHAAGPVFRVRIARERKVRSRYRVPGEHARLCARRCPVYRARRRLGAAGRCSWHERGKRGNGGVGGRGPLDLQSSIPSCAPRPAAARPALDLAVDKPAEGRRAGTGWYGCGPLGAAPRLTASTARRRPPDAQRHHRRARRRGGLRWSWAGPVWSGWWLRRAPARRWPVAVATARARGRRVAGAVLRSNQGPWDRSLDLDRVLDRALALVLVPVLAPFAVPPPRPRPVARCKATSLHRPMSRGSPGDARPTCVHWRAPPCSSRRVWPAGRPAPAAARICSPAPIGPAPQLPPAGSRAGVRRPAARTGHSAARLLPARRRRGSNLPRRAAGGGRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3N4</accession>
    <name>A0A6A6P3N4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_212916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3N4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="25510" checksum="A0B495FBF81C5C2E" modified="2020-06-17" version="1">MWGAPKMAKESCVCARSSVGAEMEEAHHQGRRQELLAGGGRWIPCGTVIGGPGPVSTIYILCFPPTRNWSIQHRARGLKMRPHVLRRTTVGQAFFAGAWAPGGPGPRQAAISRPTPPAPGAGCGLAPLTKASPASDPGSPALRRRDPWLRRRHTEHRSTAHSAALPASSRSSEITDCRFRIAIADRPRGTEYAERACSTVPLAPCPFRATAFPSRVGATITNHPSTVQPPFHALPWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P439</accession>
    <name>A0A6A6P439_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutathione synthase</fullName>
            <ecNumber evidence="3">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_257094</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="3"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P439"/>
    <dbReference type="OrthoDB" id="2020073at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="13">
        <location>
            <begin position="255"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="429"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="432"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="492"/>
            <end position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="553"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="559"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="63320" checksum="D5FFE5F8AB19E9BE" modified="2020-06-17" version="1" fragment="single">ESYPPTLPKSALATLVADIKDYQLTHGSLLKIVNPPPAFLSEEDEEDEDEQEIASIGAVLSEPIGVSIFPTLFPRHLFEQALELQQSFNELYARVAADSEWLKETLSELVEADEFVRLLWGLYEEVYGEDTREGTRKRRQRVQELSVGIWRSDYMLWQALGGTDAERGDETAATARKSLGIKQVEFNTIACSGGAHGNIAADMHHYLDTTGLNPASLALPGSTLPPNTTIEGIVATLAAAHAAYADQRARPDLETCILMLVQPYNYNVCDERPLEHALSQREGIPTFRVEFGGEFLALTEELDRNFDSNSADDDAEEAPPPPLLFTHPLTRRTYEVSVAYFRAGHEPRDYSETRPHHCTQPSSLRSRAIKCPTLGAHLAGSKRVQAALAAPGALGRWVSDIETRARLEETFVEIWGQEKMEEVVAATGMGKAEGKDAGDGGGDQRRGNGGGEGPRYVLKPSREGGGNNVYGDKVPTFLSAVGQEQWKKYVLMDLIKGPDKNVFGTRNMLVLSEQVYDGEVASELGVFGGCLWRNGKDVQIVRNEGIGWSFKTKGKHMNEMSVVKGYGCFDCPRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P494</accession>
    <name>A0A6A6P494_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_275382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P494"/>
    <dbReference type="OrthoDB" id="3535086at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="5892" checksum="6466AF5002705ADD" modified="2020-06-17" version="1" fragment="single">PPYNSATRHPVFFGSSLRQSPFPMGAALGHEVSPVAHGYIFHEGRPGTGSGGQTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4J5</accession>
    <name>A0A6A6P4J5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PQ loop repeat-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_339288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4J5"/>
    <dbReference type="OrthoDB" id="19344at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF11">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="39718" checksum="76946E8AA71C0219" modified="2020-06-17" version="1">MDVTPIPGASLFVAPPSKCDEFHRLNKVNFGVSIFILFGILVSYLPQHYRIIARRSSEGLSPYFVLLGTTSGTCAFFNILTLQGSRDAIACCAGAEGGIPAFACGAALMGIAQVGVQWACFFVIMLLFLIFYPRDTDIEQLPDRQPDSPSTMRTSLLTPTTSPAPTHPREPHAHPGAKPPAHPYRLAVLTVALSLTHLLILFLLTLFLYTLAPRALTPFANVLGLCASVLASIQYLPQIVTTFRLRAVHSLSIPMMCIQTPGSFVWAASLAARLGWAGWSAWLVYVVTGCLQGGLLVMGIMFEVRAWRKRKARVESWDADGEGIESYHSGGAGSEGGESEGEADVNERTPLVGSGGRVAKINGQRRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5C4</accession>
    <name>A0A6A6P5C4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_203470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5C4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025556245" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11120" checksum="5F80F70CA58E7D32" modified="2020-06-17" version="1">MVGRFKAHAKLFVLLGCILMTSSSDAKGPYNATLNITIFLWPALRPHHAAWHHPGRRKNVASPYGVLATGSPAGTMCICPSADSARLDGMEHVVHCSVAYSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5K0</accession>
    <name>A0A6A6P5K0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5K0"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36784" checksum="5A3B75221B58B30A" modified="2020-06-17" version="1">MTAQASPDFVLTPEQISHFMEHGYIHLKSCFTPEFADTVKEGLWDRLGMSPTDKKTWSQERINMPMHRTFDIATYAPAAWAAISQLVGGEDRVLSKQRVWNDSLIVNLGTPENEGKHMPPQALPGWHVDGDFFVHYLDSPEQALLVIPCFTKIVSGGGGTMIAPDAIPKVAKHLYEHPEGVSPRMTPRGENPNFVEEKGLDWFCSLAKTCNNFVEVTGDVGDVFLLHPLMLHSSSTNPLRMVRVITNPPVSIQDPFCFDRKDGNYSIVECATLKALGKDNLEGWAITGERQNLVPERVRIQEKMKRGEEERLEAMRSKLKTSPMVAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5P6</accession>
    <name>A0A6A6P5P6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_282834</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5P6"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF15">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="43"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="481" mass="51831" checksum="986D10F29976FCE9" modified="2020-06-17" version="1">MEGYPDLPAPPEFDESMPNGGDSLEMDVNAQYQAGLGFHYTYIIFCGFIVWLIIPGLGLLYGGLARRKSSLALLFQSLMVASVTTFQWMFWGYSLAYSRTANAFIGDLANFGLKDVGVAPSPGSSYVPEIVFCLYQLLFCACTVQILIGGSFERGRIVPSLIFAFIWATIVYCPIACWTWNGNGWLFNLPSLDFAGGGPVHIASGCGALAYALVLGKRKHKGERTHGKPHNTTLVFLGTVLIWFGWFGFNGGSALNGSMRAMWAAFNTNTAASMGVLGWVLVDYFKHGQKFSVVGACEGAIAGLVGITPAAGYVSLWLAAAIGFITAIVVCLCQNINQWLHIDEGMDVFKLHGIGGMVGSFLTGIFAQTWVSALDGGTIAEGALDGVGVQVGRQLADITAISSYSFVVSCIILLILKYIPGMNLRVSEEAEMIGLDVDQFFDEQIGDWTMFEENPIVSMSSPREQSLRSMEGKNAEAVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Z8</accession>
    <name>A0A6A6P5Z8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_190450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Z8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="287" mass="30670" checksum="D1D63193A565C50E" modified="2020-06-17" version="1">MYCVPSVEHAKGNVRPYVVVAKALHRSDPPSVIASEAVAFVALRQLRPSSLDSALSPPPSSSTYIVRFGRETWLGPSDPVLGKAIGASGEAAGPLPACSSVKVAAARRNQRDPSAGLQQAHPSPGSSRRLQDGVPAGRACDGDFATEYPETPVSTRRRRCSSRGYRGAWEGEAPSELTMRASSLARISTRDLRSDVCGRLVEEARAEATDEERDSPGAQQASHCAPSLWSPPGFPGLSSQTRSNTGSLFFPCLFLSRLHRDTECRHLTIPCYPARRIPGPVCSGHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P651</accession>
    <name>A0A6A6P651_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_338013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P651"/>
    <dbReference type="OrthoDB" id="2137750at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019626">
        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="10509" checksum="B280960B393A9280" modified="2020-06-17" version="1">MSDNPGSFANRPTEEVEEIAAQGGHASKLYANHVDPKGTYNPGNFANRPTEEVREAAAKGGAHSHGPTKSGEDVMMQGRNPDGTFQAGSEAAKAAGEIGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P672</accession>
    <name>A0A6A6P672_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_337973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P672"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="18517" checksum="24323CD8B29395CD" modified="2020-06-17" version="1">MLRRAFKSHPLGYLLHSEIIRTPSVHDERINNWQERGRVGGGRHSVVRAARNCISGEIGVAKITMWDCGSVTPGASNRNIIPSWYTKGLFRGSAGSAVTNEIAVLRKLEDLRCVSTVYRSQPFIEFSASFKRDHILLPAIIAFRPPCEAARLQDTQRIWGAPSSCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6B7</accession>
    <name>A0A6A6P6B7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_408661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6B7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="19600" checksum="485FCCA41094F7CE" modified="2020-06-17" version="1">MPIGREGRSTGTFVTVRSAAAAHATGRAACSRTCQNWRGGRSAWEPFVGNGVLSRIRGTAFSNSTYGLQPSDGRGIVGRAGRVTGLSRAGRRGLGRSTTFGTLQRPPLDQAAAGQGGGRRLRRTTQLCGVRVSGAKMRSPSGADREGSVFWVVLQGGMQRRFVRGSIDEEFGGGRPHGLAGPTSDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6J4</accession>
    <name>A0A6A6P6J4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_408994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6J4"/>
    <dbReference type="OrthoDB" id="5598057at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13311">
        <property type="entry name" value="PH_Slm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046868">
        <property type="entry name" value="BAR_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046869">
        <property type="entry name" value="SLM1/RGC1-like_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043453">
        <property type="entry name" value="Slm1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941:SF16">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20400">
        <property type="entry name" value="BAR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20399">
        <property type="entry name" value="PH_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="429"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="547"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="641"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="771"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="778"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="823"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="852"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="910" mass="98257" checksum="5016B9F82806E93F" modified="2020-06-17" version="1">MSMNQHIYGSVPPPNPAQVNRGYGMSSAPDGQPSGTDFADTPGNPIDSSPLSQSLQQPNAMAHHGRFEEDFDASQRGSSLVADGDAAGLQRSASRASATSLGGATPKRSNTLTKKASVSRKSSLKRSGSRKSLRAGSIKGVSLSDGVSEDYNSVFYTPVPTSGSPTDILVSRFQAWRKLLKDLIAYFREVQASYEHRAKSLLKVSNVINNTNAPPLFLVEGGLNDANRILRDYHKQVVVESNKARDIESEVIAQLSGLRSDLGQKIKEIKSLSGDFKNSVDKEKESSRKSVAALEDALQAIDTDPTSVVGKGDPFVVRLGVDRQIERQIDEENYLHRAYLNLEGSGRELESIVVGEIQKAYNALATILKREADETLQTVDRLRNGPIAMSKDYEWSEFVEHDPHFVNPSAPLRRVEDIEYPGKHHPAAAEVRAGMLERKSKYLKSYTPGWYVLSPTHLHEFKSADRIYSQPPVMSLYLPEQKLGSHSQPGSSSHKFILKGRQTGSMHRGHSWVFRAESYDTMLAWYEDIKSLTEKTGEERNAYVRRHVRSASRGSQLSTASDEVGLENDEADEVPYSGNASLSQGAAGGQVQPQPYHEQRPSPGGRFPSDLQVNRHLQAPLSPSSGSSAAEVENVDRDLSTIAGGPQQNQAQHYDQNNHPPTSQYPPPPAANNTPYDYAGYQQPTHEPYDPYSQQHPVPPPHAYPGQSHYGAPAPPDALPSESSRAAPYPEEPLPQQQPQVYLSENSKPAEPDLVRHNSLYGDWMAPVAAGAAGGAAGATTAAASKSKEPQPTAEQPAAAPQAIVEQPHQQQPEAAPMPVPVPEASTSESAPTSTTAAALSPSAVQNEPAVGSTSVTSGPTSLGSDTPMSVPSLGGKDGDVLPKTVSRQNTDVSVSDLEVPGRYPKSIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P758</accession>
    <name>A0A6A6P758_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase I-specific transcription initiation factor RRN3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_281744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRN3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P758"/>
    <dbReference type="OrthoDB" id="26970at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001042">
        <property type="term" value="F:RNA polymerase I core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007991">
        <property type="entry name" value="RNA_pol_I_trans_ini_fac_RRN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790:SF0">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IA RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05327">
        <property type="entry name" value="RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="652"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="690" mass="77683" checksum="2F7292943021BEFB" modified="2020-06-17" version="1">MTSNGGNRVSLKRKLGDTIAANNNNSNNDDDDEPEPSSSRADGRRPGKRARVAFDPAVEVRIMEPWSSEKSVELVRHEVRRGLERRAAGDASGTDGIKALFEARPAGGEDGEEAPSSALLRRYVNALTGNVSLVGKNCAGLVHAVLESEWVGRDEAFVAAYTRFLGGLISAHNGYLRSVMNMLVDKFIELPASSGRLVDHEVVDRAEMQARVHRVVQYVLRLFPSASRTLSPLLAEMFPFSAESTKVHIQYVQSLLKVADYAPELKHQILALMIERVLKIDVQIQVDMEDLDEDMEAAVQEVLDRADDEEASDDDYDSDDGSVASDEEGVESEEKRMKNLKRSLATMDSILDLLFQKYDPEFTKVPSRDADTAFSHLLAQFQNTILPTYRSRHTQFLLFRFTQKSRQYMDQFISTCLNLSFDKLRPPVLRLASSAYLASFVARGVHVNGDIVRDLFNAIGRHLSDFRAAQQSKCTGPDAVRFASYYMLVQAVLYIFCFRWRDLLDDHALEDDITDQDVDDMLLEGRDLPWAFGVKEVLRTNIYSPFNPLKVCSPAIVQQFARIAHHLRFLYVFPLLETNKRLRLSRSVASLAGGPAAAATQFGGDFTRRESALAYKTGDEAFQLDAYFPFDPYQLPRSKRWVESDFVAWKAVPGMEDEDEDEEDSSDEEDEGDEMEEDEVRTVKTATDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7M4</accession>
    <name>A0A6A6P7M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Carbamoyl phosphate synthase arginine-specific large chain, mitochondrial</fullName>
            <ecNumber evidence="14">6.3.4.16</ecNumber>
            <ecNumber evidence="5">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">BDY21DRAFT_281708</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CarB family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="14"/>
    <dbReference type="EC" id="6.3.5.5" evidence="5"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7M4"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000004">
        <property type="entry name" value="Carbamoyl-phosphate synthase (glutamine-hydrolyzing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000015">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="23">
        <location>
            <begin position="243"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="23">
        <location>
            <begin position="780"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="24">
        <location>
            <begin position="1045"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00068891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAF2459874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1202" mass="132034" checksum="9C05C530F1FD2226" modified="2020-06-17" version="1">MAFSGYVARRAAASASPGLLLRQSGSSCRQAAAARPLPPAATRLFTTAAPLPLRPHKQQRQKKNPVQTQRGFASSARRARIQSQEAPNAQAYLDSGAIAGGRDLVDVKKVLVIGSGGLSIGQAGEFDYSVRLLTSRCHLGSQALKALKEAGVQSLLINPNIATIQTSHVLADQIYYLPVTPEYVTYVIERERPDGIFLSFGGQTALNLGVRMDKMGIFDRYGVKVLGTSIKTLETSEDRDLFATALKEIDIPIAESIAVSSVDEALKAAEDVGYPIIVRAAYALGGLGSGFANNPDELRNLSARSLTLSPQILVEKSLKGWKEAEYEVVRDASDNCITVCNMENFDPLGVHTGDSIVVSPSQTFSDEEYHMLRSASIKIVRHLGVVGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYTAAKIGLGHTLPELPNAVTKTTTANFEPSLDYVVVKMPRWDLSKFQNVKRDIGSSMKSVGEVMAIGRTFEEAFQKACRQVDPKFLGFQGDKFEDLDNVLQNPTDRRWLAVGQAMFNEGYSVDKVHELSKIDKWFLYKLQNIVDLTRELEDIGSLFGLKEEILMRAKKMGFSDKQIAKAVNSTEDEVRARRKGYGITPFVKKIDTLAAEFPADTNYLYTTYNASSHDVTFDDHGVMVLGSGVYRIGSSVEFDWCAVNATMSLSKLGKKTVMVNYNPETYSTDFDVADKLYFEELSYERVMDIYELEAAGGVVVSVGGQLPQNIALKLQETGKAKVLGTDPNDIDKAEDRHKFSQILDSIGVDQPAWKELNTVEEAEEFARSVGYPVLVRPSYVLSGAAMTVIHSEEQLKEKLLAASDVSPDHPVVITQFIDSAMEIDVDAVASGGKVLVHAVSEHVENAGVHSGDATLVLPPVTLDQRVQDRCKEIADKVAKAWRITGPFNMQIIKADDPEGGEPKLKVIECNLRASRSFPFASKVLGTNFIDVATRALVGREVPEPVDLMKVERDYVATKVPQFSWTRLAGADPYLGVEMSSTGEMACFGKDLVDAYWTSVQSMMNFRVPQPGEGLLFGGDVAKPELAAIVNYLAPMGYKLYAANDEVKHHLESGAKPRDKDGNEVEVEVEVIEFPKEDKRALREVFEKYDIRGVFNLARARASSLVDEDYVMRRNAVDFGVPLFMEPKTAVLFAQCMSEKLPVKEGIPSEVRSWSEFVGGRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P804</accession>
    <name>A0A6A6P804_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_184494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P804"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="103" mass="11452" checksum="6B8438214DB421AB" modified="2020-06-17" version="1">MQAGKLPSPAGTLVMTTMALASSVVLTARRFYFDGGWEKRVSSGIFPHFGFAFSMRLMLLLFRLGPRYGAMRLATMQCVRFSDIVHDVACCCPRTQPSCLHMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P846</accession>
    <name>A0A6A6P846_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_409271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P846"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="267" mass="27577" checksum="CBB27E41DA3F6F29" modified="2020-06-17" version="1">MWAAQAGAKWQPHRAGGSHTSAVLDPRPLPPRPRLRGGGVVGYGGGLRNDAARGRATGTGPQDGRPRSLLRTAPYPALQAPADVPVRALAYQPATESIISPARPAALGRVRVRAHSCSEARFSAERGRCSSRRQACRAGRRRNLEGPNARGEKGSPSGAASERRILKRHNSAGPGPALGATHASAATTGGLGPAATAAQGPSRPAAAAARTLSSLLLRATRAPRCAPGFWAPAGPPPGCGPEMGWWIAPPLTSLGDRPESTLWQGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P898</accession>
    <name>A0A6A6P898_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_369896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P898"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06869">
        <property type="entry name" value="PX_UP2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="231"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="841"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="888"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="428"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="845"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="888"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="916"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="953" mass="108463" checksum="4A74FDC2B7DCB2A2" modified="2020-06-17" version="1">MAGEQQIPTVAINGKPDVQPNDDSAKAADRGAEKDAHEEESRALRPSMTRSTASSVSIPPPGSVLTGKQEHYLKRELISKQSRWEISELSSPTALQRFGAPFRSDAGEVSPKDSELPILRYIFVHHVRNFPFLDQAREKEFWQDKLQVFLESFANKHISSSEDRLEETKRRKLAIKAEKLVELMMVSGLPTASGYEERIRFSEMEVVDRGANEQGLVVNIPQGHEINGWDVNVAGVRTTSVKRHMRYHQHAEFIIRAKQSGEEEVFVGRRYRDFFNLHKRLRLELPGKVLPPLPRKNKSNTTFASGDDDTDSISSVSTQDTGFLDPSDASGGGLRTYLPGFNNHKRNSSASSVRSGRSGRRSSEGIPREPMVLYREEQRVSLRAFLRTILHNEHIAQSVAMKEFLTGNPVSLNEEEIEDIDRRKDMDEKRVEEQKQFYEIARKRAQELDVHMEKFRREIVESNGLSKLFQEIKVKNYISELQPEYQKFAEWLRIEVAATIYHLFLAEDNSPELFAQAKRIHSLVPYTVLKNVIRLANPAAVMGGVLDLFLAQPFGARSLLQRIFGMAIQDGIRSVQRSIDSLGTKVGDPVLCDKVKNYTQSNETVKVALRQEAEDEQVDLIVSILRTDLLEPELNEEQVGKVFNAYVAWNNAVENVDAEMRQGAEMFAHLKQMLKLCMRQRDKAMMLEMIEEPTTLQLFRDLFTIFYEPLVRVYKSANVYNSITDFAAFVDDTIRTVESAQRQDVSADPNQTVQAFIDLCARHEDNFYKFVHEVHIHDNGLFDQLMSWLEGILEFLRKGPRGGGKLDMNALFLGAMDSGQVDKEKAIQEINSLIKWQTARKKWHQDKTRQKMAAEGKDPMADMIPGLQSFQSSDFGLNQLDLEDLELDAEESSDGSELDEEEETDPIGAERKRRARQAEMLRRSAGEPVKPPVEEIHKLHDGFITMLRGVLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8A1</accession>
    <name>A0A6A6P8A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_159158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8A1"/>
    <dbReference type="OrthoDB" id="5142960at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="425" mass="46830" checksum="66DA08E5F72C233F" modified="2020-06-17" version="1">MESINNAILEKEREAWIACESKNYAEASRLFEDACVISEGLRGPDHDATLQILDGLALVLDKANRHKEAAECNQKILSARLKKPKQNDTLQTRSRLAQNMLNMEENAEAARLLEINLDALTKKPESEDLYWTRHELSRSYFRMKEYPKAADEERKALEVGEKVLGRRNHALVTCRHSLGNVLFLLGRMKAAKNIFSQNLELMNARAANGDSRFEWNIKETVKWIDRCDKSMAGPGKNQAQKAEARADGVRRNAEQVAKGWEQKKEGIEMNARPNQAGGPSKPVKNFGGQSASSDLLAPPGNRTQRSNSASAEDRVREGFKHVPARIGGSKTPPPPKSQGPNSPFRKSQEFQKPHEVARRNAGVGNKRGGAFSSRGNHQGTKRPGPDPAGDGKPGIPLPVGPAQDAKGSAGPPLFDARDAPERVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8F3</accession>
    <name>A0A6A6P8F3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_337743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8F3"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000577">
        <property type="entry name" value="Proline utilization protein PrnX, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="51714" checksum="16D2BFD9FF08911B" modified="2020-06-17" version="1">MSFTILSDDAVKSVLHALDKDDVLALQQTLADSLHVYSNDDDTNGCDSSYQLPRQSLRQKDGRTTLFMPACSNDNVGIKVVTLSAGDSSSAAGHSRGSSTPSSKDAPSLAQSLSQSLSSASMSSSPSPSSPADAPPDIEYNIKGRASIQYGASNNKTAATTPRGALTLFDSTGLMRALINAEEITAFRTALASTMLFKKRQNVHDVTIFGAGKQAYWHARLALILRGDDIHHLNIVNRSFDGAQRMIESLFRRDDGPVARHPIHQPKLAIITPHHPEYQRLLKQTLRQSAAIFCTVPSEEPLFPPAVLTSTEGRRRGRYISAVGSYKPHMVELHPDILRQAVAPDHGNHHHKHARQGGAVIVDSIEACMREAGEVIQAGLSGREVVELGELVMLKRDAEMRKRESEEQEGSGSGGKFLHHKRTKSQSYDDGLTDWLERGNVVYKSVGIGLMDIVVGAQLVDIADSRNIGVQIQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9I5</accession>
    <name>A0A6A6P9I5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9I5"/>
    <dbReference type="OrthoDB" id="4746261at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057394">
        <property type="entry name" value="PIGBOS1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23670">
        <property type="entry name" value="PIGBOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="72" mass="8124" checksum="0DBE376437BACE0F" modified="2020-06-17" version="1">MSMSRVSGKSLLPLAMVTVFGVVNGIYTFRPAFEHQHHDSVHVEQDRKLKIAEPESRNPNQSEPRHTEQSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9M1</accession>
    <name>A0A6A6P9M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-ketosteroid reductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_369567</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9M1"/>
    <dbReference type="OrthoDB" id="9989144at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000253">
        <property type="term" value="F:3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051593">
        <property type="entry name" value="Ergosterol_Biosynth_ERG27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647:SF1">
        <property type="entry name" value="3-KETO-STEROID REDUCTASE ERG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647">
        <property type="entry name" value="DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="456" mass="50758" checksum="9FC1540ADF52C0ED" modified="2020-06-17" version="1">MADGQSEKLYVLVTGANSGLGFSICCRLIDEFLQMRPQSQSLVLILTTRDREKADDTVHRLRQHLFKHCRRAERTIPGVSMLLQRRIHFESETLDLTSLISVQLLARRLLDTVPRLDALVLNAGIGGWTAINWPLAIYLTVTDLFDATTYPIYKIAKTGWLAKRQLPSKAGAEGAEFSSPVDEPRLGQIFCANVFGHYLLAHYLVPTLSRGAQSGTGGRIIWISSIEGGLASLLSRSDIMGLASKTPYESSKRLTDILALTYDLPSTAPWVDRFLAMPTRPPAQPNAKAGSDPSGSTSRPKVYVAHPGICFTAIMPIPWILQMCQLLVFYFVRLLGSVWHVVDSYSGATAPVWLILTPQTRLDEIERKGGKGKWGSGCDRWGRNKVLRSEVEHYGIGGIVGQEIPPESAGKHSKPLTEEDKGLFEEEGRECWKQMEEMRELWERKLEEALGERVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9U2</accession>
    <name>A0A6A6P9U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_280755</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9U2"/>
    <dbReference type="OrthoDB" id="10252502at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 12" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="471" mass="52290" checksum="9171DA041450A3BB" modified="2020-06-17" version="1">MSWLSASRSLDNPVRSLLAIWACWKTLLLAVVVVSPGPGYDTSTQILRLQDGAVEQYVHPSAGWLSTIGQHVALKLTRWDAIYFVRLAQRGYVHEQEWAFSWGFTRLINTIALNFPGGQAESLATHALIAATISHVSHAASVVVLYKLACHVTSQNTRNGVAFITAVLHVLSPAGIFLSAPYAEALFSLFNFSGMLFYVYSIPRPDSTNSRLLRRDINVLISGACFGLASFMRSNGLLSGLLFASDLFQTLPTLPRSLLSASGLRRQMSLALAGILTACGFVAPQWVAYREYCVAQLHGEESRIWCRSLFPSIYSFVQKHYWNVGFLRYWTAPNIPLFLIAYPTLYLMLSTSSQARAGWLVVDRRIPQKSSKTRDADRPETDRYLEKCLRELALPQLVLAITAVTNFHVQIISRIASGYPVWYFGVAAALVAEAQKSHGPQFFVRPKAIVRYLICYAVVQGGLFASFLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAM2</accession>
    <name>A0A6A6PAM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED19</name>
        <name evidence="11" type="ORF">BDY21DRAFT_136580</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAM2"/>
    <dbReference type="OrthoDB" id="2160599at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28270">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28270:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08633">
        <property type="entry name" value="Rox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="26186" checksum="BC5D08F06FAD4EA9" modified="2020-06-17" version="1">MSRPHPSQNLISLYGLDDVASSVARKDPKTGEKINRLRKSYENKVKELRIAGKNKATSTPGALLGIVDWPEEEWMNQKVFGKEVERGLQPSVLAKLDKAVQMAPGRLPDSEQAKWRAVVGTDDSSKAKATSGQQATAQNANKKLGKPAATASNRPSAAPSPAPAKALRPERTGTKRRYDESSFKGYGEGYADDDPLGESTGAEDEPRGAGGAKKKRKTKDYPAGSPLGINAGSSGYNPGIVSIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB80</accession>
    <name>A0A6A6PB80_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein ERB1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic ribosome biogenesis protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ERB1</name>
        <name evidence="10" type="ORF">BDY21DRAFT_334645</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat BOP1/ERB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB80"/>
    <dbReference type="OrthoDB" id="5571054at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000061">
        <property type="entry name" value="Ribosome biogenesis protein BOP1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03027">
        <property type="entry name" value="BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="9">
        <location>
            <begin position="185"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="452"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="784"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="554"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="809" mass="90791" checksum="D1F9066810F8D6D0" modified="2020-06-17" version="1">MDMATPNHTGQKRKVVSPEAPELTTQQEWEGHEELDADLEGILSQGEDEVSEEDVSSSEEESEIFGEEEEEGLGSEEVPSSEDEEEVLVRKDLGKLSSPIQASKSDDKTSIHANQRNGTWQDAKTNGVHGGNLEEENDKPNYTVTTDANGNPRYVYKDIEPVYDSDDSDAPTMTNTIGNIPLSFYDGYPHIGYDINGKKIMRPAKGEALDALLNSIELPKGWTGLTDPETGKPLELSREELEVLKKLTRNEVPEEGYDPYPDMVEYFTSKTEIMPLSAAPEPKRRFVPSKYEHKRIMKMVKAIREGRIKPYRPPEEQEDKEEDVFNYDVWENEAPRADHPMHIPAPKLPRPGFDLSYRPPREYLPNKAEREVWETADEEDRDKEYLPTEYDALRKVPGYSRFIKEIFERSLDLYLAPRVRRNKLNIDPESLLPNLPKPDELRPFPTTCAAVFRGHEGRVRSCSVDPNGIYLASGGDDGTVRVWELLTGRQLWMVRLTPGREKDGEAVDSVRWRPTKDTLILAAAAGEIVYFAIPLQLAPPDVAQRSHQVLDAGWGHGATNDSNIATGETKEQPGKWERPSAKLVDAGVLITVTVRSTVKVLTWHRRGDHIATVSPRGQSHAVAIHTLSSHKTQLPFRRLRGLPQTARFHPSKPIFFVATQQAVRAYDLAAQTLTNTLQPGARWISSLDVHPGGSNVLVGAYDRRLLWHDLDLSPRPYKTMRYHSKGVRAARFHQGGTLPLFADASDDGTVQVFHGSVVGDLLENATIVPLKVLRGHKVVKELGVMDLDWAPREPWCVSAGADGTCRLWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBB2</accession>
    <name>A0A6A6PBB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_81484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBB2"/>
    <dbReference type="OrthoDB" id="1932312at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="483" mass="51737" checksum="801A52A44179D474" modified="2020-06-17" version="1">MDSPGILVARFLKANGYDDTFAAFIKEAGLPASAGTISKNDVTIEQVLREKQMYDKALSYEKAGGGKDKGWHHPYPSVPMVLGNLPTSTNILHVSVENICPAGQSAAVPVLLATTADRKLHMLRPTSSPGGLLEVHRSLATLQDSPILSYATIGERYLINTSMSGKMVLYDCKGEAILDSRKDHLKYVVDVVAWQSKGCTWVATAGWDSKVLLYRVDPSTEKIRLGDPVARVVLPTIPESILFVRHPDNGSPVLVVARRDSSFLFYYRIPDLDGDSASVSELELLGRQNLAPHSNAWVAFTPAAMRLSPIDPLVVAVATSAVPHMKLIIVRLLLPPLEAVSTGATGAPLSTSSTLPASLPELADSPPLTQASQARAELALQDREEAAIILNCTTFAPQTPLSTPSLAWRPNGSGVWVNSDDGVIRGIEATSGKVMVKLEGHTPGSKVRCLWAGQVAVAGQAGGTQEWAVSGGFDQKLIVWRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBD6</accession>
    <name>A0A6A6PBD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_368550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBD6"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="23630" checksum="0FBE7A18C27A2657" modified="2020-06-17" version="1">MQDIKEAILFSHSCTEALKWMAFLFAGLLEGTWTHCAEEFHITSTPPARKVVFIRTSDNCRKSTDEFMHVVWRVQLKSGEVWAVDLTGAQAGIPMSCAPWHDYSRAYIQDILSDEYFGFCAIRRWRERLDTTCAVGDAANDLQQQMLVELEHAVEAWGNVHNMDLRKLIKSNDDDFKDQRDIFIRHVCERLERKTNELMGRESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBE3</accession>
    <name>A0A6A6PBE3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_397555</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBE3"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000146">
        <property type="entry name" value="C2H2 type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000181">
        <property type="entry name" value="C2H2 type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000239">
        <property type="entry name" value="C2H2 type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="319"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="399"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="731"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="44"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="205"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="321"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2461301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="791" mass="83776" checksum="C46FEC7DD49C1CC0" modified="2020-06-17" version="1">MDDQHLQRGRSPSGGRIRHSASPSPHAGFDPTSLSAAGLGLDPSLSSQDQQFNTFNPQAGPQPSQFDLSPQFLSAGQTDPSFFQAAQAATPQRSPSPSSFAQQQQQQQQQQQQQTGNAFGAPNHFDATADPGANGGDAFDVQFYDPGSNPQDQSIDPSFLIGSLDHQQPPQDQSIDPNLISQMATTSAHHSPTPPHLLQPESMRHPSQSVSPHNSPHLNQGGFSHHASPNHSRNTSLDPSSAAFPQGGPSMSGEWSAMSAYRNHRRTPSDAYSDVSSAQASPYMAHNDFDPNESPSPLLNAQDPMFQDLTNFGQFSISDNQQQQPQHQHQQQQQQQQQPQQPQGFSPHHSPQPSPRMSPQQQLQQFTPNNNFGLSPAMGGGQQYSAQEMYPGAHAQSMAEPFPSLQHGNGSGDLGGHADQMSPPEINIDFAPPSRQASFEPAKPASAATTDALSPPDRNRGRIRNRAKSDPFSNTSSRASTPGSGSGISDRGGSLSPHGLKAHGSRSPSPAGITKPSSSSRRSSTSAVPHRDYILDLADPSRQSPGSTAGGGVGGGGHGGHGGSKRTQKHPATFQCTLCPKRFTRAYNLRSHLRTHTDERPFVCSVCGKAFARQHDRKRHEGLHSGEKKFVCRGSLKDGGAWGCGRRFARADALGRHFRSEAGRVCIRPLLEEEALEKGWDAYGPGPGPGPVMLGSGAGPAPPGFLPAALLAQYPALAGLQWDALGPARPGDELDLSGGDLEAGDLSGRSSFDASSGGEMFDEEVEVDEGGEGYGGGAQVGHGMGNGVAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBE5</accession>
    <name>A0A6A6PBE5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBE5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16890" checksum="36EA4DC880AFFE6C" modified="2020-06-17" version="1">MSYCSTSHKTNPTPAIIIQRSIAPRKMKNSQKNFRNYTSLLKLGPSVLCSAKLFNPLSQSPTNPNRTNKTIHDLHFCLAGPRRRNQSVRLKSDSQSSKGQDKVRKSKSQSQAQARKVLENHAKIKILTSRNCKRKWTKKSKNKASQSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBH9</accession>
    <name>A0A6A6PBH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_268272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBH9"/>
    <dbReference type="OrthoDB" id="152248at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19059" checksum="A1B7AD4C27181B7B" modified="2020-06-17" version="1" fragment="single">VKIKSVTYGGTGCPQDTLNVDINADASLMPLYFSRYVAAVGPGASVTDQRKFCQLNIELELPAGFQFSIWRAEYHGYAQLERGVAGSIKSTYYFSGETDQTSSEITFAGPFTGQYTKNDEEFITSWSQCGGTTMLNMKTQLALTTDNANASGVLANDELDGHVTNVLHAQWRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBU9</accession>
    <name>A0A6A6PBU9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBU9"/>
    <dbReference type="OrthoDB" id="2562743at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974:SF2">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="40814" checksum="11B93AF469A32874" modified="2020-06-17" version="1">MSVEDKVTEAAPQNAHYLTTLAATDHAPPALQQTLHYLNDLHKNISATQREIKDAEMKTQLHLKDHEKYRDSTVRRFAHRLGGSKSKERFAEKADKEEREYYEAAQAEHQAKDRLVVLQQQLEEAHQQRCILEKQVKIHREAQQGLDALYESIFGGSTPEFPEEDSAECAMREARSKYDDLSAKTGTSSRAVELVSKALEAMDQALVQMQEALKYSRADIWIGGSWADALERNALSKAQNYTNQVQMHMLRAQHLRPEIADVGSTDIAQGNLISDVLFDNIFSSMNFHEKIKDSDVRLKRARGKLVEELNKEKQRKDGLNAGLNEAREQLESTRSELQRVREQVFRKVTGTKQDEVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCA4</accession>
    <name>A0A6A6PCA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hypervirulence associated protein TUDOR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_368717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCA4"/>
    <dbReference type="OrthoDB" id="2138648at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021331">
        <property type="entry name" value="Hva1_TUDOR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11160">
        <property type="entry name" value="Hva1_TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hypervirulence associated protein TUDOR" evidence="2">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="9163" checksum="2A5F5101FE239B33" modified="2020-06-17" version="1">MTEKNQPSSKQGEPIEEGDHVYTRIRGGRHEGDVERIVTTQDEAEEEGVKNPPKVIFTDQKGKRVAHNPGTLDITEEAEHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCG3</accession>
    <name>A0A6A6PCG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL17m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_412921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCG3"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.10:FF:000005">
        <property type="entry name" value="Probable 50S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_bL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047859">
        <property type="entry name" value="Ribosomal_bL17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="23220" checksum="16D6A9CAFD7E1DBC" modified="2020-06-17" version="1">MAGGLVKYRHLGRKSSHRKALLRNLVTSLFEHESISTTWHKAKETQRMADKLITLAKRNTEASRRRAHQIFFRPLEMVPKLFGPIRERYADRPGGYTRVLRIEPLKEDQAESAILELVDGPRDTRFAMVARTLARDRDMGRAEADMTELTAKNLAKVTRYTGETGRSRLEEMVLAMRERMKGGPPEEAKKTKGVSCGIWATILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCL5</accession>
    <name>A0A6A6PCL5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_314390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. Sedlin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCL5"/>
    <dbReference type="OrthoDB" id="18320at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14854">
        <property type="entry name" value="TRAPPC2L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044760">
        <property type="entry name" value="TRAPPC2L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19051" checksum="F0FFF845FC04112B" modified="2020-06-17" version="1">MSSRSPAIACIGIIGKHNNPLHTSLFPPPPARDPLDFSFLLSSSLDVFDARAPLKTADQDFGLLTAVDDRLAMYGWLTNTGVKFVVVVDMEGRPAGIASSGIGGSAAVGLRDADLKPVFRALQTAYIGLLRNPFYEPDDHSPVSANVVGRVGSTQITSKKFIAEVKRIGESWAPGVTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCW6</accession>
    <name>A0A6A6PCW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_277820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCW6"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="288"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="210"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="371" mass="40833" checksum="E9F1645D872D186C" modified="2020-06-17" version="1">MPPQQPLEDDDTYNSNSDVDFDPTAQLEDSSDTSSSDDDGPNRAATVERKRKRPTRTDTDGDVRMGEEGLDSGDEATIQAALKRKAKKRKAAGEDSDDEGGEGGLIKTRAQRRTEHKERRPLARTEGATADINTIWAKLSSAPVGRPPSSPPQQPSGTGANGATTVSSNITYSTEDTVTIKRVTKFAGELITEERTVPKSSAEAKLYLSEQAAKKGKRYDNEEREGATSTTVGGGVEADGLSRHVQDNEEKHESKSKLRRPLRRPSRFDPNPAGEVRSLPPELQLRWPRAPATTKFAKPTLGVRATKLNTVEKSRYDWAGFVDKEGIAEELDEYGRSKAGYLGRMDFLNQVEQRRDEEWRAAKAKGTKETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCZ7</accession>
    <name>A0A6A6PCZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_329753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCZ7"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40257">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40257:SF1">
        <property type="entry name" value="DUF1330 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30205" checksum="20D95415B0FBE18D" modified="2020-06-17" version="1">MPLITIHVLALNHSTNISTFLATIRNRTTLTPLVTSRVVRWIILPRTSRTPSSTAALLASNTHWDILLILPTAEASLPQPLSDLISRKWSVTASIPSRLLKDFASKNEKLLHPTPGSIPSAPSLNSSPAQSGDTGSSQSLELSPELLAWAHSFAQGTGSRAVSMLNLLAFEPGKKESYLQYGKAFAEKVGKKKGGVAKLVGSVVGEGGVGKKDQGEGKEWDEFALAHYPSIEHFVDMLRSGDYQEANRKYRIPALRDTFILCTTEVGLEEESKGMGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDS0</accession>
    <name>A0A6A6PDS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_359937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDS0"/>
    <dbReference type="OrthoDB" id="4684900at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="21500" checksum="B89C99105FF7D0BE" modified="2020-06-17" version="1">MSGSLTWTYKDTPILHQSKEALYEDGSEALYKVTDVGLSSFEWTPVAKWENLTTETSGFEQAFAYNPQPIVMSGKDVNDQWDFCGKIRGAELRLWEVGRSFGEHRDGTTVTFTARTNVAPNSAVYLYQKEHRFTPQVWFRLYAWENEWTVARRDPEGHLPLTLLGTVSVRSDEYLMTPAPLEQYQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDT0</accession>
    <name>A0A6A6PDT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endocytosis and membrane growth and polarity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_368272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDT0"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000005">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="388" mass="43967" checksum="B46361CB62D021A2" modified="2020-06-17" version="1">MNEAPIVLDGGTGFLKAGYAGQNFPDHQYPSIVGRPILRSEERTGDVVVKDIMCGDEAAAARSMLQITYPMENGIVKRWDEMQHLWDYTFFEKMRIDPTGRKILLTEPPMNPLKNREQMCEVMFERYGFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESTVLNHLTRRLDVAGRDVTRNLIALLLRRGYALNRTADFETVRQIKEKLCYVSYDLELDQRLSEDTTVLVESYTLPDGRVIRVGSERFEAPECLFQPHLVDVEQPGIAEFLFNTIQAADVDVRSSLYRAIVLSGGSSMYPGLPSRLEKELKQLWLTRVLQGNPERLNKFKVRIEDPPRRRHMVFLGGAVLANIMADKDNMWISREEWQEQGPRALEKLGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE16</accession>
    <name>A0A6A6PE16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_6755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE16"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="97" mass="11684" checksum="46072A665C2474B1" modified="2020-06-17" version="1">MGFLICVIEQLVSRTLPFFLSLPLFCFYPFHTDAAFLRPDSWFLKGREKTERSDKNNLLWYWLQHYIDQRAKYALCRAKAFTHYPGCAWKRVRFIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEK3</accession>
    <name>A0A6A6PEK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_8201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEK3"/>
    <dbReference type="OrthoDB" id="3250044at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF39">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="34812" checksum="12BA322DCE9868CF" modified="2020-06-17" version="1">MAESPDSFFKATSDPTAKDPKTKFPLDGYDILKVPKVELVAAAATAPALHALSSTRVARVSQDLVIKSSHSVLPSEAEAMKMVSQKTSIHLPRVYRSFTIQGTDGIYDSTGYIVMDYVDGCSLTDCWSGLTVREREDIVKQVVDIIRQLQSLRLPKPGPIGGGPSKGTWFSCYGAGPFANRSEFEEYFNQRLEIAKKTGSGGTQGHTPPFRFSTFVMTHLDITPRNLILDPKGRLWLIDWGYAGAYPPIFEPATLACQSECPDFNDLVLQRLAYDDQSFQQLIGIRGVLHFRGAIDVCHFHALLNFSVIASFANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF71</accession>
    <name>A0A6A6PF71_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Poly(A)-nuclease deadenylation complex subunit 3</fullName>
            <shortName evidence="10">PAN deadenylation complex subunit 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PAN3</name>
        <name evidence="15" type="ORF">BDY21DRAFT_5766</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The N-terminal zinc finger binds to poly(A) RNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. PAN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF71"/>
    <dbReference type="OrthoDB" id="204958at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3700:FF:000001">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000520">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03181">
        <property type="entry name" value="PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25586">
        <property type="entry name" value="zf-CCCH_PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="280"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Knob domain" evidence="10">
        <location>
            <begin position="568"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="529"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="358"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="419"/>
            <end position="420"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2462013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="665" mass="73628" checksum="F73EAC31AE7CB294" modified="2020-06-17" version="1">MATSLGDSLNDARRGVPSPRPPKGRENAKNTLCRNVTIFGHCKYANSGCAFNHDPSKFGNSPNSHQNDSAKKKFNVDSPSFTPLQPASNGASSSSRSATISPKAANAAVFTPKRAPAKTNLVSPQPQPKDMNTDWGSHDFPDFVPQTFDTSQLAADPTASAAAMNSYDPFSVSSTMAGLGGASHQASLNPYSQDAANLGGAAYFQSTNTFTQPLQYHLYAPLGPHRENLAPYQRTVHDFFIPDNLREELQRKAEATLQVLPNSTLPSVDHFHSLVPLDTTNQKNAALFGYPSWVYKAMSSQDGNYYTLRRLEGYRLTNEKAIRSIDPWKRLDNGSIVTILDAFTTRAFGDSSLIIVTDYHPLAKSLAEHHFNFNQRFQGNRSPQNFILEQVLWSYIVQIASALKTIHSHGLASRMIHPSKILLTSKNRIRLNACAVLDIVQYDNPRSITDLQQEDLVQLGRLILSLATNSPNAMLNIPKSMEQVSRIYSEQMHECLKWLLSPGPSASTPQSPSANALLNIDAFLAGISTQMASVLNASLNAEDTLLSSVNRELENSRLVRLLTKLNFVNERPEFENAPQWSETGERYYLKLFRDYVFHQVDAAGHPVIDLGHVLGVLNKLDAGTEEKIMLVSRDEQNCFVVTYKEIKRSLEMAFQDLIKASRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKT6</accession>
    <name>A0A6A6NKT6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_259478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001720">
        <property type="protein sequence ID" value="KAF2452249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKT6"/>
    <dbReference type="OrthoDB" id="195446at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="207"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="343" mass="38373" checksum="0E18FD09FA9A9035" modified="2020-06-17" version="1" fragment="single">MDPLSATACIITILQLSSKVFGYLNNVKDASKERAKCAVEVSNLQTLLLKLRFHLEEGSADTPWYTAISDLAIENGPLNQFKQALETLRNNMTDGRRLKKTGEALVWKFKKEEIASILDRIERLKTLVEIALQMDHLATSLMHRSKLSQAIKDDTNFVRTHVPVLQYGVDKIRQEQDSTSHRRLLEWISPADYPAQQSDIINRRQQGTGQWFLDAPEVATWLREAKGTLFCPGIPGAGKTMVAAIAVDQLLKSVQNSSVGVAYVYCNYKAQEEQDASSLLAAILKQLVQAQPSTSEPVQRLHKKHSTQGTKPSLDEVFGALRHVLTHYSAVHIVIDALDECRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKW9</accession>
    <name>A0A6A6NKW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_174562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKW9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="17326" checksum="5CED072C1146D6F8" modified="2020-06-17" version="1">MASSSSRVRQRSVKREEEGETVGPGASSNRAVDHDRCVPWLRGGADRHARRLASAPGPIGQSQNTRARALAGNDVAQRRVARSQPLEPHHSPPGRFHLAPRDNHLRDRARLQNNGTNTSVCCDGHPWATGYACLRPHRLRATSLLNAVQMRHTEKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKZ1</accession>
    <name>A0A6A6NKZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_359526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKZ1"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000191">
        <property type="entry name" value="mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="163"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="207"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="427"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="460" mass="51365" checksum="C999A3A0FF17AC4B" modified="2020-06-17" version="1">MPPAHGGRVPTGYAQELALSEATFRNARRSAISADGPPSKKRKREQRGDTSIVDGPGSYKGPWAKYEEERPDAESDEEGADVEVEYVYEEDDIEEQPAAPKTLAGTDYAETGDGSEKTTFLGSSERDYLGRTYMHVPQDLGIKLTGDIVDLKNYHPKKQIHTWRSFSKAITQMRFLPDSGHLLLSASADGTVKIFDVYHQRETLRSYLGHNKSVGDIDFNYDGTKFLSASYDHKMKLWDTETGTCVGRYSTGKTPHVIRFQPDPALSHEFLAGMSDKKIVQFDTRTPGASPVQEYDYHLGPVNTLTFCDENRRFISTSDDKSLRAWEYGIGVPIKYIAEPYMYPLVRSSPHPNGKSVAFQSADNQIVVYASTDRFRQNRKKGFRGHNNAGYAIDVAISPDGGLVASGDSGGYVCFWDWKTCKMYHKISASDSAVVSVQWHPRETSKVATGDLNGVIKYWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL31</accession>
    <name>A0A6A6NL31_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD-binding Rossmann fold oxidoreductase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_375598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL31"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000132">
        <property type="entry name" value="NAD-binding Rossmann fold oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000017">
        <property type="entry name" value="Oxidoreductase family NAD-binding Rossmann fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF11">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09900)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="3">
        <location>
            <begin position="137"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="39063" checksum="D9ABE63C564A70C9" modified="2020-06-17" version="1">MGVQKLKIAAAGLGRMGKRHAINFLHRTPRAELVAAFTPDEAETQWAKTNLEPYGVRLYDDYDAMISQEGLQAVVIATVTKVHAEEALKAMEKGLHVLCEKPISTDVSICRKVVDAAKAKPHLKVMCGFSRRFDSSYRDAYEKMDAGVIGTPTIFRSQTCDKHDPSPFFLEYSAQNGGCFVDMTVHDIDLALWFFGDNLIVKSVAAAGVAAVQTGLRDLGDCDNAVGIVEFWGGKIAYFYNSRMMAHGQEDTTEIIGTGGKLVVNGNPQANLVNTYTSAGIIRETPPHYYGRFEYAFVTESNEFTAAVLDNTKVPLKLSNAIRVVEIGSYLQEALSTGKKLYFNEAGQRVEQPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLT5</accession>
    <name>A0A6A6NLT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_155158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLT5"/>
    <dbReference type="OrthoDB" id="4159781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="45841" checksum="81FF3ABAF1D42C15" modified="2020-06-17" version="1">MAPTSVPLDLRSQSPLIRTDWLSSALSNKAFIHSMFCAAAMHMYVLGKASAIDIMHHRAEAVAALSLLLADSNTSLADSNIAAVFSLLCVEESLSSAPYYSPLHAAWEKSTDQRAIHYNGLNRMIALRGGLGSLKTNKCLQSFILWHRTVHAIALCQRADIDLDWVTEQALSPSAHLSHHPGQHNYMAEMCRVIGIEHELLNLVVQLESYAYTVSRWYSKTPSDMCPWALQNAACILECRLLDYLSTISSIAGDSPPRLSPGTPPLQYQRPPSPSSRARIHMLAHTALTTALLTFTICISEPLSRPFYSFHISLISRLRDALQSLSVADFAAAPDVYFWILAVGAFASRGSREDRWFKSTVDGVYDGVRAGHGKIGERGGVEWIVDRAKRCLWVEFVLDMWVKKLVESQSSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM11</accession>
    <name>A0A6A6NM11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_172945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM11"/>
    <dbReference type="OrthoDB" id="10035502at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052288">
        <property type="entry name" value="GH45_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730:SF1">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02015">
        <property type="entry name" value="Glyco_hydro_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025576718" description="cellulase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 45 active site" evidence="10">
        <location>
            <begin position="33"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="274" mass="29804" checksum="176910B8C1905758" modified="2020-06-17" version="1">MDLIGRGNALKSLALVLAASRWATADSLSGSARTERYWDCCKPSCSWSDHGRFMGDPVESCGIDDAPLTDFTAGTGCNGGSAYSCATQSPWAVNDTFSYGFVGVYIDRRTEDHWCCSCYHLNFTEGPVAGKTMIVQAHNSAYDTDIDDNKFTIAVPGGNTSFAGACSDQYGVPESTFGVENQGVRTRDDCQNLPEPMIGGCMWRFDWYENAENPRVDFKRVSCPSELINITGCIRRDENDFNSTSSASLTRSTSHSLVASLFMGGALAIFLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM13</accession>
    <name>A0A6A6NM13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM13"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="92" mass="9703" checksum="A618A2F9F292A867" modified="2020-06-17" version="1">MQCALFSSVLSFPGFLLPARPPNPRSNTYYVLVCSMVRVSSPQVDLASCPSLAPGIVGGVLFPALLAPARALIYPAAPSALPDPDARQEFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM36</accession>
    <name>A0A6A6NM36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_173744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM36"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="23266" checksum="E7AF6F37E7C603C3" modified="2020-06-17" version="1">MRPSTRHGLAIGKSQARYVGRPADRRLEPITRHIYDVQSRGSPVERIRGHCAAGFPVSGRRCGPLGPGTHGQELADPPMISSINSITLCFLCAFVDSQLASPQPLPLATDSAANEASLLPTRGVRRILGGRLREATGGLSPQQILLWYHLTTAKLPRRIFPTARYTLLLQPWLLRRHAANAVWSTPCVRSQTLSSPRCPYCVSSGVLSGELSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM42</accession>
    <name>A0A6A6NM42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoplasmic reticulum lectin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Protein OS-9 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_311611</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
            <orientation evidence="1 7">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the OS-9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM42"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0430">Lectin</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025335930" description="Endoplasmic reticulum lectin" evidence="9">
        <location>
            <begin position="21"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="10">
        <location>
            <begin position="160"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="468" mass="50571" checksum="B2F912F51B0C5234" modified="2020-06-17" version="1" fragment="single">MKHFWVLSALINLALGGQHAFSVLDDVLAFPQYEVVFSDSYISEASAESLLAFASSTAPRPQSTPDGAVNDANDAAGKDSSSTTGYGDSDAPGAAPGASDAYQTMRLHGQRYLCTIPAVTAAGGPNQTSEAGETAAVDEQERELARASDRGWELLRGMEGNCIYFRAGWWSYSFCYGRQVKQFHALPPGRNVPSYPPTEDPTVHSFVLGTYGGGDRRSGAGTRKRLDGGPGRGEGEGTAEADGSTPGAEVARLETRGESRYLVQKLVGGTVCDLTGKERKIEVQFHCHPQSADHIGFVKEVATCSYLMVIYTPRLCNDVAFLPPQKNKPNPITCQEIVAEEHVSDWLEAKSREAEDLLREMAEMTGQERPVVGGVEVGAQFDVGSEGRVLEKSVIVGGGKEVELGTIASSDGRVMAEKDLRRLEITNMKEIDALKKILQKKAGDKPWKLVLVETPRGKEFRGIIEPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM94</accession>
    <name>A0A6A6NM94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM94"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="16075" checksum="F7EA86BB6646578B" modified="2020-06-17" version="1">MEGERRPPSAPPACLFDRATSPAAPRYCARLPLLLPAAPSPPRQVQSAPACLGSPAQRPTKPPSPPLLQPRSPHYLTCPLPKPSPTPSIHRPRHHAAVDPPASSPLFFLPSSLSCFLFLPLSAAPPTRTPPAAASLPFLPGSLSRRRSCLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMA3</accession>
    <name>A0A6A6NMA3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_294755</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMA3"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="27"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="384" mass="43077" checksum="EAF5A76166017671" modified="2020-06-17" version="1">MTKYALRDTGLAIICGLPVLALLFTCLRIYGRRKLKAKLGWDDWLIVTATILSFALIGPSVKNYYMWHIGMHIWEVNPRELEPDYDDYYPVLLSFNLLNLPIVPLVKASIIMLLLRVGSVIPSIRRALYAILVFNVGVMVIPWCFFIFMCPPRTGNTWAPRTFGGLHCVGRDRLGEMLIFVTCANLLTDLLIFPIPFLIMHKMMNTNIRTRVIVILLFASSLFVTALGAAKIYTSYRDRLFRSSKPDWTYPIDFCVNHAENNVAIIVGCVPALRGLISRWVGRRGSSTEVDFVYGTRNAAAAAMSPIQDEPFSPRTDYTDPEKLEKDVLVATEVQVNNSHTKSNSSHTFDSKLSETTTAVAERKPSSRSSAELVPPVPPKDLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW4</accession>
    <name>A0A6A6NMW4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_358532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW4"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000017">
        <property type="entry name" value="Oxidoreductase family NAD-binding Rossmann fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="140"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="39253" checksum="A47F876BBDCD96A8" modified="2020-06-17" version="1">MSSPKLQVAVAGLGRMGMRHARHFATLTPKADLIAVTSPVQAELDAAKAEFGNVRTYLDYDQMLQQEPTLQAVVVASATVVHADQAINAIQRGLHVLCEKPLSTSPEISQSVVDAYRESLKSRPAQKVICGFSRRFDASYRDAHKRVTSGDIGSPSVFRSQTCDKLDPSGFFVAYAEFSGGIFVDCSIHDIDLALWFFGEDSKVKSVSAVGITAVQPDLRKHNDRDNAIAVVEFYGDKVAQLYCSRMMAAGQEDTTEIFGTSGKIAVNTQPQLNLVNLYEPTGIRRELPADYYGRFREAFIAEANEFTACCLENTPVPMELEGAVNAVKIGCALQESLVTGRKIEFEENGKRIERANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMX0</accession>
    <name>A0A6A6NMX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_143929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMX0"/>
    <dbReference type="OrthoDB" id="3789926at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="129" mass="14472" checksum="BF4FADBB4C37214A" modified="2020-06-17" version="1">MSFSGMWDDCDMTVEIKESSVAYVAMALFGVHIEVEFQTRHIMGAVIQTPNPTVTLCDIHEQALTNLFGPEIFQAIDTSLLRWQEREEGIRATRCVRMEVSSDPHSSALVKLKLELEQAIRIGTSLGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMZ8</accession>
    <name>A0A6A6NMZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_145097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMZ8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="19195" checksum="E91F31EB31D16A3C" modified="2020-06-17" version="1">MDSSCVRLQIAGRKVPLVEISLKAFLLRSLKCYSRIAEWRFAHSNRSSRSDRLRRRSCCRNPLSTATKAPKLPCEYQDSWTLGRRKYQAGQFRSPDVEHTAAVSRGKNLSNLPQRHPSIWPGHRRTLRYKSRAATPLQIPAEPCSLTNTRFQVKQTSSMLVEEAMGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN41</accession>
    <name>A0A6A6NN41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_293525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN41"/>
    <dbReference type="OrthoDB" id="5412502at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="380" mass="42040" checksum="D465AC438A0369BC" modified="2020-06-17" version="1">MLEFLPDWTDLQLDIVGFLAILGEGSVLSNAQVATLSWLIFLPRLLPAPQALLRPSRPERLESTLGWATSVYAGNHRDYITHIGDVLIDGDAMPNFSVRCVEIEWVDREREVKAKRKSVLALLAVTGCAMAIALLVLSAVLNDGMALVATVTLSFLSTIVGLGNKWKLRLPQASKGTDLPKGDLVIRYPKGNFVIVKCKEDVARSLFFAPENIDYLVEDPAIYRLISLIGTMLLMVGVVCLANAQLKMQIAFAAAYMLLNAAYWIVAALPVRKLWDTDCFLIKPHAFAGSNDTKKSARKARNFTEALWLAILATKTVNWVRQSQAAPDTPSWRGWLSEAEQRARDAPTTLDGKTPVYENSDWDPHKTLQEYLKDGAVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN77</accession>
    <name>A0A6A6NN77_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_374955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN77"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF6">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="49"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="582" mass="62772" checksum="07B73E7D35AC3E8D" modified="2020-06-17" version="1">MQRALEEREELLQKVSARVAYSTPRRRRAGRVDDKATPASFRSLPNKGQLFLLALCRLSEPLSNTCLLPYLYHLLESIQSPPPPSATEDGNSHNDGDAVSAAHISRLSGLLIAAFPLAQFATSMLHGHLSDAHGRKPTVLLGLLVSCVANLFFGFSRSIGALVFWRVLAGLANGNVGVMRTMTAEIARERKFQTRAFLLLPLVFNTGMVAALALGGCLAEPVVHMEWLFGPEGILNLAGNPEGVGWMVEYPYALPGVVNAAVLGGTLALAVLGLRETAPGKEGEDWGIKVRRIMGRAWRRLISSDQPVGYTEVQSDEPSDTPQEKDGFEDDDVLSKHTKAPAPRHRISFRRIWTREVVAAITSFGLLRLHNSAFMHTFAVFFSLPIAANKHPTAISFTGGLGLPSASVGLWLSLVGLAGIPLQLLAYPRIQARLGTLGVFRVALCLFPPVYAAAPYLALVRPAAGVARWMAIAAVLFVQVVARKFAIPSTVVLLTDAAPARSVLGTVHGAGNMVSSLARAIGPAVGGLVLSWGMERGVVGVVWWAYLTVMAVVALGWSYAMKGREEEWEGKERETGLDEDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NND6</accession>
    <name>A0A6A6NND6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7708 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_150017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NND6"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7708" evidence="2">
        <location>
            <begin position="188"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="463" mass="51498" checksum="52451283218A57E4" modified="2020-06-17" version="1">MPRKRDMFKRFLPSKPTSGIPSTTAPLSSAIPTTQIPQAGPVDSQSSHLTAPGDMSADPQSSRTAPAQTSRVPSPARQTTPDAQIQPQASQSTASSQLSPPPASSSSGPRRDLWEEALQTLPEDRRDAITSLSSAQTPQPGTLSARMDALIGETKQRQQECEKRSYKFTLNGREIILRDVAEKTITWLDIFKSIGDVAANFDPIHTALPWAGVRFLLQAAVGERDQMRGLLVGVERIVHVTSRCAVYEELYCVTPTPGGSLDNLQMALVKLYAVILQFLAQAHYMFGRHALQRAVHSVFRPGDIAGFLENCRESEQEVDLAASNCGQEWGRAAHAENKASMQALQTLLGDMKKPILRTDDRILALLQRVDQSERLEILDWISKVQHGENHDTVRESRTPSTCEWILQNRHYGEWQDASTSIILWLHENRKFYRILLASNSQVECANILSSRVREDVSNIESNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NND7</accession>
    <name>A0A6A6NND7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_374986</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the importin alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NND7"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.690:FF:000003">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000021">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="167"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="336"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="552" mass="60582" checksum="811D198659BED0FF" modified="2020-06-17" version="1">MAERYIPEHRRTGFKAKGVFKPEELRRRRDEQQVEIRKSKREENLAKRRGLANRDGSAPGAALGAAPDSDDEGGNIETQLNEELPEMVAGVFSDKIDDQIQATTKFRKLLSKERNPPIERVIETGVVSRFVEFLRSPHTLVQFEAAWALTNIASGSAQQTQVVIEAGAVPIFVELLSSHEPDVREQAVWALGNIAGDSPACRDFVLQAGALRPLLSLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWQTISPALPVLAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVTGDDVQTQVIINCGALPALLSLLSSTKDGIRKEACWTISNITAGNSNQIQAVIEANIIPPLIHLLQNGDFKTRKEACWAISNATSGGLQKPEQIRYLVQCGCIKPLCDLLGCPDNKIIQVALDGLENILKVGDMDKESHEGASGESLNRYALFIEEVGGMEKIHDCQNNANEEIYMKAYTIIEKYFSDEDDREGLNDLAPQQGQDGHFGFGAQQQQGGFSFANGGEQMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNN8</accession>
    <name>A0A6A6NNN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNN8"/>
    <dbReference type="OrthoDB" id="3745836at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29795" checksum="4DFFB215CFA517FD" modified="2020-06-17" version="1">MPDDSFSIAVYTPTELASQPALVHAVVELVNNAYFGHGDFEEEARFKRDQALIDNIRENGLCAVVVDENANDGDAPKVIASVSANVWKEAEGEPSLNYELSAVATLNSPPYRKRGLVDRCTLALQSALLERLRPSQRPDFRLWLIAVEHLNGAYWRRRGYKHVRTRVMPVGTWGARREFELATLVKRVGGLEGKDDVTPARETPEEAPVSALTPKEKDAAVPDELQRRSERGMATKTSRETVGEWMAQVVWVRTGTLLEQVVGGGPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNS3</accession>
    <name>A0A6A6NNS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_292926</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNS3"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="404"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="476"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="55413" checksum="DB919DAEB84D7327" modified="2020-06-17" version="1">MSLNWGSYLNDDGLNASTSNGRWPDISQQRPQPNRPLNRTAASTPASAAAAAAVTSAAAARQTLSLAPSASDISPFQPANQPDNYFSDAYYGNPDSYLLGDLEILEPLGHMMAGGSTTDSSPEAIMDAAELTNGPASRKESNASELKNSNSVTPNTASSSMSPELNSVSSIALETAQNRQFGSLFPNRAQPVYVEDLTYTSAPPAPVTAKKSTSGGSAIPESIPEDEPIDLTTAASSATTTTKRQKAPSSADSISACWTSPLCPNHSKDGSHPDPSTCGGECAPYLFAPGGSLANGTLGDIILGSSSGDGATARALSESSPEGEVEYRPRLKRSESDSSAVSGGGRVFVKPGATELRPRPPVKEESSESPQDYTGGPAAPSVAEEKKPAGTAGNTAPSSTSTQRRRLPHNQVERKYRESLNTQLDSLRRVVPALQQNNAQRTAAAGGAESGGGGGSNGPDIEDLPAPTKPSKAVVLASATAYIKQMEKEKRQLADENALLRSRIKALQALVKCEDCSLMQYVMDLKINNQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPF8</accession>
    <name>A0A6A6NPF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_355714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPF8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025407700" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="10482" checksum="D73356BBFFBEBC88" modified="2020-06-17" version="1">MRLQCSVLGWGACCLLAGAGTESADRVAGGWHGGRCRGVTGGGRIASRQPSCAALRLLPVRHPPARSRYSPPTDDKTMTIDDNDQTEPGARRLGARPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPP1</accession>
    <name>A0A6A6NPP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_293252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPP1"/>
    <dbReference type="OrthoDB" id="4117572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1390:FF:000007">
        <property type="entry name" value="p53-like transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF1">
        <property type="entry name" value="PROTEIN PACG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="58"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="58"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="396"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="547" mass="58612" checksum="E4771EFF85C2CE67" modified="2020-06-17" version="1">MNVVPQLLPPGPLDGLDHGSNFDAETYAGSEDAQYGPPQGGFQSHNPQLKRYPSAYDDPFSETLSGYEQQLRADANGAAADAVERGDKLLGFSPPNIPYTLLDYAHMRTTISISAQLHGMFFLAESPWATAGDAGGQPTELTCYRRNLFQITGNITLPRHLSFIATDHNEHIPIAVSELTISATESVEGNLVKIISVPWKTPAGATNAAAQQQQQTEEKTEKEPQSITLDPSSAQDVNDNLVSIPIVWKRLQFRIATANNGRRKELQQHFVVRLKVVATVLTTGQKMPICEVQSGPIIVRGRSPRNFQSRNDFPISGSAASASRAKLPAQPSRSSTGESHPRSGHHAHQKSTQPAPSPLDMPSTTFSFSYDPATAAPDLNVSPDFFDWKMMPTPTPGPATALPPDTPASYQLGPNPGYAQSSPDLTRTSMPPGGGAQLATPVNAPISLSLTDDEPTGKTPSGGGGAAASSTSPSGRPPSFSLNLITSPGDESADLLYEYFPLGLDDWMPPVDAVYRPHVVHHMNLPSDPKALAVKGRSKRYFAEDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPR8</accession>
    <name>A0A6A6NPR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPR8"/>
    <dbReference type="OrthoDB" id="1290869at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="219"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="309"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="700" mass="78940" checksum="F914E121BB92EC54" modified="2020-06-17" version="1">MGPVLVSGRLCLNRPVRQLPFSIPYARSRAIRNAPRTFVSSANPRTPLRYGYIFRIPPPPKSGYKAIIAGAAASLTPAVFVKLGESGVEDEDKTGEEQMLEASRAELQGQRPKALENSKSFRINVYWVVETYFVEPICTGLRFLHLVIIFVPVLLAVPAIWCGTRLADKGGERSGTIWWYGLLVRSMERAGAAFIKLGQWAASRTDIFPNELCMIMSSLHSHAPAHPLSKTKKIVEQAFGGRLFDEIFDEFEEEPLGVGAIAQVYKAKLKPDLATPSQFDVDEPKDFRHRVRKNVEAALKSTPSRVPSSYVAVKVLHPKVERIVRRDLRIMAFFASLINVIPTMEWLSFPDEVKQFSEMMRLQLDLRIESANLTIFRRHFRDRTTAWFPYPYIEYTTRQVLVEEFAQGIPLEAFLENGGGVFQKDIADEGLDAFLHMVLIDNFVHADLHPGNIMVRFYKPEQIDVPRLPFQKPKAVRPEDSLDVTEEVLQRLRPSNKNPEEWKAQLASIDAEGYRPQLIFIDTGLITELNATNRRNFLDLFKAVAEFDGYRAGHLMVERCRQPDAVIDAEVFALRMQHLVLGVKSRTFALGNIKIGDILNEVLSMVRTHHVRLEGDFVNVVLSILLLEGIGRSLDPNLDLFAGALPILRKLGTQSGASMVRGGDFSMLKVWAGLEARTFLQASVEQVENCVKYDLLSPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ60</accession>
    <name>A0A6A6NQ60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA repair and recombination protein rada</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_327633</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecA family. DMC1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ60"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000709">
        <property type="term" value="P:meiotic joint molecule formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000056">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000239">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011940">
        <property type="entry name" value="Dmc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02238">
        <property type="entry name" value="recomb_DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="94"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="272"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="337" mass="37019" checksum="246ACA8EC137D457" modified="2020-06-17" version="1">MAGSVASEDSGDDNFIVDIDTIQAHGIGAVDITKLKANGYYTIASVHAATRRTLLKIKGFSEVKVEKVKEAIAKCQPTVYGFVTAQELGQQRKRVVRVSTGSKQWDAILNGGFQSMSISEVYGEFRCGKTQLCHTMSVIAQLPKDMGGAEGKVAYIDTEGTFRPERIVQIAERFGVDPEQAQENISYARALNSEHQWELLNTLSMSFATNEYRLLIIDSIMACFRVDYCGRGELSERQQKLNQFLSKLNQMAEEFNICVLMTNQVQSDPGASALFAGADGRKPVGGHVLAHASATRILLRKGRGEERVAKIQDSPDCPEREATYIITNGGINDPDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQJ9</accession>
    <name>A0A6A6NQJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_381632</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQJ9"/>
    <dbReference type="OrthoDB" id="21018at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine/threonine-protein kinase haspin C-terminal" evidence="10">
        <location>
            <begin position="481"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="51"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="654" mass="72911" checksum="BF2298984A41A491" modified="2020-06-17" version="1">MPPKHVYGKRPRAVKSAVFDWSSPDLDKTKVQETQKERARSKTNMGAEMSRIADRLKHLGLEESKNDERDARRVLKKKDANAGKAAAADKDKASGDASKPGQQLSVVVHEVPADAGGEAGDEAATRLSKTKSRARATSAASSTKVRATTDSESTKSAASRPARKLRSRSAVRRGSPQPSDSSAAPPGCPYTAYTKHLLRLGSTRGSRPIPFAEWSDSLTAHFDVIKIAEASYGEVYRLSLNKPDPRFLKADESVIKLIALKPAPVPEPERPLSHKLSAYAKRRLAIKELRISQMSDPSNVVDEVRLLQRLSSIPGFTNFRDATVVQGRPSGAFCKAWKEWNVARPINKKSTFPDPSWKNGYEDDQLWAVVEMQNAGSDLEHVGVQSVWAAWDLFWGVACAVAKAECEAELEHRDLHLGNVCVRNTRDQSDDALSDPEIREVERKRIGFTGLETTIIDYTLSRARMDDGAKGLAFLDMSKDRFFFQGDGSFDYQYNIYRYMHDIHLDGRALSIVEDDDRWERGIRPDWSRYIPLTNVLWLHFVLRTFLITIGAIPQPKDHFIAGSSKPKPNKGNYLLGKLAETENERNALAKAKELDKRLKTLDEALDPKNLMIKDVSENQDGHCAFQSTTELVAWAITEGWLKEKDIVSLGCGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRG0</accession>
    <name>A0A6A6NRG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_326519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRG0"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="374" mass="42290" checksum="7BD735A0C987EF7E" modified="2020-06-17" version="1">MSTSQADVTQRQYLTPPSSFTNEPLTPPLTDKKPFAGALRVIAFFRHIQAGRNIQQGTWIEFQLVQGEYDEIERTLQQDDVLAGYVKDKIRYDYDGDKRRLVVRMPTRVHELFIDEVEDAIRTQLKTIRGGPGRKAQFAQKVRPARSTEIQFATSSSSSKSKYEPDASFWHDDAQYPGVIIEVAYSQKKTRLGRLAENYLLDSDASVRVVVGLDIEHGKKGSRKATLSIWRPRLFDTADGSELRAVEEVVDKAFRDDKGDPVDHPGLRLRLSDFAYEELAQDEIGDEDTEICISGVQLCQYLAAAESKAWRAQSLGKHSFAHGVKKRKRSETPPEEIMSGDEARYVEDEQKAVKRTAGHDHDYMDTSSTNSLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRN7</accession>
    <name>A0A6A6NRN7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRN7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="17519" checksum="FC0A3D097543BA1B" modified="2020-06-17" version="1" fragment="single">DKNTARRLSAGGRGLLRGLRHHTTSDHLGLGPAAPMRQRTQICNASLRGPDSTPNAGPELSFCCSFRAPFDRLEPRPSCPPRSPAVALGQRGQRRRGASGPKGTLPYPPCPRSPHDPPRRGSSPKPHLTDNPPRPLCCNLSSSVRIYYVCMYVPPVGANLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP9</accession>
    <name>A0A6A6NRP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRP9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="95" mass="10687" checksum="5479E6B0681451A2" modified="2020-06-17" version="1">MPPTRLFLFNLWFTSLAVYDDARRLRVLQRWYFISLAAVSISLDVLLIRSIQMPEESASAAGVFTTWLVPATFFGHLICSQAVQGLHTLRGSLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ0</accession>
    <name>A0A6A6NRQ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="28614" checksum="74231B698FBAF2C4" modified="2020-06-17" version="1">MRELDRPIAQVGRSHATATAAVERAVPPSHRGRKPGVPCDYGGSPDRKKAGLGGAGHEFSMIPLGRGGSRQTCEPANAVCTRKSRRKSVQMQGPRERANAIDQIGGLEIRKEPRRKRRFQAEEQVLGWEERSLGWRGRKAEERAEPVRDLPLSAAATSSSRARTVRSFPPPPLSLSRHGHPFTPTLLTHGGCPPHSVLHALRSYAFWHLPASLPPYPALFDASVRDADAAARARSQPRHGTVTGPQTTRPKSPPLQCPRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSA6</accession>
    <name>A0A6A6NSA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSA6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="11986" checksum="332F4AC4005E2F56" modified="2020-06-17" version="1">MKTWDSTAALGTHSRPARCCSHAPPARPPPCQPGLIYLESTRYVNSTYVQDQPAPPAGSQGPRDGLSGPLRSMDLPGRANTSTMRYRSWTPWAAMVPRACADKPHFRAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSB6</accession>
    <name>A0A6A6NSB6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_387430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSB6"/>
    <dbReference type="OrthoDB" id="2148442at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050019">
        <property type="term" value="F:L-arabinitol 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF12">
        <property type="entry name" value="L-ARABINITOL 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="12">
        <location>
            <begin position="44"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="11">
        <location>
            <begin position="196"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="356" mass="38349" checksum="21BBB90D849CE1C7" modified="2020-06-17" version="1">MSTATTIAEPARPNVGVFTNPNHDLWVAEAQPSLEEVQKGHNLKPGEVTVAVKSTGICGSDIHFWHDGHIGDMIVRSDHILGHESAGVIVAAHASVKALKPGDRVAIEPNIPCHQCEPCLLGRYNGCQNDKFLSTPPMPGLLRRYVNHPAMWCHKLPDNLSFEDGAMLEPLAVALAGIKRAGITVGDPVVICGAGPIGLVNLLSAKAAGACPIVITDIDEGRLAFAKELVPGVRTHKVVFSHTPEQFAEEIRRLMKGAQPVLALECTGIESSIASAIYAVKFGGKVFVVGVGKSELKMPFMRLSTREIDLQFQYRYSNAWPRAIRLVQHGNAVEAFKTASDPKTGAIKVQIQNLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT97</accession>
    <name>A0A6A6NT97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="7">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_366124</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="7"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT97"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002055">
        <property type="term" value="F:adenine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000004">
        <property type="entry name" value="Adenine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002636">
        <property type="entry name" value="PRK02304.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF3">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="13">
        <location>
            <begin position="171"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="298" mass="30348" checksum="EA43D112AC80F2C2" modified="2020-06-17" version="1">MSSAPPPPSPAQAPSAAPPPPSTTNTTSATTTASTTAPATTSAAPPSSHRSASQLPATSAHPPRDQPDPTVAVSSSSPPSTAAAAALGRSSHAAQGGFAAAAAASAAELARLKVSLRAALRQFPDFPEPGILFEDIMPIFADAGLHDALVRALEVQVRRDYAAATAAAAGADRPVDVVVGLEARGFLFGPSLALRLGVGFVPVRKKGKLPGPTETASYKKEYGEDFFQMQSGGVKPGQRVLIVDDIIATGGSAAAAGSLVRQLGGTLLGYLFILELDFLKGRDKLDAPVHTLLSSQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTR0</accession>
    <name>A0A6A6NTR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_80391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTR0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17193" checksum="454B9526E4BACFE6" modified="2020-06-17" version="1">MRPLSGVCSPARPRHRCAWTPAPSAVPRAVWVKRRKTCVSSRPSGPSWARPWPQRRGKEFFWASRMYKTPCLVSTVVAGNWSSSPQRALHSSPTFPPGPSSTVVPGQSIVCLSSFANLLSGRVRFRLAIGPSEIIPTPPPDCAAGHTIELSPLNLVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU99</accession>
    <name>A0A6A6NU99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_74277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU99"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19183" checksum="7346D08A64B7ABA0" modified="2020-06-17" version="1">MLRLSGGNGRPGLGTNQPRGGPGGSAVEHLDQDADSSALPHPSAAPCTRAAAAQWHLPALSPHAARCSPTAAKVKKLRRPHISHGIAPFHTPSHAVRSPGARCLTRKFRLPIRPEGQPSSPESSPAHASSQYRASICGLRNWCCSRRSFIRLLSPSRYFPAGKTFQTFPRSGCNIARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUP2</accession>
    <name>A0A6A6NUP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit A-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_289544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUP2"/>
    <dbReference type="OrthoDB" id="2193432at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000037">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="6">
        <location>
            <begin position="34"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="163" mass="17473" checksum="D8D7D084369B4158" modified="2020-06-17" version="1">MAGPNNGAVGIIGQPVIPKNPGFVLEGDGDRVLSKRKLDELVRQVTGGDEATANGAHVPGGALGLGGREESLSPEVEELMLSLADQFVDDVVTNACRLAKLRDSPQLDIRDIQLILERNYNIRIPGYASDEVRTVRKFQPAPGWTQKMNAVQAAKVMGGKTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUP8</accession>
    <name>A0A6A6NUP8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_325146</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUP8"/>
    <dbReference type="OrthoDB" id="2192830at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="107"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2455194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="31652" checksum="AD7F2439B05D80B8" modified="2020-06-17" version="1">MPICIECRYPVHQLYTTYSRADDRALGKGVRLTQCPRCKGFADKYVEHDFVVLFIDLVLIKPQVYRHLLFNRLGREDDRFDPSIIRLGTLLLLFDVYLTWARIEKASSPPSSHSTSLSSPFSPSVSSSSPISTGGGPPTSTNPLFATQPLFVQYLFFLFLCAAETVAFHLPIRLLCASRARAIPLLPHYPHPVPLSTALLVSSCTKLFPLLLIIWPYDLPSSASAVSWAVIVNNVAALEILLDCGYARAGLLVGVGAAVRAVVGGVVLGAVGLSDGGAGGVEGWGWGRWRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUX8</accession>
    <name>A0A6A6NUX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CipC-like antibiotic response protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUX8"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15031" checksum="906DDE4F00AC765A" modified="2020-06-17" version="1">MARRDSHEAYKEVAGSDNQANFGHELIAGGAAFAGFKAFEDHQRRKGKPVAHALAKELLAGFAAAEVDKLAETKGADHVDREKAKHHATRDAERMYDEHYLEGQRAGEYDPRRYGAPRRINEEYGTRNYGEGGGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV06</accession>
    <name>A0A6A6NV06_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_387205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV06"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF265">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="28"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="436"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="59819" checksum="52780B77D544B229" modified="2020-06-17" version="1">MPFLAQEHMHIPTKDLLSWMFDDQAYGENKPVYIDAADPNRTICSRQAKSIIRKLAAGFKKAGLKKASIYYSMVFLGIVAAGGVFAGTNPSYTAYELEHAVRTAKIKMLVVEPELVSNALAAAKATGIPQSRIFIFNSRGQPVADGLQSWEALQQHGEVDWECWDDKVKSENTSVARLFSSGTTGLPKALDMSHYNFVAQHTLVMEYRPRDYVILRLLSNPMFHVSIVPRAHTSPLRGGYVTYVMRRFELEPYLRNIEVYQITEANMVPPMVIQIINSPLSTKYSFQSVRFAWVGAAPLDKEPQARLKAFLRDDTPFNQVWGMSETSCIATMLYYPEQDPTGSVGQFMPNLDAKLVDDDGHDITDYGVTGELCVRGPTVVKGYFDNEEANRRDWDEDGFFHTGDVAYRDPANKLWYIVDRKKDLIKVRGFQVSPAEIEGVLLRHRSIVDAAVIGVKFGRDGSEYPRAYVVLAKGARMTEKEVARFCNGRLARYKGLEGGVRFVEFIPKNASGKILKKKIRRWAERDLGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV09</accession>
    <name>A0A6A6NV09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_289325</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV09"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000228">
        <property type="entry name" value="Cysteinyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000186">
        <property type="entry name" value="Putative Cysteinyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="47"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="659"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="757"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="670"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="851" mass="94345" checksum="02D99EC8E96C33BE" modified="2020-06-17" version="1">MASSATGRTQPPWEQPPPPQEGVKLPPLKIYNSLTRSKNPFYPIDQQGKRVAWYACGPTVYDDAHLGHARNYVSTDILRRILKDYFKFELKFVMNITDIDDKIILRGRQQHLLSQFKEKHPKLDGEVYDAVTKAFEAYIRKNLPLLPESTTPESYPAESKNAYGRVLAGKALESDDGKPGDKEAKIKMHLKTCDTASKALASHKSFSQTPETFYAQTEDVLFPYLDSLHGSTVDSQDHGVWTRLTQRYEQRFMDDVRALNCLDPDVVTRVTEYGPAIVDFVRKIVDNGFAYATSDGSVYFDIDAFERAGNSYARLEPWNRGDKDLQADGEGALSAAKRSSEKRSDADFALWKSSKPGEPAWPSPWGPGRPGWHIECSAMASDVLGARVDIHSGGVDLAFPHHDNELAQSEAFWLETAAKGGAQHKPHQWVNYFVHMGHLSIAGSKMSKSLKNFTTIREALARGDWTPRSLRVVFLLGGWKDGVEITDDLVKAGQAWEEKVTNFLLKAKDLARELGDKAPAPATAEGEDPFAVPRDPDDPIAEPLQRTRDAVFAALADSFDTPAAMRLLSSLVTDANAAPHGAVPAATTLALARYLTHMVAVFGLDGTADPADASRIGWAGIDIPAEAEAWVYPLSRMRDTVRRAARNYAKEPTKVAEEARGAVASADEVATSQTKTTATENGSAEANSFEKVFRDFKDEVAGLASETASPAKYLSACDRVRDVGLWDCGVYLEDRDQTAQPALVRPVTVDLRAQREAKETVAREKAAARERREKEEAEKARKREESARVDPRVMFKEGDAAAEFEAWDEEGLPVRLKGGEEVSKSRKKKLVKEWEKQKKAFEEWKKGQGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVG6</accession>
    <name>A0A6A6NVG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_373127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVG6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="342" mass="35934" checksum="B146D1DA539E4AA4" modified="2020-06-17" version="1">MAQPTPPPQPAKQIPNLQQQFMQRSASRKTSHSSPSTPTRSTDAPPTPPNAAAPSPSSSPRPSKRARISDTTGPAAAEGPPPPPPSSELDNAVLVDTGAAVRAALAAEEEARRAALERAAEAAGESRWVLSFREEGGEGGGGRLASGEGDERGGLRVRVAGWGELDGGDEEDEADEGESQVAVVGRKRFGEWKTEPSAHEKARKEEESSEDDSDEDSSDEDEVDDAPAGAAADPSGMIRAERLRAERQAEREKKVNSAAAQMATGRRSHDFQPNSNRFMGISSGGGGSGLGGRGGISMGSRLSSGGGSADWLRNVECHRCGQKGHMMRECPNPRRGGTGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW64</accession>
    <name>A0A6A6NW64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_372897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW64"/>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000251">
        <property type="entry name" value="Ubiquitin ligase complex F-box protein GRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF67">
        <property type="entry name" value="SCF E3 UBIQUITIN LIGASE COMPLEX F-BOX PROTEIN POF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="72"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="6">
        <location>
            <begin position="204"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="548"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="640"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="667"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="705" mass="77295" checksum="04EDB1EFE5F8DEC1" modified="2020-06-17" version="1">MARPRRGHRLSVGSNSSSTSTSPERGIIDDDNDSFMMQQNDSQSSLAPSVPDEAADSAAREIEERCRVSPVCRLPAELMIAIFSKLSSPTDLRSCMLVSRDWARNSVGLLWHRPQTNNWPAIHNVANAIRRKQRYFDYPGLVKRLNMSSLGNQISDGTLLQFSDCKRVERLTLTNCNKLSDLSLTQMITGNRFLLALDVTGLESITDKTMLAVADNCPRLQGLNVTNCKKVSDDSLEAVAKNCRHVKRLKFNGCTQLTDKSILTFATTCPHILEIDLHDCRLLEDESVTALLSLGRHLRELRLAHCTRITDAAFLNLPQDTTYEALRILDLTDCGELQDAGVQKIVAAAPRLRNLVLAKCRQLTDRAVFAITRLGKNLHYIHLGHCSRITDAGVSALVKLCNRIRYIDLACCSNLTDSSVQQLATLPKLKRIGLVKCAQITDRSILALAKLKSPGHGGPLSPSCLERVHLSYCTQLTLNGIIALLNNCPRLTHLSLTGVQAFLREDLIVFCREAPQEFNDHQREVFCVFSGSGVNRLRTYLNEETRAHPFGHPHQQQLPGAFNVDGTVDADMDPDPSQQDVDGGDAGPAGQTALYDDGGNDADDEAGLMDVGAVLDPASASAPATFGGHAAAAMQFLQHLANQQQSQSQSQPHPAGDVAGMGFHAHPPMTQPSQQQPEQQPGLQQMTDSFDATFIDAMDEDMDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI1</accession>
    <name>A0A6A6NWI1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_365135</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWI1"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF94">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="939"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="151"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="509"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="619"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="832"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="996"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="449"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="560"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="586"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="676"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="728"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="888"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="902"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="942"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="944"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="955"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="960"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="966"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="969"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="984"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="987"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2455918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1016" mass="107346" checksum="BBDA18AE1F778D07" modified="2020-06-17" version="1">MAPRTHHHASSGASHPDAQATVSDFLDYTEYFPADLARSLTLIGKLDATYRESLQRVHELTTAYGQLPAQCRQHQAQQLSDEKPAQQAADATPTAAATPTIDPRILRAQISAALDHALHCRESAHAEAARLYDVAQRHATRLDIIKRKLQALPQPPSRDPTPAPAPAPAPTVSVSPTRARKPGDDHQQPQRSGARIQFSLSAGRRGDGAAVARARQQHRVRRVTVPGEVLPPPDPNSPPPSTVETDWSSTEEASDSDEDDIDVDALSPSGVRNSIEAIAPSQPRRGGKPGRVKIPKGPRSRPPKTPKTPRVRPPGVMGTNVHSAVAGISTSNALAKLTPPPADAKPGSRWAPWHKLTEYEMAVLRKAMKKNAIWAPSETMIRRELAAKGRGWENYEKAKAAAEAAGDLFLDEDPVDLSKKTLGPGETTFKPMGSTEEALFNRGMKLNEAKKLKKENQAREQAARDAMEIEEASKRIENAGNKIKNLFDTIDLTPTQQNQLQQHQIALAFPPPQQTPTPGFVASTPPLGFQRAATGSTTPTAEKRKEPPKSTKKRKRDSASADATTAAAATVGANPIAGDGVAPTGQSQSQDSSASPQQQPPKKLKIALPSLSSTIAAAAAGESTVTAPSPRSAASNTQPELMRPPPSAGAGAQQKEQQTPTRPSASAAQHTVTTHVPLLPAGPSAPSSPSVGGASATDTTPPRHTTTVKLRSPAPLSPTEIKIKPSLATAAARGATPTMATTPTPTATTAAGQRSRRTSLAAPRAQTPLDAPVSAGVRPRSRGGIKAASAEPSTGDGAGMGAPSGGLSVKRELRELRRASNVSMPASVAAAEHGGMAGGSLSAHGQGGVPQQQQQRAGGRRSKRPAPGALLQLQGADGEGSMGAKVSVGRRKAAPRKKGGRAGKDEERREKEKEKAAQAQAAAQQQHEDGWEDVDPDEPRYCHCGDVSYGTMIACENEDCEKEWFHLQCVGMTEIPGRRTKWFCSDCRKKLGIDERGQPAADLDEGVASAGMRGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWN1</accession>
    <name>A0A6A6NWN1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_373017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWN1"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="28805" checksum="62B6504BCC8F25A4" modified="2020-06-17" version="1">MADSGAGSAPKPSSSVKLVLLGEAAVGKSSLVMRFVNNDFQENKEPTIGAAFLTQKCTLPTRTIKFEIWDTAGQERFASLAPMYYRNAQAALVVYDITKASSLTKAQHWVAELQRQASPGIVIALVGNKADLANPSSGTDEEGAEPPAAPPSGPTDTDAPADADGAGVPADGEDASAPPSGADSDDGADGDDAAADARKVPMRTAKAYADEEGLLFFETSAKTGANVAAVFTAIANAIPETSLKGSRGGVGGQTSLGAGRGQEGDRVNLTGRAGDMGAKEGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWP3</accession>
    <name>A0A6A6NWP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWP3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="22507" checksum="EA7B25A11EAAB66F" modified="2020-06-17" version="1">MVCASVRGQTPWPWALRRFPLPFDHLGVEYPIFSQSVVTTMLGWAGMRSLRNYYRSPFGKDSAPSTTQRQKDELSWNRAGDLKGSTISALHLQQQVSILSVLPEGVRCCVYLILFAHSESEYRFHFRAFITMRVLSVELRRQPMDCHTHHCLVDLTVANCHYRRHSSTPRRLPVKTITRPSEQLSLTPHLHPDPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX25</accession>
    <name>A0A6A6NX25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_65708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX25"/>
    <dbReference type="OrthoDB" id="9995210at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="20565" checksum="EF1B8BC573C6A143" modified="2020-06-17" version="1">MADEFEGASPREQAVEAARRNNPELLQELIDKVGKKGGDKGSPEAVAEFLNTARDGVGYGLLHLAAMNGKYDVLDLLLDQEGVEIDHEDRMEKDTPLHKAVRFVNSLKPESWEDGKEIVDILIDAGCDPRIRNKGKLKPIELVDPRNKDLIEALRKAEWNIMYANDIPEAEADEDEGPTGSASDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXA9</accession>
    <name>A0A6A6NXA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXA9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="534" mass="56243" checksum="8E2DCA74B8BFD501" modified="2020-06-17" version="1">MPVRPAISSYLGGRPDVEPSLVGGRLSDTTKSGTPDVVSAHQSDLNINTVSLPKATDTAMDLNASLRSLSLDSVSSAASTSASSDLAVSSPSSPSSSPRLTSAHSPASPSYCATPAASSSSLCLSMRRLSPRSSKHFSAGLPPSCDLEQHVVNGHVTEGVNASASAHKYYHHRRAHSYTGDHHQQRPVSAYPPSQWRRHSHNNHHLHLGHRYNHHRRHQYSPPAPPVSGRVGSSNQDTPALLLPSPLEVDGEINPFDAMSPATPSTDGANDPADEPHRRGNNDADNDNDINDIPLPAPHHDDVFSYDPLRASAWMMPERLWARLPARLRPHVTALQMAAAAVETSLGRLDELAGEVGGATDGQGARADCGSGVSGSGPQTEQQQERRKDAAADDDDDEKAPPPSPPPTATATSSTTAASASSTATANRAQTPVPIRHSLAPHLPASYPPKLALAPHLGIDPLHPLALRLAAELAGLREGWAGGSMQASIDGRQVCAGLVVSGGDIHVLKRTALYGGACVSVWMVFVSRSLVRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY27</accession>
    <name>A0A6A6NY27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase P subunit Pop3-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY27"/>
    <dbReference type="OrthoDB" id="20109at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013241">
        <property type="entry name" value="RNase_P_Pop3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28272">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28272:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08228">
        <property type="entry name" value="RNase_P_pop3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26777" checksum="D273ED9AF1287C76" modified="2020-06-17" version="1">MTSRANPRPKAPAPVFKVDSPFVGPSWPHVSLADQHVTLNMLCSLLAPIGQYRKNRVVPSKGKRARKRKKRIEAAQDPAASASIPASRPHIESPVEIGLNSVSRRLELLAAQRRPSDESNNHLSDRHIAVVFLPKSKNDMIYSHLPLLSRTASLGRPDNFVTRLVPLSPMAEDKLSAALNLPRVGVVGVLEDAPQAGPLIEFVRAHVAAVEVPWLKDVADGSYKNPHVQHREASARSNVIPSMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYH5</accession>
    <name>A0A6A6NYH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5 16">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_304574</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Endoplasmic reticulum membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5 16"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYH5"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="UniPathway" id="UPA00282"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16 18" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2456628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="53362" checksum="8EF88CDA521A1BE1" modified="2020-06-17" version="1">MGPSAEPSQLEERASIQLPPRSYAAAVDPDVTPGRDGADGDGSVSSDELTGGELNDGCLGSSRERERSFGPQVNRTADDGKAVVFQKYGEGEQNGLASVKPTDDYETALRHGDKGRPRPHQAGERGELVSGRRAGSGWERSGIRWAPLNVPLKRRLQTLTVLLHTLSIVLSLTIFFFLCAIPLLWPIIVPYLIYILFSRAGVDGSLALRSERFRRSPVWSLFASYFPARLHRSAELPPTRKYIFGYHPHGIISHGAFAAFATEALGFGQLFPGITNTLLTLDSNFRIPLYRDYALRMGVASVSRESCENILSRGGPNGEGMGRAITIVVGGARESLDAHPHSLRLVLRSRKGFVKLAVRTGADLVPVLAFGENELYDQYRAIEHPRIHQAQLFVKKLLGFTIPLFHARGVFNYDVGMMPYRRPINVVVGRPITVQKKERPEEAYIDELHTRYVSELKKIWDDWKDIFAKERVTEMEIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYJ4</accession>
    <name>A0A6A6NYJ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S28e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_287487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYJ4"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="7739" checksum="6AFF6701C83E08BA" modified="2020-06-17" version="1">MDSTKVPVKLVKVTRVLGRTGSRGGVTQVRVEFMDDTTRSIIRNVKGPVRENDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYU8</accession>
    <name>A0A6A6NYU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="3">5.1.99.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_372362</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="3"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYU8"/>
    <dbReference type="OrthoDB" id="10064708at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NAD(P)HX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10260:FF:000005">
        <property type="entry name" value="NAD(P)H-hydrate epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032976">
        <property type="entry name" value="YJEFN_prot_NAXE-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232:SF10">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="10">
        <location>
            <begin position="11"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="250" mass="26621" checksum="E5FD28C690C665B4" modified="2020-06-17" version="1">MALRVLSAKSSAALDQELMSAGAFSIDQLMELAGLSVSQAVHKLQPLNKGRRILVACGPGNNDADGNCPAGPDAQTGGDGLVAARHLWHYGYQPTMYYPKQSKNELYQRLTTQLHALDIPFAQDFGAALAQTDHVVDAVFGFSFAGEVREPFPAVIAALAAAPVPVLSVDAPSSWDIERGPPPDGPGKAFHPQALVSLTAPKPLVKWFGGRHFVGGRFLSPAMAEKYGLDLPPYEGIDQIVEVPVEGQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYY1</accession>
    <name>A0A6A6NYY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_287080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYY1"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000014">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000030">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000047">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF36">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="174"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="460" mass="49567" checksum="DA1558EC6BCCB9AB" modified="2020-06-17" version="1">MVRNMVVLGGSSHPHLTEAICNHLGIPPAKILLGKFSVGETRVEIQESVRGKDVYIIQSGGGKVNDHFMELLITISACKTASAKKVTAVLPLFPYSRQSDIPYNKVGAPLARVGPGQPGGSAAAAAGGKPGYTFDSRPQTPYPGQAESAGLANGSDMLHRQLGRLQLDHRHANGVNGIAPTRQSTCGSEDNSNFANNNSSSSNSANSSTKRRSDTQDSETSNHSGSPLTKPPNFTPQRGYRQWVAQAGTLVADLLTCAGTDHVITMDLHDPQYQGFFDIPVDNLYGRHLLRRYIQYKIPNFREKGVIVSPDAGGAKRATAIADALGMPFALIHKERRPTQISDRQNATMMLVGDVSERTAILVDDLADTSNTITRAAKLLKKEGAQLVYALVTHGVLSGDAIERIKASALDKVVVTNSIDQTENARRCAKLEVLEVGNVFAEAIRRVHYGESISVLFNYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYZ6</accession>
    <name>A0A6A6NYZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_372401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYZ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="44"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="398" mass="45823" checksum="7D51FD6978D52101" modified="2020-06-17" version="1">MAARYIYENSATTFDVVGDGSFITSLNILTNKHIIGPQSPLLNDSFIFETAHGTRWVLRYDRFRQNMDLLSEVIERFFHEDSNFIGGRIPSYLLLLMDHDWIKPSIVLDKSTWTDHVRPGCMVAMSMEARVQRMFLADPGHCLRPTIPCFSSVPYRIHDPGLGAFVFWRAFHNVINNWVKESDNIPISLYHFVSRLFEVVRAIFLHNEVLWFYFNHLENANSLSQDNERYKRVHVWGDMITSLGHVPGSPRPSSSVGQTQSGAEASEESQRRHGALAQQLLVYQPEQPGWRRRRPVESLACWTSFQQPDVSRGEHVVRQMVRPVTDADRIRIAAESAWARGMLMPNLGPGVVNMEEGLVDACRWLAELFWGSEEENGKRIKQTTKWFLPPIIPDEPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ61</accession>
    <name>A0A6A6NZ61_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_287453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ61"/>
    <dbReference type="OrthoDB" id="3924760at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23722" checksum="4FF5940CDDB3D506" modified="2020-06-17" version="1">MLNPKKLSELLSNNVDPRLYPRMFLMSPNGTLIAYSTPVNIKELRDQAALISLVWKDYEEQKLPQGSSSSEASSTSRTLYTLTIEFSQCNILVRAVQPKMLFVLIGGVYQGHKQDFKITAEVDGDSRYPSGSASPCTGAPLPGSGTGNSSDQEYRKDLNLLSEGQSEDAAKDIHEEVGRVTIHLQRKKLEAMYAFIRSEFDSRGFVMPDNPSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZK0</accession>
    <name>A0A6A6NZK0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZK0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="415" mass="44372" checksum="29B72F929141DF59" modified="2020-06-17" version="1">MCGRPPTVLALESTRSARIIAGNDGVVGVSDVLRSMLVPAAALLPFWPSAGVLASPLSPPSPPAAGVSGVGVVVMEMRRPSRSSAIVDTLLFGLLLLLGGQFFTVAAEGWLGVGVGQSSWAAAVDEGGVVVVVVIASPISACCCEARIRAVMALRVLSNFSRSAFNCAKSSSTLLVMATSFPRLQHYTDSLRHYGNAERSTITWRVDVTGDIAGDVDHANVGVVEHTKKRKVGQSSRENPLNQKAYTLNEYLLGRRCGGNKQAPQRRMQDRHDRGEGKEGGEKKAARLRVRYAGRSLRCALAPACEADHRFLQHRRPAELVHVFSASSEAPWCIGGAAAWAALGPLGPRLQVAGESAGRAVAKRASPRAELMRRDGLTGVSLRPHNEDLSLSQSSRCWRGLIGHRDRGLTLILQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZP1</accession>
    <name>A0A6A6NZP1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Multidrug resistance-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_32881</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042592">
        <property type="term" value="P:homeostatic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000020">
        <property type="entry name" value="ABC metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000450">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="544"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1031"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1117"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1221"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="16">
        <location>
            <begin position="316"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="639"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="16">
        <location>
            <begin position="992"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="1312"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="868"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="873"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="896"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="929"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2457048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1577" mass="174732" checksum="EF8A568C8007CBE4" modified="2020-06-17" version="1">MLRSVEAQSPLAAAPAPPLPSAFSAPALAAQGYLAASAADGRQPLCRNAEGWGPLSPFRYDLTPCFLDVWIAAVAVFGIVGGAGALWLLLKRRTPQPVNKNWHFYAKLSILGALIAATVVKAGFQISYYGHLWIGDFRFWTSILTIVSFGIIFAVQYTEHWRSRNPNGVVLFYWLLLLIVYAIKLRSLIVQHTYKYHTPYFVIFCVNVGLAGLEFVLEWLVPRKLSAYDALGDEFECPYEYANIFSVLSFSWMTPMMKHGYKHYLTQDDLWTLRHRDTTRVTAHSFEEAWNHELETKHPSLWIAMFRAFGAPFFRGGIFKIGNDVLAFVQPQLLRLLISFVDSYRKDNAQPPQPPVRGAAIALAMFAVSVGQTTCLHQYFQRAFETGMRIKSALTASIYGKAMRLSNEGRASKSTGDIVNYMAVDTQRLQDLSQYGQQVWSAPFQIILCLASLYELVGISMLAGVGAMILMIPVNGLIARLMKNLQKKQMKNKDARTRLMTEILNNMKSIKLYAWTTAFINKLNFIRNDQELHTLRKIGAAQSFANFTWSTTPFLVSCSTFAVFVAIQDRPLTTEIVFPALTLFNLLTFPLSILPMVITAVVEASVAVGRITSYLVAEELQADAVLREPPVEEMGEETVRIRDASFTWSKEAERNTLEDINYSAHKGELSCLVGRVGEGKSSLLQAMLGDLRKVRGEVVLHGTTAYVSQSSWVMNATVKENIVFGYRWDPHFYDRTIKACALLDDFASLPDGDQTEVGERGISLSGGQKARLTLARAVYARADIYLLDDVLSAVDQHVGRHLINHVLGSNGLLASKTRILATNSIPVLAEANYIVLLRGGRIAERGTYEQLMAMKGEIASLVRTHNNEDNQTDSEAGRSSDSSPTSDETATVYDSPNEDEDEEEAEAAQENLPQLAPIQSGRHAAPTTRKASSMTLRRASSASFRGPRGKMADEEGAALKTRQTKEFSEQGKVKWNVYLEYAKTSNVIAVTIYLVTLVGAQTAQVGGSVWLKRWSEVNGEYGGNPQVGKYIGVYFAFGFGSAALVVVQTLILWIFCSIEASRKLHERMAFAIFRSPMAFFETTPAGRILNRFSSDIYRVDEVLARTFNMLFVNSARAAFTLVVISVSTPVFIALIIPLGALYLYIQRYYLRTSRELKRLDSVTKSPIYAHFQESLAGISTIRAYRQQKRFSLENEWRMDANLRAYFPSISANRWLAVRLEFIGSVIILGASGFAIISVSAGSGLSAGMVGLSMSYALQITQSLNWIVRQTVEVETNIVSVERVLEYARLPSEAPEIISRNRPPISWPSQGAVSFNNFSTRYRPGLDLVLKDINLKFKPHEKIGVVGRTGAGKSSLTLSLFRIIEPAQGYVEIDKLNTSTIGLLDLRQRLAIIPQDAALFEGTVRDNLDPRHVHDDTELWSVLDHARLKQHVSAMPGKLDAAIHEGGSNLSQGQRQLISLARAMLVPSRVLVLDEATAAVDVETDAMLQTTLRSNLFKDRTIITIAHRINTILDSDRIVVLSNGTVAEFDTPDRLVANRGLFYELVREANLLGAFDGSSGGGGASASGAPSNGTVAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZW8</accession>
    <name>A0A6A6NZW8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone-fold-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_286652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZW8"/>
    <dbReference type="OrthoDB" id="1272441at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000017">
        <property type="entry name" value="Ccaat-binding factor complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="81"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="297" mass="31986" checksum="29DCAEC723D2791D" modified="2020-06-17" version="1">MQQVPMQPGHNPPRYDGQNGNPLYDTRNGGHYGASASIAAAGKAPSPEVFQGQWSNVNQGLNGQYRDILNTYWQQQITKLEQDEHDYKLHQLPLARIKKVMKADPEVKMISAEAPILFAKGCDIFITELTMRAWIHAEENKRRTLQRSDIASALAKSDMFDFLIDIVPREEATGHKRSGGQGGSSGQQAPPTAPAPGGHPGQQPGIQQQPGVHPPPQQMPDYGMGQHMPGEQDFRSNQAMYGAAAPSGGAPGAPGGVQHGDPAAFGQPHGAPPQGMFDQNMYGAYGMPAQPVSDTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P088</accession>
    <name>A0A6A6P088_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P088"/>
    <dbReference type="OrthoDB" id="5336565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="573" mass="62819" checksum="2E91801CFD234C80" modified="2020-06-17" version="1">MHGRAALPNGCNSRACRNPALAVSSSRRQQVRAKRRASVASLRPSPQPPLAMAPSVGYNHRSSAALRTHHDPVVNGSYMPESQLSNPRKRQRTGQHLLSPPPSKRQKKLPQHTAGGGYIDTPAFWDSLSKIWLTKHALREFDRRNSRPHSPSRQARRLTTRNFLAAQKSTRQRISAADFLSNGAPTRLKEIKIFARRGGPDLSDLIGYPPSTPPDRKMSSSRSASYRNRGLSSTAKTKSTGRTTPASTTTGKTTSGLTKKSGTSNPGDANYQQRLIDGGTYPYGYKYPDGHRPPLSPNWGAANQRLAQYRASLSPSTFSEEKYQEFVEADADAFNEDEIKDSVLPAMLNAMGASSGARKNVLFTSIEPITDGITQAKPHYYYGARPEQIHKKIRDPDVPDNLISHIIPSNNDHLPAAPNFFMKAKGPAGSAAEARRQACHDGAIGARAMQSLLSYGQSEPVYDNNAYTISSTYHDGTLKMYGRSVAQPNGPGTRPEYYMHQIDTYGMTGNKKSFLQGATAFKNAQDMTRGHRNAAIARANEMAAQTVEEEEEDDDDSEAESSNLVHSFDCGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1F5</accession>
    <name>A0A6A6P1F5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1F5"/>
    <dbReference type="OrthoDB" id="5367584at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024312">
        <property type="entry name" value="TACC_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12709">
        <property type="entry name" value="Fungal_TACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="647"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="527"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="707" mass="77384" checksum="73CC1AE2D32356F2" modified="2020-06-17" version="1">MSPLSPLSSNVQNAKGAMSSPAKSAHVATDTPKSPNKASAASLGEDDVAWADAPSSPFIEEVGQENQSQVGGMNNMSQSQQLHSQHDTTTWAPHQSQDGSSSSQMPKEARDQHSRHHARSKLNSDALVLSITDADSEDGRPAVRQDKALRDNEGLTTAVKLMEMEREGNASDSSEIPMPDETNIDDTCFSTFSEVPTDMTTLARLGCNSPSKTFRMGQTPSLMATPATVRKAPYASTERSLSPTPRGHAGPRPENDTTNLLLDFTEQMESFSTSSRRSPTRTARTSPLKSQGEPKLLSYINDQRSPSKRGQTPRTPTEKKNILNLLDFELPPAPTPRSVPTITIRELESLKSSYLSQISSLNATLSGREAEVESLKKAVGDAERRVGEAMENVREEKCAREHVEKEKAEWEKRGIEVEEVLKSIKKEIICSEKEKEELARKLEEADRKAEDAEARAVEAETRAIEAEGRVPDTSELPDNGANSGPKFTAEQVQKQLDEKVATLCRELHTVYKKKHETKVAALKKGYEAKSEKKLVEMQRTLDQLSKQHEELKLEKNATLSGVLPSDLPTAEQTVDRKLLEKQKAEIEEQKAKLAGLAEELRAMRCEHTDLLQALQQERVEKGELVAAVDEMLALQAEAGTPAAVDDFRRSISKPSGLRGPGFTSASTGGESKIGRPLPSSGLSRSVSGSKSRIMSNIERMGSGRAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P234</accession>
    <name>A0A6A6P234_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid hydroxylase superfamily-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_302818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P234"/>
    <dbReference type="OrthoDB" id="1658724at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="143"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="35722" checksum="3677B58CE06E377A" modified="2020-06-17" version="1">MNSTTIVQPAALPDTYWGQFDEISKYNVQLNYAERLWLTWYSFMQNDVLATGVMSFAMHELVYFGRSLPWIIIDCIPWFNKYKIQNQKIPTAKEQWQCAMLVLLSHFTVELPQIWLFHPLAQFFGLETSVPFPSPFKMAYQIAIFFVMEDTWHYWTHRAMHVYPSLYKHIHKIHHQYSAPFGLAAEYASPIEVMMLGLGTVGGPILWVAATGDLHILTMYVWIVLRLFQAIDAHSGYEFPWSLHHFLPFWAGADHHDTHHERFVGNYASSFRWWDYVLDTESGPEASKRRRAKAAEKQKALSAKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2N7</accession>
    <name>A0A6A6P2N7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_285381</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="10"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2N7"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000006">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008854">
        <property type="entry name" value="PRK11892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="9 10 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="56"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2458047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="382" mass="41450" checksum="78244DAC0B9730F4" modified="2020-06-17" version="1">MSASRVFRPAARALSASRPTSFQSPVSLKSFRQPAAALPQYVRRRDYATAGAPKELTVREALNDALAEEMETNEKVFILGEEVAQYNGAYKVTKGLLDRFGEKRVIDSPITESGFCGLTVGAALAGLHPVCEFMTFNFAMQAIDQIVNSAAKTHYMSGGIQPCNITFRGPNGFAAGVAAQHSQDYTAWYGSIPGLKVVSPWSSEDAKGLLKAAIRDPNPVVVLENELLYGQSFPITPEAQKPDFVLPFGKAKIERPGKDLTMVTLSRCVGQSLVAAEQLKSKYGVEAEVINLRSIKPMDVEAIVKSVKKTGFMMAVESGFPSFGVGAELIALTCEYAFDYLNAPPVRVTGAEVPTPYAQKLEEMSFPTEQLITDYAAKLLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2P4</accession>
    <name>A0A6A6P2P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phage metallopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_371043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2P4"/>
    <dbReference type="OrthoDB" id="1884773at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18664" checksum="8441696698BA96D7" modified="2020-06-17" version="1">MPAVDLYIAYITDQAVGKYNLLPVWLVDALRAQKAFPTLDLGKVRYAEGIETMQGDRPITLEYNIFFPDTLNIADQNADRADVLAVLHELEHVAQTKRHDGVRPYCNKFIIQSAGAVSQSLQRRSWRAFVKNLHEYDGIEKDAVDKAKRLIDVVMEAAIRPPPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Q2</accession>
    <name>A0A6A6P3Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_385268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Q2"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="341" mass="38298" checksum="3C182D255E9DEB3A" modified="2020-06-17" version="1">MAGTQGDGSSERPRSVDSTTTTLAADDSVDHESLSDFHSLLSNTGSVKSTIFNYQYENGRRYHAYRAGQYYLPNDEDEQDRLDLVHHVFRLTLGGGLCATELENPQRILDVGTGTGIWAIEMGDEFPESEIIGTDLSPIQPPWAPPNVRFETDDARQEWTFPPDFFDFIHVRCMGGSILNWPEFLERCYKHLKPGGKLEVSEARTNLWSGDGPLPQDSFTAKWLSEFNRIVNSLGLEFDISPALPGFLDSLPFAQVKKMDKQVPITPWSENKTLKEIGRVMEIVMLGSGLSAYTLALFTRNGWKVPDIENLLDKVKEEFREGGMNIGTYFSYVTATKPAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3S0</accession>
    <name>A0A6A6P3S0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_385070</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3S0"/>
    <dbReference type="OrthoDB" id="7832001at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="10">
        <location>
            <begin position="218"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="9">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="52742" checksum="D75D08213073E5BE" modified="2020-06-17" version="1">MAPQLDSFFKQVDAMSESFIDRLSKAVAIPSVSAMDEHRPDVFKMGEFMASELRNLGAEVTLHPLGKQPHKEHLELPPVVTARYGSDPSKRTVLVYGHYDVQPALMEDGWATKPFKLTVDESSGRMYGRGSTDDKGPVLGWLNAIEAHKKAGVEFPVNLLMCFEGMEEYGSEGLDEFIMREAKGFFKDADAVCISDNYWLGTEKPCLTYGLRGCNYYSLEVTGPGADLHSGVFGGTAHEPMTDLVRIMSSLVDPDGKILIDGIDEMVAPITDQEKALYKDIAFTMDNLYESLGSKTALFDDKARTLMGRWRFPSLSLHGIEGAFSAPGAKTVIPAKVIGKFSIRTVPDMESEAVTAAVQKHVDKVFAGLKSKNKCTLKLQHDGKWWVASPNHWNFTAAAKAVEHVWGVKPDLTREGGSIPVTLTFEEATGKNVLLLPMGSSTDGAHSINEKLDRRNYIEGIKLLGAYLHYVAEEPMREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3T8</accession>
    <name>A0A6A6P3T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_340279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3T8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="62" mass="6381" checksum="93F73C2BE255FE49" modified="2020-06-17" version="1">MGCRMYGRARIVSGMSTELGMVAAAREERGRKGIRGADGSGCAAVGRLTAGLGSEPGWLIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3U6</accession>
    <name>A0A6A6P3U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_267098</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the hexokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="8"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3U6"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000034">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="10">
        <location>
            <begin position="224"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="504" mass="54058" checksum="3BBEE2DC4C57EC9D" modified="2020-06-17" version="1" fragment="single">LAEAAAKVAAEFEYPAEEVRRGVKEFMREMDEGLHKDGTSLSQIPTYVTSVPNGTEKGLYMAVDLGGTNFRVCSIQLHGNSTFTLTQSKVAIPRELMTAKTAKELFSFLAKQIEAFLQEHHNDHYQGVTRRKKEGAKVEEEDIFDMGFTFSFPVHQMAINRGTLIRWTKGFDIDDAIGKDVCKLLQDEIDLLDLPVRVAALVNDTVGTLMARSYTSPGKTGTLLGAIFGTGTNGAYVEKLEKIIKLSPSGDYDKSTGEMIVNTEWGSFDNAVAVLPNTAYDEALDADSVNPGVQMFEKRVSGMFLGEVLRRALASMVADPAVALFAPGPSAANPTVNSSTNVARDSPLFRVWGLDSSFLSLAHADSSPHCSVTRQALDRELGVSAASEEDARAVRAVAAAVGRRSARLSAVAIGAIVLATGALERPLPVEAEAGDQAELGVVDIGVDGSLVEFYPHFETYIREALREIEGIGEEGERRIRIGIAKDGSGVGAALIALVAGRMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P505</accession>
    <name>A0A6A6P505_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P505"/>
    <dbReference type="OrthoDB" id="5416172at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="18272" checksum="B127BBEFC15F576B" modified="2020-06-17" version="1">MLPISSLYLRLSCHSCLPWNDLFESWILATVQCASTMAPTSSNDPHAGGSLEEMAPSGTSIPNDAGNMRTIPSVPRPDQANATELGEPNMAAAADNPTDIPRQGRDTGATGGVITGTGHQMPATAETKDLHFKSGDPGAKGHLRDAKHSKESSELETKQGTAEPEIEGPVGDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5L2</accession>
    <name>A0A6A6P5L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfonate biosynthesis enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_282758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphosulfolactate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5L2"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003830">
        <property type="entry name" value="ComA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036112">
        <property type="entry name" value="ComA_synth_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413:SF1">
        <property type="entry name" value="PROTEIN HEAT-STRESS-ASSOCIATED 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02679">
        <property type="entry name" value="ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102110">
        <property type="entry name" value="(2r)-phospho-3-sulfolactate synthase ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="327" mass="35787" checksum="256D22998982907F" modified="2020-06-17" version="1">MASVRSLARGASAARVLTGASTAGPSSLARRAFASTAAPAAQKNPQILLEDKNDGFGFIRHNPRAPKPRSTGVTEIRGPYYTVMGKRYLQDILETMGYHVDGLKFAGGSFSLFPEDKLRELIDLAHSYGVYVSTGGWMEHVLTQSDVEAAVDRYLKKCKDVGFDVIEISTGFLSLPPSDWLRLVDKVHSMGLKAKPELGIQFGAGGDTEASDLESIGTSDPSKVINVAKQFVNAGVERMMIESEGITENVKSWRTDVIQAILKEVPQEKVMFEAADPSVFNWYIREFGVDVNVFVDHSQIVQLSCLRGGIWGKSDTFGKITTYRPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P626</accession>
    <name>A0A6A6P626_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Anucleate primary sterigmata protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_408530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255000at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024545">
        <property type="entry name" value="Mto1-like_Mto2p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12808">
        <property type="entry name" value="Mto2_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="5">
        <location>
            <begin position="461"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Mto1-like Mto2p-binding" evidence="6">
        <location>
            <begin position="1444"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="514"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="777"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1320"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1400"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1532"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="628"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="716"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="801"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1181"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1442"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="514"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1346"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1364"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1409"/>
            <end position="1426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1556" mass="172050" checksum="9EAC425A425F15B9" modified="2020-06-17" version="1">MSNNDDSTGLSSNDNSILSFVGPPAIDFPPLPEADEQENSDLLAPPSGSGDNSNVAGANNSDGSALLDEKEMKRKLMDVESSFLPDIEHVEETQPVGTDDTYLYGGSPGNGMRQVEQTAAEDSTEDSKARNISEKDVEFGMSGQEKESQLLSSPATPADAYKTPAPAQTGTESAGDYDEDVQRPENTVSTFGTVPSSPAAAAAQRNHSRGLSNPENRPNGAAKHDRQASADDAKSVSSFRPSSRASTIKAPGSPSYQDTSTVQTEEPSDQGMDTTRSESSNASTSRLRGRPSFLRSRQTSQRSSVSSFAGRSDVSGDAGSDLNSGVDFALQSGGAAPSGSTGHPSQGLSRLPSLGSITSSMSAMSDSGPSLERSKSARDRKLHRLTEEKRSNSGSPPETPRPGTSSANFAPTDTVIAQHIQNIRVPDTVAREYREKHDKKLSGGIGGTPYHGTRSTKSNLTLKEQNSKIDKLSKENFDLKLKIHFLDQALQNRSDEGVKDMISKNVQLQTELATEKKENQSLRRKVRDLERKVKAHEEGEAAKARSSGSEDEKSDSSAKQAEMEEEILYLREVLQHHETTIEKLREENMAKEVEKRRMAAYAKSMTERKTPDQTEGVEEAIDMWKDLLEAETARREQADEDAQKLREEVERLRTQIATQPPSAVTNNHSSRNMYTISKRNYMSQATRSQSGAGSDVGSEANGGLSASTAAVSSTLVEQLRHENAELRRDLGAQTSMLTSRNRERERLQQEIEDLKLNQRREGTRSIAGDSIFERSVSRAHQRSASRASGATRVSQFSDVEREEYEKKNATLRDEISQIKLLNQDLERELNAHLDMLTQAETENRALKEEKNLTMEDLQALQAERDEALENLEDKEAECENLRDEANKMLDRLEEEIEHKEGELARIAADLDNRNEDFASLQQEMKNVSESLIQLEDDRLTAQRKIASLEQELEDTNREFEALDKRFRDACAKNERLEVQLESTQGEIAFLREEQESDKIKIGELEASLNAAQTSVQEEKERFRDLEERLAAERRQREILDSQEKEEVQKVLNDLNSQASKAKDEVRRLRKNLSSKEVEATTWKERLDDLEQNLREALGDLNGTRSSLLKDVHKLQQDLDNTLQELDNTKTALAEKERVLRNRDALLESTGLESRRLSDMLDKERQARKQDRIQFEQASRVHQSTSRTINQHETRIMELEAARGNDKRKMAHLEQQYRDQLMDRNNLLFALWNRLSTLCGAEWAKNHSLINGELPSLDVIQRNLAGFNRNIISAVKTVESIVGGFRTRIRSIEKDLWREFQTLEHALDVRAKRMDQLEKAVLANQGGGRRGASRSADRSGGGTDGAEVQRLRNENRVLRAQVDAGSGGGGGRGSSRGPPAGGRDANRASMANTLLRHHTTSAIEGGGGSSHHATTTAAAGGAQAGAAPHDAYDEFNAPLQPTEQRWIHRLKELERRLKAEREARLNDRSGARRRLEEHALENDELRRLLEREREKGWVADEMGGGGNGGGPGLGVGGVGGGVGGGGYGGFGKRVGSERRGSVGSRGEPLVDAYGDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P638</accession>
    <name>A0A6A6P638_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_281926</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P638"/>
    <dbReference type="OrthoDB" id="10262653at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="116" mass="12970" checksum="7134FDBC9D7901A6" modified="2020-06-17" version="1" fragment="single">ANSGRNKKGRGHVKPIRCSNCSRCTPKDKAIKRFTIRNMVESAAIRDISDASVFPEYTVPKMYLKLQYCVSCAIHGKIVRVRSREGRRNRAPPPRVRYNKDGKKVNPAQAAKTAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6G9</accession>
    <name>A0A6A6P6G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Phosphatidylethanolamine N-methyltransferase</fullName>
            <shortName evidence="13">PE methyltransferase</shortName>
            <shortName evidence="13 14">PEAMT</shortName>
            <shortName evidence="13">PEMT</shortName>
            <ecNumber evidence="13 14">2.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_283239</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64573"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="2.1.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="13 14">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13 14">Endoplasmic reticulum membrane</location>
            <topology evidence="13 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13 14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.17" evidence="13 14"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6G9"/>
    <dbReference type="OrthoDB" id="4583at2759"/>
    <dbReference type="UniPathway" id="UPA00753"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004608">
        <property type="term" value="F:phosphatidylethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03217">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016219">
        <property type="entry name" value="Phosphatid-EA_MeTrfase_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138:SF0">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000383">
        <property type="entry name" value="PEAMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51598">
        <property type="entry name" value="SAM_CHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 13 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11 13 14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 13 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="575"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="338"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="707"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="719"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2459033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="965" mass="109186" checksum="F6A972AE2E6DA973" modified="2020-06-17" version="1">MSSAHDQDAAVDAPGLRERLPQHPDRPLKAESTDEAKRAVEDLNRAQGRDDVPEKERKTFGRTPDGTVFTVPQTHDMVSQLLSPSQPKNYSDLFVLAVLAFHILTLWALPPSFRQPVFAIVFLFWRACYNAGIGWLLHAQSQGRLLVSWAKRSKIFENPAKGNNKHPKLYALLKREMETKIPKDYKFEDAPIEYNTWLLFRRIVDLILMCDFVSYFMFAFACFNTPAGEGIAMTVARWAAGIALFLFNLWVKLDAHRVVKDFAWYWGDFFYLIDQELTFDGVFEMAPHPMYSVGYAGYYGISLMAASYKVLFISIVAHAAQFAFLTIVENPHIEKTYNPPALPRKRASISGDAVNGNQESDRPGSRNSDAPYAADYPSLGSATQPSPVHHLLGLQNIDLHRVTDVSVFLLQLYTFMLATLTPSSTFYQTIFVANAAIWRLWYSLGVGYILDRQSNKKNWTRHFIKYGEDTEEAWRQWKGLYHLSMTMCYASFIAAAYKMYSLPPDWEYGMALLRHVLGVALISLQIWTAVSIYESLGEFGWFYGDFFFDHAPKLTYNGIYRFLNNPERVLGLAGVWGFALITWSKAIFFVALLAHLLTLAFIQFVERPHMQKLYGEALRGDSGISKTIKRSLPGPIRQWHGNVDRVVNETVDSIEEFIETTRPKLAAGVQTIVRDSTALFKHYPARFGITRLARDLGGLDPKDYSLSIEGTTSAGEGAAMRDKSSGREGENARRPPQRTSEFRTLIFEYGAPIKVRWTAPANHAARDWIGLYMVSDNASREATRVSSQGRWIATTRGAYDNARADQGILVSSHRVAGTDRAAGEMEFAGDKLWWTTGVFEFRYHHDGMHNVMAISLPFEVRIGRFDEDDAEPDANGQVRGAVEQALLPVVRNCFDRDPEIAPRTVEEPFGRLEERDGKFAKRVVFAVHQMFGIEFAPEVVQADGNVKNLAWRICNAKKVLVSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6N4</accession>
    <name>A0A6A6P6N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoporin Nup159/Nup146 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_338351</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="248320at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026054">
        <property type="entry name" value="Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039462">
        <property type="entry name" value="Nup159/Nup146_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193:SF23">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16755">
        <property type="entry name" value="Beta-prop_NUP159_NUP214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup159/Nup146 N-terminal" evidence="6">
        <location>
            <begin position="46"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="463"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1052"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1161"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1348"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1264"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="590"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="636"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="682"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="710"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="781"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="828"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="914"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="938"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="965"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1024"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1056"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1166"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1351"/>
            <end position="1361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1480" mass="156173" checksum="EA42861219666F97" modified="2020-06-17" version="1">MALPQPNVAVGPDVSEILTEKLGFHAISGESKIRLLPSAWPESQLPPPTASLLAIAQKRGLLVAASPDSLVLAETAAVRAAFSATAPSGHEGNVKPFMPAASLRIPRVSHVSFSTDESLLVICAEQGGGLAVYDVAALLRNNREPAFQLATNGVAVRAIAPHPAADNAHIFALVLANGQLLVADLNGRRIHSGPNGPVLKENVSCISWSTKGTQIAAGLGDGSTVQIDPTSGEIKAQIPRPPGLEGDHHVSTISWLSKNEFTLVLTETRPQPDQPPQSTFFFVSRENNTANFTYRKALDPCFPAGITSRSPPHHFMSRLHGWRRTPGQADLKDAIMVASTVSGDIGLFTRSTQPLENDPLDPALVVDNFTATGMAIDSRRPQLPMTATESGDSSPIGMTLDLTSRKGVLGLPSDMVDADETKTPLPGLMVLNHEGVLSYWWVMYKDSLREAIPYPDLVAVQGQQPSQQKTATSPQPQQQVTTPQQQQTPSGFPKPAMGSAFGQPAFGQPGGWGNRSSWGSPGGLNQTGGAAFGKPAFGTPAFGSSSPMGSTFGSASGVGQRSSAWGSPTPAGGGQQQQQSSTPSGGGGFASFASGTSGFKAAPSPLSSMGGQSDSSGFSSFAKLGSSGGGKPVWAQPSSGQDNQEPVKSFGTGSTVTLGSSFGASAQTTSSFGKPEAPTPQQPSFETSTSEMTDVDDSMQGPGDREATPTPGNLQGTAATHQGQKEPEKPKGPFGMGTEGFKLGSTFKGDGTAKDEKTPSATGGSMFGAGFGQALTGQTESKLEENKGSAKEKGDEGLVESAFKVPTPSQQHEGGGLFKVPPKSAFGTEKKEDVKEKRWEEEVVPEAAPLPPDPTTYKPTQPADDDIPPIAGSPPVKVEAPESPISSPLGPSESSKPATAEATPVKPTEATPTRPEETPQKPEETPTRPEDTPFKSPETVTQKLPSWSFTSNSEQPKAPTPLKPPAAVKSPGWTPAGFPPAGAIPHFPPPQQQVQESPRSPSPSRRVAPGGRALSPIRRGQSPVIRSSSTPITSANASKQPITVPAAPAIQNQYAAPPPQPPARPQTPPLIDEDDERVREELAKDIPCKTTLPPFIAHTDTAPPLPTDAASVDVSSSSKDHRMVLTAQIRRVYRDINSMLDCLGLNNRAVASFVRGHSELASGAQRTRDDLRDASTKPPGTEGEWTLVELDDLISIVSELEAARQRADYDREGIIEDLDVANRNATSMRANVARLRREIEARADPTHMERAIQAPLAPDQAAVRNDLRKGITELRGKLREAEEGIAVLRAQIASREGNGGNEMNRLTRTPAQVPTVEAVARTIRKMTSMVESKRSDIDVLEAQMARLGIDPSKEDVPEVGRRSRSGTPGTRQSQVQNGFRPSASARWSRSGDATPARTTKGPFFTPDSNTKASFAGSGSPLRRSGRFSTGTGGGMGPTGAVDDERIKRYLERQAKRKMVKETIGKALEEIGFRTAPGRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8I1</accession>
    <name>A0A6A6P8I1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_160788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8I1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="170" mass="17818" checksum="EB835BEF5312CE5F" modified="2020-06-17" version="1">MHPCLPRMCPLYRGTNATSSHERSPQFRVGGALVLASKMVLARASGLAPDGTRACVPSSLAAGASPTIRSRPFTSAPGASASGSLSLCHLCIYSPSLPTFYGLVKPPRAAAALRTSPSLLPSRIFALPPSSWRPGPFLGQRTAARDGMLHGLQLKQLQKVVYPSAPSTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8V1</accession>
    <name>A0A6A6P8V1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_383986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8V1"/>
    <dbReference type="OrthoDB" id="3431704at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF28">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="602"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="878" mass="95623" checksum="1402FAA8E6F95FD0" modified="2020-06-17" version="1">MSPLATQPVENPKADATQPAVPRKRRRRAAATGATEDCFTCRKRQIKCDRRRPYCTQCIDLGKECSGYRTTLTWGVGVASRGKLRGMSLPVPKSPSAQTSPRSGDCKAGSTSPARSVPSSASATTPAPEHLQPPPVDFGQPPTLPSSPHSSTAFDFGGSNATSPIPIPSAPTSNAGWHVPGFEEHVEGFSTTGNKAARGSFHPGPLQRLHTSLAQSYDDAGMSASTGSLSAYSDSDFPSPSEYPQTPEELPLIEPLVPQYGDMYLHQSMAMNSSESLPYNEAPRSYPVSAEEVSSSIRSVQGGQGFMDSSSGHSGTFGTAILPDAAIYRDERNSASGNALRLSGNVHSSQLFNLSPRMHFLLDYYDKAICPVLVAFDGPNNPYRAHILRQAYTNESLQNAIAALSLNNRRMRGTSDIRRLTMGEYAHSGSPSDAQALAYRPVTTEGLQQVHGEPSAEELRYKATSIEQLNQLLADPHRAKDDSVLATLLVLCLFHVCDSGFTKFKTQLAGVQKLLSMRNASESRSDFVNWIEVFFTWFDVMTSAVNDRETEMRGDALDMPNLSANLGALEHLAGCEGRLFKLIARLGRLNLLSQNRPVSNDAGCFSGQTTPRASPPLAGPRHQQQGLGGGPPGHATFASVGLHSLDRLDGNGWGAPLTDAPEESPWEVEDPRRDFWREWRDLRDRLEEWQLGPEEVEEGDGNVCGSNINNNIGLAMGAGGDGAALADRRDVRRISESFRAAALLYIERLAHPEAPAAAGNIQALVARTLSHAAAIPVTSCVNKFLLWPLFMAGTECIDGAHRALVRQRCIEIQRESGFFNNLSGLEVLEKTWREDDERAAAEAARFRHHAPPGRERRQPQAFRWRRAMDRADGEYIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8X0</accession>
    <name>A0A6A6P8X0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fructose-1,6-bisphosphatase</fullName>
            <ecNumber evidence="5">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_165445</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="5"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8X0"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000009">
        <property type="entry name" value="Fructose-1,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="14">
        <location>
            <begin position="20"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="15">
        <location>
            <begin position="213"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2460441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="351" mass="38189" checksum="06D16999F5523B12" modified="2020-06-17" version="1">MNGNGDGGAVGQEKINTDIITLTRYLTEEQAKHKEATGDFTLLCHALQFAFKSIAYYIRRATLINLTGLAGSSNTTGDDQKKLDVIGNDVFVSAMRSCAKVRILVSEEEEAAITFPQHPDARYAVVCDPIDGSSNLDAGVSVGTIFGIYKLPEGAPGQKEDLLRPGTDMVASGFTMYGASAQLVITMKGGSVNGFTLDNALGEFILTHPDMKMPKKRAIYSTNEGNSLYWEEPVKEYVNGLKYPGEGGKPYSSRYIGSMVADAYRTLLYGGIFAYPADKKSPKGKLRILYECAPMAMVFENAGGQAVSSKMQRMLEVVPEHIHDRSGIFLGSYDEVQKVIDVHKKHGIVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8X1</accession>
    <name>A0A6A6P8X1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_335289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8X1"/>
    <dbReference type="OrthoDB" id="110024at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000110">
        <property type="entry name" value="DnaJ domain protein (AFU_orthologue AFUA_2G13210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056453">
        <property type="entry name" value="HTH_DNAJC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23302">
        <property type="entry name" value="HTH_DNAJC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="17"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="343" mass="38816" checksum="D8B32C109F8B358B" modified="2020-06-17" version="1">MAPKFEDLADEPPSSIDPYAVLGLEHDASADQVKSAYRKAALKTHPDKVAGDEKEGAHAKFQEVAFAYAVLSDPRRRSRYDATGRTEETLHPDDVDDDFNWTEFYREQFEDVVNFDSINQFASEYKGSEEERNDLLAAYERFKGDMRKMYEVIMLSNPIDDDERFRTILDEAIKKGDVEAFPQYTQESERSRKRRVDEAGKEAKEAEVLAVELEEKKKNGGKKGKGSTKKGAKKDESANGTVELMAMIQKKHQSRASNFLANLEAKYAPKGKKGKRTREMADMDEPPEEAFQKTAERQKKAKIDKNGVLAEETEETGEADDAAEDEGPSRRKTRHSKKTKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P913</accession>
    <name>A0A6A6P913_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_162815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P913"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30229" checksum="3C64DF07B1A7E25E" modified="2020-06-17" version="1">MPPLMESQPSADGERRRSSISMIPDALYGDKEKKTWVILGASRGIGLEFVRQLVARGERVLATVRKKWAGHASALWSQAGGDHGRCQMFICDILSEKSIIDFVAELSAIPGLKIDYVVINAGVMRYPNRATEASFDEFAFHLHTNTIGPIITAQKLLQSKIPIGTIAFMSSDSGSAGAFRDIEDGFAAYASSKAALNQALRHMAAELKRKNDDTVILAIHPGEVATDMANIDLPWELGGLMTPEQSVRPMIDVIQNKGSQHSGTFWTWEDKPYPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9B4</accession>
    <name>A0A6A6P9B4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_163485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9B4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="16648" checksum="635281C278A12912" modified="2020-06-17" version="1">MGAGAPGTRLGGAHHVRGRGRDLYFRTAAPNLNSDTPAPIDRDRKQQLRVRLAFSPTTFGTLPHARLATPLFLAGVARLHLYVCNSSLLHFFPFPSYRAPYSIARDLLIPGPEPPTRFVCPVELRDAPNRARPRLLGAPATSQPSFPHQAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9F9</accession>
    <name>A0A6A6P9F9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_377264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9F9"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052779">
        <property type="entry name" value="WDR62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589:SF1">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="224"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="624"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="815"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="815"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1059" mass="113058" checksum="AB7D41C0B46D36BF" modified="2020-06-17" version="1" fragment="single">MSLGTPSHPRLSTPSAGGLRLTPSNSPYPKTLAARSPVKLAAAGTAASSASLSSRDARPELALALRRVIGTTAGSANAFASLPSEGAFAFTAGAAAVVASVDETTRHVSQRFYRARPTAAPVNPSSSVYGLSTPSNSSLDVRSRAANGMRDAGAGISPFGSPAPDWVDSPSRAWTARERIKAATCVSFSPDGKFLAVGETGYKPRVLIFSAGRDDPADTPLSCLSDHTFGVRCVAFSPDSQYLASLGSANDGFLYIWNVNNRTGAATLYASNKCTSNIYQMAWLGTSLVVVGTRHVKVWRVEGSSPAKPAPSPKPRQSDIGFALASPGHKTLPGRNCLLGALLESTFTSVAAIGQNKGVIGTDRGDLCVLDDSDGTQRISKVADTGFGITALSYDGKGCVHVAGVDGSLTKYKLEDILSAQTPPPSPSPKIDRPSSRQGKKPTHTVAIECLGNLLAAVDSRRSIQLLDMDSRTCPLAVVQKLPAHGTAVQGVRSLFRPNPFDASFYTWSSGGTVLFWAQDGICKGEISIELEQAGGTDEDPNELRTVRNSSRVGFLVSGDKYGVLRIIDAESRSCVYNIKAHASEITDIAIHEGSQTLIACCGRDRTVQIFFKKGSSWDLLQTLDEHVGAVNGILFSSDGNRLLSSSSDRTVVVREAISREIDGESLSAFIILRTITLKASPVSMALDSESENDLILSTIDRFVQRYDLRNGHLISGFKASDPDGGDAVVLSSLVQVPMGKGSPIIAGVSSTDKSIRLYDDAGTLLGRDWGHTEGVSDIALVSTKVAESDPDTVTRSLVTVAVDGTIFMWDVDSKTQQSPAEVTKSTELSGANPTPKDSILTRPPLRRVLSQSELARFQRSPGDESEVTTPTGSRSPRLRKRPSKFTLAQTPKLEPSPMLRRRGSFQAPSSSAFERKSYRNRSPSPPSPRNVQQPPKSRRHEVEARGTRSKGGEFGSLLNSTEQVCRTLRSYRKKLVTSSDALGVQSLRELERELGLTARALGEKAKSKGVDEAIMAKMLDQYSERLVEMLDEKIAATVARQVRQNSEYSEGGTGSVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H3</accession>
    <name>A0A6A6P9H3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_335762</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H3"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor SLU7" evidence="9">
        <location>
            <begin position="118"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="421"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="477" mass="54082" checksum="FE0D1815DA44E26C" modified="2020-06-17" version="1">MPPPSRKPADVSAANKERNEYIPSFIAKKPFYVDDQSSDADYLEHQRLQKSSTDSQSKWYDRGRKAAPAATKYRKGACENCGAMTHKTKECLSRPRKLGAKWTGKDIQADEVIQDVQLGWEAKRDRWNGYDATEYEDVVKEYNELEELKRLAKEKAGGSDEDGADDDADDQAVDKDEGAKYEEEADMGRQQSTSTRNLRIREDRAKYLLNLDLDSAKYDPKTRSMVDSGATSDNAAALVAEEGFVRKSGDAAEFERAQRYAWESQQRGDKNKVHLQANPTSGEFLRKKEQEEADAKRQAHRKALLEKYGGEEHMQAAPPHDVAVTESERYVEYDERGGIKGAPKTKAKSKYSEDVFNNNHTSVWGSWWSDFKWGYACCHSTVKNSYCTGEAGKQAFEESNRLRTAADVERGTNMEVVVKDEEPPVKTAGPSHQEQKKRTFQEMQMGVTEEEMDEYRKKRTAANDPMANMLSKSEVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Y6</accession>
    <name>A0A6A6P9Y6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Y6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="90" mass="10041" checksum="D6FE147CE644AFA5" modified="2020-06-17" version="1">MLASLSRQASRHNPSRSLLACRPFVRSSRLHFGDPANSGCTALRNGGASRSLHSAEMNEADLASLRVDNKRLMRTLHYTCQWGMGKRWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAT4</accession>
    <name>A0A6A6PAT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endosomal peripheral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_279340</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="294853at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="7">
        <location>
            <begin position="5"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="5">
        <location>
            <begin position="200"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="6">
        <location>
            <begin position="1024"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="495"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="931"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="513"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="935"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1749" mass="190711" checksum="082C28FCCB72D6BD" modified="2020-06-17" version="1">MTAHILASELTNLIHESKRRNLDLRNAAEKSLQDLKGLPSTSENQLATDLARRPNFISPFLIACGTKSARFAVPGVACLQRLAVSQALPKERLLDVVEAFRESSSQGMDVQLKILQALLPLLQNYSNELRGELLSTLLHICSVLQGIKNPAVGSTAAATLQQLIIFVFDRLLYEDRKSLQVPTIAEVPSENGPIHIRPAAYDAYKVFYDLCTILDEGKPQWIRFSSISQASVLELIEAVLKSHSNTFLSHPEQINILRTLIMPHVIKSLSERHSFVITLRVVRVLCTLLQTSLSVMPSECEVALSLLNHMLEPDAAAPWKRALCLEVFKSIYADSNLMLKVYAFYDHQEGKKAILRDNLSIFVRLSAEKPAVIGLGQHSADLVPSSFNKDTSAEHAALIEAGGVAGAIAGGTPAHSNMNLRGGSGASLASGPGLSVQWSTVKTPCLEQLDKPDPPSFPETYTYTLVLACMTHLSESLARFILPFTVHYGESKNKKKAKTQEANFEDNDLPELGISGPPEPESSAAPSGGIGRSQSFRKRTVPVNPLTLESHSSYGSIKVVATMIDECWPAVLATYSTFLYATLDADYFRSLVRSFQKFTQVAGLLRLSTARDALLTTLGKSAVPANVLAATSTTTPMTATLDNSPSVLAHAKGLLTADGGTSQEKGHRRTAAESENLSLTPRNLLCLRALINLAIALGPTLGSSWSIVLETLQQADIILSASTATNSKISSITRDRRIGIPQAGSPQEAGNEKASFSMGSEVSAAYSAASRLFESTADFPNDSFLQVLKSLCDMLHERPFPSNPRPSETQAPLLAKHQRRVGSFSGLSVNTRSEGQDYMFALGKVGDLASLNMSRLVSYPPAESGWDTLVRELISMATRKYLPRSPRLMSAEILGRIARDTAAATVSVNVEQRNQSQQRLLSALQSEIEALRSPGKQQSQEGSIGQQATGDFDTDGEIHVIALESLKAILEECGELLTAGWEAVFSIIQSVFIQGDETTQSGNPRVQSTLGRSSFGSLQLICSDFLGTVPDRSMPTLVEILYQFCCQAQDLNMSLTTITFFWNVSDFLHSVMDAASLEEITADIGEHVTDDGLATFKISGDRESSASTLWLVLLLRLTSVTTDGRAEVRNGSLHTIIRILDNSGERLSPCSWQMCFVVIIFRMFSSNCERQTTLRQLPGTDVSADDLRSWNETTKALLAGAGNLLGTYLDTIVQNSRFPQLWDQLLKFMANLLSCQSHALNTATYTALADILSKVEDPKKVGSWTVSHASTLWTANFPIAAATKGSHLLDDGSSTSSQEAYMAYVRAFQEIYRLTKDSPGEAVITTMVENLTRCIFTPDGSSAASYGIGDVDRMTPLQKQIIVSLESIRTEPPMVPSVVVKALSQLVRLPYGDSQKSSLSKLSRTSPTYVALSKASMELLERLIVKHVNDDTSGLLASNGGAYQLALESLSLVISMKYRWKVEGKSTPPWMDATSVALTVLGCGLPCIDSLPPQHRERMSVIWEQVVAIASGIATADLQFASETSSSALYADETFDLHSFTKLHFLMIPRLGASSIPDSIRRSYTSHIFQNSIIHKLQSGEEACVEGREPLRGIYVVRLGRTQDPPPSPRERMAYKCFSLLIELVSFGSTDRSSSVEHVRIAQAAAPYLILRAATVVKAYIADQPLRGRRMPQPESQRQELLFVLREMRKLESEPMAIPDAPGVKVPTKKHLHRLLPLLSKAIKISSSDLEVLGELENIVGTIGDGFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB50</accession>
    <name>A0A6A6PB50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_376902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB50"/>
    <dbReference type="OrthoDB" id="4128781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="107"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="21616" checksum="A9674881E66C20E2" modified="2020-06-17" version="1">MSLPGEHSKSEWVDGSNLTTIPELHSKLGMKPSHHHNPELIHEEEEILQHYKDWIAFNTKEFTNKSKGKDFYDLPDVMYFDMMKQTPRGHFGHHFDHIDPYYDDAHLAYKDLEIVATSKDSGYATAVQRYYGTGTDGREFSFTCRITSLLKKVEGRWKWVHEHVSFPVDLSTKMGDYTCGTGTSGKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB95</accession>
    <name>A0A6A6PB95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_137137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB95"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="219" mass="24818" checksum="26E1AABC9169CAE8" modified="2020-06-17" version="1">MTMGLPPASAPPPPVFAAHPQRSAFSPRSTESRTQRRTLLVAPLVCQPSLRVSPGRRCSLARGRPYNLSAGSKLPLLRRPALSPTRTLPRAVCLCVVATHYLRLWRRYLPRSYRRQFHWIGRHFRPPFHIKPRESLDRYSKSSKLGRFSHQLCSMINSTIRSVPWRRLVTGGRAECRVGAPLIINLGRRLTPNGGREACSATSYIRDFFSKKSHTIVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBA4</accession>
    <name>A0A6A6PBA4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_369107</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBA4"/>
    <dbReference type="OrthoDB" id="420884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="120"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="147"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="509" mass="57907" checksum="BE26C8C993BF1FF1" modified="2020-06-17" version="1">MVISGHPDAHFSEFYAQLDKNAQERLEAHERAIALASQNHEQVRNSAEQSAELYRLHVQREWAKQRDDQERALQQARLDAAREQLERERERQLNEQRIEQQRREAEELARRIEQERLEAEERWRREQQETRRREQAEAERQRKEQEQAAAAARAQAQAQAQARVQTQPAQPAPAPITSSPAAAKPAAGAGPAQIANLDQRNALHKRYLELHKKLKDFRKFMLDLAKMDPAVKGRMGDMRREIKMRVGQLTTDNTKNTERREKIIAVLEEAKTRFPEPAVAAQQFMVSSNLPAGGPQVPALLVYQLHMFAKAVLNQFKEEAGIDTKLAGPVGILASYVFSDPRFKWQGHSFSDILLAKLHKGCPVLFGIYGNEKTEQGRQRLGWPREGGSWASEQRHQDTMSGYGAGYAALSLRIYRSARTNPFPPRMFWQTLALIVNTPARDITETHYIVLKAMVEHSIPSFARIFDTVGLYALRSALVDFASRKPGSTAAQSLGVLREVVNRDEKFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBB4</accession>
    <name>A0A6A6PBB4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxamine phosphate oxidase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_403174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBB4"/>
    <dbReference type="OrthoDB" id="539398at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF1">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="29969" checksum="AAD8B858D6DBEF8A" modified="2020-06-17" version="1">MVKFYPSIPDDLRDWCLRQPVFFTASAPLAGQHINCSPKGYPHRSLRFLGPNRVAYLDATGSGCETIAHMYENGRLTLMFCSFGPAPRIARFFCRHGRVVELGSAEFDSWRGVFGGSGGGGDDDDDDVLVGARAVIVLDVFKAQTSCGFGVPLVDKETDGKEATTTTTTTTAAGPRDTLARWATKMLEKDALDGYRRDNNWRSLDGLPGLRAGRRARGQWVAVEDGGARARRLARQWDAVLVGVLLAGVLLVALVVGGVVRVEMGPMAGGRLRSPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBC7</accession>
    <name>A0A6A6PBC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="10">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="9">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_383885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="9"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBC7"/>
    <dbReference type="OrthoDB" id="5322683at2759"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000006">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000005">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="11">
        <location>
            <begin position="55"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="551" mass="58836" checksum="680FDF0A9854430E" modified="2020-06-17" version="1">MATFKVPSINNEPNLHYAKGSPDRQKLADAMSSFRKTLPVKIPLFVGGKEVTTQSTQTQFDPSNHSTVVAECADASASDVGAAIDSALAARPSWESMPFADRAAIFLKAADLISSKYRFDVMAATMIGQGKNAWQAEIDSAAELCDFLRFNVRYAEELYGQQPVHNSPGVWNRVEYRALEGFVYAVTPFNFTAIGGNLPAAPALMGNVVLWKPSPSALASNHLVLRILLEAGLPPDVIQFVPGDAETVTAAALGHKNFAALHYTGSTAVFRHLYGEIGKGVAEARYAGYPRVVAETGGKNFHLVHRSADVQGAVVNTVRAAFEFAGQKCSACSRAYVARSLWPEFKQKLVREVEAIKVGPPDDFANFVGPVIHKAAFERLSAVIDDAKADQQLELLVGGAYDGSKGYFVRPTVYATTDPAHPLLSRELFGPVVVVYVYDDERGGSAEAAFADACALVDATSAYGLTGAVFARDRAAVRAAEDALRHAAGNFYINAKCTGAVVGQQPFGGARASGTNDKAGSANLLSRFVSMRAVKEEFVPPAGVEYPSNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBS4</accession>
    <name>A0A6A6PBS4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chorismate synthase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_296496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBS4"/>
    <dbReference type="OrthoDB" id="4218123at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470:SF1">
        <property type="entry name" value="CHORISMATE SYNTHASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="42442" checksum="2B92C5B2C5A01102" modified="2020-06-17" version="1">MMSLKTIGSLLLTFGPLVIPRLLAWYRSLSSNRAYNIPIRPPPRHVKRALNILTISAIIALLTTLPFQPFTPENVITVTHSRLQTPTATIFNRLEFLRALTPLDHALRDKLTNLESRLLYLTYGPDVLATCPFCTSTDPRSYFYYAIPSLLFPHVLHLVVLGVVTSAPLSGSEGARLRVPATIAGVALATLELLVAGTYDARAANAGPAKSVADGGGGDAFFWRARLARGLAVGAADALVGLFLYQTATNRWLAEPPSLPERVEGATRALEAANAKLGYAGAVRNAVVRDKGLREAFERYWLEEHRVMGEVREEREVVEGVRSALTRVDIGDVERKAEEWVGGIFGRQRGQSSGGVRVGSPGVASGSDMWAGGSRWRAARGASANCESDEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCZ8</accession>
    <name>A0A6A6PCZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HotDog domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_1721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCZ8"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF3">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G03960)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="95"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="22117" checksum="D8ABD6223E8DFE7F" modified="2020-06-17" version="1">MPPPTCPDEEYFRAIPWCAAVLSSPSTYPEPFPSREYKPATTEDALFGTTLRTSKTIAALLGIRQRRRPADTSDEAVLVALAALGSGLNGFPHMCHGGAVATLLDEVTGAVVGINQEQEKKRLKEGVVSAAERWWTAGSFVTAYLNVKYKRPVRTPQVVLLEARLVDRGERKCKIETQVRDKDGTVLAESDGMFVRLKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD10</accession>
    <name>A0A6A6PD10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_2593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD10"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025664598" evidence="2">
        <location>
            <begin position="18"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="497" mass="49290" checksum="B14E8A9DF35A837A" modified="2020-06-17" version="1">MRSAFTVLVALAGTALAGYGGDHDGGDWGWPHGGHHGNWSHPAWTSTTEMTTYVTTTTCPITFTSSSSIVTSLTTSCITVTSCKHGWCTPTTSSTPTPSSSSSPCPESSSSSSTPPPPPPPPSNTTTPCPESSTTAHPPPPPPPSSSTPCPESSSSSSSPPPPPPPPSSTSTPCPESSTTAHPPPPPPPSSSTPCPESSSSSPPPPPPPSSSHPPPPPPPSSSTPCPESSSTPGGPVQPSSSSPPPPPPPSSTPCSTYTKTTTTTTTYTTTCPVTTTYTSTGVTYTTTYITTTTTESPCPTTIIVTETAPPSPPETETTVISIPPETETTVISLPPETTVVSIPPGSPAPPETTTVISVPPGSPPHSPPPPETETTVISLPPSNPSYSPPPASTTVIPVPPGSSSYIPPPASSAPPPAPPSSSSSPLSSPPPSSSSPLSSAPPASSSTEGGATAPPEETSEAPAPTATEFPGVANGRNVRKSMGALVAGAAALVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD12</accession>
    <name>A0A6A6PD12_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_329529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD12"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="318" mass="35385" checksum="1D28A92E5B60C042" modified="2020-06-17" version="1">MGNKTRRGTDKAALGKGRSEEPAKKSVPVPANKRKDSSASNALKTAKSVNDTRHGPELVLIQVASEPVENPRIHDLFTVPAKLIRRFTKHDVHAAPGNKTSMENWTLSREKAAGTPAPRAIWEVVQWMTENKSAQFPADLELPRDFPLDRLVKVLGACYLLELKGVFVPRALRRRILDHIDTTPMTAAEFKVVCESLPLSDGVVKHAVHKCAEFAVTKEMPTEDVKGIAGYLGELETTEPEFAAWADGVAQKQRAWVEGKNRAAEKEERRKLNAAQKQKRLRAQEETRKGFEHGLALAKDGRRILNDKEVDALMSKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD55</accession>
    <name>A0A6A6PD55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_359854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD55"/>
    <dbReference type="OrthoDB" id="3254104at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="464" mass="49701" checksum="2B1A225465257655" modified="2020-06-17" version="1">MRFRPRSYRASHSWDYNTEQDVVWYWRFIALLASWMILGGYLIFPATYDTDPRLRFSRAVLSVFIVVLLVAGYAFTALLVFALPRHLAFHTESVFLPALTSSALGLLTVFYAFASSTRFDWTTGAVLQTALAAFSTLVYAVLLLFTQRRRARKLAHARASYEAVLASQTGGAGSVSVPLSATSPRSSAHLLGFYPPRQSGSGARGGGDCTPTGPTSPVPWHSATSLGSSGAAERGPLSLSRESSLYNNPNNTSASSGGGGGGVGSRLLRWSNTNSGGPSRSHSYRHSTGAIASSASGGATTPTRSTSTLGAASSAATDEPSSSLADPRRAAAHRAWLANQHPASLHTPAHAPPPLTDEERINAQMASLLRNGARDCGPSPDAGSSTFRIEWPGAGDSEGEGEDEGETDEERAARRRKFAAAGETRERGRSRGLAVEGMEEERARRVREASREERRREIEMGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD98</accession>
    <name>A0A6A6PD98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_330142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD98"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="317" mass="36531" checksum="205D0635075BE149" modified="2020-06-17" version="1">MERAAEISVERLSGALTNAVYVVSPPKNLPPRTESANSASGETNQTPAPAPVKPPNKLLLRIYGPQVEHLIDRDAELQILQRLARKNIGPRLLGTFKNGRFEEFFHARALNPADLRNPDISRQIAKRMRELHEGIELLPEERERGPYVWQNWDKWVERCEKVITYVDRKTREENRRRAEQANGVPYRKREFVCGVEWTFFKETVDKYRAWLDEKYGGPDRLRDRLVFAHNDTQYGNILRLVPAGESPLLLPANQHKRLIVIDFEYANANMPGLEFANHFVSCVPFKPPSLPPSLPPTHSPRISHAFLLHGERRGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDL5</accession>
    <name>A0A6A6PDL5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_368203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDL5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="60" mass="6761" checksum="770C29A9358E8DAF" modified="2020-06-17" version="1">MPPVWNSTFFPAPTNISTNHYYYYSRQTTAQPPTTTIKMYATEIEVPDRNQGSGAACIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDT3</accession>
    <name>A0A6A6PDT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_359945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDT3"/>
    <dbReference type="OrthoDB" id="5308957at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="34"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="524" mass="59905" checksum="C8A7BFAF7E4DFA31" modified="2020-06-17" version="1">MIFNTSTRFDVMELQFTTVPQGPGAQQCSYPKSPADWETHKATILRLYKFKELPEVMKEMEDQHKFKATINQYKKQFNKWKMQPKRVQTHEYRAMLKLKRSLRREANTEIVFYVHGKEVDPAKLARFEERDRERERKKDGHFNYDTLLSSSDIPDSLTYEFRPPESVPSAKVQRRVSLSAESTASSRVPEERRESRSPVSVSSEQAVEGKGLKSPSLKVLQNAGFSETSYLPTPPNPFFGDSPFFLEPTWSDNFYVCTSIEGKCDAQLASIELVDKLRLLSQSPHSISDLGKHRDALGNVSIPHFCSKCKFLADLCAIRDALLVKDYQPQLAAQMMGYSIHKALISRYCTPALTLPLGSLVGDSLAKMSRYQEAEGILETSLAGLESYYGVENLVTREAAVSLAELYMSRCEFARAEAILRRTFLDMYDHIGHYIGQVDLELPYRAFIEGYFHGKLLPGRYSRPFFECNDSSALEVYLENWWADKREINLVWSAAQVIRRIQEARLHAMPRNVDSAGNTDMFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDZ9</accession>
    <name>A0A6A6PDZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_418031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDZ9"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40257">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40257:SF1">
        <property type="entry name" value="DUF1330 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="28770" checksum="B826F9812BFA93CD" modified="2020-06-17" version="1">MQSTLLCDIYLLRLTQSINDFKVTVTRSALKPLVIGTATEWMLKPHTLSVELVSRPWDIFLLVESSSEGLPAEVKSAIASQWKTSANISSSMTESLMKDNHSLLNPSPDHIPPLTGSLQKPRVIDPDLEVNFTPEIEEWTKSFSATDEGKRPVSMLNLLAYNEGKRDTFLGYIEVFNEAVGAKRGAMGKLFGSVPEDQRESSGGWEDIALVHYPSIWHFADLIASEEYRECDRKYKQGAVKDCGILCITSKRDTSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE66</accession>
    <name>A0A6A6PE66_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE66"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="37459" checksum="F3C85F251A2BF788" modified="2020-06-17" version="1">MASHPEFDQNTGAMEVAKAFEEQVRGKTALVVGVSPQSLGESITLSLASQNPAHLILASRTRSKLEEIADQVKKSGSTARVSILVLDLGSQKDVERAAKEISGLTDRLDIMINNAGLCVVKREFTPEGIELQFGANHIGPFLLTNLLTPLLLRTARSPTTSPGSVRVVNVTSQGHRLCPIRFHDYNFDGKDIPAEERWAEGLPPSLTNGRDGEFYPGFIAYGQSKTANVLFAVELTERLGKEGVMAYAVHPGSIETSLSRNLDTEGQATIANTSTFWKNLDQGGATILVAALDPALSKPNPESVYLSDCQLEPPAPHASDPAAAKRLWDLSEELVGRKFGADKAVSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE76</accession>
    <name>A0A6A6PE76_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_10812</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE76"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="17"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="436" mass="48330" checksum="099DE8686565110A" modified="2020-06-17" version="1">MSNTTSTSQGTPRRRFTAIVVGAGLGGCAAALALHAHGHQVLAVLDKVREFGRLGDSLGLGENAFKLLARWGCDVDEVKAIGNQAPSMQIRRWWDGKVLAVQELMDMAGYIGHRGDYHEIFLKWVKQKGIPIRMGAEVVAYDDSANPSLTLKSGEKMHADIIVASDGIKSLARPLVLGMRDDPVNSGYACFRAFFKPSADLKSNPLCGPLMARDSVNIWIGPDMHVVQNTLRNGDEFNWILTHKDDGDVPESWFQPGDMDEVRRLAADIDPTIREAINATDSCLDWKICYRKPLPTWVSPGAHRIALLGDSCHAHLPTSAQGASQATESAGVLATCLDLVASTDEIPVATRAYEKLRFPRVRASQTNGEDLRDRWHNVLKEFNAGQEIDPEMCKIKNRWLYAYDAEKDARERWNEVSEQVRKELAQGQITPLFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEF7</accession>
    <name>A0A6A6PEF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-NAD kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_330571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEF7"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000005">
        <property type="entry name" value="NAD+ kinase Utr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10330:FF:000025">
        <property type="entry name" value="NAD+ kinase Utr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="610"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="631"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="659" mass="71113" checksum="257C1DF3FED7EA59" modified="2020-06-17" version="1">MDVGIHPLLSPREESSLPSLSSISAQQPQPSPAGGNTVPEFLVSPSDHPAASAADSLSAPKLRGSPSTAAGVSPPALQRGSDIPADLDTVKSAPTTPLPFPGAQDDTPATDSSVGEQLPAPGFGQPLRGNKSFLNHRRNKHKQAASIDSIPRQTIMKALAQRSGAPNLMVPDSINSMLAAKEEDARQSEPITSKRLSAALSELQLNSNGSSSKFAAALASPCFFHKRFDDAVNIEKVLEEIQEDEDMSHSRLMQTATSVREVSKQLQRRPIRRAVRNIMIVTKARDNQLVVLTRELAEWLLTTPRYGSDVGVNVYVDAKLRKSPRFDAKGLLAKDPRFEQMLRYWTPDLCWTSPDKFDLVLTLGGDGTVLFTSWLFQRIVPPILSFSLGSLGFLTNFGFHQYKEQLSCIMGDTGMRVNLRMRFTCTVYRSAPTEADPNAAIEAEQFEVLNELVIDRGPSPYVSNLELYGDNALLTVVQADGCIFSTPTGSTAYSLSAGGSLVHPDIPALLLTPICPHTLSFRPMLLPDTMLLRVAVPRASRATAYCAFDGKGRVELRQGDYVTIAASQYPFPSVLSRPTEWFDSLGRTLRWNTRGAQQKAWDGESSAATAAGAPEQDAKFDIDFGDDDAGADSGVSAGNSSDGGNNSPVKRGLSVIGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEL9</accession>
    <name>A0A6A6PEL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-propionate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_277807</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEL9"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="438"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="594" mass="65709" checksum="D857D5B2322A6139" modified="2020-06-17" version="1">MAPPQVSVLIVGGGPVGLITAYQLAHTLPPHHTIRIVEKHAKTAQDAYGRAITLFPRSAEMLDQLGLADELAQRCFACRSTASYDRFGHAVKGRGWEWMERMGDTRWDFALVLRQKYQEEIFRARLAEKGVLLESQVELVQLAVDEARPVGSYRVTAVLEKRGSSPPEREVVKCKYVVGADGGRSFVRRALNIPFDGSSTEDKWVRIDGVVETDMPSPRCYAAIESPTHGNVLWAALDHGATRIGFAFTAERQRAYANFDEAAAVREAVESVKPFQLRFKQVDWYTVYVVGQRIARRFSAADCVFLAGDACHTHSSGAAQGMNTGLHDAVNLGWKLSLVLRGEAAPELLRTYEAERRPNVEKLIKYDKDISRLMTMQLPEGWTGDLNADPNEVLGRVMAEAATFSSGLGIFYEPDRMLNVRGTFDEPVSDVAAERSPLQPGQRGPDVELKKPGTFDKTSLHKETPNRARFHAIVFAGDPSVTASELHRFSSALRSSRYFSADSVPLSWLVIAATKPQPSMFEALGSTSPIGKAFYDPEKTAHKRYGVVVDKGAVFVLRPDGWIGTAAKLNPESVSELEKYFRNFIISSTSSPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEQ8</accession>
    <name>A0A6A6PEQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_331469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEQ8"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="314" mass="34736" checksum="742D0A99A5FC2228" modified="2020-06-17" version="1">MRVGVIGPTGFGGSYVCVELINRGHNVVGMSRHPEKLGTHPLYTARKIDIENMSIDELAKAFGDVDTLVSEYGPHTQGADALQYMPYLEDIRKIVLAVKEAKVKYFVHVGGTGSLYVPGTEHQCAVDCPDFFIAYRRGIADSHAHVCYMEERLGPMGSALRSYRNARLHAKEGKETEEDKAFVKDYEYKVSKEDKGLKFIRAGRTSFMFFDGNTSFRWTFVSPSALYRPGRRTGKYEVVLDELPLKNTPSASSNPLDGRLLGVSCADLAVAIADDVETQKLVFKHWTVVGDLSDDTPYPSYITLADTTDGKGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL85</accession>
    <name>A0A6A6NL85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_359296</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL85"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="236" mass="25844" checksum="5CF32B4AD168B54E" modified="2020-06-17" version="1">MARFAVRSPDPKRDMDPRALCSRLLALNFVGIHTSAVTIQNFWLDVLGRPGKEELLTALRKEAEEVQAKCGGAWNKANVARLALLDSTLRESLRVSAFKGRGVERQVVAEKGTTLPDGTVLPKGTRLGVATTEVHADCELHGNDANVFRPDRFVGKGGTGGVIVTGESFLAFGLGRHACPGRFLAAHELKLLIAYMLLNYDIAPLRCRPENSSFSDFSAPLNVLLRIRPRRDARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL88</accession>
    <name>A0A6A6NL88_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_158523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL88"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16140" checksum="E81E0F0C41CFB847" modified="2020-06-17" version="1">MDEPAGIRGRRPAAALVGPPSGAGQPVLIQPCATAGLAARCHAPRRPPPDEVSGILSGEEPLGRDRADLARPRRWKTPSRRKAMALPGSRRKEGGGGRRRFVPPSVAARGRTRRKRRREFKAVNSLRLVDLRTQPALAPARCSTPGAAPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLH9</accession>
    <name>A0A6A6NLH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLH9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18288" checksum="5D9BD295C98B0728" modified="2020-06-17" version="1">MGRRDGQVIIIRRDRFTTDVAHFVMLVRGLGAVTFWGRNPGAILRSRIQQANRLHPIGPAVRCSHSAQDFPGPAITPARRADPERNLLGFRNVPALPAAARRFTSRMVAQSAPSICYTGLALRTYLGRYARGLGYQLSSVVPFSFPSSRSLLARDRRRARSSEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM68</accession>
    <name>A0A6A6NM68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_153787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM68"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="181" mass="20524" checksum="D29463F2DB4F5757" modified="2020-06-17" version="1">MRHNQPIPFCTTALQIGRPQFPVYITIKKRLYCASFPFGSLDVQFRNVALPAYAAKTVQPWLPASNPSFINASKRRLGPREIDLGLYFLSRTKNGLGETSLNAWEPDTGFILNAVFIPGFVSPCYSQSLPDYERPRHSQGKVWPGYRLGYRRGLDARLWRFVRSLGPSTRTPDGARAFRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMI2</accession>
    <name>A0A6A6NMI2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_259990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMI2"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="23354" checksum="2E394C5DB95D5300" modified="2020-06-17" version="1" fragment="single">MITRLESRLVTDEELDAEVKTIYTMVRTLERRCMEAISGQPSFPAGRQCENSLNDEQFQAITAMHRAVLDEYGDFFLATQYPRAPPAFKRLPLEYCMPARLWAIGIHGLLEFLRHKLPASEEHIEAFIQVAYQMLAQISDAAPNFECTWKECMGDLARYRMAIESKDCRVKEAWTDTARELYSWCSEQDPAVGRLYHHRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMJ6</accession>
    <name>A0A6A6NMJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_147503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMJ6"/>
    <dbReference type="OrthoDB" id="4738875at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9996" checksum="48150EBE90E9C124" modified="2020-06-17" version="1">MYFGELGDRQVHLLVLTIHRDCQRHSAGAKLRQWGMDISKDLKVPATPFSSPGGQKLYAYMGFEYLGSVTVQTEGENEKLLISAMIHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NML5</accession>
    <name>A0A6A6NML5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dehydrogenase with different specificitie</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_328339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NML5"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000374">
        <property type="entry name" value="3-oxoacyl-(Acyl-carrier-protein) reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="27092" checksum="1FEFEBA6E951903A" modified="2020-06-17" version="1">MGSLQAQDLPLSGKVAIVTGASRGIGVGIALQLAKSGASIAITYTSAKSTPAAEDVAQRIRSLNNGARAMTVRGDLRDPSTPAAIVSAVLDALGPHIDILVNNAGLEVVYPIAELPVSAWDDGIAVNLRAPMLMTQAVLPHLRAPGRIINVSSVGARVGFEAMATYLASKAGLEGLTRGLAAELGPAGGHTVNAVEPGPVESDMLDELPQDLIQWQKNRTPIGHRVGTVEDIGDVVVWLAEERSRWITGQSISASGGFLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMS5</accession>
    <name>A0A6A6NMS5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_294386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMS5"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="13231" checksum="F499B1070E6A967C" modified="2020-06-17" version="1" fragment="single">DYNARKNQLVLRMPTAVHEMFIDGIEDATRNQLKLIRKGSSRVATFAQRVCPARLTDIYLLVEDTLLAKSESKCSPDASFCHDGVLYLGVIIEVLHSQKRMELGRLADSCFLDSDTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMX2</accession>
    <name>A0A6A6NMX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">40S ribosomal protein S9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_357284</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMX2"/>
    <dbReference type="OrthoDB" id="1697570at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000021">
        <property type="entry name" value="40S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="105"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="163"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="22145" checksum="66CAC654E1EDD5A8" modified="2020-06-17" version="1">MPPRVYSKTYKVPRRPYESARLDAELKTVGEYGLRNKREVWRVQLTLSKIRRAARELLTLDEKDPKRLFEGNALIRRLVRVGVLDESRMKLDYVLALKIEDFLERRLQTCVYKLGLAKSIHHARVLIKQRHIRVGKQVVNVPSFIVRLESQKHIDFALTSPFGSGRPGRVRRKKAKAAEKGDEGEGDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNE4</accession>
    <name>A0A6A6NNE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_142601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNE4"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="35071" checksum="15D1A18A1060F241" modified="2020-06-17" version="1">MSTPKYLVTGATGGLGRSVTHHLLSLIPPSSLYITSSSPTPPPSLAPFLSAGANFRSANFNSLESMRSAFADINKVFIVSVNSWDSEMRMRMHFNAVQAAKEAGVEQVWYSSLALGSGSDGKGSGEGDRRVADVMKAHVETETMLKESGVTYTAIREGVYGDAFPTFLGWYPTDPNQTIYLPADGNVPMVPREELGEATAKLMVQGGHENEIVLLTGPKAHSLAAIVDTINKTTGRNVLIRHVNLDEYVMFGTADDEGGKPEAFFRAWSTFYSSIAAGDGSVVDPLMEEVLGRKPTDALEFIAQALKENPNYTWHQNYANRGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPS3</accession>
    <name>A0A6A6NPS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_124127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPS3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="19399" checksum="4EAA8CA30D9D6D75" modified="2020-06-17" version="1">MCDAVELPRPASSRVRQSARLMRRAPNCSGVNLEPCRSPPQRRTLHGRSRAPDGDESRPIAAPLRQRLLIITNPATGCSSPHAMLPRRATSQYRRAVAQHPNPHLCLCAESRARQLLFARKPVARSTARPRTPARVENTRPQSRIREWWPQVALLAGLSSRSWRGRIPASSAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPS7</accession>
    <name>A0A6A6NPS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal binding domain of Ada-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_382201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPS7"/>
    <dbReference type="OrthoDB" id="2447880at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="entry name" value="DNA Methylphosphotriester Repair Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00165">
        <property type="entry name" value="HTH_AraC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="Ada DNA repair protein, N-terminal domain (N-Ada 10)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="6">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="23200" checksum="4D4D76A89D437272" modified="2020-06-17" version="1">MTFHPPTSHTNDAFITDSNRWRALVQRNRAASSSFVYAVRSTNIYCRPTCPSRLARRANIVFYDTAADAEAAGFRACKRCKPGGAADEDPALDQGALVRRACEIVREEAERGETLGCAALAKKVGLSVRYFHGLFKRELGVTPQEYARKVAREVIIQRAGDGGDKEAVAGTEALQHTLPESLDINAPLLGSFDPFQVTAAHGRVQRSIRVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPS9</accession>
    <name>A0A6A6NPS9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="3 15">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 15">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 15">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_327180</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for methylating the 5'-cap structure of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="3 15"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPS9"/>
    <dbReference type="OrthoDB" id="10248867at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 15 16" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="18">
        <location>
            <begin position="156"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="365"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="165"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="16">
        <location>
            <position position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR028762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2453795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="549" mass="61435" checksum="7F57CD976C25C7ED" modified="2020-06-17" version="1">MPSESPPMDPNPKKRRLGTPTSPNPPPSSATASTKTPHRPGSSAAKNQSSPPTKYRASPAEHKTGFAGRPPPQTSRPRSPSPPRSRSRSRSRSPPRKRKRPGATARVGREGAPVGASARREEERREALRARGVHDAVRQHYNNVPQRGKEWRRTDSKIKGLRSFNNWCKSALIQKFAAGYDYGWGAGAPPKPHILVLDIGCGKGGDLQKWQSCPAIVDLYVGLDPAEISIEQARDRYRGMTPRNQHNNNNRRHHQRRLFEGRFLVKDCFGESLDDIPVIREVGFDPTAGPGGAPTRWTGGGGFDVVSMMFCMHYAFESENKARRMLKNVAGALKKGGRFLGVIPNSDVLSEKVEAFHLKLDGAEAGAKAGNSSTNPAEYDSDDDWDPEKSLDVDDEPPPAAAQPPPPPTAHAAEDEKKDKEDGEVEQQNVLEWGNSIYKVRFPGQTPKDGVFRPPFGWKYFYFLEEAVEEVPEYVVPWEAFRALAEDYNLELQYRRPFNEIWEDNKNDRVLGDLSERMGVRDRDRGPLRVTKEELDAASFYHAFCFYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU8</accession>
    <name>A0A6A6NPU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_355150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU8"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF7">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="73"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="234"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="557" mass="61560" checksum="231982360E742141" modified="2020-06-17" version="1">MDWKTQAKLKRESVTALIPKEWILDSIPSPSEQRDVTGDYIRKFLSDEEIEITETDAFEIVQNTSQGTWTAVEVTSAFCHRAAIAHQLTNCLHEIFFDDALSSAKRLDAHFSEHKKPMGPLHGLPISLKDQFHVRGVETTMGYVGWIGTFQGLKGTDKEKVFESEMVRELRQLGAVLFVKTSVPHTLMCGETVNNIIGYTWNPANRFLSSGGSSGGEGALIALRGSPVGFGTDIGGSIRIPAAFNGIFGLKPSSGRLPYEGMANSMDGQNSILSVVGPLATSIRSLRLVTKALLGAEPWMYDPLVLEMPWRVEQEERARDRKLVFGVYRDDGVVRPTPPVRRAIDHTAQRMRDLGHEVIEWTPPPHEDLYPITMKTFFFDGGQDVHSAFGLASETPSEQLLGMIGQEPGPQSTGSEIAAVNVTKREMQKAYLDYWNSTASQTPSKRMVDAIIAPVSQFPAARPNKYGHYGYTIWANLLDLTAVVIPVLRARKDIDVVDAGYKPRNDSDRQAYESYDPEVYDGAHVGLQLVGHRLQEEKMLAIAEYVHGALASGDVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ62</accession>
    <name>A0A6A6NQ62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_366839</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000035">
        <property type="entry name" value="SH3 domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053039">
        <property type="entry name" value="Polarity_Bud-Selection_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="558"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="704"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="747"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="763"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="781"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="804"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="818"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="897"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="959"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1001"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1058"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1119"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1143"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1161"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1182"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1198"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1213"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1269"/>
            <end position="1294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1411" mass="149473" checksum="6DDBDC6BBDFC67A0" modified="2020-06-17" version="1">MTRPQIIRADTLDLQDQGSPSAQDHSRQPARPAPLGVGPAAPHQQGELRHASEERADEQTHLKQNQGTLHEEPEDLDDSEDEVRGRGRSGVNGTMVNGTANGAAANGTSADSNGAAGNQYARDEQAIRQNGGAVEERDADGGESGDDMDDDMMDKISSSPSIDDGGYPLRLPKAAATKPSGPATRTISDRWPKRCSSLTPKPPVFARRGTPSPAQFYPTPPSSASPATRPRSPTPHHELGFRASGAGSLRGVADRDVSREAAADEEPGDDSVDDSSPYLETAAHLPLLYDMRGREPNGAPNGASPSPLPLPPSLARARRERRASPLSVQHGPRPGGISDPDHHHHHEHQQPPRQQLGGGNTGRLKSLMEEAERVLEDLEARDREELAREERARRQRDEDAAAGAGTGALPRDASAATMQTDSSVEPPGEADVFRFQRELSELSSRLQKLRVEDLAKDLLPLDDPLLHDDDDGVDDSGLGTPATPNFDTELRSEFEDESDDADADADAGPDALAVGDAGDEARPRRRVASPTECLIASSEEDEWDEFSMSSLGFDEKDIDFEFVYALHTFVATVEGQANATKGDTMVLLDDSNSYWWLVRVVKDSSIGYLPAEHIETPTERLARLNKHRNIDLSQTMLGDNAEKSKNPLKKAMRRRNAKTVTFSAPTYVEASDYDYSSDEADDDAEALFGGMAPPDSDIVEDDVRERGVQEDDDEITAVEPLRVNGKKDSRAGSVNGTAEGASSERGSVSEDGPRPSSDEVGGRSQTAPKSRNGTVRNTDSFFKDDSVETRKITLTPNLLRDDGSTASSSTASASRSSGDMKERSGSFDLVEKNVGPEKSSKESSDKKKKDRRPGMLSGLFKRSKDKKSKSSDSADSPSTLLEPDSAKTSMSEDRSRNSSPTKGQGLSPNGSGQVSEEVSPTTSDKISPTTTIDSQRNLSPQRQPSKGRLQKQQPTSKFGSASTSSPTASGREEGSSVSSGSSAGTPRIAEPQSATIVNPEVEQKQQRGSSAERKESVNGRDVSPPKREDSKTTPTEEQPKGAPQAQTQQPRSPEKSAPTLSVNTDPFSDPANFTTTITENSHTTDAPPNQNGAPPPRGPALEPDRLSDSPVNISPVDLDRDEDDDFADPDLLRGNLAAANGKPATAPVVSTPPVAQPPGLVRDEGSSPEGTDERDSPVSPVSAEEGAGGAAERSAGEPGAGRAHGGAGNAFVFPPPNRPAPSPSPPKGSPVAAPQLQPQRQTKEGSPASLHPSPTGPAPTGALPKPPTEAAASGAAAGSEPPQHHPQQPQQHQQQPPPSQPQQQPVWSDALLRHYLDDPTEIRDMLVLVRDVSGVAPVRHDDPVVAGYLEEERGKVAELGSALDGLLGGWLERKAASAGAGGGGGGGGGGGGGRMFCIGAPKRLLGLLELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQA8</accession>
    <name>A0A6A6NQA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQA8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="150" mass="16965" checksum="7A5606CCE27B59C8" modified="2020-06-17" version="1">MPFKVRARTATMPLKAVMLTQRRRRDPCVAPHTWFRTGGFARSLVQGTSSELAEFGLGSKSGMGKWANAIESIGPGQMRRLFLARRDSDRATARSSYNWKSWRPCSKMRREILRGEKKKPAGHPAHRLARPRTLAQLMTKKTTIAPDSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQC0</accession>
    <name>A0A6A6NQC0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_114771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQC0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21781" checksum="F2D3469C9020E6EC" modified="2020-06-17" version="1">MDSKPNQGRDEWMRGVGKNWGGGVLGKRVQLASRFRRERERESESLGSGQRAAGRAEPERKRQGARKMRRVRMCYNANALRRRLMRTQGNGEGVLTLMLKPDTCGGVCYGNAAATTPDGRELGFLDGPFARRFGGEEKRSEKGGTGVSGVELRRARALGSRRKLRRRDVRRRFSLYFGFFLGDGRREDARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQW2</accession>
    <name>A0A6A6NQW2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_112758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQW2"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="173"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="352"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="529"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="561"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="592"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="608" mass="67241" checksum="A6DA336BED589062" modified="2020-06-17" version="1">MENPTPSMADQQRSAPSPSSAAPNWPVETGGSSKKLLAVDDGVDDVPLYHAAHAEDDAERKLKKTRKRRRKDESLTATLCAWTVNHQIGISINLMLLLALAHICFPRARRRTRKYFDLSYRDPDTGLYSQGWDDMYFVAFWVVAFTGLRATIMDYVLMPCARLGGVAGKKERLRFAEQAWLLIYYSCFWSLGMYIMYYSKYWLNLREMWTDFPTRSIDGLRKWYYLVQFAFWLQQILVVNIEERRKDYSQMFIHHIITCTLMFTSYGYYQTKVGNVILCIMDFVDILLPAAKLLKYLKFQRACDVAFGVFIVAWFVTRHIIYPLVCWSVYADLPPTVPYGCYDSGTGARFSPPNASSSSPSSSFFANDHSQHQHPHHAHQSHDDTISSFAAGTGAGAGAGAIDDYQNLLATGGTAVLRHMLQPFRDPTGPVCFNVRIQTAFLALLLALQGITLVWFGMIIRVAWTVLKGQGADDSRSDVEDKEDEELELELEEDAVGQGLEGAAAVIREEEVVGAEALDWNGRAERARARARGAGKGRGKGRASGRRAGSGSGSGSGTGVGVQAVASASGSARGYKRAGAASRASGISIPGHGDRKELLGRIGCDKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR92</accession>
    <name>A0A6A6NR92_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_107600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR92"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24746" checksum="518BDFA1FB311034" modified="2020-06-17" version="1">MGSRALPPTHNTCLETHEASPSAKQALTAPILSRSHIAQFIRRRFPTPARVGAGRKAGRRVAAALRRSPCLKRNPAGNELGAFARGENPSACVVTPQTPPTKQREAIQLLLTIDPLRHRCRTSRSSAAAYLLLLYHIRFIFFCLFFFNISCWPRLTATATLLGDQTESRNGQSSTGRDRLHSCSVVCRGGISLPFFSFLFCRLNPLLFPPRPYFCSPFQSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRL8</accession>
    <name>A0A6A6NRL8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_354606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRL8"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="300"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="741" mass="80872" checksum="B8FE6B177ECDC269" modified="2020-06-17" version="1">MHHPHPSPQGPPPPQHLQHSRSGVVQQSHPNSPHPPQPHPPPQGPYASPHHSTSALPQQHQSPYVGGIPGPPHQQLAHQQQQQPQAQTQPQPQQQEVPYYAHPSPYSTGSGSGSYSASEQSELMATAAMNRQYPPPPIYHTPQSNSPASVQSPTQHDQHGRPLYSQAAAPMQQYMQYPPYTMAPGPYPQHPGAQQHPSLPSGSMMQQLSHQPGQPMPPQGSHPHTPGLGSPRSKMTQTPQQRPPSGLGAPQQTPTGPPTGTPNMQHPGTPQGPGGVNANAAPGPIPATTPLVVRQDQNGVQWIAFEYSRDRVKMEYTIRCDVESVNVDELPQEFKTENCVYPRACCHKDQYKGNRLHYETECNTVGWALAQLNPCLRGKRGLIQRAVDSWRNSNQDPRLRSRRVRRMAKMNNRKTAAAQHGSHMGGPSGPGAAGVPNSAGLAAAGPGGPRQPAMSMSGQMHHHHEHPGPGPGGDDVTAPNGQGTASPNDVRQAQNFYPSYPPTQAVGATMPPIHDGMGHTGAHAPARTSTAASLSKEQEEDQNLALFGDVPADKRRKFILVDDAQRGTRVRVKVMLDQVQMQEMPDSYLKSNSVYPRSYFPTQMQSPPPSRHGSRFFDDDDDNEEEGSSGTTPTTGRTLVAVPISDGSDAKVPFPRMSRAKRNKEVTLNNLGYRMSWSQSRVFSGRTLFLQRSLDAYRNKMRNTMVARGQDVTTVAPHFETRVGKRKWLERSKKAKGDSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRN2</accession>
    <name>A0A6A6NRN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRN2"/>
    <dbReference type="OrthoDB" id="302966at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="408" mass="43255" checksum="D34FE1C5424F8D46" modified="2020-06-17" version="1">MTTSTAALAPPSRLDPFIHALSRVYGPAVLGPSHLDSPPSAWTPPPAAAGHRGRYLWTDAFGVLDLLTLDREAGAAPGPGPGPGSSSPHHRHYYLDLAARVVAAVHETLGRTRDGARRLGGASAAAPLAGGLRIGKEAGEGAAMDADGQYFHYLALWGFALNRVGAAMAGAGRGRDEAARFNGLGVQLMGAVHEWFFVGGSREAGRPRMVWKVAVEGGRVLVPSEGNLDPVDGYVVCRLLRAGARRWAGDEGDVLGKEIGDFEAVMRRKGEQRVSEDPLDLGMGLWAAHWFEGREEWATALVRRAKDKAVRLHRAGYFAQPLRARLAFRDFGAALGIGCVAGSDSGEGDEEAPLRACAADVLAKWRDALEGPLTPGDLRPISDVMYAAALVPGAFKKGYFGPEAVDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS14</accession>
    <name>A0A6A6NS14_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS14"/>
    <dbReference type="OrthoDB" id="5371646at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="293" mass="31095" checksum="9A0625DD481603E0" modified="2020-06-17" version="1">MAGGPRPPQGFSPHPGPMMLPAMPQPHQEIPLKRPHPHEPLTPLGAPGRTLVPRPPQSSQYPMHHVYQSSPPAEQQPPRKKRGRPTKAEAEARLKAAQDRGEVYPPLRSKAPVERSFVTPEGQTRASPAMGTTSIMSTPQMTPSDVPPESSGPRRPSRPSTSEGSGLTQIQAFERPEGGAGFEPQSRSGSTGRPEEQRVPPYVQPTPSPGVPAPAPAPEPPREEREGRMEEREERPPSTSTPGPPTTTTAAGQSAPQSATTAATATQPPTTTTTSSATTTAPSTRSFKETVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSZ0</accession>
    <name>A0A6A6NSZ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase phosphorylation protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_308791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSZ0"/>
    <dbReference type="OrthoDB" id="5390672at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019315">
        <property type="entry name" value="MMTA2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039207">
        <property type="entry name" value="MMTAG2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580:SF0">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10159">
        <property type="entry name" value="MMtag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Multiple myeloma tumor-associated protein 2-like N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="33778" checksum="D0D158B236754499" modified="2020-06-17" version="1">MDLLQTVRKEGSRGGRADFKWDDVKDDKHRENYLGHSLMAPVGRWQKGRDLTWYSKSKGDGNDEDLAAARAAELAAVKRAEEDAMAAALGLPVPRRGPSNPNLAPLGERDVKKVLQHASAPAGEDDGGEHGGRGLGYGHYDGMKGAEGERETLAGVGLGGGDAAAKKERRRIHGRRSRSRSRDVERKAKRSDRDRDRDRRRDRDLARDRDRSRTRRYERYYGDRSHSRDRDYRSRRNRSRSRNRDGERRPRERDARFDRSPSADRRKDRYSRRPRDSYDAPRSRSPRERRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT15</accession>
    <name>A0A6A6NT15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_387441</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT15"/>
    <dbReference type="OrthoDB" id="21557at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051078">
        <property type="entry name" value="SGF11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367:SF1">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="179"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="267"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2454647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="402" mass="42760" checksum="8FE8E709EFBBAC54" modified="2020-06-17" version="1">MSEDSVDAEGGASKSGKSGLKISGASFADLASNIIDSCIYNIIHDTTLAEQRAEKTLRAQSAATRATETALAQLANSSSDAPSASGKNALSNLPSGRVEADGAVYDGGRVCLRGNPLVTVPEITCPRCKLPRLHYPITGVGARQPDVTKQYCTRHPFVSRPGYDIYGNPFPTDMAKTKKERELLRQQQRADKDGTPNSQDTGTPPDKENMGSKNNSLSTGGKPASYIPWHTCPNCKRSLLITRFAQHLEKCLGISGRQSSRNAMAKLNGSISGTGTGNGATPLGSRVGTPVPSGLTAKDKKGAADDEAAGEEKDTPKKVKKKSSYIKKADREKMEKEGKPTPKPLGRPPKKSQPQASEGNEKGKRDRDEGEAEVPRKKLKISREGSGAKKADDDNASIRSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTP1</accession>
    <name>A0A6A6NTP1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_373592</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTP1"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="33508" checksum="C881C26E4218E32F" modified="2020-06-17" version="1">MSLPAARRLARRPQRLPSAFPCAAAAVPADCLPLRLLCTTGGASASAASARTTSSRSPGSPSLSSAPASAPASPLTSARRAFSTAAARLTRHRGPRGDRNANRGVSALRRTGLRPRQTLSVGKDGLPTPVFDAGKRARPEGDEDHGLWGFFGERRKCILTPEEMNAFGREWTVEELRRKSWEDLHGLWWVCARERNRIKTDSAERQRLQAGYGQFEADERYKTALRTQKNIRNALIERWYAWGSARQAARDDPEIVMYARKGEPAYKPSTSYEPEEAEDVEVKAEEVAPSQERKPQDQQPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU32</accession>
    <name>A0A6A6NU32_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3431 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_290462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU32"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021838">
        <property type="entry name" value="DUF3431"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490:SF3">
        <property type="entry name" value="DUF3431 DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11913">
        <property type="entry name" value="DUF3431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="30004" checksum="09BC0A82D6BF8570" modified="2020-06-17" version="1">MEERRKTIVVASMKKEDTSWLSKRLLDWDKKIYIVDDPSAELTVPLNKGHEAMVYLTYIIDHYDSLPPYMVFIHAQRYQWHNDDPVYDLHYPLLHLQLPHVEEHGYANLRCTWLLGCPAEIYPKKQASLHPYRSYNLDGNITSYEAYLHAFRELFPGKKEPDEIGVSCCAQFAVTKEKVRERKRAEYERYRNWLLETPLPDDVSGRILEYSWHMIFGKPPVYCPNAPECYCKMYGLCGLNCPTERSCVGRYNLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUA1</accession>
    <name>A0A6A6NUA1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Muts domain V-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_373418</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of msh2 and msh6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUA1"/>
    <dbReference type="OrthoDB" id="295033at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000003">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000523">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000015">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000017">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="12">
        <location>
            <begin position="729"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="866"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00064337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="934" mass="104317" checksum="5C05A78667F25DD8" modified="2020-06-17" version="1">MASRPELKVDDEVGFIRFFRNLSTKGDDTIRMFDRGDYYTSHGADATFIAKTVYRTTSVLRQLGREPGLESVTLSVTVFRNFLREALFRLGKRIEIWEASGRNNWKMAKQASPGNLQAIEDDLGGQLEAAPIILAVKVSARASEARNVGVCFADASVRELGVAEFLDNDLYSNFESLLIQLGVRECLVQVESAKGDVELAKLRAIADSCGCAVAERSGGDFATRDIEQDLSRLLRDDKGGAGLLPQTDLKLAMGSAAALIKYLGVMSDASNFGQYQLYQHDLSQYMKLDAAALKALNLMPGPRDGSKTMSIYGLLNHCKTPVGSRLLAQWLKQPLMNVKEIERRQQLVEAFVEDTELRQTMQEEHLRSIPDLYRLAKKFQRKKANLEDVVRAYQVAIRLPGFLGTLEGVMDEKYKDALDAEYTIKIREFSDSLSKLQEMVETTVDLDALDNHEFIIKPEFDDSLRIIRKRLDKLRYEMSLEHRKVGRDLDQDTEKKLFLENHRVHGWCLRLTRTEAGCIRNKKQYQECSTQKNGVFFTTSDLQSLRREFDQLSENYNRTQTGLVSEVVGVASSYCPVFERLAGVLAHLDVIVSFAHVSVHAPTAYARPLVHQRGTGRTVLKEARHPCMEMQDDVQFITNDAVLERGSSEFLIITGPNMGGKSTYIRQIGVIALLAQVGCFVPCAEAELTIFDSILARVGASDSQLKGVSTFMAEMLETANILKSATRESLIVIDELGRGTSTYDGFGLAWAISEHIVREIGAFALFATHFHELTALSDAYPQVKNLHVAAHISDIEQQVTGKGGAQAAAGERRREVTLLYKVEPGICDQSFGIHVAELVRFPEKVVRMAKRKADELEDFSGKGEAAQEDTLPEASAEEVEEGSALLKGILQKWKREVEGKPGMSKTEQVERMRELVKGEKRLAGNPFFKRLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUY5</accession>
    <name>A0A6A6NUY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_387068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUY5"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="93"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="362" mass="38938" checksum="D8E09E264A1748B8" modified="2020-06-17" version="1">MSAPQEQPAVNGKAAASDGGSSSRPTHGGGRDPNAIVKVEPYRKGDLQPSYAAVLNTDTEDAGSHGWYGGMINTLGACIGTLGAIPCCIVCPNPYRPVGQGNVGLVTKFGRFSRAVDPGLVKINPLSENLIQVDVKIQIVEVPRQVCMTKDNVSVNLTSVIYYRVVSPHKAAFGISNIRQALIERTQTTLRHVLGARVLQDVIERREEIAHSIREIIEETAGGWGVEVESMLIKDIIFSDELQESLSMAAQSKRTGEAKVIAARAEVESAKLMRQAADILSSAPAMQIRYLEAMQAMAKTANSKVIFLPAQNQTVQQALSQAENAGEGPSRYSQPNSGAEGEYGHHNQGFQSAVNARMVENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV24</accession>
    <name>A0A6A6NV24_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Cytochrome c oxidase subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Cytochrome c oxidase polypeptide VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_349895</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV24"/>
    <dbReference type="OrthoDB" id="5778907at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00923">
        <property type="entry name" value="Cyt_c_Oxidase_Va"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.40:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0349">Heme</keyword>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00070174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00082700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="18015" checksum="FDF35AFF50F80C91" modified="2020-06-17" version="1">MSSVALLRTALRVTSVSLRPPVYHCARETRVSARLPAAAPRFGFSSSAVRKADDHEESFEEFTARYEKEFEQVQDVFELQRNLNNAFAYDLVPSPSVITAALRAARRVNDFPTAVRIFEGIKAKVENQGQYDEYLKELEPLREELGINLKESMYPDGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWD5</accession>
    <name>A0A6A6NWD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_55005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWD5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="9072" checksum="EB291C17C2DED714" modified="2020-06-17" version="1">MKETERTRPQNLLGGCRPRRWKLPSGQSAISVDAGKPRQQPASPAIFRGEGSHRTQRFKKTTRADRRRNLAFVSRTRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWQ5</accession>
    <name>A0A6A6NWQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_364941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWQ5"/>
    <dbReference type="OrthoDB" id="1936594at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044244">
        <property type="entry name" value="TTC27/Emw1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="704"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="738"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="315"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="486"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="787"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="519"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="788"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1110" mass="116420" checksum="FBFD4E0F2FFE220B" modified="2020-06-17" version="1">MTDPLHTLYASTLPPALASSPTLSAQLAALLNGDYHALLSSPFARQLLGLSADTDTSTDSDNVKTTAPSPSAWLASLRTRARARAASTTTPTDPHSALLVALAAHATFLQSNLTGPVLPFRPGPLLLPPRVAQDARRLAAFRRGLVRELCADGVSAYALTPDVEAFCAAEAVLGSVCEGLPAPEGGTEAEAGDEGRGGFETAARWARLRALFTHQKLLAEAAPGLQRDIYAALDGLDPRVLEPGSGVETDGRVAYLLERAAIHTFHGLDARAREDVDAAAKLRRFEFVLTGLLGKRTRFQEKETSQLVVLARSYEKEEGDDEVDGGGNEAERAANGDEKGKDERAETARPGTFDLNDDTLLESISFTSQNAGGASSSDLPGASSSTIPPALASLDPAAQPRLHPLDAAILLAHASAITNTNPTHGLTREQTAPFATRVIEGGSANWQVYTQALLVRSRVEGYSARTAERGLLQLQALVDQVVTDTASAASTEPTDANTTSEADATKAEASPLAITTINADASSPDSSSTAAAATTFLPRPKSATESAPAQARLAYAPALASPLRWTLEAELAARWVALGGLRSALAIYARLRLWGECALCWAATGREDRARRVVRRLLFVPGGPEEAKSRANTAEEGDVDVGADFNVDGDVDAEAEAEAEPLADGPERDPLPPDAPRLFCILGDLDRAPAMYERAWAVSGGRYARAQRSLGRLRFAERDFAAAAAAYAKSLAVNQTNGAAWFALGCALLEMGAWGRAAEAFGRCVQLDDGDAEAWSNLGTALLRMGMEDEGAGGDDDDGDEKERAEAASGAPAVRLADGSDEGQGGENEDVAEDNTTTMKKKKTPAALRADALRALLRAAHLKHDDARIWDNVLTVAASTTPPSYAAVVRAQTRLIELRGGASSSAAAGRVNGGSGGAAMAAGEAVVDADILDRLVRHVITETAEPDSGGGRAAVARPGLPRLVDELVERGVAPVVTGSRRLWRAVARLRVWKGEPAAALAAEEKGWRAAVYGAGGAKWEAGLAGEGAWDEVVEATVELAEAYESLGGRTREGGEAEGEGAAGPLLVAPDWRFKARSAVRGVMGRGKECWEGSAGWERLRECLDGLKGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWT8</accession>
    <name>A0A6A6NWT8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWT8"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="154"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="38655" checksum="7D1A1D4C8AE12CA9" modified="2020-06-17" version="1">MVAVQASQLLEAQRDADAEERAAERDGWFRVTNITDLKIYPRRFFEGDGDEFEKRLTERLTERGRDFVALEGTCVRYYDGLAKQMKEPPLDYYRRDMAEWAAVWLPYKESGRVVIDRKTFQDDNHLSQVAIKPNSNALEKILYSLDDQIQQKGKGLVVLLHGTPGSGKTLTAECAAEITQKTFLTASLAQALRYASIWKAAILLDEADVFFEARKADVADAAERNALVAVFLRHLEYFSGIVFLTTNRIHVFDNAMKSRIHFAFGLNGREVTNAINTLRKLAPFEGVPLRLEHIEAILDIRREFDLNDTDFMRMWNSPTYEDDLDQSKVMCSLGDNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWV8</accession>
    <name>A0A6A6NWV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_288244</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWV8"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="63693" checksum="0CD177BA715DF817" modified="2020-06-17" version="1">MLDPPKPGDLPHTKPCPKRLIPTIIDHNAAVYPTKVYATFARSGSVSDGVQDFTYSELANAINRVAWWLDDVLGRGPNSKTFAYIGLKDIRYSILAVASTKTDRNAFFPSPFVSTHGFDHLLKTAKCTTIVCAGPVSSYPLIEKTQAIRPDLRVIVVPPMSDWIAREPVPHYPYTKTFEEAEDDTVMIVHTSGTTGMPKVLRYTNGIMAAFDGQRYMPEDDGPMWWRLIAGKRVFCPMATLHAVGMFASLIWPVFYDTIAVMGPGDKPLTLEAVDEIHDLGIVNGGIYPPSILEEVCCSPSSLEKMKSHEFVIFTGTVASETVGKTFASFTKVFNKLGSTELGSIPTMLTPHDHWMCYKFHPYLGHHMEERKDGKYELVVRRDRSLRDFQSVFRMYPDLDEFRTKDLFVPHEEIPGLWHYQGRVDDIIIFSHAEGMDPNGLERVVSRHPLVNACLIGGNQKPAPFLLIELADPSSLATSDESARKLLDAIWPAVAEANRQCSTYVQLTRPLVAFAAPDRPFHRTLKRSVARAATLAAYADAIEALYGARAPDPLSAPSRGAANAIWSGTADHGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXJ7</accession>
    <name>A0A6A6NXJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative methyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_347222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXJ7"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="355" mass="38819" checksum="5E54106444299562" modified="2020-06-17" version="1">MLVFTWRVANMTLESLRFLRKQYFQLLPVAQLQWPDSQVLKQPHVQTWLFHNLFDSEVLNYPPPQRYQLRVLKLLVSKLEAGIEDPDEDELSDDLTCALCSLLAANLPSEVVSAQRKSYVTYSWDLTRQPEGRQEEDPGGCEFSITLLESPSLISSSGTTGLRTWEAALHLATFLATTPKGRRYVGAKRMLELGAGTGLVSVLCAKYLGTASVVATDGDAGVVEGLGTNAFVNELAGGEGPGEGQKMEANVLKWGRTLLGNAILDDEDRAPFDLVLGADVTYDTAVIPALVATLVELRHRSRPESSPLVVLLAATIRNQTTFATFERACAPLARLALYLNLLPCPFSANSAPSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY69</accession>
    <name>A0A6A6NY69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_42437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY69"/>
    <dbReference type="OrthoDB" id="21474at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="396" mass="45076" checksum="92FC5F2FA3B38088" modified="2020-06-17" version="1">MIEDHHPMPRELPTIPEEMPLEAEYRVHEAMPGDFPHETPHRYGSPFYDPQEHYAIRGFAYGADPLERSLARYGSFPNLPTAGSEDPDPAYTTPAPRRERERERERDRDPARPRERQATSGKSDKKRKRQPIEDLDLSRARAPPEERDEIMTDAPATIHSGLTGGLNRLLMRPDFPPSPDYSGGDGAEPSPMSPLKRTRHHRYRSNAGTVRSENHRDRGGERDSKPRKTSGSSSNSQHADRGDTRSQKSSRRRRSSRSEHGGETSQHHRDHHRRRRRRSGSSSPEQERRSAPRPLKAIEYRPSSASAEPSANAANQIVLHAEARAPVVNCAELFMSFVTKGPESGKGYSMNKALKRYHREMYRLNGKANPKADDEKDLWKALRLKRNDRGEIVLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYC7</accession>
    <name>A0A6A6NYC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYC7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="209" mass="22077" checksum="4332E0724396D300" modified="2020-06-17" version="1">MYLRRRGKAAGSRAAARPRSSTRCANLGTADRAAAAWLLLLVPLLLDLPGGRAPSVLLTFGRGNETRRLSLAKGRRRVRFRLPAHDDGGRGAGGPEASAARQQRKARPGPSLLGRDAGATPRQGATAARVSREAGGNARGSEGGGRPGDRGGARWERAPRPSHPCAGQSLRAKLWRLSARAVHFRASRPTSAQRSRCRPAPPPTLKTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYD8</accession>
    <name>A0A6A6NYD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">R3H-associated N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYD8"/>
    <dbReference type="OrthoDB" id="10256743at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025952">
        <property type="entry name" value="R3H-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039629">
        <property type="entry name" value="R3HDM4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32019">
        <property type="entry name" value="R3H DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32019:SF2">
        <property type="entry name" value="R3H DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13902">
        <property type="entry name" value="R3H-assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H-associated N-terminal" evidence="2">
        <location>
            <begin position="71"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="316" mass="35573" checksum="F807336F9850EF00" modified="2020-06-17" version="1">MMAIQGLSEPGAEPQLAAPSIEAWTEHTIQAVGNLTVSPQATPQRTTVSLDIPLDGHLDAPEPRPAYYRRREPSRRDSLQRRDALLRGKEGSRRRQRWENDQLLNNPHAQPPLPSDWEIRPTHPIHRVPYFLAPLWDAEFAARSAARRAKAEKAKDRSRTAVASVPKELRDKLKKAKGAKWLLRDLEEDVRGFIEGWQYGKTLAEPDGMDDTDSEDEIVFVGRDGHMSDVRLSPSPRGRVQTNMLVFDSAADDHGASFGRWLVHSIGTYYGLQTWSVTVGNPARREAYVGIGDPRSKSCRDLIESKPLPRPLWGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYJ7</accession>
    <name>A0A6A6NYJ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_345684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYJ7"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025438465" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="126"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="46286" checksum="661DEC33F8A15088" modified="2020-06-17" version="1">MKAAVSFVSLAWLSLVPTEFVLAASSPPTHSTCSPPGLRPAPGQLCSLEEGPEFAYDDSLWTHDVQCFYTTSNQESKLCLYTDANFKFGRGISIFTRPSIAANITGQYKFRHPEQLPEFLSPPAQPPYEQVELPGRGVGLFANRTIQRGEVIFVDTSVILLAREAQSSLPRSTIKKILWRALEQLPEPTQDMVFNLHRQTGGDAMADIMQTNGLGQVIGDGIRHLAIVPDAARINHDCRPNAYYRFDDKTMELSIIALRDIKSGEELTFTYIDPELPRDERRERLQKSWGFECSCSLCGASGDVVVGSDNRLELIKNTRKQMVEAASKPFELINHLEKLIDLYDQEGLHASKPRFYEIAAYTYSQLGDDKRALEHGKLAVEYWSAIAGKGSGEARRMREFVKDPKSHPSWRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ65</accession>
    <name>A0A6A6NZ65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">O-acetylhomoserine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="12">2.5.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_393031</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-acetyl-L-homoserine + hydrogen sulfide = L-homocysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:27822"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57716"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.5.1.49"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-acetyl-L-homoserine + methanethiol = L-methionine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10048"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16007"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57716"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="EC" id="2.5.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from O-acetyl-L-homoserine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.49" evidence="12"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ65"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000083">
        <property type="entry name" value="O-acetylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 13 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="458" mass="49289" checksum="24266DA8897F7A3F" modified="2020-06-17" version="1">MADLPLHFESLQLHAGHEPDNATNSRAVPIYATTSYVFNDSAHAARLFGLKEFGNIYSRIMNPTVDVFEKRLAALEGGVAAVAASSGQSAQFMAIAALAHTGDNIVSTSNLYGGTYNQLKVMFPRLGIKTKFVVGDRPEDFKAAIDDKTKAVYIESIGNPRYNVPDFEAIAEVAHKAGVPVVVDNTFGAGGYFCRPIEHGADIIVHSATKWIGGHGTTIGGIIVDSGKFDWGKNAARFPQMNDPSEGYHGLKFYDTFGPMAFAIRVRVELLRDLGASMNPFAAQQLLLGVETLSLRAERHGQNALALARWLEKNDNVSWVSYPGLESHQSHELAKKYLPRGFGGVLSFGVKGGVRAGSQVVDSFKLISNLANVGDSKTLAIHPWTTTHEQLSEQERRDSGVTEDLIRISVGTEHIDDIMADFKQAFAAASTKAGEKGSAENAQKGVVPQGEATLGGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ85</accession>
    <name>A0A6A6NZ85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_32953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ85"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="27927" checksum="4FBAD934EEB64BDE" modified="2020-06-17" version="1">MSNNANFNFPSFTWTSTSSLSSWTSTTSPSTLTASTMTSTLSASAASSTLSGTTSSACALNTIPDGTCTFLASDVGDSDISSILSRCCGSSAPVVQYLDSQDRCAYYCPAIDQPTVDLAECFLDAGLSAGCFGDDAADSDAIATAQDQASRNADCDCDADGSGSSGAAGSSTSSASNNGTASTSHVTSTLTGTGSSGTGAMGTAGTAASAGSSGVPAGAGMNSTTITSVVSPTLPPNSPTSAGGDDVDSAPASSSSGSAAAKGAVASGEFSKLGVSLVAMLFVGSAAGAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZZ1</accession>
    <name>A0A6A6NZZ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_345494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZZ1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="248" mass="24619" checksum="FFF3D3D06F6C2A5B" modified="2020-06-17" version="1">MPSRTGLEAPVNHEETWKRAVFVLEGFLGEGGADEGGVGGDAGDNGGACVGGNAAVGTVTGVFGSVTGDDFARVCDDGGLVAAASGRCGNGPREVSTVEGAGSVQPFPSLFLFSARPLVLSGTATPPAFSAAAAAAAPASCLFSPVASSRTRSGPLSRSLPPPQLSLALRAATLLPLFAASSRAALPRFLPASPATAAVVLRIDPRFDPAGPGRRSAAVRALVRVASESVSLPAVFAIASALLALAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P059</accession>
    <name>A0A6A6P059_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_24905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P059"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="193" mass="21903" checksum="DBCD8ABE6DDF3AF1" modified="2020-06-17" version="1">MRNGLARYITVRAVGYTLGGRQTSEQRAPCPHIKPRDPSRHLATHSSRIPASAYVCRRAPLQACPPHHPTNRPTARFDPARSTPHWQHTRASPLPNHILSRRRSAAPWPPSATVRAGASRPRHASNKRPHRTVSMRRSNRPPRPHRMYAFASAPVRQLNWPARSTPRSFLDNECTRYDILPPSSLSMRNSCRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P087</accession>
    <name>A0A6A6P087_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_343632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P087"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19319" checksum="34EEAE09005C4B5A" modified="2020-06-17" version="1">MTWRRATGSGHVPFEVPARILSRPPIERGSELRLFISRRFRAPFRRTSTAHHSGVNAPRWSRGSLSTPKMHLSQQHPFFGSLYLYGGVESIYLYWYRLGGSTPPDNPKSAWPCLLLASDFSSFSRPAEISPPREKSHVASPTLRLPTARCGGCRLWRCFRREPAQSGPPASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0B3</accession>
    <name>A0A6A6P0B3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_26567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0B3"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12577">
        <property type="entry name" value="RRM1_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12330">
        <property type="entry name" value="RRM2_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000466">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein HRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000025">
        <property type="entry name" value="RNA-binding protein Musashi homolog 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034156">
        <property type="entry name" value="Hrp1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48031:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48031">
        <property type="entry name" value="SRA STEM-LOOP-INTERACTING RNA-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="83"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="311"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="185"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="482" mass="51177" checksum="9F043A6DEE6DA3E7" modified="2020-06-17" version="1">MFIGGLNWETTDQSLRDYFSQFGEVTECTVMRDGPTGRSRGFGFLTFKDPRTVNIVMVKEHYLDGKIIDPKRAIPREEQERTAKIFVGGVSQECTEQEFKQFFMRFGRVIDATLMMDKDSGRPRGFGFVTFDGDGAVDETLAQPLEIHGKPIEVKRAQPRGNLRDGEDDGRKGGKFGRGGDKFGRGSGSSMGGMGGMGGGQDQSSGFGGQDNGAGQAGQGGSQGGMNGMTPAMMAQYWHRMQQYFAMMQQQMAANVAQQQQPQQAPNMNPAMMQQMMAMQAMRNNAMSPSGSPHPQSPGPAGISPAMMQQMQQMAAAQGGGSPGGPGGMQQAQQQGQQQQGARPGYTAQEQLAFEQQKYEQQQARRMQQYAQAPYGAGGPTSWDGMYDDVPQPHMPPAGPNHRGGGGGGSHHGGHGGYRGMSPNVRGGGGGGGGGRGSQPPVQPSNAPANAPTGPKNAGKPGANYRGGGRGGHRGYHPYSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0P4</accession>
    <name>A0A6A6P0P4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_421530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0P4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="20465" checksum="187719F1475D4D74" modified="2020-06-17" version="1">MALKAGAGVEVCGACRNTGSGTRSRAVTTLAPLLSPAGSPGRMLADEDQACNRTGRTLPGARSGWSAKAAPRLRTPGTGEVPLSRPRVATPPRPCPPPKPPARGRPRVGRAHASLPQIDCCKAVTDARLAKERNSISSPARLPNERTAQPAGLAGVICPRWVGEAGVAGGEEKAAFSLAGPTALLHISKAGRHGGQGSGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1I4</accession>
    <name>A0A6A6P1I4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GmrSD restriction endonucleases C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_385890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1I4"/>
    <dbReference type="OrthoDB" id="3162605at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="GmrSD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094:SF15">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="GmrSD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GmrSD restriction endonucleases C-terminal" evidence="1">
        <location>
            <begin position="78"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="20332" checksum="7E45ED26E11F2B3B" modified="2020-06-17" version="1">MPMPTPPNIPSTSAAYSQLAGLTVAAQGSGDGYDRDLFPHWISQGNSCNTREVVLERDGTNVVVGSDCYPDSGTWYSPYDGDNWSQASDVDIDHVVPLANAWRSGASSWTTSEREDFANDLDNPQLIAVTDNVNQSKGDDGPEDWKPPLTSYYCTYAKMWVKVKSVYDLTVTSAEKSALTDMLDTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Z9</accession>
    <name>A0A6A6P1Z9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peroxin/Dysferlin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_20595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Z9"/>
    <dbReference type="OrthoDB" id="5586090at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peroxin/Ferlin" evidence="6">
        <location>
            <begin position="358"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="457" mass="50623" checksum="3961FA5224FF570C" modified="2020-06-17" version="1">MAAFGKQSLPTNSNISRDFVEPAANYGMEEQPDTPWTSHMSSTERSADGGSSQFASDPNPPTYAAFSPATLGHYPTVNKQRSTILVHQKSPLLVATPPQITRALAYSHPFIHPLNKFVGLLSWTTGDPWESFLLVAAFWAVTLYGDVVVEWAGPVVAVIGLILGMYARRYSPLSSTGWTGEKGQKGHKRAVSEGSTRHHKSLDEIVDTLKLFTSRCNILLDPMLRLTDFLSTQRTATSATTRPALTTLFIRTLCVTPIWVALTLPPLQIINTKRVVLTLGTIVLSWHSRPARVSRTILWRSNTIRRICATVTGLDFGEPELPSAKKTDGPSLSARKQPKSANEIAASLAAKRRPESTGIRFTFTLYENQRRWLGIGWTASMLAYERAAWTDEHLNPAPPIDRFELPEVEGGHARWRWVEGSEWKIEGAEKSSGSNGSKNNSQENAGWIYYDNKVGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P210</accession>
    <name>A0A6A6P210_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_17549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P210"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF152">
        <property type="entry name" value="OXIDASE (CODA), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="59937" checksum="B975BEA4EC3410A1" modified="2020-06-17" version="1">MTTTALPETAVDGFDFVIVGGGTAGCVIASRLSEYLPEKKILLIEAGPSDYMDDRVLLLKDWLSLLGGELDYDYGTTEQPMGNSHIRHSRAKVLGGCSSHNTLISFRPFEYDCQVWERKGCTGWSFKTFTRVLDNLRNAIQPVHYRHRNQLCRDWVQACSSALDVPIIHDFNHEIRNKGALKTGVGFFSVAYNPDDGRRSSASVAYIHPILNGQEKRPNLTILTNAWASKVDVVGGRAKGVTLKLQNGEERSLVAKAETILCAGAVDTPRLMLLSGLGPKKQLEDLSIPVVRDIPGVGENLLDHPESIIIWELNKPVPQNQTTMDSDAGIFLRRQIPNAAGNDGEIADIMMHCYQIPFCLNTSRLGYETPIDAFCMTPNIPRPRSRGRIYLTSADPSVKPALDFRYFTDPEGYDAATIVAGLRAARKVAQQEPFRSWIKREVAPGPKLQTDEELSEYGRRVAHTVYHPAGTTKMGDVTKDPLAVVDPTLRVRDVQGLRVADAGVFPEMTSINPMLTVLGVGERAAELIAQDWGWKGLEKQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P227</accession>
    <name>A0A6A6P227_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_320555</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P227"/>
    <dbReference type="OrthoDB" id="27823at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120104">
        <property type="term" value="C:mitotic actomyosin contractile ring, proximal layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106006">
        <property type="term" value="F:cytoskeletal protein-membrane anchor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07651">
        <property type="entry name" value="F-BAR_PombeCdc15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000045">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000164">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="13"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="928"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="317"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="633"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="678"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="739"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="755"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="785"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="800"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="869"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="892"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="988" mass="107173" checksum="AD3953CBAF730C0E" modified="2020-06-17" version="1">MPGTVSETPQVPLSFANNFWGKDDAGVAPLLDRMHNAKVTCDELKSFYNARTAIEDEYSRKLLSLARKPLGSSEAGTLRMSLDVVRAEVESMGKAHQKIATQMKRDLDEPLVAHAGGMKERRKIIQGGIEKLLKTKTQQTVAVNKSRDKFEQDCLKIKGYLAQTHMVMGQEERKNKAKLEKTRIQMSTASNEYENAVKLLEETTGLWNRDWKLACDKFQDLEEERIEFMKSSLWTFANIASSVCVSDDESCERIRLSLEDLDVNKDITTFIQQQGTGQEIPDPPKFINFCRGDIDETDGEHSDDGGYSTAQFQRQMNPAMRTSSPQPSLFESHHDPDSPLAREYGHKEPPPQQPPPQNAPPNQSTNPPPAQSKGNRVEMRGGAPPMQPQQSQMENIPRIPYNEHPMDGMTQFCRFDPPSGRSSVASPNRPSSRDDSQSEYSNPTSFSSMEPPSGNQSPTKQIGGGPSMSEQQQLQKRKSGFFNSPFRRRSRHEKEQPQTGPMTAPSSRNTWGPSAASSQGGNNVGGFGGSGGRARGRNFIENGREQHTASPEPVDPRANFQLNIGNNVFDVESPDARQQPQARAAPNDELDPIAQALAELKGVTKQSSQRVSADRFHGLSTPIPPGTPSMANTPSSSLSTPLASASALQGRTPPPSYEAPVSRLGAPQPAHTARQMKKTTQMYQDKTASMFNGSGGGAGRSAGSRPPTRGSSNQSQEVVRATSPAPGRPTSPRPGLYEPQQRTLPQQQQPAPQQTFRATSPNPYASNAVGRPRAQSSSPIKPRGGDGYGSYGRAGGTASMASSPGHTAQQASRPVSPQPHFGSSAGISRGSVDMRATSPQPHFGRMDQRPGSSRGGDMALALAQSEGSVYGGSQRGRNGGNGRPMSSYYGSGNQGGADGGYQGGGQLTTRVRSKSVAEPRQFTKDGRPILHFARAMYMYQAAIPEELSFVKGDTLAILRHQDDGWWEAEVVGKRGSPGLVPSNYLQAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2C5</accession>
    <name>A0A6A6P2C5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_285287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2C5"/>
    <dbReference type="OrthoDB" id="2264294at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="644"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="715" mass="81598" checksum="3FC20861CA4E4C52" modified="2020-06-17" version="1">MSAGLPDAGLVITRPRRPCDSCRKRKSRCDMNPGDPSCVLCRFHHQECTFVEDARPRKRKSVAREEDNGPPQDEPIKRLSVLAEKERDREEGVEDGTRHGAHQSHVRDDYANLKGPSLLKRTLGLQNHRHSKFLGSTSEYEQKLLALDALKTKDEIPIGRSCLRRVNERHTFLLHPDELSRNNEDEFRDLDAIEAIVSPHGPALVRLYFRIVHPSFPILHKKVFLEKYERTHREFAPPLLAAVYILALNWWSYSSELALLTKPDVPRLEKLALKTMNDIIHRPKLSTIQAGLLLLQRQEGDSWALTTQLVGLGQDLGLHMDCSNWKIPLWERGLRKRLAWALFMQDKWAALVHGRPSHITGDDWTVKPVSETDFPEKAIDEDDEDGSTEVEKGRVLFSEMIKLTQILGDILSTFYTQRAEEEIRTNCAHGVRWLLERAKPMQIRLRDWFSQLPECLRVENVKMRKLSSTGYLHLAYFSTEITLHRCILRYLSTEQDQALILICRGAAQARLDSAMEFVKSLKPEHLQSFWYCASKYCFAVIGSFVGLLWATSSDKEDASLYKQRLEEYRWMLRLSCRSADFMERALDMLAHSTGVLVMAIPEITNSAQQPTVQVQSGSKASSGFDYVEHVEELEHGDDGRSRLSQDLSGDEPTQTSMWLDPTRSLESLQHMDPQRQMDGFGISTMGIRPGTSSFLNDGIDFVIGETGYTSDSEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2H8</accession>
    <name>A0A6A6P2H8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_284474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2H8"/>
    <dbReference type="OrthoDB" id="5420895at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611:SF2">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="16"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="257" mass="29116" checksum="69C11032E5DB6B74" modified="2020-06-17" version="1" fragment="single">MEDQDAQTREAMDYWGYMFEENKCGTKKLNQLLSGIWDHISKNIDPAEYQDVNPTQLAAFYRAVGGDYDALFVETPPTSIAFIYKSIGCLHSLQPAPDDDGYGAPQIPALKKKGYITWQTIQLLLGPEEHVPFLQNAVDKFDIIDPETNRPFPKLLPREAFPDHPDPSMIEWYEDVANKLRAEAEQQGNERRNRTNVGTTSPTAEAPNGGSAHHRRNSSEESKDGSADERTGAAEYFRNPLYRNREGRPTVVHRYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2H9</accession>
    <name>A0A6A6P2H9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mannosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_321100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2H9"/>
    <dbReference type="OrthoDB" id="497541at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF2">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE ALG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="746"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="770"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1149" mass="129818" checksum="0A07BBE8966E77C6" modified="2020-06-17" version="1">MFFLIVPICCDKSTMARKPKKSPPPQASQQPGVPIKNLPDKPPASQSSPTLEPIVAFYIFLAARTVSAFYAPIQDCDEVYNYWEPTHYLNHGYGKQTWEYSPQYAIRSWVYSGLHAAIVALSRPLPVVTTKTCQFYFLRLILGTACAACETRLFAALSRAVNPRVGLFFMLAMLSSAGMFHASTAYLPSSFAMYAGMLGTAAFMDWKGGIKTAQGIMWFGIGASIGWPFAGALALPWLAEELVLAAITGQVVDMATRVLDGTVRSMIVLAVQSAIDTFFYKKLVCVPLNIVLYNVLSSSSSRGPDIYGVEPWHFYLRNLALNFNAWFLLALLSFPLLVLHHLFRERARRGGSAGAQTFLRTLVFITPFYVWLAIFTLQPHKEERFMYPAYPMLALNAAMTLHVVLGYVGSTDPRDLSSHVPPALKFAAVMAFVLGSVDLGLLRSAGIVTAYGAPLEVYGPLMENGVGGEGAAGNVCLGKEWYRFPSSYFLPDGMHARYVRSAFRGLLPGDFSEAKTGFGVFPGTWLEPAGMNDRNEEDLGKYVDISECQYLVDSRFAGRSDDGEEKVEEVGVHPDEPDYVRDEETWERVACAPFLDAERTGTLGRLVWVPDWGIIPARFRRRWGEYCLLRRRSLAPSVDPQLQAADRAGRRSAFVIMLVHMDGAVFLPMMPNSIKKPDRALDLSKAARTPLLEASFSASFFAPVVFRSLEMEEFKLWARKNCNPERVKEISQQVEQRFRDQPKHTAYGALLAIATAWLLIATARHFLARKQSSRPGSPDPEKKPAYNRSAGSKGPDRPPGVWPPSDFKRPTASPYPDWSLEHTKPLPYRPFRYGPQYKVTMGLRNMDWDDWIEIDNHYPRFHADKARRIEDRGSRCCRTAPEAFDAACELVEELVDYLPQRYPSLFRRTGEGKMENLYSGERFDVTERPLKEDPMQMAARMVQDDLAIMLEKPDGQYYLLAGAILLAGFWRLEDKFGMVLSEIHTSGEVPQFKEKLEKGMMNFFRRVKPENPVLRNNYFIQVDDQLPWSTSIGDEDSEGIGWYTAEKNKAIEHHYFRSERQSLRRLPRSGGVVFTIHTYFHPITEICAEPYVPGRLASAVRSWGDDVSKYKGKERYQDVLLEYLDRKHEEQVADGLDLSKEEEVRAYPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Q3</accession>
    <name>A0A6A6P2Q3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Permease for cytosine/purines, uracil, thiamine, allantoin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_284393</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Q3"/>
    <dbReference type="OrthoDB" id="5428495at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G03000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="478" mass="52878" checksum="97C64E68D79CA06F" modified="2020-06-17" version="1">MFHAFERQLVKYNLEARGIQRVEPDERHDLQQLGYTQVGMFWFSVNLAANNITLGMLGPAVFYLSFLDSSMCAVFGMLVGCVPVAYFATFGPRSGNRTMIVARYCMGWYPVKLVVILNIIVLLGYAMIDCVVAGQILSAVSVDGSLSVVVGIIITAVIAWVVTTFGYQMFHYYEKYAWLPQLVAVSILAGVAGPMFDLDTPSDGEGDMRTIIGNRISFFSLCLAAAVTYSGGAADYFVYYPERTPGWKLFLITMSGLSLSFTFAFIVGIGLASGINSNPVWGDAYSVSQGALIVEGLRPLGTFGDFLGVVIALGLIANLVVPTYSGGVDFQTLGRYPYRVPRIIWNTIGVIIYTVCALAGREHLAEIFTNFLALMGYWVCIWVAIFLEEHLFFRRNKIGWNWTIWDQRDKLPIGIAALIAFLVGWAGAILCMAQVWYIGPIAALVGHYGADMGNYIGFAWAALVFPPLRWWELKKYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P311</accession>
    <name>A0A6A6P311_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P311"/>
    <dbReference type="OrthoDB" id="5353310at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="119" mass="13035" checksum="0D5BB4C495DC1BF0" modified="2020-06-17" version="1">MAGIRDPAFWRRFSMAVHLDDEEKQQQQSATRPSLKHSDSWLARQQAKRSRRTCICWIFWLSFFAVVAGIVVVVLWLKAEGLLDDIRIGGGDDADDAASSGSPTASPTASPTASPTSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P357</accession>
    <name>A0A6A6P357_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P357"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="62" mass="7161" checksum="089C88124EFEEE8A" modified="2020-06-17" version="1">MVVICVLGKLDEPLEDNHTLVERRLRRRAPMNSDSSSLCTRFKQQRLCRSTGKLRMRAAVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3A6</accession>
    <name>A0A6A6P3A6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibroin-3 related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_420886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3A6"/>
    <dbReference type="OrthoDB" id="5401332at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037504">
        <property type="entry name" value="PSI_induc_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40018">
        <property type="entry name" value="[PSI+] INDUCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40018:SF1">
        <property type="entry name" value="[PSI+] INDUCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="53371" checksum="13ED4908862A5F69" modified="2020-06-17" version="1">MPILYHRQDIIDDLNGAKDTFSSWDKCMAESYCKYPVIVAIVVGSLIAISVLICCMRCLCFGKECCCGCLSCCNACCPSPRRRGHKELSNSAPPPMPYGGNQPAYGGAGPTAQQYRAPLQPSYAQPQPDRPQFATFDVSSGKGGNYNEDALPAMPTWEQAKSTKVEETVAPQQTEEVELNKLDKDGREVGAEGVGAAIALPNSGDEASIRPGALPRTNTGFQSLDRTNSPYRGSPTPGVQRTNTGYASIGRSNSPYNGSQASQQGRPGMQRSNTGYSSAYGSTYSAGEQAPFIGGAMGRPDRYPPNNGVAPYHDQHQYGQDGGQYPQDNPAYGQDDNRYGQGNTQYGRADPQYGHDDPYRQDNAQFRQDSYGQAPYGQAHAQAPYGQASYGQTTGQAFGQPRYARDNMSPMHSPPPAVTPLPQLSSPPPALQAGYSAYRPAEQPVYAPRSYTPANEQPAAVFEAPGDNTFVPQQQQGAGYSSAPSGRKPVPGSQPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3S4</accession>
    <name>A0A6A6P3S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_362895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3S4"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000006">
        <property type="entry name" value="Gamma-glutamyl phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="6"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="480" mass="50755" checksum="EFC9D1A8DEC5D914" modified="2020-06-17" version="1">MSLTNATPQEAARAARKSSRALAVLPAADRDRALTAVHRALADARDDILRANLRDLEAAMRAAEAGTLSQSLLKRLDLGREGKYEDMLQGVLDVRDLPDPIGVIGARTLLDDDLVLERKSCPIGVLLVIFEARPEVIANISALAIKSGNAAILKGGKESTESFKAIAAAVSRALAATAVPSDCLQLVTTRDAVGPLLELDRDIDLVIPRGGNELVRKVKASTQIPVLGHADGLCSVYLKADCDPAAAARLVVDAKLSYPAACNAAETLLVDEDALGTVLPPIAAVLLERGVSLRCDEAAKATLGATLDAHRAAILQDADEADFRTEFLGPTLAVKTVPRAATPEAATDTAVAHINEHGSHHTDAIVTASRACAERFLAGVDSASVFWNASTRIADGQRYGLGAEVGISTNKIHARGPVGLEGLTIYKWLLRGAGHVSADYGAGGKKWKHRRLPVGDDERYARTDEELDVLRAFRARANGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3W3</accession>
    <name>A0A6A6P3W3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_204706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3W3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="455" mass="50029" checksum="9CAFE24659843BED" modified="2020-06-17" version="1">MRDAATQTPLGWAMAETGFQFANAASQAIENPRVAQAAHPAQPRPATASDAGPSGLSPRLESLRGNPFRANSTSTKRGRGSSSKKRLAGDILGHMVQVLDANAMCETQVKRRRMTTAADRELYTLNRRRGVCSTCKHRKQKCMHNLPQPEMHERSRSRTKALDDSEPGELPNQATVPSGSTPPMSSQILKPAVEDLSVTLNQLFEPYTSLIPAWVSQSALTSLGSDNATSCMGDQLARVASPEFDNLEDISWGYERVLLYGPALGYGQPMGGERWAQPSDSWLSRVGYGGRMVPVCPEILASCPHTPKERVNDHTFQRSLSEFSGWATPYPQMSLVHNVDSVHLANLDLDLSFPTYVGWAFNASQTDHSRNKHFSGFGRDAHLVESAQRVQLADSVMNVRRHPTKPTGMHRVMQPSRAVLGPRLESQHAPSQADEGLDGDASSDFRIDLEFAWSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3X5</accession>
    <name>A0A6A6P3X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cryptic loci regulator 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_214352</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3X5"/>
    <dbReference type="OrthoDB" id="438224at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070824">
        <property type="term" value="C:SHREC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038986">
        <property type="entry name" value="Clr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031915">
        <property type="entry name" value="Clr2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018839">
        <property type="entry name" value="Tscrpt-silencing_Clr2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046:SF1">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10383">
        <property type="entry name" value="Clr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16761">
        <property type="entry name" value="Clr2_transil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cryptic loci regulator 2 N-terminal" evidence="3">
        <location>
            <begin position="57"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Cryptic loci regulator 2 C-terminal" evidence="2">
        <location>
            <begin position="347"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="77868" checksum="D01A5B445BFF8585" modified="2020-06-17" version="1">MAQPVIIPLPSSFSDGDPNHQPGKHGTYLVDPPTIYLEKLADWWMRHRGQKAENVRYRFDRLPSGYRCFGKARLQNPKLSDKWLYGHPKHSTYDSPLKFWPHFRALMENGGNPTGCDCVVCGGRKDTNKSSGKLGRPKLADSVRTDEEGTPDVYRELIDGLRKDGSLDIEIREPMSMDWRATREGTEAMIAKAMTQPNWIPRIGEIVLFVRTIEDWQEISMDHETGEYKIFDKTTNASGRFPSWEAGYVSELAEEDVSLNDLVMETKKSMGRNYSGFRIEAFAAGPQHKYVPLHQIRPFFLWERLLKGLDIRLYHASIIIAMKYMSSVSLLEKFHFRGTWPKGTILCKGVYLGAELLLVGDTIRLFPGPEPGHDPAKVTDVIQLTSIRLELSDLDKASANDYDDGRPYNLAIRLGGRRYTLDPDKATGYAPLSPHQCPEVLHQYDDWYYTHDPSKFVDVPFNRVLGRCYDGEAMLLWCADANSSESTPDISTGVAAVRYGRHHSTKRDPRIPDGKRWYWADCRAQQLELDTFNGHYTADRDPERDPKVLKKHCKVMMGVAQEEDRQELKQPNMEQRHLHGYAASSSMVRSALHDDNVPTTGGESESDVAIAAAMMAEAHDEEMPSDSQPFGRKRSRSVASRGSKTVVPTINVEDSEIESDDQLAADMAGQEFGIGSSRGMGSMPKKHKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P443</accession>
    <name>A0A6A6P443_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_340646</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6123at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142:SF1">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner centromere protein ARK-binding" evidence="9">
        <location>
            <begin position="1175"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="337"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="624"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1175"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1233"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="692"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="786"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="812"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="846"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="877"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="944"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1013"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1068"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1154"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1252"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1281" mass="139760" checksum="38554EF38B5C844D" modified="2020-06-17" version="1">MAPARSQQTPVGSAQWLLAERRHVNQLVVEGCEEFAFSANEQMEWLNEHMHDVFNRHQVNVADVFKTPGKLRGKTPRTARKRPLENRAPLTDIFAPNTQAGSNSPHKTLNSGQKSTLFQNLNKIQIAADTDFQETQQSPSATQNKAHGGAGKENIDSGYYGTTQEEMDVDAAPLAKVHTSKDLTQQKHARHVRVKSLGNGDIMPSGDEGRVTTDESFVSANEEVLGSKAASKGYLPEDHQQRPTQDDKDVAMVDAPDAEPDDQQTRVISNQYSMSAETASAMNSMMEADGAQTQDDIDEDVAGSRSTSEGSSPVKPLVRKSSLTFAALPAREPLATKKSVGARVSRTSNTEYSKSFGGSQYGRATGGKSIGGSHNVDFDDPMDVDQENRPPVSREDSETTKLHNKTSTQRLHERINMLGQSKETGSSRSLHAAIPNQQPSYPQLPAQSFDSDKNKADVPATMPPRKGSPTVQAVNSSDDEEDWIAPVSSAPARPQLEKSNSADVMEQINNKTTIGAFEIPDDMDCGSPAVANPSPAVIPSRPGLGHHKSASASALSSPAKSTVQSESTHHKAISVSNPEMPIVEESTTPAGSPNVRRHMDGPLSASKAKLFSVLKSAKGIFASSAGVSAQAKMEALSPVPTRPRNPAQAPGFGQVLSPKRDARAFAQPDDNIGRETDVRVPSNLGSPTNPAEGRRTRSSTEREQKQREKEAKEQQRIADDLERAREKERQKAAAAQKQEKAKEVAQSGKKVQPKAGPQAKHDEAAREDMPPPPPPKSVQSAGTGQKLREPRRLAKPSKETLPRAKPAPVSIRTASQRINQQQPAANSLSQPVQDAHPPAPPPKQQNVTTKASNTSLQSSNSATSYKVGASAHGRPRALIEAEKKKQQEERAAQRKAEQKREAEQRRKQEEERREQQRKAEQLRVQEARKTAQKRADDVKRQQEQQRAQAAQASQNRPQSRHANEFANMLNQEKVPAHPRSDLGNARPLNRMHTVQDATRQYPPVNQAKPAKRPHPEQEYGQDNKRRKTIEEDEPKEEASRRSVMAPPTRPSNIRKEPNKFQHGYIPAPSNTQHAASLFKSTVTGQHHLAQGKSTIAPVSGNSGTSGHPNDMVKYSNAKIPFAEAPNPPPGAPGHSNIHSYPHKTPVRAAPGVSGASTAPKSSPNFPAAESVQLPDINTDSEDSDSSPSSFKQPSWVASPALNEILAQQQLVDPETIFGPIAPLQMEEIFKNKDRQKRFRDRTSSANWSGSDRLTEEERKKDREGRAKLVRDGGWTYAHGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4X3</accession>
    <name>A0A6A6P4X3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_195656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4X3"/>
    <dbReference type="OrthoDB" id="5395727at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="115" mass="12554" checksum="1CEF34FB4619D9DD" modified="2020-06-17" version="1">MAATESATNPIDSTPTGNPSAGDPFAKQRTGDNDPFAGDKLENIAGNDNMRMGSQSPPSDRRMSREWDAAKVPPSQFQKRKGSIYSTPSSRDGHVKGSTRDKAYHDKLKEKGWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5R5</accession>
    <name>A0A6A6P5R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ferric reductase NAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_384594</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5R5"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000103">
        <property type="entry name" value="NADPH oxidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000004">
        <property type="entry name" value="NADPH oxidase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="270"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="65054" checksum="6764A8DADA739020" modified="2020-06-17" version="1">MSVVNSLTGKERSRWPPLTRMLMAGEMSGEPPRALTWREKVDRWMVNEGYRRVFVGVFMLLHAMVFAFGFMNYQVKDNLNGARDTFGLTYPIARSAALVLHVDVALVLFPVCRTLISLARQTPLNGVIQFDKNITFHKLTAWSIVFFSWVHTVAHWNNLAQFSAKNGLGFMGFILGNLSTGPGWTGYVMLIALMAMVFTSIEKPRRANYERFWYTHHFFIVFFIFWSFHGAFCMIKTDFAPFCAGIGVFWQYWMWGGFIYLAERVAREWRGRHKTFVSKVIQHPSNVCEIQIKKENTKTRAGQYIFLCCPEVSVWQYHPFTLTSAPEEDYISVHVRCVGNFTKALAKSLGCEFEKRGSGAKGAGGAAPGVPQVKGVAEDAAGADPALRRVLPRVYIDGPFGSASEDVFKFEIAVLVGAGIGVTPFASILKSIWYRINYPQGKTRLRKVYFFWICRDFGSFEWFRSLLLAIEAQDLDDRIEIHTYLTAKIKADDATNIMINDANAEQDAITGLRAPTNFGRPNWDMIFKSIRKIHAPAEAGVFFCGPKVLGSVLHVKCNMYSQPGFNFVWGKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5W9</accession>
    <name>A0A6A6P5W9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_384622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5W9"/>
    <dbReference type="OrthoDB" id="5210591at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF59">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="98"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="422" mass="45724" checksum="B5461FE9726D8FD5" modified="2020-06-17" version="1">MHLPPLDVAVFPIVTMSYGYNGNYNNNNGSSLPPISSISTAPSYYAVSSPSQLQYHNQISTPTPIYPPDAPEFSSVQELARRTLRDRRAALHQVERLSGQFHRLYLLNLHDGRRMVLKCLPASTIRLMRHEQHSLETESTVLEFITRNTGVPVPAPLIYDGSNHPGSSSSSRQHQRGESTSSPSALTRASGSSSTNPLNAPFLLRSFLPGTPLSSCAARLLPATRAHIDRTIGLHLSALSNLRARGFGPARRVFAGRGAATWREAFLSLLEAALRDAEDLLVSLPYGSVREWAQVAARAGVLDGVREACFVGLDFGCEPNVLVDEASGAVVGMLGAGNAVFGDPLMAAVWEGAPVDVWRGFGRQEAPVEGGVESVRMYSMYRAVVSVVAHYYRPRAEQAELEARRALTGALNQLASLQHIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6E3</accession>
    <name>A0A6A6P6E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_317389</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6E3"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000095">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF365">
        <property type="entry name" value="ENDOCHITINASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="7"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2459414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="395" mass="43238" checksum="FAD2C78780007A8A" modified="2020-06-17" version="1">MGGGEGYKSVVYFVNWAIYGRNHNPQDLPADKLTHVLYAFANVRPDSGEVYLTDSWSDVEKHYPGDSWNDTGTNVYGCMKQLYLLKQKHRHLKVLLSIGGWTYSANFAAPAATEAGRRRFAQSAVQLLKDLALDGLDVDWEYPQDAAQARDLVLLLRETRRALDAYADEPHFLLTIAAPCGPQNYSKLRLAETAAELDFINLMAYDYAGSWDGRAGHQANLFPCGSDPGRTPFSTAAAVDAYVAAGVPRHKLVLGMPLYGRAFCGTSGPGHHYHAGVGEGSWEHGVWDYKALPRPGAHVHFDRELGASYSFDSSCGTMVSFDSLEAAELKAGWVAEKGLGGAMWWESSGDKCGEESLIRRVVGKWGGLEGGRMDESPNVLVAPGSKWDNIRNGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6M1</accession>
    <name>A0A6A6P6M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein suaprga1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6M1"/>
    <dbReference type="OrthoDB" id="278212at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.280.10">
        <property type="entry name" value="Mitochondrial glycoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003428">
        <property type="entry name" value="MAM33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036561">
        <property type="entry name" value="MAM33_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10826">
        <property type="entry name" value="COMPLEMENT COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10826:SF1">
        <property type="entry name" value="COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02330">
        <property type="entry name" value="MAM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54529">
        <property type="entry name" value="Mitochondrial glycoprotein MAM33-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="36090" checksum="B40EBAD80A1D475D" modified="2020-06-17" version="1">MMSLRSFARAVPRTVSRATLQPARSQLPVRPLAVPKMWKPTRPSAFISAFHTIPSRRAPQEGDNVTQELHAKLCSELELEAQMPETDKYPEGVQDYLDQSEYTLQDLPGKEEIVLTRQYGDETIKITFSIASLQDMPEEPEDPAYDDEEMDETMKDAQAPPGQKRPVNARGGKENPDVAPEDKVSPADQEDMNEEYGDEFDQGQSFPIGLTINITRPNKGAISVAASTSNGALTVDNVFFYPDANMAEPKDAETVFSRQGIYAGPPFGTLDEDLQSLIEQYLEERGIDAHMMLFVPEYIDYKENREYLQWLENMKNFVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P704</accession>
    <name>A0A6A6P704_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P704"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="513"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="730" mass="82259" checksum="69CD6D56A0457C55" modified="2020-06-17" version="1">MKFIQGGPGRFQISSEGNSAKIGLRLRISEGFKHWYYGNHNPTRNLDQVFPGYVDGDNKPEQNRRDDDSADSICNLKEAGTLPPGMKAPDAPSKSTNNNVATSNNKGGLARGTRNECKTLDARYDKRGDLTVSESSKPFDLISNMDNKPTTLFDEYCMVVTRKYSQDNKLESTTLKIQSPFIVTALRNIIKYSPDVPLDVSDVIDIGDPPAIIYHYRHELATYACQIAGADENSLQTKLHINYLLAYLRVCMGDDMDQCEAHLAKGLIKYDWLWMLYRPGTLVYSSGADQLYFFERSEYVECGGGHAFIVHCHVINYDGVSVGKEVRKVIFAQFSGPRELSWLDLLPLEYCDDVDGLKRRLTERGRVFLSLRGVHQRAHPEHGRVIVDCKTYQQRVFPKEMYKKRMKIESKSSCVCRVCSKKVAQTKDDYDHELRELSEEEMMLCSATVYGFTLKHHKWKEFRVNDLAEIDWKTDAIRGLVMDDAQKKVILSLVTSRLFVEGKETGVVEGKGKGLVVLLHGTPGTGKTLTAECVCEHLRRPLYIVGGGELGIKPADLERNLKDILALSARWNAITLIDEADIFLEQRSATDLARNSLVSVFLRELEYFTGILFLTTNRVERFDDAFTSRIHLALQYPDLSRAMRRDVWAYSLARFPAADVLVDVGPDSKDLDVLAREDLNGRVISYAVRTAKALADAEGEPLGVAHLKDVLGVYQKFNRRMLDGKSAVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7E2</accession>
    <name>A0A6A6P7E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_281033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7E2"/>
    <dbReference type="OrthoDB" id="3438962at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="17963" checksum="7DABD598A5FF794A" modified="2020-06-17" version="1">MSGLNPTGPSQPTKDQAYTTAGNPASINPSESATARTQPHGKPFVDHRDPPAGQSAANGWTPQEPSLAQGVHGAPAGEEKAGLTAESLDRLHEFDGDEKMATAAEGKVASAVGKVDGFEKGTGSSGGQIDLASDLDRKKAEQQPYREAKHSQREKNVDVGGILGQRGGPANPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U9</accession>
    <name>A0A6A6P7U9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_281243</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 15">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 15">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7U9"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000006">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000011">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="50"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="17">
        <location>
            <begin position="249"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2460015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="450" mass="50282" checksum="EE1056EE0FAB9279" modified="2020-06-17" version="1">MRGEICHIHIGQAGTQLGNSAWELYLLEHGLKADGRPDPDNHETIEGASFETFFTETGSGKYVPRSIFVDLDPSPIDEIRTGDYRQLFHPELLISGKEDAANNYARGHYTIGKELVDNVIDRIRRVADNCSSLQGFLIFHSFGGGTGSGFGALLLERLSTDYGKKSKLEFSVYPAPRMSTSVVEPYNAVLSTHSTIENSDCTFLVDNEAVYDICRRNLDIPRPNYEHLNRLIAQVVSSITSSLRFDGALNVDLNEFQTNLVPYPRIHYPLISYAPVISSHKSSHESFKVHDLTFQCFEPNNQMVVCDPRNGKYMAVALLYRGDVVPRDCNAAIAALKAKASFNLVEWCPTGFKLGINYQKPMCVPGGELAPVDRSVSMLSNTTAIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVASDSLEEGVEEGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7X9</accession>
    <name>A0A6A6P7X9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_370007</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901992">
        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05611">
        <property type="entry name" value="STKc_Rim15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000340">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000664">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000139">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001008">
        <property type="entry name" value="Serine/threonine-protein kinase cek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="59"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="771"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="16">
        <location>
            <begin position="1205"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1578"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="313"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="499"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="723"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="927"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1034"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1247"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1341"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1718"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2049"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="570"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="612"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="724"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="948"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="987"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1000"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1038"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1060"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1261"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1272"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1293"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1341"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1373"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1386"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1425"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1488"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1503"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1783"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1801"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1854"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1917"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1939"/>
            <end position="1956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1960"/>
            <end position="1970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="2049"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="2065"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="2085"/>
            <end position="2096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2460126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2166" mass="233186" checksum="953AAC1945286F20" modified="2020-06-17" version="1">MPPPAAPITMAPPPAVTALKQEAAAAVGNLSGGGGGDGSGGGRPITQMERSISMDIREEKEELKEAAEQSRNVVMDLALDGRVRWVSASWERVVGTKPEEVQGKPVADVLVDDKNVFAEAIESMGRDDSRSRLVRFRVPMGPSSAIRRKRESRANSRQEGARGEEGESTEQVLEEDEEDILDLEAQGMMVYDPASGGESHTMWMVRPQVIREVTIDLPEILVESLGVGAEMLANYLTALAEVGANDPGNHPPPLPVLCRICERQITPWWFEKHTELCLQEHHAEMDVQMAQEALTEHRNTIVKILDALEAQRQPRPTSGEVIASARPVPEYKGFPIGPPSTPSSGPSSGRASPASPPSRSRERPVGLGHARAKSFGIRRPAYRIVELVLDLCDTALEINMPSIKDTRTQLSTDIRTISPQSENRISQVVNWETGPSSSQDQGLAALSDDTSRLSKQKVDAVNRYRRILEYSERIRVEFDIRVQECIDAAMRKAAKIAAGELTDSSEDTTSQSGAEAEAEGEAEDDTEAEAPLDTPAEEAMFPASFDGPSAMATALGNASDSSLTARLERSTSSAAGSATRSSSPGGTQTPRSHPGAMSFVSQSKRASMQFESDAGGDSDSSVRSSVLSAGRRAESPGSEYNLSRVASSRERKRRSLILPSMMGNSRQQSPARGMVPPSSPLRMSKPRIPSGSEGVQSPPVTSPVLSTTEFSSPAIPAMAGQPHALHHHHHHHHRRQSSAAVSEHSRPPLSPRLIAVSNPQPRAQPPSIKDFEIIKPISKGAFGSVYLSKKKSTGEYFAIKVLKKADMVAKNQVTNVKSERAIMIRQGESDFVAKLYWTFSSKDYLYLVMEYLNGGDCASLVKVLGGLSEDWAKKYLAEVVLGVENLHSQGIVHRDLKPDNLLIDQKGHLKLTDFGLSRMGLIGRQKRALARKPEDTVPDLLKQGPFQRAVSSTSSRSASFDFQEHSPGQTPNLAPATGGDIGMPSYFNLSRESSVTQAKETSRRTSRNRSDSGDSEALQAAFRRLSIADESAIAKRRTPIEEEKGFPDEGSPDAYALRPSLSQASIPPNSSTPPQGSIMPPPDMTLFDPEDSNRKFVGTPDYLAPETINGVGQDEVSDWWSLGCILFECLYGYPPFHADTPEKVFENILDRKIDWPDEDAYDVSDEAKDLMNKLMCTDPTQRLGANKDDKYASGGDEVRHHPWFADINWETLREDEASFVPAPENPEDTEYFDARGADMANFDSEFEDQGATSTGTPGADYTDRPHDALSRVRSQVNSSSMKRGLIPLHIPPHVRDGRNRRLSEPVPVDDFGSFTFKNLPVLEKANKDVIQKLRAEAMQAQSKAASSLNSPGGTSPAPSLESSPVIPGPLKRTLSTNKGGSNVNRPASPSLLSQPNSSPNRQSQPSSPLLVSFTTGQNHERRKTSSGSSSLSAQNSSLHPGGFFDVPRLPNNMKPPSSTASSPIKVVKTPGAPPSLPQEKTYPGQRQTSGASTSGGSAVASPRTRSQTLGSQEGETLHRDSLSSHYKRRSQVMDISPSSSDNEDGRAKAVMKYQRRRHSSRRHSQFNLADGPVFRPLDVLVCEDHPVSRIVMEKLLEKLRCRCIVVSNGHDAMRYGMGEVKFDIIMMEFNLPQMNGADVARMIREIQNTNKNTPIVAVTGYLKDLQAPHHFDALIEKPPTVESLTEVLGRLCQWKPPPPGWTGAVQHPVPHHLAAAGGSFKSAMHPGGGRYEDSPTSNSSGFAGTIPSSSYRGSSREDSVSSSFFGDTDSRSDDVSAGLSRQTTDDWRERERDRDLARVFGGLGISGTGGGGGGVHGHQQQQPEPTQPIAVQPRSSTHGSMDSGKVLLPPLSGAISSNSDHVVHQSSAPAALEHPSMPGRKARSNAAVMAPPSDRTPPKRRPGDGTRKPPRLQESAESGDDEDEELGDKHVRAKSPKGGARGVGSGVGAGAAGAGAPGFTQLTTSTSNAGSGKRSSKLSTEMMRTNSHGSVVSVEDMAAATEALASSPPPCIDEDVVEEAKGSLARRDVEGADAALARLEGAAQTAAVVKEEAEPSKTPELRQPWVSTSVENTSVADFARKFEGEGEGEGEDEDEDKTVKRSSGAMTPPEIFPKRPGGEVVTVEAPDTTPTAGERDKGLLVGEGSESPDPDPTPKAGASPMSGGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P872</accession>
    <name>A0A6A6P872_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_281560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P872"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47930:SF2">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G04250)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47930">
        <property type="entry name" value="YALI0C12947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="688" mass="78703" checksum="F8A375DECB320F6C" modified="2020-06-17" version="1">MPASGPQKVLLKRFNVATQNATHKPEEDGSRKELWKAYLRAKESIPGFLTAIPDQTWDLLWKGESEEGISNPNSMAHLKTLVEDMDSIGKESTLEQRLAHLEAIFVEGNRQDALKEWEDSHDISGGRSVDGHKPEFLSLGIRMYAHDGNLDRAVVILQELLETYPLADPRAIISMVKALIRRGTSKDLQQAWALYQLLRQLLGTSMTMEDYDIVSLSFMESGNKDLALGVFRDMMLVGDRKDGPERDASVVQHQAMRHIQEMRSIDASKESVDSTFLAALAMLPRRFHNKWFYASWMKKLIGMGRPDAAAQVLELMFERGCRADAIHVNGIIGAWLRTGDTKDKEKAELMAWAMIQARLEFVSRRRADQLGRSAETTVSIPNKSPNDKIRVPRFLRRNVPQATIETFSVMLLHYVNRLNGDRIKQITDALHQAEIKMNSYFMNHVLVAEMRSRSYSNLWARYLRLSKTVRADVHTFTLLWDAMIKQIEQARAGRLRGYPTPRLLMRHMMTWLDELDSDWRTQMIARFTAQLYDRIIECFDKANDLPGSLVVMHAMHSRFGVGPQKRTSDSLVQEIARISFRADGKTPRMRREVQRSAAFKGNVQKVRAVLEMLRSRRLRDLEDEGVSLEDLGADELNQFNLNLFSELIRVVSIRSDTPDRVEAAIRQAKTEMNGEDLETGDRDSFQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8B2</accession>
    <name>A0A6A6P8B2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_337744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8B2"/>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="121"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="29286" checksum="55AB5149417F07EA" modified="2020-06-17" version="1">MPPKSSKKAAPAPFAAKGSSKKQAKNPLIEKRPRNYGIGQDIQPQRNLSRMVKWPEYVRLQRQRKILNMRLKVPPSLAQFSHTLDRNTATQVFKLLNKYRPETKAEKKERLHKEATAVAEGKKKEDVSKKPYTVKYGLNHVVGLIENKKASLVLIPNDVDPIELVVFLPALCRKMGVPYAIVKGKARLGTVVHKKTAAVLAVTEVRSEDKSEFSKVASAVKDGYMAKTEEHRRHWGGGLVGAKAQAKRDKKRKALEQAIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8H3</accession>
    <name>A0A6A6P8H3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_280790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8H3"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="16"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="34349" checksum="03B45FF53A362FAB" modified="2020-06-17" version="1">MDTRFTLNNGTTIPALGLGTWQSSPGEVKNAVAHALKVGYKHIDCAFCYQNEDEVGEGLKEAFAAGVKREDIFITTKLWCTFHSRVEENLNMSLKSLGLDYVDLYLMHWPVPMNPHGNHPLFPKLPDGSRDLVKDWNYVDTYKQMEKLLSTGKVKAIGVANHSRPYLENLVSKVDVVPAVNQIENHPYLPQEEVVDFCHSKGIHVTAYSPFGSTGGPLMQEEGVQNIAQKHAVSAGTVLLSYNVARGNSVLPKSVTPSRIEENKNIIKLDQSEVDELNEIHKKKGITRYVYPPFGVSPNTFAFLEPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Y0</accession>
    <name>A0A6A6P8Y0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosome recycling factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_369428</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Y0"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="5">
        <location>
            <begin position="113"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="30806" checksum="54E138941395E01C" modified="2020-06-17" version="1">MPRPAFSLPAHLARQPLQRAIGRPHQYRRPAIRARASSAGSTAVGISIASLCLLRAFATTPALGKKAGKSNKAFARSDASPPVADAGRMTPTDEIYDLSNMESGILHALERLTHNLAQLRSGGRFNPEHIENMKVALTKGAKERIKIKELAQVVPKGRTVLVVVGEQAHVKPIMATIGASEYSLVPQPPSPHNPTTITVNVPPPTGEAREKALRQAHDFGEKALFAIREARGKHHKKIRAAEVAREVRPDDAKRATKEMDDLVKRQNAEVKRIVDSAKKVIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P975</accession>
    <name>A0A6A6P975_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbonic anhydrase</fullName>
            <ecNumber evidence="5">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_280631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P975"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03379">
        <property type="entry name" value="beta_CA_cladeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175:SF3">
        <property type="entry name" value="CARBON DISULFIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="18970" checksum="51993B4C9137EBD2" modified="2020-06-17" version="1">MASSKTPVQQAVEASNEKYAASFHQGHLALPPAKKYLVVTCMDARIDPAAAFGIALGDAHVIRNAGGNARDALRSIVISEQLLGTNEILIIKHTGCGMITFRNQDALKVVQQNLGSLAKQEAEILFNADFQAFPDIENGVKDDVTFLRDSKLIPQSVTISGWIYDVHAGRVRKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P991</accession>
    <name>A0A6A6P991_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biogenesis of lysosome-related organelles complex 1 subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_384098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P991"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009395">
        <property type="entry name" value="BLOC1S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073:SF0">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13073">
        <property type="entry name" value="BLOC-1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06320">
        <property type="entry name" value="GCN5L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="123" mass="13392" checksum="1389CD639168997B" modified="2020-06-17" version="1">MPQPDDSDRRVAEARAAVTASLASVGSSLDAELRNRAQDLHSNSVAIEKQEKELAKQTAALAKESARWQKMADTSTKKLKEMGDTQNWAEMMERDLLVLEETMRLVEGKPEIESASGTGGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9A3</accession>
    <name>A0A6A6P9A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_298588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9A3"/>
    <dbReference type="OrthoDB" id="4835445at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF11">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="689" mass="77466" checksum="8698ABC6ABA85107" modified="2020-06-17" version="1">MSQNSKAGGFGQQGSRKSRNGCHRCKLKRLKCDEKKPKCNNCESRGVECPGYSKLFKWSTKYETFQPAQLEVRTKAPLPQDNIDGLLQQASKAIKDDEGVKDTKDAGTPLILKENDASKEPDSSTKEASKSTSPPSPMENQSKDQPMHEKDHEEEQIENPDDEAMEDEEEEVLPRSQSSDLIEARPEPRRQSNALAEISRQQADEMRASRSLLRRFYRMHNLSSSFNLTDFSSVLVEHYFKYVASLYSSFDSSLNPFRATVGRLWDSSSSIYFAIQSMAAAHLANSNPDMKVVGLEMQRKSYRSLQNELQLVNTGRISSDRILLTILLLGLSTCWHDSGDLGLSHLAAARSLMYPRLVQAGPPQDRRSERQEQFFEESMIYWEMLIGFVSQDSRVQAHSMWESALARRASLSPERDTSPQHTSGSERKFLPHPWTGVAPRIQMLFAEVGRLIQRYRASGLQDDIEALELARFLEEELLDASLPPVDALVDPGDLNTSPAHFLAVAEGYRCSGLLELYRVFPHLLRQRLGTSSASSDPHAEDLGLHDFPSLPILLERHDRASDTRTWLTSLALHILSTLETIPPSSGTCSIQPILFVTAGSELRFSSSLDSFDPATSDEKIARARRFVEGRLNAFMLRLPSAPLIRMLELVKEVWRRSDGVGVGGNRRGGGRDVFWMDVMVERGWQTLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9B6</accession>
    <name>A0A6A6P9B6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine containing phosphotransmitter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_280726</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9B6"/>
    <dbReference type="OrthoDB" id="1673781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043424">
        <property type="term" value="F:protein histidine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.160:FF:000007">
        <property type="entry name" value="Multistep phosphorelay regulator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045871">
        <property type="entry name" value="AHP1-5/YPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242:SF52">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="Histidine-containing phosphotransfer domain, HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="3">
        <location>
            <begin position="24"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="136" mass="15912" checksum="17610CAF05B082C5" modified="2020-06-17" version="1">MLEQSDSIDTTTFEQILEMDDDDDRDFSKSIVYDYFQQAQSTFTKMDTSLDKRDFPQLSDLGHFLKGSSATLGLTKLKDSCEKIQHYGKRKDETGTRDESDEELLLGRLRSTIDDAKQEFNEIERLLRRFYRDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9L8</accession>
    <name>A0A6A6P9L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_171298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9L8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="218" mass="23080" checksum="D5DEE4490899485B" modified="2020-06-17" version="1">MAPALRKDAHATPTLQLLRHRLIHLLMADPRGDRKGAALEPVLQPALDPAILAHLVPTRQLPHGRQALERLLQQDLVLAPDLGDGGAGGRLADLGQHEQAADLEGRVLEVGADAAHEAGRVVGVRQVEAAAGRLDQVEGSPHGHGAGQPREEADPAPLHRFLGDEEGDAPAGFLADGAHHDEGVDELGRSGRAIVSCCVPFLLSMPLCLFGTKRCYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Z6</accession>
    <name>A0A6A6P9Z6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_280832</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Z6"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000031">
        <property type="entry name" value="Probable PRS4-ribose-phosphate pyrophosphokinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000005">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002320">
        <property type="entry name" value="PRK01259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="12">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="34933" checksum="024FCC45953603F8" modified="2020-06-17" version="1">MATNSIKLLTGNSHPTLARLVADRLGIELTKILVLQYSNQETSVTIGESVRDEDVFILQSTAPGDINDGLMELLIMINACKTASARRITAVIPNFPYARQDKKDKSRAPITAKLMANMLQTAGCNHVITMDLHASQIQGFFNVPVDNLYAEPSTLRWIRENLNVKDCVIVSPDAGGAKRATSIADGLDLGFALIHKERARPNEVSKMVLVGDVKDRIAIIVDDMADTCGTLVKAADVVIQHGAKEAIAIVTHGILSGNAIEALNNSKLKKIVVTNTVPHEEKKERCPRLETIDISPTLAEACRRTHNGESVSFLFKHAPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA40</accession>
    <name>A0A6A6PA40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_418747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA40"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="185" mass="19919" checksum="2619871C4AD3C00B" modified="2020-06-17" version="1" fragment="single">MLQGNGRRFGLSRRRGAGGRASPRETVLSRNVGAAPCRSRDVEVHARHQPLAALPASWLAALGPSMHRAERHGRFFRPLPSASDRRPALAQSRRLCALCYKLPALLLRPSGNPNAEDPCGALPHHLIDSPRKISPTFPDNFAFLAAGAAPAYSLHPAGFFSISPDAWMSKYSLDWACAPPGPAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAA8</accession>
    <name>A0A6A6PAA8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAA8"/>
    <dbReference type="OrthoDB" id="2430277at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="9407" checksum="D7CF65C506E4ECCA" modified="2020-06-17" version="1" fragment="single">MLDPSAYTLTNGGGGGAGGHDGRSRSGSRASPLGSPGPGGGAGAGARPPPPRVSDSRWKFQDEGLFPKPREFGGGVKRYRAGRGSSVPLNLGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAG0</accession>
    <name>A0A6A6PAG0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_279419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAG0"/>
    <dbReference type="OrthoDB" id="5426165at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40623">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40623:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="375" mass="40081" checksum="9D06FC44D69FEF79" modified="2020-06-17" version="1">MGSWFFMPWPLWAKLSFVVVIIAGSIKLWFTNRKVKKYAAVHAPAQARTPEMLEAQHQEPEVKVPFGIRAIESGIEVDGVWISKTNTPAPSSRASRASSTLSLSTTNQLESGYSSVQDKRSRASSMAPSSVFDRAVSAERITTNNGSRASSPGPSRYVVSPYHRLSHVAETGQLTPRVRRPNFSTDLASIMTTATEPAPQATKARPTNSPPAESPAASPSGSDCPQTPTVSLVSTGLLTHDAHPANEARQAIPLLETYQPSTTAEESSRDEEEQMTPNVPPAAFMPPSTRDSQVLRKVNSGFEILKPGTLKVDLPPMDADERGSSSGKKLRKKNKQGSHHRRGGVDGYGNGGGSGKSDAPSLSSDGAPPSIKEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAJ1</accession>
    <name>A0A6A6PAJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Formamidopyrimidine-DNA glycosylase N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_333817</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAJ1"/>
    <dbReference type="OrthoDB" id="444592at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08972">
        <property type="entry name" value="PF_Nei_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000009">
        <property type="entry name" value="Formamidopyrimidine-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="entry name" value="MutM-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="FPG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="H2TH_FPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993:SF9">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="N-terminal domain of MutM-like DNA repair proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formamidopyrimidine-DNA glycosylase catalytic" evidence="11">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="285"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="384" mass="42757" checksum="F67CC80A8951EFEA" modified="2020-06-17" version="1">MPEISEVARIVHYLKKNLVGKTIKSVQVQEDEIIYGKAGTTASAFKTAMTGKTVVDARQQGKYFWLVMSKPPHPLMHFGMTGWIKLSNEDTTYYRPSKAEQEEAWPPRFWKFVLDFGDGQAAFVDKRRLGRIRLVDAKAEDMRKTTPLKENGPDPVIDKDILTLDWLSKKLRSKKVPIKALLLDQANISGIGNWVGDETLYQAKIHPEQYSNTLSDAQIKQLHLAIMHVCTSAVGVLGKKEDFPDGWLMKYLLGDEKKDKSRLPSGEKIIYLKVGGRTSAVVPSVQKKTGDVAGDFSEDEEEEEPKPKKAVNGTAAGKKGRKKKQVDEDEDDELFEESDEQPPAKKQKGNAKATKGKTSTAKPASEPGKAVEATGKRRSGRFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAX3</accession>
    <name>A0A6A6PAX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAX3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="9129" checksum="3A5B08D973D7B1E3" modified="2020-06-17" version="1">MKKGFFLIAAARASTLCLGHVLITVRTYLPRACWRCLQATFCGHGSYPRGCEKDIFCSCLIKINTCDSAIFVSSYRNRPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB57</accession>
    <name>A0A6A6PB57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_140913</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB57"/>
    <dbReference type="OrthoDB" id="3251668at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF78">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="457"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="162"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="335"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="619"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="623"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="660"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="699" mass="76434" checksum="ECD85A30EAA97E42" modified="2020-06-17" version="1">MEYGTTAVGALGQHHRPQSQTPLRQHPQHYRHDGSNASGVVPPAGAAPVTSSSATPTSQLQQRQHALPTASAAGPPHWTVTSTPNPPALAVPASGSRSRSSKDSSNTSDVYYYVYSLDEFEDHLRAYLSCPPEDPEHAACHINFWCGATFVVDISGYGAGGGGGTVQQRPQSGGSGNGQAQGEREGQNDSAEHAEEARNTAGDQSGGGGMSQQLTVLEAFAETPEPSVRQRRQRAIGKVIVDAVERVDGFRYSFHNNWLSREDNAFRFSYFCNDSLLNKGRKNNHKNQISGGDPTKRSKKPVYDCRGLIAVKFSETKQALEVIYKHIPLHQTYEERAPIPRKDSKRRQWLEQHEPDKLSKKRKSLPPDDLEKQKGLMKPNSFKTKDESMGSAEHELRMSSLQSLLTLIQRDDGSVEEHQQSPTLGSFESPNAQAPLTAISTNKSNNNNSNAKNHGRTCDVCREKRIRCDATRPRCKQCVDRGRPCTYNRASRVDAPELIESGFVAINSSNAPTGSSELVLTKSELDEARGEIEGLKARLAEAESRVEALDGEKATLATNNAHLEKHNSKLCSEKTALEAQLLQLDTEKTTLAEQLQQVQAQLEEAKAKVQQAQQQAQAHGTAAGLGSGGDQTGGLSGYGRGMERDGGHSRRSSTSTQQSNLFNQQMPWSPTSYAYSSQQMQFPQQNSWGYTGQGSSIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBE0</accession>
    <name>A0A6A6PBE0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_279574</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBE0"/>
    <dbReference type="OrthoDB" id="2399539at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="76"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="654"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="663"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="784" mass="86942" checksum="3FA5AB73514B2AB9" modified="2020-06-17" version="1">MNQPPSAPGRSNQACKRCYNRKKKCDRVLPRCTGCQHANVQCSFEEQQEESGVFYISYVRGLEQRVAELEQQSKAFQSVPSSVTDPSSPASRSGQNGPFLHSSGSPSSSHRAAARPVREADSQDSRSVAPDNDQQAGDLLAAEVKALSLEATAERYLGSSSGMSFARLTQAVLRRLKPDQYPFSFELPSAGRFERQDPLDFSTLESPVLDPPPPELPKPIGIVPEYPSSLPLESHAYRLADFYWAHSHTLYPFVRKMWFMECLQLMYNDSSHPAVQSPFWLYTMWMVLAIGSTSLSSVMVVEEAESIQYFNNAMLYFENALEHGNISALSAILLQVSYSFFNQVGPNTWYLVGAGVRLAIGMGLHAAPTKEVLELPLEEQEFRKRLFYSLYMMDRVVSISLGRPFGIRDEDIEVDTFSSEVDDPAPQTVDPTCLHRPLKASTLAVPLHIVNLRRIAGRIFDKVYSNKGRELQQSEKDAILQDIHGQLIHWRRTMPFPLPQSGTFRVPHLTTAWFDLNYYNHVIMLYRPSPLCPVLTLEKVVFIAEASSMSIRQMAVMHREQSFAFNWLNLFTLFTTTLTLIYSITAQPEPLGTYLQRTSALDDLGTAVNLLQTFGVKFPSALKCRDIVKDVTERLQSHQSEAAIRERLAQGLSGDASKEGILNSPQTRSTSSGPSADLSPSQSAATSYPSYTTGNNLYDGLQNQVRGMQAPPPALAGDDDEGANPEQSPAQPMETGLPTNLQLPALPNPFGNVTAQFMAAGLGTSADVDMDSDFWNALDGTFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCF0</accession>
    <name>A0A6A6PCF0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_91478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCF0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="170" mass="18639" checksum="DCBF06AF5C091466" modified="2020-06-17" version="1">MHRRARPPYLAPRSPARCISVYRLLKARRSPPWPDATACRERLCLCVWLPPAAARSAWTGMSMHREVFSMGVWRQNGPQQFSTTIATDRQGTSLCSEDPCLPLISQPSLMEGPFYNGANSSRPASDPGLKTTEDGPPPTMYDARFSIPGLGSEAETISFITAAQAGDVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCM9</accession>
    <name>A0A6A6PCM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_376600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCM9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="143" mass="14934" checksum="6222DBA89B08694D" modified="2020-06-17" version="1">MAGESLKVRGSGGVSGMVVVVLVLVPVPLLLWSVYGESTGTRERRWYNARTRRLMATLSSPQQRSRRLDRAPISVGEVVRAAGSATAAATTAAAAVLLRIWLIAERPASLSTRSTATAAAAGQQGSRRNADNTGVADIDGSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCZ9</accession>
    <name>A0A6A6PCZ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Belong to Rho subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_383567</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCZ9"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000329">
        <property type="entry name" value="GTP-binding protein rhoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="193" mass="21850" checksum="63B9976BBF73C3EB" modified="2020-06-17" version="1">MSAEIRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAIDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRYDQKTIEELHKTSQKPVTPEQAEDVRKKIGAQKYLECSAKTNEGVREVFEHATRAALLTRKKKEKKCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD82</accession>
    <name>A0A6A6PD82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Asparagine-linked glycosylation protein 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_368864</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Heterodimer with ALG13 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ALG14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD82"/>
    <dbReference type="OrthoDB" id="17098at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025430589" description="UDP-N-acetylglucosamine transferase subunit ALG14" evidence="12">
        <location>
            <begin position="27"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="162"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="356" mass="37418" checksum="D19EC1DB66901AE2" modified="2020-06-17" version="1">MLLTPLLLSALLLLLPATLFLRRSNASRRPRSARRRRRQRRRAPGTPTHLCIALGSGGHTAEMLAMLAALDPRRWTYRTWVVSSGDGVSAARALEFEAGLAARWAPLPADACGRPCVGPASCAVRVVPRARRVHQPLWSAPASALCCLAACVNVLLAVPRPRPPASSQTAGGGGGGGSRNDDKPPARSRDADDDDDDDDDDGDRAHAAPNAATPLGPPDLVLTNGPGTGVVLVLAALVVRAAQRICLALRVPPPVANHYFRVPAVRLRRSSAAGDPAADPRLPRTVFVESLARVKGLSLSGRLLLGVVDRFVVQWEGLAAELEAQDGRVGGGIVPGWALELFGGRGGDVEYGGLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD97</accession>
    <name>A0A6A6PD97_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_389154</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD97"/>
    <dbReference type="OrthoDB" id="10257567at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="702"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Cux N-terminal" evidence="14">
        <location>
            <begin position="19"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="13">
        <location>
            <begin position="445"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="494"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="423"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="558"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="742" mass="80705" checksum="66442BCC89C82826" modified="2020-06-17" version="1">MSSTPPEGDAPAASESAAEDNKFQTAIAAWRNVDLSSLIPQLDTAASDLVTHQRDALTQRKDLAQKTKDFKKLDDTSKLGEIKGLLKSYQTFIDLLTNQSKAVSTAFFQAYTPLSEAPDPYPLLEASVDALISSSETVPKLADENAHLQRTVAKLTTQLDDTEQKLEKERTARQALEEERESKVKDIEASWERVLTEKEDNWAAKERSLEDKVENQDRLLKELKASYEVSQRLGQGNEGDAAAAAGTATAAELEIVSSELDKATMRLAEVEARNEQLRFELAQSASVSQTQEQASSSVEDDPAFLRLQSENGSLRRKLDAAKFEKDSERRKLEGDMRGLEREIGGLRKERDGLRERVQKWGDYESVKRELEVLKSIEFATGDDDDHLDDAPTADADADAQQNGATSKGDKGGETLEQLLLARNKKLSNELTVLRVSHQDLQQRLETLQEELSSANMDLEKSRSLTATLENDLLRVQQEAANSFGGGANMSSAMSVAPSRYPQSSYGGRRAGGGRPSSPTSSIISGFDPHRAGGGDGGDHHHQPMGGGSGILPMVTAQRDRFKKRNTELEAELAKTHQTVSSLRSEIAALQRDNLNLYEKTRYISTYSRGGAGQHPGAAYSSANDTAGGGASATAISIGGGTSASPVSADSRYRSAYESHLSPFAAFRGRESARALRRMPLPERVLLRLTRAVLASRLSRNLFAAYCLALHLLVLGMLFYWGGREVDSAASGLGEAAAACIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDN2</accession>
    <name>A0A6A6PDN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_368225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDN2"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="20965" checksum="21A867B8FF3AE38A" modified="2020-06-17" version="1">MATRNVVLAIVALGTFALIWNHSSIAASFPMSAATTDSAAAPAVADLEFSLAQSSAEPTKLKVTLTNTHASSTMTILDWNTPLDPLAPNLGVVHIVNSETGKEVEIPRIMVNRKMPPPRVDLVELAPGQSETREILLEGPRVSLEKGTRYEVNVSGNYMAVWASPSEQVGETELNQLSGGTAMSGQYESEKVAFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDY0</accession>
    <name>A0A6A6PDY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Snf7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_330712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDY0"/>
    <dbReference type="OrthoDB" id="10252926at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="221" mass="25401" checksum="3413CABE07F9B9B0" modified="2020-06-17" version="1">MNIVEWAFGKRMTPAERLRKHQRALEKTQRELDRERVKLENQEKKLVQDIKKSAKNGQTGPLRIQAKDLVRTRRYIQKFYQMRTQLQAISLRIQTVRSNEQMMQSMKGATSLLGSMNRQMNLPALQRIAMEFERENDIMDQRQEMMDDAIDDVTGLEDEEESEEVVNQVLDEIGIDLGQALGETPSGIQKAAEPETRVAQAVGGGDPGDDDLEARFNNLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE87</accession>
    <name>A0A6A6PE87_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-P-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_277025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE87"/>
    <dbReference type="OrthoDB" id="10000533at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2462059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="32905" checksum="BFC43E4B76A87D39" modified="2020-06-17" version="1">MVTVAVAGGSGGLGLIIAHSILDSKKHKVVVLSRKENPELSALGVDVRPVDYNDLSSLIAALNGVHTVISTIAVPNKALADSQIALINAAVAAGVKRFAPSEFTISSYDSIELYAPKTAVWDAVVASGLEYTRFTCGLFHNFWAAGTPKGEKEALAGMPAWNFIINVKAGTADIPGDGGVKIAVIDTRDVARFVTASLDLPKWDEELGMLGEYASWNELVDKAEKATGRKFLRRYTTRQELVKLAEDPEKRFYNQFRIAMVDQKFTVPPTLNEKFPEIRPMSTQDFLDNAWAGVELPPPAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEB2</accession>
    <name>A0A6A6PEB2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_330481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GLYK kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEB2"/>
    <dbReference type="OrthoDB" id="347435at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001691">
        <property type="entry name" value="Probable ATP-dependent kinase TDA10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2462107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="305" mass="34346" checksum="A5D0B1DCD0C7A516" modified="2020-06-17" version="1">MPEIVDDKSPHCIPFIVERIKAHQNRFKDQSDVPPFFLGINGVQGAGKSTLVSALSQTLESPPHSLPTAVLSIDDLYLTHADQRKLASDHPSNPLIQHRGEPGTHDIRLGAYVLDALAQGRQVKLPRYEKAAFDGEGDRADPATWAEVNGPGQPRIQVVVFEGWCVAFRPLTGEALRERWEDSRKRAAEGVESVMARHGLENLAWVNEALKAYDTFTDKLDALIHIDAEDTKFVYRWRLEQEAELRRLKGKGMTNEQVVKFVDGYYPAYELFTDTLRVGVFGSEHGKQLRLIVGEDRKVKKVLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PED5</accession>
    <name>A0A6A6PED5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_418240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PED5"/>
    <dbReference type="OrthoDB" id="4188028at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="540" mass="60358" checksum="E8403E13FFBECB21" modified="2020-06-17" version="1">MRKRKEDAPSASPISDSEKTSKTTSPETRLGSSNKRGAQTPSSKPARLQPSEPLHMTTRAASRAVSNSAASSVASGDSRRNSLAEVSSESIDSVTGERSKSRRLSLRSDASHDSQNTPHSTAESPTDQKESELLTELREDARQTRKRKRSPEEPTSNGVNQSESLINGLENGLAKERKEKENGELLQPPLKRRGGRRSILTQDGTPAASADATPIPGTPNSTINLPPGHSQSGAETPNMEQPAKAVKRLPGRRRAPNPNVNIEADLRRQLHLKMGYRAVAKVLKPILDELAQRTLNDLENDPQLYKQYEEYDEIQAELRDRLGDRLTTVENQRKHKVGTLSRVMIAQEEMIRAEYINRVLQVQEDLLIHCQTQLLEIQRAYLREQDDDATDDEGNLVPRPRKASTKKQQQPAEVLGWKYDSRSRFYVEADQIWKDDHFRRTFQNDQSQFIDDDEEMDDGAKASVLDTTNFATCDGRFRDVRHAEYNMLQLAKASEDVGGDWIATSSRFVDGRASGIGDPEAFEANSQTADYLSEVVSDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEG2</accession>
    <name>A0A6A6PEG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_390063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEG2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025619252" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16836" checksum="744FC8595F2081FD" modified="2020-06-17" version="1">MSHHALPQVASVWLRRLRLVSAVSVSLAPAPANQTDHHDPERQEMVVRNSSECRNDDALVSGTGQWRRRQQGSSARYRAQGRLDASFYSWRDAPPHIRYAGQVIVGDWDSHWGQHGRKAALDKRQWLCSALLRLQHRDSSPSSHQVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEH1</accession>
    <name>A0A6A6PEH1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Synaptobrevin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_330802</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the USE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEH1"/>
    <dbReference type="OrthoDB" id="3231855at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019150">
        <property type="entry name" value="Vesicle_transport_protein_Use1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050">
        <property type="entry name" value="USE1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050:SF7">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN USE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09753">
        <property type="entry name" value="Use1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="107"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2462222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33126" checksum="BF132FB71D7ED72D" modified="2020-06-17" version="1">MARTSPADADAAVVSLARLLAHLEGSVLSPDADPSLRSSPYERSKVDANLEYARTLLLRLEHESAGIKDLGKKQAVLADIQTKRQVIKQLNQRLYELKQLDLDLEHTDESDSETDELDDETAPSYGPRLHHATSGIDSENPPGEGAISQSAAAEVTSTLRSRKGQENSIDSAAATGTDLFAGKRPKSPTSDDPAERSEKLLSHNRMEQDALTSSMLKMAQALKVQSVQFGESLEAEKGVLDRAGKGLDKNTTGMEAAERRMGTLRRMTEGKGWWGRMMLYAWIAGLWVLLLVIVFVLPKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEK6</accession>
    <name>A0A6A6PEK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptide hydrolase</fullName>
            <ecNumber evidence="13">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_331354</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M28 family. M28A subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="13"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEK6"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03876">
        <property type="entry name" value="M28_SGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000054">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041756">
        <property type="entry name" value="M28_SGAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 13" id="KW-0732">Signal</keyword>
    <keyword evidence="11 13" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025716800" description="Peptide hydrolase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="14">
        <location>
            <begin position="139"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="254"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2462418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="522" mass="54987" checksum="97DE08A616960AF2" modified="2020-06-17" version="1">MRTAQGVALVSLAAGVASARSIKPVEQLAERDCDTCEDLPLVSADALISDISEDALLEKSQTLEDFAYSYPDRNRLAGSEAHNDTVDFLYDTLVALDYYDVYKQPFNLSASMGGTGDFFVNEVNQSALIMDFSPNGTVAATVVPVDNLGCDPSDYPEEVDGAIALISRGECEFGVKSALAGAAGALAAVIYNNVPGELQGTLGEPPGRAGIGDYVATVGIDMETGEDLVEQASEGDLEGIVDVLSYYIKAFTNNVIAQSKCGDQDDLLMLGAHTDSVAAGPGINDNGSGSIGILEVAIQLAKYGVNNAVRFGWWSGEEEGLLGSTYYVSQLTDEEIAKIRLYLNFDMIASPNYVYGIYDGDGDAFNMSGPAGSAEAEALFEDFFAERDIPSVPMEFSGRSDYGPFIDVGVAAGGLFTGAEVEKTAAEAADIGGEAGVAYDPCYHSACDNVTNLAMDAFVVDTEAIASAVATYALSWESLPPPSNATAKTRKARRDLVRSAPGLSMAELGKRHGFFGGKKHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF09</accession>
    <name>A0A6A6PF09_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF09"/>
    <dbReference type="OrthoDB" id="2898509at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF2">
        <property type="entry name" value="KETOREDUCTASE (KR) DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="339" mass="36080" checksum="65B02C912DD8B3A0" modified="2020-06-17" version="1">MVSLSEVAAHNASLKGLGAGLVGVFVGGTSGIGESTARAFVKHTAAPKVYLIGRDETKASSIIGEFSKLNPEGQVRFIKSDVSLLRNVDSVCDQIKSQEDKINLLFLSSGVLKTGGRDETAEGLDKKFSLHYFSRQRFTMNLLPLLSRASGVNNQPARVISVLGAGHEARLNAPDDLDLAKPGNYTMRSVAVHSTTMTSLAVEALAAQNPDVAFIHDSPGVVRTALDREMTWWGKAGTAVLFILAKPWMVPVEESGERHLYLGTSPRFPAKSGKGGQENVQPAVGSDGITGSGAYIVSADQSPTGNKKVLDEYRKAGMPAKVWDRTVEVMEKATGKVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL26</accession>
    <name>A0A6A6NL26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_359431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL26"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="20285" checksum="4B748CF21F5D8E1E" modified="2020-06-17" version="1">MRCRPGMVSLWRPALWIYRVRQRYPRACASAGASLHHQASSKLGIRQEAVHGHDGLSPLLGCASFSIVSRRVLLTHRFFPLQCVYTSAPTLAPPRSLAGGISQPFLSLRALSHDVKHIPSLSAVIHHSVRISLAPYSLISPLCMPSPNFRYMTAPSEPFPPCPSSTSCSTTATTPPTSTILATSCPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLG3</accession>
    <name>A0A6A6NLG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_375505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLG3"/>
    <dbReference type="OrthoDB" id="3865154at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF3">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="237" mass="27373" checksum="3FB0ED61772DD101" modified="2020-06-17" version="1">MALGSVGKLDEEDELQTPDSVRRKIRRFCNAWERQHDLSIPLEVKRSMVPAKNHVKLHELLWFDDYHGYVHNRYRVDDANLVNSHCFTFARLKELYQAKHRDLVLLVGWKYGEPELKLKIKRRECKRKHKKQPEHIIPEKMSPKLGPPPLYSQPTLLWLATFISSKAIKGNPTLEEVLGLVPPPGRKHGVIPWEEDMLDKPVFPNTAKRAGFCDGMGFHALRPGVLVKVVDDGYCIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN2</accession>
    <name>A0A6A6NLN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable alpha/beta-glucosidase agdC</fullName>
            <ecNumber evidence="5">3.2.1.20</ecNumber>
            <ecNumber evidence="6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDY21DRAFT_294758</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="5"/>
    <dbReference type="EC" id="3.2.1.21" evidence="6"/>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLN2"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF67">
        <property type="entry name" value="ALPHA_BETA-GLUCOSIDASE AGDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 19" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025445151" description="Probable alpha/beta-glucosidase agdC" evidence="19">
        <location>
            <begin position="17"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="21">
        <location>
            <begin position="109"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="20">
        <location>
            <begin position="280"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="22">
        <location>
            <begin position="728"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="456"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF2452397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="948" mass="105494" checksum="E4C22851814D35C8" modified="2020-06-17" version="1">MLVPAGIALYLASTSAAPTNNIDVLDRRQLPPTDADVDGCPGYTASNVVQSGSSFSADLTLAGDACNAYGDDIEELTLSVTYETDKRLHVLITDAAEEAYRVPTSVFPRPESQDCSPEESDLEFDLVEDPFSFSVKRRHSGEVLFDSSVAPLVFEDQYLRLRTALPEDPNLYGLGEHADNFRLNTTNYTRTLWSRDSYGIPEGTNLYGNHPVYFDHRGENGTHGVFMLASNGMDVKINRTEEEGQYLEYNIIGGVLDLYYLAGDSPSDVSREYAGVAGVPAMQSYWTLGFHNCRYGYRDFYAVAEAIYNYSAAGIPLETMWTDIDYMYERYVFTTDPERFPVPRMRDIVDYLHEHDQHYIVMVDPAVAYQDYHTFNHGVDEDVFMKFDNGTIYKGVVWPGPSAFPDWFHPNTQGFWNLEFANFFDPATGIDIDGLWIDMNEAANFCPFPCLNPNETAEENGNPPERPFVRSQPRPIPGFPPEFQPGASDAPPDSTPYNDPWLAPPGATGNDPPAKHRRQLEIDLSAPLDTPVGIPGRDLLAPPYRIGNEATYQDYGGLSNMTIRTDLHHYNGLAELDTHNLYGTMMSETSRGAMLERRPAVRPLVITRSTFAGIGHWVGKWLGDNLSTWEKYRQSIQGMLDFSALYQVPMVGSDVCGFGNNATETLCARWAMLGAFYPFYRDHNQDNALPQEFYIWESVTEAAKKAIDVRYRLLDYFYTAMYDQSVDGSPSLLPMYFLYPGDANTFANALQFFYGPAMLVSPVTEENATSVEIYLPDDVFYDFYTHEVVQGAGASLNLTDVGFTDIPLHVRGGCVVPLRTESGMTTKEVRTKPFELLVAPGRDGVATGSLYLDDGDSIVQDATSYVEFAFANGCLTASGSFDYTAEGAEIAKFTVLGVEAGPSRVWVEMGGEAEDAMQECAYEFDGAKGELTVTARVMLTGGFSLKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLV1</accession>
    <name>A0A6A6NLV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositolphosphotransferase Aur1/Ipt1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_294379</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLV1"/>
    <dbReference type="OrthoDB" id="2566866at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF7">
        <property type="entry name" value="PA-PHOSPHATASE RELATED-FAMILY PROTEIN DDB_G0268928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="7">
        <location>
            <begin position="151"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="7">
        <location>
            <begin position="247"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="7">
        <location>
            <begin position="373"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="480" mass="53869" checksum="733FEF32E5D5A9E2" modified="2020-06-17" version="1">MGAGAFIEPLIVVTLLFGGTWVNRNRGYRFRPWAPSYKDDSRSVSSSSSGRSSPITPGEGNGLLSPSLLPAQEPGWRKRELRIWKWKTYARSPNTRVFKDTLLSRLLRKFPFLVEAWYWALIYWVYQLGRAFTAVHLSDATVDTARKHALQVIHVEQRLHMFIELPIQRFFLRHPFLLTWTNRVYSFIHIPGTILFLVWLYHFTTTARQRQQQQRQLNASLPQHWRKDGKIDGQQQPHSMIPSPAGPRLYEARRRTMAVCNLLAFVVFTLWPCMPPRLLSDERVPGAEGAEARSYGFVDTVHGNGGEGSVWTHNKFCNQYAAMPSLHFGYSLLIGLTIVTIPLPPAHRRPLRLSLPLPCLLQTPIPLRLPSARRAVLLAVGTAYPAVILAAIVATANHFVLDAVAGALVCGLAWCANGVLLNLLWLEDWFLWVVRIHKPDVVARWGVGGGAVCEGEDGTSEESDEDGGWGKGKGKGALGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM15</accession>
    <name>A0A6A6NM15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_294609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM15"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001666">
        <property type="entry name" value="MDS1 and EVI1 complex locus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001732">
        <property type="entry name" value="Zgc:162936"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="91" mass="10681" checksum="46C65379CE724812" modified="2020-06-17" version="1" fragment="single">MPGYAQGFQKSASPKRHKCPYCTTYFTRHHNLKSHLLTHSQEKPYECPTCQARFRRLHDLKRHTKLHTGERPHTCPKCGRKFARGDALARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMQ4</accession>
    <name>A0A6A6NMQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMQ4"/>
    <dbReference type="OrthoDB" id="5406216at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031452">
        <property type="entry name" value="Kre1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17056">
        <property type="entry name" value="KRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="17087" checksum="0C8A910095BB267C" modified="2020-06-17" version="1">MAVHPAPLPAPPAISNSTIARQTTTAEPSKAPAANAPLPTAHPLGDLELREIVADPAAAATNQAQAPTVTTAWIETELADGTHTWVEIVFTQTFAPVLDQLPSPAAGSVGMGSLTGEVGVVKTAVPEEAGAARVRGGGGGGGWERGARWPRWRVGGGVVAAVLGAGVVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMR5</accession>
    <name>A0A6A6NMR5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7923 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_148102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMR5"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7923" evidence="2">
        <location>
            <begin position="84"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="412" mass="46386" checksum="50978859A1166FEE" modified="2020-06-17" version="1">MITFAMNSPRMHGMMLQYDSYRTEVDRFTEVDTQRQQLIVRLVEALESAQNEIRKCQLDLQNETEARRRFQEQAELMDGRFRQMERRPYIVVLIDADADGYTFHDDFLMEESKGGEAAADELLARIRGSLPTGLFERADMDIVVKAFANIDGMAQALVRDGRLSDTRSFRAFVSGFTSRLPFFDFVDVGPGKERADQKIRENLRFHIDSWQCKHVVLGCCHDSGYAAFLGQFVANPAALNRISLLEGSTPCHPEIAKLALNQIGPFDTLFSTPPSRSPKLVTYAKISSGGSSGSSSGGSSPPSPTKSIVLRAAQTGRERFGPILRDANGRRRDRELKNPDPAVLGKLKSLNLCNWKFLRGNCDLESCTRNHNFRDLTDAEGDALWYLARQGRCWKVRRGDDCDDPKCIYGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMT4</accession>
    <name>A0A6A6NMT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_424935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMT4"/>
    <dbReference type="OrthoDB" id="2192830at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF8">
        <property type="entry name" value="LD22649P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="165"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="644" mass="64695" checksum="544D755D537BE9EC" modified="2020-06-17" version="1">MSASAGASDASLRPRPRRHVSGPAPGAAADASARSAASSPSRAATPSQSRPLSRAASPMPAAHPSRGGAGGAAGGRSVSAGVGGGSTREREEMVRARKRADLLAGAVRDEVSEATDKAGRYKRRNSDLLRPDDLVGSGLSSSSVPPDVTRAAAEGDGGGGDALVYVHHVKRGDTMAGVCIRYGCNQTVLRKANRMWPNDTVQVRRTLVIPVDACTVKGRRVDGPHEHRGPEKKALDDNGDVAMMAQEEEDLLLAGGAGAEPSPSSPPRRPTTNGWHKGAAGSSSAPQDARPRSSSSMATNTTAAADPDPPWKHDSWVLLPADEPPVAADAPSSSSPPPLTEIARMPRRALGFFPTPARRKSASRASVSLEESSAASTPAPSSSLDLPRASLASDSAAASPTSSPLQRAQHHQHKHSHSTLSRASSSASSAAAATAATAHLSARLHGPGGVGTMGRNVRGPGPQGPDKFSRMLARHLPSVEPPPGVEAFTPWWTGAGGAAALEGGGAAAAGPGPAAGVGVAGALAELETLGGAVEGWVRRVVARDWGAAGSSGDGAGPAPAPARGRAPRAESGAPAAAEAAASLAGGRVARNAHAGPAVVRNPGVVGLGAGAGGGDLIELADAFEYMEATRAVVLVGGFRIMDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNA3</accession>
    <name>A0A6A6NNA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_143702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNA3"/>
    <dbReference type="OrthoDB" id="70588at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008277">
        <property type="term" value="P:regulation of G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02987">
        <property type="entry name" value="Phd_like_Phd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001200">
        <property type="entry name" value="Phosducin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051499">
        <property type="entry name" value="Phosducin-like_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052:SF1">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="3">
        <location>
            <begin position="139"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="280" mass="31476" checksum="E8B9281F70DA81D2" modified="2020-06-17" version="1">MTSAQDEFNELFREKGRRTGHPEDDSDNDNHHHNNNRERETFFEKDSDAGDDEDDTHPSSSANTSKMRSRYYLPKLRSEANTGPKGVIADAQAFEAAKRNAHKLPFMSSGKKEARTTPPPSSLDNNDKGGSFLDGERSSDDEDAFLARWRANRLKELSRSRNSSPANRRRYGSLLTVDAEGFLDAIEKVQRDTIVVVFIYDDMSDISDMVEDSLRLLARRHSTTRFVKLHYEEAEMEVAGVPAIIAYRGGEKFAGLVPLVDEMPDDAGLDPAGLEHVLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNB1</accession>
    <name>A0A6A6NNB1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_424661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNB1"/>
    <dbReference type="OrthoDB" id="5416037at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502:SF4">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="3">
        <location>
            <begin position="115"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="387" mass="43705" checksum="7EAF842B96ACD6A5" modified="2020-06-17" version="1">MDRCETTEAYGPSPPQRAPNVAPTWGIEDTRTVAHQSAQTRSPHTAQKNPPTNWETYSSQVQFIPNSGSVPPPPNSFDSSGLAFGNRFVPGSSSFGAGHTNTEKILKGAWRTKGYPAFATFMGSSDDTFAVRRFAKLHARSILLLQNEIVVLERQLRDMDEKIYQNESDPEKANQSSLLNDKKHHPVRITLLWQLTSMLERYDKMVLRYSMLKSRPKAQKSTIRNLQGWLHNNEHAIEKSEAEFFTEKGDDLIELVPGAKSMLRRVFERLPTFKQWFRYREPRPGNYDFEYEPDGVIYFSNGCIEIFTFVIIMGMGLGMLLGPAWWLQKASSPDTRLFIISAFVPLFAVLLLLALPTPKPFETLAATAAYAAVLMVFMQLGVADSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNC1</accession>
    <name>A0A6A6NNC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNC1"/>
    <dbReference type="OrthoDB" id="544298at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013869">
        <property type="entry name" value="DUF1757"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38636:SF1">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38636">
        <property type="entry name" value="PROTEIN CBG20488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08560">
        <property type="entry name" value="DUF1757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="125" mass="13313" checksum="6E98E79DF12ACB86" modified="2020-06-17" version="1" fragment="single">MTSLFPHAAYEEDQPYARAILTTHVLRATFFLGSALGLASGTLTHLTLRFLGRPGASSPFLPRLVAHAGRGAVIGPAVGLLALAGRMRAREPIEWQDRAWRLQENAGQVRADRWTLGGAAVGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNE5</accession>
    <name>A0A6A6NNE5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_417508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNE5"/>
    <dbReference type="OrthoDB" id="3246050at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="2"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="253" mass="27813" checksum="2E7689D730F54647" modified="2020-06-17" version="1">MSKRTVFTTITPLPAELPRSTVLSVLHDHAEMIDLNPLVIDRFPVAPPETCPADEAHCTWYQITDKLSYLPGGLATGKVSYHAAFHDLPKGLQTHVYAPMGLEIREKWTLGGSLRGEAREPVELGLGAPADGLYLREDVDMRCNVLMTAFVRKTLRRAHGMLVDKMLAKARADAGSATASDTTASNTTASNTTSNTAHQQYQHQQYQHQHQQYPWDDKPLPGPPPAELGGQARFEMADPGPRARVPQGPVEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNK2</accession>
    <name>A0A6A6NNK2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNK2"/>
    <dbReference type="OrthoDB" id="3057168at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="49"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="590" mass="66028" checksum="6D5982A0B5BDF19B" modified="2020-06-17" version="1">MERELVLRPAPPRQSHDEVDRYEVDRFEFDRYDADRHGGRPRPPPPTHKRLIVCADGTWHNADDGMLNGELETPSNVARLSRAIKSVGDDGVPQIVYYQRGVGTRGNVVERVVSGVTGDGVRENILSAYSFLCNNWAPGDEMILTGFSRGAFTVRSVAGFVAVVGLLTKRGLRCLPEIFRDVQNRRNPDYRSKNPDVPFPDKPSANDPRYAEELESRGLTTLDVRIKAVAVWDTVGSLGVPRFSILTRFGLQSNESEETQFYDTKLSNCIEYAFQALALDERRSAYAPAVWEKPRGNRTVLRQVWFPGTHSNIGGGNDDQSLANITLAWMMAQLEPFLDMRMSFVLEMDDEMLQYYHSYGKRDRPWSFGMRSSVLILSTPPLGPSSSPSLSNPPSPPKGKIEDSLTGVFALGGGTTRTPGQYYAVDPLTERETTRPLRDTHEYIHPSARARLALRGPGPADKGRYDPPALDDWRLVVDYPDDGDGDGYDGGGAPPRPRPDVLWIARFPERNVSARILPESPLWGPEKALLARDPDVEAFVARPPEMGGRRRRGRRRGPAREGEGEEWRMVEDAEERRGGRRRGGYARSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNS2</accession>
    <name>A0A6A6NNS2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_293529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNS2"/>
    <dbReference type="OrthoDB" id="27198at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032182">
        <property type="term" value="F:ubiquitin-like protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="2">
        <location>
            <begin position="14"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="26077" checksum="20DC965CB0C64ECB" modified="2020-06-17" version="1" fragment="single">YYNGSSSTQQANTGLRNVLSKTFDHYREDPSNQPDTVGMMGMSKYLDELGVSIEDIGMLVVSEIVKCPSMGEMGRSGFVNGWTTQGAETIEKQRQVISRRRGNLGNGATFDVFKGIYKHTFAMAVQPPARAVPLENAVEFWRTLLSDDGWKWSTETTPWLDWWIEYLERDWKKSVNRDMWDQTLVFAQKARADEDMSFWDEMGAWPGVIDEFVSFVKEKREAGGPMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNZ6</accession>
    <name>A0A6A6NNZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_125464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNZ6"/>
    <dbReference type="OrthoDB" id="5296155at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="45947" checksum="F7BE8E7F49035035" modified="2020-06-17" version="1">MGWFLTSRNKPAPPSDDLPPQKRISTPAGQRLSVIMENANNAAPAPQVLKDKRASAASNMSGTRTHIRSNSRRNVIIEEESSSGSSGGYSYASAWSDASGNEKLADGAAVSGSAEGTVQNNQHVAKRGRRKKLCLIISLVIAVIIVIVLGVVLGLQMKNNSGSSGGSSSSSQSSNGSSDDNSNDDSDSNSHQTSTSTGSGPSPTSPYSSASSTSVSSDFPAGNYSMVTFLDTTLTDCTSVSDTWSCYPYTEYNDSPSRSMATFNWIISASTDNDDDFVITSTDNPFAIDFQNEPLSRQDTGSDTEHFRFQITIDKSVQPSSPLSTGDDDSTAATCFYNSTTFQAYLYTKIPRGYPDDTVAATPDAPGNFEAWPFRVRVEEVASGGSDNPNCYGMQDGAVDFGNLIDNEAAGLEEQDPTDLCSCLYKNWRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPB9</accession>
    <name>A0A6A6NPB9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPB9"/>
    <dbReference type="OrthoDB" id="5387995at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="775"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="820" mass="82383" checksum="CECE4BC90A25B4F1" modified="2020-06-17" version="1">MAFSSNFMASEEYHPPRPPDATTTTSSCDSSPAMDRKHHDQSSSPSCSSSERTDVPTATTTTRPTATTITPATSTRAGTAPAPSTAPEQAATSSPPVSLGSAFTFRVEPLDRELDFSPRLARVSGRRRWKRRRATARFDVSAGAGAGPSDPDAMDDDDDADRHEAEHNLGHGNDGDDDERAADDAADPRFRVSDSDAASASRRRHRRRQRRQRPPSPSSPASSNASSSSSSSSSSTDFPISDINALVSPTIWPRFAPANPLKRPRRVSDVDGAFDTAATSASTSASAATATSSGASPLPSVKKRRLRLGPLVTSRLSRPFSQPASHVVDRGSSKIAVWAKQRALGRGLLRKAAILNAVRNRDAAMASSTTISSAEPPPTAAATAAVRPSALGAPFTGTSQAHTPSPLSASAVPSPQINISAAPIFTGGSSSPPSFSGVPFRHSPHTQRAPPSAPVLAPTHPTHPFYPSGATARAPLSAGSPPVLAPSPTPAPLALSSLGSALAATTRGRSPPSSSMAAPSPAPSSSPQPPPPPPARQPLLPLPPSPLGLSNYDALDQDDGYVPGGTDGWFDDEPPPPLPPPGGPAAGAYCVWPGAADAAGAGAAGGSADAAAAAAATARARTRSVGRKSAPGSRAASPGARSGATTPVGAGAGARATRSPPPPAIYSDFNVLEPAESVLEDHDYIGAWDAEERVGMPGVEVVGGGAGGGWGRGSGAAAAAIWGVGFGGAGGGSGDERSGRAVGDASYGGSGGGGGGGGGAVGAFGGAVGVDASAGAEAEDVDVDVDMDEEEDEPWLGSGSGLVREKESQKESMFGNSSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPI9</accession>
    <name>A0A6A6NPI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_355837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPI9"/>
    <dbReference type="OrthoDB" id="3944834at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="20410" checksum="2DC80C918F1F7499" modified="2020-06-17" version="1">MESHASFYSVASPVGAPYPGTPSGPPPFPYQSDSGLASPTPSSTRSTPQPHDTRQHARSLSQQQWEEILRSKDCPQGLMADPCYISQVSTELERRARADEHIHQLPQHAQRETAEERERERRLSWAQQMIMTNPLLSAEVFCTMFRRHQEHLEREQQQQQQQQQQRQQHQRRAPCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPN3</accession>
    <name>A0A6A6NPN3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_293038</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001577">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001751">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="530"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="894"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="950"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1029"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1134"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="253"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="624"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="930"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1224"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1436"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1445"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1456" mass="163689" checksum="A8B6FEAB767C10DF" modified="2020-06-17" version="1" fragment="single">GCVQVISIAPTIVAVLALLIDCSRPLLKWRPQWLRNFASEAEGPPDELFGLINRKRWTQYTAALILLSATGLTLSLVSAFKPWSLVGLILTSPWFIVTLLLIKDRPVSTPGLLLPVYIVTLLVELIGLCNPPQPDRNADALGITKACVSFCTIIVILLMPLRDPNMQNDHIARPSMPPTDHLGSPEDNLSLWQFMTVSWMTPLIALGKSRKLNDEDVWLLPYEFWHRRLHERFREIRGTVIRRLLAANGIDLIITAILGIVESLANFSAPVLLQQLLRAIEDDKASKRVAIIYAAIILAVRLVACQSAVFSLWYCRRCYERSRGEMITMIYEKTLSRKFVGYEASKEQTPQTNGVENGSTFHPHLKRGRLERVRRSMSQVFRWWKRPTMKDNSAAGATDTKKSASMGKILNLMRNDVYEVAQRFWEFPNLITKPLAFVLSIALIWKLLGWPCLIGMLTVIIAQLINVALVRALLRWERLRRAVTDAKLQITSQFVEAIRHLRWYDWQYEWLVKILDSRHEELRLRLMTNLWHTAISTTNLFASAMFPVVAFYAYTAIGGYPLRVDIAFPALQLFSMLDVSLRELPNLITVLLNAAIAVGRIENFMEEPDKEELFLGAGSTETTLALKEASFYWPGFPNPVLEDVSVSFPVGLTVICGKVGEGKSSLLQAILGELDKPCGKVIHPDEMIGYCAQTPWLQSMSIRENILFNAPFEERRYKQVLEACALTPDLANFKHGDLSNIGENGIGLSGGQKSRVALARAIYSRARILLLDDPFAALDHSTAETIIRRLFQGPLMQDRTICLVTHRTELCFGIADQVIEVTERTTHVLDVSKLKSDKSALERVTSEPQDEMDAKALEEQNDAAVPEKFIEEEHRATGGVMASVYWQYIKAGKLTWWIILIAIFAIFRLNRIANYWFLKKWGEAYENPHQKSVSDVLDRLPSPETNVKPWLLGFFLIALIQSILYFFSELTLMIIIYTAGKRLFAEVMHRVSCATFRFYDVTPVGRLMNRLTSDIGTLDGNISAQLQNCAWYFIAWVSSIVVIASVTPLFLIFSIALTAWFIFIFFRFLPTSQSLRRLEMVSLTPLMSNFGALVEGLTTVRAFRAQPHFQDRVIRVTDAFQKMDHFYWSLQAWLMYRFDALSAFSTFALTLLALYDGLSPGLTAFVLTTAANFVSATHTLCKRYGQLQMDFVSVERVIELLHLEEEPAGSVDPPASWPAFGDDIVFENVTIRYAPHLDPSLSNLSFNIPGGSTVAVTGRTGSGKSTLALTLLATILPQPGGHIWIGNIDITQVNVHALRRRVTFVAQDPVLFPGTIRQNLDPINEHSDQECGDVLRRMLGPEWSLTSHIDGGGRNLSQGQRQLVGLGRAVLRRSPIVILDEATASIDRKTAMYIQQVLRDELKESTVITIAHRVEAVKDADYCIILENGRVKECGPARTGAERQSSGVSSSQASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQC7</accession>
    <name>A0A6A6NQC7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQC7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="57" mass="6769" checksum="3F7E780B9F3FE127" modified="2020-06-17" version="1">MRTPYGTSMDVPSNRRPRIIKATALGQVRHVAVHWLFSRCSFSYIRRQVPWILSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQG4</accession>
    <name>A0A6A6NQG4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cell wall biogenesis protein Ecm15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_291779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQG4"/>
    <dbReference type="OrthoDB" id="5587367at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051614">
        <property type="entry name" value="UPF0045_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00106">
        <property type="entry name" value="MTH1187 family thiamine-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777:SF1">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="MTH1187/YkoF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine-binding protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="121" mass="12923" checksum="37E521085C944B92" modified="2020-06-17" version="1">MTPVDLEALPTPPHCTADFCLVPLGTSSASVSNEIAAVQRLMKQSGLTYSLHSAGTTVEGPWDEVMRVIGQAHSMLHASGVTRCHTDIRVGSRTDKKESYVEKVKAVERLLAKGSEGTASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQU0</accession>
    <name>A0A6A6NQU0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_112345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQU0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="288" mass="29996" checksum="32639431F3CD9170" modified="2020-06-17" version="1">MVAVPVVMNDLLDVVAHAEAVEEPLSRRRVSTIPVRRFRRSDSTYLVRMPAVVKIAPAAHRPPRPLRQLEVRRALVLVPVRQPPVPVRAGRARARGPIQLGRRRARGRGRVGVRRRGRRRQGAARPRARDAVARAAARAGAHLGRDAAEEGRLGRGGRGRGGRARGSPGVPVAAAALRAREVLGGRVGRGGRRRGEAEGGRRGRGGAGGGGHGAVEGVAGREARGWHRGVGTGTHGGVGGGVVVAAVVVVVLVVGVTAVVVVVVGGVLRRGHAPGFCIAVGRTPQFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQX3</accession>
    <name>A0A6A6NQX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_355112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQX3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="44377" checksum="D50FB072C443B9D0" modified="2020-06-17" version="1">MSPTSSVADAAAASAPPGAPSEAHKGRQGRKAPSPYLPGPVVLGIPTFERDGRSVQLCPCTFSPDCGAQSPANWGKHEKGVHLKREEWVCELCRGEGKDQRYYRYNNLTQHLKKTHKVEGELPRDRFASWKRDVAGFERRSWDCGACQAYLSTWDERVLHVRMHIQESRGEMRWLVSERTTYGTVRDAEALSQASTVDVAMDASSPPGSPSPLDQHRARSRRARDRDPVVHNVESQLADIEEKLYALNHDVRALREEKEGVEREIEATVALLGQAASRANGRSRLLPLRKRPRREAGRDATCDAQPLREPAKRLVELNEHISRKVDEREGLRRQHAELLHRHYRPDDPRDYGLEMEVAEPSRPSVAPQGERAPVRRRQVRKAPAQVHNGPSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRS2</accession>
    <name>A0A6A6NRS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prion-inhibition and propagation-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_352810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRS2"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0034">Amyloid</keyword>
    <keyword evidence="3" id="KW-0640">Prion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prion-inhibition and propagation HeLo" evidence="2">
        <location>
            <begin position="6"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="606" mass="67812" checksum="CAC60B46CC44695C" modified="2020-06-17" version="1">MGEPVGAVLGAVGLAGLFTSCVEAFGYFKATQTLDADLDILLVKLDIEKAKLLVWGNAVGILEEEWHRRITQALSTESLEKCLKSIEKLLTDSDELRRTYGVKISDSPADRAIDIVSSISMSIFKRASAKFWVRRASKRPGHTILSRTKWAIYDHRRFEKLITDLKDLIDGLQICIPLDVGTQDNTIAADIQSIEDLSQLKLVEAATEGSYRTYSEAARTAITESEMGTIADVETRPSRVGLTVEAAATSSAPNFDFVQKLTYGATIFTVLTGKCHKLDSSEPCDTAQFGSQCFMSKRISDASMLSPKLSHDVAAYNHFSTNMLHDRIKSAINIPSRLSEMDYKQQEAIQRIMAESDGQSTTQQEMLDLLVPIANAYVHCAPCICLLHTALRLSASASSTLLRFFVRPDDRLTASCCHNAGRAESLTSLLNEIDDYESDIFQYPTTHRGIRYLDRSWIERRLRQMEFEEDYDEYREDFKPIVVVLGEVEHTLPLLQNAHTPAIPKEGEIWKLSKNAEGYVRKFLFSYSRKKRSFGGSPTTNDPVGVQKRGLDQSFSRSHGRYSTPESSSSKRKKVTHELLDDQTNDESAEDDEDDEESTKGGQAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS47</accession>
    <name>A0A6A6NS47_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_99658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS47"/>
    <dbReference type="OrthoDB" id="10029320at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="49620" checksum="BF8AE0F55CA2342E" modified="2020-06-17" version="1">MDARILCTLCLQLLAGALVAFSKSSVCQLIGGTFFLSSAMHWTVVLINRYLNVSADSTYLEGNAIPVIITDNKKCKEMLGGDRTHTGAGIPGIQEKLAARARPNFRLRLAFGIDNAFTTDDEVWYREFKKRVQCSLKAISQERWHILARDARSLATSKLQRSASSPLVPLVQSITLRITLEAFFPKNPVRLRDQHIETVAGEINRVWMVSKDDPRSESWRCQLKLRDALAELIPDAKVFEPRENPLNIILPAYETMWRVVLRCFVEVWQRHVEWQGAFEDLLRNPGASQAPGEGHNEARAFHAVKEAFRLYPPTRRVHRHYADPSTAKRVWEAADIETCHRSAEVWGPDPLVFNPGRWANAHANLGASLLAFGAGDFTCPAKAGFGYRMAAILVAALLDAVGQGPWKLDMGNDEEELAEGVPMLSGRDAYVQAMLVRSEEECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSA5</accession>
    <name>A0A6A6NSA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSA5"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="290" mass="30610" checksum="FD42FCDA41677CDB" modified="2020-06-17" version="1">MSTSPTQKLSLLPSALPSSDSEKTHSRPAADRDAGSGELAACSPRLAPAYNAGDYDDDVPYPEGDSHQLLPPPNFAPFFSLIDDIASGEHYHPAVHYVFADDDPDLVTAASLQALGVDSSSRPPGAGEDEHAIAEGVAESQASLLPPPRPGVRERFLIVDLAADGQTVTEAKSLNADWQVTETVIGAAPTWDEDTVENGGAGLMLRIEGTSVADGETTTSSKMLTGARSAADGDLIAGMDGIVRRFEQGMQVLRKVTSYEADCDEPDNQGSVEGVPETIERDFEDNRANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT42</accession>
    <name>A0A6A6NT42_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT42"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="226" mass="25362" checksum="95C4C9FC7AC49F7C" modified="2020-06-17" version="1">MQKRPWAPGLCWRELRYALDWLQSPAAGASGRIVLRKSLRSTPQTEETARFALYCAVLRRRMRPPERWRNKVPFERRRHIVRGAGSRRSLSISDRARPGRESWQRATPGRTVAAGRAGGSWVERQWAQGQPVGLAVAGEAQRPGRPVRRRRRESGLRLGQARRQNTTGVGAVALPATIVMRAFAIAAWICVPRTSAPCTLASSLRPRHQPFPQSRPGRPKAALMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT55</accession>
    <name>A0A6A6NT55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Uridylate kinase</fullName>
            <shortName evidence="9">UK</shortName>
            <ecNumber evidence="9">2.7.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:UMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Deoxycytidylate kinase</fullName>
            <shortName evidence="9">CK</shortName>
            <shortName evidence="9">dCMP kinase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Uridine monophosphate kinase</fullName>
            <shortName evidence="9">UMP kinase</shortName>
            <shortName evidence="9">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_373785</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UMP + ATP = UDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Predominantly cytoplasmic.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.14" evidence="9"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT55"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009123">
        <property type="term" value="P:nucleoside monophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000315">
        <property type="entry name" value="Adenylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03172">
        <property type="entry name" value="Adenylate_kinase_UMP_CMP_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006266">
        <property type="entry name" value="UMP_CMP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01359">
        <property type="entry name" value="UMP_CMP_kin_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="9">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="9">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="109"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="23718" checksum="B0FA2450E3B9A12A" modified="2020-06-17" version="1">MPTADEILGRTKPIWTPPGVTVIFVLGGPGAGKGTQCARLVSEYGFAHLSAGDLLREEQDRPGSQFGDLIRENIKNGVIVPMEVTIALLEAAMGRVMEGEGKRKFLIDGFPRKMDQALKFEEAVCPSAFTLFFDCPEDILLERLMKRGQTSGRSDDNAESIRKRFKTFVETSMPVVDFYEKQGKVVKIEATGSPDEVYETVKERLRERGVEAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT99</accession>
    <name>A0A6A6NT99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_423479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT99"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="136" mass="14440" checksum="B9A314403BDE45C4" modified="2020-06-17" version="1">MRHKPSTSLAAAPPPPPPFARPLPLPLRAKTRRGGAGAAANRRTGSVSSFVSGTHTESASGANPVVDDSYRMVLRHQEADIETVDGSRFFGPQGHLFQLEVRERIPVFAHKLGVPSGREAEIGVESRRPPNSSGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTC4</accession>
    <name>A0A6A6NTC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_100737</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTC4"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14096">
        <property type="entry name" value="STKc_RCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000425">
        <property type="entry name" value="Putative calcium/calmodulin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="155"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="467"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="580"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="617"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="642"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="300"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="689" mass="76511" checksum="90E6344306E1DB7E" modified="2020-06-17" version="1">MFLTMIENLKNFIRHGKQARAGNSPHGEATTNVSNVHAHHQPRYNDHGAAQQQAQHAAAVSEPNVAQDHMPLQANNAAAAAAADYSVAAVDNRNVAAKAGEAAARAADDHRKARAHEAAQKDRKKDIDPSVLERIVAEERESKGKMPRYPGLDRWILIEKMGDGAFSNVYRARDSTGQYGEAAIKVVRKFEMNSSQGDNVLHPDFKKAPKAAERANILKEVQIMRQLDHPNIVKLLDFSESRQYYFIVLELCPGGELFHQIVRLTYFSESLARHVIVQVAKALEYLHEQAGVVHRDIKPENLLFYPIPFIPTRNPKPKKPEDEDKADEGEFIKGVGAGGIGQIKIADFGLSKVIWDSQTMTPCGTVGYTAPEIVKDERYSKSVDMWALGCVLYTLLCGFPPFYDESIQTLTEKVARGQYTFLSPWWDDISKSAQDLVSHLLTVDPEQRYDIHQFLNHPWIREADEPTTAAADAPPLATPAPQKEPAPKPVDPQATLQPSLYLDDMTPGSGRRLDFRSPGAVNLREVFDVGYAVHRQEEEGKRRKNFKQGYRGGAGMTSLNALDEDLDEAVEDDDDVYNESAPYDRKAQHPPAKLPKGSANNDVSAMEKQMRNTTLSAAAQARQQQQQQQQQQQKGYGQHSPAVAAAAKRQARQNRGAFELSLDNATLLERRGKKPNPSGLREQMVAGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTH7</accession>
    <name>A0A6A6NTH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Swi5-dependent recombination DNA repair protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_102108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTH7"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28527">
        <property type="entry name" value="MATING-TYPE SWITCHING PROTEIN SWI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28527:SF1">
        <property type="entry name" value="SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="38240" checksum="8BE4731DCEBD74C7" modified="2020-06-17" version="1">MSTPAAKRRRLEASANVLSRPFKSPFRSSINPPQGSSESNATTLANNASASQKETSSEKALLRAKTKSDVNPYVGSPETELGGDGKKPGAEPVLRGMTCAGTAQSPITPRAAQPSASHHPAPSSTATPTASTIALSTKIAALRTEVDMLTQAIAIVSPRGRERDAELEQLRVKWRDVSRAAAEEVFAGCKERVMRMGGVGAWREREKKKEERWKDWEEGEESDGDDSEDEEDDEDEEEEDEREDDNREGTGNCIMDAEARMWAREFKREAKEVAREQKRMLKAAKEEARREKELEQERLKVEQDALEEKDDDTFTMDMMLKTLNVDLKLIGWDRELQRWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY2</accession>
    <name>A0A6A6NTY2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipo protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY2"/>
    <dbReference type="OrthoDB" id="1901244at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="22145" checksum="C324A6741DC6C6DE" modified="2020-06-17" version="1">MLFLNGFHFISGQPDAYIHANHHCSIMNADFIQCAIYVPGTNPARLAGIEYIVSGALFSTFPHEERQLWHSHQFEVTSGYLTEPGTPEIVDHEIMKILVNSYGKTVHTWRYDQKDNDVPLGIPEFVNGYTGDGQLPQWFVDDRDELMNVNTTATRIAREDIEPPPVQEGADSWKYGYVITYGIVNTTTDTTFDGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU39</accession>
    <name>A0A6A6NU39_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein YTM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YTM1</name>
        <name evidence="12" type="ORF">BDY21DRAFT_290610</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR12/YTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="534815at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03029">
        <property type="entry name" value="WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028599">
        <property type="entry name" value="WDR12/Ytm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="11">
        <location>
            <begin position="747"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="domain" description="NLE" evidence="10">
        <location>
            <begin position="895"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1075"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="451"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1112"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2454783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1349" mass="144463" checksum="AEBC722C4091F9EF" modified="2020-06-17" version="1">MAHTPTDDELATAVLQFVDQGTFPESEAIASADVRGGTLPKVLEALSKAREDAKAMFPKQTELRTLSRTAAPTTTAWLTRARALESALATSRATASSIVASAHDSASLTAAVDDAQARVNLLESELVFNERVEASLEAVAGIAALLDEAQEDALRDELVRALENVEEAVETMERVLEGVGEEGRGMTAVAAALRERGAQLRGAIAENAVECWNALVVVDPGQRKVTVKDEIQSESTVNINPIIEALSRLNLLDTSMARFARDFESTILLPRLAFASTSPEPARTLSPTAASYSDTSISAISIRNDDIALSGPQYDLSTAACLHDLHRVAAYLSTRLPPSISAPLFENLLPTIQAHLVPTWLDATVPLSLDAIDDFQEVLDLLTGLAEYVAELGWAGKEDLLDWVEKAPKNWLARRREDAVDAVRGLCAVAVREKVVVERVEREVVRNEEVVAAATQEEEDWGAEWGDEGEGGEDLSGQAATGQGEDEDLSAWGADDDADDDSKSDERPAMAKPEQDGDDYAEDDAEEAWGWGDEDGEANKPAAPKSQAPGNGALKTNGTGAKGVQQEPREREVELRENYTITAVPDGILEIIAQVIADAEELAQPRFADTAIAPAAAGLYSIPTLVLAMFRATASPYYTPQSGANMLLYNDCTRIAEQLSTFLAEQAARDADPANPTTAHIPAAVRPSARLRLGPDLKALEAFGRRAYGREMEAQRTVVRDLLDGAQGFANSTAQPFKSECENAVQMAADRIRDVGREWEGVLSRSALLQSLGSLVGTAVGKFVNEVLDLGDISEEESKRLRELGEALAGLSDLLCVRQEEDGQEADMSGVYAPGWFRFQYLMEILESSLADIKYLWSEGELALEFAPDEVVDLIEALFAESEHRRRAIAEIRRSSLRRYPLSTLVNTLLETPRPIPFDFLIDGRPLRSTLDDYLTQHGISAETTLTLEYIRALVPPTQVTTFQHDDWVSSVDVLSASSAAGATADVRKGWERILSGSYDGLLRVWSSAGTVVATSPTVADSTLVVPAVKAARWVSATQIVSSGMDRTVRVWHYDEPSPGDLEGPPASLTPTLELYGHTASVDTVAAHADSARFLTASADGAVGYWTSDKSAAPRAPDALLPSSHKRRKLSASSKPASQRGPLAMLKAHTAPSSAAFFAPADHTVAYSAGWDHALRTWDLPTATHVDARALGSALTCGCGLAPSLGLLAAGMSTGVVACVDPRAAAGGEGGSRVAVLTLRGGKAAVPVGAVVGGERAGSEWGVVAGSWDGKCRVWDVRYVRPAAGAEEVGQGWVGMVGDSVWLFGREGPKAEEDRKVFDVAWDREIGIVSAGEDRRVQVNRAPETVGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU63</accession>
    <name>A0A6A6NU63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_373506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2454984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU63"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13889">
        <property type="entry name" value="CuRO_3_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267:SF1">
        <property type="entry name" value="BILIRUBIN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267">
        <property type="entry name" value="CUPREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025463146" evidence="4">
        <location>
            <begin position="21"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="75"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="374"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="569" mass="65048" checksum="A6DB79AEE447BBE0" modified="2020-06-17" version="1">MFTTLRFLGCTAVLFGQTYGAEWEWLSPVYEKFFEDPMPIPPLKTPKITYTNPNTSIPIDYYEVEISAFDVAVYPDLEKARFVGYDGMFPGPTFRIPRGRQSVVRFTNKDNVLGSSIHVHGSYTLAPFDGWADDMIMPGQYKDYYYPNTQSARPLWYHDHVYSLTADNAFYGQAGYWIIEDENEAAMGFPSGDYDLPLMVASHQFNEDGTVFSPLNVTDELFGDIISVNGVPWPYFKVEPRKYRLRWLNASLSRVFELFFEADGEDGQRIPFQLIASDGGLMNRPVMSPEVVMSMGERWEMIFDFEPFAGRNVTAKNPREVGTVEDYVGTDRVMRFVVGDTVTSDTNNRGAPDQMNQWSFEPPTTSSSDRLFFFARNNDVWQINGRTFGDVENRVLANIPRGSVEIWDLENGSGAHTHPVHLHLVDFIVLSRKGRRGLLPYEQEAAKDVVWLGPNEGVRVAARFAPWDGIFMFHCHDLIHEDHDMMVAFNITQIEGFNYTKSTKYIDPMDPRWLPAPVEDSIYETDNVMAKLEMFASLGVYDDIPGLQDALDQYYENRTESAIALKFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUI9</accession>
    <name>A0A6A6NUI9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_381032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUI9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="409" mass="47277" checksum="DBB1634DE074705E" modified="2020-06-17" version="1">MPPQGERIHCSRAKVRSQLKTVSASISPSKKATPDQNATHPLGTRLLTSPIIELDAELSQARDEFLQHLRSIQNSRSYGMPQSIGMNPRLSWDNDSLKHFFDNSSQVSKALLLMALEREAKSKPPPATRAVPMKRQRLSRQTLEELSKIQHLISKYDTTAENAAKFDEQPISTGAAPQWDKGHKFEDPVDKHYCYIQDSNLDYSGLIQYLPPSLFFVSRAIYSEVVDVFRATNKFRFDSTQLQFLCCDKNSDRLLNGLRRIEIEDIDRKYKKFRLFHRNCISEILNHVSKGTKVREIVLGYGFLYNHSYEVDMQNIQMWFQNGKQPSGTDKKLLEEQNILRNHLQALRTQVGMSDWFSTPNTEIFDRDARPEQLRQITTLKFDGNAFHTTLQNILKRKREKLEIPSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUM7</accession>
    <name>A0A6A6NUM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_351512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUM7"/>
    <dbReference type="OrthoDB" id="2501249at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070124">
        <property type="term" value="P:mitochondrial translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052837">
        <property type="entry name" value="Mitoribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP21, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="32839" checksum="58D095EA87AF66BF" modified="2020-06-17" version="1">MDMRRGAEALLRAQHQHLIATSPMCRSTSRPQCAHRLFLRPASIPSRRFLTTTTPSHQQHNQDRTPDSPPKDEPQRPASRSRVASLLDSVVGPESDNASFGIPRRNPRTSLDEYARFRELRQQQQQSGGQGAWPRLFDNAAAPKERGSEARPGQQEQQERSATDVGSSRTGSILDALRARDGPLGQPAASTTSSGPVRLDAEPAMNIKLGPELGKTVPVDKGRGVGLAQAFRFMEIQTAMNRIRHTVNMQKFHERPGLRRKRLKSQRWRRRFKEGFKETVRKVQKMTRQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUX5</accession>
    <name>A0A6A6NUX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_380805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUX5"/>
    <dbReference type="OrthoDB" id="331602at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75704">
        <property type="entry name" value="Mitotic arrest deficient-like 1, Mad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="475"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="364"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="630"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="477"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="765" mass="84354" checksum="EC25290F200F6C92" modified="2020-06-17" version="1">MAARNQRPTYDFLVGAPSPSPPPQQQRAHQLRDTLRQSQAARPAAGLPSPVTDLSNEDLRAQLKTLQYELDTLKQDRAVTQLQQQQDVRDAQQRAAADFERAQAAERAAQAATRKADALARELHEHQTRAANERAELERKARAAQERAREADEEAQEAREERASAERGARHRLDEAEARLARVQEALEDARAELQGRAAELGRTQGALAKKEEEADALQSELVKLRSVSGDVGGYEMVKRQLSDQVAHIRRLEHANREQAAELAALHKQHRSVELVEEEKRGLENRLRAIDGLRRELAEAQLRCQVLEDERRAWSSYLETEGARESGDDELRFESPEDLARAYIRERLETASLLDRLGAVQPELSVREQNIRALEDEKAALKSELEKLHASQGGAAAAAAGEAADARARARLERQKALAIRENEYLRAQFKAFDAEASEFHADSFDEVKSARIQELEGLIDSYRKELETVHADLSKAEQQASQRQPPAAAVSAGTKRPLEDAANGDATTSDERVGELRRKNRHLQDALAKQQKKAGVLEADLRAAQAQLASLRASSRVRVLELRSNPTADAEALKLSTVTTLRAENRALREQLLLEGGGGDDAAAAAAETKENAGAGARRKPDAVPAASLAAAQAEMAELRAELAQRDKKAQRMREVWSAKSAEFREAVASLLGWRLEFMPSGRVRATSLFYPGGDAAAGEANNIVFDGENGTMKVSGGPQSRFAREIADHIAFWVEGKKEIPCFLAAMTLDFYENKYEGQKSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV38</accession>
    <name>A0A6A6NV38_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_365356</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV38"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="284"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="501"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="739"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="754"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2455609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="768" mass="86461" checksum="194ED4369A2C28D3" modified="2020-06-17" version="1">MALKRKGILDEDRQPGTRVLRDLSSLPLAEQHRSRPIYIDPESRRVLLETFSPDASRAEQFLVMIAEPQSRVMHIHEYLLTVHSLFAAVSMGLKAHDICSGLASMSKTALPKSLVDFVEDSTRSFGKVRLVLKHTRYFIESSDPDALHQLLSDGEISECRVAGATDLEKEAAPSMSGLVIPGTKLAAGARENPDQPQRDNQLQTNEILNKLTEDDEEEEEVDQVHSFEIRQETVQIVQRRCREINLPLTEEYDFRNDDQNATLDIDIKPMIDLRPYQETALNKMFANGRGKSGIIVLPCGAGKTLVGVAASCTIKKGVIVLCTSTMSASQWRMEYLKWSNINPSDLAVFTSDNKTMFSGNTGVVISTYSMVTQSGARSYDAQKLMDFITSREWGLMVLDEVHVVPADMFKKVTYTVKAHCKLGLTATLLREDDKISHLNFIIGPKLYEANWQQLSQDGWIARVQCAEVWCQMTTEFYSEYLRAKWPNQQSLLFTMNPKKFQACQFLIDYHEKRGDKIIVFSDNVYALQRYARKLGKAYIYGGTGNQERLQILDNFQHNPDVNTIFLSKIGDTSLDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTAEMYFSSKRQAFLVDQGYAFKVITHLHGMDQLPGLAFTSPQERRELLTDVMLQSETAGDVEKIDDDLFSARSGGSLGGRRAGARGGAGVRRTAGTLADLSGGQDMAYVEFNRTRNKDLKQKGPANSFIKKLKRDAAKRKQANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVI5</accession>
    <name>A0A6A6NVI5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_66626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVI5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="20069" checksum="D6BD4BB9002AAA6E" modified="2020-06-17" version="1">MRHDVLGSGKRISCGEIGGGRSVGRGGGTRCWSWQERLALRVKAKASSSSSADARGVGGKGRTGQHGAGEASGRDACCGRAGGAGRALKRRKRAARRGRASDVVDARGGSRRKRAEADPNATASVRAAPGGREREQEAAGRRETPDADAAREQSSGAPCSLGGSSAKVQRRARGPGGSEVRGEERHDVGRTEVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVR1</accession>
    <name>A0A6A6NVR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_386761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVR1"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="40521" checksum="48AADD104FD2F2CE" modified="2020-06-17" version="1">MPDAGSRSLAEEIWNGQDGDQQPIPMWLDDAFAILIAAQCPRINLLGISTVHGNASVAHTTHNTLAILTAIGRTDIPVYAGAARPDKRKEVHAESIHGDSGLDGTTLLPAPTTHAQPGSAVAALVSALLSTPPGSAWVVTTGALTNAAHAFAACPELAAHVRGVSIMGGALGRGFSDAVMGQLGGRMQSFGNWSPFAEFNCDPEAASSILTHPILRPKTTLIPLDLTHQVIADSHVLGHIRGPPADHAASRVRALFLEILTFFSRTYAHVFGMTMGPPLHDPIAVVAALAPGTFFDAHGCHSGEAADEERWAVRVCVDGDDTGGTGEKRQPQFSGQLGRTRERLLKKGSQGVRIPRRMDVDMLWWLVDFALERAGAQMASASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVS6</accession>
    <name>A0A6A6NVS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SGS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_416126</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVS6"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="175"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="3">
        <location>
            <begin position="309"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="436" mass="46010" checksum="26F4D411F5B31D00" modified="2020-06-17" version="1">MDDAARGAAALQASDFPAAIAAYTAALKVHPKSVDYRIKRATAYQRCAPANWAAALADASAAVRLAVARGSRELTTQAQFRRGVALFGAERYADAAFVLDLVRQRDDKVQGLDIWEMKARKKLEGLEEGDPRGVRTAVEVPPEDEGAENGAEGNGNGQKVDAAAPAASEEKKPALDKIKHDWYQNNDNVYFTLLAKGVPKEQTSVDIQPGSLSISFPTAHSSTYDHTLEPLYAAVDPSGSSYRITPHKIEVVLKKATPGKWSKLQGDQAIASGPTPTTTTTATADDAVRSAVYSHAAAAAPSTSSGGPAYPSSARGGPKNWDKLAAELTAKKAGKSSAKKDAHGGGDDDDAGGGASAAAQDDLDDDDDDDDDAGGDEVNAFFKKLYAGADQDTRRAMMKSFVESNGTALSTNWDEVSKGKVETQPPDGMEARAWEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH4</accession>
    <name>A0A6A6NWH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">alpha-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glucosidase II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_68759</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="5"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH4"/>
    <dbReference type="OrthoDB" id="3237269at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025364190" description="alpha-glucosidase" evidence="14">
        <location>
            <begin position="32"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="16">
        <location>
            <begin position="99"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="15">
        <location>
            <begin position="402"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="18">
        <location>
            <begin position="741"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="17">
        <location>
            <begin position="846"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2455613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="984" mass="109778" checksum="2A7D2EC5E723B994" modified="2020-06-17" version="1">MAPAGSPVLTWGRPLLLVLSVLCNLILPSAAVKHDLFKTCSQSGFCARNRAYADAAASLSSSWASPYALDPSSLSFSDGQLRATVVKAVLGTDATANFPLTVSFLESGVARVTLDEERRRKGDIELRHGSKARKERYDEAAKWALVGGLELSKGAVMTEVDDPNGAAKVRYGPDGKFEAVVTFAPFSLEFLRDGATHVKFNERGLLNMEHWRQKKEKVEGEGEGEEGKQEMVDTPEDESTWWDESFGGNTDSKPRGPESVALDISFPGYEHVYGIPEHASSMSLKQTRGGHGNYNEPYRLYNADVFEYIMDSPMTLYGAIPFMQAHRKDSTVGLFWLNAAETWIDIVKAKTGANPLSLGVSGKTNTQTHWMSESGLLDVFVFLGPTPRDVTTKYGELTGFTQLPQEFAIAYHQCRWNYVTDQDVMAVDRKFDKHDIPYDVIWLDIEYTQEKKYFTFDPLTFPDPKKMHAQLDGHHRKLVAIIDPHIKNVGDYPIVDEMKSKGLAAMNKDGNAYEGWCWPGSSYWVDCFNPLAIEWWKGLFKYDRFIGTAPNTFIWNDMNEPSVFNGPETTMPKDNLHHGNWEHRDVHNLNGLTFVNATYEAMLYRDGKKPADMRRPFVLTRSFYAGSQRMGAMWTGDNQADWSHLAASLPMILNNGISGFPFAGADVGGFFGNPSKELLTRWYQAGAFYPFFRGHAHIDTRRREPYLVGEPYTSIITQALRLRYALLPAWYTAFHEASVTGAPVVRPMFYEHPADEASAPVDDQMYLGGTGLLVKPVTAEGQTAVDVYLPDSTPYFDYFDFTRYAGPGVVRVPAPLEKVPLLMGAGHIIPRRDRPRRSSGLMKYDPLTLVVVLDEAGGASGEVYLDDGESFDFEQGGYIHRRFALDAGTRALTSVDVAARKGAKTAAFERDMAGVKVERVVVVNAPEEWKGKTEVHVSEEGARESQRRRPVGFEWVEGAKGKASWAVVRNPKVGVGKGWKIDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWP4</accession>
    <name>A0A6A6NWP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_63026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWP4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="199" mass="21828" checksum="C3CB1A8F636197A3" modified="2020-06-17" version="1">MQTPYASAVPALALLQTYFDLPALPCREELEGHATADGRVVRRFGRSDQNGRLAGGPRGQISTRSVSGRGPPNLGFTYVQSPTSPDHNPVVYHHHTMECEVDGQDKKTQKRTRPRRAGKVSTLTAQPPRSGQSSLASKLSNRGKKLVAEKPRLCFKNGPLETHPLYLPCLSYPALQLIARRSWAAKGRNPRADKANGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWU9</accession>
    <name>A0A6A6NWU9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CCCH zinc finger and RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_348342</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May be involved in the turnover of nuclear polyadenylated (pA+) RNA.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWU9"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000647">
        <property type="entry name" value="CCCH zinc finger and RRM domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="374"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="235"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="324"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="448"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="723"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="614"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="785" mass="84641" checksum="843DB6126AB3F93C" modified="2020-06-17" version="1">MPPISGEDEPALKKWVISRLEDISDADSDVLADYVLALVVDTNGTDEANKQSAKENLVDFLHDQTSSFVDDVFGVIQTKAYLPGHVASHSQPVASQTTTAVAPAPVQASNPPAGPSALNPAAQGFVPGSGDNNSRKRAFNDRETSEPRDVKDPHYGRASAGERSMKQMRRGVGRGGGMVADRNWRQGGQARDKNFAGFPGLGSPGLPQQPNMPAQQPSFPPFDFGNPMNMMLGMQQAMGMPPMPPFSQLSSGSPTGFRPGQQPPGFPRPGQQRSPSGDMPPRKFGQRCRDYDTKGFCSRGANCPYDHGPEAEAYDPQNASLKMDIDKPLTDHPPSGHHRGRGGRGSRGGGGHGQTRGGRAPFSSTGPNFDKSNTKVVVEHIPEDKFTEEAVREYFSEFGNIQEVDMQPYKRLAILKFEDYASAKRAYNSPKAIFDNRFVKVYWYKPEDAPPANGTSKKAAEPDSSDAKMEDTAVDPEEFKKKQEEAQKAFEEKQRKIKEAAAARAELERKLKEQEEERKKLMEKLAARNARKGSSTASSPTEGAGSPNKSILEANGNTTDVKTDNLRAKLAELQAEANGMGLSHEEQQESSGEPAPWVRGRGRATYRGRGGYVPRGRGFDSSRGSYRGRGGFGRGGGRGGVMRLDNRPKKVAVPGVPTGSDKDEALRSYLFSNYEFDTVEPHPERPDTQVVTFKERYVAEMFINAAPTIAGVGKVELSWVQGAPAAAAPATKASHPSAPSAPIAPGGRDDTAMGGAGSSSAPGSGPEPPKEVEYDVAEDDDRFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX03</accession>
    <name>A0A6A6NX03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_48093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX03"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="182" mass="20490" checksum="427FBB3CEBA19191" modified="2020-06-17" version="1">MMVQLMVPQSGGPNRNSLERQRGRCRQARPPIMIWTFRSVKRQKTEFRARDSNANRERFPPDRLELGRSFRGRTTTGMDGKEIERNKGYDGGGTGHLPRKGINQLLQPSRSRSVLGDHMIPKNNIVTGKWLGRECPPQSRHWLGPVAKGGGGVCGGADGSEVDSSKEVTKRNWSERRREPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXK2</accession>
    <name>A0A6A6NXK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_51811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXK2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="20655" checksum="299FCC871E173CE2" modified="2020-06-17" version="1">MSTAKGNLTLFREWMAGGWSADAKLPPPAKRQPRQVQASVIPGRRTRRAPPQGPKDTQSAARSASQRPGYLSGSHRLPSTSFSRASVASAPLPSSFHERRLRRRAPLPVPPETLRKLRKEAVLTGWAGLLRRRCSTEQPALADGRRFALTASRYSAAALSSSRSCPARSLRVSKPSSRLSFRRFRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXZ5</accession>
    <name>A0A6A6NXZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_50342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXZ5"/>
    <dbReference type="OrthoDB" id="2537459at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025328835" description="WSC domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="496" mass="52582" checksum="EDCC593E55EB556E" modified="2020-06-17" version="1">MGPTMHLSRSALAAVASLLSLAATATALSLEYCSDFNTGQDSESMFWTWQSNGWCHDQCLGDYAFAVVQGNYCWCSDYIPANQEDTGDCDMDCPGFPDEKCGNVDEDLFGYIALPSVSPSGTMGPSPSSSEVPPSTKTSALQSATVYTFSFSSSTALVTPTSLSITYTPSTRRKRPTTSSVFTSESPVTSLRTSSLTSEQSPTAQPTSRSPSPTSSDEHGWTESRHDDGTSTELAPSPTSSKTPVTTSDPPRTTHDSTPDSTTDHEPVTTRDSTRGSTRNSTPTTDPTSSWTPTPVTSVEIITISGAAVTKTVTSTPTTPPEAATQRAERKLSGGAIAGIVIGVLGALALIALAVFFFCFYRRHRSGSDAGDDESAKQPPRRNTSVLSKVGLLSEKHSPASVAPTAIVPPVNLNNNGATSDSTDPNSPVSDKRASRPMFYDQRLNPSALMDLDNGSRSSMITMEDNRDYTRALNVRNPDPDGVSLASHQVQTPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY55</accession>
    <name>A0A6A6NY55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_51315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY55"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="246" mass="27139" checksum="F70F89899927A728" modified="2020-06-17" version="1">MYLHPFWGPVPTRNPYRPFDLQAPPPAGKFTRPPHTYYLHSPSTHSHPTYLNSPHRPTRSPGAPCARVSDRHSSPPDVLHPRPRGAAPPRRGRNCLEGFESRAGARARRMRRRAHICTVCTQPHRYVCMELGKSFGSRSLGASAARCTLRAYVRSVYVPSANVPWGRSPRDLGVGGGGLVEGEGIGGKAERDARVALDGGISRVMRREEDGVNGLQERRNWAAPLAVRSNWARDAREVSPANYVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY91</accession>
    <name>A0A6A6NY91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ABC transporter domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_348277</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY91"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000001">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040533">
        <property type="entry name" value="EF3_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047036">
        <property type="entry name" value="EF3_4HB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17947">
        <property type="entry name" value="4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="HEAT" evidence="13">
        <location>
            <begin position="192"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="449"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="695"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1002"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1038"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1069" mass="118500" checksum="B2F39DDDA6B13EDB" modified="2020-06-17" version="1">MAPGVDMAPPASSAGASKSENAKSLKVLEELVSKLSISKAQDEINSVSHDLATFINGDIEEQDAPTKIFDQLKKQLGNKKDALARERALDAIRAIAQHSNVSAAVEPYLVALLPNVLSAVGDKMSAVKVAAQTAAQAIVEASNANGVKAIIPHIARSLRTASKWAEKMTDLKCIETFCESAPAQTAFRVPDLIPIISEAMWDTKPEVKKAAYGTMEKLCALIVNKDIERFIPELIKCIAKPENVPETVHLLGATTFVTDVHEPTLAIMVPLLERGLVERETAIKRKSAVIVDNMCKLVEDPQIVAPFLPKLMPSLTKNYDTIADPEAREKTKQGLDTLVRVGDVKDGKIPEVSKAGDIDTVLGVLKQCFGPKHKEVLTGRFDPILSYISAIGGQLIDEKDTESVTWITNTLPYLTALVGEDDARTIADVLRKRASPGVEEDEEPEADEEEGEDLCNCTFNLAYGAKILLNQTHLRLKRGQRYGLLGPNGSGKTTLMRAINNEQVEGFPKQDEVKTSYIEHDLDSADTEQTVIEWTMKKLAQKNIDTAQPDVEAKLQEFGFVSEQLNSPITSLSGGWKMKLALARAVFEEPDILLLDEPTNHLDVKNVAWLEDYLINSPCTSIIISHDTKFLDDVIQHVIHFERFKLKRYRGTLSDFVKRVPSARSYYELGASEMEFKFPEPGFLEGVKTKAKAIVRVNNMSFQYPGTAKPQLSDISFQCSLGSRIAVIGPNGAGKSTLVNVLTGELIPTSGDVYQHENIRIAYIKQHAFAHIDHHLDKTPSEYIQWRFQTGEDRETMDRASKVITEEDEKAMDKIFKIDGSQRRIIGIHSRRKFKNSYEYECSFTLGENVGQKGERWTPMMTADNAWLPRTELLGSHAKMVAEVDQKEALASGQFRPLVRREIESHCANFGLDAELVSHSRMRGLSGGQRVKVVLAACSWQRPHLIVLDEPTNYLDRDSLGALSKALKAFEGGVIIITHSAEFTKDLTEEVWAVMDGKMTPSGHNWVQGQGSGPRLTEKEDTEDKVDAMGNKIETSTKKKKLTSSEARKKKKERMAKRKAGIEVFSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY93</accession>
    <name>A0A6A6NY93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_273442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY93"/>
    <dbReference type="OrthoDB" id="289721at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000034">
        <property type="entry name" value="TBC (Tre-2/Bub2/Cdc16) domain family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF15">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 12 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="332"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="589" mass="63814" checksum="91F6D14EB067E7E2" modified="2020-06-17" version="1" fragment="single">SRRQSWQPGRKTVAELEAEYDDGDEEVPDDAVIWNVPLSPRAPMDRSASHSSVESAGAGFGFGPGPAGSTATETSAATTTGTATTTNVPPPAERHNSAPAVTAASSSSSVVAPATSAASSAVPSPTASTFGAAGPELPPQQLLMKKIRNKSWTAAMSDLSPEARNLTEALEAYAEENERKHEERVQQGQGPTPPSSATSTTGMSAAAAAALEKQRVSSTSIELPPVQKSNIMIDPLPVSKEKEKHLTRTRPSWLPPKNPKEERRHLREWQRMMARSLEADRRRAERAREERQARDQRELARSRTWERAVLPDFPAVLRDRTRRETRELWWRGVPPRCRAEVWTRAIGNELELSDASYAAALGRARGVEAKLEALGDAEERRAEVKEALWFDAIARDARDTFPELKIFQADGGPLHEALKDVLMAFTMYRSDVGYVHGTHLIAALLLLNLPGPATAFVALANVMNRPLPMAFLVHDTAAMARAYACVLAHLALKRPRLHAHLTGRLGLRPDQFLEPLFRTLFCAGAGSGVGVAAPAAATSAGVDVACRIWDVVVFEGDAALVRAALGTLASLESRLYGDVDEVLGLLGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYB8</accession>
    <name>A0A6A6NYB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_42219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYB8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="534" mass="58489" checksum="B1AFC84C64EA2ED6" modified="2020-06-17" version="1">MTTTHMECTLGATHSRLNGKRKEISDGLSIFDDGPARKIRGCFHELSSEESLLAHDSVFLIDAFHGVSTAPLASKVHDSKQRRAAVAQIAKNASEFYTINEFGDHAPASTVKCRSALSALKHGALTPTGNGHASANAVNGDTWTAPSTSAESGGEIKAVGVGSTTAPAIYPVRSRLCVPPVEPSQAASSVGRQQILEDGVKYIPAGNLAFDRVRPAVHPRELDIGEVFADNGTKELNGFIRDGTDLFAIRNYSAMREKYGTLVSDDELWDFILNKYFLLPPAKMALLDSQFRRLRDGNLAFLSGSPEVSVDEGSESEDGESHGFAASMFGDFVPRSSAERGQKDTRTKSDGGDWKQSGTYRNPQLEPAPKTVRPHESRDHSSEDEDGDGDKAPTFHPDDDVLDDETETKTPIVDLLLGHDQTFHQTDADSVACQIIWALVERRSRSEFDWDTVGFDEDDNVVDLELEDDYALGSSIKSTFKLTPFNEHNVRHGIESILRPLIGHNWNAFPELKRCSFMFIYMAPVSSQLNISTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYD1</accession>
    <name>A0A6A6NYD1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_372198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYD1"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="508" mass="57174" checksum="5CB8F7BE86EA31CF" modified="2020-06-17" version="1">MAAAVISADTAAGWAVLAAVALLTFLAYRLIYRVYLHPLARFPGPPAAAVTWWWKTYVEVIRGRSFCHALEGVHAQYGDIIRIGPDELHFANPQAYLDIYNAKNRWNKEPKLYHCFNEDRSSFGFLTYREAKERKDILNKTFSPKAIEQVQGLVLEKVDALAAAFDRDVEQDTPTNMSYAFRCMTMDIITYLCFGHAVDALKVPNYRAPIIEAMDAALGSFVLFRNFEWFKSLILGIPPRISRVISPPTRGLAELQLTLLEQISELTEHPESLDHLPHKMTIYHALMDKDSYQNGTVPSAGSLYEEAQALMFAGGDTTGNTLMMCSFHLMKNPEAHAKLRMELRAAWPDIHQPSPSLRELEKLPYLNGVIKEGLRLTSGVVSGLLRIVPPEGAKIAGTFVPGGTIVSCGSTFVHYNPKLFPEPQEFRPERWIENPSLDNYQVAFSKGPRMCLGINLAWVELRYTVARIWRFYDMKADASSAKSLPFRDTFLPSYEGAPVMARMEKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYQ5</accession>
    <name>A0A6A6NYQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">DNA repair and recombination protein RAD5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_43506</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYQ5"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF11">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G06590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="308"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="648"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="716"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="884" mass="99488" checksum="A7B4FC2D582BEE0C" modified="2020-06-17" version="1">MARTPGKRGRGVQVIDLTNDDADARSSKTPKVSSGQTACRPILSDEDDEYSDDVLDSQDALATSTDQDLYMHYGTWHTSIVGCRFYNGLCVRGEMVLVRRDPNNRYDTNAIRVLNASQVQIGHVPKLVAAKLSPFMDRRELFVEGLITGQKGYYDCPLDLQLYGTADPIRRAAIFTRMQEHQIPLTSEPSSFHSSGLPSLSQGQVEVSSAAMDATPQELQYNRTNPGATIEQFGTKEADLEKLPMAEQPDGLAVPLLPYQLQGLKWMLDKELPKLPRAGSQDVVQMWRRSQEHRDSLTNVATNYTLKASEVELASGGILADDMGLGKTIQVISLMLAGRALPNSRASDASDATLILAPLSVMSNWSLQMGRHVQKGYEMRVLTYHGTRKEPISPKTIGNYDCVVTTYETVMSEFWSREPKLKRKHGLYSVKWRRVVVDEGHTIRNANSKKAVAATQLQAQSRWALTGTPIINSLKDLYSLVKFLRLSGGLDRFELFNSSIIRPVNQGAHLGKMILQTLMQSICLRRTKDMPFVDLRLPKMTEYVHRIEFLPHEWKRYSLLEAEAKGKLETYRQQMSEGGRTAFKAYSHVLEVLLRLRQTCNHWKLCGEKRVAQLMEMIEKESVVDLTPENIEALQKMLQVSIDSQDDCPICLDTLKSPIITCCAHVFCFMCIERVIENQKRCPLCRADLPSFDKLVRPMKEQEQQPEIDIDTGSSKIEALLKILEHSREKDGTKTIVFSQWTSFLDIVQGHLGDCGFNFTRIDGRMSAIQRDRALDLLENDPTCTIMLASLNVCSVGLNLVAANQVILCDSWWAPAIEDQAVDRVHRLGQKKPTTVFRLVMEHSIENRVLAIQEEKRNLVSQAFSEKNKRGSGARVADIARILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYX3</accession>
    <name>A0A6A6NYX3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidyl-prolyl cis-trans isomerase-like 2</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cyclophilin-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Cyclophilin-like protein Cyp-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">RING-type E3 ubiquitin transferase isomerase-like 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_372382</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYX3"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01923">
        <property type="entry name" value="cyclophilin_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 20" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="19">
        <location>
            <begin position="39"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="18">
        <location>
            <begin position="311"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="488"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="544"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2456945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="585" mass="64668" checksum="E78DCF91DEA73721" modified="2020-06-17" version="1">MGKGTDKLYITHSEWASSDAYSASAGAGVGARRDAPTFKRLPFNYCALTLQPFSHPVCTPTGTVFDLEHIAAYLKKHGNVNPVDGGPLKPSELLKLDFTKNEDGEYVDPVTMKPFTDNTHLVALSTSGNVFAWDTVHRLNIKAKNWRDLVSDEEFSRKDIITLQDPQNVVDRDISSFKHWKESDGAEPEGKGSINTAALGSGADLRVLKAKEAVAKSREERAKTNDPNHTLSLQKKAGAQGTGDKPVNVGMRPARAIPANASQHTTGMAAASFTSTGVTPHTSGERALLTDEEYMLRPKRVKMKGYARLVTNLGEVTIELMPEWAPKAVWNFVQLAKKGYYDGISFHRNIKNFMIQGGDPTGSGRGGQSIWNKHFNDEIEGPNTHSARGIVSMANKGKNTNGSQFFITYRALPHLNRKHTIFARAVLSAADPAIGAGVDPAAAARGAETLRRLEAVPTDAKDRPEEECVLSRVLVFVDPFEEFLREKAEGERREKEREEVRRQGGADDERTTWTGKRIRLDGKAEEKEEKEVGWYLKKVLAEKKAKEARGLEEEDEIVGEWDEPVEEPKKKKARTGGGFGNFDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0L7</accession>
    <name>A0A6A6P0L7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_343606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0L7"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059122">
        <property type="entry name" value="Beta-prop_WDR5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25175">
        <property type="entry name" value="Beta-prop_WDR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR5-like beta-propeller" evidence="5">
        <location>
            <begin position="100"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="142"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="390"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="433"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="472" mass="51312" checksum="F4B8C7AE749CCD1A" modified="2020-06-17" version="1">MSLLSPERMRSADGDGYARSPGSYREMEAEPQRDSYNYVASSENHAVRGGDTPDGETNLYGQGSHSYDSPEEPNGSGDYAPPSLLPQRPSKLYFKPALILRGHKRGVAAVKFSPDGKLIASCSADCTIKVWDAQTGKHQHTLQAHLAGISTIAWSPDSKMLASGSDDKSIRLWDVASGRAHRTPLVGHHNYVYSVAFSPKGNMIVSGSYDEAVYIWDVRSARVMRTLPAHADPVSGVDFVRDGTLIASCSHDGLIRIWDTATGQCLRTLVHEDNAPVVGVRFSPNGKYVLAWTLDSCLRLWNYIEGRAIKTYQGHKNLKYSLGGCFGIYGPGRTHPLPPPLQLPRYDDDDSEYNGHAGQRQDQAAQPIAYAFIASGSEDGAILLWDPNKVKGHEGAVLGVDAHPTESVLVTAGMDGTVRVWRHDGAAAAREAEEAAKEEQRRAAREVALLEAPTPTPTTADVRMTDYETAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P172</accession>
    <name>A0A6A6P172_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL13m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_385507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P172"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000007">
        <property type="entry name" value="50S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00068950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="19504" checksum="E1021FB9D84DA797" modified="2020-06-17" version="1">MSQTVGKTRLAYSRAWHLVDLSTDPRPLGRVACSIALVLMGKHKPIWDPSTDCGDYVVATGCRDLKTTGRKMHRKMYYSHSTRPGSLKEMSMLRLMEKWGGGEILRRAVSGMLPKNRLRKPRLARLKVFEGAAHPYKGNLIKIGLQEKPSKSMPKIGEMPEVKAQFQQQRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P177</accession>
    <name>A0A6A6P177_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P177"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="133" mass="14651" checksum="424896CAC59F4841" modified="2020-06-17" version="1">MGSKHASPPQEASSRPDSLPAAAISIPLSRALPKTSHPSLHALRTSLYVPRRAHARVSAPTRQAVPGRLLRSSPPLRRERFEARPMCVHTTSLAYAAQPRLRPSSRGRRLVRPLQTRPLARLHTRPALWSAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1A9</accession>
    <name>A0A6A6P1A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calcium-activated chloride channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_414780</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1A9"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="607"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="14"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="172"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="739" mass="83912" checksum="56DD37A2EE28A5F4" modified="2020-06-17" version="1">MAPPKSPGLQTNMDVDYVICYRFTSADRSEATAQFEKLTKALQSVGLDTEVRNGASQSLLVFVKVASQEHLYGEVFRSRVKDWIHGVRAAAPKKETKEALESDPLNEAERLRIIYQLITNSPTEGGAGITPKEGEWKNVESIFALHDHAYNKEWIKKWSTAYFLKAEDLDAIRDRLGEKIGFYFAFTQSYFAFLVFPAVFGFSAWTLLGQFSPVYAIVISLWCIIFTEYWKHQEYDLAVRWGVRGVSSIETKRKGFQHEKEITDPVTGETVKYYPAKKRLMRQLLQIPFALVATIVLGTLIATCFGIEIFIREIYNGPLQFVLVFLPTGILTTCLPILTAILTNFASQLNSYENYETDSSYETAFTQKIFVLNFITSYLAIFLTAFVYVPFGSWIIPYLDIFSVTVKPFAENEQQLKAPEEGFTINPDRLRKQVIYFTVTAQLVNLGMEVVVPYLKRRGFAKFKKMQSDRAAKNGGGTADVAANDPPEEAAFLARVRNEAELDVYDVTTDLREMVLQFGYLALFSVVWPLTGVSFLINDWVELRADAIKICVEMQRPTPWRADTIGPWLDSLSFLAWLGSITTSALVYMFSHDGVGHVGTPADIKAWALLLCVFLSEHAFLLVRWAVRIAIGKLDSPGRQKERRERFLVRRKYFEESLAALEHAPKQYGEENVALATGEDGVKISRESLEEEARRQSEHGMSLEERFWGRQKGWRECAEVGKRLIERASTEAGEGKKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1G5</accession>
    <name>A0A6A6P1G5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ssDNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_345533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1G5"/>
    <dbReference type="OrthoDB" id="1078367at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="148" mass="16244" checksum="E94BE5578A5D60E2" modified="2020-06-17" version="1">MAASFSPLRAFRPVASAATSATRSFSSTTRASFARMTVIGRLAAEPELTETSTGRQIVRYALGTSFGSGENKKTSWFRVTNFDEPGARRDFLLSLPKGTLMCVEADANMHTFEDNQGEKRTILQLTQRTMEALSRPRPVVESSEEATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1M5</accession>
    <name>A0A6A6P1M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Signal peptidase complex catalytic subunit SEC11</fullName>
            <ecNumber evidence="4 15">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_320258</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3. The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids. SPC associates with the translocon complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase S26B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="4 15"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1M5"/>
    <dbReference type="OrthoDB" id="10257561at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009003">
        <property type="term" value="F:signal peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00728">
        <property type="entry name" value="SIGNALPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="170" mass="18884" checksum="D443040C38CE5637" modified="2020-06-17" version="1">MFGLQPRQLAAQVLNFALVLSTAFMLWKGLSVATDSPSPIVVVLSGSMEPAFQRGDLLFLWNRGMDTQIGEVVVYNVRGKDIPIVHRVVRRFGGGVKPLQLLTKGDNNAADDTELYARGQDFLDRQRDVIGSVKAYIPFVGYVTILLSEYPWLKTVMLGLMGLTVVLQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1N1</accession>
    <name>A0A6A6P1N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1N1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="61" mass="6567" checksum="0F59D8D490D5D2D9" modified="2020-06-17" version="1">MHASRIACQRTSNMEYGAYSGQGARAFLVCGEHANIRHAAQPATPVGRLPTAACSTHREQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1T6</accession>
    <name>A0A6A6P1T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_285235</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1T6"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="328"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="615" mass="68529" checksum="F2B7CC689011F7EC" modified="2020-06-17" version="1">MPISSPILSLRSETDFNDIEPNLDSTDPFRFSHGLTGVDQIGNYFYDKILIYMFVGLAFFTVVVCIGEQIGAFLRRISTVDTHQSQRIWSMNLFPVWSMVKKHLVYAPLWKHRHNRELQLSKAVGLGTLPSRLHIILIISYVLANIGFCLAIPWDGSRSSVTAALRGRSGHLATLNLIPTILFALRNNPMIWLLRVSYDTFNLLHRWVARIVIFESIMHVACWLANTYNAGSWDGVGDAIAGAVSYRWGLVGSIVFVFVGLQAWSPLRHAFYDTFLNIHRISALTAVVAVYMHLNLHTLPQQPFIYTVFALWGFEYVLRAISVVYYNIRYRQLTTITVEALPGETSRVTISLVRPWTPRPGAHLHIYVPRVSYLISHPFSVAWYGTRLSSPSAESLPMTHQDIHLSDNNTATNTLSLLVARRTGFTRRIYDLAAAQPSGIYKATALIESPYGGQVRFDSYGTVLLFAGGVGITAYLTHARALVQGSLSGTASARKVVFAWAVRDLAALEWAADWLEEICQLGGGMGASILKVRIFASARQRTARGGGDGETATEQQLSNRRCNVGEVMDYVFHDRDGAMVVGVCGPGPLSDEVRACARKKVTLGWVDFEEEAFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K5</accession>
    <name>A0A6A6P2K5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_20037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2K5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12517" checksum="C64BB1A78591085F" modified="2020-06-17" version="1">MFMSCTTSSAGSPADPTQRHHPPRSRHAVAHLHLPMPYFASPRTGFRCLACHMAPNDPFTSRCRRPSAPKEPLRHEPTSTRPFKRLPSYPRRWPSRLLMNLPESGPGQMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2X3</accession>
    <name>A0A6A6P2X3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_414643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2X3"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF12">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32647" checksum="18D42BF602C92123" modified="2020-06-17" version="1">MSPWTLVSPASRGIGRALARRLLQTTDVPVVATARRDLDKSREEILSGLEQVDERRLKVLRLDVLGACVWNQDTHCLIHESTISSAASECGKLFPPPAHHLRLTFAIPGLLFPERSPAQIDAANALLTFRTNSLGPLLLMKHFEAFLPSKKQLKQQERRRGGDPGAADLVVGADGGASLAPARNLPPHAVFAAMSARVGSVSDNALGGWFSYRASKAAVTQAARSFDVHLQRSAGRAAVALALHPGTVKTELSEEFWGSVPKDGLLEPEFAAERLCEVVTREVGVDGRGRFWDWKGEEILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Y0</accession>
    <name>A0A6A6P2Y0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Y0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7041" checksum="65BCBC27CB94B79F" modified="2020-06-17" version="1">MAHAYGAPSYISTQGRRQDQQLFVADCGILRHPASLFCGACPSIIGECVWGAARGPHAGVIASTIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3H0</accession>
    <name>A0A6A6P3H0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3H0"/>
    <dbReference type="OrthoDB" id="5231661at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="14921" checksum="26F6D3B89D1F8DF2" modified="2020-06-17" version="1">MLRTKVAATTKTLHPTPTRLVSPRHDQAPPSSLHHPCPAPAPQQQRPLSTSKEPPRKPNPDAKSSPSESDPETPSFSFKDLGATKTTRVVVYGALMVVGTAETVTWGTWAWRKFGPKNEDGKDEEGEGGDERPAQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3X9</accession>
    <name>A0A6A6P3X9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_420576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3X9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="166" mass="19087" checksum="4BABAA0B647B8E40" modified="2020-06-17" version="1">MGKTLERMLDYVLNQSDLNWSTVILPQAYRALDRCREVIDLLQHRVAALLDSKAEAEFVTSDFRILLCEALFDSIFPATARFYHSLGNWQEALKTWNYVLGYGHVDQEATPSGSYDRQYDVVVSVYSLGVAYVRTGDKEKTRQIVEITESEPKRLKGRNKESDYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P415</accession>
    <name>A0A6A6P415_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adaptor complexes medium subunit family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_362792</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P415"/>
    <dbReference type="OrthoDB" id="870at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd14837">
        <property type="entry name" value="AP3_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="5">
        <location>
            <begin position="182"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="348"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="522"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="615" mass="64207" checksum="C26DBA62CE9B288A" modified="2020-06-17" version="1">MTDIEALYIFDAHNNCILEHVYASRPPPARTVLPLYLAHPSPRPSLLHLPNTTPPVLLYSLVQDQLLFLSPHTSDTEPLLVLEFLHRVADALEDFLGSPLLASRIESRYDVVAQLLGEMCDGGLVASTEPNALRDLVSTESWVGKVMGGLGLPGASSFKHPVGPPPSLPPVPWRRANVRHTSNELYVDIVETLLVTLSPSGLPLRATANGTIAFTAKVSGVPDLLLSLTCAGGGKQAVEKTVRLPVFHPCVRLARWRERPGTLSFVPPDGRFVLAGYEVDLLAGRGLGGDVDIPTPNAVGSKGGSSGAAASAAKLNIPAAVEVQTGLGPSGSEFEVSLFLSPRSMSSSASSSSSSLGGASTPSGSGGSGGGRPGLNRGLSSSGSNPLAALSSFSSAGTSQAPTLSDILVRIPLPPSVKSLPEIRPSRGEAMFAAADMAVEWRIASREVTGLMGAGRSGGGRGAAPAATLRCAVVGMVSDDEDEEGEEEDGDAVGGGVAQWTGGRVAETWEYDDPSAMAVSYQNEPALTGQNKKRARKDAVEKERERDERRAKQNAVLMPSGAIVSFQVKGWLASGVRVESLNVDTRASRGLGAGVTPFKGVKYLTVSDEGVESRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4F1</accession>
    <name>A0A6A6P4F1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_283724</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4F1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="14"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="132" mass="13944" checksum="A5A2805A11B8257A" modified="2020-06-17" version="1" fragment="single">HRRALEVPTDLPDDWEYVSCWTDSVGARTLNGATYASGDAMTASSCASFCGSRGFKYAGTEYAAECWCGNALAADSDAAPSEADCDMACSGDATQPCGGSNRLTLFENAGMEDVETVRSEGVGRWSYIGCYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4T9</accession>
    <name>A0A6A6P4T9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis ATPase RIX7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_370505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4T9"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000081">
        <property type="entry name" value="AAA family ATPase/60S ribosome export protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000018">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000365">
        <property type="entry name" value="Ribosome biogenesis ATPase RIX7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="203"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="515"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="402"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="740" mass="81782" checksum="3909BBC8C4E6C2E5" modified="2020-06-17" version="1">MPPTSGRGRVTLQQGLDRQVHQVTRSLLERNSMEASQASAYAVYDWIKTSNSSLKRRPQRQLQDSIERALAVIQQDEQSDGGDEGDSMNALEGDFGDREREEREALSANAMNRAIVGGWTSAGTSTPMADRKESKKREGQRQANGEPMKKKRRPATEEVDRSPPSHVRLEDIGGVDNIKRELKEHLVLQLLCPEEYVKRRIPIPRGILLHGPPGCGKTVISRAFAAELGVPFIEILGPSVVSGMSGESEKQIREHFEEARKLAPCLIFIDEIDVIAPKRDSAQSQMEKRIVAQLLISMDSIAMEANDNKPVIVLAATNRPDALDPALRRGGRFDTEISMGVPNESMRELILRAQTRETPIANDVDFARLAKMTPGFVGADLRDLVGKAGTWSMDRYREALEKQAAEGEEEMDIDGPADRRNQSEQDRSIGRLIKRVTQKDRARPLGFEDTTITMEAFLAVLPSIQPSSKREGFATVPDTTWADIGALTTVREELQTAIVEPIKNPQRYAKVGISAPTGVLLWGPPGCGKTLLAKAVANESKANFISVKGPELLNKQAQFVGESERAVRQVFMRARSSVPCVIFFDELDALVPRRDDTLSEASARVVNTLLTELDGLAARAGIYVIAATNRPDIIDTAMLRPGRLETLLYVGLPGADERVEILRALIRKTPIDVAFAEVGRGCDKFSGADLGSLLRKAGQLALKRGAEEVREEDFAKAMEEVKPSVGDLKRYQRLREERWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4X2</accession>
    <name>A0A6A6P4X2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4X2"/>
    <dbReference type="OrthoDB" id="4140189at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="227" mass="23548" checksum="63B41ADEDB1DC591" modified="2020-06-17" version="1">MTAPVSASELAKLFTDQFTEKLSSPGLADLFSSHLSTKLAGTTLDNSTLKLHVELLAYQYAIKLASEFPAKLVPNKNNAEVKTKDSTSRSSKVSNSTTNPQTPPAPKAEAVSTRTSSTMGINSKVSDGSMNDGVGGPVRSPSQASTSSAQPTYPNAAPTPGMSSSTNPVATNHSSATSQGPYDRPSSGIGSYQSGSDNSVKTANGSSSAPSVYDKAARADIRRSRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P561</accession>
    <name>A0A6A6P561_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_339906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P561"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6417" checksum="16E4F47513603F67" modified="2020-06-17" version="1" fragment="single">MLIVTKPFAAIPETKRTRNQSARSTLGSAYVMALSSHLLPTCSLRTRCAQVLFGSYSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5C1</accession>
    <name>A0A6A6P5C1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_340849</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5C1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="77" mass="8442" checksum="5C6D00C0B625E083" modified="2020-06-17" version="1" fragment="single">RLLKRKEPLRVSNGHQMLDDEALDAQLQREIAEDAAIVVGGAKKRRRCKKCGTLGHNSRTCQTNTAGTGDQSEPQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5H6</accession>
    <name>A0A6A6P5H6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transaldolase</fullName>
            <ecNumber evidence="2">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_340241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5H6"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="321" mass="34597" checksum="F2F5019066B2AABC" modified="2020-06-17" version="1">MAKQSALQSILASGTVVAVDTADFNTLRKFGASEGTTNPSLLYAAAADPQYARLVDEAVAYGRSIAAKKERRQQAAAAVEYLAVGFGTEILDCGCKCVATEIDVRHSFDTEQTIAAALRVIALYAQRGIAADRVRIKISATWEGIQAARKLESEHGVGTLVTIVFGMTQAIAAAQAGVTMIAPYVGRIGDWHKARGSKEGEMMGVVVVSQMQAYLRKWSFKTKVMGASFRSPEQALALRGTDVLTIGPKILDQLAEMQVENAPEPVTLPDGALEEQDIGKSEDAFKWAYIHDACAVEKSAEAMRKFGEDTEMLEALLLTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5I7</accession>
    <name>A0A6A6P5I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_282910</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5I7"/>
    <dbReference type="OrthoDB" id="431825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="188"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="666"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="408"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="701"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="565"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="614"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="641"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="701"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="741"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="755" mass="84815" checksum="F632A3EE081E5426" modified="2020-06-17" version="1">MPPKQKAPKGRASNSKTSNIISDPRFANIHTDPRFRLPSRKQTRVKLDKRFARMLEDEDFSRKATIDRYGRKIGKEQGRKELERLYRVGDEDEDEEAKEEKVGRDEAEEESDEPDDDDVVQRELRRVDRAYDPAREGGFSTSEDEASSSEEDGEDESEAATEDADMVTLAAPGPAPREADVPLGDVSARLAAVNLDWDNIGAVDLLAVAQSFAPPDGAVLSVAVYPSDFGRERLEREEVEGPPREIFGQDKGEKNDRNGAGSESEDEDDGADEQDVQGAEDYSSTALRAYQLSRLRYYYAVITCSSASCAKALYDAMDGREYLSSANFFDLRFVPDSVSLKEDTPRDVCEKGQVPEGYRPNEFITDALQHSSVKLTWDADDMRRKEVQKRAFKAARGEEVEEDLRAYLGSSDSGDDEKDHGVQNSGHGRTEKNAPPDGKKQAKASALRAMLGLSADPQPQSKRKGEKDIGDMQITFSSALANYDGDKKKSVFENEPEETTIQKYVRKERERKARRRERARARRPGLDAGKEFRKHDALTEPDGPGSDADPFDDPFFTDPVGASRAAEKAARKAEQARRRDEEAAHKKKRETERKELELLMGEDVDASGTGVEEGAARHFDMREVMKAEKERRRRGKKGKKGGKEGQQHEDKKEGEKRDGFKINVKDPRFARLYDSHEFAIDPTNPRFRETEAMRELLEEGRRKRKVVEEREGVDKMDGRGEEKSKKAKVGERTGTTAADGDNLKRLVEKVKGGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5I9</accession>
    <name>A0A6A6P5I9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_341076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5I9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="74" mass="8509" checksum="BCF5821E57FAAEAB" modified="2020-06-17" version="1">MRGDAKGELREIKASQGSRSNQPGTDRARLRFLVWARQKDFGDRNGWRRNEGRQLNRDRERPGNLESRGKGSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Z4</accession>
    <name>A0A6A6P5Z4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar membrane-associated protein IML1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Vacuolar membrane-associated protein iml1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_339925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IML1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="39497at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04449">
        <property type="entry name" value="DEP_DEPDC5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045838">
        <property type="entry name" value="DEPDC5_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027244">
        <property type="entry name" value="IML1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048255">
        <property type="entry name" value="IML1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179">
        <property type="entry name" value="DEP DOMAIN CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179:SF8">
        <property type="entry name" value="GATOR COMPLEX PROTEIN DEPDC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19418">
        <property type="entry name" value="DEPDC5_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12257">
        <property type="entry name" value="IML1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEP" evidence="6">
        <location>
            <begin position="1405"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="494"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="760"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="884"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="921"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1487"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1737"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1829"/>
            <end position="1896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="765"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="793"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="818"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="847"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="923"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="948"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="973"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1514"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1745"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1833"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1884"/>
            <end position="1896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1896" mass="211800" checksum="AC870832880E9A3A" modified="2020-06-17" version="1">MAPVGLLGGALRLQKICTLGVHDENYSKDDVLFNAEKFQELGIPIGSLAQVVPLKSGIAVRDFQSPVRGSSTDKSKNESNKDSQAKSSKTVQNDKLSEPAIIFDEKGSRVQNSNRDVDDEKSYIFVTKELSPEIRQRHPMLQVSFAKPIADAFGFRPGTQAILCAASEDLHAASHVELSFRDEYLARADMWRMARGELIYKTVYRGQKLLFMGSIKAAVKSVYINGRAVHSAYFSSTTKPIFRSESARYVLFIQMSKEMWEFDSDGSGETMFSKVINGFLPELFKRWMSIHAHHLVTIVLFTRIEYEGETKPPEGSLPELGQAAKTDDNPRPTFRDFYRVVVNEMASGDWVSILYQLKKEFKVFLRDVSLIPIPPSPANGIVIPDQAELSKDQRFVIAGSPSSAARGNILEAINLAASQFATDYIDRDLVRTGISVIVITPGTGSFEVEYNMLKMTTDNLIGSGIGIDLVCLSRMPLHSVPLFKYRNPRLVTDESRVEDRGGESTPRQRAADFGGRLNLPSKVSPPSFSGHSIVSPSERPIRSASPTIPGQNSFSSNMATSRSHHPGTADEEWSFAMPHWIDISFWSGPADVNVISPHQKSLRRMSSAPFDAQNTSFAPRCRMYELQMMGVMEYDMSNVSIPFLHENPLYSHTLAEHPAWRPHSRHAHFAASSSPSMITSGRSGQRVELSSTPESDGLKETSSELGALHTYRDTLRTWMEDYDEYVFLPLHEKQHMEESHKKARRVESAQIRRVMSMAHDPGLLGTSTNSDTPYLSRSVDSHPGSHFSQSWRSRTDGFAERFESRTEKVQARDFGRSSYATTPSNSRPPTQRRNKPLDSQVSRKESIASIASKPESSSTKSSFRPPKLMSLGIAGFEAPKDTASTQLSSNIAQHHPSDRDLGSASTASSRRGILDHVRASLSRKASYSSALTDSTEVADDQGSTSDTPSKPISIRSPSRAGQGAFPTIEEADPEKPPTRPVQDVHKAAHEGAPRRMHAHRSSTEEEPGPVLFSASKGLAARVGPRRDFASTDTREPPKTLSPTNALSPWLVIVNPSNPKKNEISVTSQFRRWQHVFPRPLRTSSIKWKSLCSPASVPLTHEYFPTADQLATEYNENPYTLDLNDDTDMSEAPPDRTALMRELVAFRLSQGFQFVIGKAVAEFAGRPPSEMGDVFNPNYMIQDGSMVFMSVGNTIHQLVCVGGGQVEVKRFSRKPTAALVSPAGVDTPLVYKPYIRTVLAKDYEPREVIFRPIKEEYNWTFIDQFLAGFHDQFQYSDYLRFWRARFVLIPVDIPSTAPGRSRPIVIEGDTPEEIRLEGIRKLTQAWQKHRYIPPEERQFQARRKKLDTNPLAIEFQTRDPSVIVAAGPESSSLADGEPPLQTALWDKEPYHTSKIDLKKLAQDLQGEKGIKMTDRRWHWRLHYNCFLGVDLTTWILQSFSDIETREEAVELGNQLMNKGLFQHVQKKHMFRDGNFFFQIASEYRAPRPESKSAGWLGTRRSDKSVPSTPLTGVYSDSGRSRSGSSSSSEAGARTPTGEKPERRKVKLSLLIRYDVDPRKRSYRPEIINLHYDRLHNPDNCYHIRIDWMNVTAKLIEDAIVSWSKDVEKYGLKLVEVPIAEASGIVEEHPFRAPYLIKLALPPPDSQPQQYFDSTSFSPRAPKDKHVYHKALLRKLNFVLDMESASSFPPNVEVMYSWGKPDYKYTQYIHRSGVLLAQITDEGDFLLLANRLYARVSPRSSPHVRASQVSTLSDTPTSRPVSLNTKRDEDNVAAGAKDSNFTSHKPPTPTPEQIKEEVEAFCHDKDALRQFYADAFRPRVSPSPHITPVLDSAIPSLGLPPTLGTATTGRESSPGPPSQGHGLPAPQLQPISLQDPGRGSYLGRNRSGSQGAKSPESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P670</accession>
    <name>A0A6A6P670_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoaB/Mog domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_340199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P670"/>
    <dbReference type="OrthoDB" id="448496at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047884">
        <property type="term" value="F:FAD diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042726">
        <property type="term" value="P:flavin-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056596">
        <property type="entry name" value="FLAD1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675:SF1">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24102">
        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="2">
        <location>
            <begin position="48"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="35820" checksum="0729A26E7A85BB75" modified="2020-06-17" version="1">MYARLSQLVRQLPRPSTTAALSASRARPTSPTPRPAAMSSARTIHTAGCIVIGDEVLGGKTVDTNSAYFAKYCFSLGIALKRIEVIPDDEEDIVEATRRMSANYDFVVTSGGIGPTHDDITYQSIAKAFDLPLTLHQEAFERMKRLSKPHPSQPNFDWNVPSPALTAKRRMVEVPLDKSRDLSEQVLFLDESLWVPVVVANGNVHILPGIPRLFEKLLDCLKPRLLPRLTDPEGKGIHRILFATPMAESAVAGYLTELAAKVEPKGVKVGSYPRWHKKHNSVTLVGRDQELLESLVPEVEAAIQGHRVTLEDERDGENESDQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6L0</accession>
    <name>A0A6A6P6L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_338736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6L0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025484034" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="28669" checksum="6C8778B9CCB6CFCB" modified="2020-06-17" version="1">MRAGGEFGLAVCFLFPHVCLSTTATATAKFGDFCFEASNNAREGLAPDNHLPPYCILRVCSSINQPCLSYGALGRRASFCICLDSSSSVVGSAPLIPFIPGTCVFQANQSASLDRGPLSRCRLPPMPSTRPPFTISFSFYFGTVSRMPNQDPFLPSEFWQSGKVKRMRRNGNWWKIGFHTRHPFPYSPSRLQSIPELPPFYLSYPAVPSEQSSRSCHEATPRERGQGRPRRRASVPSSPSPFFSYSTPFPPNCLYTYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P763</accession>
    <name>A0A6A6P763_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_317810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P763"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21223">
        <property type="entry name" value="CH_ASPM_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="400"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1155" mass="125128" checksum="3BAEF1B6CE8ADDDC" modified="2020-06-17" version="1">MYRYAEQTPCPPPAPVTGNPPYYPPGTYGYPPPTMYPYTYSANDDTANVEYTTQLDVQRRMAKPRRPAMGRPKKQSFDPADILLDMPSPQRTKQGQDRAKQAPASPRASVAAQPRRRRVSVLLAEREAATRRDGAVAGEGEGAAERAIDQEQSQERQQGRLVGGPARQQGRDAEALRGPELRKNPRRRTIYVPSEDTTIFTIHPGAPSHHHRQSLGGQARRPSPDLGFDLMTVSEEGTPPKPAAAAAATSGRKSLAAAPKRANALRPAHRNHPGLNGTYKDRPGSGPGKENRPACWETGHAKRTGSNTFQFDVGDVDNLDRRELDQENVPNKAKASSRVNIFDEDAPPSWGARGGNAKHVAIAKHADDSRKRAPPVSLAVSESPAKLAKVSERRVKALNGSGSSPGSPFANTGSPPSALRRTRRSAVAANASSSAVNRVPLLARAASERASDNQPYKVLTEDLNCPELYEENWLSNQEVALTQLLNKLFESVEPVPTFTCDDRTGLRKAFLAIYHEPAFPLLFKRLQASLLYGALAIPKDLLAKAARLKDDVGLRRKFLALWLETYDLPALRAAAEAVVGREVPPPPARLSGSGAAVNSPDVQSRLRRAEKKSIEGFLDCFLVKHEDAHRLKGGAGSGAGSIGSIARARDFGGAEADDFGGQGWAWRRTVLRSLMLIQLLDKAKARGVVSGCLFQATSAHKSSAGVVGALAAMVLPSLGDVLRPLGHLNFAVSAVQYPLEELRYTVANLATDLRNGVLLARLVEILLYTPRTLRALADESDDATLTINMPTGEVLTSALDKMTGGEKKSDFDAADSWVLSQHLRYPAPSRAQKLFNVQVALSALTGLNDAARNVAARVRAEDIVDGHREKTLALLWALVAEFGLDHLVDFKEVKKEIRFLKQKLSDEGEGEESFSEDSEYFVDCDDMANGADKHQGLLLNWATWVGRLHGLTVNNMTTSFASGCVYAAIADEYAAVFPSASKEVTGSNNLTTKLRSLGCSTTFIELIAPAAAAAAVNKGPSSSHSRIPTAPFTTMALGFLAARLLPLARAHRAATRIQRQFRAHALRAAFGRRVQLMRVAAHCAAVVRTRETVVRAAVTIQTAWRKALERRIEGLVRDVSGVQAMVRGFLVREKVAGRVTGAVGRRGKMRVRGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7E7</accession>
    <name>A0A6A6P7E7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_336521</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PCNA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7E7"/>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000008">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="10">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="28586" checksum="37FEFB7358A3AABC" modified="2020-06-17" version="1">MLEARLEQANLLKKVVDSITNLVQDCNFDCNDSGIALQAMDNSHVALVAMMLRSDAFSPFRCDRNIALGINLTSLTKVLRCAQNEDILTLKAEDAPDVVNLVFESAESDRLSEYDIKLMDIDQEHLGIPDTEYAASITMPSAEFQRITRDLLALSESVSIECTKEGVKFSCQGDIGSGSVTLRSHTNVDNEDRNVSIDLSEPVSLMFSLKYLSNFCKASGLSSRVKLSLSNEVPLLVEYALPSNSFLRFYLAPKIGDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Y1</accession>
    <name>A0A6A6P7Y1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_281094</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Y1"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000002">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="505" mass="59776" checksum="BF312308A84FBB07" modified="2020-06-17" version="1">METPVIANLFRPHISRNACQWLHHRPFPCCGIRGMRPVPLQRRAAATGSRYKTRTNDETKDAETSAWKQRMNILSQSKQDECMRYPLITADELRTQRERPKGVRMLLRDFIEDSLYNPFYGYFSKQVVIFSPGEPFHFNTMRDEIEFHKTLGDRYTAFEDALDQKEYDETRQLWHTPTELFRPYYGQSIADYLISNYKISHYPYDDLIIYEMGAGNGTLMLNILDHIRAKDPEVYARTKFKIIEVSANLASLQRKNISRSIYAGGHRERVEIINRSIFDWDTYVPSPCFFLALEVFDNFAHDAISYDMSTHKPLQSMVFIDGEGEFYEYYTPKLDHLASRYLRLRRYISPPETLQFRMQRLWRSCKSLVPFTEKRTAPEYIPTRLMQFFDILYKHFPAHRLIASDFHTLPDAVSGINAPVVQTRYRRRTIPVTTPLVHQGYFDILFPTDFNMMAAFYEHITQKFPYVLSHEDFLRRWAYVEDTQARNGDNPLLTWYKNTSVMITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8E6</accession>
    <name>A0A6A6P8E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_337350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8E6"/>
    <dbReference type="OrthoDB" id="5419542at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="474" mass="51403" checksum="D6D5636448308437" modified="2020-06-17" version="1">MDSPNPAAHLDLRKELPLRRSHTALPKLATGVRPSGQTPQPQPQPQPQPQLQPPSDAHHAPGGSSSSSRKFHRHHHRAHSSSGDKDAGSDRHHRRRHQRERDKHRDRDAQQQQQQYGHHGGGSGEGGSGGPSAGTGAGGGSGGGSGGGSRSHYYARDVVASAIQPHAPVSFSDFLKQTASRTGVAQGGSGGSGGDGSGGGGRDGSALAGRSGGAATEGEADVKDNGWSQWGFDTAPVVRPGDLEREKEKERRREEELQTTLSALSALSFRTTRQLDDTYYAILEKAHSIQASVDALQDLTDAARHLRRDFDSDADTLEADIAHQIDAFGGFASQLHKVEELEARMKTSREKAEELKARLEKAKEAVTERERKDEEWRAKVIRRLRILWGLLGTVAGLILIIVIIHFFEEHPHDPFPDTPRPQSKDIENLTVPDSVKDILYDIQEGKPLSSSTTPSAAAKSPDEENKVFRILDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Q3</accession>
    <name>A0A6A6P8Q3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Q3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16998" checksum="629853BFC05BA6FD" modified="2020-06-17" version="1">MWKGFHHGKSERERGLKGSKVRKHSTDLRDGMLGAELGQPQFVVCRVGDSHHDDAVSGGVAHARVERVVVSTRYCLVATVLQGPGHDEKAPAGGRSSVKRQLLAYLDGLADVARDDKDPRRRARWNISEGRWRRVRRRGLAETLHLPVPASPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8R0</accession>
    <name>A0A6A6P8R0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_162303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8R0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="63595" checksum="75E4BCBFBDE5F3A5" modified="2020-06-17" version="1">MKSRRLTFVSLRSPAGVSGIARDLGFAGKRVSSCTAGLVPSTTLSKTLGCCWSPQSDGRAIARAGLATWVRDAVTTLIAGRADGGGGAIFIFIVIVITISGTTHPPALRAAPPLRRPHQRLRRRLGARFVTDISTSGAATRAAAAASTPFQLLSGQHRRAVRPRRLRVADRDVHAVQDAVHRVRHAIVDAGRRLVPFVAEVDVAAEGVGGRGRRDASRRGRGRHRVSGAGEMGESWVVERLLSLLLLLRVLRSRERAGKEWVGVAFRRVLLVVMVGVVMGVGSRGGAVVLLLRRGQRRVHGHKVRLPLVGEVAVAPEARVDRDEIALLRGEEVGRAAREEDARLWRRRRRRRRRRRGGHVSLKPAASALRCRAVRRQIARLVVKGPRRPRRGRRGRHLRQRQPRLRRVRLRLRRLRRLRRLRRERQDGRIDGAGPHPTLVHGRGLGGEVWVGTKRDGKLEQCGITAAAAAASNRSAVRATTGMITASAVRARASMTLAEIGGSVEEEVENVVLLERKERLAGRRDRLRRIACLVFGAMERVCKRDFDFVNVRPRSFFLPSSRTDGAGKNWHKSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8X4</accession>
    <name>A0A6A6P8X4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_162032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8X4"/>
    <dbReference type="OrthoDB" id="5365129at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="326" mass="34816" checksum="D8384C5BA68F598C" modified="2020-06-17" version="1">MAIDVIGLAGTLATLISLLTDNSPASERGNSMFRTTVGLDGTPGSNGGELSNAGGDAPAIIAINRNGDEVGRTGPAELILDHIDDADSLNAEIGQGPDHSGDQAVAAYFLAGNDAICVVSIIVTWPNQLRRGWIGDNGVPCGQFVFPSGVIINDENYEPYCTWLDNDHSNDIPSSGVYIDFREFAVPDGQSLPEEESTTFCGEPAQVFADNAQKRRRSAGAGPPLAGRAVNDTRLVVSGSTQHMAADVCAGENTFGPDYISLADGMYCDMSTREVMPLCTDDLVDDCFDLDDMDPEVSRSKVKKRGLRSTGEYSRVMDWRQLRRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9C3</accession>
    <name>A0A6A6P9C3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fructose-2,6-bisphosphate 2-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_166871</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="2"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9C3"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000005">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="8">
        <location>
            <begin position="33"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="254"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="456" mass="52445" checksum="30622FCB706DFA2F" modified="2020-06-17" version="1">MAPEANGVYKPEMRRVPTGEFVKPSRKTNGVGVQSEDTRICVVMVGLPARGKSLIAQKVVRYLHWLSIEAKTFNVGQYRRSDTPTPTAEFFDTNNPEGERLRRAAAEAAVQDMCKWFSEGKGLIAVLDATNSTKTRRRWVQERCAAENIETLFVESKCDDEELIMNNILEVKTTSPDYVGQDPELAAQDFRKRIRNYEKVYETIDEDEADLTYVKLINVGHQVVINQIQDYLQSRVVYFLMNLHIKPRSIWLSRHGESKYNLSGKIGGDADLSDRGEAYARALPRLVAQSAGENRKLTVWTSTLKRTNQTARFLPFEKLEWKALDELDSGVCDGLTYAEIEERYPDDFRQRDEDKYNYRYLGGESYRDVVIRLEPIIMELERSENILIVTHQAILRCIYAYFMNVPQERSPWMEVPLHTLIKLTPKAYSTNEERLRADIPAVSTFREKGSSARHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K3</accession>
    <name>A0A6A6P9K3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K3"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="38"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="35315" checksum="298C22AD4B14D02E" modified="2020-06-17" version="1">MWSCRFTSQQLRATLRYRRSGRPLWRRAFTSVPSDAWDSHMHVIDPVNFPLSRSATYTPHTALLAEALENAAKLQLPNLVLVQPSPYGLDNSCLLDALDRVGPDRGRGVVAFDPASTSLQTLRDWHERGVRGVRVNLKSVGREMEPKALVEMLRSYVEAIRPLRSWVLELFVDMSVVPHLEPVQAELDGIKLVLAHLGAPARLKWPLHDMPGWSHFRKFMENPDFYVKVSAPYRLSKDPEFRDLEGLVKESLGARGGNAVLFASDWPHTRFEAVDVQPWITKCLEWCGRDQALRDKLFRDNAKILWDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9X5</accession>
    <name>A0A6A6P9X5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Centrosomin N-terminal motif 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_335827</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9X5"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="5">
        <location>
            <begin position="208"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="133"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="335"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="498"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="228"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="545"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="608" mass="66983" checksum="DD1DF770CE3CBC1F" modified="2020-06-17" version="1">MFPPRLAPPRPSLLRFNSLSYARRPRPLHPLRSARSQLGSRSINTDIFRCLSTRPAKPVKTRLPACLVPRRPNTSCLLGPGPANMERSNSSATPANARDVAAATRSGTKSPAPAFVSNPPVAKSELLREALREKRIGSKSDVQARRGSWTPKPTTPKPAPPRDDWIVNSEEEERSDSARSRHHHRRASTQAVSTPRPSASTPKPMASKEADAHMDKLSRENFDLKLRMYLQQERIQKMQQDLDEALDKLESLGKVEAEKNNLEEENQSLEVENEALRESLDAANREKQETLDMNDELVRELEKRDAAVEEAAGIIHGLEEEVEVLRRSTAENRVGDSDYFSGEADNNTSHQLKTTTSNLTASRPSSSGHGSDYFSATSMSPHAPFRTPRSLSRRGQIPQRSSSLQSMQHPDQVGSNKNRHSLHAGVSVGSLASSVVSEQSKAQCLAARTKDQQTFKPVADLAMMTASRLLPKSNGPALSRSPSKPLRSLYRDGQIKHDLPQQSSANGPHPQHLTPHKSTSSDTPASSLRQESSPNANPDDDVFSTDGTPSLQVPSTASSPTLSSVQNFGQWAPPEYPRWPPPGGLLARDFLFNGDGLDDFPRRWERRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA18</accession>
    <name>A0A6A6PA18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U1-C C2H2-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_376612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA18"/>
    <dbReference type="OrthoDB" id="191651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040023">
        <property type="entry name" value="WBP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173:SF10">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-C C2H2-type zinc finger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="294" mass="32565" checksum="5B03A808FDF3A6EE" modified="2020-06-17" version="1">MAEYWKSTPKYWCKFCRVYIRDTPFERRQHDATGRHQSAIQRNLRDLHRDAERSEREKQRARDEVARLNGAPTGLSSAADGGAVAGRKPATERGARGAAVSADERKRQMMQLAEMGVAIPEEFRRDMAMAGEWTVVSEKPVASAKAKGEESENPEGKAVGVRKRKVQDEDEEAVEGASGEKRPRKVWGSTLREYPGSKGKEDVDIEALLGVASVKREEVKKEEEEEGGQGESKEEIKQKEDEVKKEEPADDGAPPLSSIADVGERPHKPVKAEEGAPAPTGGVVFKKRKHKGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA52</accession>
    <name>A0A6A6PA52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4-coumarate-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_335005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA52"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="41"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="459"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="551" mass="60324" checksum="2A03CDABDDC5AA82" modified="2020-06-17" version="1">MVFQQEKSIDLPNVDLLTLLFDHELCDAKELSVIHAEAADPSYSITKAQARKLTKQVAHSLRTHFGIGANGAGKDVVVTISSGQYLLPTAFYGIVAAGGVFSAASGSFTAAELARQIKDGDSNVVICCQYTKDVAIAAAKECGLGLDRVLVLRSYPKMSLRSVEGDLEMFGQGELDWERITDPQELKDRLICLLYSSGTTGIPKGVLISNQNLVAETVLPHALWREANAKLEAEGQSPFESRTLGHLPTAHIAGLQTSFINAFYEGGTVFWVPKFSFPEFLKYHKQYRLTIIVTVPPIYLLIAKMPDVTDQFDSVRLAISGAAPLSKELQYAASMRLGKGKTFISQAWGLSETTGSVTLLAHDKKDLTGSVSPLMPNMQMKVVDDDDNEVEEGERGEIVVKGPLICNGYHNNEKATKEVLRDGWLYTGDIGMLRDGLIYVVDRKKELIKYKGLQVAPAELEGLLLSHELIKDAAVIGIDTEETEVPRAYVVADKEKVSEEDIKAFVKNNAASHKQLRGGVVYIPAVPKSASGKILRKDLREMARREGNSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA80</accession>
    <name>A0A6A6PA80_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_133508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA80"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="85" mass="9583" checksum="5CC36E6C1FCCBBB2" modified="2020-06-17" version="1">MSKVSDWSCIFFPCFLFLEHATLMIYIQSTPSKRCAKTTDATTCLLPLFPCLLYVLLEVISQIEQLIPLTIYESTSETIGCRAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAD8</accession>
    <name>A0A6A6PAD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS sugar transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_133197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAD8"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="18"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="525" mass="58023" checksum="9FD571C5B3F2E3D4" modified="2020-06-17" version="1">MGILHKFLPPEDRFAALMLYGMTFATCFNGYDAGIMTVILADDQFNEYYHVDSDRRGVIATIPWATTGLAQLCVGGTLANLVGRLWALRISIFVMCIGVVIQVVPNTYGVLLFGRLVTGLGFGCVYIATNLYVAECSPTKLRGSFVGTVSQAGYQLGTLIAFWAGYGMSFHTEPYNIAWRVSNIIQIPIGLFFMVLSFWYPESPRYLFEKYPDQPNRCLNNLAKIRSGTPTSEHVQAEFHEIVASYEYRRRFDPGYMGLIKNPALRKRLCYGLYATGLQQVGGIAAVTMYAALIYESLGWNDGNQALAINGIQAVLQLFIVFVNTFTVDRFGRRALLIAGFAIQSLALLILSSLTTSFPNNGNKPAAVVEVAMLFIVGLTYCWSNGPIAPAVASEIFPQHVRDKAFSLSLLGQTACLLALTQPWPRFNEEVGPKSYWLLFSLNVAAMISVILILPETKGITLERMDKLFGEVDAVEAGERDAEVTKIEEKTRETFEKVVGDHKAAGTPEKSSREDKAPKSHVENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB56</accession>
    <name>A0A6A6PB56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_170731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB56"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="181" mass="19724" checksum="5C7B9DA63D6CA265" modified="2020-06-17" version="1">MRVVAAGAPRAAVPGVIPRPVALPAQTRTATKERRGFEAPPRPGRANAQNTFPPDGAALLCPARLARVARLALVRSASRLAFASPLKRCPWRRFSSRPSYLLVRSSSHDPCLRPIPSFVLRIHLRPPPPDLSLRAFSATPAVWSRGELLSLDAFPTVVFTARCLILCRTTASQLRDSTANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBU7</accession>
    <name>A0A6A6PBU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_331923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBU7"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12854">
        <property type="entry name" value="PPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="785"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="820"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="885" mass="100391" checksum="2EB90110D47B5D60" modified="2020-06-17" version="1">MPSRALSKLARLANAAELPIFPFLAPRAFAPFPRWTSNSSQKRPNSSQVAASTPNTNELHQMGDYNGGLGDDTLSSARSSSYDNEGAHRARQPAGHRSLDESKFKSDKMGGNKIEEMGLYGVLKELMGDVGEMDNFKRPHEVDGLERTRPDEAKPPRESQRQNSEAVTPAWDRAILDLKLRAVELKSLQEYNESKLRQKYSKRIIHRTSDIEEKWRMIEIRKRGLSQLEKWRVEEKRLNLLREWLQQGKAFKPGFVPSRYDNTRRNFHESWIQTYAPIEAEQNPLLKDLRLDFGIVADPAAQSWAAELLEYGCRAGAIRKRWLSMTIEKRGKRWPHIMGFLLRNNTSVAWEVLRGTTGYDDMPPAYAICECLRHIVDDLYDDSSTTGSGIPHEFMAQFKTFWRWNGHARPLLHMMTAMRLILRANDAQARTLANMFLEYASFKQLRAMVLWFSERGNPELAVRALKQLKIRGADLSGADVDQWPVQVACMKLFHSVITKRGYQESASVMQQVMELGVSINVELASFMMDSAVEAGDFSTALGIYNLMVDTKLEVNGFVYSILLKGAKKYAEPDMLRNIIALCMEKAHYLECPRTAAEVLHATYLTLERGQHPDFFDLMLKTYVRYWDEAPLCKLGILPEKGENAVPTWEDMPAIKKLELPVPALAVMLFSYLRHPPQSSSVWDAVRVYTNFRRLASEGHPLISKLASESAMPHHAFLLAFSHSPQTLDSMTTVLTDMLASNPSVGHDSSARIEEATFPKGDLSCGITSSDEGAMKRDPPLHAAPRVETFAIILRAFNRWGKWEASAKVRDIMKRRGIEPNQPTWTTIIHGLCASGKIDEAVAEMREMESKGYVVNEYMLKALGMGRNQELLMRALKNSYSCHVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBY2</accession>
    <name>A0A6A6PBY2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RAD52 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_278793</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBY2"/>
    <dbReference type="OrthoDB" id="206565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.80:FF:000001">
        <property type="entry name" value="DNA repair protein RAD52 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004585">
        <property type="entry name" value="DNA_recomb/repair_Rad52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00607">
        <property type="entry name" value="rad52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00077224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="24660" checksum="52F318D151B369B6" modified="2020-06-17" version="1" fragment="single">MLIWDCHTGPSTDALIVLYSPGAQYGDIANPFLGLNSSGSDAPRRMSEYTPQEIATLQSRLHKQLGPEYINSRPGQGGGKVHYLKAEKAINLANEVLGFNGWSSSIQQVQVDFVDVHDGGKVSMGMSIIVRVTLKDGTFHEDIGYGHIENCRGKAAAFEKAKKEAATDALKRALRTFGNVLGNCLYDKDYLNRVTKMRTGPGCWDPNNLHRHPEYAPQAPKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDA5</accession>
    <name>A0A6A6PDA5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YDG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_4496</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDA5"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="273" mass="30335" checksum="EA69EAB0DC111BD4" modified="2020-06-17" version="1">MSSISWYINGALAVCHGVISPQAASGGITFDHDRAYAVVLTRTDEETSDTPEQFVYLTNARAPGIFRLIKAARQEPRPGEQVGVRVYRSHAQSSNRWAPQCGVRYDGLYSVTGWSIGPHPPRGEVTPPVRVHFSRFSGQESIVRALKRPLKEQKDDYKAYIRTRKAQLEARAQQHVPSSLATSRAISDRYETESIETLDVERSETSRVNASLLPVLHAPGLVAPRLEGTIDVDFDMHVVEEKNTSGPRSSEAKHDEAKKGLEGNPRKEIVHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDN1</accession>
    <name>A0A6A6PDN1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_368226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDN1"/>
    <dbReference type="OrthoDB" id="4991875at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40640">
        <property type="entry name" value="ANCHORED GLYCOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40640:SF1">
        <property type="entry name" value="ANCHORED GLYCOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025575885" description="GPI anchored protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="21069" checksum="F5395413282D35CF" modified="2020-06-17" version="1">MFRTLPLVLSALSLALPFTAAQSDDSTVVNIFLVGTDPQDLVASAVTVDGSTATLMVGCPPGTNSEDCGFESAVPITVGSGGSVVEEFYTAPSGTDSTFSASCSVTGTTEAVCAVSEGGVDANLPGETTVTLSGSDVAFLPVTVTAGGAQLQGVFQASSGASSGASATATATATATEDTADGTQTGAAQSTSSDDAAPTNAIVGGSIAGAAGVLLAALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDU8</accession>
    <name>A0A6A6PDU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_267842</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDU8"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="13">
        <location>
            <begin position="6"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="12">
        <location>
            <begin position="494"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="165"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="799"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="810"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2462010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="888" mass="96730" checksum="FA93AD66A98CD28B" modified="2020-06-17" version="1" fragment="single">MTANLTVLTTPTADTPGTTLVLHTDDKDYLFGHAGEGTQRLLSNVQGVRWNRISEIFLTGRVEWRTMGGLLGLVLTLAGVLIESAKSIAKAGRAKRGTGAAVRTSIDLFGPGNLTHTIAAARRFIFRTGMPIRAHEIRDEPPKRDEDGKWLPSWQDHNLRVWSMAVPPTPSTPKEPVLQASTRRKRSFNEVAADDPGRPETESERQDRYDQMRHSIVGDMFNSNWRLDALVETPLAMVKMPATIFVRNPETKMIEKYDGPAPGGKEPLPDIEVLVRKPWPGALITQLPPTQPWREAVSYIVRTPPRRGKVRGQVAKDLGVQGNQFGKLVTGNSVEIAGRTVTPEMVLEPSRPGNGFAIIDIPSPQYVRPLIERAEWRSAEVMEGVGVFLWCLGPGVGASPELIDFMKQMGHVKHLVSSSDYCPNDLPFLGSANQNLLLSQIDPKHHRASYYDESQLPQASFLDPTPANGHPHPGSDIEVITLGTGSSQPSKYRNVSATLVRVPNHGAYLLDCGENTLGQLQRFYDPEELLQILRDLRMIWISHLHADHHLGTVSLIKAWFNAVHGGIPAAPHVSSGPAADGEMFDPAARMRSFRHLAVVSHKHMLAYLAEYSEVEEFGYSRIAPLHITNAKPWGTEGEPEVSTLGWADIHTIYGEENRYRLGPAAYRTLLGLEDIQAVAVSHCTGAKAVALTFPDGAGKVAYSGDCRPSLPFAEIGRGATVLIHEATFDNELAGDAIAKRHCTTAEALKVAEAMSAKGVVLTHFSQRYPKMPIVRVDTDTQGDAGEKALQDLAAVNEAADEDGDAPVDNAGGAPQAAVAPTQQQQTSDSRPQSRAESIASAGEGGGDAKAVLHVRSRDLKICMGFDGMRVRAGEIGELQYYTPAFVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDW5</accession>
    <name>A0A6A6PDW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enhancer of mRNA-decapping protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_368279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EDC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDW5"/>
    <dbReference type="OrthoDB" id="10030313at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612:SF0">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="7">
        <location>
            <begin position="385"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="YjeF N-terminal" evidence="6">
        <location>
            <begin position="604"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="426"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="899" mass="94199" checksum="A28F21A00456E350" modified="2020-06-17" version="1">MASAFIGMPVFVTLNGPQPSTLQGTVANVIPETSTLMLHDVMFLSTGERRPTYTVDGTRIADISIQGSSSLPERPVQNPPPQPVPYTNQSAYPASYATVHQSAYPLQTSLPPRPGDQTGDPTPTQAKPNFVDPAILSVGKKPRATPPAPTAPAEFPSTPIKPHKAASSSVPVAAAATAPSRPGNVGQGDQNVKRAAAGKGTKGAKTGKGDVGATLSAPFSSALGSAGEALDDSHSGNDEPSARKEQRGAGAQEENASGSVRRASINRTRTGKLMDQPEKPGADGGKKSRRGNKKKKDPWSSALNGTDFASSPEVTKKIGESDGVSPANGTNRAKGWRQTPILQDTTSARTTGAATGKTGETAASGKKGRRRRQKGAADVQNGWATEDATDIQELPDFNFEENLSKFDKRSVFDAIRNEDTTADEDRLVSYNRPARPGTYGGKNLHPSENVLEGTRASRSLRRRESSSDTTESSMEFDSGRNSRRALSRASLKRMPYRQNSGTTHIDEGSGSVPSRSARASIARPNVYQGGSPINSRGSPTGSPSISQSHVQPLGLPHHPSALSHHSHSNVLDATSGLSSTSRKQPHLRLATTNRPCPTLTPGTAAAIEELAEVELGLSSDILAENAGRGIAEVALQAINPGGRRLARENLLLNARPVVVVLAGNHRAGARALAAARHLAGRGVRMLVFLVGSSRTAESADSDVRRQADLFRRQGGSVRGWADVRSELRRADAPPELIVDALLDPARGLEALGQEDRDEAWDAVGWANKSAAAVLAVDTPSGVNGSTGEIAIREGEPLEVRARFVVGCGAVRTGVLKAKVHAAASAAADTATAAARHGQMGGSGAAMAQQAANWLLWVVDIGISKAWKRRGIAGGKRVRFGAEWVAPVAFVGDGGEEGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF54</accession>
    <name>A0A6A6PF54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_12026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF54"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="196" mass="21103" checksum="EEABDCBF67FF10B7" modified="2020-06-17" version="1">MNNASVTETHLDIRFTGNPTNRGALQFPAERKTKKKKKKKKEFPPPNLQIPDDDETQRRPPWTARLARPRPVLIERLDHSLLIRRVDGRRGGAVAEAEDGLDDGELGGGGVEAGDGHPVVDDDAGADDGAAAVDGAGDERHLEQRRQLVLVLHRRLGVHDAALVAEGHVRAREDVVGDGLAEDFDAEDVGDAGGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKK7</accession>
    <name>A0A6A6NKK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_359707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001715">
        <property type="protein sequence ID" value="KAF2452270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKK7"/>
    <dbReference type="OrthoDB" id="5062908at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="141" mass="15996" checksum="E8B0653F075123C0" modified="2020-06-17" version="1">MYQTTLGEDELYHCPFEGGHQCKHKPTKLKCNYDKYVDSHLRPFKCKNAACSGARFSSTTCLLRHEREAHGMHGHGSKPHLCIFPGCERAVPGKGFPRRYNLFDHMRRVHNYTRRALPSEAELSGSRAGGKGARRKRKALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKT8</accession>
    <name>A0A6A6NKT8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_388691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001713">
        <property type="protein sequence ID" value="KAF2452288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKT8"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="43"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="225" mass="25979" checksum="12DA7FF00A2C68D0" modified="2020-06-17" version="1">MYIDLEGVDLCREGSLSILTLLIDTGIPTIRVCPIDVYSLGSQAFNTTGIKLKTLKDILQDKKIPKVFFDVRNDSDALFAHFGVTLQGVEDVQLMESVTRMTTRSRKYLNGLAKCVETKEKGERFFKTEHWGSSEIFNQRPIPNDIISYCVDLVNDKTKKRVTTSQKPEYQPHGPNRTLAPWSEEQNRTLDEWNHVPPPYDYFDDDYFNDDCFDDYWDDGRGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL54</accession>
    <name>A0A6A6NL54_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_294801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL54"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF16">
        <property type="entry name" value="GROWTH REGULATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35468" checksum="6548A4531AFAB0D5" modified="2020-06-17" version="1">MATAGGPASIITQVSQGGGPPINTLAGNGDENITLDLRGTRFNLSRDELLTLPEFVLLSLFPNGLLPDGQMNSFQQDGDVYPVDYDPASLQYMLDFFRQVAQSIESSTSPPSPSDANHHGHGSEAIPIEPMHGSARDMLQDRAGIIVLREDLDFYCIPPRRDVEQPEMLDIKKAAGRALIRQDGIFSGLRKSEEPGTTEQHLIEMLTAGGFNHDDRWGHRTTEPNKAVICSIALARLRTDVKNVDTQTVNNAVGMAQKLLLFWRKPARRCWWEGVDLEGVEGVEGTLKCWIRRVWTLEMVSCLFSLLASFLFGRLDSVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMF1</accession>
    <name>A0A6A6NMF1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase epsilon subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA polymerase II subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_312229</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMF1"/>
    <dbReference type="OrthoDB" id="1707486at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22928">
        <property type="entry name" value="HFD_POLE3_DPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051377">
        <property type="entry name" value="DNA_Pol-Epsilon_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172:SF1">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="121" mass="13177" checksum="66347C2299E03EC1" modified="2020-06-17" version="1" fragment="single">MVQRLAKGVLPTNTQIHKDALLALSKSATVFVNYLSSHANENASRTGKKTIQPRDVIEAINELEFEPFLPRLEAEAEKYNAIQCDKRNTYRRRVREEKAAAAAKAIAAAAGSTAATSLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMM5</accession>
    <name>A0A6A6NMM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMM5"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="56"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="32962" checksum="21219B51E2848337" modified="2020-06-17" version="1">MSGDFATPSEIFVPRQATPISPEVYHYLTQDGTVRVAAHIFSNMLPPLPADAIIHDVGCGSGEAIEGLMRSGPPPSIKIYASDFDTNMVAACRAKAAREGWPLAGRPEEAIRHLDAANLAGVPDAAFTHAIINMVLHGLPEGEPEKAAKELYRTLRSGGVGVVTTGRRTLGIPTIARTSQATRGKGVQLKFPMDDMVKWESGERLKECLVSGGFRPEDIKLDKCQSVMWLDDFKKWTNALWSLLGRRAGDNDWMQEDEDKWDEALDFLMKQIQESDLAEQEADGRWKVSFIGNVAIATKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMR3</accession>
    <name>A0A6A6NMR3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_294145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMR3"/>
    <dbReference type="OrthoDB" id="4898680at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="718" mass="81154" checksum="CB2A397B08C979BA" modified="2020-06-17" version="1">MFRRNGKPKSCEPCRISKIRCDHTSPTCLKCSSRGMVDRCYYHAAPMTKPRTKEQKRAVISPMTPSDTPSVEWEQLAPGPIGNQTQPGETVHSGYLGATSYASIFQEDMYDRLRLNAQLAHIPNSTAEGVDPYASYRFEVEAKIIARLFPHSLLESLVKAYYDRGVFNISIAPLVIPAIPKVWDYIDRQLEKHGGRIDFSLPRKLNENTARPFKVPPDTSPSDFLHLFTGENLRWEFIGLIFALAGVGALACREPEANFTVDGGRQLPRNEFVGETITAAEVCLDIFRRHGETNDLSIMLVKQLTYTESNYYGDSNAKVWRGLGECSTEMFALGMHRTPDDDPSMPFFLKETRKRVFAAAFRSDKILCTFLGRPPRIPYRYCDFMMPLDLSDDDLVAEGEQLERALAQLDSDGWDRRPNRKVHSSSWVRMRYLMSIVREDVLELSLAAGKKDLNIHERLNLDTWNTFPQILRYTSDSWTKRPPAECSMLLIVYLEHLHTSFSIERLRRRVLCKQAAPSARECPTELLRISLKLVQTTLDLIRHSHGLSEVRRNFAWILLFYGLAPAGVLATELRRTTMGTYPFPATVCRAELIRNLCVLVSCLEWVAVPGTCNYKLCYQVSGALKDIVDQALGCKYISGEPSTLDPDAAAESSTTARLANGNSHEIAGVPNGAIEKDISDDRHTFGDFGEFDASQVPMETEDFLNWLENMEWDNMPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNA4</accession>
    <name>A0A6A6NNA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Eukaryotic rRNA processing protein EBP2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_328153</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNA4"/>
    <dbReference type="OrthoDB" id="443772at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="418" mass="46567" checksum="9356158E38BC1FDB" modified="2020-06-17" version="1">MAKGSKLKKALDRHQGRDYELEKQKKLRKEAEKRKQVKGKKIEEEADDITDDAETSVRGARRDSEPGIEAEVNGASTNGANGENGEWETEKSEEGSVEDDEYEHEEKFDLSRLDDSDSSSDEPVRDASEDGEEEDAAEEGSIPLSDIESLASEDKGDILPHRRLTINNTSALLRAYKSIALPLHKLPFSEHQSITTDEPVHIKDVDDDLTRELAFYSQALSAARQGRDLLKKEGVPFSRPSDFFAEMVKSDEHMGRVKQKLIDAAAGKKAAAEARKQRDLKKFGKQVQIAKQQERERAKKETLEKINILKRKRQNADIPNANEDDLFDVALDDAADSGRHGKKSNTDRRAAGAAGKPNFKRQKKDEKYGFGGKKRFSKSGDALSSADMRGYSAKKMKAGPGSKKGNQRPGKSKRAKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNG0</accession>
    <name>A0A6A6NNG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="13">FBP aldolase</shortName>
            <ecNumber evidence="5 13">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_356281</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 13"/>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNG0"/>
    <dbReference type="OrthoDB" id="35652at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="267"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="288"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2453300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="360" mass="39707" checksum="2F93446A0C89F2B6" modified="2020-06-17" version="1">MGATDALERKTGVIVGDDVRKLFKYAQEHNFAIPAINVTSSSTVVASLEAARDSKSPIILQASQGGSAYFAGKGVGNSKQEASISGAVAAAHYIRSIAPIYGIPVVLHTDHCAKKLLPWLDGMLDADEAYFKLHGEPLFSSHMIDLSEEPVEWNINTTAAYLKRMAPMKQWLEMEIGITGGEEDGVNNEDVDNNSLYTQPEDIYEIYKTLSPISPYFSIAAGFGNVHGVYKPGNVKLHPELLSKHQAYVKEKTGSDDAKPVFLVFHGGSGSTKKEYTDAISYGVCKVNLDTDLQWAYLTGIRDYVLNKKDYLMQQVGNPEGPDKPNKKFYDPRVWVREGEKTMTKRVCEALVDFNTANQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNG3</accession>
    <name>A0A6A6NNG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endo-1,5-alpha-L-arabinanase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_403740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNG3"/>
    <dbReference type="OrthoDB" id="3879658at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08999">
        <property type="entry name" value="GH43_ABN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025495103" description="Endo-1,5-alpha-L-arabinanase A" evidence="9">
        <location>
            <begin position="22"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="7">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="350" mass="37532" checksum="D89B3A1051B85467" modified="2020-06-17" version="1">MVISKATLTTLLVALTTSSLAIPISESSSHANKARQDGTCHGIVGPVLNEFPDPAFLKVDNTYYAYGTGTSSRNINLARSTDFSNWTPLPTDPLPDLSAATWTSPDPSFAVWAPDVIRRASDGRFVMYFSANDAGAPGQHCVGAAVADAPQGPFVPEPQPLVCRRSEGGSIDPAGFRDGEGGRLFVVWKIDAGHVGGRTKLLMREVEGGGAREGLDFVPGAPTRLLLESAAEDGSYGIEAPYVFERAGTYFLAFSSDFFATPEYDVQYATSADLDREGQWDRVDAPLLESGLFSECASLNGPGGASFGQSEDLVLFHNRHNSTVPEEEGEVIRGLWAARFRVDGERLGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNL1</accession>
    <name>A0A6A6NNL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNL1"/>
    <dbReference type="OrthoDB" id="10266568at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="21675" checksum="A499E847200C50DA" modified="2020-06-17" version="1">MSGLEKALFNLKFTAKQLNRQAAKAGKDEQAEKGKLKKAIQQNHADIAKIYAQNAIRKQNERVNLLRLASRIDAVSSRVQTAVTMRQVTGSMANVVRGMDSAMKSMDLDKISAVMDKFETQFEDLDVATGYYENATSSATAVGTPQEDVDRLMNQVADEAGVELHQDLEAATPAKVKPTPTEYEEEGLGDRLRALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNT1</accession>
    <name>A0A6A6NNT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeo protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_388206</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNT1"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="39"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="41"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="387"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="592" mass="64893" checksum="E15745D211495A2D" modified="2020-06-17" version="1">MSSTPSPAATSAATPTHPPLSASSNSSRRPPRKSTLTQQQKNQKRQRATQDQLVTLEMEFNKNPTPTAVVRERIAQEINMTERSVQIWFQNRRAKIKNIAKKSIENGEDCSEIPESMRKYLALQAMESGKGLGRDLLTRAGGPYGNPALFFNSESSSTKVVIHHFTCRSLSIGNWRRVGQSAMELIIFYSPEKCCVTYYINNDSAGYKIEYPFSYIKTIQLDNGDGQNNAEGASQRLGGIIVELTRPPNFFMDSSGSGFYQCGDFTEDQQASQVMVHHLGGHPKVLTGQLAKLVSLESFQNRHKPNFYDPNALAASAPVSPINHRPASQPNHVVHPHTPMFQEPYGPGLHPPRGHKRQRSRSVPVAVDFNMLRQHPMPSFLIQQEHQAPSPYGSNPNPSPNPEIFAPVPQHGMPTSAGPMGPNLSIDTSAGYGMDYRQYPMSATTANSPSEYGTPAFFTSGAQSDNVQAGNFNTPYNAHFLSPMPTDPNGMPQSISPMPSMGHGDPVIANQSPPLSSLGRSGSADIFPMPNEHGGLPDDGLSLSEMYSKSLTLPFRSPMEEEHNPSELDMQSYVQFGAVNPESLSPENVPQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPL6</accession>
    <name>A0A6A6NPL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_123723</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPL6"/>
    <dbReference type="OrthoDB" id="3061561at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025502768" evidence="3">
        <location>
            <begin position="19"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="534"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="587" mass="66107" checksum="8832DE5C5D23ADAD" modified="2020-06-17" version="1">MLFLPLLFCALVFRRSFASPITSSRRATNPTDSDPPWVESPDIRGTYDLVLSCLTTLSLCAWTAYHPNVHPQNSMGRTFLRRLWWMTVAVFVPEIVLFCAWEQCWAAKRLRDEVNRLSGFPVGTQKEKDEEANTTSEAKPDENRRAPWSLEQAFFALSGGIAVASDSFWTHSKLTFTPAGIVELARVGHLPNISLETVADKSKANTIAKVLVCVQASWFFVQSMARLASALPLTLLELHILTHIACALCIYLLWMKKPYDVESAIVLDDEDTVDMAALFAADKRMWSRRHEDPSLWMSIRGSFYRKSGKPIKAPRESTESYSTGEHLCRGKEEEQLKRAKRALHKFHCTGNNFEFLILDRPNCSALEPSASESGSSPVVARRTILDDFSPTDLGSLEFRKGYVVRARSNMHLDKIGAERPNDIRHDARNRLHTRQLKVFTLLNAVYGGTHLAAWNSHFPSTVEMWMWRAAGLAIVGAPAVVGMTYGLGIAEQWFERPQTRKEDKEGNDEGKSYEKREALRAPLWRRAVARALEAMLVLSFTFLVVGFSITYPVGRLYVLVESFASLRSPPAGTYATVQWSEFIPHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPT2</accession>
    <name>A0A6A6NPT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_356534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPT2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="120" mass="13140" checksum="4C46C2030C44ED56" modified="2020-06-17" version="1">MKPPIMRCASGERICGPALDSLRPYQYPLTGNLISTYTTADGITAVQKYSASSATNLQVRACCATRRRLLIGLPHYSSPKAIQLPWRSAVSTRRAAKIEPMHRILVVVNDQRSSAAIISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ28</accession>
    <name>A0A6A6NQ28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ28"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="15388" checksum="F7987FB3D6C79B85" modified="2020-06-17" version="1">MGSPTAVVSYAKSCLDTSSPTASASTMTTSSSTTVSAPGASVTTSASCSTTGASNSASETRGARSGLPAGVPTRISSIRSWPVLSSTNSSSSSFRPPSSSLNPPGENKLLLTPTLLLTNLPSLSLSISSHAPSNAPPGGVAANTSSSANGTSADPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ32</accession>
    <name>A0A6A6NQ32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_119237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ32"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="38033" checksum="07BF2A2614FBFB2B" modified="2020-06-17" version="1">MTSAAVDPEHAATHNVEVDTAAIGSDSDSAYDEGELKSYTTSLASSVLNFPVEHGRRYHKFREGSYNFPNDEKEQDRLDFMSYITRLMTDGKLHQTPFPKSAPPKRILDVGTGTGIWAIDAAEEYPDAEVTGNDLSPIQPKWVPPNVQFEVDDVESEWAPRAAPYDFVFARYLAGSIKDWPRLVGQIHRNTRPGGWVEFQDYAAPYSQGGAARPDSPFFRMYDLLTQVIGKMGREMWPGPKLEGWVKDAGFTNVTHKVFKLPIGAWPKDPTLKYVGGLNLVQFLEGCEAYIIGPFTRGLGWTMDECQVLLAQVRDDVKKKNVYYLADYHVVYAQRPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQI0</accession>
    <name>A0A6A6NQI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQI0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="785"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="895" mass="93497" checksum="B084BB1FEF748063" modified="2020-06-17" version="1">MPALPHRRIGGTDPVAARQVSGFLTGEGDSAASGGKFKLVRSGVKVLLYATVLFVAVVILGFLLHYCCTPWIRRKFRQSRNMNASHKRSRTDLQDRVEGAVHEPCKAVLARGSYLLRRASSMGNPKGRPCRCGPALPPSSSKQYFRRSTKLSMTEVCADPTINTFEDMLQALDVDRTIRPHWLGGRRKPQQRPFARPTPVPLASARLAPVPEFAGGQSSPDGTMQRRMRGARSDATTAYRVISAQSITPPPSAQPPTTRLPRTRVFAFDGSRGDEDGERRRGRHARSGPKLPHAKAARWPGSPGRALKRSASSSLLLTGDGIFAEFENIRAGRSSSVPNHSLTNRRGDRDASSKGRGASSSGGGSEGDGGGRGGGGGGKTLRRMKCRKRANVGAINAAPTPTIAPGSYMKMPLTPLLPPRLQPIRRRPRATTAEATPEERPAITCASAALPPCHAANRNSTGNAAPGYASDQVGSSVHAIEPHAATAASFSTARRLPLRPAVPAVEVTSFDGANCPPAAATTTAVVIAPACVRSPSGDSLPSTRSPISLPDLPHSLSSLADGTSTFLNSNHAECSDEDESHRLSSAIAAPSSWTAEADVPAASARPRASAATSSDASASATDIGGGSTTLVADSHVQQRAERALLSAFSSASTMTTTTTTTVSFPPPPAPAPEPFAGLSECGSTQTVLRRPPASPEPQPSVAGAALSGPFCAGDGNDGDAAERGDAPSGARDGRVRAGRGQRPFLAPPSVTHGGGGSGGGGHGGRNPGPSLLDPARVQKQRQREPALPAEAAAAAAAPTPKRQRSRHIRFPQLQLLSRGSLKDRRSRVAAEAGTGERVPREHSQQHSQRPDARNAEQGQSDRGVDGRVAGLRLQGQDGDGAIEMAGRRAKRVEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQT4</accession>
    <name>A0A6A6NQT4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_374391</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQT4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="54"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="231" mass="26099" checksum="1860F57DFABDD73D" modified="2020-06-17" version="1">MRIDLVNTTPDGTVPETDILSYIFDSTADADSKIYIDIDNNELEERAFLTKPTLRTLVSVYAYCLRSKFGIGANGPNKDIVMLLLSGRIAAPAVFYAVIAAGGVACLGHPQWTNAVIADRMEHCGARLLICTEDLRVQVRRTLRMMEMRGQKKDGKLGQTLELCVHGPSVVRKYFNDDSANKASFQGEWFRTGIRAVQAGDGQYFFTKWDPEYRNLEHYQWLGDHEFDYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS01</accession>
    <name>A0A6A6NS01_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_111397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS01"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="27185" checksum="CC3EB8A49C165E7B" modified="2020-06-17" version="1">MTMPSLSAAMIGSGRNACAGTGGLRFGRARLSAVDWRAGSPGSTGEGNRGRGQLSALATRAFWRRIDAEADEEGAINGGPRAGGSRWSPGAQGSLSAPTAVMGFPSTGVCAGRAENRRREAARAVESARPGRLRPGARVGLDAQVFHKPAVLGGGLVRRWTRRGWAAPSQLPSSVRGCGTAGHPSRAALFGAPYQAWRLLLSFLCIPFGTPLRTEAPPPCRPRRRGRFESRHFCCGEKRSRMQQREPRSCSPRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSV3</accession>
    <name>A0A6A6NSV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_351637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSV3"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037507">
        <property type="entry name" value="Ribosomal_mL59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="2">
        <location>
            <begin position="16"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="209" mass="23551" checksum="E236CB50DB76A954" modified="2020-06-17" version="1">MASRQQQIALAQNLPRRLLNFFRKYPPPPQVISAHFGASSIAAGPAPSTPTPTTEAGVSAPPSDTAVATTETSTVAAASEPVDPRTIDLGYHNPFLPKKIHTTGKWQGPRYGLREQADLCKMARKYGVEDLLPWSRKKSGERERRRMEQGLRVKGTGVGERVKGKKWERTLRPRLETRKKAMLEMPQLIEYWKSRGHGKFLPKKMWPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY4</accession>
    <name>A0A6A6NTY4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exocyst complex component Sec10-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_290545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY4"/>
    <dbReference type="OrthoDB" id="5554140at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF1">
        <property type="entry name" value="RECYCLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="939" mass="103788" checksum="A68AB7D045F65850" modified="2020-06-17" version="1">MASGSFKRAPVTGGAAPRHNVLDSLRATQIVGSKPVLPAELIAQILDYLSIPDLLRFARTSRRMCEMVYDDTRWVSRLKAMGLWNDVEARRRAEEVRRRQMEIQKAREPEEEARRLGIVQGQSEAGVLGVGNAQRAGTTLFDAGWEEDRRRQSLEKAKAAQPPLETGFDAMTLSHVAAPNSATPRDPALALKAMMQVRSIRGYARQEYGKVYGAMAPFYFDLARAQSHTDPILFRTYREPEQQASMLASLKVFARSDIAMGWESREEKLESMMGIFENAALREFEQGYGAGDVDGRMRRYAHVLVVLNGGAAAVDAFIQSHALFSESGGLGMLLDCIQSVSPGHGGAGVRLEPAHDYFRRLASSLNEQGAVIDRVFPPSVNVLTPFIERVAEDIISEYITTLFDEAHERSLEAYLKVVPGVFEAAAKFSRSIQPSKASPPDFSNQVAHLVASKAFEQHIDLYLQEELDFFKRASDGEVTAWEKRLDDEQQSTESFLMSNVSRQAAKRDFLTSFRKVVMMPVSVLPTPFAGSAKPASSPNPNLATTSGGEVLSAPSSRPSTPALPERSSSPNPPVSELPTTELAAKAAIMASRLEGIRSLFSIEVALNIIHAAKSSLDRAALFVKFPITQAAGEAREQCEIIFVELLNQLGGRHIRPGFDKAVEHLSHYNPRKLKEHGGNQGQVAPLVTFLELVNVGDLIQQMVDVFYVQEMVAPKLVDRDDFLAAANKEKKRFEQMLDERVAAGLNKGIDVLMEEVEFIAATTQSATDFNPGAAGAVDVKSDAVVDVGPTETATRIVELVSSHTGMLVGSTDKNMLDVFNQEVGLRLFTALCKHLKRQRISVEGAIKLISDTNAYYSYIATLRNKSLTQYFAALRELSQIYLISSKHAKEIATIIADQDRYYGIFRAEEVYEFAERRADWYLVKRDVERAMYGIGCGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU60</accession>
    <name>A0A6A6NU60_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU60"/>
    <dbReference type="OrthoDB" id="2590011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="143" mass="15811" checksum="BCE4C98B4E8505E7" modified="2020-06-17" version="1">MEFVLTLESPCFNHVGNPKEAQHAPHGHALMATAPLLLQAPEAPKALLSSHASWQVPDTGIERLLSLSSNLPLDGDVTPIQAWDYIRKQPGFENLELSRLRELTEKLLNFVKCYGFGSVMGQSDFENIVTDTFSRPTPAGYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU70</accession>
    <name>A0A6A6NU70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="14">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_289711</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="14"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU70"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000235">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000144">
        <property type="entry name" value="Ubiquitinyl hydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 14" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="17">
        <location>
            <begin position="106"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="16">
        <location>
            <begin position="257"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="551"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="621"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="712"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2455325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="758" mass="82044" checksum="89DA0B7D50F31351" modified="2020-06-17" version="1" fragment="single">TGERNHAALHTKTADHPLALNIKRTRKKVQREEPPQKMSKLAIAAETEADRYDTATSVKCYECGVEGVKAAHAGPSSALAAAVDGVLRANTFARQEEVKAWEQELTPCEHTLCLEQEAARAIDARGLGQCSKCNLRENLWLCLTCGNLACGRAQFGGVGGNSHALGHNAEVGHPVAVKLGSLTADGTADIYCYACNDERTDPELVAHLAHWGIDIADRVKTEKSLTEMQIEQNLRWEFSMTTQDGKEQAPLFGPEFTGLKNLGNSCYLASTLQCLFDMPEFKTRYYHPNEAPPAAADPANDLETQLRKIADGLLSGRYSKPDPDVVPAAETDVPHQKGLAPAMFKHLMGRGHAEFSTMRQQDAFELLLHLLKLITRSQHAAEGTGVDPVAAFRFAMEQRLQCLQCRKVRYRTDEQDNISIPVPIRRIPKKAGGEGSEGDKKDEFEPVTLRECLDIFTAPEPVELTCPSCGSSAGFEKRTLFKTVPAVLAVNARRFEVVGWVPTKQDVPVIVDDGSISFDAYMSPGMQPGEEPLPDDADVGASGAASSAKFVPNDNALQMLMAMGFPRVRCEKALHATGNADAEAASNWLFGHMDDPDIDTPVDLSGGGGGAAGIGSGAGATVDPKKVEALANMGFSAPQARQALKETGGDVERAVEWVFSHPDAQGDFGGGDDDAAMHPPQPKKLPGSDKLPANFQLQSIVCHKGSSIHAGHYVAFIRKQVPSDAAPSWVLFNDEKVAKAVDVDEMKKFAYVYFFRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUQ8</accession>
    <name>A0A6A6NUQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_76768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUQ8"/>
    <dbReference type="OrthoDB" id="5144514at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195:SF4">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025674514" evidence="2">
        <location>
            <begin position="26"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="337" mass="36107" checksum="EE42F9935441A41D" modified="2020-06-17" version="1">MYTLTTTAAAFVVALFPATISAASANVYNNCDFDVYLWPVDAYRNPQVPIILDAGSGTYSEEYRTLPYGGVSLKMSGEQNLFGAITQFEYTYNDKIWYDISNVNCHQDECPFQPYGMYMESGADCPKVSCLAANLTCAMAYHNPHDDWATLSCANDDDIALHLCVEDLATVADSSDSVSIDSTRSNDDDSESAPAESSAPASSSASAEPEEPVQTETSAEPAPVESFTVASSNPSAEPEEPAEPEEPAEPEEPAEPEEPAEPEAPETPAAPESTTLSSVVAPSQPEVTEAPVMAEVAEDVDGDILWVTEVVTITTIHGVLGQVGLGFNRRWKIPKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUR7</accession>
    <name>A0A6A6NUR7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_289983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUR7"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45676">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45676:SF41">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="493"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="579" mass="60725" checksum="15C514F2668FB429" modified="2020-06-17" version="1">MTSSLRRRRNGSPSRGRNTTADDQTAVLSRLLSVAAAATALSLIGDNERIHGNDGDESSFNGFLRSLESGRLASTLRQGQGGNDDEDEGSDGQEGVNAPLNFFRMFRFGSSNNQQQSNHSNNSNNNSTSPNTTDAGGANNDVRMIPIIIVGIRSITPSAGGNPPDGDTAIPPFLDPLANFPSPITGQGDGSGAPGLDGFGGIPQPRNGTRFSHMRRRRASMGGLNAGLSGYDSQRHQRSSEGNGRPWSTISDGGAASSRPPSEPFPSLASSRAPTPLAQNRPSSTTTTTTTAPTTPTTITPTLSASQPSRSSEHSVAAPSPTAITGGSGLAPTVEEDWNPQPASLSPSLRSTRRPFQAPHRRLSDPASRFRIPRFGSGSSRRNAIIEPDPPRGVGAGIGAARSWIIYVLGGSYPENHPILTTPSLFSDSPTYEDMVLLGSLLGPAKAPVARREDVDAAGGLVTIMRDTDGGGLVDGEVEGRTIVLRLSAEQQCLVCLEEFVAGELGRKLNRCGHLFHRDCIDHWLTTGRNSCPLCRGQGVDEVPPPPYPVDGTQSGFGSASGVPRGGRGEAEAEAEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUU3</accession>
    <name>A0A6A6NUU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUU3"/>
    <dbReference type="OrthoDB" id="4708870at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="213" mass="24931" checksum="453F1C800746F6A3" modified="2020-06-17" version="1">MRFLGLNPERFERGFDARDDLFAWCASGRFFDQPRVRDRIENSNDRRRARKRDMYRAFVDEWIPAHPEVGAADKGWTRESVLEEALSTFGKEPERDQKLGNLRRKVAEDALFGKIAEIVPKEGAKLNLVMRALKRWVVFVDGEPVVMREAELDPKKQATWSQVVPGEKRERLFKWVEEHWELVKNMEQKRTNKLKGERKAFKAASSVVTQEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUW1</accession>
    <name>A0A6A6NUW1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_270849</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUW1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO/CreE_NAD-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="528" mass="58088" checksum="8C9623FBD45D3801" modified="2020-06-17" version="1" fragment="single">IRARRIAIVGAGPSGIAAAKHFLASRAFAAIDVFEQRPCTGGLWNYTPNIHSEPHFTAPSTDPHVPLEQPIWSTSPAPRAEATTAAAHGDDAIPCTSPSAYGDAAAAEPVFASPMYERLETNIPKPLMQFSDADFAADEPLFPPRAAVLRYLRQYTAGGVLRLVRFRTQVEEVRLLEGNEEEKEKGEQDGISWCEDRWAVRTRDLTSGTVEEKIYDAVVVGSGHFSTPCVPELDGLKEWVRDHPGSVLHSKYFRRPEEFSGKKVLVIGASASGLDISAQLLPYARTPVHLSQKTPSPLSATSKPANPSLQVHAALTALDPRTRTAIFAPSPTPDTAPTPPTTVSDIDVLLFCTGYLYTLPFLTLPASEPSPLHPAGLRLRHAYRHLVFAPRPSLAFLALPQRVVPFALAERQAAALARLYAGRLSLPAPADCAAWEAAVLRDAGDAAFHDLQFPKDWRYVNWLVEWAESADEVEGGEAEAGWEEKVPPRWGEWHWWCRERFPAMRKAFSERGEGRKDVKSVEDLGEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUX1</accession>
    <name>A0A6A6NUX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_289012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the polysaccharide monooxygenase AA13 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUX1"/>
    <dbReference type="OrthoDB" id="120613at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025640269" description="Chitin-binding type-4 domain-containing protein" evidence="7">
        <location>
            <begin position="19"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="8">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="22669" checksum="D2E69AD8E71B3FBB" modified="2020-06-17" version="1">MYFTSALTLATLAATAYSHGLITSPTPRDVGPAGTEACGPVVMAIIESDKTSHVEGLPEASEQDSAYNPAECNLWLCKGLQYEDNVDNVMEYSRGETVHMDVYIRIPHLGTANVSIVDTASNSIVGEPLISWDHYADDALGMNQPESQTSFDFVIPEDLEDQCAEAGACVLQWYWYGDAAQQTYESCVDFTVPAMEKKVRSRHFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVF8</accession>
    <name>A0A6A6NVF8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Six-hairpin glycosidase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_65950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVF8"/>
    <dbReference type="OrthoDB" id="4138492at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41814:SF1">
        <property type="entry name" value="CELLULASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41814">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="42156" checksum="F8DD91475F30530E" modified="2020-06-17" version="1">MRTENGNRRRWEAGQSRAELNTSRIAEQAKVLASHSWEHGTAAEALLELYDPHLSVFGDEPFPADKVPYTPLEETESLSYAKPHILLDAGTLIRDEHATGDPAALGVSAVLIGQSDPEYVKAAWRQAKHLLDSAPRWQNGAISHRKAVAELWADFGYMVPPFLAYYAIVSNEMRYMREAIDQCMLYHEVLSTGSLGKERGLWHHIVGPEKKDLGYWSTSNGWAAAGMARVLATMKKWKPTAAWKEEQQMLVCYIQEIIDGAMRTDDGSGDGLLRNYLGDESWFGEVSGTALLASVVYRVAVLEPEPYGDGSWDGYLAWAHSKRAAVERHVDAATGIAAPAVQPLDHLLREPLMTGSPEGQSFVVLLYAAYRDWSRNGGGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ2</accession>
    <name>A0A6A6NVJ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Clustered mitochondria-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_365051</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1414216at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15466">
        <property type="entry name" value="CLU-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2280.10:FF:000002">
        <property type="entry name" value="Clustered mitochondria protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2280.10">
        <property type="entry name" value="Hypothetical protein (hspc210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033646">
        <property type="entry name" value="CLU-central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025697">
        <property type="entry name" value="CLU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028275">
        <property type="entry name" value="CLU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027523">
        <property type="entry name" value="CLU_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023231">
        <property type="entry name" value="GSKIP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601:SF6">
        <property type="entry name" value="CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13236">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15044">
        <property type="entry name" value="CLU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12807">
        <property type="entry name" value="eIF3_p135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103107">
        <property type="entry name" value="Hypothetical protein c14orf129, hspc210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51823">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Clu" evidence="4">
        <location>
            <begin position="346"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="604"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="671"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="965"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1378"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="604"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="671"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1397" mass="152054" checksum="4519E90B8DB73DB7" modified="2020-06-17" version="1">MASESKNDAPTPTLDAVENTIPKENGDVREDTASEDGAEQHTENVWQLEVKLPHEPYETQIMASPQEQVQDIRQSLVELPHTFQYSCFHLEHSGTPMNDFVDLGEVPGIGPDSVLTLVEDPYTEKEARLHVMRLRELLGASTSRITAGGSATDSVHGIGAGVGLYDQVTPEVPADKPNGQPNGILKSSKPELDVSLDTDASGSVKTVLPRPADPAPKTVKSIAVSAWNPPPAHLRAVGHLLYLALTTLESETFQITAHVSGFYVNRCSANKFDPAPKQSPKNLHAHSLLSLVAKLSPGFDAAFRALQAYNSRKEPLSTFALTNATPPSPWAVPPVSSTSQQGASTGAHQPDIVRSQEAYLLAGADSNETLRDWNEEFQTTRELPKEPVHERVFRERLTSKLFADFCEAAARGAALVARGEVQPLNPNEPRDGQIFVYNNIFFSFGADGVGTFAGEGGDEAARVAVGKDVVGVRAVNQLDVKGLHTPGTVVVDYLGVRVVGQSIVPGIFKQRDAGEQQIDYGAVEGKDVVADNEKFVEPFREVSKRCKVKAHPVWDKEGKRHDLESSVETKGLLGTDGRKYALDLYRLTPLDVAWLEAYWADPPAKEEDKEGEKDEEGEKKAEKRPELEKPREKNYPHRLAVLRQELVNEYHKVKLREFITDPENLALGRKAREEADEKALEEEKPNGEMNGEEASKEVAKKDDDKDDEKDDEASKRAKDEAALLRLVEEDKIPREKAFVDLNPDVFSGQTPQTDEEKAALAKDEEEVRHACTFLMEKIIPRLASDLREGDASFPIDGQALTSLMHKRGVNVRYLGRLAQLAAEAGDDARTQAVKRLAVREMVARAFKHVANAHLRNVPQPLAPAAAAHLLNCFLGERLNGAPAPEADGALKELYGKGDAGYDFEKETPKSLREEVVRQVHMRFRFEIPDGESLVQSGLEMQMLREACLKVGLQIVGREYTFEKAGTSAAEGSDSELKVPESNGTGAGQTGSKGKKKKGGERSPIRNAGVQQTVTFHPEDVVTFVPVIKDSAPKSSLAEEALDGGRMAIAGDAHDLGHELLLESLSLHEQIYGLLHPEVARVYLTLSTLYFSLQEKPLAVELARKSAIVHERTLGLDHAETAFAYLNLAICEHWAAAGNADSNRGGIEESKDALLPAAFSHLRHALELTKLAYGPDHPDQATTLNNGALMLQSMRAYGPSRIWFEAALGQCERLAPPRPADSLPADFKVPDGAPPGRYTFHAAALLFQLSQALALERDHRGAVRAMRESYNTFKALLGPEDRNTRDAEEWLEKLTQSAVSVARQAKAEVAMLAQAGREGRIRRVQFATPGGAGGVAAAVGKEESGAKKGAGGGKLGMGAADTRKIEELVKYIEGADAGKTGKKAGTAATANPKRRGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVN9</accession>
    <name>A0A6A6NVN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="8">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_289192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="8"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVN9"/>
    <dbReference type="OrthoDB" id="2020662at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000036">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000003">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="4"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00052340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="714" mass="80695" checksum="C012C5E33E40135E" modified="2020-06-17" version="1">MHLFTVATCSLNQWALDFEGNCDRIIESIVKAKTAGASLRVGPELEVTGYGCLDHFLEGDLFLHSWEVLAKVIDHDDCQGIMLDLGAPIMHRNVRYNCRVIAYNRNRILLIRPKLWLANDGNYREMRYFTPWARPRHVEQYYLPRIIQDIVGCIKVPFGDAVISTRDTCLGAETCEELFTPDSPHNHMGLNGVEIFTNSSGSHHELRKLDTRMNLILEATRKGGGVYIYSNQKGCDGDRLYYDGCSMVICNGRILVQGSQFSLDDVEVLTATVDLEDVRSYRFTPSRGLQAVNSPAYERIEVDLSLSQPGSILSQEISPSSPQELRVHAPEEEIALGPACWLWDYLRRSKASGFLIPLSGGIDSCATSVIVFSMCRLAFDAIKNDNQQVISDTRRIAGESPDSTWLPSTPQELCGRLFHTCFMGTENSSAETRGRAKELAAEIGAYHTDMSVDIVVNSLTKLLQLVTGFVPRYKVHGGSDAENIALQNIQARVRMVTAYLFAQMLPTVRKRRGGGGLLVLGSANVDECLRGYLTKYDCSSADINPIGAISKTDLKRFIGWAETNFGLPILRRFLDAIPTAELVPLDPNTKEYVQSDEVEMGMTYDELSIFGRLRKVNKLGPFGMFEHLLHAWKDRCTPREVYEKVRRFYHYYSINRHKMTTITPGYHAEQYSPDDNRYDLRPFLYPVFTWPYKKIEDALRRHEEGAAQKEIKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVS9</accession>
    <name>A0A6A6NVS9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Galactose-proton symport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_68496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVS9"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053201">
        <property type="entry name" value="Flavunoidine_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350:SF19">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="21135" checksum="EB13B0BAB32B1D92" modified="2020-06-17" version="1">MTDSATMPPSSSTQDLDFTTLMRVERSPKAFGSRLVSLVSLPAGSRLCAMDAATPGRKAYSSVQVSRTQHVELNSDLVYCNHSCAPSLEFDTARREVRVARARDLRAGDPLTFFYPSSEWDMAQPFECNCGAGEGVCLGWVCGAKALDEEVLERYWLNAHIVEMLEERRKGREGMNREKGEAGTENSTEGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVU7</accession>
    <name>A0A6A6NVU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_349865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the GSE complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVU7"/>
    <dbReference type="OrthoDB" id="10020193at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11384">
        <property type="entry name" value="RagA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000488">
        <property type="entry name" value="Small monomeric GTPase (Gtr1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039397">
        <property type="entry name" value="RagA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF1">
        <property type="entry name" value="RAS-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="370" mass="41261" checksum="D8FCA2CF2F390163" modified="2020-06-17" version="1">MSTLNSSKRQKQRKVLLMGKSGAGKSSMRSIVFSNYVAKDVRRLGATIDVEHSNIKFMGNLMLNLWDCGGQDGFMENYLHHQREHVFGSVAVLIFVFDIESREFQADVINYANIVSALEECSPGAKIFCLIHKMDLVQTKLRQPLFEERAEYIRAASESFRDSVDFFPTSIWDQTLYKAWTQIIYFLIPNASTIETLLQQLAEVIDARELILYERTTCLMVTHVTRGIEAQNPFTDRFERISSILKTHKQSIAKHTGIPAGSANFAEMQIKTGRFMFFITRLTENTNLAASIPPSEQGFNAARINILLARQKFAELDIATKARPGIQEVFTRSAEADGTMGNETVTGSGLQAGKGKGAEYGAGLSGTMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVX8</accession>
    <name>A0A6A6NVX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_372999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVX8"/>
    <dbReference type="OrthoDB" id="3926513at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025653599" description="LysM domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="12870" checksum="9AB04A3F5AA05B24" modified="2020-06-17" version="1">MKSVASYLLFAAPFFVGQALASLNCTVADGAMVTEYACDVWFKLYNGMFSSGEDLVGCNYEGYPFEQTGLPFCYEESMMPSPTTCVGRAETPAETNPPITTLNAPPPGVGPVIPEAPPGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVY7</accession>
    <name>A0A6A6NVY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVY7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="25114" checksum="94CC23244B9024CC" modified="2020-06-17" version="1">MRHELFANNQLRATRSRARRLAGLPTFSVPTWAFSNSVMAKKGHQRRNPPSMASLGRVAWPLPVCAASRRRACRLSSCSPSLPAYLRRKARRYVGPHQLPLGSVSLRGKAADDTIGTNWGAGAVRWRAGPRRMPVSRSPREEVGFHVEGVSDRRRRAVGCAAEAISTVVVQRPRICLSAAHVRGAIDTDPWTCFLRFRFKCCKPPLARRPRASCHPGACNDCASTPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW73</accession>
    <name>A0A6A6NW73_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_71051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW73"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="19370" checksum="CCD2F67C1B9D56AF" modified="2020-06-17" version="1">MGKPASCKMQVDPAGHYNVDGPRVESTMKKENLETKFILIFLLTRHILLTNFPMRYGAFSRLVDSPLRELPLRSRPHSCRIGGLTGPSLLPGRISNERLTAIYCAGLRPASAAEGSRVQVQAPADLVVKQDRCQSELFRRGVKPSCGTHGRRRRPPHSGSTTRSSRPTVLGCRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWD7</accession>
    <name>A0A6A6NWD7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ubiquitin-60S ribosomal protein L40 fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_323160</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. eL40 is essential for translation of a subset of cellular transcripts, including stress response transcripts, such as DDR2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWD7"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000014">
        <property type="entry name" value="Ubiquitin-60S ribosomal L40 fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.50:FF:000001">
        <property type="entry name" value="ubiquitin-60S ribosomal protein L40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_eL40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="Ribosomal_eL40_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 12" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="14629" checksum="84AEBF89FA3EC797" modified="2020-06-17" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKMICRKCYARLPPRATNCRKRKCGHSNQLRQKKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWG6</accession>
    <name>A0A6A6NWG6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM4</name>
        <name evidence="11" type="ORF">BDY21DRAFT_347992</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWG6"/>
    <dbReference type="OrthoDB" id="747253at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097525">
        <property type="term" value="C:spliceosomal snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01723">
        <property type="entry name" value="LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034101">
        <property type="entry name" value="Lsm4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="7567" checksum="4015041F410DD228" modified="2020-06-17" version="1">MLVELKSGETLNGHLVASDTWMNLTLKEVVQTSPDGDRFWRLPEVYVRGNNVRAPPPPLSLPSCSSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWL1</accession>
    <name>A0A6A6NWL1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWL1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="21757" checksum="EC6B3EF27B1DFE9B" modified="2020-06-17" version="1">MGPTLSRRARGALALRATHLATLPAAKLNGSRATLAPPENRRPFTVPFSYSLGARNAYISASPFRHGGLPRVPRFDPLCRRGPPHQGAVRNSPKARCPPGPQPRHLPARAASPPALIHLKALPFPLFFTTRAFSCFSVAELSSWPIPSWDRSLTQTSRPRPASIPSISQPSLSLFSPELSLSSRPAPSPLFVAACDPGCRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWS2</accession>
    <name>A0A6A6NWS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_394697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWS2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="458" mass="49450" checksum="20D6CC30BE6FFFF6" modified="2020-06-17" version="1">MAQLSRLESEKQKHCPPRIGTCLRPNASGRVPNRVPVLPRLQGQARRFKGPARPKEAAAAVGSAGRRELGALAHALPNTPEDAPRRQTAPTPAVSRPGLLTSRKRARRERGVRRASRRLAGLPYGRSKYTFGPDVDSFRAVWVACSAKPAPGERQGKSPQGKGGLFAREKPRRRPPSERARRRLLPPAAAFCCCGAALWLPPRRRSTLLTHRTTPVPCPPGRPYSLDNGHAVGVYIGSSSVVLLCFPALFAFAFVSDKPWPGRRLLCDGQERRRRRRQLRPDKTRAGHEPPANPGPSAAVVPCACGRTRKDRAPATRRPAPSRVIVARPNYTHRRCLALSRSQAHPKPWDPGSRLPHARGAAVLAFFAAARHPRCPLSSSPPSSSFLRCTIRVSVAPPSRTGVAALRTPACTPLRFAAAGTAPGLPARHPPGSKPLQTLATITAKCTAQAARVDSAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX82</accession>
    <name>A0A6A6NX82_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exocyst complex component Sec5-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_372717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26242at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1406"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1480"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1551"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="87"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="186"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1075"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1313"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1085"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1114"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1146"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1165"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1581" mass="171713" checksum="DB83782502D1D06D" modified="2020-06-17" version="1">MADLERDLRNHYNLRTLTPERWPDEKDASSDDDGEVEYTNATASRRLSRRPKSRYSALERASSSRASIPNSQRTKDGIENLVQKDEPDPLGAAASVVQVLRSRGLPVEQDSKLRNRFLLSSTTFSPALFLSQVHSDASTESLLQGLDFLSRSIEKKSASLKVLVESNFERFVRAKATIDNVYTEMRSQGAEPAGDGQQRPGSAGRPQSRHANKSGGPGHFRSASSQQQLSPTGGGLQSEKRKNALTKESEYGVLGLKTPILEAAVKAEEVWGPALGGQEREEMLKAVLASVERNRDLFEIGPALRDAIKRRDYDALVEEHTRAHRCATDARFIVDNAVANRMPVTDPQIHQIIVTARMWSDVQEQIEQFKRFAWARLAGSQFPSHSRPGAPADEARSEEYMQLMGILLELGVEDNPIWYWLMTRYDFLKSKIQSTAERSRVEIEILRRRLANGDKPAPRTLAMHLRSVSGERPGETPRPTSNTMDTPQVLEFWEHVYLSLSALLSTSGGVLGEVIEFWDIAKSFIDGKAQRSLPMGIDGASARHHRLSADDIGLLVTEMANVFDMIRESVFGFFSDPPIDDISLLLSPAPGTPDTPRTPLSASINGLLSPTSAGPSADARFDPANMPPPSPSRGEPWEKYAFWPPHANALSGTHYLNRLLVLVGAAVGEMAASSVVREGGMRQDALRALVGGVRERCVQAVCAAWGADLEALCKASANGAAGGGLEDWERCLPERRDLTRMPARFAAFEAHLLGSVQRILFVSEAMSRNGASEVIVPPSAKLLQLVRSSFFGGLYKVIGGMVECAERGVARRGVGEGGARVVAGWNEEEDGLTVPLMGNGEAGARSGAGGLGYGPNRGRPSKNVRILLTLSNLQHMRADTVRNLISTFETNFSVKVSDEDKAARELLGQIDARLFQAYVAPIAERIAACVTAKITSAGWCPPDAPRPADASQYVYDILLDLVVVHTEVSTTAAPLTGPILKYLLERLTKAMKNALTQRPRYNLHALMQATLDVEFMAQTLGNYTTDGASQLQSDIYVRLDERTDAEARGRLQAELPHLRSILKGLRERTKGEFAMTAPDAGAGGANTTTTHGNTNTNGANGIDTIAATAPGATHLHPSSAHQQPQPPPQQQHDHQGPATTAPPPTSGGRPRSGTSTPGIPRSKSHSISSRLSSNAPPSTAATSRGWGMGGGDGGAADSRDRNRAVRTLPPWIRSVEDDEDELPAPPYPSHAAHHHYLPAPKPNAVPGRAYDHERERTPVTISSPMSENASKWQRFAHATTVRGLGGGIGLGTGYDDDVGSGGSGGFFMSGGGGVASAGTSPERRTTTDGPDGGVSVMPHSEVVDDNWLRQNMPDLEKPWQPEDLALLDRERSGGTGRHYWLFSPRGRRAKLKQWRRTLLRNPMVPLLVRLTVLMFSVLAMALAAAIFNKANQSGCSRGSSTWLALVVDAVAIAYTCCITWDEYTSKPLGLRSPRAKMRLIFLDLFFIVFDSANLSLAFEALTDERWACRSGIIADDAAPLPSENGEPISQAAIDNLTTCPFNHYICVRQKALTATLLIALLAWLVTFAISTLRVVERVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXK3</accession>
    <name>A0A6A6NXK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_349312</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXK3"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18833">
        <property type="entry name" value="GH43_PcXyl-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF17">
        <property type="entry name" value="BETA-XYLOSIDASE C-TERMINAL CONCANAVALIN A-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025386261" evidence="7">
        <location>
            <begin position="25"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="376" mass="41419" checksum="F57BE68B769DDE00" modified="2020-06-17" version="1">MMLPATFPVCSILLLSWLQSQATAAPYGGGQNTTFMNPILPGFYPDPSCIFVPELDDTFFCASSSFNAFPGIPIHASKDLRNWKLVSNALNRREQLPDLAITNGSTSGLWAPALRYHEGIFYVLTTLVHDKNPQEDPLRWENIIFKTADLYDPSAWTEAVHFDFVGYDPSPFWHEDGKVYVTGGHAWQVSPGIHQTTIDLDTGELGGPFVRIWNGTGGLAPEGPHIYHKDGWYYLMVAEGGTDVNHMETIARSKNVDGPFEPNPNNPIVTNANTSAYFQTVGHADLFQDAAGNWWGVALSTRSGPEYHTYPMGRETVLAPVSWKEGEWPVWANISGAMNGWSMPPTTLDLPGDGYAIQGARFCRDGPFLAGTTTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXQ5</accession>
    <name>A0A6A6NXQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_380151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXQ5"/>
    <dbReference type="OrthoDB" id="63935at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004074">
        <property type="term" value="F:biliverdin reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="29336" checksum="A39A12A7B052E112" modified="2020-06-17" version="1">MTSVKPIITFFGATGGCAANTLALALKSGHTCVALARTPSKLRTLMTEGHGVSDETLNAQLTIVEGNIRDVAAVKRALVHSNRLVDLIVSGVGSAPKPQKSLSQPITLHDPTICESAMASVTEALRALETDLAAPDVPVPKPSMVAISTTGVSARRRDVPLLFVPFYHWALAVPHADKARMEEAVVRAAAPPADGGVLAGFTIVRPSLLREGEARGVAAVRAGWELPAGVPDDAAPGSEPAPGPAVGYTITKADVGNWIFKELVDREKAGKWAGKCVSLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY52</accession>
    <name>A0A6A6NY52_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY52"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="11272" checksum="58E497D488CA6088" modified="2020-06-17" version="1">MLILSAIVAIVGSTFPRAPPRLAAAHARLVASPSGHLIKIPPPISDLPCFFAFNDPSCWFMLSQPLYSVKKENICPNMSYRWYCPFPLIYLSLLFSFFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYN8</accession>
    <name>A0A6A6NYN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_345813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYN8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="213" mass="23061" checksum="C9D9895C81030857" modified="2020-06-17" version="1">MTGHGRGGNRPPGGDRSRRGGQPAQGRSHGGHQAPPNPRGGGPSQPPRGTGTGGGNRPQHPNPPPVAPLGDQTNTPAGPSAPPAGQRSDIQRAAQIQAEKTMLDMYARENAQLRAQNTMLRSLAQDLRLQLEDTSIQFRMDMQSVKDAREQAADILKDVHETNPDSYWSKQLLKVLGGFDLSARILTREEIWAFMKVSIGWCFAGVRTNETLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYP5</accession>
    <name>A0A6A6NYP5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_346276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYP5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="17132" checksum="D5B966B5548F0052" modified="2020-06-17" version="1">MTGFAHRPRTAAARARTAAEPIRPTTARHPRTERAKLHDAARLPLTATAGVRAIARALRRYAASVIQTIVAGIGHRRVGGRRPRNSRPKKWSGRSRLCKRTRTSWRVVGESVLRSGRRKTRMKRSRADVACRERILPPACIARSLTLWRFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYQ7</accession>
    <name>A0A6A6NYQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_44598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYQ7"/>
    <dbReference type="OrthoDB" id="206700at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="104"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="467" mass="52701" checksum="C8949A4FDF24F8DD" modified="2020-06-17" version="1">MDQDPRSRSRDLTPSTATGDETPARSLASPPDEDKAARKTESPPTSVADGEKTARTPPQPASSGTSAPAPLTAAEEAKVEQILRACESQDLLSLIDYASTSGGFVNDEARRVAWPILLGCSGDPEIESPWQDLPVQQYERQIGLDVDRSFVYYPKHQTEKELAIRKGELSDLIVSVLRQNPFLHYFQGYHDIVQVFLLVLGPTASREPVTRLSLVRIRDFMQFTLAATKTHYKLLPDILFKADPELCRRVSDANPSCALAALLTLYAHAIREYSEVTRLFDFLLAHEASMSIYLFAAIILARREDILTMDPDEPDMIHVTVANLPQQPLELEQLIEHTMVLFKQHKPCTLPWLTWFQVSRYSVLKTTQDLQTRTSQCLGEARQQFTRHESELKFFEDVRKRYTFARLQLKKHRSSAKVAGLTAVVVVVAWWLAKSGSQPAFLRAFGGSMLLEPLRRISSFFRATRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYU4</accession>
    <name>A0A6A6NYU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HCNGP-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_321916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYU4"/>
    <dbReference type="OrthoDB" id="1714508at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012479">
        <property type="entry name" value="SAP30BP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464:SF0">
        <property type="entry name" value="SAP30-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07818">
        <property type="entry name" value="HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="32449" checksum="B77902A1B9F49515" modified="2020-06-17" version="1">MLGLSGYSSSEEEGSPPPQPTKQANAPPRVAEAADDKKEIAATSKPSEPSQPATTSHPSNGTAEGQNDTESMSKAQPPSATLAPPTSEPAASASPGAAATPASARDSSQSPYTAARDLTHQLTMPPVPNFAIPDSPPGSPPADATAKFDRFLALKRTGVHFNSKLANSAALRNPGLLTKLREFAGIGDDGGEEGNQYAQALPQGLGVRVEWPEWAFADRLEAAQAGVRKKREGEARAKGREGVEFVAAGQDVPGGSGKKSKGARESVPERLRKGVDEGRQKSLPKEAERRGGESGRKRARSRSRSPRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ57</accession>
    <name>A0A6A6NZ57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_344695</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ57"/>
    <dbReference type="OrthoDB" id="19102at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="220"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="262" mass="29480" checksum="1E1A87914BC533D6" modified="2020-06-17" version="1">MDVYYTLPPVSRTITAAALIASVGVHAGFIPFYYVAFIPQLLWKIPPDIWRPFSSFLITGAGWGLIFDLYFLYKYSSALETESPRFSRPGDFPTYIAFCWVVILATAGYFMNGIIFMSALELAFAYTYSQDNPYRKTTFYIVTIQTRFLPYVLLLMTLVMGGQYAAMRQATGLIAAHLYDFLTRIWPTYGGGRNYIQTPEFVARMFGSQARSQRNRGYGVAYAPGNRAREDTPAGRTTGWTSNFGMGSSWGRRGPGRRLGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ81</accession>
    <name>A0A6A6NZ81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_372348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ81"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="18055" checksum="16464985FE8C4AA7" modified="2020-06-17" version="1">MDSLDSTSCPEYGTPNSNHDSFLIINGSSDTSSTDSSTAPLIHTPESTIDQNLFSDFDGVHFHESGILDQTEDPEVEHEVVGAVEPSDASSQVPRDMSLRELAFLARKARRRAEKPRNRFWEWLKWLFEKLMTPLRRMTLKSQDTGILEEYGCTNPYIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZX2</accession>
    <name>A0A6A6NZX2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme/RWD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_364170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZX2"/>
    <dbReference type="OrthoDB" id="9993688at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015368">
        <property type="entry name" value="UBA_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09288">
        <property type="entry name" value="UBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="274" mass="30280" checksum="ABCEE2BF2AB1F435" modified="2020-06-17" version="1">MASNRSRRIAKEIKDIQADTHSKITVEPLDGADDLTHLRGMFWGPPDTPYEGGKFFVDIRIPSEYPFRPPVMKFETRIWHPNRLLFPSSPSTIPWERDAKFSAPSLPGAAGHTQGAICLDTLSTAWSPVLTIKSALISLQSLLSTPEPKDPQDAEVAGMLIRNPAEFEHVAREWAVKHAGAPPRRERGEGSGGATAESIKKKEKAAREGEERAKLAAYHGYNKDLIDRFVAMGFDVPAVVAAFEYVGIDKMNGEDYELEEAYMGDITARLFGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0E6</accession>
    <name>A0A6A6P0E6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_345425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0E6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7192" checksum="6C915244F8A83944" modified="2020-06-17" version="1">MCDTTTLMHLGNGLFLSSTRPSGIKIPSSARPSRASVTVSLDSESSGLEMVRCREVRLCTSSNELAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Y3</accession>
    <name>A0A6A6P0Y3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL11 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_344345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Y3"/>
    <dbReference type="OrthoDB" id="1091498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6110" checksum="419A069B233AA823" modified="2020-06-17" version="1">MARKALAKNVLVKMIVGAGQASPSPPVGPALGSKGVKSMDFCKVSQKNDLPPSRPPTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1A0</accession>
    <name>A0A6A6P1A0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_285752</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1A0"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000142">
        <property type="entry name" value="Similar to FCP1-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="156"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="515"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="338"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="657"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="792"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="815"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="842" mass="92516" checksum="567F22F27AEFABC8" modified="2020-06-17" version="1">MLLRSPKNLHYPVTVTELLKQHNADVDKYAPLFSYFYKSTVTTGNDFGEWVEVEKTFPTVFESETDGKIVSWKIDAGAVISGPGIALVEIEEPCRHEVQYGGMCADCGKDMTMVSYNTSSRDSDRATINMAHGTTALFISQSEAARLEEEAKRRLLSKRKLSLVVDLDQTIIHATVDPTVAEWQKDENNPNHGAVKDVRSFQLVDDGPGGHGCWYYIKLRPGLMQFLRHISELYELHIYTMGTRAYATNIAKIIDPDQKIFGDRILSRDESGSMQVKNLQRLFPVDTKMVAIIDDRGDVWSWSDNLIKVNPYDFFVGIGDINSSFLPKRQEATAKEASQVRNKALAPGPAVKKQSGQDENGSVAQAPKSTNGALSRIGEQLVAMGGGGDPNVLQSQSTQQEAAIAAQVSDRPLLQKQKQLDEADEKASEESTNSDSDSEQPSQRHNLLHDDDNELDFLEQHLRSVHRAFYEEYDRKLHGSHGGRVAELRGERPARKLPVDDLRIVPDIKAIMPFIKAQVLRGVNIVFTGVVPLGVDVYSADISRWAKSFGANVSDHISGKTTHVIAARDRKTAKVRQAAKRPHIKIVTMSWLLSCFLQWEHVDEGPHIIHAEPDETNLHGSTKALSPFDEPEDGTKLSSSDDEAAVTDYEDGEAGLTIATDVNDDIPDSLLPTSPTDESRQLNAAEWEGIGEELKEFLGDSDTDSDSDASEASNSTRSGSVTPKNRKRKRETQSAESSETEESDSSAKSQLGSRLQKRKRRALERVSSLTNVASADMSSGLPSPDTTGPEGGQEEEDEEDGGEVKKAAAGNSGEADGDEDDDDMAAALEAEMEAALDDDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1L3</accession>
    <name>A0A6A6P1L3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_15157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1L3"/>
    <dbReference type="OrthoDB" id="3210378at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="64124" checksum="AC2F5FD474D641DD" modified="2020-06-17" version="1">MEPRTASLPSYTSLPATPTQKYSRQNLPREVHECILNQLEMAYFGSGEESCWNCYLKDLRNFSLTCRSWDRPATAQLYRILCVPIGDDLFQPAKLFRPRTASRLKLLRRTLRERPSIARLVQVIIVPGLQDFLDGRNEKEQGEVMDSLASIVMACPRLERLTGYIPIYRHQFDRLTPSTPKRPLTPRRRIKQSDVESPLDQATSFLQFHQHWSLLETLFISGQSMGRLNSEMFSYTLRGLPSLRHLFLSNFDAEDFHDKSLLSLPALHSLRLESLPGLTDRGLLHLASSDSATQLRRLSLIGLEITFLLVVSRFVSALPHLRRFTLVQDASPGLMPGAVMAKPVFRSPSLEYMHWDVLVPGTATDEMVESIRLGALPNLRVVRAPSDHDGRIQDMCRPAAAIETRGAAATVSSTVVDQTLRDGRQPLRLIDMLDSLPVVTSDTHYLRTLPAARLAAQHRIQAARRKRATKIVVEDQDGVVSRVHKLRGFVGTVGSRLEYCLEPDVEGSEDAVVGLEDLIRGRPAKEEKLDGKAFCTGQRVITEAGLDRMWSHAPRQKYLRMELERFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1S4</accession>
    <name>A0A6A6P1S4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7871 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1S4"/>
    <dbReference type="OrthoDB" id="4140664at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057193">
        <property type="entry name" value="DUF7871"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620:SF1">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25277">
        <property type="entry name" value="DUF7871"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7871" evidence="1">
        <location>
            <begin position="8"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="111" mass="11122" checksum="C8FE446EB02E4FD1" modified="2020-06-17" version="1">MTDPTPSVPASCCGRSGEGCVCAKEATCSCGKMPAMQCNCEKAATENVVSGARCSCNQRAAGHCTCGRAAEENAGVAGSTCACGKRSSDSCTCGGTEPAAHAEEIDFTTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1U5</accession>
    <name>A0A6A6P1U5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_20407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1U5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="71" mass="8332" checksum="9FF2EF82A610327E" modified="2020-06-17" version="1">MYEERALFSTCLQRSIFSIFLALIFEALISTPLLCAPYQPRGSIIGYESHTRIITCLCRKESLFRYSRRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Y8</accession>
    <name>A0A6A6P1Y8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_284788</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Y8"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="476"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="654"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="681"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="834"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="873"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="915"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2457844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="974" mass="107270" checksum="CDE77DDCF3E58647" modified="2020-06-17" version="1">MSRAPLLLRSSPAQGTGSYGVLPTLSTSSSSSEAGPADANEPQPARTRKGKGKGLLRHSEPVGDRSGLTFGSRSDTTSREQGLDSGARISRRSAARSAHGRSEGHFGEPGADRDRSSDGFKAGKGEDTPSSSAAAQTSSSSGDDDGEDEDGTPDHAVGDKGHSEDPPDNSPYAEVRAAVSPTDDTTLSINTPRMWTLSILFAVLGSSTNLFFSLRYPSVSITPVIALLLVHPLGLLWDQLLKGNNDPDETFVNGTLVCQSDLSGDTQPFQQVPSHDGSIISAAQSRSLHARGSWKRRLRIWLAQGRWNEKEHCCVYISSNVSFGFAFATDVIVEQSMFYHQKLGVSYQILLTISTQVLGYAIAGLTRRFLVRPSGMIWPVTLMSTSMFATLHKEDNKPANGWTISRPKFFLSVFGGSVVFYFLPGLLMPALSYFSVITWFAPKNVVVANLFGIASGLGLFPLTFDWAQIAYIGSPLVVPFWAAMNIIGGLVLVMWIMAPIMYYANVMYSSYMPILSSAVFDNTGKPYDVSKILTKDFVFDKVAYNNYSRVFLPITYVLSYALQFAALAALITHTACWHGRDIWRQWCRSLREIQSDGKGSYQPLPFANGDGSRSSTIISRTSDRMNSSEPTLDNLMGAEDVHNRLMRRYDDVPISWYLATGVVMTAIGIFIVEYFPIHLPWYGLLLALGICTTLFIPIGIVMAITNQQSSLYLICQLICGVVFPGRPVANMVFTTYGYITSTQGLKFSSDLKLGHYMKIPPKILFTLQTSATIVSSLTQIGVLNWMLARIPGICTPSAINGFTCPLARVHFNGSILWGVVGPARFFGPGALYRPLVWAFLLGAIAPIIIWSLGRNNKRSFWRKVNLPVLFGSLSWIPPATGLNFSVWALVCWIFNDIIRKRRPEWWGKYNMTLSAALDSGLAMGVVVIFFAVLYPGWMQGFKWWGTEVYKQGCDWKACSYRTLEPGEHFGPEVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P201</accession>
    <name>A0A6A6P201_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_284832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P201"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF466">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="118"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="171"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="263"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="301"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="353" mass="37203" checksum="D9D3488FE894E54B" modified="2020-06-17" version="1">MALFAFGSNGSGQLGIGHEEDVNVPTSICIGNDTQELDLPAHIAAGGNHTLVLCSNGDVYASGNNADGRCLVGAASATKHRLARFEKLFAETAPYELFGSFKGCAATWEASIFLTNGFKLLTCGTGEKGELGLGSTCQTTDPRPVEIKEPSEDIIQVDAGMRHVVAVLSNGDAYGWGAGRKGQIGEPNQDCFIPRKITGIPFKVQRAVCGSESTVLVGPPETGELLIIGSDKHSVRSNAPNKIPGWKQVVASWGGVYVLSDAGELVGWGRNDHGQLPPPDLPRLDMIAAGSEHMLVKTEDGKVLAWGWGEHGNCGVPVDDQGDVKGKWNEIPTNGNVISVAAGCATSWICQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K7</accession>
    <name>A0A6A6P2K7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_343363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2K7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025613949" description="Anaphase-promoting complex subunit 4 WD40 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="22762" checksum="7FC7BED8A58D5E49" modified="2020-06-17" version="1">MALRSLAGLPLMRRVLAVRLRDRAGCPTCCRAAAAGLGPTWVGCGDDEEYVMWPAPAPTAGVAGRELEDEWSLEERAWLFAMPRPPWVCVVTYSADGAVVVAAWDEPSALAGVEQARACQPTRPFPPGRGADLGQPRPRRRAGGCAAPALAKRLRRTAAELKAETHRLAPTLPPSSPCSARSRAPCCIWPTRASTARRRTSCSTRTRPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2V3</accession>
    <name>A0A6A6P2V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative peroxisomal membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_342225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2V3"/>
    <dbReference type="OrthoDB" id="195498at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="4"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="6">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="169" mass="17903" checksum="AB204B2EA3880EAD" modified="2020-06-17" version="1">MAPLKVGDKFPSGIEFAYAPITDPSPTACGMMTTFSCDTEFANKRVVLVSVPGAFTPTCQANHLPPYLSSASALAAKGVDLICVIATNDAWVMAAWGKANGVPPESESNVRMLSDSKSEFGKRFGWSLGERNNRFAMVVEKDGTVSYAECEEKPGVVTVSGAEAVMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P333</accession>
    <name>A0A6A6P333_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Dicer-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_319388</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18802">
        <property type="entry name" value="SF2_C_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000032">
        <property type="entry name" value="Dicer-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="32"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="383"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="19">
        <location>
            <begin position="572"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="16">
        <location>
            <begin position="933"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="16">
        <location>
            <begin position="1116"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2458152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1420" mass="159849" checksum="B154B3BF6B5BFF81" modified="2020-06-17" version="1">MARSAACSSVAELAEPTETEDDIQLRDYQTEMVEAAMCENIIVAMDTGSGKTHIALARAEAELESGQRDKTIWFMAPTVALCNQQYNMFRRHLPAYQCRFLSGNDGVDSWSDQMIWDAVLLDIRIVVCTPQVLFDALSHGFVQMAGISLLVFDEAHHCTLDHPANQILKHFYHPLLRMDPGSAPRILGLSASPVMKSKVSGLETLERNMNAIAKTPKLHRTELMKYVHRPVLEKAFYKGGLTTPFSKCLTILQNKVETLQLEDDPYVRSLLARLKANPHDIVTRNSCHKVLINERTYCRDQLRLIITRSEAIEAELGEWASRWYIKNVLSMRLGFIQEAAPRFIQFSNEEKTYLHGVLSEIEDSIRDELAVGDFETSEKAAQLIELLCSEYRAQFTGIVFVEQRATAVALSNLLAAHPKTRESFRPAPYVGLSASNKMADLIDPRGLDLTLDEFTAGKKNLIVSTSVLEEGIDIPNCHLVVCFEQPKNLKSFIQRRGRARKQDSKYIIMVPDTNPIKGPEKWDELEQVMKTMYLDDLRQAKAAKALERIEEDVGRIKYRVESSGALLTLNNANAHLYHFCNKLLSGSDIGLRPQFAFTKEPLSKLKSATVTLPSSVNPAVRTASSSLAWKTERNAAKDAAFQAYVALHKAGLVNDNLLPLTQDIEDALRSDTIQDGPSLVLTQSTLDPWHSIASAHRSDSIIWSKTMISLSMGEFGSTAVMMFLPLAVNCIEEIPLFWNETTSFTASTKYVGDCHLSQEEVSVIRKSTLILLSTVFGTRVDETRTEYLVYFAPEFRALHELHHWNQTMIGRIPAKDAMLPSLMPGQTNLLKIGRESIQLTKPFIVHNFSTTIIEADDDETHEELILHISNFPKKRDFFRPWTMATEEIRNSAYTSLRTIPAEACQIDNISLQHSLFVLFVPSILRRLETWWIADELVSTILAPLSGMSKRLVLTAITASSAYELDDYQRLEFLGDCVLKYCTSMQLMAQHPLWPEKYLTEVKSRIVSNGSLARAALRTGLDAFIIAETFRTAKWKPKTVDDVLGETGRSAEQVPRSRKLLADVVESLIGASFVDGGLDKALQCINIFLPDQMPSRTLKEAHTTLYNNANQKDDVQLPDLEALVGHKFRNPALLVEAVTHGSFKGYGSDAVVSYQRLEFLGDAVLDLLVTRSLFAHQPPLSHHKMHTLRSANVSEYLLSFVVMEHCMLETRYEIVTEQSGNGKKFLPHEKQAKRAIWQFMRHSSVDVADHQQRVVARHEALREQVNSALWTADEFPWHSMVQIGADKFFSDLVESVLGAIYVDSLGDLSACSDFVESLNIMDIMKRLLADNVDCTHPKEMLGQLAVTDTVKYYIREEDSNPNASPEQQRPRRFFGVKVGESFASEIPDGDWTAGLRRLDIETCVASEAIKRLRADRMDKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4I6</accession>
    <name>A0A6A6P4I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4I6"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="12124" checksum="D7CF1A665607BE7F" modified="2020-06-17" version="1">MDTDLIARLYPADGRGDGALAFYAIEQVAENRSRPGISFHHCALTFEEDFDDCRQYRPVLRDLGSTYGTAVTYDDNKRHRRRNFRWILGGHEVLNGIEQIVIEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4N6</accession>
    <name>A0A6A6P4N6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_362468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4N6"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="42433" checksum="5C981F44FCCF5D92" modified="2020-06-17" version="1">MGALVSLPLLSYLALPALSSWSTSLNILFFYVTWSTLLWTYHAFSITFLLLLSVRLLVSFIPSLLLLLLDAAVPSLAAGLKAAGPKALATRQMAPAQLARMAGLVLFNTLFGITLLSIAADPGVLSRCIIDPVRAELLYLGVLKPSLKARYGGLALAPTPPLFRPLVRVSAALPSPYNLLLEVARGAALRHVLQYAVHRRVLHDAGWSRWAAALARRHARWAHPAELSHAFALASAADHPLCHALHRWLPLLLPAALARAHVLALALNVALAAAEETAAWCGFRYVPGFVLPGVGVAQRRVEAHVESRGGCCFGTWGVLDWACGTGPSVVEDVVGGRGGAEGEGDDGGAVAAAGKKGRRAEGRRSAGEEGNGGWKGMVEGTVEDGMDKTGRKKGRGKTKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4R7</accession>
    <name>A0A6A6P4R7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine kinase 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_211774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4R7"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF149">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="580" mass="64347" checksum="D2EA9D453B5CE7FD" modified="2020-06-17" version="1">MEMNYDDKELHQIEEELHVEILPGTEVMADIGTHHFVKAEGHGNRVLVPQPSDDPHDPLNWSIGWKAACITASTWTTFTQGFGPLALAPMFPYYIEEFNCTLEEAVQFTGVCILVLGFSNFIWVPLSSSFGRRFVYITSQVVNLGSMIWRAEAHSYGSFMGACVLNGIAAGPAESIQPAVIADIFFLHDRGKWNTLYWTAYMGSLMVAPIISGPMADTVGWRAFWWLNVAMIALSIAMNATMFPETKWHRKHPKEIIREAREAQEAAKASGNDSSAKPTDEKLERAPSSSSQSKREDINGIAQVPTAMSRIAAQEGLTKVPTADQDPWLGRGSPKKSQWNLIQPNKNPFKSILLDLFIPWKLFLFPIVEFSAFVVSWACSTFLQINLTQSQAFEAPPYNFSAQSIGFMNFAILVGALIGLATAGPLSDWVSARATRRNRGIREPEMRLPAMIPYVIIMFVGAIINCVGYDNHWPWEAIVIVGFTTCGITVASLPAIATTYAIDSYKPVAGSLMVAITVNKNVWGYGLSKFITEWAISDGFVAPIMTNSALCLVFCLFGILFYYKGKTIRRWSKNSSVHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4W8</accession>
    <name>A0A6A6P4W8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable kinetochore protein NUF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_199763</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NUF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4W8"/>
    <dbReference type="OrthoDB" id="8194677at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051383">
        <property type="term" value="P:kinetochore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045132">
        <property type="term" value="P:meiotic chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.60">
        <property type="entry name" value="Ncd80 complex, Nuf2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005549">
        <property type="entry name" value="Kinetochore_Nuf2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041112">
        <property type="entry name" value="Nuf2_DHR10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038275">
        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18595">
        <property type="entry name" value="Nuf2_DHR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="16">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Nuf2 DHR10-like" evidence="17">
        <location>
            <begin position="280"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="172"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="312"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2459045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="460" mass="53212" checksum="8FE091E5152425E4" modified="2020-06-17" version="1">MDFNPRMSTARASANQRSRKEEQEDAFMTLSEKEIAGCISDIGIPFSVENIQKPNPQLVQKVFEWFAELLMNTSREVVAPAMKAAAEDLCGPEADRVFTPDTRDLAAFFVMMRKLLLECGVNDFTFADLYRPTRERLVKIFSYVINFIRFRESQTAAIDEHFNKSERTKMRIEQLYHDNQGAEATLAELERNRDATDQVLRDKQRRNQELRERLLELDKGQERVGEKLKRAKEEQQRLRGLLEERKAATAAVRQDAAKLRPYTQASPQALEATLRDLNVSLAADRATIDSLDRRARALGTSSDTFAVVSTDVTACTRLLHELQADLAKEEEELAKAARHRDALSDRSNNVRDVERQERLLQKQLSNVNARTDKLRRGAEEKAEQARLRMEELKTVHKKLAEERGEKGRDMERRRVRIEQTEKKMADLKENIENEVHSAHEEWVKMDSHIRLYITEMEQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P519</accession>
    <name>A0A6A6P519_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_370579</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="12">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="12"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P519"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit Rieske, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.270">
        <property type="entry name" value="Ubiquinol cytochrome reductase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037008">
        <property type="entry name" value="bc1_Rieske_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="15">
        <location>
            <begin position="164"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00072517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2459096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="234" mass="25189" checksum="1A6ED855C8CC94BE" modified="2020-06-17" version="1">MTAALTTSAGALVRRCARQQLPAVRAAAATAIQQRSGSSTATFDSPFKGSGATKVPSFSKYKSSSGETPNKMVQYFMAGTLGAISAMGAKATVQDFLVNMSASADVLAQAKVEIDLNSIPEGKNVIIKWRGKPVFIRHRTQDEIQEAENTKWESLRDPQPDSDRVQKPEWLIMLGVCTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRARKGPAPLNLEVPEYSFPTEETVIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5S8</accession>
    <name>A0A6A6P5S8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_189229</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5S8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025615301" evidence="4">
        <location>
            <begin position="17"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="311" mass="33435" checksum="80CDB66358F8F7EF" modified="2020-06-17" version="1">MLLVLGLLFFVGGIRQNKTIVSPDSITTSIHVISIAILLLSVLLRPLASPSTTEPSSSPTKCLTLSLTTSVFLLVLFATYIFLRLRAPTSPPKSLEDISDHIERCGPQGGSPTSRPRIPSASTFTTLSPTPTLLPSQSFSSISRLQPILTALLFATSSFLFTLCAYTLFSIVTDPTSSHILPHRFTTAVLLPLLAQPLRIFHGLYTVLHDHSLEIATATVATSNVTLALFDLPILSLAGWIFKHNDVLVPSHGRKAGLADDVYDGAVLLVAVVVAGFVVKKGWSSWLDGALFLGLYGMIGLGFWVRVSESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P674</accession>
    <name>A0A6A6P674_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">HAUS augmin-like complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_191535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P674"/>
    <dbReference type="OrthoDB" id="5372507at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026243">
        <property type="entry name" value="HAUS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25762">
        <property type="entry name" value="HAUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="241"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33505" checksum="FB15AE971A13AC21" modified="2020-06-17" version="1">MDDSGLDPSAFFSPSKARQQRAQAQDWQQVDSWLAKIYHGRTIPSFERNEDTLKALLALATANERADEEAELVEELQQEALKEIENDSSNPDVEVYDTITDALTPEAHGNLDALSRAAVVLDVPRAHPESIASALIPHTHTQSTLSIHLATLQHLASTLETTLETLHAHLSALQSSAFAPPSALANQTVDWTRKTKALRAKLREYEDRLATLSPDYRGPASPSKGGGKRGSKQPTVTIGGLVEREAEVKGLIERVGDLERRVGAFKGLPDRKEEARKEVEKARRRLEELRAERDRLFEELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6D3</accession>
    <name>A0A6A6P6D3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6D3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="18680" checksum="E13D0509D7B9A74E" modified="2020-06-17" version="1">MADKTHGIALSPTKPSYPRSRQFNPSRARARRGGSQRTGRPSSTKPPRAFLGRSGSTPATPSHPRRAVRTYRARSARRAARSYAVPRWGEAGRSRHAASGAVEPGEAPRGAPRGRGAGAAPWVVEDRRACRAVEAGARWRASAVVWFVGGRLGSEMAAKSGSRWMRREEGVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6H1</accession>
    <name>A0A6A6P6H1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vps41 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_190069</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="244107at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="175"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="387"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="3">
        <location>
            <begin position="930"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1171"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1288" mass="141117" checksum="E0B247D6600D4E97" modified="2020-06-17" version="1">MAGPAADTSTPQRLPAGANGSTDAGAPRHQSTGNAEHETDDDDEEEEDDEDDEPRLKYESLTGSLNSVYRNGDATSAFLVAADKMIIGTHNGRINVLALPNFQTVRLYHAHSASVTAVSVSPFPPPWPTTKSDIANRLGPEATVSPSRASTNNPPAPTSPRTPRQNQVQIPATPSNSIHIATSSIDGHVCIQSLTDTRDVMLRNFARPVQAVALSPEYRSDKSYLSGGLAGELILTVGGRSGVSTNANTSSAAAVASGWLGSIGLGSNNGRDSILHSGEGAISIIKWSLSSKYVAWVNEQGIKIMRSNVKLESGESDLAWKRIAHVDRPNRRGWEDMAAVWKARIDWIDDQNLESDSNDSPPENSHQIVERLKNAAQSDRNSIKSGPSKKPQKVERLVVGWGDTTWIIHVKHGGPGVGKDVGEPSAGTADIVHILRFGDCIISGLSLYTPSLLLVLAYRTRDDDDRPIGQSPQTTPRRGVQHRQDGLPPELRLVDIASKDELDFRALSVSRFESLSAADYHLSTLYVPILGPTGPAQKGALEVIGGGLWDAGVSAGRILSSGASILSLANSADNGKASIVSPSSSSIGKPSMLKPRERDTHPALATAGLKIFIHSPYDCVLAVKRDLADHLNWLLEHEDYKQAWELINEHPEAVTNVPERNLADSPTTTPSKTQPTLAEFFADDSASQTTASATRMYNSAIEKEKRRIGDLWVQQLVTAGDWETAGKVAGKVLGTSSRWEHWVWTFAEVGRFDEITPYIPSTQLKPPLPSLLYEVVLGHYIVKDRVRLKELVKQWDTDLFEITPVIKAIEAKLGSGDVTEVTVEDGEQGRDWRILQEILAKLLLADGKPREALKCYIRLQNADAAMDIIRDYNLLHAIADDIPGFILLRVSKDLMESGSMPELEEASSDAIHLLVDEAFQGVVRPDVVVAQLEQKGLDYQPFLFFYLRELWNGKGIQKEYGHGSQKIESEGRSIVEEFADLAVELFAEYDRQLLMNFLKASQSYTFETACQICERRQYIPELVYLLSKTGQTKRALHLITATLGDVSLAISFAKEQDDPDLWDDLLDYSMDKPRFIRGLLEEVGTAINPLMLVRRIPEGLEIEGLRDGIHRMLREYEIQYSISEGVAKVLRGEVAEGMAKSREGRLRAVKFEVVHQQPGEVEVFAEPVDGAVSSKERAPEEEEVEKEESASPEVEPGYCVGCRYAFAEDEKETLVGFACGHVFHLSCLLHAVGTSDEAAEDLQMRLASFGEAEGSYTRSVGAKVAHAHIIRNAIKGGCPECLKTEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6U7</accession>
    <name>A0A6A6P6U7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6U7"/>
    <dbReference type="OrthoDB" id="3938057at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="239" mass="25375" checksum="FF6ECCD90D80FFE1" modified="2020-06-17" version="1">MDNASYAPSPQKGTEDNVAPIPKGKITSTFTPDTVAVLVMAIRKNNRSLVGLYKLMAELDPGKRTQSGFEHQFRPIVKRADELSTMVENGTLSVDGNKKTAAASNKRKAGESPAADGSHADYEGNNDAPPKKGRSSGRKKQATGSSGATKKRSTNKGGEYPLPPPRTVDFANVFNPAVAPPPQFSSHPNFGMHNAHFGGNPHGFAAAQNANTVVQTESQNPADPNGRQVNTIPEFGELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6V6</accession>
    <name>A0A6A6P6V6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Receptor-activated Ca2+-permeable cation channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_282505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6V6"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="290"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="700" mass="79713" checksum="B124037CCB53E832" modified="2020-06-17" version="1">MERTETNRSLHDALRVARSREAQERFLAGDDDEEQQADGADEAADEHVPLASNNFNNHADLPVYTTIHRIRRLVRASIDDPYTPEQLKEPRMNVLIVKPLVDRFFDPDDISVVYCLLVNRVQFLREQSYQAHHQTVNSSRAALCEILAIKILRRFDEENSGREGLLLLANILIAGFEPFQNAPEEVVRDSKHMMQWSIQKRSSSERTCCALEIGIISESKAFLAGTACQKVVDAVYRGRIVYTPTSFIDILPDHYKRKPICLYDPRKAPLLNQYRLIVPRIRSIIEVCQFFVLLVLYFLAMTHRNHLVLTGYEVAFIVYAAGWVLDEFASMLEHGWHVHTQNLWSFLDVAFVAIYLAYVIVRVHGFVTDDVRHGRTALDLLSIAAPVLLPRLAFNLMPENMLFVSLRAMMGDFTSLTALAVWCFAGFLLAMKWLTYPKVPAGEPAPEMPDAVTISKWMLWIWFGLDGTGIQRSPEFDLVLGPALMVAFAFLGNTLFLTILVSILSNTFAKIVADATAEIQFRRAVLTFEGVKSDAIFAYRPPFNILAMVVLLPLKFVLSPRWFHKINVVCVRTLNAPLLLIISLYERSHLWRTTKRKLHASGPGARRSWLSSWNWSQFSVHGDVQAVFEVDPPQAIIDEIEEVDIVDEEDNILSNGFMQPPRTFTGDRSLSPRADGRSLNPRRRRMSSATRVFPSRPSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P712</accession>
    <name>A0A6A6P712_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_377890</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P712"/>
    <dbReference type="OrthoDB" id="446044at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF1">
        <property type="entry name" value="MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="8"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="117"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="214"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="336" mass="36377" checksum="32B02D3FC6A0F43B" modified="2020-06-17" version="1">MAVQSKELPPWGYAVAGATGAVIANALVYPLDIVKTRLQVQVKRDPGATDTNPADGQHYTSALDAIGKIVKDDGVPGLYAGMAGSLIGVASTNFAYFYWYTVVRGLYLTSRQLSKPPSTAVELSLGAVAGALAQLFTIPVSVVTTRQQTQPRGERKGLFDTGREVVNSEDGVSGLWRGLKASLVLVVNPAITYGAYQRLREILFSGKQNLRPWEAFLLGSLSKMLATVATQPLIVAKVGLQSKPPPAREGKPFKTFGEVMLYIIEREGVLGLFKGIGPQITKGLLVQGFLMMTKERMELLFVVLFSYLRKIRTEKLQKVADMAADKAKSVAPITTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7D8</accession>
    <name>A0A6A6P7D8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_275599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7D8"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="50030" checksum="099BE11892D8598D" modified="2020-06-17" version="1" fragment="single">GQLQVPRTTIQRPHSAVTPGSDFGPRGRAHSPQVSIGGSPTSSGSPRSYGRALSSSRKSPESRPTSYVDLLNNIPYHQQVAPTSMMALDNADLRSVVGSNASLLESKKTLEMYRANVKKTNDPAIQYEFAIFMVHAAQDLNAMPPSPATTEQYNDLIREARTILQKLSDRGYPFAQYYLADGYASGLFNKGKEDWDRAFPLFVAASKHGHAESGYRAGLCYEFGWGCRKDYAKAVQFYRQAASKNHPGAATRLGKACLTGDMGLGGRHREGIKWLKRAAEGADYQYKEAPFELALLHLNGYRDDVFKDEAYAAQLLTQAADLGHVQASFLLGEAYEHGRLGCPRDPALSVHFYNGAAQAGMPDAMMALCAWYMVGAEPVLEKDENEAYEWAKRAAELGLPKAEYAVGYFTEMGIGCRRDVLEANRWYVQAADHGDDRAKQRLAIIRAAASGDPGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7T7</accession>
    <name>A0A6A6P7T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_275634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7T7"/>
    <dbReference type="OrthoDB" id="20669at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF12">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="255"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="379" mass="40985" checksum="5EC64817EB3B737D" modified="2020-06-17" version="1" fragment="single">PAVIRRDMLQGDHYDIQGIDWASLGTTREEARLMRGDTFAQISVTGAEIEAPKESQKALASTENFYRFSRMNTSCNAYIRHYQLRNLLVATSNSDLYYADNKRVYHAHPCGMDKETVMDFSRDTTDPMEVTALSGCDNFLIAGGYNGHYAVKNLLTEVGQKPTVGKLTTDDNGITNHCHTFYDRLSGQMKAAFCSNDRKLRILDCETNKFTAALPYHDPINCAATSPSGRLRAVVGDFNQTLITDATSGATVVTLDTHSKDVFAAAWAPDDITVATGAQDSHVVVHDGRMWARPLAVLGTPLSCPRSLAFTPAGSGPRALLAAEADDNVHAIEAGGFAAQQTLSFFGSVAGLAVPPAGDGFFVACSDPHFGGVLEYERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Y5</accession>
    <name>A0A6A6P7Y5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_282127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Y5"/>
    <dbReference type="OrthoDB" id="5331396at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849:SF1">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="97" mass="10649" checksum="A658604DFE3A3C91" modified="2020-06-17" version="1">MGVRASVQARGFRSSQRLMDSAAPVKKPVGAFRGGLVGFLLGSVMAGAGMYYYVIDEYKVSNELLTEDIFTLQAAVQRIENYVKTLEDKIAEIGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P835</accession>
    <name>A0A6A6P835_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_338696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P835"/>
    <dbReference type="OrthoDB" id="3596604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="585" mass="63996" checksum="817201EFE05E1999" modified="2020-06-17" version="1">MSSSRDLSQETLTSDSIPSGGSDSRTENISYAPITQQRTPTFGPDPEKEKALFAHARVRTDDSLLGSYSRDPNQGLDEALNIARPNRSSREFAKRNLKRLLRSGLARCVLSWCLITGFHILSWQYRDQVISPSMKSRFDVITVALSIAFGLNIAAGLRENALSLRWWIVSFRKRPPQTVDLILHCDDFLNIMKLVVVAKERTLVFSCLFWLLLNVLVQVGIAVLGLTFEAVPGVGDIFLRPGQNDVSIPNMESFARPSYFSEEQSVQSYSAHVLGDVGSSFNFSALPDEPLEGKPWASNPASFWKGNDYWEYVFLDSAPFEGSANPRAVSVYSNRVVRSSAKCVVPPFNATLEGDLEVIHAEGSDRNVSFPSIATLSQSIYYLTRPVLSTDGSESGNGTCGPGCSSVQIFEPRAGPAAEGTAFYDSFFYYDCNVTVSSNTPELSARNAAVAAQAIGLSGQVHSEFFFANGSEMSNQFVAYNFGLPFGTVQNNSATGMAEQLSRFAIGVVAAAAQTNPAKVVDGAQPAQGFRLEMELPVMFSVILGLIGGVQLALVIATAWVCRQVEMPEEVDLARKEEIRRRYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8S8</accession>
    <name>A0A6A6P8S8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_280890</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Cytoplasmic vesicle</location>
            <location evidence="13">COPI-coated vesicle membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the COPG family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8S8"/>
    <dbReference type="OrthoDB" id="1074925at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000046">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000071">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1480:FF:000001">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000008">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032154">
        <property type="entry name" value="Coatomer_g_Cpla"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16381">
        <property type="entry name" value="Coatomer_g_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037093">
        <property type="entry name" value="Coatomer_gamma_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="15">
        <location>
            <begin position="21"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="16">
        <location>
            <begin position="653"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer subunit gamma C-terminal" evidence="17">
        <location>
            <begin position="808"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="609"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2460182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="921" mass="100924" checksum="7C371E4A1D4EC1AF" modified="2020-06-17" version="1">MSYNKKDEDADGAIVKVDRTSVFQEARVFNTSPISPRKCRILLTKIALLLFTGEKFPTNEATTLFFGISKLFQNKDASLRQMVYLVIKELAHTAEDVIMVTSSIMKDTSVGSDVVYRANAIRALCRVIDASTVPAIERLIKTAIVDKTPSVSSAALVSSYHLLPVARDVVRRWQSETQEAASASKSSGGFSLGFGAGSHSSLAAANTNFMTQYHAIGLLYQMRTHDRMAMVKMVQQYSAAGVVKSPAATMLLVRLATKLAEEDTNLRKPMMQLLDGWLRHKSEMVNFEAAKAICNMHDVSDAEVIQAVHVLQLFLTSPRHVTKFAAIRILHNFATFKPDAVRSCNPDIEALITNSNRSIATFAITTLLKTGNESSVDRLMKQISGFMAEITDEFKVTIVEAIRTLCLKFPSKQAGMLAFLSSILRDEGGYEFKRAVVESMFDLIKFVPESKEDALAHLCEFIEDCEFTKLAVRILHLLGVEGPKTAHPTKYIRYIYNRVVLENAIVRAAAVTALSKFGVGQKDPEVKSSVHVLLTRCLDDTDDEVRDRAALYLRLMEEDDELGVRFTRNDSMFSLPVLEHQLVMYVTADSKETFTTPFDLSKIPVVTREQADAEDRNKKLTTATPTLKAPSTGPKPTPRGGADAAASATAAAQKYASQLQQIPEMAAFGGVLKSSLIVELTESETEYVVGAVKHVFKNHVVLQFEVKNTLPDTVLADVSVVSTPAVDEDGDVTLEEEFIIPAPLLKTDEPGTVYVAFKRMEDTGVFLAASFTNVLKFTSKEIDPTTGEPEESGYEDEYQVEDLELSGADYVIPAYAGSFENVWEHSNGEEAQETLQLGNVKSIAEATEQLPKALALQPLEGTDVALNASTHTLKLYGKTITGGKVAALVRMAFSAKSGVTMKIQCRAEEEGIAPLVVASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8U5</accession>
    <name>A0A6A6P8U5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_413397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8U5"/>
    <dbReference type="OrthoDB" id="1696305at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050896">
        <property type="entry name" value="Mito_lipid_metab_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434:SF1">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="793" mass="85763" checksum="E4A222C90051536A" modified="2020-06-17" version="1">MQRGLRPLWRAAANTATATPTTSRDWVAAGQHAALPVFLCPALATTRHCGRTGRVTPLTRPTRRFATARAAAAPREHEDEARDVDPLETFPHVEEPESAALAESSAGSSGGVGGSGREEGSGGSGETGESTRRVLPPSCPGCGAPTQSVAPDEAGYYNLRRAAVRNWLRPERRQAREAEDEKFASALGNADDGLLAKMGLDRESVKDNPAPPPCDRCHALLHHGSAAQTPIYHPTMSSLRAVLSSSPWRRNHIYHVVDAADFPLSLIPDLTSHLDRVARLRGQNRRSKSVRWNRGRPVDEVSFVITRADLLVPKKEMLDKLMPWVSEVLRDALGRSGRRVRLGDVRCVSAHRGWWTREVKEKVWERGGGGWLVGRVNVGKSRLFEVVFPKGRSDGAAVDFDRLRGDAEREAALADPDGDALAPQLQQQESNESDFFPLSANPSSSLLPPAPSETPYPPMPTVSPLPGTTASPIRLPFGRGRGELVDLPGLARPSLADCIARPYKEDLVMTSRVAAPRTAIKGGQSLLLGGPLDGRPPDMWAHAFVPPRLGPHVTATPKAVAVQAGRRALPPRVFPPDAVPPHVAAAARKARTVPLRWDVTRAQAGPLTSKAALRLKPARLPFVVWAADVLVEGVGWVEVGCQVRRRWVEDGLREAERRVRANLEAGEGVEKLADEEREGGGGGGETVAFKPAAAAKSEGEEDGWLAAAEAPDEAILPEGVSEEDFKEMVVEEAERMGVYPEVDVFTPEGKFIGVRRPMGGSIIAAPKKNPKTSKKRPRLSMKAVKARRRPKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P926</accession>
    <name>A0A6A6P926_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_164659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P926"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="103" mass="10943" checksum="65605C11D1CF6D5D" modified="2020-06-17" version="1">MIGLVDYNPRCQRTSTLYGAASLIRTSPTATPLSTLRTTETAFRSWSSSKKSNLALSPQTSSLVTPPTTSHGSGLPRATASWMMMAILNGTALASEVSVELRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P952</accession>
    <name>A0A6A6P952_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_315779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P952"/>
    <dbReference type="OrthoDB" id="422206at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="479" mass="51129" checksum="DAD735F290378128" modified="2020-06-17" version="1">MRKGEGRRGGGEVGGGAGGGGHYHHHHHHHHRVYKRRWFGLVQLVLLNVVVSWDWLTFSAVSTTASQFFNVSENAINWLSIGFLFAFVVITPVVILVLHRGPKPSIIAASVFALVGNWIRYAGARAGNGNFGVVVFGQIVIGLAQPFVLAAPTRYSDLWFSDHGRVSATAVASLANPLGGALGQVIGPLWTDEDPANIPNLVLYMAIISTVIAVPSFFIPAAPPTPPSASSALPKPDLKTTFHALLRNRSFPLVFIPFSVYVGFFNAFSSLINQILAPYSFSEDDAGICGALLIFVGLGAAAVTSPLLDRNHAYLVAIKALVPLVGASYLAFYWAPPTRDLAAPFVVAAVLGAASFALVPVSLEFLVGLAWPASPEVSSTVCWAGGQLLGGVFLVVMGEMKAGGGRGDGWGPPENMQRALVFEAVIACVVVPLPLLLGVRRLGFGDVGRERLRLDEEERAREREEDAEEERRGRADGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9I4</accession>
    <name>A0A6A6P9I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9I4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025545686" evidence="1">
        <location>
            <begin position="25"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="31334" checksum="86858E4AD161D0B1" modified="2020-06-17" version="1">MLVLEKFLWLVSAFAMLNAVAAVALPSNDAVAGDVIANGTTTDVVPANTAVSSNETPDRDVCSGDFEFFNLTFCADFNYKRCVYRTKVSEMCHSFEEHPALDRQVNVLVLEPNVVCFLSPAYDCSRAALVTIETTFVRFMVPHGMSSYMCKKNYPPVEIDATTVKRDVDVSTDIGPANASSTDLVLTDGDTADWDVFYVYLCQEAEFHACLKVLFVSDQCYQAGAKVNPHIVKSFRIPHNAYCYISPYDDCRSLILIDSDVSNVSRYFKSRLMGMRCWLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9N2</accession>
    <name>A0A6A6P9N2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_384100</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9N2"/>
    <dbReference type="OrthoDB" id="3238762at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF9">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 15" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025332323" description="AA9 family lytic polysaccharide monooxygenase" evidence="16">
        <location>
            <begin position="19"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2460497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="241" mass="25312" checksum="BDF804064E3F5FBD" modified="2020-06-17" version="1">MKAFGFAALLATATTVSAHATWQEMWVGSTDMEGSCVRQVQNNNPVTNVDSNDIVCNVLANKSPPYGAEGVCEVEAGGDLTVEMHQQPGDRNCNNEAIGGQHYGPVMVYMCKVDDATVDDGTGCSWFKVAEDSFSGTTESWGTEILNANCGKKAFTVPADLAAGDYLVRSEAIALHTAQSSGGAQFYMSCFQVRVTGGGSANPTGVKFPGAYSASDPGILVNIHSQGFNSYEAPGPEVWTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9X6</accession>
    <name>A0A6A6P9X6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_131906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9X6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="24789" checksum="9797290666C250A7" modified="2020-06-17" version="1">MSKYRGTCSSMVFKLIIEQFPSVTMPPVLPYYVIEKQCLLLPNNHFITQVHEPKPLLPNRISAQHDHHSPYYVCISPSPPRWLEQPSPPKTAARSRRPPSLRSSSQTPSPRPLGFRDPNHSATPRSARMKHGAGSAGPLAAPATTAALVVFFCRVGVWGGRPWSFYFVINFGGGGGVGLLVVEGSARVWGNARNICILLERERKKKGNYFLWGKSRRGGRRGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAA4</accession>
    <name>A0A6A6PAA4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PXA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_279049</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAA4"/>
    <dbReference type="OrthoDB" id="120967at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06876">
        <property type="entry name" value="PX_MDM1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="7">
        <location>
            <begin position="109"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="5">
        <location>
            <begin position="428"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="871"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="621"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="698"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="835"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1264" mass="139982" checksum="D6C7F2F433DFA7D7" modified="2020-06-17" version="1">MDRLRRRDVILASIAAFVAWGFVTHWVPPLRFLPYAYVAGVASALGLYLWLVLSTAKCNARPGAGGVGGNSAFRGPRNVAFLSPALWRAEKRALKRRAEYKPVSIYPQSKKISRSIDEILGLIARDFVRSWYGNISPRPMFPNEVDRTVRAALVNIRERLLQVDLVGMVVSRVVPIITSHLKDFYEAEKLVRGRRLTLNVTESEELDLAIAGKFRDGKIHPAASLTYSNTKHIQQQYLRGVVMRLLPKVLPANMTTSTAAAILVKEIVACAVLFPLFQLLADPDTWNQLIENYGRTVLQDRTTVRKLRAALDEHAPASPKATRSQFPKLSPNDNERMFERFIRAIKRCNSLADARRFRSEVASELRKESAVEGQDQVYLRRLEAGKRVLDQRVAYLGAGGSTKKSRLPVQPLPNSATPQTSSRLENASLKDVLYDASGLSYFMECMDRQGLMRLVQFWIVVDGFRNPLELDTDDPRETLGQYQKWSDSDRIDLAQINEAYLSKPELKIPSASRQAVKDFLKAGSNATPLQYATARSAVLKAQTAIYETMQHPHFDNFRKSDLYFKWLASDDRTKASSLSPKTTDDIPDMASIIKEPERPTAKHGVTSANLRFLQPDLRRTAASSSDLKGSGGKLVDPGLPARRSLDDGRAPLFDDDYDSDPLARSTASLESEPPAGNDVQVVDAMQAALNDIMENEEHDKDSLFSDLSLHSPQDNDSTRGSLDLPRAASPAPRKDAEKPSLASLGLVSTPKRHGAVFSDDLFGDEQEKFIEDEREDSEVDEKPIEDEIHEAAPGDLGLAEAIDALSLDIERLVTQESIVDSLTRKAELTNNAAELRILKKSKASLQREIHRKELQRQQYIVQESENSLYGRASVTIQSIMLGTEDDGKEYALYVIEVKRQAGELMPAAAWVITRRYSEFHDLNKRLRARYPQVRNLEFPRRQMVLKLQKDFLQKRRMMLEKYLRDLLQIPAICRSRELRAFLSSSAIAPVNGTSAGNAQADSRDFVSRIYNSVTDGMDEFLGNIPVLDQLSLAGQNLISAATSQLNAQSGGGSANSTPTSSTAPRIPSNLVASAVATGSQADPDAEAQAELAAFEASSAASSQQLEPFVKPICDLFLEAFELNRDSNWLRGRAVVVVLHQLLGGTIERKVRESTRAQLQEDTVVKYLDVLKEAMWPGGKPKAAPGVAGGTIRTAAEKAKSRREAGVVLATLVPELAGSVVGRGNAGAASRRFLATMNNQRLNTHLVFTLLDEFVGILFGEAVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAI3</accession>
    <name>A0A6A6PAI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_135362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAI3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="134" mass="14450" checksum="58884705C42BE4A4" modified="2020-06-17" version="1">MAPSDHHGSAAGQHHGNHARDPSSANLQPRESADAVRLSPRQHVIAKHLLTVSALCAAETVVAVEHAFFLLDFIAHWLLHLTGPLGQGRNFSPARPETATAAPIKASPAGNEYAAARGPKWNRRKANKRNYSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAK0</accession>
    <name>A0A6A6PAK0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_314818</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAK0"/>
    <dbReference type="OrthoDB" id="409625at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2460936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="84" mass="9331" checksum="B5C66AAE60D6A516" modified="2020-06-17" version="1">MSTAPLNPRPFLNSLVGGPIHIKLKWGHEYTGRLVAVDSYMNVLLQGTVEHLKDGKSETLGQVLIRCNNVLWIVRGKEDTEMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAK3</accession>
    <name>A0A6A6PAK3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_376685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAK3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="18389" checksum="3B57A2CC86BE5EA6" modified="2020-06-17" version="1">MEDNWSHDPNIPTSALEPELLNIEGSVMRAEHDLAVLRHHVQDFAFSNGFNVLNKCYSYLNAQRAWHDSVPFALQFEPNILAEDAHSAISNDIIAIERSQQLVEIYTDEEMVEMELNRLAARDLELYRKEPVPYELSRMWTEDHSEESGHAPYDLCEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB93</accession>
    <name>A0A6A6PB93_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Lariat debranching enzyme, C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_141066</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lariat debranching enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB93"/>
    <dbReference type="OrthoDB" id="407609at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="14">
        <location>
            <begin position="352"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="284"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="328"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="515"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="559" mass="61831" checksum="510AA2FDDD6E654D" modified="2020-06-17" version="1">MATSTLRQPIRVAVEGCGHGTLNSIYASVRKTCAARGWNGVDLLIIGGDFQAVRNAYDLNCASIPEKYRQIGDFHEYYSGARVAPYLTIFVGGNHEASNYLQELYYGGWVAPNIYYMGAANVVKLGPLRIAALSGIWKGPDYRKPHFERLPYNSSDVKSIYHVREIDTRKLLQIKTQVDIGISHDWPRGVEWHGEWYTLFGVKRHLEADARSGSLGSIAAKYVLDRLRPAYWFSAHLHVKYAAVIQHDAQTEKSVVEMADAPNPQKNADEVDLKLDDDDVAKGAEAKSANDDEIKLDLGDQEVPPEPPEANGQSSALVAGVPDDLRAQLPASFNRSPPSPNDQVGPSSARPQPPPPGITNATTRFLALDKCLPNRDFLQLTEIEPLTHLAADEDSNAPLQLQYDREWLAITRVFARDLQVGDPLTQVPPDKGTEFYRPLIAAEEAWVDDHIMKAGKAAVPNNFVRTAPVYDARRGISVGPRMPREYSNPQTQQFCQMLHIPNPFHADEGEIDARIRTGPRPEPSNFGREHGRGGRGGCSGGRFSRGNFSGRGRGRGRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC36</accession>
    <name>A0A6A6PC36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_418546</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC36"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.15.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit delta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048938">
        <property type="entry name" value="ATPD_C_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21334">
        <property type="entry name" value="ATPD_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="F1F0-ATP synthase subunit delta C-terminal" evidence="15">
        <location>
            <begin position="124"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="17663" checksum="3016691B12E1B5F5" modified="2020-06-17" version="1">MSALRIARTAVRARPAAASIRTTFQRRGYADVAADKIQLSLTLPHQAIYKSTNVVQVNLAAESGEMGILANHVPSIEQLKPGLIEVIEESGGSKQFFLSGGFAVVQPGSQLSINAVEGFPIEDFSADAIKNQIAEAQKIAGGSGSEQDVAEAKIELEVLESLQAAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC98</accession>
    <name>A0A6A6PC98_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_418570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC98"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="18695" checksum="49EE42C1E6C42EB5" modified="2020-06-17" version="1">MLLSRLYSPLPALPPSLGGGHAKKACAYALSQKSDVIARRTSLVTRLQGCLLFVEALRRRMTRGTRPSWEVKCSQSAFGVTAPARGPGKPAAHRPNARDFVMEATENRDSSSITFWVALSPCPIGTVPGFKPPLAEENIAASYHTLRPPAVRPSIRLAWGEGIKDLSRPSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCB1</accession>
    <name>A0A6A6PCB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCB1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="20102" checksum="39C569312F4C87AF" modified="2020-06-17" version="1">MRIRGGIVGGSIVSGCGEATGRRVGWARRGIACAPSRATGRRCGGNCRLDDGGSSERGGEAHAVRPAASVVEDERGRAGSRDGRAPIDDEGIAPCERLQQAHSDRAVQNKSTEKGAVKGGYDKREGKGKMIRSALATPCRCPSVGSSASWDCNPTASDETECMRTAQPDTVLQDQWDGATRERGRESLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDI7</accession>
    <name>A0A6A6PDI7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pex19 protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_87781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDI7"/>
    <dbReference type="OrthoDB" id="21292at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="341" mass="36492" checksum="766946642159B0BB" modified="2020-06-17" version="1">MAEQKKPEQPVESAPDPDSDDLDELDDVLDQFADKPGAHAPDAPASASTSKPADTTSQTASGSREASPAPASQRPSATSQTEADDVDDDDLEKQLQAGMAELLGGLDSPEMQKQFEEMMKGFAAADAASGGMASMSAKEAAAGGGAKDSGGPSAASVADESFQETIRRTMERMKVSEDNASSAAQADSTSGDDFLAKMLREMEKGGLDPSSAGMGGPAGSDEDFSKMLLGMMEQLTNKDILYEPMKELHDKFPIWMAENRDKGKVSDEDWKRYEEQEMLVTEIVGRFERDGYKDENPEDREYILERMHKMQAAGSPPPDLVGDMNAAQEALGELDAGCPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE37</accession>
    <name>A0A6A6PE37_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_5707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE37"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="96" mass="10575" checksum="175D57EA586B3AC9" modified="2020-06-17" version="1">MARRAARCRCLSAVQAQLLPAGRTDRGRGSLEAVLAASAGARQAPQGCVCGRQRDGSRYAPPTMDATCVVDFKLMHDRWITKWPFSRKKEVVEPCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE57</accession>
    <name>A0A6A6PE57_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uracil-5-carboxylate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_295586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE57"/>
    <dbReference type="OrthoDB" id="191270at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000055">
        <property type="entry name" value="Uracil-5-carboxylate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="4"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2462047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="362" mass="39211" checksum="A587F2B6E23EFB57" modified="2020-06-17" version="1">MPIVDIHTHVYPPSFISLLRSRTAVPYIRNFPDAPSSSRLIILPGEDDPSTPSTSRGRPIGPEYWDISRKVAFMDAHGIDVSVISLANPWLDFLPAAEAAAAARAVNDDVNALCGTHPGRLFAFGTLPLSGSADEVAAEVARLARLPYMRGVIMGTSGLGKGLDDPALDPIYAALERHRQLVFLHPHYGLPPSVYGPRAAEYGHVLPLALGFPLETTIAVARMVLSGVWDRFQGLEVLLAHSGGTLPFLAGRIESCVAHDAHLMKEGKTKNRRSIWDILKKNIYLDAVIYSEVGLQSALAASGSDRLMFGTDHPFFPPLEAGETEWLSVKTNYSAIKTAFGEDRKSADAVLGDNAVRILRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE79</accession>
    <name>A0A6A6PE79_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP-binding protein ypt1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_11329</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Preautophagosomal structure membrane</location>
            <topology evidence="8">Lipid-anchor</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE79"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000069">
        <property type="entry name" value="Ras GTP-binding protein YPT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2462305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="22260" checksum="7CA9F197EEA8E660" modified="2020-06-17" version="1">MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDVTDMDSFNNVKQWLQEIDRYATEGVNKLLVGNKSDMTDKKVVEYTVAKEFADSLGIPFLETSAKNASNVEQAFLTMARQIKERMGTSTVNNKPSVPIGQGQGVQSGSAGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEF1</accession>
    <name>A0A6A6PEF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEF1"/>
    <dbReference type="OrthoDB" id="5288586at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF2">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="10255" checksum="5715925B3F560441" modified="2020-06-17" version="1">MQIACSRLLGFSELPTNVLTSTYADLAGDAGVLRLDNPKRNRRLGAAVLLLGGAISGGWLMRAGIGAHGVLWVAAGLKAVVVVFVWVALSPRVGVDETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEQ1</accession>
    <name>A0A6A6PEQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEQ1"/>
    <dbReference type="OrthoDB" id="10251048at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000069">
        <property type="entry name" value="HAD-superfamily subfamily IIA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF4">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="47745" checksum="C100225D1AC6C91C" modified="2020-06-17" version="1">MAAPSLAVPVQGNPRFTRRLSSREATRDSLSQGPTVVVPPQQLMGKPSESHEVAASMEIARHELESSRTPSPHTPSETIVTDKYAFAFDIDGVLIRGGEVIPEAKEAMKMLNGENEYGIKVPYIFVTNGGGKTEQERCVQLSNQLQLEVSPGQFICGHTPMREMAQKYTTVLVVGGEGEKCRHVAEGYGFKDVVTPGDIIKDNKDTTPFRKLTETEYQDSRARKFSDVEIEAIFVFADSRDWAADQQIILDLLMSKNGRLGTRSENFDEGPPVFFAHNDVVWSTSHDLTRIGMGALRVSLEAMFKAVTGKELKTTAFGKPQIGTFEFATRLLQQWRKDTHQIDSPPDTVYFVGDTPESDIRGTNDYDSIVGNTWYSILVRTGVYRDGTKPRFPPKVTVDNVLEAVKHGMRREYTKLLKAKMEESAVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF05</accession>
    <name>A0A6A6PF05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="7">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_383048</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="7"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PF05"/>
    <dbReference type="OrthoDB" id="418791at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000045">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.270:FF:000002">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054692">
        <property type="entry name" value="LeuA-like_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002991">
        <property type="entry name" value="PRK03739.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911:SF1">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22615">
        <property type="entry name" value="IPMS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="14">
        <location>
            <begin position="33"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="592" mass="64666" checksum="73378FD0A215A044" modified="2020-06-17" version="1">MPMLADPSKKYRKFQPLHLPDRQWPSRTVDQAPRWLSTDLRDGNQSLVDPMDGEQKWNYFAMLTKLGYKEIEVSFPSASQTDFDFTRKLVDTPGFVPADVWLQVLSPCRKELIRRSVDSVKGAKKAILHLYLATSPCFQRIVFDMDNAASKALAVECTRYARSITKDDPSQAGTEWAYEFSPETFSDSDPAFVLEVCEAVKEAWGPSEDNKIIFNLPATVEMSTPNVYADQIEYFCRGISEREKVCVSLHPHNDRGCAVAAAELAQMAGADRVEGTLFGNGERTGNVDLVTLALNLYTQGIHPKIDFSDIKSVIDVVEKSNKIPVHPRAPYGGQLVVCAFSGSHQDAIKKGFQARKAAGLSEEDPWEVPYLPLDPQDIGRTYEAIIRVNSQSGKGGVAWIIQRHLDLDLPRGLQIAFSRIVQKQADAIGRELLPGEITTLFQEAYLARPNPRFALVDYDIIADRGASPAPAGGAGGGAPAPSSGRNLKRMFRGVVAIDGREHNLAGTGNGAISSLANALRGLGIDLDVADYKEHAIGEGRDVKAATFIECTAAGQRDKVWGVGIHEDVVQASLMALLSAASSFVARLFESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PG97</accession>
    <name>A0A6A6PG97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_368446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PG97"/>
    <dbReference type="OrthoDB" id="1861185at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071140">
        <property type="term" value="P:resolution of mitotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090656">
        <property type="term" value="P:t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="2">
        <location>
            <begin position="128"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="601" mass="63253" checksum="1DD7BF15A6B1F900" modified="2020-06-17" version="1">MTDLHAVLPAFDTRPFTHLLPSLERAAVSLADLLTLDPADVARRAQLPAAQVRVLVEAVAAALRADVGWTVEEGEEEEEEEEEDWAGGGGGGGGGRRARDEADGEDDDGAGASAGAEDGGRERRDVAEWRSVSLLDARIDEGLGGGIPTGYVTEVTGESGAGKTQFLLTLLLSVQLPPPAGLSKSALYISTESALPTVRLAQLLRNHPRLQQHHQKRDNNPKTATTTTPSLSRIHTISTPDLEAQEHILRYQLPVAIARYNVGLVAIDSIAANFRAEFDVPAPAADEPHQEQHGEQRRQAAPAQGRPTKRRRKEASLACRARLLVQLGGLLRGIARREGVAVVVVNQVADRFGSENGRNGGIGPGGGYNSYNHSYVNSGNGILNGSGNGCGNGNGNGNGTGTNLTTPTTATPQPRPTAPTSPFPPPSTPPLPSLPNPLTFDHQQRFFTGWGDDEPPPLLPSASASASTSAFPSSAQPNLKTPALGLVWANQIAARVALIKTPHDQHQHQHQHQQQLQPQRADEQPAAAAGGGVSSGWRRTLRVAFAAWAAASPPGEGVAFEITGEGVRSVVARVDEWGGCGERGGEVAGCGSEMGAKRWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKU4</accession>
    <name>A0A6A6NKU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_375692</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001718">
        <property type="protein sequence ID" value="KAF2452259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKU4"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="65" mass="7227" checksum="9961299D9A9FB968" modified="2020-06-17" version="1">MRDLEEDRQLPVSQLLEHVVAVKEKVLAEEHPSPLASRHSLAIAYQANGQVQKAVELPEHAVALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL67</accession>
    <name>A0A6A6NL67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_172498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL67"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="22015" checksum="4C7D5DC18DACAC25" modified="2020-06-17" version="1">MAHTLSLLPGLAPNSPIGSTPKIPKPSRSRAPTQHCDSLEHRNTTPSGTVGSLLVRINIIRYKEATEGGEAIQAAGHALTRPSKPRIPDPGLEALNLNHKLPPMFCKRLAQQSPSASRRTKRNESSVFSVGENKCNRYFETVNSRGKGRAQRSIEKEKGEKKQEWTIQDRKGNNVESPSRDYNVYAHPQKTSRQDNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLK1</accession>
    <name>A0A6A6NLK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_157682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLK1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="15667" checksum="5D36E2730C597FA2" modified="2020-06-17" version="1">MNYVVVQSRREEPLGRPKYCDRSRHVHWACMCILVAFICISPPVAQARPAGPGLETPEKKRQRLCWTTNRVLPRTHRHASFRVSLPSSEAAGLNPHVTIASLVANRPAYRLLKPARSSRAPAQPNWFFFRFPRTHTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLY1</accession>
    <name>A0A6A6NLY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLY1"/>
    <dbReference type="OrthoDB" id="3511549at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="137" mass="14629" checksum="6E4B4D628631C3E7" modified="2020-06-17" version="1">MPTRARTAANIMAEVPRVVKGSSLTQSGGQTAGMVRMNAVHGMSDRICSLVMTAEPHTSSVVHHHGDQDTVVYAVRGRGAILSGPNGSNRHELAPGDFAFIPAWAEHQEVNDGEELVLVVMRTGREPETCSLDGWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM97</accession>
    <name>A0A6A6NM97_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM97"/>
    <dbReference type="OrthoDB" id="3902208at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="121" mass="12636" checksum="CD68E5BF18F339FE" modified="2020-06-17" version="1">MAGGDKEHIPQEGKKEDQDQGTGGFLSPLGDPLGNALGAGLRPIGATVETITKPVRDGVGNITKPALGPATGAKEDKMEVLGGDNKDSYAHGKDSVAGRLQTAENPLGLESQERWGFREEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NML3</accession>
    <name>A0A6A6NML3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NML3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="60" mass="6158" checksum="88A1C9CA6ABEB538" modified="2020-06-17" version="1">MHSAHPPPAVDGCAANRTPRVYICSTRQAPRPPSTAAPGSGSYVLPRSSDRPRSGATGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMQ7</accession>
    <name>A0A6A6NMQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_144342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMQ7"/>
    <dbReference type="OrthoDB" id="4725598at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24839" checksum="D83DF96616767D60" modified="2020-06-17" version="1">MPRRKDFLGRGRYGVVHGTRKYAIKQIDDEDVFHAEVDAYRSLNKVRSLRGRIPILHGIDPDKQLLYLQHINKPTLQQKLPDEPTLRQIRQRVLETISIIHECGWCHGDINLGNIFASGLLFDFSHAHPKNKLSAQAWEDFQKKDRRDTKSYCLQAVGLKKLEAAIALLDSGVDGLPRQAELAELLHHSKSSPELALLGYPVIRARHCTTEYPRAPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMQ9</accession>
    <name>A0A6A6NMQ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome c oxidase subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cytochrome c oxidase polypeptide VIa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_357103</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase subunit 6A family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMQ9"/>
    <dbReference type="OrthoDB" id="5947505at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.95.10:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 6A, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.95.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001349">
        <property type="entry name" value="Cyt_c_oxidase_su6a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018507">
        <property type="entry name" value="Cyt_c_oxidase_su6a_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036418">
        <property type="entry name" value="Cyt_c_oxidase_su6a_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02046">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01329">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="135" mass="15274" checksum="5012BD222368EEE1" modified="2020-06-17" version="1">MLARTAAATARVVRARTAAGPAGLRTYSAEVGGQPLKGPADNAFNRERAAVKAHAAATSDLWRKLSIYVVIPALLISGANAYRLWNEHWEHWEHMPPLEERPAYPYLNVRTKNYFWGDGDKTLFWNDKVNFHKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMS8</accession>
    <name>A0A6A6NMS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMS8"/>
    <dbReference type="OrthoDB" id="342264at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="52802" checksum="26A5655B22363E16" modified="2020-06-17" version="1">MPRLTNPRFSEFLEEDNFGDLGLSSPPISKNAPKIFGHRDIGEDAELLKSQSPECDLESEEEDDLLNLADQPDLPGSGKGLSEARKKPHSNANEFEDYPPPKSLVKITTDAMESTSDIEGGIGGGFANALGVAAGDLPSPPTDSSHKCSGVKVVVEIKRSIAEVLASDSADEASSPRGPKRTRVKTRVGSVVGRTERDKPELEEHDRHDIDQREPEIEAPLRRNELRFPRQKADVPSPNVLFSQTMWEKDFMRFIHFIPRNGGASKPVYDAEWMKYGNIFCVREDDIVRSPRLIFSLAAGRYIVTEKWIQNSYNAGYFLDPKKYLPEEHVLKVRSFKTTVEEASKVATRRPLKGLSIYITPKLSKEYRGEAAIVLDICKRAGASFVFNQGHSRISARQLHSGDWIAFVHDGVDFDGAQLIKRKGDVRCYHRDFLSLTVLRGKFVDDQGYRVTPFMDVWEKNSQRKKAPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN01</accession>
    <name>A0A6A6NN01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_375429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN01"/>
    <dbReference type="OrthoDB" id="5305647at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="256" mass="28981" checksum="4CA3B66FEB4A99E5" modified="2020-06-17" version="1">MAQGHSQEQGQTPTAPVAPPATPPTAPQAENVPGSQRASGNTTHRKGEGKGKEPVYSVAENSTGSVASDDADETLQCPDCSRPFPSVSRLNRHKRCVHDKVNDYCCPVPNCPRHKRGWGRKDQWVTHIKKHHPALLEGAEDPDQGYSVEEEEEEPPRKLTRKRKSQSAVDVAETEADREEPEVKTSSGAKSKLRAERKALEHERRLRMKAEEENEILRRKLRNREEMFLEMVAERDRELDQLKMHTERKGKTDTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNH8</accession>
    <name>A0A6A6NNH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_152526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNH8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="187" mass="20471" checksum="665E058AFC939DBE" modified="2020-06-17" version="1">MRCHAAPYNAMSHEHVQGAFRGLHGAPPCQVTAAIKKFSGRASPTTKNQTGCDARSLRLPPNSGRCDEAPVADATSHLDRISNHAQIRHVLSGQCSISSGIVSPASSNGADSRATSEYSTAHTLHRCCQARATNREVDSDSIYLRREAYTPKDAYGNEAPRTINDINARRYDLRGIFALHLMRRRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNQ6</accession>
    <name>A0A6A6NNQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1765-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_293183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNQ6"/>
    <dbReference type="OrthoDB" id="296767at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013887">
        <property type="entry name" value="UPF0592"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988:SF1">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08578">
        <property type="entry name" value="DUF1765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="763"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="928"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1015" mass="110959" checksum="B9DBFFF580D01658" modified="2020-06-17" version="1">MSKSSPAKSLSKLRRRSWMSSSANSPSRSPSPSKRNHHLRGAGGAPTAAPGSDDSLVNSTNESGAAAASAGGARSRRRSIEAQAPPPPRSPSVPKSFSTDRLPSLGRWSSSSQQQQRAGESNGAGGGKISGGGGVPPVPGKLSSEKLRGLGVEPPRKKDELWSVFRTLDADLQKFQAKSITLKANVVRSSLMPFLKSYGAHPSNHKLRPEDLDRRANILNRWWTSLLEVLHGRNNQSIGGTDRPVILDGITGIMERPEWRYPPSPYAPLADRADITITPRSSESVSASSGSSDFLTESVHHNVRNIFVQNLIAQMSFVVDKMSLRTAPASLVTFCGKTCAYAFMFCPGFADVLVRLWNPTLDGMRRIFDQAGAQGRWELSEAAKDLVSGFPAHLKSLKYPSLVKAHRDLRRPVSSPLGTANWQWGGPWVKRWSGKESDLFYVFVKHYHILIMDFLPLETTKTERLGVPGLIMVHAQILANVEATIHRHAQSTQEDTNSGPSPTFDDVLTEPDASASAMPMAPVNATRLMAENRLIMLIRDFLSERCSHISRAREAFAEAFNDILRSAARRTSMYDHAACYTLCDFLEEALYILVRYEQITDGAHAVLDWPFWLSVFRAMADSHNTTTEIRLYAFLYAVWGTIATDGRRKADVCAKFLLEPGFFESRFNHWCPMVRAYYMRLLCWRIARFDGDPGDEDLEILETLSNRLGEVWAHYLYMKDEAEANNIVAPPTAPSNPAPSRRILIIRTDAPAPIAGGTFLSFDGLMSPSRTNQSPTLMRQPSLSAVPDTASISRSSTDSSDLDEDSSKKKWGLLRTIIGSTSKSRSKSRSPDPPRHGSGTTSGKGGGNGNGNGGGGGIPSSGPLGGTAGNRRTSDASSDSSSSSQQILTHRAFCFKFSLEWIDKRFPAPGNIRLHPPRLPMPAQMFLQQQQRAVATADQASPARSGSGAGAERPEGPAAGSSRYAGRALAEWSLLVNECQCFFERRKNEGVPTNKLVESPTLGVESFRKPGPRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNV8</accession>
    <name>A0A6A6NNV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_374978</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNV8"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="8">
        <location>
            <begin position="35"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="7">
        <location>
            <begin position="198"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="372" mass="39007" checksum="B6E9DF99B8007EE7" modified="2020-06-17" version="1">MSTTEIPSTMRAQFLDSYNAPFALRTAPVPAPTDPHDLLIKVDAASYCHTDAVLAAGAMPPHPPAFPHVCSHEFAGTIVRAGPAAPADLQPGVPVGVPGRSLHPCGTCFECAASPRFDADPPGYSVDCPSASNNGISAHGGFREYAVVDARQVAPVPPALSPVETAPLMCAGVTVYAAILKSGVRKGQRLGIMGCGGGLGHLGLQFATKMGLRVTGVDAADGPLALAKGLDTGADVVDARKEKAEEVRRRLGKEDGKELLGEMGLDAVIILPESQQAFDYGVDMLKNHAKCVVVSFPQKGFQVSAFSVVFRDITVVGSLVGSNKTLREMLAFAAEHNVKAVLRTYPLSKLNELVEEYHKGSGGKLVVDMSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNX2</accession>
    <name>A0A6A6NNX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_124394</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNX2"/>
    <dbReference type="OrthoDB" id="5283415at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="26"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="378" mass="42604" checksum="D4AD0C2DF21F94A7" modified="2020-06-17" version="1">MNEDVDRTAATLILVFPSASTAFVALRLISRYLNRSYGFDDTVILLAWTITIGQAVIQWQMARFSFDLTPSEQRVASQYNLAIELIYNPILMLVRTSAILFLYRLGDVRRGIRYSLHALNALNIGHGVATFFTILFQCMPVNYAWESEILDARAQRAAGADANGVINGQRVTGGTCINREQFFLVSAGLSTMLDVLLLTIPMKMTWRLQMPCKRKFAVVVILSMGWIVTGISISRIIIFYQIFASPDFNTNFGYNFTVSSIENNMAIIAASIPALSAFWKRIAPRCWRTFSDGEPSGPKHYNDVVLPRKLSASSVTATTATIPDDTVRDDKVYRIDELDFERDRRMRGEGVHSWIDPGSLWVGRSESEGRRSRQDVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPA2</accession>
    <name>A0A6A6NPA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_327373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPA2"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="42"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="131" mass="14938" checksum="7E3AC92D3B467BCF" modified="2020-06-17" version="1">MFVYKPLSNPRDSIRLLRVVGEFQVVGVCLIMSFHIDGCLPYLALSYAWDSQAADKWIWLDGKKFDVMSNLHDVLGTFCAIGLRQWVWIDTISVDQNSDAKKSQQVQPMPSIYKRAEKALGWAVLQTRSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPA7</accession>
    <name>A0A6A6NPA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_292857</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Involved in mitophagy. Required for the switch to necrotrophic growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The mitochondrial prohibitin complex consists of two subunits (PHB1 and PHB2). The subunits assemble into a membrane-associated ring-shaped supercomplex of approximately 1 mDa. Interacts with ATG24/SNX4; the interaction is direct and plays a role in mitophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prohibitin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPA7"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035632">
        <property type="term" value="C:mitochondrial prohibitin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="6">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00053189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00066275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="280" mass="31195" checksum="F56DDF320169243C" modified="2020-06-17" version="1">MAQALNTLYRWAIPLAVGASFVQASMYDVKGGTRAVIFDRLSGVKEQTVSEGTHFLIPWLQRSIIYDVRTKPRNINTVTGSKDLQMVNLTLRVLHRPEVGMLPKIYQNLGQDYDERVLPSIGNEVLKAIVAQFDAAELITQREAVSNRIRTDLLRRAQEFNIALEDVSITHMTFGKEFTRAVEDKQIAQQEAERARFIVEKAEQERQANVIRAEGEAEAADTISKAVAKSGDGLIKIRRIETQKEIAQILASNPNVTYLPGSGQGEQDSKGGNFLLGLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPF2</accession>
    <name>A0A6A6NPF2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPF2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="88" mass="9836" checksum="18AACC27FB6E6328" modified="2020-06-17" version="1">MWCRRPAHAGPRAGLVSQQPLSRAARPPRKQKTAQATPLCDAAPRRTYDEHATYPTYRACVGACAWQTCGRRARLRATLHRPRRGGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPJ5</accession>
    <name>A0A6A6NPJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase HEL117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPJ5"/>
    <dbReference type="OrthoDB" id="2139939at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044688">
        <property type="entry name" value="SCI-1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117:SF1">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="40834" checksum="BCA78E2751DA7C0F" modified="2020-06-17" version="1">MSDHTHPSRRAFIRPRSLSRSRSPRRGSDHHDSHRRRSYHRDHNRSSAQKPRRSSPPPSRRFEPASLPCDAPVLSRKHDLERFRPVFALYLDIQKQLYIEELSERELKGRWKSFAEKWNRGELAEGWYDPATWVKAKEMIQSDIENDQHDATAHAGPSRGSLKRNKGGDQDDESSDEDEFGPAPLESRADSRRYGAAVPNMEELQERNELALQDKLAERDDLRYERKLDRKKQKERLEELAPRADPGTRERQLEKKREATETMRSYREAKSPGAEEVGERDLMGDDGVESYRASKKVEERKKNEREIRREEIMRARAELRQQKLAAHKEKEERTMEFLKELAKQRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPK5</accession>
    <name>A0A6A6NPK5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Complex III subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_355545</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPK5"/>
    <dbReference type="OrthoDB" id="6683853at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.210:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004205">
        <property type="entry name" value="Cyt_bc1_su8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119:SF2">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02939">
        <property type="entry name" value="UcrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="94" mass="10643" checksum="41FDB531DE924315" modified="2020-06-17" version="1">MGGPPTTGRYMGWWGHIGSMPQKGVVTYALSPNRQRPTAGMMHAAVFNTFRRFRQQVLFFVPPLFVAYEVMTWASERNEYLNSKAGRAEAGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPY7</accession>
    <name>A0A6A6NPY7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_292432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPY7"/>
    <dbReference type="OrthoDB" id="5402307at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="285" mass="29759" checksum="BD145E44D998EF98" modified="2020-06-17" version="1">MSLAYGELPPPPPGAALGDAGNANTDAGGELELRAKANRLQALLDEANCLQHSATATIDALQRNPDALAAVALTLAEISNLAAKLAPGALAALKGSFPAVVALLASPQFMIAAGVGVGVTIVALGGYKIVKRIRERKEEGMLEAPFAGGAGAPGPANDDGMDEDELRELDADMARVEMWRRGIADVQARSVGTTVDGEFVTPHASRMLVAEGALSEGDFRRKKGDAGEGGSGSGKKKGGKKEKEKERKGTRARTAKSARSERSGREREAGKRKRKEQSALRALFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ41</accession>
    <name>A0A6A6NQ41_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_366795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ41"/>
    <dbReference type="OrthoDB" id="3939134at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="28580" checksum="84AD90EF18DCCE65" modified="2020-06-17" version="1">MTEAMRPGRFAALTNFVIAYQSTNKIISLERVSNWEEKGDPTKGFAKPVRNEIIAQLKKIVPEFRRASKELLRHKQRKYEHAAERQRREREAILEAKAAEKAKRKNKWYALHVERLDVEPDPRRLGHLRMTERRHVDVDANGLPFERVAVFCPRNSRAYPLLNAEMQAEWSDEEKAALIDGLREYEGPEVFECIFQKYCRPGGPLRPYSVLQITTQAARLRKYFVGDNTADHGIESWMLNIPTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQQ7</accession>
    <name>A0A6A6NQQ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Carbonic anhydrase</fullName>
            <ecNumber evidence="4 9">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_366620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="4 9"/>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQQ7"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025719346" description="Carbonic anhydrase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="10">
        <location>
            <begin position="40"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="309" mass="33284" checksum="D07B23195B9A6988" modified="2020-06-17" version="1">MFYSTISILVGIAAFVDASCMHATSKLQRRVTPEGGVEVSTFGYTDLIGPLNWAALDAENSACTTGTVQSPINIDETIPITSEAPIINFPSVESAEFENLGSTVEVIVNGTTQFAGVDFELKQFHFHTPSEHRIHEEYYPLEMHMVHEAADGSGAVAVLAIVFDLSTDGSTTDLLTRVTEHLDEIATPGTVTETAALDFEELAHHLTTTPLFQYTGSLTTPPCAEGITFLLTEEPLPIDVATYNALKSVIKFNSRFTQNKLGNGNLLLLENNLQLGIETNAIHPSLAEAHEDPVMDAALALMSAIAAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRD7</accession>
    <name>A0A6A6NRD7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_374209</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RING-box family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRD7"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000111">
        <property type="entry name" value="Anaphase-promoting complex subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2454301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="92" mass="10620" checksum="16F319BBFFFED906" modified="2020-06-17" version="1">MKVVIEQWHAVAAWQWDMPEDDMCGICRNPYDSTCSKCKFPGDDCPLLMGECNHSFHMHCIYAWLQQDSSQDKCPMCRQAFKPKDAASTELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRJ8</accession>
    <name>A0A6A6NRJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphoribosyl transferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_373996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRJ8"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004631">
        <property type="term" value="F:phosphomevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005919">
        <property type="entry name" value="Pmev_kin_anim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF25">
        <property type="entry name" value="PHOSPHOMEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04275">
        <property type="entry name" value="P-mevalo_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="312"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="906"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="908"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1160" mass="126748" checksum="F8936727CAA2EA7A" modified="2020-06-17" version="1">MATLESLKRALRQKANATTSSPKQPLSDTQYSAGFEILARDSGWTTYQDFIIPQLSQLLIPLFNSRIDISVLEIGPGPKSLLGFLPDRLRQKVRKYTAFEPNGLFATRLEEWLCSTCETESPLPCMQDPPDIHRIPFVLQDNIESGASTSTKDNDEKYDIILFCHSMYGMKPKRRFIERALELLVEWPQGGMVVVFHRDGALRLDGLVCHRTASFPTGVVCIADNDEVLDSFAPFVAGFVMQDMDVDNAIRVDWRKECRALGRREEAHSDHLLFSSPNIMAAFTQHATTLPELTAQVTLVKGDETVKNREARLHRPASIIRPTEVQQVQQCVRWALKHGVGLTVVGGGHSDHCLWPNVLSVDMGAFDQVNILTAGEDVGDSDSGSGPLVVAEAGCKTGDIIHKTMAAGVTVPLGARPSVGAGLWLQGGIGHLARLHGLACDAIVGAIMVSVDSGQILCVGRVPRPHRPAGVVRPENEQDLLWAMKGAGTNFGIVVSVTFKAYAAPTYLTRNWVVPLSDNLEARLRLRDFDNLVGRKLPQNCSADAYLYWDAGQLHLGVAMFESTTKLNFTTPAHAPVDAIWGLGDGFKAVDGVGLFETEMYVSRMHGGHGGGKTSSFKRCIFLKRIGEANIVDRLVAAVETRPSPLCYLHLLQGGGAVGNVAADATAFGCRDWDFACVVTGVWPRDQDGTEAARSAVRWVYNVVGDLLSLSSGAYGADLGPDPRDAALAAKAFGPNRPRLARLKHSLDPHNVLAFACPLPKAPMQPKLIILVTGESCTGKDYCADVWASVFIRCTQKSLTVRAVSISDATKREYAEATGADLSRLLWDRVYKEQHRPALTAFFQGQVRRRPRLPEEHFLNVVYAAVDVDVLLISGMRDVAPVAALSHLVPDSRLLEVHVRASKQTRQIRRECHGGDDDGDDNKDSNDSRSKLTDSDYRPSLIFDNDAAGNEAAKRFAEHYLLPLFHEDLERLANMVRPVPDFPRPGIEFRHVLGISQQPGGLALCTSLLQTHFTGDWAKVHAVACCEVGGFVYASALASRVDVPLVLIREAGKLPPPTVSVIKSPSYVSSSASNSSKEKRIEIERNVVPRGKSLVVVDDVFSTGETLCAVLKLLDEAGIGLEDVSIMTVAEFPVHRGRELLRQRGFGRINIQSLLVFGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRK7</accession>
    <name>A0A6A6NRK7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_102730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRK7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="8850" checksum="833414C3EC9308C0" modified="2020-06-17" version="1">MTRCNDRICFALQPSLCLFGVIVSTAWTSRATWSSHKVNNCNSRDTCCCPNVELLGNHAHTDGLVRDIVYPPTPSLKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRL2</accession>
    <name>A0A6A6NRL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_387549</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRL2"/>
    <dbReference type="OrthoDB" id="648285at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000119">
        <property type="entry name" value="MFS monosaccharide transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF73">
        <property type="entry name" value="METABOLITE TRANSPORT PROTEIN YDL199C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="629"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="222"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="704"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="772" mass="84732" checksum="C22C369B18F108F8" modified="2020-06-17" version="1">MSGTVALPPGRGGCRRADDPRRFLGLPVWVARGSSPPTTVKIPSSSARRPANIPLHTLSSSHRHSRSHSHGRASNDSPDADAGPLLDSEKRGSGRSSFDSEAAASDFSLWSDTGDLVDQLGDAEDDPLRARLRESIEGDGHHPKHRHNHSRRVHYREEDLHPSREKEEGQPAVPKRKEDIPIPNPSRRPVSKGHRVLAIIMAPRDGPSRIHGLHGKKLIYFTSVFVSLGVFLFGYDQGVMSGIITGAYFKDYFEQPTRAEIGTMVAILEIGALISSLAVGRIGDLIGRRRTILYGSIVFVLGGAFQTFASGMPMMLVGRIVAGLGVGVLSTIVPVYQSEISPPHNRGKLACIEFTGNITGYAASVWVDYFCSYIPNNWAWRVPLLMQCIIGALLGLGSLLICESPRWLLDNDHDEEGIVVIANLYGKGDIHNPKARDEYREIKMNVLLQRQEGERSYTDMFKRYYKRVFIAMSAQSLAQLNGINVISYYAPLVFEQAGWVGRDAILMTGINAITYLLSTIPPWYLVDKWGRRVILLSGAVAMIISLSAISYFIYIELSWTPNAVVIFVMIYNAAFGASWGPIPWLYPPEILPLSIRAKGASLSTAANWAFNWLVGEMTPILQELIQWRLYLLHAFFCALSFVVVWFIYPETANVRLEDMNSLFGDATSVAPTPATLAEAESLFSGRGSPVPSLDIHRQPIGADNAIPGLNINPPVDGGAVEEGSSKRGKDGGEGGSEGLGGWISNLVKRNKGGEGDSQSGKYRRVDQDEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP4</accession>
    <name>A0A6A6NRP4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_374023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRP4"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="239"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="583"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="491"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="689"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="510"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="702"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="739" mass="76233" checksum="059B10FFC693FBBD" modified="2020-06-17" version="1">MSSSISPARTARRSVLQRHHHCRYHHAPPTTLARRRAAAPAAARAAAPAAASPQARASYLCLYSLRRALFSASPPRGLDAGDDDGGGVGGASGGQYRRSDFTTQGYTGIYEPGAPTAGPLGGASNVGAPRLTPRALKEHLDAFVVGQERAKKVLSVAVYNHYQRILELERQEDEKRERAAQRARAEMGHRHPVEDEFPGQQPTVTVYPAGYEPPPQPPPSPSPKLGNAPLTDTTALSIDKSNVLLLGPSGVGKTLMAKTLARVLEVPFSMTDCTPLTQAGYIGEDADVCVQRLLAAANYDVAKAERGIVCLDEIDKIATAKVAHGKDVGGEGVQQALLKIIEGTTLQIQAKQERGAAGGSGGGGGGGGGGPGARSGGAGGGAPGGASGPGGYPGSANGGGMGGMGMGGGVPPGGGQQRPETFNVRTDNILFICTGAFNGLHKLILDRVSKGSIGFGAPVRSARPVSAGEGVHETLLEESEAEALRRYLPYYEPTDQERRERSSGAGSGAEGSATAGPYAAAPSSSSGQQRPSSARPAPASPPPTSRQTPFNTLDLVQPSDLQTYGLIPELVGRLPVTCALSALPPDLLVRVLTEPRHSLLQQYAHLLALSGVELRVTTPALHALAAEAAAMGTGARGLRTVLERVLADAMFEAPGSGVKVVLVDARAARRERGAVFLGRGERGRLRGLVEGEEEEWERGREGAGPGGGGGDGGGGTGGDGGPIRSFEEYRQRWSAAGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSE4</accession>
    <name>A0A6A6NSE4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_352318</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSE4"/>
    <dbReference type="OrthoDB" id="1723750at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="38813" checksum="54ACC881FEF90F0D" modified="2020-06-17" version="1">MAGQFRFGFSGDEMGEADVDAGESHAGSGTGQMSSLEQAQSVPAQAHNVAEWLSSFPSRISYSTIKIESPKGRCLDVPRRELFDVKMQLLAEDEGNDADLLAGLDSADIKTNVYEGGFKSWECSIDLAALLLDRGPRKDIDDLCRVDHVVELGCGTAIPTLILYQYALSEGLSLYFTLADYNVAVLRLVTLPNLLLMWAKSLKSSTASPFSSENPNPLHESPTGDLEITPQICASFLESLREQNLILNLVSGSWTPPTAFLPLIPVSQDMNTLVLASETIYSPSSLSAFTEVLVGILERVRMGKAMVAAKRVYFGVGGSVSAFKQEAAGRKAVAYEIENADIIGRNGVQRCLMEVQMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSU4</accession>
    <name>A0A6A6NSU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium/calcium exchanger protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_94638</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSU4"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF0">
        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="872"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="899"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="933"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="963"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="995"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1046"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1083"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="123"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="937"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="414"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="496"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="712"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="763"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="812"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="512"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="736"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1111" mass="121178" checksum="0315BFD0D9D4AB8E" modified="2020-06-17" version="1">MADHVVARTRHRAAKRQRQKYSARPFYLTILVISIIAVLAILRDRSSGVAGSDLSSSGLLRRDVGLLQDGEDEECRHVHKAVDKCAFVHANCPDEEAGIISYLSLYYCRLPHAKALAFVILILWLALLFSTIGIAASDFFSVNLSTIASLLGMSESLAGVTFLAFGNGSPDVFSTFAAMSTNSGSLAVGELIGAASFITAVVAGSMALVRPFQVARRSFIRDVCFFTAAAGFSLVFLWDGALYLWECVAMVGFYLFYVVFVVVWHWWLTRRRRWRQIDVTSRSHFVVPGGEEADMPEYHDEDEDGSAGTHTRTQSRGVSQDDFAALEMGGDGAEEDELEEEEARGRWMSELSNNMRLSRPRSRARRLTKTPIRPSLVGALEFRAVLTSLQKSRNIQSQPIYLRRYSDDPNFTTAQQQDRLSTFSDPASSRPSFDVSLGPDSTSLSVSRPSLDARDGPHRVRAVSANGADALRIDHDAMRRPNVPQIDLLAPLAEDRSITHDQSSTRRSSLVPPSPTISLSPPPSQTSRASSPAPSSARALSPNRLAPPSDPNHPNPQHRDHHGRIDGQADSREAVASTATRSGAPKAPKLQIPSSAARAPQQSGHSPVSPFPAYTDYPLSASTASRAPSIRLPSPSMSPESYYGDTLLGHDEPRPPKWWPLTMLPPPQVLFSTLFPTLYTWKDKNTWERFLAIVAAPSIFLLTITLPVVETQKDEEDEEDGDDGTTAVPELSLPGPASPVPPSQPQKRPPQNAATVRILIDDDGQPTESSTLMNGHGDNHAAPHAAIEHNLSPSRGRRRSVDYGTIDVATAAEDVHRQRFHSGGPGVTTHGPPQQAPQRQRPRPQPQISASPEQLPAAGTPKAVEPKQWNRWLVMLQTFTAPLFIVVIVWANMHPTEPYLLVKPVLVALVVSLVVLALLIGTTTATRPPRWRPLLCFVGFAVSITWISTIANEVVGVLKTLGVVLNISDAILGLTIFAVGNSLGDFVADITVARLGYPIMALSACFGGPMLNILIGIGVSGCYMTIKGAKHKQEKHPDRPMKFKPYHIDVSSTLMISGATLMVTLVGLLIVVPWRKWRMDRQIGWGLVVLWAVSTIANVILEICGVGVDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT56</accession>
    <name>A0A6A6NT56_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT56"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="17587" checksum="4E046DB38EF20348" modified="2020-06-17" version="1">MYLGMYHYGVLLARMPSDPFFAQELAVWRCRSYLRPLISVPRWSPSDNAAGNRTYPMIRRATVVLFVVSNNTTHGPQLHLARERVHGATPLPTALPCCRLTGDVFRPLYVVGTASQLPVCTLPARSTKVVRRISEHRQRLHRHDKPRPSFSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTI3</accession>
    <name>A0A6A6NTI3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_366139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTI3"/>
    <dbReference type="OrthoDB" id="4932428at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="192" mass="22145" checksum="C44BFBD26E938076" modified="2020-06-17" version="1">MSVYSTSSVDSEYSNPPARQYSLPTFDIMTDGSLNEHEKEQLIHSLRTHRLNTLVELRRVEKIFARLGSQDLSEPMTTAWAYYVNSHTLLTELRSLTRNYPFSSDCLDEAKRRVYTDPTSNRSWNLCWLVLVKMQSDRLIPYYAQHQASQPSMWGNRIPSAEGVAQLTNAFVGEWEGAVDQLLRNWDVPPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTJ6</accession>
    <name>A0A6A6NTJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPR1/FUN34/yaaH family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_351077</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTJ6"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="267" mass="28514" checksum="E31A799814138265" modified="2020-06-17" version="1">MGSDEALRQIRTAGSISISPELFEKLYLSPQNQVKGDLRKTFGNPTPLALLGFLLSLSPLSCDLMGWRGAGGAGASGTATYMFFGGVLMLLGGVGEWILGNTFPFVVFCSFGAFWLGFGGTLQPFFNAYGAYSTDPNNPAEGLNEVGFNSGLAFFLLAMGLLCFVYFICALRTNVVFVLIFFTLVIVFCILAGAYWQTSNGNTALASRLQIAGGAVAFVTCACGWWIFVAIMLAALDFPFQVPVGDLSSVIKGASERQREKAVTSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU25</accession>
    <name>A0A6A6NU25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_373380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU25"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11854">
        <property type="entry name" value="SH3_Fus1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035521">
        <property type="entry name" value="Fus1_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="453"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="403"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="505"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="110"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="645"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="718" mass="74293" checksum="D1B20BDAC8EC6976" modified="2020-06-17" version="1">MHGHHRLAHRQPAELVQPIEAREAEAEPQETVVSVVYVTAPQTFDGPAVYVTAGEPVQFTRSSSARTTDRETERTTEARARPTTTRGDDNSDDEDEDEDENEDEDRSSRSSRASSRASRTTLATSRRTSTVSSSERETTTITSRSQITSTRASASTAQSNVLADTASTSTQSAQASDVDAQPTGMTAGAKAGLALGLLLAVAAVLGLVLLYYRKKKREQQAQHQKLDDEKSAMPPPPPPASAPEVSSAASIRTARTASTAPRLSLRPVTQFSPTFGENRKSSGNLLNVAAAGAANNGSRSPSPAEKNVSEKNMPEKKNNVNDPANPFGIHAETIDNNEPRGQSPGAQASNGSPRSPPPGDLPAPTMPAENAHDSLAIATGAVPLGAAGAGANNSTASLNTPSMASTMVAPGPPSPAFTDSAFTDSGDVPPSPGPAPTGPVPLVAGAPAHGPAGPNNVHRVQLDFKPSMDDELELRAGQLIRVLHEYDDGWALCIRMDRSQQGVVPRTCLSKHPVKPRPTNGSPQNRGPPRMRGPPPMNGAGAGPNAPFAQPPRPLSPSGRNSPGPLGPRQPRPMSPAGGPRPMSPAGGRSSPVPFNGPRPMSPASERNSPGLFAGPGPRPMSPANGNRGRSMSQGGAAGGPPPFAQGARGPRSMSPGPYGGGGYQRPPPIRENKRRSNSASEVMARRASPPGPSPLNASAHKAAGGVPARKPVPGQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU27</accession>
    <name>A0A6A6NU27_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_72556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU27"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="85" mass="9183" checksum="9E415F813C9A6548" modified="2020-06-17" version="1">MPPPSLHATQAQSHQENYKGPIAFSVCIFPSTSSHQPAMETTPPQATPCSMPKARATMKKETPNPKEKGEGKGDQGEKRGKEPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU37</accession>
    <name>A0A6A6NU37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_350343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU37"/>
    <dbReference type="OrthoDB" id="2365484at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="135" mass="15475" checksum="A8DABE60CB992AFE" modified="2020-06-17" version="1">MKFLKVGRVAIITRGRYAGKKVVIIQPVDTGNKAHPFAHALVAGIDRYPEKVTRRMGKARVAKRSKVKPFIKAVNYNHLMPTRYTLELEGLKGAVSNDTFKEVAQREEAKKSVKKALEERYQSGKNRWFFTPLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU47</accession>
    <name>A0A6A6NU47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_307361</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU47"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016817">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000010">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000332">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013967">
        <property type="entry name" value="Rad54_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08658">
        <property type="entry name" value="Rad54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="238"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="571"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2455266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="814" mass="91643" checksum="69A5E327E938E9C4" modified="2020-06-17" version="1">MHRARTIATSDGSDSRSSVGGLAARLYGGSPTSADRLVRPFKCPGSAAPRRSSEKPARKRRKVNYTGADGDAEDSDKPYTNDDRLALATRDVNRFPVFRPKDKDTAFRRQFSVPLVNKENGAYDATRPPPLLGMRQGATFVAKPLHDPSGEFAIVLYDPTVDDKPPEEQKEDATNEPGPAPKLDEPLEHKSLADILGLKKKVQGERKRVPVVIDPRLAKVLRPHQVEGVKFLYRATTGMIDEKANGCIMADEMGLGKTLQCIALMWTLLRQSPDAGKSTIQKCVIACPSSLVRNWANELVKWLGKDAITPFAVDGKASKDEFVTQMRQWAIASGRAVVRPVLIISYETLRLNVEELRGTPIGLLLCDEGHRLKNGESQTFTALDSLNVQRRVILSGTPIQNDLSEYFSLLNFANPNYLGTRNDFRKKYELPILRGRDAAGTDADRKRGDECLSELLNLVNKFIIRRTNDILSKYLPIKYEHVVFCNLGPFQKDLYQHFLQSPEIKSLLRGKGSQPLKAIGMLKKLCNHPDLLDLPSDLPGSEEFFPEDFVPKDARGRDRDVKPWYSGKMMVLDRMLARIRADTNDKIVLISNYTQTLDIFDRLCRSRGYGCLRLDGTMTVNKRQKLVDRFNDPDGQEFVFLLSSKAGGCGLNLIGANRLVLFDPDWNPAADQQALARVWRDGQKKDCFVYRFIATGTIEEKIFQRQSHKQSLSYCVVDSAEDVERHFSLDSLRELFEYRPNTTSDTHDTFKCKRCKPDGRQHIKASAMLYGDTSTWNHFVNEGEKGPLNVIQDLLLRQETADKAVSAVFQYISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU83</accession>
    <name>A0A6A6NU83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nuclear pore protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_387180</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU83"/>
    <dbReference type="OrthoDB" id="5566198at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="389" mass="43046" checksum="4ABC35D9031405E1" modified="2020-06-17" version="1">MADPERGFQTFSHGHQDLVLAVDFNFYGTRMVTASSDQRLKVWDRNTKKGATEQWTLVDSWRAHDAEIVDVKWNGPLSGIHIGSISEDGRFRLWAEDVTETPNSSRRFKPIYQHYSETKVPFMSLDFKNQLADTILALVSRDGYLTIHEPSDPDRLTEWHCLTASYVYRAGNGGPDRQDETSFRVAWHKEPLPCWQAIAAGLDRRALSLAVAAMDTVRIYRTDHNRQFYVAAELPGHRGLVRDVAWANGSMRGYDLLATACKDGAIRVFELHASPQQQQPQQQPHGTSTTSLSTVGPTGSAYSALGSPHIQHPLAGGAGVEAGPGRIIHNVRPMAELVGHHGAVWRVAFSQAGDLLVSTGDDGAIRTWKKSHTGQWLEYAEIGAGRADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUD1</accession>
    <name>A0A6A6NUD1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL15</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_365558</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUD1"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="8">
        <location>
            <begin position="72"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00080124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="149" mass="16793" checksum="0FABAE252B380FA5" modified="2020-06-17" version="1">MPTRLTKTRKHRGHVSAGHGRIGKHRKHPGGRGMAGGQHHHRTNLDKYHPGYFGKVGMRYFHKLQNQFWKPTINLDKLWSLVPSETRTAYLAGEKKDTAPVLDLLPLGYAKVLGKGRIPEIPIVVRARYFSKEAERKIKESGGAVQLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUN6</accession>
    <name>A0A6A6NUN6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_289948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUN6"/>
    <dbReference type="OrthoDB" id="3792540at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF1">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="149"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="408" mass="46529" checksum="F1C517F8C1D09B3F" modified="2020-06-17" version="1">MAYTRDADGFAVPPTPDSYAGSIAPSIAPSDDTGATPGSSRSSRGVEDSSYRDQNLAFNHVYMRERYEQFPEHVSSLVDHVRRDRESPGPSPDEVWQDMDLTALETKGLDEPEVEDYFRDRVFPKPKQGDDLRRSDRQPMSRYAVPNAGPQFKVSNPFPDMLYGYSRHHAFPNQQTQLISMGNEMNGTANSQSLMYPFFVIEFKGNGGDLWVATNQCLGASTSCINIAERLNDQLRKCKSSKVKPVDSTAFSIAMNGEVARLYVSWKHSDLDYYMQKVDNFLLQKPQDYIEFRKHVKNIIDWGKDTRLKEIRESLDTLLEESRKRTSETAKSRPPPTKDSTSRSKRHKPPPSRKSSSSGHDTKQARSEPEDQYWQWSETAGQYYHVHSDRTIEWAPPTQQSPHPESDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUT0</accession>
    <name>A0A6A6NUT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_373180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUT0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="76" mass="8706" checksum="9ED4A6333F7C40C7" modified="2020-06-17" version="1">MTSENLTEPVTECKWRTVTRNDGTKYRQKYHDCWSRYCKWSANYVPSSDEFLSSPPDPAEREDGGGTNRNQDGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWD6</accession>
    <name>A0A6A6NWD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_348679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWD6"/>
    <dbReference type="OrthoDB" id="8300194at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="32726" checksum="5C30687B883B3508" modified="2020-06-17" version="1">MMPVPSQGSLDSSQEPRDARSGIQNSWFRRSFTLAAFALLRRWSPTDGRVFMLTPHLCLKCGPTRHISEAETMVYVANNTSVPVPKVYCAFRRKGITYILMERIEGNTIGSIWASASAQKKDRLRSQLRAFLQELRSLPPPRPGHIGDVNYSKLYDDRLSATGFGPFTTTKDFHRFLRRDVVITPGKLAELDQLISDHESREYETCFTHGDLNSYNILVRDGCVVGIIDWEMAGWYPKYWEYTSAWHVNPFALWWKQEVGNFLDTYPAELEMEKLRRKLFPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWF7</accession>
    <name>A0A6A6NWF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Enolase C-terminal domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_347955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWF7"/>
    <dbReference type="OrthoDB" id="2579025at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03325">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023592">
        <property type="entry name" value="Galactonate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010624">
        <property type="entry name" value="PRK14017.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080:SF2">
        <property type="entry name" value="D-GALACTONATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="D-GALACTONATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00003">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00908">
        <property type="entry name" value="MR_MLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="6">
        <location>
            <begin position="125"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="380" mass="42061" checksum="EEBA1BA7EE904E1A" modified="2020-06-17" version="1">MKISTIEYFRVPPRWLFVKITDEAENVGWGEASLEGHTEAVEGCLDAYRERFVGLEADEIENIWQNGYRVSFYRGGPVMMSALSGIDIALWDLKARKLNVPVYELLGGKVRTALKVYAWIGGDRPSDIEAHAKSRRMQGFKAIKMNATEDLGWVDSPSSLDSCVERVKAVKALGLDIGVDFHGRVHKPMAKQLAKLLEPERPLFIEEPLLSEHIEGIQSLSNLTTTPIALGERLHSRWDVKRFLEARCVDILQPDICHVGGISELRRIAQMAEAYDVALAPHCPLGPIALAANVQVDAVSANFAIQEMSLGIHYNAGAYDLTSYTKNPEVWNVEDGMIELLAGPGLGIEIDEEQVGAAAKDAKPWRGSEFKGPGGEIREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH8</accession>
    <name>A0A6A6NWH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_55383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="199" mass="21431" checksum="5A500B84CEF37B36" modified="2020-06-17" version="1">MVRAAVLDVSVLLPLYNVPTDPARNRPSAIGLTLVLGVSRTRPRPARPLCLFSLSHTHTLSLGSADHRHYRHYPPTHNQPEPPRPRDAPTTADGRAAVHRSTPRRSAGNAPRTRNAARLRGPCGVPSGREGRRIVAIAPFRTWAGAGWAGARIGPGSVGLAWLVYLGGRVGALKVGCGGRSCLSKPGSSLRRRSCVWWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWN2</accession>
    <name>A0A6A6NWN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Clasp N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_56524</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLASP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46159at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990023">
        <property type="term" value="C:mitotic spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060172">
        <property type="term" value="P:astral microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF9">
        <property type="entry name" value="CLIP-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="9">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="9">
        <location>
            <begin position="272"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="504"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="776"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1040"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1179"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="511"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="563"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="639"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="663"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="707"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="785"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="820"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="862"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="943"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="963"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1192"/>
            <end position="1207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1299" mass="140261" checksum="224AA68A7DD4AF65" modified="2020-06-17" version="1">MEEQAATLLATLRKSSITVDAKLAQFNSLKSNIKHQRVPDGAHVHIFECIRLGIGSQVSPSLVSAGFATLGHFIKRLSVQDQTHLVAAQAGKLLPLLLDRLGDSRESHRIAASQCLTDLWPIAQEQVERVVRDSALRGTNARAKEMAMTWLVKMNKAEGLQFRSYVPYLVACLEDPDAMVRETAKSTVVELFSNAPEHAKADLKKQMNNLNVRKSISQFIISHLGVPGAPEPDLKASTISANSTEFSNPDNAFGDSMMSEHPPPAETATMEPLYVHTQRELDDHFRDMLPHFEGKETEGNWIARDKSVFRLRRLTKGNAPSEFHTAFMAGIKSMLDGIIKVANSLRTTMSSNGCQLVQELARTVRSSLDPMTEILLQNFVKMTAATKHISAQNGNVTVDTIFSYVSYNARLLHHTWLAVQDKNVQPRTYATGWLKTIIKRHASHKSQIEHTGGVDIIEKCIKKSLADPNPKVRENSRSAFWVFHSVWLERASVIMNGLDAKSKANLEKDPNNPNKSLASSAPSASEPKATFSRSVGGPGASSRSTLREAIAAQKKQRAVQIERPNSAQSALSTSAEQSSGPPRAGTRPGGLAAPSGPVRPGGPTTGGSLMSGPIRRPRRPELARPATAEPFGHKRIPSKTDTLAETPSRQTPSNSPPKDLTSKRSTTLQKSATRGTTRPPSKIASPTTTSPVRSKSRVEQMRKTPLANRTMQESPGSSPSKDENLTMVVPFTRPPKDDEPVPFASVRRPAADKHMSVDSGIPSVSAEDEGFTMVLPNMKFPLPGKGEREQHQQQDDRPFRRAQMSPTKAAHSPRLGSPLVSPVRSMARSPRSPRSPERVAGTPPSHHPSRSIDSAMASASHQESEEVKVYEDPFTGGSPPGSRSVQRSGDDKPALEELPLNERAPPIGSGGSPTLSTGSHTLDHSVRPPSPSPQRPFPGHAKNGSTGSTNGAQNGGFMTVGGDRPDEQKRTEILKSRRLLSSGIERIRARSLDAHGFRRLQDLVKTAASMPEIWGENATTFGALLMALLDFLKMPLPSAAEAGDQPQSHIPVPSSTATPSSAHAKALNLRTQTLSTLRALLSLHRRLASSFLADPVLPSLLRARANADPASHFSVELDRVVDEVVRAANRDDALEAMLALLDSGAVAPESMSEADKEPLHPRTQVGALRALGALLSPNVGSHMTPASHLPRPSSGPGSAPGSVPGSPTKAPPLSPTKLHHAAASVQPLAQQQTARIGKSAVRLLGAPQPDVRQAVLEACLALHERVDGGQKDGFWRAVVGAKEGQLNLIMYYLARRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWU0</accession>
    <name>A0A6A6NWU0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Carnitine O-acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="16">2.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_288219</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA</text>
            <dbReference type="Rhea" id="RHEA:21136"/>
            <dbReference type="ChEBI" id="CHEBI:16347"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57589"/>
            <dbReference type="EC" id="2.3.1.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.7" evidence="16"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWU0"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000007">
        <property type="entry name" value="Carnitine O-acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 19 22" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 19 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="21">
        <location>
            <begin position="108"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00053195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00066910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00073438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2456028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="683" mass="77046" checksum="9438AAB4E5F9B1EA" modified="2020-06-17" version="1">MFNAVARAARSPAWSSSTSLLRRRSPQAASSQARPTTASAQHALADSTLRRSSPWRPPQSARAAPCRKVRPAPGAPAPPPAPALTLAGYREDPSKGAMLRFEDSLPRLPVPSLQETAQRYLKSVHPLLSAAEFEATTKAVDEFAAPGGAGETLQKRLVARREQPGVRNWIIDWWNEAAYLAVRDPVVPYVSYFYSHRDDRKRRDPAKRAAAMATAVLEFKKQVDGKTLEPEYMKKLPMAMSSYEWMFNACRKPAKPSDYPVKYPFQANEHLVVIRKNQFFKVPHAVNGKQLNTSELEKLFRRVYQMAEKSPPVGVLTTQNRDVWADVHARLLKAHPSNAAALETIESSSFVVCLDDATPVTLDERARQYWHGDGRNRWFDKPLQFIINDNGTSGFMGEHSMMDGTPTHRLNDYANAVIFGNKLDFDDASVRSNLPEPMPLRFTLDAQLEEDIRAAETHFEYQIGQHELRVQAYQGYGKGLIKQFRCSPDAYVQMIIQLAYRKMYGKNRPTYESAATRRFQQGRTETCRTVSDESVAFCDAMCDPAVPANECAELFRKALNAHVKYITDASDGRGVDRHLFGLKKLLKDGEELPSIYRDPAYTYSCTWYISSSQLSSEYFNGYGWSQVIDDGWGIAYMINENSIQFNVVSKHLGCERMSHYLNEAAGDIRDVMVPTMEKPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX45</accession>
    <name>A0A6A6NX45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alcohol dehydrogenase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_276765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX45"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="9993" checksum="65484C16061ADD22" modified="2020-06-17" version="1" fragment="single">SRKGGTVMQAGLGKEAMAFPIMAVCTKVLVVRGSIRYTAGCYPAAVELISQGKIDAKKSIMNRFKFEEAEKASELVKEGYDSRCTVKRTGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXC8</accession>
    <name>A0A6A6NXC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_364862</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXC8"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="63"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="213"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="52845" checksum="AB705DF28AAE8A3A" modified="2020-06-17" version="1">MSGGAAAVRARSSGMAALRSSPCLRSSYTAWRPRAADAIPRRTITPALAALARYYASKSFPPHTVISMPALSPTMQAGNIGAWQKKVGDSLNPGDVLVEIETDKAQMDFEFQEEGVLAKILRESGEKDVAIGSPIAVMVEEGEDVSAFSEFTIADAGGDKPPPSEKKEEKPEAPAEEAPSKDTAPSEPAPAISAQESASEGKPLEPSLDREPFVSYAAKKLALEKGVPISQIKGSGPGGIVTLKDVENFKPSAPAAAAGPAAASYEDVPASGMRKTIAARLTQSMRESPHYFVSSSMSVRKLLALRAALNAASNGEYKLSVNDFLVKAMARATTKVPAANASWREDTPGQPYVRMHSACDVSVAVATPAGLMTPIVKNVGGLGLQGISAAVKDLGARARAGKLKPEEYQGGTITISNMGMNDAVERFTAVINPPHASILAVGTVKKVAVPAEAEAEDGEARVEWDDQIVITASFDHRVVDGAVGGEFMREVKMVVENPLELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF3</accession>
    <name>A0A6A6NXF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_57914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXF3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="29595" checksum="3C173779B7E6645D" modified="2020-06-17" version="1">MNEWRPEQGPRKPFGTPSGRAGIQNQPWQAYQGRRIARSRTTRAPRSGSNHRPSIAGDPPGFKRASAQQSWGGRNWTHNARAAILIASANPGGEHSVPISLPSLQRRCKSIIRTYSIVWPGGSDYTRLLLTYLASLPGSNCFLFCEPMYPSTITQVTSLAYYPTLPSPFPPLPKPKECHLSLHLTDDRLRVQGHQFSWCLRKQSSGDRPVQFRNQRMMRPHSKRKQQVCDPGNREKTSLFFSPFICRLQVEIVFLVFSFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXF7</accession>
    <name>A0A6A6NXF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_50143</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="4"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXF7"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF113">
        <property type="entry name" value="POLY(A) RNA POLYMERASE CID11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="10">
        <location>
            <begin position="173"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="9">
        <location>
            <begin position="393"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="499"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="606"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="685"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="830"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="947"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="535"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="606"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="638"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="685"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="721"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="844"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="869"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="964"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="997"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1012"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1059"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1077"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1098"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1121"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1155"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1191"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1231"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1250" mass="134997" checksum="5DEAA060108F8A8C" modified="2020-06-17" version="1">MGVPTGTPPMVARTNRNSPGVADGGGSNSNGGGTANSNSGARREGGGGATNSCSGSSSGGLSSQSTPFRPPMTSHHSNSVPSTPHQYPRDLAFRSRSRSPSPAGLGSHSPRSVTSEANGVMPTLPGKPRQGCRFETNVAFGRRRMRYDIGADILPKAEKEPKKTLEPHEADKLSGDMRELYDRLLPSDDSQQRRKKLVEKLHRVLITEWPGNEFKVHVFGSSGNMLCTSESDVDVCIQTPMKKLETMHMLAEALSKHGMDRVVCVSSAKVPIVKIWDPELKLSCDMNVNNTLALENTRMIKTYVQIDDRVRPLAMIVKYWTKRRILNDAAFGGTISSYTWICMILNFLQTRNPPVIPALHQMPHKKPPDGEPDLSFADDLETLRGYGNENKESLGELLFQFFRRYAHELDYETHVISVRHGRLLSRKEKGWDISSLTKEGRDRLCVEEPFNTSRNLGNSADDTAWRGIHLELRRAFDLIVDGLQLDKCCEQYEYPPEENKGIFKKPASGPKPVLSQSLPHSRGRGGGGAGRGGRNYNQKSAHGSRRASSGETFLNRHQFAPSPPIQVGGADYFGRGGSSNIHELYYRYQLIDMQIRERLLQQSQQQAQAQAAHTHSAHMQAAQAHAQAVAQHAQAQARGTQMSNSPQRTPYVNGQPSPGLLEHPPATAPLMYGNLYNYQAHFEPSQTQSMAPSLSQEGSRTNPSSPSLSSPAPSLRRTAHRSSVTNGTQSSSIRSQSQPARVASNPLVQGAFAVPYQYDPATGAVSGYPMVPYPDFSQGHGQGGVELPGFTLAAPGMDHGVPKEYVGYYENSPQMPQRPDFQVPAIPIFKELPQQRRRRVSPEHMQSLNRMPGANKSSRSPSPLGGRLRSQSTGLQSTPLAGRQQQLDPTSLPGNSGLLIVNGSLQHESHQQQQRVPMEQQQQFAYPQDPYLVPSGLGQSVELSAMPMNDENQRPPQFGPVVADSNSATAFGSPSRIASNTSTKSVDYASPKIVPSSMATASELSPKTTLTQQQPQQQQQQQQQQQRHASPPLKTTNMSPLDISMGPNSGSAGLQPKDTSSAPTTTTASSAPLLSPINETQTPSPTASRRFSKEVPTSAAQQSQPPQQQQQQAPPKPVVVNGSTAVVNGRSTSAYRDEMPAPPTPASASSDGAKNCQQPSKGSVTPATAVSNKGGAKAAPKKDGSEQLPVSGTSTAASSPGASSGAGAGANVWQQPKKARNRKGGRSSAANERKREGEPMPANEADRKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXT4</accession>
    <name>A0A6A6NXT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative eukaryotic translation initiation factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_386388</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXT4"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000031">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="275"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="438" mass="48329" checksum="EE8DBDEB97747502" modified="2020-06-17" version="1">MSFINIPRDVSDPFYRYKMERLLSKIEGKGNGIKTVVANLPSVSTSLARPPSYVIKYFGFELGAQTNNNPADDRWIINGAHDSGKLQDQLDGFISKFVLCKKCRNPETDLQCKDGHIFMDCKACGQRSEVDPRSKLSSFILKNQPKKSKKDKSTKKADRKARRQAGKNGEADNHANGDADGDEDARNGGSPGGGDSGSDAANGSGDVEIEAGSDDELTRRINASAREIDADADDAKEVQWSVDTSEEAVKARAKELPDDLKRALVVDDDEEGENGEGGRSAYDELGSWILNVAEEKGGVANVQDVEIFLKAKELGVENKHRTLTVLAQTVFDDGIVKQIEGRKAMLKKMITSEKHEKALLGGTERFVGKQKPNLIPQVSVILMKYYENDLVSEEVLKSWGAKASKKYVDLQTSRKVRKSAEKFMTWLEEADEESSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXX2</accession>
    <name>A0A6A6NXX2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Solute carrier family 35 member SLC35F1/F2/F6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_346923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXX2"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="44933" checksum="D51F916EE056CF1D" modified="2020-06-17" version="1">MTVDTTHVRPKSGEADASPLSALDSSGSGSNGCAVAGSEAAHGRAELVGADVTMADAVAAEGANEKRGKRLFSYVKTKQFWIVLLLGQVLALCITSTNTFSSLLAGKGTNIPAFQTFFNYVLLNIIYTSYTIYKYGFKKWGKLLLKDGWRYFILAFMDVEGNYFVVLAYRYTTILSAQLINFWAIVIVVIVSLIFLKVRYHLTQYAGILVCCGGMGLLLASDHITGSNGGTAANQLKGDLFALLGATFYGLSNCLEEFLVSKRPLYEVIGQLAFWAMLINGTQAGIFDRDSFRRATWDADVGGYLVGFTLILALFYSLAPLVFRMASAAFFNISLLTANFWGVVVGVHVFHLSVHWMYPVAFVLIVAGLVVYFATETVLGEAKKPWLGENQERGIAGLGTAKRRVQKPDAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY90</accession>
    <name>A0A6A6NY90_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_347400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY90"/>
    <dbReference type="OrthoDB" id="5043642at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="317" mass="37082" checksum="148547E15382CDB2" modified="2020-06-17" version="1">MSLTRLEPDWWLELERSYAQRVAQRQELFQKHGKMVLDALPGSELACKELMEMCLQFYAARYPGLFRIDKENMVFHNGILGTKTDLKATSPLHVLLNNVPEDFGIMLRDPQDGSYQFRAGTICSSLGWHVGTKIGMRLHEIHEPIPDYKEKMQFSMDRYFAKKPTDKAIQRGSWGLEVDQPLFMPPGDPHEKYRDYQASELTLSRCNLRVDWQTLRRLPLSAAVVFNFKGLFTPVEEFADEPYVPSIVLKVLREGKKSIMEYKNTWHVEHVVIPALEKFEKEQVEKGMVEKDWNVHTLDESPFFPGWEEKWHRMQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYL6</accession>
    <name>A0A6A6NYL6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ornithine decarboxylase</fullName>
            <ecNumber evidence="10">4.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_287280</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-ornithine + H(+) = putrescine + CO2</text>
            <dbReference type="Rhea" id="RHEA:22964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="4.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer. Only the dimer is catalytically active, as the active sites are constructed of residues from both monomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.17" evidence="10"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYL6"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00622">
        <property type="entry name" value="PLPDE_III_ODC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.37.10:FF:000010">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000005">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6 15" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="16">
        <location>
            <begin position="68"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="15">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2456644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="447" mass="49451" checksum="E26CEE02D403F909" modified="2020-06-17" version="1">MAPSAISRHDEYAPLSFKNWQPVDGWYDHHGSLDAQGLIGDALLERVEDIDQDVCEAGDEDAFFVADLGDVYRQHVRWKLNLSRVTPHYAVKCNPDPQVLRLLAELGTGFDCASKSEIEQVLNMGVDPSRIIYAQPCKTKSYVRYAAQKGVKQMTFDNADELYKTKQLFPDAELFLRILTDDSASLCRLSLKFGASLDSTKGLLELAKKLDLNVVGVAFHVGSGASDPKAFLQAVKDARTVFDQAAEVGYDLSVLDVGGGFCSDTFEAMAAVLSSALDHHFPPHVRVIGEPGRYYVSSAFTLACHVIARRTVCNPGEEGKSYMLYLNDGVYGNFSSIMFDHQQPTPRILKAGERFLHGRRPDGAYDPLAEHGGKLTEYSIWGPTCDGIDCISARSKFAETIDVGDWLYFEDMGAYTKCSATRFNGFTDNHEVVYICSEMRARAILGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYS2</accession>
    <name>A0A6A6NYS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_393710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYS2"/>
    <dbReference type="OrthoDB" id="3540210at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="573"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="699" mass="77000" checksum="D57E3396FFA70A82" modified="2020-06-17" version="1">MAERAKDVYVGAWVDWGKGAISGATITVPSAYGAILVAFLALYVRLAGSHFWNIVCFFTHQLRSAPHLEQDGLYHQQQAVLRGGLDDTAVLWQLAKLAWCWKDSTRRIFRRSVPLGLAAGAHALGFAAAGLFSSRVASATDLVLVRSPLCGWMDEPLDVHDFPAMAEIDVAGALLVAGRWSYDDALEYARSCYGAKPTLNSVLCSTHAKVRLEYETGGKPCPFADGACGSSHALFMDSGLVDSDLDLGINAPPGDRIKCRKTMTCAPIPADERYAGNWTLTPPPSVLITHFGNQYRSYYMGPYNGYLVRNETAILSNYSLALGTGPYELSAMSGYAVDESKNVFSPIDDLKQDDADVTILMLVNRVVYTQEVTDPWFRSARKFEVDGVPGIGYLGPFYAASQSLGVLGCTEQYQFCNGDRCSPLTGIFGLKPPEVLTSENGSFSSGSSSSTFLDFNTKQAATYALVWKAIWGAQVQYAANLLKDRVLVARDLLFGSSRMSSPVRDRQWEAEARNLFNVSLVMLQRRVVEYAAPPVVDFEPDVPASDYVVAPNTTAGRRLCATQKVRSNAYDSFSVLGLAIIVVGGGLIMILNTFLTELVGWVQRRWRRPNDAYRRLEWIESETLQLQRMAFEGRGVGPWRGKEDAVPVTVTFEQRFPFPGSAQLGSNEPNVDEELQAMYRKKRKGEELEHDDARVTSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYV0</accession>
    <name>A0A6A6NYV0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidophosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_346342</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYV0"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="629" mass="68158" checksum="311C3B0236EE4B61" modified="2020-06-17" version="1">MCGIIAVIHGDPHSNSAAVEIHDGLYLLQHRGQDACGIVTSLNTGRVYQCKGNGMASRVFHDGARVADLPGFMGLGHLRYPTAGTSANSEAQPFYVNSPYGISFTHNGNLINAPELRRFLDHEAHRHINTESDSELMLNVFASELNETGKARVNSSDCFAALERMYQRCVGGWACTAMIAGFGLIGFRDQYGIRPMVVGSKPSESGHGMDYMMASESVALVQCGYKNFSDLLPGQAVIIEKGKEPVFCQVAKQLAYAPDIFEYVYFARPDTVIDGIDVDESRRNMGFKLADTIRKQLGPETMQEIDVVMPIPETSITSALCVAESLGKPYCQGFVKNRYVFRTFIMPNQKQRQKGVRAKLNPMRKKFEGKNVLLVDDSIVRGTTSREIVLMAREAGAKKVFFTSCAPPITNAHIYGIDLASASELIAHHRSSADIARVIGADAVIYQTLPDLEAACAALSPRSPEHQRFEVGVFCGRYVTPVAEDYFDHLERIRGESRKLKVMEKAREAVMQGVAGEKEVRMAAKGVAVDRHGNVIPADEGIANGAVAFGAQMSNGALGLGHQGGAMEGGGVGGTVHCAVKGKVNGNAEGGEAVDGSIQDRLSREGSEPHLRVRDSQDISLHNINDHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ94</accession>
    <name>A0A6A6NZ94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_422038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ94"/>
    <dbReference type="OrthoDB" id="3777149at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="18146" checksum="502D2A55959EF7B8" modified="2020-06-17" version="1">MFLGLLIGFLFCFVSGLLLDVVLLFNNASWLKKNKHKRFWERTVDLLFSICQAGLSIAGIVAITIAFITDTEPHWLDPVILCTLQLIAGANHTLLSHVAIASVWSWTLWNEALQKHLRSGNSIPERVRTLRRLSLANVRTSEIRQGIILSYIDRLVCSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZQ4</accession>
    <name>A0A6A6NZQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein hob3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_364133</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZQ4"/>
    <dbReference type="OrthoDB" id="446293at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07591">
        <property type="entry name" value="BAR_Rvs161p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000014">
        <property type="entry name" value="Protein hob3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037429">
        <property type="entry name" value="Rvs161/Hob3_BAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="4">
        <location>
            <begin position="27"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="272" mass="31035" checksum="223DF5FB45925114" modified="2020-06-17" version="1">MSWSGFKKNVNRATTQVMMKTVVGLIKGAEIGHVEKTNDRDFETELRRYRVLETAANKLQSEAKGYLDSLRAMTASQMRIAETIDAFYGDAGARDGVSRSYKQAVQDLDAETIKALDGPYRTTVLEPISRFCAYFPDVNACITKREHKMLDYDALRAKVQKLVNKPDKDVTKLPRTEKETEMAKQAYEQLNTQLTEEIPQLIDMRVPYLDPSFEALVKIQLRFCAEAYSRMAQVQQYLDADTREQYAQGQLDARVEQVLQEIRELNIAGTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZU1</accession>
    <name>A0A6A6NZU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleolar protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_385947</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZU1"/>
    <dbReference type="OrthoDB" id="427002at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009383">
        <property type="term" value="F:rRNA (cytosine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1170:FF:000001">
        <property type="entry name" value="Ribosomal RNA methyltransferase Nop2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023273">
        <property type="entry name" value="RCMT_NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF30">
        <property type="entry name" value="28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02012">
        <property type="entry name" value="RCMTNOP2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="12">
        <location>
            <begin position="364"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="657"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="723"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="456"/>
            <end position="462"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="507"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00082314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="750" mass="81830" checksum="D93B1D442FE896D7" modified="2020-06-17" version="1">MTLNSSAAPATASLPAFSAERMSASVRASGTGFRARSSLTLSSGRWPARAAKAARRSKQGPPAPLDESLVTRKRKAAVAVPEPQLLADKKRRRADLKNDLEKPVKSVGKKEMVASEKGGKRQEAIPNGKASRKASKGRGTGNQKPAQEEEVESEDEDEALWEDESAEEGGLDDLSGGNIDLDELSEDDLDNSDTFPLDADNFLDEDDEEVVDSDAEDIRRGAHMWSEDEDEDDAEEKLTAANIEGLSRKLDTKLAQEAEDAQAELDDAAMQTNIVGDRPKVLEEEDQDEDQPSAHLAPDLQLLRTRITDTLRVLDDMASRGEPGRSRADYIAQLLKDISTYYGYSPHLAEKLFSLFPPREAFAFFEANETPRPVVLRTNTLRTHRRALAQTLINRGVSLEPVGKWSKVGLQVFESAVPLGATPEYLAGHYMLQAAASFLPVMALAPQEGERVLDMAAAPGGKTTHMAALMHNTGCIFANDANKERSTALVGNIHRLGARNTIVCSYDALKAFPKIIGGFDRVLLDAPCSGTGVIAKDPSVKTNKTELDFVRLPHMQKKLLLAAIDSVDHRSKTGGYVVYSTCSVAVEENEEVVRYALSRRPNVKLMDTGLPLGREGFVEFRGKKFGKEMKMARRFYPHVFNMDGFFVAKLKKVGPTPRGAVKATGKKEGAEDGQKVNGGGVGVDGEVDKTPVGEEEVEDDFGGWDEDEDRVYIERALKKAARKKGKDPKVVVGRGTQNGSVTGKVKAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZX1</accession>
    <name>A0A6A6NZX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_261080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZX1"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="24"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="23012" checksum="7D9AF001316D6A01" modified="2020-06-17" version="1" fragment="single">LLAESHGDSSSSWSPYIDLLPDRFDTLMYWTPAELDELQASGVKSKIGKLREDQRFMEEIVPVVRRWPEIFGFQGEDDKKVLEAAHRMGTLIMAYAFDVESEGKEVDKDGYMSEEEETEMEKAMVPLADMLNADGHRCNAHLFYTPTHLSMRTLCPVPSGSELLNDYGPLPRADLLRRYGYTSPTYAIHDVAELSHPAILRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P080</accession>
    <name>A0A6A6P080_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein SEC24</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein transport protein sec24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_385719</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P080"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01479">
        <property type="entry name" value="Sec24-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041742">
        <property type="entry name" value="Sec24-like_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="18">
        <location>
            <begin position="186"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="19">
        <location>
            <begin position="260"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="21">
        <location>
            <begin position="507"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="20">
        <location>
            <begin position="601"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="17">
        <location>
            <begin position="731"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2457400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="881" mass="96966" checksum="60D4591EC02DCA83" modified="2020-06-17" version="1">MEYDGAQAGHKKKRVYAPQAYEFGANVPQQPAGAPPMAGGDALASQFGQMNIQQPAAPQPPMASPGMPPGMMPPQPGPPQPGMAQPLPQPTVQLNQLYPSDVISQPFNVYELDMPPPQISLPPNTSVTPSPYANCPPKYMRSTLNAIPTTHSLLKKSRLPFALCIQPYAALHDAEDPVPVVPDQVISRCRRCRSYINSFATFLDHGHRWRCNMCNLTNDVPQAFDWDSATQTSVDRWQRPELNYSVVEFVAPQEYMVRPPQPLVYLFLFDVSYNAVVNGLLATSARCILESLDRIPNADRRTRLGFIAVDSSLHYFSIPRDGNELSDPSMLVVSDLDEPFLPTPEDLLVNLSESRANIENFLNKLQGMFQETQNGASAMGSALRAGHKLISPVGGKITVLSSTLPNIGHGKLEMREDKKILGTSKEGSLLQTGNSFYKSFAVECSKTQVSIDMFLFSSQYQDVASLSNLPRYTGGQTYFYPGWNAARSEDAIKFAREFSEYLSAEIGLEAVLRVRATTGLRMSTFYGNFFNRSSDLCAFPAFPRDQSYVVEVAIDETITKPFVCMQAAVLHTTCNGERRIRVLTLALPTTESLSGLYASADQCAIVEYFSHKAVERALSSGPEAARDALQSKLLEILTTYRKELAGGSMGGGGLQLPANLRALPVLFLGLIKNVGLRKSAQIPSDLRAAALCLLSTLPLPLMMQYIYPKMYSLHDMPDNAGMPDETTGETLLPPPVNLTSERIVPYGLYLIDDGQNQFLWVGRDAVPALVMDVFGLEDKTLLKQGKSSVPVLDNEFNERLRAVIEKSKDHRAKGCGSITVPSLYVIREDGEPSLKLWAQTLLVEDRADQGVSVQQWMGLLREKVSEPVAAVTPLILSTWPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0T7</accession>
    <name>A0A6A6P0T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_363780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0T7"/>
    <dbReference type="OrthoDB" id="5412996at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="17246" checksum="2E6F74D0D502BC7D" modified="2020-06-17" version="1">MHFEHLSAQHNDAVESEDDCRRNYVTRHLFRKLACEGRPEHHPEFETGPFKLFRDNLRPTNVLVTKSNAVTGVIDLEFTIAARKSWAFDDIFFNRLDEKYFGKAEKDWVTHWLPLLTEEQRQNMEPFVWRKMAERADRRLADLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2P0</accession>
    <name>A0A6A6P2P0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_22454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2P0"/>
    <dbReference type="OrthoDB" id="2142503at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025353101" description="Integral membrane protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16488" checksum="429CB1B906C986B7" modified="2020-06-17" version="1">MGRHNSSFLILLTLVALISTTFAFSATSFCKCTCFSNSTIIPLNGEQRQPSPGSDGGESSSGNDKGGSTCNDCNRQFCLDYNLPICKGAKEEDVFTTCFQRDSAKDQAVVLIFIVATAGLLIYAAVRPWVEQWIANARERQSYVPVSGQADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Z6</accession>
    <name>A0A6A6P2Z6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_284688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Z6"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF3">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="415" mass="44410" checksum="2D6AD75B0E584418" modified="2020-06-17" version="1">MAGPVRQPIDVAALERYVEANVPDVKVPIAVKQFGFGQSNPTYQLTDRAGAKFVMRKKPPGKLLSKTAHKVEREYRVIHALAGTDVPVPRAYCLCMDDAVVGSPFYIMEFLDGRIFEDMTMPGVSAADREEMYLMVSGGLAGPGPGGEETRFHDAARTLGKLHALDQAAVGLADYGKPAGFYARQLALFASLSRAQAAAVDVDTGRPVGPIPRQAEMLGFFAGEAAPPGPRDRAALVHGDFKIDNLVYHKTEPRIIGILDWEMSTIGHPLSDLCNLLAPWTVVSLALPTAAAARSPARPPLPRSANLAFHPATARAGVPPRPAMLRWYAAAAGWAPSPADLAWGAAFSLLRDCVIVQGIAARYAARQASSERAREYAAQLGPVAGICWRAVERAREEGRKGEGEGEGEGEGKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P317</accession>
    <name>A0A6A6P317_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P317"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="182" mass="19824" checksum="9277B1B4D6159BEB" modified="2020-06-17" version="1">MGTILTQTVARSLEVAMNPQEPSPPTSGPRIPKGPLKPPSKKQTNVFSYTEPAITPRDLLLQCSRKKDGTHPDAHAPALAPASRQYTCRLQQTRVSDISGNAPPLCSHQATRVQLRHPAVAVPRRKVRGAARRDAESEPERRRPGQRFSQCRDLKEAAEMLAPPSLQAASQPSSEAASRGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3H6</accession>
    <name>A0A6A6P3H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme/RWD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3H6"/>
    <dbReference type="OrthoDB" id="5596422at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23814">
        <property type="entry name" value="UEV_AKTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="11"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="313" mass="34503" checksum="9B1471F18B52EF7E" modified="2020-06-17" version="1">MHAHRAARIISQTTKLTRSSASLRSVLPNGVYVTIVQGNPTLWEGVLFVRKGPYAPAILRFQISFPPEFPSMPPLITFSSDIFHPLLTPLTTYTYTTGSSTSETVSASDEERLPPGGFSLRHGFPQWFGRARRSDQGSREASGSQASQQEPSDPDERALASPPLSTDGKAHSAQSKDPLSIRIVEVLRYIRSTFTNETVLDSIPLETAANPGAYHAWRTHRAHALQHSTSPNKGPSERSHGESPTVRARRPGEWNWEGVWEERVRKGIHASTSEAVLYGTFGGDDIIRFSDIDTATLDKIRTELVTQDITATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P408</accession>
    <name>A0A6A6P408_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_275130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P408"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="17201" checksum="7AF976C77D800132" modified="2020-06-17" version="1" fragment="single">GLSSPWHSVYGPIASLLDADETDRDKLTATWRDNKAGELNFVGIVAVIFSTIITGSLGWGRALEGPPATTALWYSALALALTALASAIQLTVTLNRLSGYPDALFRIRRLLSARGADVGTPLEERRGAAPSARQVYAWESAAIGLRAALLLYIVGMMVLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P452</accession>
    <name>A0A6A6P452_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_410621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P452"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016814">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01298">
        <property type="entry name" value="ATZ_TRZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000014">
        <property type="entry name" value="5-methylthioadenosine/S-adenosylhomocysteine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050287">
        <property type="entry name" value="MTA/SAH_deaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794:SF11">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794">
        <property type="entry name" value="AMINOHYDROLASE SSNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="55"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="467" mass="50037" checksum="DCF8EC98EAD255E8" modified="2020-06-17" version="1">MLYTKATVITMDASRRIIDNGAILVRGKNIADIGKTDVLVSKYPDEDRVDLQGRIIIPGLINIHMHTAQTLLRGTADDLELVSWLCERIWVLQGHFTPEDGYAAARLSIAEMLKSGTTCFLESMFADRYGFYGLCRAVADSGIRGCLAKIVMDTGSYAASSAWAMHPGLVEDATSLDKTLAEHSRWDAAAAGRIRVWFGARTPGGVSDALYRAMMAHSEKRRIPVTMHCAEVSADRDFFAGLGPDRGGPHTPTSYCDAVGLLGPRTVLVHMVHLDDEDVARVAASGTHVAHCPSSNAKLASGVARVPALLAAGVNVGLGTDGAPCNNTCDMLAEMRLAGVVHKAREADPTVVPAETVLEMATINGAKALGLDGDIGSLEVGKKADFAVIDTRKVELRPVFSPASVVVYAASGRDVEMVVVDGKVLVDGGELTTMDEQEVWEEAQWRGREVVERAGLSGEVTGRWPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P472</accession>
    <name>A0A6A6P472_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_385077</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P472"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051299">
        <property type="entry name" value="AB_hydrolase_lip/est"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005592">
        <property type="entry name" value="Mono/diacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640:SF1">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03893">
        <property type="entry name" value="Lipase3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025352763" evidence="3">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Mono-/di-acylglycerol lipase N-terminal" evidence="5">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="104"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="308" mass="33744" checksum="63E72B1D34A591E9" modified="2020-06-17" version="1">MVSLTFSFFVYALLYTSRVLAIPTLQVRDVSQDVLSKLELFEQYSAAGYCEDNNDSPDTQLSCEAGNCPQVESADTDTQTEFENSLITDVTGYVAVDHTNCLIVVAFRGSRSVRNFLADINFVQVPTDICATCTAHKGFWVSWLEARDGVLDAVEGAADENPSYKVVAVGHSLGGAIASFAAAQLRNDGYDTALYTYGSPRIGGSEIADFITNQPGGNYRVTHYNDPVPRLPPALVGYRHIGPEYYIKSKNGEEVTTNDVKVCRGSLNLGCNNGHVVVDVEAHLWYFNSISACSSDDLLEWKRDVQVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4N1</accession>
    <name>A0A6A6P4N1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAVE protein 1 C terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_284071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="342131at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="2">
        <location>
            <begin position="599"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1310"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1310"/>
            <end position="1320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1361" mass="152418" checksum="2D3D84740DFDCDD7" modified="2020-06-17" version="1">MRAILPGRPQAELQAVATGLWEGHQIIGYVSGNALVILDGANSILQTTYHEHDDDLATIALDEGTGKIATASASAVHIYQPYGKDEGDLKWSLQYSLALDNANDTITTLSWGSSEELLVGGSSLTLYSTRNDWEKIWSKPLANCAKYAQFSHDANLIATTGKYDRLVKIWRRLSAEAHFDYSYLSHPATITGMHWRRPFKGQSVENVLYTICCDNKVRIWVPGDTHGLLVLRLWGQIDLLESIQPRSVLNGNHPQTRYAFIIDSRDFTIATERAVEEAEQVDGDQHALQHLIEVAKRSPEACVVLDERGNMSAWGLENVGSKHRKATDIFNIAHGEGLRIHFAKEPSGLEKNVQFYNFCEPQLGGRFTLLSHHFDGRIEWFEGGLSQLFDPSPITRRLQRKTVWTGHSHPIRKVVRTASGRALVSRTGNSEGIVWAQKDTRNGTTLARHSTIKISEHIHRMWVLREGDYTVFLHHESISLWDTRGPKAVEAARLPYTVKGKALCLLHIPETKEHEGRVHLATISSEMKGVAWEVKLPEVGNDTGAGSAPSIHGFSTFDLGSGDDLAFVLPVDPAGTDTVHPGFLDTFARDVAISYTKSGVIKSWTARVDVAKRKLEWLLTSTVETSVENPFLVSGTSIRKAALVDAEKTSLTIWNTRSAQLEHEEKFDGQGEIGDLDWSSTPDNQSILAVGFPHKVVIYSQLRYDYLDAGPSWAHIKEIRTRDLTPHPIGDSVWLGGGHFAIGTGHQLFVLDNQIDVSDNLIPGLRVPKRQSTSLDIFTVVSRLNGPLPVYHPQLLIQCILSGKIALVHKVLINLYNKMKFFIDGDDLDSFLGLSADDFSSEQDIGVNTARKEMRSYYADFSEAEPDVVNTDVAHSLNGLLTRCQVPLLSSREQFNLADIIECVGVVEQHRRSLDDNGTRFLLFFREHLLRAAQPTRQLNISWREIIWAYHSTSQDVLVDLVSRHTHGRLLWEDAKESGMFMWLTDLTTLRTQFENIARNEYTKTEGKNPVDCSLYYLALKKKAVLVGLWRMATWNRERTQTHKLLQNNFNEPRWRTAALKNAYALLGKHRYEYAAAFFLLAGQLKDAVNVLATQVGDTQLAIAVARVYEGDEGPVLRSFIEDRIIPQAVRDSNRWMASWGFWMLNRKDKAVRALVSPLEQLVSPPQSPNLQSKLFLTDDAALIVLYKQLRDKSLQTLRGAIMVSPKLEWDFVLHTARLYQRMGCDLLALDLVRTWEFLASWQPRPSAHAPANGSPLSPRYPGATTADLRALNIDPRRLLRRRSSLVIADLPSPLQNVSMSQLSLRNGIEEEEAVSDGDSGDGGVRGTRPAPTANGTKEEKKKPTMISEPDPNSLLDSFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4W2</accession>
    <name>A0A6A6P4W2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4W2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="227" mass="25123" checksum="EFB51A31429FDE5C" modified="2020-06-17" version="1">MPKSQRIKKIAPLRIICGTLIRKFWVRPGLPSVFCRADKQQASVARRWTTSGTRKQLLRTRPGFKSATTLCGASYLRRRGVAGLSGPSTAPSSRTFSATRRNKNPGDFRFEAGFGLPGGTTAFEPSSDQPSDIDVGRRGRWAKCRRGAKRRWLNLFWWPGTSDKRYAAPPNSHLLLPSHFPPRATIPPASIPCSALFRSFKLTCALLPFAPVALSMRRAASPEQVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5R9</accession>
    <name>A0A6A6P5R9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_378526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5R9"/>
    <dbReference type="OrthoDB" id="4161595at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="650"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="769" mass="85214" checksum="4BE38642973B8D50" modified="2020-06-17" version="1">MPSFRSPAEISRRMAMEGLLNAPEPLPVTPTQVEAAEVLMTLHEEDKQSKPAEDHDQSSTVQNSPETEDDTLSAQHSEKSDKTDTTRKLPTAAHAGDKHARSPSGSPDAQPPEKRTKPSEANKSSKTAHAGDKHARSSPESLDYPDDNDVSDRAKLRRIFMRARQSVRPVRHTNEDSGHNQTMAAQPPPEEGSAGGDSDTHTVAATDFRTPERASEDAEVPRDFECVIGADIEEAGRCYSGQYDRKYARKCVSDFFGRNKLETRMIPKWRSACRMHYQRTAYKRGRWQQRRIDLIREQFQLNYECRPDLLYSVAPAKREQERLMRYLDRVQKRLPPQPFEKESAEDAHNFAKGKSQYMAPVWILAELADANQFGRHKTMADCLEIVDTLEKHLQAGHCREVPLIEFVPDWPLDYKEKFLIQAKHHKQEAELEEEAMSSNITPEPHNSSPGGQRFPGSAGSSSHTRARSTHMRAQSLDQMVTNTRRILGRSEEIPAIPLPPVGSTTGSQGSNDVSSARPTQSERTIAPMPSPLHANALGASRVLPPPTPTHPPGPAPAAHAQHPPPPQMQYPYGPLQSQATALPPHMRSQAFHGYPQAPHQNQVQTPHGYPMPAFGQYPGYPPMMHPWQHMAYYGGYPPYPGPGFPPGMYGPPAGQHHAGSPTYPGPPMSPPHPQAAPQQHMALPYPQTASQPQIAPPQLHPAPQQRTVPPQPQDTREAPFMGSNTSRIATLHPQQQQGNVAGENSVPPTPKALTGDDAVDENYVTPRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Y7</accession>
    <name>A0A6A6P5Y7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_299937</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Y7"/>
    <dbReference type="OrthoDB" id="434240at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015113">
        <property type="term" value="F:nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000382">
        <property type="entry name" value="Nitrate transporter CrnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="36"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="500" mass="53514" checksum="52E8A77A05614002" modified="2020-06-17" version="1">MGFSPTLLVQAPEVNPINKKARSIPALNPIDMYGRVFTFAWMGFLIAFWSWYAFPPLMTKTIKADLHLSQKEIANSNILALTATLLVRLVSGPLCDRFGPRLVFAGLLLTGAIPTALAGTVTNATGLIILRFFVGILGATFVPCQVWSTGFFDKNVVGTANALTGGFGNAGGGITYFAMPAIYDSLVGDRGLTPHVAWRVAFIVPFILITACALGMIFLCPDTPTGAWANRMQNLDRNIEEEHNHGGIVSNQGGHLDKVPAEDKKDASSDQEAGTVAVGEAVVIDQYHHESVQNPTVLEILKVMASPQSLVLAACYVNSFGGELAINSILGAYYNKNLELGQTQSGRWAAMFGLVNVLFRPLGGIVSDLLYKYTNGSLWAKKLWIHFVGVIAGCFCLAIGLKDPTELGMMIGLVLGLAVFMDAGNGANFSLVPHVHPYANGIVSGLVGASGNLGGVIFAVIFRFTGNYHQGIWIIGVFFIAINLAVSWIRPIPKGQIGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6J1</accession>
    <name>A0A6A6P6J1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_281933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6J1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="20282" checksum="5BE6C0F25FE61FFE" modified="2020-06-17" version="1" fragment="single">SQNQRQSVPTEAAVKSEIPPLLRVPPEIRREIYRYLLPSPPGRQFRIIPDRTTANSCGFKWARPNSSKREPREPCSLAILRTNHMIYYEALAMLYSENKFHFITVNYLPVLDFVRRLSPEARDLMRQVRLTLSAIPEQEIIQRRPSTHDTFCTVLYDYLTGLTNLHADPWTWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Z7</accession>
    <name>A0A6A6P6Z7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Letm1 RBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_272534</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Z7"/>
    <dbReference type="OrthoDB" id="73691at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Letm1 RBD" evidence="9">
        <location>
            <begin position="128"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="299" mass="33801" checksum="F031B8EAD7BCAC28" modified="2020-06-17" version="1" fragment="single">VNPPVSTLPARIDVPSRSEDQSFAHYLFQTGKIYARFYKDGVKAVWRNHKAAKALRKQNRQRAAPTLSSAAPHSSSSSSNNFACALPMPGWTRAEYQLLVRNAFDISRLPFFAVLFILVGEWLPLVVFAFSNAVPWPCRIPSQVDADLWRGEDRRADAAKKLLERAQRKATQGMPVVAVTPCRPPPSSPERLYVPRPMLLEVLLPHLDRRALLHMARALDLHAHFWDHIPEVVPLPWDVYLRYTIRQRVRYLAYDDAMIMRDAKGAGVAALSAEEVKKACAERGLDVRGKDEGTCRKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P798</accession>
    <name>A0A6A6P798_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_280902</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P798"/>
    <dbReference type="OrthoDB" id="762982at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="746"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="845"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="858"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="890" mass="97938" checksum="C6E087FEC595A82C" modified="2020-06-17" version="1">MTPTPPSTTSSSTGQSPDAQYRVVRKRNRVPLSCAPCRHRKLKCNRAHPCDNCTKRGDVASCTYATPSNRKRNQTSHGSSSSPDEMQSRIDRLEGLVLSLMTNGAQSAGPAAAASAVAGSVSGSSADAHLDIDDSQDMIKEDPEGEEEEDEVDHVAKSLGVMKVDNNRAVFASEAHWYAILGELSEVKTYFNEHKKQYDEQLKKYKAAYGDSEAPGTSFLFSSVQPADRETVLASFPSKPVADKLISRYFNHYDPSIHIVHGPTFQKEYDQHWLTPHETPIIWIGLCFSMMCIASQSYGRAGDEPFEYKGKSKEMAKTFRRLTTQCLYLADITQPIAYMLETLLLHIQAEYGRARDSEIGILVSVSIIVRLAMRMGYHRDPGPYASVAPFQGEMRRRVWSVVRQCDLLFSSQSGLPPMIRAKDTNTEFPRNIYDDELWDGIQSLPESRPLTEMTPVSYMNAKSQLVYLYGEVIEETQSVTCPSYESIMKLDQRLREAQAMLPPHFKMRPIEDSIRDSSSLIMQRFILNMLVLKSLCVLHRKYLSLARKNPRFAYSRRTCIDTCMEMLQHQVTLHTEAFPGGRLSNVSWFIASLTTHDFLLAAMMVCLDLYHTAEAECKGRTAMAATDVYGFNQERRESMLIAIERSVKIWGTLKDSSMEAFKAHATLTIMLEKLRNHEYLRRPQQMPRSGFGGAGMADMSGVESMNVAPEHSAAMTLGMLSSGGVTTPGGSTNMFDSVPGFTFTPDMASDISGSTSTSQASQQPPQQQAQTSGLTPNFSGDAVGGPINAPSPFSSLFGPNLGLQGVDIPGADMTWDAWDSYVQGNDQLGSYYNLDSIGVNSTGLDALGGGNQPAGHRSQGQAASQDGPTTQSGSGSVFMGVNTPDKGNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7N8</accession>
    <name>A0A6A6P7N8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cysteine synthase 2</fullName>
            <ecNumber evidence="4">2.5.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cysteine synthase-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">O-acetylserine (thiol)-lyase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">O-acetylserine sulfhydrylase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_384416</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7N8"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000049">
        <property type="entry name" value="Cysteine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000096">
        <property type="entry name" value="Related to cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="17">
        <location>
            <begin position="75"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00079149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2459985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="422" mass="45635" checksum="D1FAAB9E4A2A10C3" modified="2020-06-17" version="1">MDGKMRLCLVAAFATGVVVTLGLQSVTSSSTRRENLHRRNSRTTLRRLFQAIGEDLVLRDNTMDRSKTPAPEGIESCIGNTPLFRIKSLSDATGCEILAKAEFLNGAGNSPKDRVALNIIREAESQGLLTPYSGDMIYEGTVGSTGISLAAICRARGYLAHICMPDDQATEKSDLLLKLGAEVERVRPASIVDRNQFVNKARARALEHTQDPQRPGRGVFADQFENEANWKAHFGGTGPEIFRQTEGTLDAFVSGAGTGGTISGVALFLKPRLPNLKVILADPQGSGLFNKIKYGVMFDPKEREGTRRRHQVDTIVEGIGINRVTINLEAGRGLIDDAIRVTDREALAMARWLVEKDGIFAGSSSAVNCVAATRVAQKLGPGHRIVTVLCDSGTRHLSKFWAKAGSIGGNVDITLDNVLQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P871</accession>
    <name>A0A6A6P871_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SPT2 chromatin protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_361938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P871"/>
    <dbReference type="OrthoDB" id="5430658at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="42790" checksum="683FBF029B900100" modified="2020-06-17" version="1">MSFLNSVLSSIGTGRPPNVASPTTPGTVSKPTPSPTAPTAGASNNNVSKQTAPRPSAPVSSSDNRKDYAAATKQNSSASELKRKASTDASALRDDRPKIPRKDSQQQPPGARLPGAKPFVASQTAASRPAAAGAGAVKPTAAGAGPAASNKPPVASPTTASRPTAGGAGAAKPAAASAGPAVSNKPPPKKGSYKEILARAQAASQAATAVGTIKHKPIEKKPLTKKALKEQKLAAKHAVKPGTTAGASSGHSRNSSAEAAGKAGNEQQKERKKPRADLGYKGTMRQSAPAAPAYKGTMGVGSAKKPGQQQQNAKAGRKSSTTGGKEPQNDKYYGYFTDENEEDEDDYESESDMEAGMEDVWMEEELSTRLARKEDEEALQQEEEHRREKERRKRMLMQKSAEAAAKKKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8C7</accession>
    <name>A0A6A6P8C7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_184939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8C7"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="371" mass="42386" checksum="32C25AB512228355" modified="2020-06-17" version="1">MMQNNFTSSWAYSTAMCFSPERRLTSAFVHSLSDHETDDVINKITAHRDDIGRPGLLPSVLLAPRVHSANTKVRDCHSLIAHIEDHTGIFPNWHPNSDCCAKHRKDHKGQKRHFTIDFDQVTNDLTSVSHKLAYCEYVSEVHLPMFETILEIESRVDRFNMDAQPKDRTVEFFQPRETGEAASRLRIRNELLKGSLHDTTRRARYLSKRSQAQVQTIYSLVAQKDSLIAQKNNALSMRDSAAMKVISVITAAFLPATFTATLFSTTFFDFQPEKEGHIASAWLWLYFAVAIILTIIIFSWWYVSSRHVTKKIHKSLGRTEDGERTPLPNRWIGSLMADMYGVFTSPFRRKKAQGDAESSDSSGYDLDKHML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8C8</accession>
    <name>A0A6A6P8C8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_176536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8C8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="182" mass="21070" checksum="D9C2C7B17311B505" modified="2020-06-17" version="1">MLRCVFFLYCFLLVTFFSSRRVLVCAGAYLSSSYPLMPDCQYWVYFAFLRCFSFCTFLFCIFWGHKRHWLVLWHISALIFFFVLSLQARRWGLSGCFAAFLFCPIPLLALRVTKFKACCIVASLSDSMLILRSCQLLDTFPVLPSLPFTPRLCFFPSCLHVHIVEREQSTMMAMSSCEVGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8J5</accession>
    <name>A0A6A6P8J5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Golgi CORVET complex core vacuolar protein 8-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_281626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="2">
        <location>
            <begin position="689"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="3">
        <location>
            <begin position="1232"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1350"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1481"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1481"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1494"/>
            <end position="1513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1564" mass="171599" checksum="0264D54CCA28D862" modified="2020-06-17" version="1">MEEVVREERDRVGHQGDGEKEEEARTNGVGFHGYGDVEKVEDSETDTQSELPVRSAPQRAASPAESMSTPDDTPSIQGSALSSPGSSVPASQASLARPHHPHALKPFDRRFSSRLSSSPVQSPRTNSPAFLTPRSRQTSLSSVGFQGPEEADTPQAPWEVVRWTKLKKITAQVFSEAGKRNFGRPTCLTVAASIVLGTSKGLILVFDYHQTLKSIIGPGTPAIECGAVTALAISADHTTVAGGHMNGHIFTWELARPAKPFLHISPLERQTIDRRSVDGHVAGSAVVHVGFLGTRHTALVSADDGGMAFSHLATRGLGAVGRTVKTTRILGRYPLLANSNERPRKPSSVLAFSPLPLGNVEQPTDGLGLTALLTPYLLVIVSTTPVAQTQHKSSRPKELAPHSALSGCLAWFPAVKLKKPSAESKEAVSKTKLVYCWSNILTILDVDVEEAEDKDKPPVLQFRPRSRWRAEEAIVAVQWLSRSVLAVLTISQRLLILEDTSSLRMTDTFDLIHKHIFHQDLFFRQLQPVVEQLDEGDVSMHGVVADAFYMSFRAYKGRLFLLGFNDTAVGTLSNWADRLVALMEDGDFIGGITLATSYYNGDADKLTVGLPEDPDARHSLVQERLLEMISASLRYAFSGNENGHSNHPSEKLLADLATASFTACMSMQEVDFLFETVYERYEEASMEGVFFDALEPYILDEEITAIPPDVLKDLVTHYAAQGKASKLEEMICRLNTQTLDIDQTTTLCRQYKLYDALIYVWNQALDDYITPLIELLNIVKVLQHDGQNDNAVELEYLGSAQKIFPYLAFVLTGRIYPSDGPIPDEQARKAKSDLYGFLFSGKVVEWPPGSRNIFHASTTNSSEPAFPYLHLIIRFDTGSLMSVLNEAFEDSFLNGNPQSPSVNGAASRARPSSSQGLGLVPTRQYIVSILLDLVSSERFDPEDSIYVYMFVARNLPKFPQFIILPGSSLHRVLEGLCQYPSEEVADDCQLSVEYLLSVYHPPDTMALVDLFQKAKFFRVLKSVYRGARQYAKLLQAHFDDVENRADVFACIGDCLRPNRGLTKKQVAEVEAIIVSHASDLADIDTVRTAQTIKAYAPQLLKSVLEGIEDSSYAQYIFLQTLIEPQSKHQFTRVDETVGPQFVERYVQLMCKFDSSRVADFIGFLKSGDLRLDRVLPAMESSGVIDAAVVLMARDGLVREAMDRLLKHLGTLETALTGLINAAVESPDVANTEEAVDDLLDGVQKYSKVGIWLCQGQTRTMERPKTQQRKIAHDMNTDPEKGLAMDERLWLDLLDQVVSMTRAVGVAAAHLEAHQPASASSSIDTERITSALRTAVQQAFTALLAATSAPKAKPAAPSASPARPPTASAPTTTASNPSFLVILRAFLARAARSSPTLSDLRSVLTSIFAAYAHESTILSLAARFLDNDLFARVEEAYALRQRGWRPRGNACEGCGRRVWGPGAGGEIWEAWERRSRREERARRKRFAGAERDRMVGGGAGGAAGNGAEEGGQGGRAGRMALGPLLVFACRHLWHRTCLEQALFEKDKARGHAEGSPAGEPTCPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8K2</accession>
    <name>A0A6A6P8K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_178018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8K2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17787" checksum="746D8D34FC9573F6" modified="2020-06-17" version="1">MPGHGVLRWSSSAFPGSFDSRAIRHTYANHSNPTRRCGSFDVTDRAQNEILSRNDFPRLQSPPEVSQPIGFAFLHARCRHHTRRSPPPQMCLPMICRSGGMLLLFSNRTHLHVFLCLSLMIVARRLLTNMQGPDSSITSNSKLVSFPTQAYLSLVVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8P9</accession>
    <name>A0A6A6P8P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_160984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8P9"/>
    <dbReference type="OrthoDB" id="4500315at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000396">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="641"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="685"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="730"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="757"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="793"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="825"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="525"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="863" mass="94683" checksum="B5FDD52A243655D0" modified="2020-06-17" version="1">MVRWKKFSMSGRSGEKQASAAASTDDFHSYEKANRPERWTLGILNDKETDEVPGSILLLSAESKRNEPLGLRNTPARTSASSLPSPYPPSMLSRRSVQSVEKKRTPDGKIVLDPQPSSSPNDPLNWPAIRRDAALLSIGFYCMVGGGMTPILAAGFHDIAEAYDVSVSSVALTTGLYMMGLGVGAVVVSPTAILYGKRPVYLFTAIIFILTNVWCALSPSYVSLLLARIVQGIAMSPIECLPSASVAEIFFLHERAYRLGIYTLLLLGGKNLVPLVSAVIIQSLGWEWVFWIVAMIGGFGFALLFLFVPETFWDRTPRPRKHSHHTRKSIASHMSHMTRPASLFRRTSHMTTATRDHVGTDGAGPSTPGVGKDMPITIPETPGTLAQRRRSRHVGFQDSEKPEEELPEKPAEEVLETPVKTPADNRQTDGAGEDSQPRDFAQDGEVSAAEEKGGPSAENGDHGTQATPSSPASHKHSWKVEPKGGAPLTPELRNLNSPYYQKKAKEMDYFSIGNGIPSRDIEAGRASIQTPPGGDTPSLPATPAAVHRPSMRGPIPSGDSVGGDMAVSDRTTSMSPGPLERHVTYDPPSRASSHTRASDVPVNEYTAYYHSAPPKTFLQTLKPWNPRLHKDKWWKVALRPFVLFGYPAVLWSTLVYSLSVGWLIVLSESVSEIYRNQETYNFTALQTGLVYLSPFIGGVLGTAVAGKVSDVIVRYMSRRNGGIYEPEFRLVMAIPVAVCTTIGLMGFGWSAEERQKWIVPTIFFGIISFGCSLGSTTSITFCVDSYRQYAGEALVTLNFSKNIFHGLVFSLFFNHWLESDGPKDTFVALGGIQMACLLFTIPMYIFGKRARMWTVRKNLMEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Q5</accession>
    <name>A0A6A6P8Q5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_298113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Q5"/>
    <dbReference type="OrthoDB" id="5570009at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="219"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="476"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="661"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="743"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="817" mass="89108" checksum="9A359DB9D2D465E5" modified="2020-06-17" version="1">MIDHVLGRPSVKFRKIQVFAVVSFWSFYLYKGDRHGPPLLRRVSSLLTPRLTAWQTLVITILWLYIARNFGKLVGLECPEPLANLYSRSYFRATWITTALDAGFWSAMSIRRRWARELASVVFSLYYLVCAEQADDKVRKVRGCLTVDHLRVSWNKGTSPIISSFAALLRPRFMRYSPRAIRIPRPRASAYKEPVHAWLYFDGPVSALKSMDKVVLDIPGGGFVAMTPRNHDDKLLAWAGRTGLPVLSLDYRKAPEYPYPYALNECYDVYHTIVATRGRCIGFSGATVPRIVVSGDSAGGNLAVGMTLMVLESGSTDTRRWHGEKPLPPPEGLVLIYPALDMNIGSWMTDEQMALIRDRRDRKVNEGVLRRKSDDYRKLTPSTPHHSDDEDEDEDKVEGLSGKLSKVDGSAIASSPTAIHISAAHTIDSSATTAAVSAEGGASKSQTIPSPTAAVAQQTSQTTKPQQLRTRLAMSSMISYFNDRILTPEMMRAMIILYVGPHHRPDFSTDYLLSPLLAPEGLLARFPKLHLLTGERDPLVDDTVIFAGRVRQAKRAAWQERRDLGLPPGGADKGKSWFDERDHVEVVLVPGISHGFLQFVSVFPEGWKYIFRCARWLRELFDGVDDPGEPLLQTPAAGTASAAASAAQTPWAEAVGGATATTAATPDGGAGTQDAEEAGGLARPHTPAQRQRHHRRIPTESSIDEDKPLEMTVLRGSRDKARRRGSGSGSGRGNAGSGGGADGAVAVNGVPVARGKRVRRGAAAGSGVGKGASKGERRNRRKSLVSLASEEDLLGRRMRGLTGGLMGGGTGDGMKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P953</accession>
    <name>A0A6A6P953_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dynamitin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_407940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P953"/>
    <dbReference type="OrthoDB" id="4977at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="450" mass="50444" checksum="05546147E2DA6B59" modified="2020-06-17" version="1">MTQSRKYANLPDLDSAPDIYETPELTDDASTLRLTSFNCQTSTAARSPSPESSDAGNNPAIIRNRLEPDQARTHFLPSRVDARDVDFSDRISRNRQSYRTASRKRRGSRYSDAELGDFSDEEDETAERKLARLRREVEELKLDFESRQQEDQSDSNVKETGLEPDDADPAETIKKISDTLDAIYLQRQGGVKGAEAQLERTLKKFSTTQISGSDAPRPQPPDSEDNVKTKAELLAMRQQQGVTLMKVSDFDARLSKLETTLGLNGVNMPDVADNPPEPILHTLENLGRQLSMVSGTSSIDEGSRRVRQLIQESERLQEVRRAGLAREQTRSAENGSEESQLDSDDSESMSKIMALYGTLPTIDALSPTLPMILERLRTLRLIHTTAGAASSSLDEIEKRQDEQADEIRRWRESLDKVESNMKDGESVLTENVKVVQEWVQNLESRVAKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9F6</accession>
    <name>A0A6A6P9F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_164396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9F6"/>
    <dbReference type="OrthoDB" id="1862401at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="470" mass="52221" checksum="B2551B56DA6C3636" modified="2020-06-17" version="1">MFLSRIFSRLGQSIVGLRVPETSEEFSEETSEEFSEELKLSLFDQTMLRTYIRTIACFPFPDASRASEANEAIKAGLQATISQYPFLAGKICLGPSGKDDGKLSLSYPRKAQGVSEAGIFTLKDFADPSKPESVIHVQANYIDGGLLLSVYLHHSVGDGVSIGTLIRCLAENVRLRGEFKSKAAAADPSLSRRELDQRAFPPGTPHLPTPEFRIVDIRESSIVPSNLPHAQVQVSGRLFVLTAAMRAELKAKVMDHIKNSDDYRPGWWVSTMDCVAALIWILVTRARAPHLDHTVETKIGMTMDVRKKLNLPSDYFGNAVLFTFTSLPVKHLVDEARPFYALVAGAASKIRLAYLHFTETAILHRLTMMAGLKDVRNISCAIDFNHGHDVFWNSWGDFGCDAEFNIPGAASDTPQWIRKPWSRQDGGNMLMPKKPGKDVDWEVLVQLEMPDMERLCSPGGLAEWAARIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9N4</accession>
    <name>A0A6A6P9N4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_186544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9N4"/>
    <dbReference type="OrthoDB" id="2142759at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="156"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="25467" checksum="D37702427EAF90C0" modified="2020-06-17" version="1">MSTRTAYEDPSHLDGAHDLPANVNDVTVTIRHPGYDDNCNILMLLPGLDDVDGAIDYDTALAACGIAADNNWEGFFTLDQAGRHRVVRPADGLLREKDCYFHVPGIYPIVPSFRDWQFPRSLPSPWKECTVSPAPAHRIPREVTLTEAVLARDISCRLTNHIEGTENAHLIPRTEKKWFDRNAMARFAQISCAGVDAINVPRNAIALRSDIHTLFDNKRFVIAPKQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9V9</accession>
    <name>A0A6A6P9V9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBF/Mak21 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_333244</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9V9"/>
    <dbReference type="OrthoDB" id="28947at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040155">
        <property type="entry name" value="CEBPZ/Mak21-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048">
        <property type="entry name" value="CCAAT-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048:SF0">
        <property type="entry name" value="CCAAT_ENHANCER-BINDING PROTEIN ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="508"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="836"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="668"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="836"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="875"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="934"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="953"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="979"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1017"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1057" mass="116939" checksum="7CA2873458A7D9D9" modified="2020-06-17" version="1">MGKNNLPPHSRAQNGGKNEFAAAKASRNNRAPRDFKQAAGKKDRAPKMVLEKLTFQPRPDWHAADLPSLPAAVSTTLEDLPPSTYRVLDASAAELRHYAAELLEAENASFASNQSANSQARFMSTIMSSGTLEDKVSALTLAVQESPLHATRALEQLAGLARKKNRDQALLALAALKDLLAHGALLPKERKLRYFAKQPGLVAALAKGLVGQGNEEEDGQQEHEHQHKKKGKKDKKDKRHGGKSEVRQQPALRQWHSGDPLPGGVTEAHLVTWDYEDWLKHAYFSILQILEAWCNDEIEYARGRALTFVYELLKEKPEQEENLLRLLVNKLGDTSKKIASRASYLLLQLQVAHPVMKGVVIAAMEQDLLFRPGQSAHAKYYAVITLNQTILSMREEDVANKLLDIYFTLFLTLLKRKDLRAYESRKDLVRQQSKTQGGGGQAGKKASAKARQREEVNKAEDELNEKIIAQVLTGVNRAFPFAKTDDAAFESQLDTIFRVTHSSNFNTAIQALMLIQQISTAKHYAADRFYRTLYESLLDPRLRTSSKQVLYLNLLYRSLKIDPTKHRVLAFVKRLCQLVPHHDPSFACGILYLVSQLEKEVPAIRAMVTSPEVGEDEEEERFVDMPEEVDGEVNGETSKMNKQVGGVAAHGSKPDSVTKPPQWPNDVDPGDTTEEDPSVQELIPSPPVAHSRRTYDGRKRDPEHSHAERSCLWELLPSTLHFHPSVALFASRLLSGGETPPQPDPASHSLMHFLDRFAYRGQRLRTGAGGKETRGVSIMQPLSGGSAADVLVMPGGRGAVKGERPVNEVFGEDEGGYKDAREDEVFFQKYFRQKNMGRKKGKEKRKRRGKPGEEGSSADEDEIWEALVKSRPELEGDEEGDEDESDLDGLAEELDDEPGGGDSEVEGLEEFMRDNEGEQNEVLGGGLQAHDVDDGGASEGDGDEGFDFAALESGDDEGFVGSDEDLPSDVGVALGWDADAGEEEDGEGEDVEDEVGKKKRKKSDGKAKGKEKKGKAKAGDAEEGSRRTKKRKLKHLPTFASVEEYAKLLGEDEDEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAL4</accession>
    <name>A0A6A6PAL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HAD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAL4"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.750">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF9">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="39813" checksum="2929B22525E9B8DF" modified="2020-06-17" version="1">MASDLDLTSFRLLSFDIFGTLIDWETGIVEALDALTEADADAEAEAATAGDDDDDDDDSVPTAPIPRTHPLMALSKAAKLALYERHERRVQADAPQTLYRDVLKEVLVRMLRDAWGAARAAGAGTAGTADDDNGDGDDDDDAPREGPSTSDEAAGAPRQDAAGATARATGLSPRAVARAAARFAASVGAWPAFADTPPALLRLRRRYPALVALSNVDDASLRRALAGPLRLPSSSTPPPRAASAATTTTPTIGADPAAPAADADPRASSSPFAAVYTAERIGTYKPSAAAFAHLAARARADFGAGRGALLHVAQSLYHDHAPAARAGLRSVWVDRRGVMGGGDGGAGAGAGVEGARWDLRVGSLAEFADLVDAAFEARGGRETGEGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAM9</accession>
    <name>A0A6A6PAM9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_166102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAM9"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="146"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="437" mass="50303" checksum="A8BA333888724B6C" modified="2020-06-17" version="1">MITAMAQSTLSKFVWWVFDRSLNQNLEQYLEDYISTDRGLEDDDARDIAVVLQQRSRGIIEYMVSRDSPRTLVILKMIGMPDLSDKFLNAGVTDMWYPFDDYLLRQIISDKETRRLFLEKQNLVLSRHMSPDPDRHQHLLHGDDHFEEKKILGSGGFGLVSDCHDILNNRQVARKLIPRGRTISRRQAAISADAFANELAILRRVSARNLPHLVTVVGSYTDPTYFGILSTPVADMDLGKYLEVRLFNNSHKKWYGCLASALCFLHGMKIRHKDIKPRNILIYKDDVLLADFGISYDWTDRSGPTTSGRPVARDPRYCAPEVDGWESRNESADVWSLGCVYLEMWSAFSGFEIESIRQHFRENGSRSDIYCKNREALLSWMAEVRGRHHMQGLSQWISQMLKEHSNERISAAGLRDRIRLQAPYYVGLMGCRCGDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAR9</accession>
    <name>A0A6A6PAR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_361015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAR9"/>
    <dbReference type="OrthoDB" id="2157103at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="18142" checksum="DE4564D32E9F585D" modified="2020-06-17" version="1">MVNGSELWVPGTRPYHSLDFCLNCSPFENTPRHAGLLPINIMISNRLPRSYFKVESFTPKFPSRPLPQCVHNASPKHRLLSTSTSRAKDKAENEGEKSQQDASSSPEKPGRNKTKTMAEMDEEVRMKMEGRAGDGGEAGRELEGGKAVSMKRGVRDNMFRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAZ5</accession>
    <name>A0A6A6PAZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS19m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_334339</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAZ5"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="10782" checksum="6B32B3F67D76EF9E" modified="2020-06-17" version="1">MQPTRILFHRSVWKGPHIVPLHIARPKPGERATPVKTQQRSATILPSFVGLRFQVHNGIVYHDITITEEMVGHKLGEFAPTRKRFKYTQTKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM2</accession>
    <name>A0A6A6PBM2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Casein kinase II beta 2 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_419020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM2"/>
    <dbReference type="OrthoDB" id="5415241at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038816">
        <property type="entry name" value="Stationary_phase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42342">
        <property type="entry name" value="STATIONARY PHASE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42342:SF1">
        <property type="entry name" value="STATIONARY PHASE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="53599" checksum="CB4126354C2259B3" modified="2020-06-17" version="1">MAASAGHLHKLLAKNVKLLKYTFKSAQHLVQANLPASLRPYYAEIQPILVRNAGARQPVHPTAALRQAKGRWYTTRSAANAFVRRFTTSRAYSSFANGVGGGLRFDKSALPQSRTRAFITASSGRAPFASTLRPNLTGGTLGRTAGGYAMPGSGRVSGARFFSHGPAAPAQVVNNVSQAVRAFALGGQKARFDGVDARGRTRWRAVSALQDEVGRKVQGALPRSSPGSYVDFAVNPTITAITPLTAAVPGFGQAAASASVVQGNSLAQDGLLGALSADFARALKDLSATLADLQRLADLGDLPITYEVPGKKGKSAPEDMFNSSAHILRVHFPGCDADTVERLCAELGVSRGLVHQDPDFDAFAGVEMALLFPLAPSAEPSECDYIIQQQKPQPEQIRWQHMMTPSAESVSLREHDVLSTRSIRSGSGSESGSGELVPIEDMLSAAGQENPWASVTPKSPSGYDSLHTSSASDAHSPLEYRGFEGICRFIEQCDAATSRAPQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBS7</accession>
    <name>A0A6A6PBS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBS7"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="62"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="330" mass="36356" checksum="DB3F88EAFF803E6A" modified="2020-06-17" version="1">MDKVTTEEGTHKLDDGFEVYTKKWKPSEAPVARLVFIHGFSDHCNAQSQSQDSHSVHHYIGNNYRDLFPTLASRGIEVWSFDQRGWGRSVHNRSQRGLTGDTTQVLADLTSFIRAAVPSPPSIPLFLMGHSMGGAEILTWLARAPGPLRSRVRGVLAESPLVGLHPSTRPSGLLVAAGRLAGRVLPRWQMVRRLDPRLVSRDEQVGRDYVADPLCHDTGTLEGLAGMLDRGLEMQAGEVVVPAEAGEGGRARLWVSHGTGDGVCDFEASRKWLEEQPVEDKSFKAYEGWYHVLHAEPGNDKVMFANDVADWVLARTPPLDEGGKPVKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBY0</accession>
    <name>A0A6A6PBY0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylulose kinase</fullName>
            <ecNumber evidence="7">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_368637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="7"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBY0"/>
    <dbReference type="OrthoDB" id="1728974at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:D-xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07776">
        <property type="entry name" value="ASKHA_NBD_FGGY_SpXK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000118">
        <property type="entry name" value="Xylulose kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042024">
        <property type="entry name" value="D-XK_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF57">
        <property type="entry name" value="XYLULOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="9">
        <location>
            <begin position="310"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="627" mass="67726" checksum="C73E94E28586805B" modified="2020-06-17" version="1">MALYLGFDLSTQQLKGIAVDSSLKLQHEAKVDFDADLSKYGIQKGVLANPAAGEIFAPVAMWLEAVDLVLSRLRDAGLDFSRVRGVSGAGMQHGTVFWSAAGERMLERLRPDSPLVDQLDDAAFTSRFSPNWQDASTQAQCDAFDEHLGSSTKLAEATGSKAHHWLTPLVACPQRFSGPQIMRFREKQPDAYAKTARISLVSSFLASIFLGRIAPIDIGDVCGMNLWDVRSGKWDERLLTLAAGEPEGVAALREKLGHVPEDGGGAFGPVSSYMAGRWGFPSDGRCQVIPFTGDNPSTILALPLRASDAIVSLGTSTTFLMSTPEWKPDPAYHFMNHPTTAGLYMFMLCYKNGGLAREHIRDAINEAGTDRSSRSSSSSSSNSSSSGANGANGAKSASEKWAAFNETAVETAPLQPTADGRMRLGLFFPRPEIVPNVRQGTWRALYEAGDGTLTPAKPGTGDWPLPHTDARAILESQFLSLRLRSQRLVHPPGGAQRRLPAQPRRIYLVGGGSANPAIARLCGDVLGGAEGIFRLDIGGNACALGAAYKAVWGVERDAAGRETFEDLIEKRWFEEGFVRRVADGYKEGVWESYGEALRGFDMLEKQAIAEAGNEKALKKVVKPQYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCQ9</accession>
    <name>A0A6A6PCQ9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_368883</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCQ9"/>
    <dbReference type="OrthoDB" id="5297881at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="634"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="704"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="771"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="634"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="722"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="780"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="834" mass="90477" checksum="FD82C4029A5000D4" modified="2020-06-17" version="1">MSNRPQVGIDRLPARRASNEPREAMNCKSCRKRKIKCNRMRPTCEACQVFACPCIYDAVPKKRGPKTDVLEALLKRVDGLEKRLHDEKKADGAETDPPTKDFNEPPGKDQAQPDRPTIEIPQKSSVSNSVLSPVEAGQPAQHLPSGLLDIYFARIHGKPHHILDEPTTRSRFQSGQLPNHLMFAVCAVASRYSPEFGGYNAAVRAGQDFARRSRMDLDVEEPTIENLQTLLLLAQAGYQAGKGKKAYMHLSSAISMALALDLHRELPAGLKVPPAEREARRRLFWACYLMDRFAACGSKRPSLVADESIMLRFPSWHVHPGSMVIEGDYFPNGSNVQYMAGPGKQSQGSTGMLIGICRILGITNRYLAAGGVKGDSHFPWHSLSNLSKIRQDLDIWASETHDTFISVDALFAQPDSAILALSKLVYHLIHCLIYRPFLPVDLTELSGTAQHQSWQIEATNLCFLHANAIAELVEIGRASSMVDWPEFVGYCICTAGTIHVHGAHYHGREGDVFAASADFLSREMNQLSELRFAWAGVEHQRETLQAVYGCHSELVKSLASNPMRFSPVFQLEDFFDRYPGRYFDGAHLTFADVVVDAVHESVTPYGVGQRNNLYIQPNVHMQGFYPVQQQLQPQFQAGASQQSAPPKKKRRPTNPSPTSNPAGMKPGLSQAQNGEPPPDPGSAVDLAPTISPFTPTFHFHAMAADLPPASNGQPPTGSMHDQSQSQNQPQQQQAGPSGAPNGGPAGGGPAAAAAAAAAAANGYDPMFSLPAAGPPYEAQTTPGATSATGSTHSHPSGSGGEDKDPFLSLLEQLAENEHSRGGPSELDFFLGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCT3</accession>
    <name>A0A6A6PCT3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_388768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCT3"/>
    <dbReference type="OrthoDB" id="412005at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029731">
        <property type="entry name" value="OSGIN1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15192:SF8">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15192">
        <property type="entry name" value="PROTEIN CBG05349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="58594" checksum="F631DD3B14BC6B50" modified="2020-06-17" version="1" fragment="single">GNGPAALILSYILHGHIPFYDARTPHPDPLVHARLSARPNLLDLARTAAELDAHIASSLRYFSAQALPVNALFDSLLRPNADTAAHGDWDGADEGRDSADGANAAPRSCIEWRYDPHMKVQHIVLGSAPRAGGQWAERDPHALTTTMPLTKDGEDVTADDIGADAIGTLSYADMLSLPGYTFAQHHRRTHGGASPPPFLRPPRAAVADYYAAYPAAAGIADAERVGQTAAGVRRLPASGRPGFYVASHRIVAGSLVLASGTFSRAIPPPAMLAPLLQQPQPRAPAPGALHDRDPEEALLVIGSGFSAADAILAARPPTRRIVHVFRWDRTGERPSPLKGCHSQAYPEYAGIYRLMKAAAAQQQQQQQQQARPQQPPLSSSPFLTRRDWVATYTGLPNAAVESVIWDEDDARAQRDDDGNDNGDAHCCRRPRHRRHRAAAGPATVTLCLENGARAAFRVGALAHAVGRRGSLSYLAPELRREDDGLISGRALRARVVAASAAAGGRPDLEVAPGVFAIGSLLGDSLVRHAFGGCAVVAGRVLERERGEGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDC5</accession>
    <name>A0A6A6PDC5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_4611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDC5"/>
    <dbReference type="OrthoDB" id="5313079at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="7">
        <location>
            <begin position="20"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="460"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="465"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="619" mass="70223" checksum="899CA1F1F650DD11" modified="2020-06-17" version="1">MARVARALEGLDWRDNSNLDPLGIFYIVVAILHSLAVITGLVLLYKNRDTPAVRIRNFNIVAPAIVCLHIYSTLVLLVYPQNGFFKCGTEFWVMSVFLPVGYGLFQASNARLLSYSAAQQHFSQVYSVKAMSGLSRVRNSRFFLADLLRKTYVGVLLGLIVQMLSTIVLFFGSFRFHRSYGFFGDHVNAAECRRGPEWIPSVLWQAFWTWGFGPYLMYKIRHLRDTRYWAWQTRLAIIAGLPATPLWLAFLYGNSGAVGRLNLWFPPPAWFLPSVLTIEAISIIFPLLDNHRSRQFERKLRKLSEDTESISGRSSTSSRERYSMSALESQVASRIEPLLDFAASREFTAENILFLREVRDYRRRWDTPLHRACALTPRESMERYQDAAVVFFTLVNPITALFNINIKASTLTAMAAMFKDLRYDEQEFGALTPGGAPAPASPGVVSTAAPERRDVACPWEDDRPQQQQQQQQQPVQLSRQPSSATMQPQAQAQAQAAGSADELTLLDRTRTTSMSDARAGRRRFLHTRDGRPMAVPDAFSPRVFDAAYDEIKVLVFTNTWGRYVRRSYLSHAGRRVFFCLPSLGEIATFVLTRWGWFAGSSTASTPKVWLARTTDTRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDF4</accession>
    <name>A0A6A6PDF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_277585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDF4"/>
    <dbReference type="OrthoDB" id="2110361at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="676"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="750"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="755"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="816" mass="90274" checksum="E5C6F53ADA2535C7" modified="2020-06-17" version="1">MPGHHPYGAAQSPGSLGGHAFSHSYGTSSNSPGGPGGGFQEPIGADSAISNAGISPTHISAASLSAQKRAYRQRRKDPSCDACRERKVKCDATETSSCSECSSRSVKCQFTKDTNRRMSSIKQLQDLQTQLADARNQITMLRNKLEQNGIMDVDPTSDDVPFLNLADATQGERRRRPPAINSLEHVRKNMRIYGRGLFKAPPLFRQPLQQPAHTEPAPVLPPWATTDRLLTQFHEVFQLHAPLLHWPTFLNEVREVYRKGSFQSCPQVWVALFHIVLACGTLQTLDYSSGAETPKPDNEGIRFLNITSRTLNTFADDLTVDHIRVSMLLCVFIMEMNSRSAAWVWLGGAVRIAQDLGLHFEAGSSPTVEAEMRRRIWWTVYTYDRLLSLELGKPMLIDEDDCNVDYPSPVHERQAFHLGSQQLLDYSHQRTVQQAMMGVLRSISQLKRALKSPVVSAATLRHYGIFFYEIQSKLPEPCDPTTEGHPDPLLLYTFITLQLTRFYLYRHNLSTACQPCERTESLDRCLGVAQETVHYVSRSIGMSPTSLGAGQYSTTSGDDLWKRRIAKATTNILCTHMWRCALVLLIRCDFSAAITCVRIMAAVGNARKINTACGRYLAFFVDRLTEQIRSGTTRSQLGQDEEMVAYVSADMQGDPESSWVWHGGEAGAKLNATMRPTVEGPSREHTESAPIPAAPAAMPPTPSPGPGETYPAPPPANPFVILTEQESAEWGGWDRLERLIFQVMEEQQHMSGNLQQAQQPAPPHQYHQPLHNPGKRVQLGPATGDSAAPPASQAGGVNLGGSARIRISNILMDESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDZ1</accession>
    <name>A0A6A6PDZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDZ1"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43054">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43054:SF1">
        <property type="entry name" value="SCYLLO-INOSITOL 2-DEHYDROGENASE (NADP(+)) IOLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="332" mass="36182" checksum="2DB6154EB6580738" modified="2020-06-17" version="1">MINFSVIGTGWISDSFVQAAHKTKAWKLTAVYSRTGENAENFAEKYNVTNTYTELDSLGLDPEVQAVYIASPNSLHYSQAKLMLVAGKNVILEKPATSTVAEFEELFALAKQHRVFLLEANRHIHEVNFKVLQRNLSALGPIFGATLNYASYSSRFNNVLAGETPNVFSLKYSGGALVDLGVYPIAAAVALFGAPKGQIYRPVKLPNGADGGGVTLLDYGNFSVSITASKVFTSTGPSEVYGQNGTLIMNGVTDIDRVSFLNAKTKETVDWAQPKAPLNLLEEATEFARIIKGKDWDAATKLEQISRTTLAITTDLRRQNGIVFDCEKNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEI0</accession>
    <name>A0A6A6PEI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_313069</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEI0"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000014">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="206"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="647" mass="70591" checksum="876D95CC26ED3432" modified="2020-06-17" version="1">MAPKDMKQSPLERRKGESALSDFADYVQKQQRLRRPGAAGQSDAGDSGYGTATRSGLGGAGSGSRASAASHEEHDELRVLDELGLADESTAIRLRHLLLDVRGDADESVALLTGHLNGRLEEGRGETLFDIGLEDNGDSMGFEKEDWGFALGRLRQVAEVLQADVRVLMTRNVNEGEEEVGPMGPKDEACSGKVIVRKKPQEVDDVIEMRIAVVGNVDAGKSTMLGVLVKGGLDDGRGKARVNLFRHKHEIESGRTSSVSMEIMGFDSRGEVVGSNVPGRKLTWEEIGRRSAKVISFTDLAGHERYLRTTVFGMLSSEPNYCLLMVAANNGLIGMSKEHLGIALALNVPVMVVITKIDICPPNILEQTITQLTKILKSPGARKIPIFVKNRADCINTATQFVSQRICPIFQVSNVTGESLDLVRTFLNVLPYNGNYNDETPFEFHVNDTFSVPFVGTVIAGVVKSGVLHAGDPVLLGPDSLGQFTTTKVRSIERKRIPATVCSAGQSASLALRNVRRKDVRKGMVVLKPGDNAAAGAPPPKVHREFVAEVLILSHATTIKKKYQAMLHVGPVSQTCAIIDIDRSYIRTGDRALVAFRFVQRPEFLTIGDRILFREGRTKGLGIIKQLGYDEKHPLNPEGQKDEEERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKW5</accession>
    <name>A0A6A6NKW5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL2m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_359315</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKW5"/>
    <dbReference type="OrthoDB" id="268576at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000128">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="10">
        <location>
            <begin position="106"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="9">
        <location>
            <begin position="209"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="313"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="375" mass="41527" checksum="ACD5CF6E8A424309" modified="2020-06-17" version="1">MLQSRVPLYRASSSCRCIVASLRSYSTAGTAVHPQSDNPVQPAVSNNNATHAPHSSSRVDHSFRIRTYKPQTPGLRHLKRPVNDHLWKGGPFRPLTFPKTGHGKGGRNASGRITVRHRGGGHRRRIRTVDFFRMAPGKHIVDRIEYDPNRSAHIALVTREATQRKSYIIAAEGMRAGDVVQSYLSGIPDDLLKSMGGVMDPGMLAAKTAIRGNCLPLHMVPVGTQVFNIGSRRLGPAVFCRSAGTFATVVSQDEGRKQEETIVRLQSGEVRRVSKHACATIGVASNPHWHFRQLGKAGRHRWLNVRPTVRGVAMNSVDHPHGGGRGKSKGNRIPTSPWGRTPAKSGFKTRRKRNVNKWVVHERERNQGKRRTGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL95</accession>
    <name>A0A6A6NL95_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_359389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL95"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="62" mass="7693" checksum="C812515E929E888B" modified="2020-06-17" version="1">MLKGQRHRRIQSCMFRSSMWPPHAHHCRRSDRPLTGFYQKYYRHQGYVRWGLFQETLDHCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLJ0</accession>
    <name>A0A6A6NLJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_425117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLJ0"/>
    <dbReference type="OrthoDB" id="3262926at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="163" mass="18013" checksum="43FE400276EC609D" modified="2020-06-17" version="1">MKFSLQFWFILIAEDPQSRTCIGLAFVATMSPEGAIAAPAKKDLSPTSFAPVLGPDTGLPTFRDGQPHEAIEPAQNQYPVHYFVLDRPLWNQEIEREGIESSPPRGGLFLTAKAVGCRVKRNRQTGRYVLADAAAAGEQKDRVLPIRNPEEELLFAALHDQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLK2</accession>
    <name>A0A6A6NLK2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_405189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLK2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="520" mass="56198" checksum="AA6304D1548E324C" modified="2020-06-17" version="1">MSDVRVPWKACLKGSQTLAMRFQSLVKQSIWRCSECHKTNQYVKYALRVYGPTKCQHCDHAPCKHCEFDEKVLELVLQNTLYTRKDQRGCIIIRTCCACGQVQLPRVVETAEACADPAFEAHYVVCGECAVAACSHRSCGNCLTARLKNSDVENEQRWRASLRDSVSPDSSEWEDSPDHPAEGHDDSSLYGLDIGGKSADGLATEVPAASASNLARAGQGQTGTDEEDEEEQEDAEAMTMGRNSREFKEYVREFDKTDAVSTCSKPHPTSKQIPPPQRSSMKPMTNTSAGSGSSGLPPARPVPSQTPPPPEQTTSPTSTPPGHVSKKPKLTHAPAREPERPPPRTTTTTSRERGRGHGQLPLRPRPAAFAPHPRGEGDGATRAAAEPARVRRRRPDEAWEPREPAPSAWAALAGTGPRSPGAAQDEREEDPSRPAKAHCSGPDMSDGEAEDGLGVESYGTETLRQPADYPKLGDMGSVPMLYGSAPGSQASSWRDEPEGTPMGGCDDFGRGDGDDDEDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLP3</accession>
    <name>A0A6A6NLP3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_258696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001724">
        <property type="protein sequence ID" value="KAF2452244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLP3"/>
    <dbReference type="OrthoDB" id="3261222at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18021" checksum="740B82473E92815E" modified="2020-06-17" version="1" fragment="single">KGARIHGVQWHVVKVDRVNKNTICDETRIRIHGDACERLSAENGVTIRKMHFLGQQSPDKLYCSIAVYLASREEAEGLLHRKFIEIEGELAYTKPYVRMATPQRCYNCQTFDNHKAHRCPAPEPTCGVCARTGHTNRECTAGEPKCVNCEGPHRASDRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLY6</accession>
    <name>A0A6A6NLY6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_358375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLY6"/>
    <dbReference type="OrthoDB" id="2537432at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF3">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="125" mass="13256" checksum="5D595A42E435383A" modified="2020-06-17" version="1">MSDHVVSTGRGGQGNIGHDPHTYVDAGIVREGTPVGEHSAGRGGAGNIGTSPRQGPVAKEHDVVPEMSMRPEQENYHTGRGGGGNVHKEKYGGHTHGPEHENLIDKAKHLIGLDKKKEGETEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM29</accession>
    <name>A0A6A6NM29_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_375262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM29"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF10">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025717052" description="Glucanase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="379" mass="40528" checksum="CAA7E62D68230E9D" modified="2020-06-17" version="1">MRAATLLAAAAALSSSSSFVAAKWLNDTGNPFEGRKLFANPAWATKLEETYEAFEAAGDETNAAKVRTIQDIGTFVWVSDIAGLDNIDEAVSAARAAKAETGDDLIVGLVLYNLPDRDCSAGESAGELSSAEDGMERYKAEFVDVYADKLAAADDLTFAVVLEPDSLGNVVTNQNIEFCAQATPVYEEGIAYAISALQFEHVNLYIDAAHGGWLGWDDNLAPTAEEFAKVVGMSGNSTKIRGFSTNVSNYNPFNANPRENFTEFSNSWDESHYISSLAPHLEENGLPSNFVVDQGRVAEPGARAEWGDWCNVAPAGFGMPPGTPTNNTHLDSVVWIKPGGESDGECGMDGAPPAGAWFEDYVEMLVEYAHPAIEPASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM44</accession>
    <name>A0A6A6NM44_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_358177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM44"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="66" mass="6982" checksum="1A058E3997A9D277" modified="2020-06-17" version="1">MNAAGDYSAAYCILHTDSEFTGHGMSHLHHALLSSIPKFSTPRSQLPHPKTPHRPSPSAAATTSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM88</accession>
    <name>A0A6A6NM88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">USP8 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_152195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM88"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16042" checksum="93BF8748514181B6" modified="2020-06-17" version="1">MSAASSFQPRPSTLPSFGSTRDMNAYNGGRDGGSDGGGGGSGCQPRPYKHISDLVAAAEKRIEKDRPITYLVQLADTASKQAQSLLDFRRPDLAYVEFVTAYEIVANTLPQHKDWPQLQGDRGSAHRTKLEVLKVYISSIVINFAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW2</accession>
    <name>A0A6A6NMW2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW2"/>
    <dbReference type="OrthoDB" id="4177236at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="164"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="384" mass="43770" checksum="CA329110E95210A1" modified="2020-06-17" version="1">MLQFIPAGVALAETPAMRYNRQIMDKLQKALAAHPEVDLASIVPKDYSNRLLKRKITKPNSRLAEELHGKSRKLNSKLSLSSAKVLKVEDLRDATVDILFPLSEPVRQIFQDNNDADPTTAENIDKVLGESAILFRHPVGGTVVLDCKPGIVVKVTPNSKDLTEYTTLQYLETVHPYIPAPRPSGAAKVGRYCLFFMSRIDGSTLEEVWPKLNHALKCSVQDHLNSALLKMRPLRRSEDQQLGGVAGERCKDLRRHVRVSDHPILTAKEFEDFQFSNPHYGSDEYIRFLRSLSPPLADSCVFTHGDLRPENIMVNITEESCILTGIIDWEFSGFYPDYQEAIKVTNSLAPNERSDWFDYLPDCISPRHHSRRWLLDRLWWKHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP03</accession>
    <name>A0A6A6NP03_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_145487</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP03"/>
    <dbReference type="OrthoDB" id="5584477at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="4">
        <location>
            <begin position="283"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="728" mass="83193" checksum="7A49AC53B19F9B6F" modified="2020-06-17" version="1">MAEMPTSEIIERYPIIDGLQSIDDLFRSFFMHTTITSYTAALRSMDNLDYYYLANELLQKLQTLSAASELRSLRVRGPLSADLSKLADEVKSGDFNEKRIDAILKAIFKQKSDHVIWHRVYDAVAEMTPPPYVLSQLFADEGPWMQGRSQFASTNQYRERVGWRLTQEVEAFQVGVPRLYETFFGCVSGLEVEAAHVFAKCQEGDYPLYSNEGGWRGWPQDAEPFEVSAWLSKFVEQLRTFARPGFIPDVRRFLQLPRLYRETPRPTHTLGIGFVRPGLDGVMTHWDQLLIPGGLRSDPRTMPAARMDLARYARLAFAVQETRRFVLGLALCGSVMNLLEFDRLGGMAGSEFDINQDGLRFVSVVLACLRMNDQQVGKDPTILRSNGRRYVEVERDGRTERIFFQELLSRSSNVAGRETVCWTGYLEGSEAVSFVIKDSWQNPGRAEGVLLREAAQKDVEHIVRYYHHCTVMVDGQIDDVRSNIRRGLGSTEAGGEQQLNRIHHRLVVQGLGKPIHMARSRIAFLAALIDCIEGCESLHKKAGILHRDISANNLLMYKDGSGDYRGFLIDLDIAIKVHEEAWGVGTRPFMAIGGLMNQPHTFMHDIESFFWVLVWISVCYDGQQKGARRAEVEKWDDYSVDLLAEIKYELISNRSRFLSWAFDNVAPYYRPLLPWIERLRAMIFPDGLLSRNRDLSMYADIVEVLRDAMNHSDMRVYDWVDNSNMQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPV7</accession>
    <name>A0A6A6NPV7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rap1-interacting factor 1 N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_374609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPV7"/>
    <dbReference type="OrthoDB" id="5399929at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022031">
        <property type="entry name" value="Rif1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12231">
        <property type="entry name" value="Rif1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomere-associated protein Rif1 N-terminal" evidence="2">
        <location>
            <begin position="265"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="961"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1195" mass="130297" checksum="8D6767632BD8CF09" modified="2020-06-17" version="1">MPALRKGSRTRSATAAKSGAMSPSVAASPLRDVDANAHSAVIDPATGIDHDTVETIDGAIHFLSGAFESTHLDLPSLSARACTGTPPRCRQRPMPKYLKLNPASKRPCPLDEAVELSSSSPIRRASPPGPTAAALDEAIDIPSSSDAPSAGDEAVGADPVDPPSSPPVVRPDTPPPAPSPAKRRRVDFNPSDDFISPPTSPFLARKPDRKPLPSAHTLKSILKRPCPLPESPSDPMSASLTQAPEAGDFVAFPDTLEWAVQQLSTGDRLACRDAYTTLIKTVKAYGNTPEIAPMKVKMALFMVFFRRDLVLPTSGEHSVNKFLVVNAIRLLDLCMDWPILAEAVDDGDFCTFVLDQAIAFLSNAIGAHVKHEVGIYLHILSHINFKICSLPQIRISRLFDCLDKVKSHVQFAAILEWRLLVYGHMLSQLRQLMINWMPRWLPTVFDAMFHDHPQVRETAIEIGVTAGATVGDSSLACRKLMNFLTTKEAKEHVKDWTQQDKKQKENKEEYDRPYIDRLLARLRNMFESNGGVDSEYVPQIGGVIILFLQTQRARLESWPYLRPWLSVTVQHAMNFGRLQTKLRAYKAWQQLIYVVRPDLTTSEPIRRMLGQPFAVLGAKDEKKGLSRPAKVGLWDAFCALLYCSMLPGAPPALLDVSWEAYGGPILPLIADDSQQGVLRTCRILTAQLGGRKNTTWDLRRVLSDNEPVRPEELARLNPQWVRSRIDKLLPLVSVCLDRAPWNTNGTAQLATPEPVWCNLMHSVALAGAQEVLVSSEFTTAITHIMNYLHDVGCRHATSLNTDSLPMWIQRFKLLCSTVVEHLGPSGHMNNELLIMLQNGAFEPVSSHRAAANGDRVTPMAVLDRWIHPIAGGAPKSGKAVSLPEKTGLADPAAPLLGLAGTAAAAEHDTSEIETQTALHEEVDTHIPDQEDDAPDVEPHAALEDDPEAQVPELEDEAPAIEPQATSHDENDVNEHMSDHEDDTHNCACCRYDPNDEEIFVPPSERTAAAATPAPAPARVAFERRAVAIDEEVHLQLQSEMAAASGRLPLATRVEDDGDVEDAAADDEPPTTDEDVEMQDAADESLGVTDDSEAAAIEEGAVARTGPAEPAEPVLPPPHRKRPQPMAATPRPHSSSAVPPADGARTAGIVARLQAMRAELAGLRGLTRDEVAGVNEALFELTGELYVARRAPEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQM6</accession>
    <name>A0A6A6NQM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_355191</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the synembryn family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQM6"/>
    <dbReference type="OrthoDB" id="5585685at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001965">
        <property type="term" value="F:G-protein alpha-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019318">
        <property type="entry name" value="Gua_nucleotide_exch_fac_Ric8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12425">
        <property type="entry name" value="SYNEMBRYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12425:SF5">
        <property type="entry name" value="SYNEMBRYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10165">
        <property type="entry name" value="Ric8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="394"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="499" mass="55637" checksum="6FB794FD4DE9F64D" modified="2020-06-17" version="1">MASATGAAAVGKRKLDEVADLLGKLRVDWNEKILLPQQRLAALETLKVHGRSPENADAIFTKEGIETLSKYGLDQVSWATSREALRVLANAFLLRPPTRQMFVDMGYGPKAAERLKNDSRDDEFLCSRILLLMTYDTDLDFNKLVRENQLADSMNQNILRHSKRFSKNSHKKGPQSTPQEEMAMSETLKLLFNMTHFYPELVPEFSKSIPNILKMLVRIKRRSPPLQPPVNWLVNALVNLELADEKSGTFSCGPMFPKFDQKCNVDYLINLLDKAIVAYKDADLEEKVAPPLTLLRRVFEIAPDGVRKWMQWLLLPTDDERSRPLGQSDTLSARLLRLSTSATDPDLRSNVSAFFFELSGKDATRFVRNVGYGFAAGFLLSQNIAIPENASEAWSTSGKMSSDDDGGSGGGDGAGGAGERSSKESVPVNPVTGQRLDAEEPDRGPPMTKEEKEREAEKLFVLFERLKATGVVDVENPVRTAMQEGRIQELPDSDDEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR10</accession>
    <name>A0A6A6NR10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-dependent deacetylase sirtuin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_292321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR10"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036054">
        <property type="term" value="F:protein-malonyllysine demalonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036055">
        <property type="term" value="F:protein-succinyllysine desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01412">
        <property type="entry name" value="SIRT5_Af1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="34254" checksum="7E95A92CFEC6D4EA" modified="2020-06-17" version="1">MASKAATSSSIPTADLESFSSHLQSSRRILALLGAGLSASSGLPTFRGAGGLWRTHDAVSLATPEAFQADPGLVWQFYNYRRHMALRAQPNNAHYALAQLARKTRDFETLSQNVDGLSQRAGHPGDKLHLLHGSLFDIKCGEFFCDYVQKDNFTNPVVPALAIPTGEIDPTSNAARGARELDISDEKVELPEVAIRDLPHCPKCKTGILRPGVVWFGEALPRDTIRYIDDWIHATNKIDLILVIGTSAKVYPAAGYVDTARARGARVAVVNTERTDAPGSGLTKKDWFFQGDAAEVVPQILKPIIGELETRAQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRP2</accession>
    <name>A0A6A6NRP2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 alkane hydroxylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_103515</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRP2"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF19">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025526107" evidence="8">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="490" mass="56317" checksum="3D4069407D9A3BD8" modified="2020-06-17" version="1">MGLAFALPLAALLAFLCKVLYSSLSNRNGMRKNGCSAPPKLPQKDPVLGLDEFVKWARAMGDGSIIRMFRQRHEKLGKTFQGVMLGTNQIYTMDSKNIQTVLALDFDSYGLEPLRGGVGEYLVGKGIQTSDGPFHKYSRSLVRPTFARNNFANFASLQRHVDEFMGHIPRDSSTFDIQPLLQRLFLDEGTEFLFGESAKSLSPESPQEMNEFLNAHEYAMRGLSIRLQLGKTLQVLHQDKKWFECCRVIHRFLDRHVYRALELQEMRDKSVLLHEMARVTRDPLDLRNQIFHIFFDVKKNISTIVSNVFFNLSRHPKAWQKLRAEVLEIGDDELTVDVLKSKIYLRWVVNETFRIMPLAWATARLSLRDTLLPHGGGPKGTEPIFVPKGTRILVNWAALHMDRDYWGDDVEEWRPERWQDKKPTWEFLPFSGGPRICVAQQLALSQAYYVIVRLMREFKNIESRDSRPFDTTTRLGVSNKNGVKIVLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRT2</accession>
    <name>A0A6A6NRT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amine oxidase</fullName>
            <ecNumber evidence="6">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_416754</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2</text>
            <dbReference type="Rhea" id="RHEA:26414"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:58855"/>
            <dbReference type="ChEBI" id="CHEBI:65296"/>
            <dbReference type="EC" id="1.4.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="6"/>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRT2"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097621">
        <property type="term" value="F:monoamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050703">
        <property type="entry name" value="Flavin_MAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43563">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43563:SF14">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="7">
        <location>
            <begin position="161"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="597" mass="65135" checksum="99B21E91F973AAC7" modified="2020-06-17" version="1">MSPERGISNFDPSELFSSPLHAHVAQIPGDACSIHIAGQIAVDKEGRTPSTYPEQIQLALSNLDACLRKAGSTRKDIVKLTYYIVNYDPKDRPDADLLAKSLDGHRPATTLVPVPCLVWPKILFQIEAIVAVRDPQLPSPFPSFGGAAQRTIQAIVIGAGLSGLQAAHDLQKAGVSCLVLEARDRVGGKTWSMPCANGRAVVDLGAAWINDVNQPRALALARKLGLEMVEQNIKGDCMMEGVGPFAYGGIPKLSENEQEDFVKVRDNMEKLCHTIDVQRPWKSQPKFANMSVHDLVVSQGAGPSVRKAASEVSALYFLLYCKAGGGFLQMRSDGKGGGQHLRFRKGTQSLSHGLVNALSPLTVRLSQAVLKIEQAATGDRCVVTTQRGDKFPCMKVIISVPTPLYNEIEFSPPLSTDKRELTSNTSLGCYGKYILVYSQPWWREQGFCGLAHSLEDGPVTLTRDTSSDIDDVYSLTCFIVGPSGRRLWQSPAVERHTRVLRHIDAIFDQKCPEPLEIFESNWEKEKYSLGAPCPVVPSKCLSILDRDRWGPEGNIHFIGTETSPVWKGYMEGALTSGARGADEVTTALLASNINAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRZ1</accession>
    <name>A0A6A6NRZ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRZ1"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="37397" checksum="28F4FE1DE13A7D11" modified="2020-06-17" version="1">MTDPLVLPDFDNLPPVNGMPLGCAWGLFDKDGKKDIYGTLNLLTPSVVRAAAGEVQEGVSVSLDWPLGAIKRPGFGRTPFSHKITSFEEGPAKCYGFDDAVEFDTQVSSQWDSLCHFNHQPTGLAYNGIKPTKAELVQSFGNEDKEGRMPTLNHWLKRGGVVGRGVLLDYKAYADAKGIVFDPFDNHRITVRDLEDVAAFQGTELKLGDILLFRTGFTEHLEAMSGEEQAAALDNWRACGIDGSEEMARWLWNKHFSAVTGDAYSLEQIPPIIDGEEKTVAHLVLHPYLLSLFGMPIGELWDLKALSEQCAKSKRWSFMLTSAPLNIAGGVGSPPNALAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS28</accession>
    <name>A0A6A6NS28_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_353768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS28"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF190">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE MIK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="37"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="YEATS" evidence="8">
        <location>
            <begin position="366"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="503" mass="56682" checksum="FDA7CEB62A17AC56" modified="2020-06-17" version="1">MTSTNSSFEPTSGISSWDWANRGTSHVTFSKHERVPLVEGRNLGHGVNGPVYETQVKGVRLAWKRKFCRRKIGGDELKEIEIIKKLSHIHAIRLAGSYTHGPYLGLLLYPVAQCDLATFLEDVDFLSRLSKGLIEKPSSDDIAEHSFRCCQISNTDPALTHLNLVVDCAKSRLWRILGCTASAVDYLHQNRIRHKDLKPLNILLSQDDGLWVTDFGHSVDVSNFSDSATSGGELGTLKYCAPEVAAYERSGRSADMFSLGCIFFEITALSCLDLRAQRGLRSRKDGSFHNNLDAIFEVFETFGSSPLDHLPMALARMMLSKNPESRPSSSEVCQIIHFLSSFFVFEPDVFQGFGCVHGLHRPTPNEKKSTVQEITIFIGNTSHEDHREFVVRYGEKRYKQPSVFFVEISSPDLIESVIFFQHSSSDEGVIVFPKPPFARRAKLWGTYTEAVVLVLKQGFWWDSQQASWIPGQDGGFRSILPLTWELQLHSPMESEMRQERICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS45</accession>
    <name>A0A6A6NS45_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_374170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS45"/>
    <dbReference type="OrthoDB" id="4359109at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="39"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="218" mass="24566" checksum="43F362A7A49B942C" modified="2020-06-17" version="1">MNHSNSENEYTVGPARCILAGVYAGPGHFRMSNGQNSDICYRDFELGELVIVLQCEHYYCADCTQQWMETSWPYACPYYKAKMPGDGECEWDPDIPYLAEKPNSVRLLVPQRGAADLEVKDALGAWFRPYGGGPMANLPDEPGPDNAPPQQMGLLQNLLQFLELDLGGDEESSDEEDGDAPEESDDAPDEEHWDSRDEEYFSDEFFIPLSEQDDDYDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSB4</accession>
    <name>A0A6A6NSB4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_290846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSB4"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000526">
        <property type="entry name" value="D-mandelate dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF281">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="68"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="123"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="345" mass="38303" checksum="20F269E5AEE1AC76" modified="2020-06-17" version="1">MAKPVVLHLGDDIKWNHELYKQLQDKFTIERSYSMDRETFKNALKTKQFGDFAAMYRPFWNTGGEMGNWDDELISLLPPSCKIYASAGAGFDWVDTKRLAQSGIIYCNAAAACTESVADAAIWLILSTFRNFSWSSTAARSLDPAQFSNANRNIAAVTHNPGDHSLGIIGLGRIGYRIAQKARCCFGMRILYNDIRRMSSDVEGTIEATYFERLDDMLSEADCVLVATPFAGDKLLDTAHFDMMKRGARLVNIARGKLVDEPALVRALEEGQLVAAGLDVHYDEPNVNPTLAKMSNVELLSHTAGASVESHIGFERLGMENIMSFFETGKALTAVNLQWIEQPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSS3</accession>
    <name>A0A6A6NSS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_351750</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSS3"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000025">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="530" mass="57185" checksum="14A200E561DE1034" modified="2020-06-17" version="1">MSYQNPTQIFAEDVTEEKGENARLSAFVGAIAVGDLVKSTLGPKGMDKILQSASTGEIMVTNDGATILKSIALDNAAAKVLVNISKVQDDEVGDGTTSVAVLAAELLREAERLVDQKLHPQTIIEGYRIAAQASLQALEKTAIDNSTDKAAFRRDLVAIARTTLSSKVLSQDRDHFANLAVDAVLRMKGSTDLSHIQVIKKAGGKLKDSYLDEGFILDKKFGVNQPKRVEKAKILVANTAMDTDKIKIFGARVKVDSTGKLAELEKAEREKMRQKVERIKAHGINCFVNRQLIYNWPEQLFADAGICSIEHADFDGVERLSLVTGADIASTFDHPEKVKLGTCDLIEEIIIGEDALIRFSGVAAGRACTVVLRGATEQLLDEAERSLHDALAVLSQTVLEPRTTLGGGCAEMVMAKAVDQAAQNVAGKRAIAVDSFAKALRQLPTILADNAGFDSSDLVTRLRKAVYSGMTSSGLDLLTPGGGIADMRELGIIESYKLKKAVVSSATEAAELLLRVDNIIRSAPRRRERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NST5</accession>
    <name>A0A6A6NST5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Histone-lysine N-methyltransferase, H3 lysine-4 specific</fullName>
            <ecNumber evidence="3 14">2.1.1.354</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_351654</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the COMPASS (Set1C) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the Set1C/COMPASS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="3 14"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NST5"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024657">
        <property type="entry name" value="COMPASS_Set1_N-SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017111">
        <property type="entry name" value="Set1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024636">
        <property type="entry name" value="SET_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11764">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11767">
        <property type="entry name" value="SET_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037104">
        <property type="entry name" value="Histone_H3-K4_mtfrase_Set1_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01291">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51572">
        <property type="entry name" value="SAM_MT43_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 14" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 14" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="17">
        <location>
            <begin position="205"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="18">
        <location>
            <begin position="1159"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="271"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="469"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="555"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="818"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="289"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="668"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="818"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="861"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR037104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2454811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1276" mass="141251" checksum="A5A5E226F06A7CD6" modified="2020-06-17" version="1">MGTFSYAGPGAPNSHTLTPLTNTDSSPPPPGSKQRGSGSPPPLQGGLVGSRTVGTQAGASLAASGRGGGASPYGASMLAGTRQDSGAATSAHNGGSATITPAHTPPQSNRQARPGPGEIKGYKTYFDPELITDPKRAKEKKMLKAKSRPFGQETDPSPPPDPRLAIAGYSTGTFNGVKAKLRPSPILLRPYPFDPKISCGGGPATQVVVTGFDPVTPESKLRTLFASYGEIAEINNKTDPNTGSFLGICLVRYKDPIPGRKNGIPAAQAARRAEKEGSSERINMNKIRVQRDRSGHRCKRFVEEAVKRNTAQRDKLAREERSLKPPPTPMSAIPSANIKNLGPPPDAPKGPSGKGIRPPEALRAPLLRPSSAAASLVEREPIINGIKRKPYIFIAKYYVPVLGATIPHLKKRLKLYAWREVRCDETGYYIIFEDSRRGEEEAVRCFHDCHMTALFTYVMNMECQQYGDPNYERSPSPERVAEEKRKQAERERLAREEEEDEEFEKQERARNLDPIKAAIEIFAAELKEKVLSDVKSKIAARALYDYLDPDRHAAKRRKLGISDPGEKESKPPTLMLMRGDDTPSVSGTPDSRNHGFSGSTGRHPLSAYDVNSIRPRGKRLQRGPVNAFADDRRKRMPQHSNQSRKPPVRHLHQQLRGYFDQEDDSDDEQRTPLTRDTDEQESRPLSRMSRSSTAFEVEDDLDGPPIRKRRKVEAEQRKHALVGASATARATAAAAAAAAESEDEAQDDLDDMSARLLRLMDDKEPEDMTLEELDQVIGTLPHYSKIRRRAETERAIRFRNKEDDELFGITESVDRHVDEDAVGDKARQKKDGREGAAAPEVTVDEAINEDMQPVEEIGKGVKTKKVPTSAARKKKEKEPKPKRKTKKQLLEEEKARIAAEVVTDVSAALPVPPQIEDIATPETPTVIVEEEDKKAAAKLLGEPLEEEEEEERAEVEWGVSTDHPRRTVEDDLSITLDIHGWQHLVKDDEDLRFLRKVLKDVPAASLGDTGLWAWKQKEIKLLNNNNRAVGVTTSAPHIDGYYMSNMTGAARTEGVKKILESEKSKYLPHRIRVQKAREEREARAKNNPQAATEAAKLAAAAKTASTANSRMNRANNRRLVNEMNTQKATMLSLGVGGTGVDGEAGVLAMRFNQLKKRKKLVKFDRSAIHNWGLYAQENIAVNDMIIEYVGEKVRQRVADLRELRYLKQGIGSSYLFRIDEDTVVDATKKGGIARFINHSCTPNCTAKIIKVDGTKRIVIYALRDIAKSEFAPSLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTH6</accession>
    <name>A0A6A6NTH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Survival protein sure-like phosphatase/nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_387336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTH6"/>
    <dbReference type="OrthoDB" id="4018688at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="5'-NUCLEOTIDASE SURE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457:SF0">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025529536" evidence="4">
        <location>
            <begin position="22"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="365" mass="39035" checksum="9BB5FDC741C68DDF" modified="2020-06-17" version="1">MRSSIAAAGLAALTVVPSVQATKVLLNNDDGWWEANLRETYRLLSAEDGFDVLLVAPVTGQSGTGGSAEYSEDPYLSYPGQYDSVPAGSPAVGHEPDNDRIWYYNGTPAACDFVAFDYVIPQIWGNGTLPDLVVTGPNTGHNLGPFVFTLSGTVGAAYAAVSRNVPAIAVSAGDVAGGHRPYTEVNETTPAGLKDPATIHAELTVKFVKELVQSTRSGNRFLPLAYGLSVNIPDITSMEDDSCIDPPFVQTRLTGSAITDIAAQEDESSSEPPVFHYESIYSDAVNECINGDCDLPGETAVVEDSCTSSVSVFTIDYDAPDTHVTKGVWNKLKPLVKGDEGSGHHWRRRGANAKYLGQRNYRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTS3</accession>
    <name>A0A6A6NTS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_399053</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTS3"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="307" mass="34962" checksum="1E8C4738BE3FAD3D" modified="2020-06-17" version="1">MYECDMCSATFWTKYDREDHLNDWDHWIECETCDRAFSTQRACNQHMNATDHWAPRYECETCPAEFRTQGAANQHMNARGHWAPSWPCETCSKMFHSEAAASKEEVDKHMTRAGHFKTYCPSCDKHFMNENNLRMHLNSKAHRGSGVLCPFCKTAYTTASGLLHHLERGSCARAPSLNRETILRLVRARDADGIITTKRIGWRDGDEDGGQARLRATPAAFNGAAWECYLCHRQFRAVEALDAHVNSPVHMQAVYRCPNVAGRCGREFTTLAGLFAHLESESCGFMRFERVQRSVGTVLQGRKMIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTV8</accession>
    <name>A0A6A6NTV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Non-repetitive/WGA-negative nucleoporin C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_81334</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051292">
        <property type="term" value="P:nuclear pore complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.440:FF:000001">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.450:FF:000002">
        <property type="entry name" value="Putative non-repetitive nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.440">
        <property type="entry name" value="Nucleoporin, helical domain, central subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042537">
        <property type="entry name" value="Nucleoporin_Nup155_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="14">
        <location>
            <begin position="124"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="13">
        <location>
            <begin position="695"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1354"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1363"/>
            <end position="1374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2455205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1504" mass="164756" checksum="966AD4AF9F8C4F15" modified="2020-06-17" version="1">MAAPGTPQRPMPGLYMNTPAPNRHDRGFGGNADQPFRPPVYRAPSGAAGGAAAAGVQNAQQAGQQNSRPSSAGRQTAQSITPVERAARAVNENLTRESRFPELDNYVTQGISSEYDLTTASQAWAPFERVRRFPIPDRIFEQYNRAQVNTMMGLLAEIHHAWISIDNSLYMWDYTNPNPELIGFEEQAYNVTAVRMIKPKKGVFTNRITHLLAIGTTQEITLLGMECKKGPGGVYGVELFQTRMSVPTRGIDVSVIEDGRDGRIFFAGRNSNDVYEMTYQQEERWFQNRCSKICHTSTRLQSVMPSIPFSVRPPHEHVVQMVADDTRSLLYVLSSESTIRVFHMRSEISFDCCITMTFMAIRTSIQHMVARTDLIDPTTDIASIAAISATESSRLNLMIITSTGCRIFMSATSGYYATDATSPPTSMAVHHVKFPPATAANGQPQQRTIQQQPGGPYAANQPIIDTNSRALIVTRRAARFPPGYFFCFVAAHAAAPSDELFLSAPDSGRMARPAEPQQMSRYFETGLWCDLGSRAEDVGVVSEGSGGAEKMPLGFGNEMAIQFDKPIAEIAILTNTGVHTFRRRRLVDVFAAVARRGAGLEGTQDAADTVRFIRRYGRTETTATALAVACGQAVSGGGASTAAGADGRVSGVNDPDVLDFARRVFIEQGGKPTLNENAIMAFGGHANPVENVRPSPRHDGIALYVARLVRRVWKEKVMEEKVIPGGGLEVKSTVLVDKLRSIQRDLAALQEFLSRNKAYIDGLAGPGETALARAATKQEEVALQGEHRALDALVKLIVSVIEGLSFVLVLFEGEGAVAARAAADILLSLPDTQRQRARELTYEQLFTSTPGRDLARELVKAIVNRSIARGANVDSVAEALRRRCGSFCSADDVVVFKAQELLTKAAEAGAATEGGRSLLNESLLLFQQVASALTGEQLKTAVAQYVEMEFFAGAVRLVLRCASMVDRAGQAAAWVRAGMPQADDRQKQFEKRTECYNLIHDIINAVDASVARTRPEHLADPHHPVARRKAEAYEEIHNSTDELFQTNLFDWYVAQGWEERLLDIRSPAVVAYLQSKADERLDHADLLWRYFARYNCFFDAAVVQLKLAKSDAFEIPLSKRIEYLGWAKTNASTGFGISANMGALRSPDSSMLSTLTGPRGASPAGSFAATDSRLSRQELLAEASDLLDMAAVQAELLERVPHHPRLTAENRERAIQMLNGPIRTVESLYHDFADEAGYYDICLVLYKISQYRNQAHIRSTWQCLLEKVVAEREVLGAAERRALERQVQRQRRGGAADAATRINLALWRNRPAPWAALSEQVRALGSRLGMDDAVFPVDMLVPMLERWSVTATTDPTSMLPRGGAAGNNNGGGGALAQLDPNEYPPPPPPPPHWVPTVMFDLGVPPDALYAVYEVLAFADMEPFTSRAGRRLVAANLVYVVCNWVERSEASGEWVCGGPEGQERVAEALREIVGQGWLAGRDGAVGEVRADVLEELVRKVELGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU55</accession>
    <name>A0A6A6NU55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_373379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU55"/>
    <dbReference type="OrthoDB" id="5423884at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="272" mass="29274" checksum="A5FB46045BA26EDF" modified="2020-06-17" version="1">MPAVPRAADAPGAEARSSRLLSSPVADVVPRAINNDAHDALAALRPRAESSKAPAAAPAADERVLLKRIPDGLPGPDPPFLVAARQQADNVIIPTTYDGLDAGPPAGTVVGIILGSVAGTLLILWLLSSLMAASEPADEEIVVRRHSHSRSPPRSRRSRRSGRTEMREFSRSPHRVVVEERRSGGVAAGPPPPGPPPVIVEERRERRVSGDDVVEVIEEHSDLTRSTSPPRRKHSRRSSGGYRSVDPNRYAGGDYPQHEVYGHGRRGSKRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUN4</accession>
    <name>A0A6A6NUN4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_72818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUN4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="266" mass="28908" checksum="BE401FC51844804B" modified="2020-06-17" version="1">MRCTPLSFSSFPLALRSRFPRATSTRPSRGECAEAHSSRAVGIPDERKGLPPFGRGPLPVVVAAAAGVDRQRGRTCKPRAPLGACGGRGDGGGLLVRRCVRIGRPSGSSRGCDSRWRLQGTSPKKVPRGERRSRTDGRADGFSSPSRSRDGELFTYVPVARGKVLSGKVARSRPRIGKGGGGNSWVEIYKKNSRRSRGRVADCCQLGVGRYLAKMRKVRDHRGTEGVRSIPSTYLRKSHRAERFAAVGMYLGRARATFTCRPVGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUQ5</accession>
    <name>A0A6A6NUQ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_66045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUQ5"/>
    <dbReference type="OrthoDB" id="5405126at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="416" mass="46389" checksum="0FC9EE663947877E" modified="2020-06-17" version="1">MSVPAHLSRALRRRAFLGLQQPQQQQPLRQFSASAVASSRAGTYQAHTLDTLEIVFPFPNNAQILTTTTPDALVTFHESSSPELASLLSSLRSRVVLPRLLNAEQRHAVFSAKHRSRLQHEDFVVALGPPGREQDVRLEPLRAAVDVPPRWASLRAALRLARTDDDWANVFLCAEALEAAGVPLRLYQREVLLRKACEAGRVGLAVGAFRRVGRSGFSLREAPLRAYVFAMVRRHAEAAGWEEEDTRRALGWCEALAEMLEDERHCGGSTSVGLRDPRAEPAVIAPLVELAGVRAERHLGGKDQEGKVATYALRLVHAMKQREKAEIELLPTLKKDPEVSRTASMFERSWYLAQGLPLWHALDLSLRILGDDMPMRKDAVRWKDEVHKLLAEVREGITVYEGSELPGVNSWDALNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUV6</accession>
    <name>A0A6A6NUV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_66848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUV6"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="448"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="666" mass="73946" checksum="0B3DA3C22DF76139" modified="2020-06-17" version="1">MPGTKDADKMIEERIDETKKKQEGKKDGEKTNSQRLLRVDQIYSRKDRQTHFVKTAKSLNKAKQNRFNKTTLVVRRIITSKGMVGGIEVDIKSPGLKEVMANIYEGVEGLHLNKTPPMANPNHFFHALPGLAERRAEEAAKPTPDTTLLADLDIAIEYTLEDFGSDMANLRSLSEHGEITYDLVWALFPPNAIVYTAANQLHQPHALRFLKGEYVGGEEPHYALECRMISHDGQDFGWATMDLKIRPFEGARKVYGLDAFPLESHPEAERVREMLIERGKTYVSLLKPTLKDHRGLAMKWEWTQSGDRIYKFYAPGRVMLDPVAYRQQNASSSLLRPWVPGTIPASSLSPDDLLLCAYWHLGYSFSKKGWGAFPIAQLSDVTWNDEAFARLVMEPGRRSLIHSLVKSHYKGPGEDADSDVTAEGGDVEDGSRGGGTGGFDDVVVGKGRGLVGLLSGNPGVGKTLTAEAVAEITRRPLLTVTAGELGVDAVRVDRTLESTLDIARRWNCVLLIDEADVFLQIRDMMNLQRNALVSIFLRRIEYFQGVLIMTTNRKQAIDAAFQSRIHFQVHYPDLDETSRAAVWTNFLSAPQPLPSTASHTSSAAPATAAFSPGDIAELAKIPLNGRQIKNAVACAMSIAREEKAPLTVPKIRQILDIVTDYAQQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVB8</accession>
    <name>A0A6A6NVB8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1750-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_307638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVB8"/>
    <dbReference type="OrthoDB" id="5321006at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013859">
        <property type="entry name" value="Ssr4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046464">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20497">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08549">
        <property type="entry name" value="SWI-SNF_Ssr4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 C-terminal" evidence="3">
        <location>
            <begin position="257"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="625"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="698" mass="75365" checksum="453B645799502B41" modified="2020-06-17" version="1">MQDPFDGVPHLLLEHLHLTANYNYPTTSTLRSNQAIEYLVNAPRLIRDRVSVSWSYQTTPPDGSLFLEWFPTGNPRRGDKFASDGYIWVDPEQKYAQNIGGYDVEFYVHHQGFRVGESFTSHMRTRYRIAQRHPLPPNSAPPDPSLWLVHYQQQTDPRYRMPVNQLPVGPDVQATMAERRSIETQGQLLRKEFHLHDRSNWPRVEFHGRGPMAAGPGLAQQGVGPSPAKRPRQGPGPQQMPGAAAASAYNAGPDAWLEDEESTHLGDVFDFLTPREISSMRYQQHHEWMEEIFSSPFAISQIQPVDLGFGLPGDLAELTDGLFDAPGPQSWQAVRLPETLDRPAVRSAAERSASNDLPDQAKASEFEKRVAKYVERSKSEIDGLKKEHSKTLAELKRSKMYMTAERKLQKAMEEGDDKASESIPVEVERTLGVRIEPWQDVACIDKGGLIEEEKQPDPQQTQYVNGDSDMPASNGDGNSGELDEGMDPDNTAAGLLDQYGAGSFISTPNTNVGAVGQSRPVSQGPSAMQSPRQTSAGAEAEAGGDAQDESLLMDAMDLDVDMDGLTGDMDAGSKVAAGDDWVIVGDEKMEDTAAKRAPGGGGAASQAEGDGPTEARADAPPPASAPAASAPVPQTTAASTPGMFESAEFANFDNLDTAGDALADYAGGGGDDLGLDLDNSAFGDAFHGTEGEGEGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ8</accession>
    <name>A0A6A6NVJ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_387067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ8"/>
    <dbReference type="OrthoDB" id="5132737at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF2">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="190"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="368" mass="42158" checksum="3120417EE69D6D48" modified="2020-06-17" version="1">MWQRPSSTAEDAYNETASDNADSNNPVDYWRKHLCWPRTYFESDENMDRPFARKKSTSNIRRKSSATSISSSGTTPSDSTSREGKGSIYRDKRFDGLLAGHKSFLKKVLCKELLEAEQPVPQDSLFNDELFEETCDYLVNKSEAMVTREIGLLIHLKILAEKPRPQPDYSVGSDSSSFSEEQHKKLKPFNAYSTTLAGRAIVDLFRLVKREKEINREMLAFSVSHDSRSVRIYGHYPVIKGRDTAYYRHPIHTFDITELDSKDKWTAYKFTKNIYDTLAPNHFRRLCSAIDELPHEHNWDIPPLSEGTGLSQVFDTSVLQEDDNQASLPESQDVTSNTSFSQPRQFRKPREGVLESSSLNKARCFAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVL4</accession>
    <name>A0A6A6NVL4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_66540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVL4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="21593" checksum="FE1607C854BDA426" modified="2020-06-17" version="1">MYWLLLRTVPVKKIELASLELISTGSCLRGPDSTLVEVSLRTRRFRSALGMIQRRSILSRKLSIQIGLCKQTEHTLLCRVALSCDAAGRDAPFRLVHRVIAWQTTLLAQCNLETEKRRKDSTDAIIKDEILFLSAVRWPDLELASAAARLPGDCAREDRRVRKVAQVIGEKRPRGALTGSRRCRAITSWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVY5</accession>
    <name>A0A6A6NVY5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_289035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVY5"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000002">
        <property type="entry name" value="putative tyrosine-protein phosphatase auxilin isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000354">
        <property type="entry name" value="UBA domain-containing protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="303"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="675"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="836" mass="89287" checksum="6E10CD0076111271" modified="2020-06-17" version="1">MDDLSGLDWNASNSNSQQPPTAKPTPNYASLRPSPSLPSSGRSTPLSAQPSGANARPQAPAKSSTQAQDSFSGLLSFPSLKQSNNLSLQQRQQQIAEEKARQAEEQRKKYEQQYGARDHQFWDTLGSGSGKSTPQPGAQPNTGLSGTINKPFARLNQTTSQASPPPQQQSSGQDDDLLAAFNADAPVNTSSHFPIPQSAGSGRTTPAQPTGGLSSASEPVQAPDSTADASWGDDDDPFGLSKLPPRPTDTSTQNATADDDDILGMLGKPVSEPPPKPSPRPTVSTPEPRPAEHNEPESPAGDDPRDKAVAELVDMGFPVEKSAIALAQTESGTNVQAAVRWLLQQAHEEARQKTQGGHQSDHRSRSQTPEFGSERERRPHRGRSQRSDFSSPAWMQGPRNRSGSEQQRSGSHSGVEKDVAQYASEIGTTFLKSANSLWKTGQKKVQKAVAEFQHEGDPSQPKWMRDASPLQDASDRAQGHARDRGAHSRPNVTDEAMMLEGGGGPPRKPRPRIEQRGSSIPAVSPSALSASGNHRVNGSAAFKRGDYTAAHQSYTSALTPLPQTHPVTIIILCNRALTNIKMGDPKAAIADADAALVTIGPSRGESERIAVGGAEGDKEMREFYAKALMRKAEALEHLEKWTDAGKVWREAVEAGVGGAVSIQGRNRCDKASGKAPPVSSTPSVRPVASARKPAAPARPSTNGPARPAASSASSAEAVKKLREANAAAEKADDEKFALSDSVDAKLAAWKGTKTDNLRALLGSLDKVLWPEAGWNKVNMADLVMPSRVKIVYMKAIAKVHPDKIPQTATTEQRMISASVFSTLNEAWDKFKKDNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW47</accession>
    <name>A0A6A6NW47_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LMBR1-like membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_373048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW47"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="198"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="548" mass="60617" checksum="CC0B3407D1D5A5EB" modified="2020-06-17" version="1">MTASAGSAVFFVAALLAICAFVLLLLRHYLPLRPTPAYLLLPVFLALALPASIILLVPIDLATVFTQDDTAGSPKGIWLPPRVVLVAWRITYWLTFALTWIILPLVGEYVDAGHRSPRSRFMYALNANLRYQAIVLGLAIAAGVYVFLTSGVSFASLKALVMALAYAWGLVLAIALMGHGLVALPREMFKQASTSGRLRRAQARAPRVHEKLLDAEDELAEVEDQVRVLSGRKRGTALDFQDWIDELAEGAGVHEAPSAAARGTTNTTAPAVITERYLAELTRRLHRAKHKRARFADEWECLVDMAVEAQAILDAAGSQRLEFSPRPDNSSLKGSHPLSWQSYVSKTWRKASKAWLTPRTRYYLHANILPSISVFVAILAAVASVFLVETEMLRPFSVQQGALIPLTVRMFAPRTEAFDFSKQFVSAFWLCYAVACTLYSVSFVRVWRGRALVRRGTHPESAAWYAALAARLAVPLAYHVGSMLTQSDGAWDRTVFHDFLGRMIDFTPLGEGFSRWFPVFVLVPMMRTTRTEGRAMHLGLAGGEKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW55</accession>
    <name>A0A6A6NW55_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW55"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="54" mass="6527" checksum="4CE972ABBE756DCF" modified="2020-06-17" version="1">MQMRAGRRVFTAFFRREKWNGCRTRPAARSAPTQDVWSNDAAKLRDRMLIWWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWC1</accession>
    <name>A0A6A6NWC1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein-tyrosine phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_288861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWC1"/>
    <dbReference type="OrthoDB" id="271628at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF128">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="5">
        <location>
            <begin position="136"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="248"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="514"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="701"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="760"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="705"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="2">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="355"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="419"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="794" mass="87577" checksum="426A2225B644CECA" modified="2020-06-17" version="1" fragment="single">QVEHVTLWRRGVRCEGTLHLTAHHIIFSYVPPDAAAAAAGGKPAGDAKPLRPKETWITYPMISFCTYRPAPPASRQSPSIRIRCRDFVFVAFHFQDEFSARDAYDSIRSLTCKLGRIERLYAFSYRPQSPEKDVNGWEVYDARQEFKRMGISAKDVDRGWRISNINSTYQYSPTYPSVLAVPTSISDNTLKYAAAYRSRARIPVLTYLHPVNNCSIARSSQPLVGVRNNRNVQDERLVSAIFSTSKPDAESLSSSASTIDLGTTTPNRSSVHLPAGTSGESSFVDAEALEDAATRASNEDAGSKTPPKIYGAQQENMIVDARPMINAYAMQAAGLGSENMENYKSVTKAFLNIDNIHVMRDSLNKVVEALKDTDVTPLPPNRELLVKSGWLKHIKLLLEGSTLIAQQVGIRHSHVLIHCSDGWDRTSQLSALSQLCLDPYYRTLEGFIVLIEKDWLSFGHMFRNRSGHLNSDKWFEVENERVGGGERSSGAGGKALENAFLSAKGFFNRKNDSRESLVDSEPELQATSDQSPATGRASTSNSDVDVTVVTKPKETSPVFHQFLDATYQMMYQFPTRFEFNERFLRRLLYHLYSCQYGTFLYDNEKQRVEADVRRRTRSVWDYFLARKQQFINESYDPVIDDNVRGKERLLFPDAKKVRWWAEVFGRQDSEMNIPASSTATGVPNRSDTSSPLVAALQNGTNTIHSSSRPRSPFPPSAVAAPGGGRAPPAPGVAAAGAARAAAGSGITAGMASMSLGWGLGGTGVGAGARSSPKSRSRSPRVKKGEAAGVEVEMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWL0</accession>
    <name>A0A6A6NWL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_63066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWL0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="64" mass="7612" checksum="714ABC486E45D4FB" modified="2020-06-17" version="1">MPTSFFFFSLFYSFLFCRNSVVSLELAHIYPILWEAIVDFGFVLLISLYFLFFFFFDDAVAVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX15</accession>
    <name>A0A6A6NX15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_65766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2456012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX15"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="124" mass="14433" checksum="35AD134999176A39" modified="2020-06-17" version="1">MAFHVHIGSRNRRRHIDCRNCGSLLTRIILDMYRQAFHALFSFCFIFFSTCQTGWEWAIVHFELVAFGKMDFFCCISFHSPFSFARLPILGFTWIGWWCLSAYGRSLLGCGVGESDEWLTIMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXS3</accession>
    <name>A0A6A6NXS3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase II subunit 1</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">ATP-dependent DNA helicase II subunit Ku70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDY21DRAFT_415730</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ku70 family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXS3"/>
    <dbReference type="OrthoDB" id="3249161at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00788">
        <property type="entry name" value="KU70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01458">
        <property type="entry name" value="vWA_ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000071">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.290.10:FF:000001">
        <property type="entry name" value="X-ray repair cross complementing 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.970.10">
        <property type="entry name" value="Ku70, bridge and pillars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006165">
        <property type="entry name" value="Ku70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027388">
        <property type="entry name" value="Ku70_bridge/pillars_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047087">
        <property type="entry name" value="KU70_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005160">
        <property type="entry name" value="Ku_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00578">
        <property type="entry name" value="ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF2">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03730">
        <property type="entry name" value="Ku_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003033">
        <property type="entry name" value="Ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="SAP" evidence="22">
        <location>
            <begin position="606"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="556"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA; for 5'-deoxyribose-5-phosphate lyase activity" evidence="20">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR003033-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF2456540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="643" mass="72155" checksum="A0218FAB4829F2C6" modified="2020-06-17" version="1">MAEPSDRNRLDEDEGSDEEEEVDDSGYKTVKDAVLFAIDISDSMLRKPPPSDSKKADRDSPASAALKCAYQLMQQRIISNPSDMMGVLLFGTRKTKFHDEHESSKVAYPHCYLLTDLDVPSASDVKRLRNLVEDEEESQELLVPSDEPVSMASVLFCANQIFATKAPNFSSRRLFLVTDNDDPHGGDKAARSSATVRAKDLYDLGVVIELFPISRQEHRFDREKFYDDIVYSTSISDLDAPAPLVPDNQELKSGDGISLLQSLLSSINSKATPRRAVFSLPFEIGPGLRISVKGYILLKRQQPRRTCYVDVSGEKPKLVQGKSAKIADDTGREVDKAEIVKAFKFGGETISFTKEDLAAIRNFGDPIIRIIGFKPLSYLPFWANTRSATFIYPSETDYIGSNRVFSALQQKLQRDQIMGLAWFIARRNATPVIAAIIPSEEELGERGEQIMPGGLWVVPLPFADDKRKNPETTVVRTTDDLTDKMRVVIEQLQLPKGVYDPKKYPNPSLQWFYKVLQAYALEEELPPEDTKSATDKTVPRYRQIDKRAGAHIISWGESLEEEHSGQRGTKRGSDGPDLKLAKRTKTSAPDAPIDEEMRRNFEKGSINKLTVAALKAWAEKKHLDTSGKKADLVDRIEDYFEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY26</accession>
    <name>A0A6A6NY26_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY26"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="11"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="236" mass="27239" checksum="23C8A867ECAAA404" modified="2020-06-17" version="1">MVNGLKDLPTGHPQLYLDIEGVNLGRNGSISIVQMYVLQRRHTYLVDVYTLNEVAFTTAAPDGRTFKDILEDGEIPKVFFDCRRDSDALFAHFGVRLARVLDLQLLEVAGTLRGRVSGLFYLIRACESIGTEDKDEWCRIKDVGKQIFNNGQWEKFNQRPMPAEIRQYCLQDVVFLPILWSVYRAQFDTMSRPTRWARKVIKSSNDRVAESQSPDFKDLGWAMAYVPKDWPVDPEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY73</accession>
    <name>A0A6A6NY73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_393880</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Extracellular metalloprotease that contributes to pathogenicity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY73"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000165">
        <property type="entry name" value="Glucan 1,4-alpha-glucosidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.340">
        <property type="entry name" value="Metallocarboxypeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057247">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036990">
        <property type="entry name" value="M14A-like_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00133">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0843">Virulence</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025436230" description="Peptidase M14 domain-containing protein" evidence="16">
        <location>
            <begin position="23"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="17">
        <location>
            <begin position="133"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="15">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2456484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="434" mass="47736" checksum="F42621D22C0693ED" modified="2020-06-17" version="1">MRAVRTSLALAASLGATLGAAAATSYSGYKVFRLSASTAGSAEVEDIISSLGLATWENSLGRTGVVDVVVAPHQLSAFESRVTVAESSDITTRAPEIIAEVMHEDLGASIDVEGNFAEVEGKKPTVDDTWFDSYHAYDDHLAFLDDLVSTYDNMSEIVTSGESIEGRNITGIHFWGAEGPGKPAVVFHSTVHAREWITTMVNEYMAYTLLTEYGSDADITGFVDAYDFYIFPVVNPDGFVYTQTSDRMWRKNRQEASNNRCLGRDINRNWPYVWDVPGGSSTDPCSETYRGEEEGDTPEVQGLFGLLDDLASTDGLKLYMDWHSYSQLFMYPYGYSCDAEFPNSSEMGTLSRGFTQSLEAVYGTQYEYGPICNTIYQVSGGSVDYVGDVSGADYSFTAELRDTGRYGFVLPPDQIMPTCVETWAGINYLLQNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYE1</accession>
    <name>A0A6A6NYE1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_51693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYE1"/>
    <dbReference type="OrthoDB" id="3937830at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="12251" checksum="E8855C4874312D0C" modified="2020-06-17" version="1">MLTRFWQWFLAVSPPGGQQQGATMVSSPAAQNTPASAVATPAFDFGSMFGYSVREPFGGAHIFRRDVCDDAFPGEGASRNTCTPNDTLCCVRASEPFPQCEQYLGKGWCCVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYI9</accession>
    <name>A0A6A6NYI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_364378</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>prephenate + H(+) = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYI9"/>
    <dbReference type="OrthoDB" id="983542at2759"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000034">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000228">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="252"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="336" mass="36985" checksum="CCABB5ECBBE944AD" modified="2020-06-17" version="1">MYMVAFLGPNASYTHQAARDRFNQDTCVLSPQVTIEDVFQQVQSRVAKFGVVPFENSTNGSVVFTLDLFADIKSRHPDIVVCGEAYVDVHHCLLGRGAARLTDTSLSSKTDSPTSSGQATPTSKVPYPKTPAVKPVVPVKHVKKLYSHPQAWGQCRDFLSTYLKGVERQDVSSTSRAAELVAEDQSGSSAAISSAIAAEVHGLDVLARNIEDSADNKTRFFILKRTDCLEHQPMHRGAKVVDDDQNSFKSLVSFTVNHEDPGSLADSLAVFKSYKLNLTSINTRPSGLVPWNYIFFIEFKGRRENDGATGAVNAALRDLNNVAKCWRWLGSWESEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYM7</accession>
    <name>A0A6A6NYM7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_53882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYM7"/>
    <dbReference type="OrthoDB" id="4226666at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="122" mass="13386" checksum="055EE725D3C253EA" modified="2020-06-17" version="1">MESYDQSPCTPGAFASHDAAFLAKGRTLNGAAELRTVTNPARPCTTGLSRQGRPTASSTTIPGTSILRMSPPNGNAICRAKRKRPLSPDSKRETHQVRKIGACYRCQLLRIKVSAQFRRRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYS6</accession>
    <name>A0A6A6NYS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYS6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="11028" checksum="AAD7EECACF702F6D" modified="2020-06-17" version="1">MGLALPRDPIPASLGPPPLLGAAACPRCHETRRSLCIPENATSLGRYECSATKDERKKLRPPGMARLRDGKPRAATSRRALFSTRRLAERPRGTARQRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZC6</accession>
    <name>A0A6A6NZC6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_386289</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZC6"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="52"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="299" mass="33556" checksum="270A418FDF1FC8AF" modified="2020-06-17" version="1">MDPSHLRGEQYEDEHVHEVYEQIASHFSSTRYKPWPIVERFISTLHPGSVGLDIGCGNGKYLTVNPDIFILASDRSPNLVRIASTHNRPHVSLAADVLSLPHPLRTFDFALSIAVVHHLSTRERRINAIEAILAMLRPPWSSDKTVSGEPGRALIFVWALEQKSSRRGWDEGDDQDVLVPWVVKGGSQQQEKSSRMKQRKGKKGTRGSTMEEQVPQPDAETKPGPRAPSEVSSVPESEGRCNDKDSSKTYQRYYHLYRKGELEEDIETAGGTVLESGYERDNWWAICAPSMLNSYSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZJ1</accession>
    <name>A0A6A6NZJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L23-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZJ1"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="7">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="17432" checksum="28842C59932C547B" modified="2020-06-17" version="1">MGPKKANVGAKAKPSKPQAQAGAAAKATLRGVDSHKVRKVRKSTSFRRPKTLKLSRTPKYPRKSIPHEPRLDHHKIIIHPLNTESAMKKIEENNTLVFIVDVKANKRQIKAALKKLYDVDCLKVNTLIRPDGKKKAFARLTSDVDALDIAATKLSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZT5</accession>
    <name>A0A6A6NZT5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_274230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZT5"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="63877" checksum="6F40CE9778689B59" modified="2020-06-17" version="1" fragment="single">LAPTADDDDADRWDAGGRDSKEETKSSWYLFLLTLTAGGLQISWSVEMSNVSPYLLSLGLSKSLLALVWIAGPLSGTLVQPYVGIKSDNCRIRWGRRRPFIVGGAAATIVCLMCLAWAREIVGGFLSIFGVDTSSTGVATAVIAFAVVFVYVLDFAINVIQAGIRAYVVDCAPTHQQEAANAWVIRSSGVGNIIGFLSGYVNLPQLFPFLGNTQFKVLCAIACIVLAVTVAISCSTVHERDPRLDGGKQGDQPLGVIAFFKSLYRSVRRLPDQIKRVCIVQLAAWIGWFPFLFYITTYIGEIYAEPYFAANPNMSKEEIDRIWEEATRVGTLGLLIFAITTFIASVFLPFVIAPTFKVPIVEAATTLEPALAPATNLTGGHALTATEGSSGDSSSHSAAGSSTQHPPSKHRRHGPHRRRGVQAWLDRQLSKLQIPGLTLRRAWLLSHFVFAVCMFLTFFTHTPASATALVAVVGIPWALTNWAPFALIASDVSKRDAIRRGLVRAPRSRDGALLAAGEDDGADGAADQAGVVLGIHNVAIAAPQVVATLLSSAIFRALQKPRGEPGDDSVAWVLRLGGVCALGAAWLARRVHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZV0</accession>
    <name>A0A6A6NZV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_421823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZV0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="30993" checksum="40A1DFF388A7D342" modified="2020-06-17" version="1">MHPALTILIAILYWLLAFPLLQLLTLLLLILRPLYATIQFLLLPLAYLGSLTLTLLSIPLSLLQKLEPLYIFLSLASLVGLAAGLLLALLVPRLLALLGLADDPAAPPSPTSRLFAAAWPAPAPAPAPAPAPRRPSEPRRSVAEYREGRRRREALRGLERGGRDGWGLSMAKDGFKSYVRKEPCRLCSARLEKGSVLHVASARASSGFNNNGSSQPKPKSALPPLRRESRCDPTAYQSSRRRQVQDLDSRVQNGAHKHRPGPQKPKNPSSKAALGRVFPNLLEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZZ5</accession>
    <name>A0A6A6NZZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZZ5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="71" mass="8385" checksum="747439EA98A6A967" modified="2020-06-17" version="1" fragment="single">MGMAKLLLFPFSITPVRHSYRLLLFGAIDKKFCLRCRGYHPNPARKEESYRSHRMQQCSSSGNRQTNRQHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P044</accession>
    <name>A0A6A6P044_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putativeoxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_363659</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P044"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF119">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="570"/>
            <end position="571"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="672" mass="75151" checksum="67FF663955093C20" modified="2020-06-17" version="1">MTIPDEVDIIVVGGGSCGCVVAGRLANLDHKLQVMLIEAGESNLNNPWVYRPGIYPRNMKLDSKTASFYYSRPSEYLSGRRAIVPCAHILGGGSSINFMMYTRASRSDYDDFGMKGWKTEELIPLMKKHETYQRACNNRDLHGFEGPIKVSFGNYTYGVMQDFLRATESQGIPTSDDLQDLDTGHGAEHWLKWINRDTGRRSDSAHAYIHSTRAVHQNLHLVVNTKADKVLIENGRAAGVVTVPTKPLHPNQLQSKTYRARKQIVVSGGTLSSPLILQRSGIGDPQKLRKAGVKPLVDLPGVGLNFQDHYLTFATYRAKPDVESFDDFIRGNPEVQKRVYEQWNVNGTGPLATNGIEAGVKVRPTEQELAEMDRGPFRSFRKGWDAYFKDAPDKPVMHYSVISGWFGDHMLMPPGKFFTMFHFLEYPFSRGWIHVTSPNPYETPDFDAGFMNDERDMYPMVWGYIKSRETARRMDAYAGEVTGMHPFYKYDSAARAQDMDLATTKAYAGPDHISAGIQHGSWSRNLEPGKAASPNFLNSNCQEVREDLQYSEDDLRAVEEWVKRHVETTWHSLGTCSMAPRNGNNHSRDGNTRVEHGVVDERLNVHGVRGLKVADLSICPGNVGCNTYSTALLIGEKCAVLAAEDLGYSGSALDMKVPNYHAPREITGLARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0V3</accession>
    <name>A0A6A6P0V3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_371759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0V3"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="295" mass="31789" checksum="0B1557459A5F3780" modified="2020-06-17" version="1" fragment="single">SDDRTVKVWDTSSGACLRTLEGHSHVVSSVAFSHDSTQLVTASDDRTVKVWYTSSGAYLRTLEDHSDIVTSIAFAYDSTRLATASYDHTGKVWDTSSGACLRTLEGHSSMVSSVAFSHDSTQLATASYDRTVKVWDASSGACLRTLEGHSDGVTSVAFSHDSTRLATASDDRTVKVWDTSSGACLRTLKDHGDLVSSVAFSHDSTRLVTVSDGRTVKVWDTSSGAYLRTLDTGKILYNLSFDSTGSYLYTEIDTIVIRGLGVSSITDIAEPKRSQVQTSGQELVKVHKYVSGLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Y2</accession>
    <name>A0A6A6P0Y2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Y2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="93" mass="9794" checksum="C8F052EE6FB9BCCA" modified="2020-06-17" version="1">MYIQNPRCALRRTKSAVNQPFLVFPPLLESDASPRCLPLDATSNSSQKLMQHRASGFGPRASAGQPTDPAGYCHCPSGSAPRGLHSGTGGRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P157</accession>
    <name>A0A6A6P157_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_30119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P157"/>
    <dbReference type="OrthoDB" id="5426734at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="74"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19873" checksum="5D2488404FC5D4A9" modified="2020-06-17" version="1">MDPGNRPTTRGQDAHADANAPQQPSNMSIEGYEAGDTRYPHAVPVEPNPSSPQEFRNNPEHATIEVHSTPAGSQEDSITFVDNVSVSYILPWQRCKTYEGMREMVEEVYSRENSRRYGRSTSERSSQDENTTKEAYPFGGKYDLVGPGGQVILPSAWEIIVRPGWVVGIQQWDSRSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1F3</accession>
    <name>A0A6A6P1F3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_16587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1F3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17377" checksum="E4C66374BAD6D22A" modified="2020-06-17" version="1">MPRPWLFPRARPGDRSNRRVETHGDKCMAHRSVDRSSRMTSPLEYASKQVGPIRNVSPCVRFRIDGEPSDNKRGLMQADDTTTKSHPAPSVQTEKRLARTCFKTCMIRTRAGCAKLDVEDPSKGFGRGFLGHANAKEEAASHGKSLDHCSVLRTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1M4</accession>
    <name>A0A6A6P1M4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_19436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1M4"/>
    <dbReference type="OrthoDB" id="5295250at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="58"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="223" mass="25830" checksum="272400FD0FA9672E" modified="2020-06-17" version="1">MASQATDRDQGDQTLVARIGSSTDRSEWLHRFVEGLDTDDIRILKHILESKTLQSDPLADKARLPDDVLSRIIMFLSPKDICRAQMVSRRWLAVFRHPEYLRPFFRRWFSLKDPPLLGEAALAADQGANTYAIAELKMDHIKRFQELRPCSDSIILREFERPRCTAHSDMLAFVWDDRTRISVMFLRKKNEAFTVRVPGHHKVENLLLGDELMVASTATRWIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1X1</accession>
    <name>A0A6A6P1X1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_302815</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1X1"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF3">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="9">
        <location>
            <begin position="33"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="8">
        <location>
            <begin position="171"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="362" mass="38358" checksum="78C8832FA369AF33" modified="2020-06-17" version="1">MALNATMRAVMWEGIPYSVTVASLPIPTVQTGTDAVVQVQAAAICGTDLHTYHGVYGSSNAPWSLGHEAMGVISEIGDSVTFLNVGDVVVVPDLMESGHLNLEPQMGEAIGLGTDFGLPGGCQVPSGNENASYPDPTDFLFLSDIFATGWTALDYAGFEPGDTVAVFGAGPVGLLSAYSAILRGASRVYSIDHVESRLQMAASIGAIPINFVETDPVQEILRLEPSGVRRAVDCVGFEAVNADLELQENIIVHQMVAVTGFRGGVGQVGVWDSAGNTTGTPYAATLSPNITFPMSDFFNKGLQFQAGPVDPKVVAPHLVELISNGVAHPSFIISSEISIEDVPEYYSRFDQHLETKVVIRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P273</accession>
    <name>A0A6A6P273_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 13, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_385290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P273"/>
    <dbReference type="OrthoDB" id="5544375at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012471">
        <property type="entry name" value="DUF1690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07956">
        <property type="entry name" value="DUF1690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20362" checksum="DE682D70EDA0A65B" modified="2020-06-17" version="1">MGANGSKEASNGSTHVFSADAPVRFSNELVEQLQQSPESDTTRARATELKLQSRLAAELEKLQADASSALTSALNSADGPSSPSPSSDSTASPASPSLVEKAGSALGLVSSADESRPTRDAVAAELAALRRSLEARKEAREPDGGVRAARDDVVACLRAKDRRPLDCWREVEAFKREVGRLEKEFVERVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2L2</accession>
    <name>A0A6A6P2L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation machinery associated TMA7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2L2"/>
    <dbReference type="OrthoDB" id="3052842at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28632">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="7480" checksum="AEFD23F6BD6F7E23" modified="2020-06-17" version="1">MPSGQGTGTNPIHNKKPRKQQKDMDEDELEFKKKQQADKKAREEMAAKASGKGPLNSGKQGIKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P373</accession>
    <name>A0A6A6P373_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_284534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P373"/>
    <dbReference type="OrthoDB" id="8059989at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818:SF3">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="329"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="802"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="892"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1068" mass="118254" checksum="03FA2FB30B3EF39B" modified="2020-06-17" version="1">MAYVLSLTPQSPLKRSFSDTPYLTPTSPPVDDGSSCNTVLQPISANASARSPVSPSGSLLSLPVSTKTRHNENTPPTLTPQSLRSLVDSLANVQKSQRHFGHSPRKPSWGTDISPPPRYNTATPSIQGPVCEPLRDANTDHKFSTEDFGEEDGTLYNPRQRNDTPFGPPFGPIAESENSEDDSENLNCFRQVPTSPGMHYDPSPFKRWMSALRRRNLQKNDAVHMHGDNWGLETPTTRFGQAISSPIESGHRKSESQGSSVGFITAVKSASITLASTSIAPFSARTPVRGRRRGETRSSGISGHRPSSDSMTGDFGPIMDEQAWLRSVQRRKILEELIETEENYIDDMKALINVYFTLLASSQMANTQSRISIRRNVAEILELHEDLLGELHKVVPNAEPSHGDSNKGPGTWARKHKSRHTRWHSADIPARRSSQRKNRRVRHSLDYNQHSDWHCVYLTADTHTVAEVAKVFNKFALRFFAYETYHAHYNAMNFDRESTKTRVPEWERYERGIEALSGSIIAANRRAFGGKKSMTFQDLLAKPIQRVLKYPLLFADLRKQTPVCDDPEAYGEVDKALSRLQVTASEINNAVEDPRTRTLIESTWRLQDRLVFEDRDCLAPGTVLLRLLGHAILCGVLHVAFQGRGGIEGQYMVCVLFRSCMLLAVMNKGSAACNVVATIPLLTCRIQEADNGKGLQCHTALYTWKLAFAHECQLYEMIMSACSAIEEQQWRGHLQARIDAESHDGSQGEPNVANMFSSISMGIKPAGTTLGSDVSVNRRNSIHRAATLGAKATIHQVIIKNTQAQKQPDGQQGAPVGRSHSHMTTNTIPTLAPRRGERVRLENALADVWTRDILPFPGMGQRRPENPIRASANSVMRKLSMASLASNFSKRSNSYSNGGENSSKSTREPNQCQRQAKHRKGSWGNTSSRGSSSRPPPVDFHNSPARFLPAGIGLERPPRRASRFRGALGESSSIERMRESARALSFNGAILQRIDSAQALELFRSPTPTQRPAPVVESGAAFAKEGKPESVKSMPKIGRQPTPARGGSPATTGQKRQHRGRKLFKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3G1</accession>
    <name>A0A6A6P3G1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMP46 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3G1"/>
    <dbReference type="OrthoDB" id="59229at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012882">
        <property type="entry name" value="Fmp46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28071">
        <property type="entry name" value="REDOX PROTEIN FMP46, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28071:SF1">
        <property type="entry name" value="REDOX PROTEIN FMP46, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07955">
        <property type="entry name" value="DUF1687"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="150" mass="16560" checksum="3C34FA533D9FE9CC" modified="2020-06-17" version="1">MFRRLFKEHGTKDVVTLFHSPMQPASSRVLTLLKQTNATAASTATEDQMSSHDEHNKEQRMDFELDVTEAPPTPDQLKSILEYLPRESDVGKIVSGAKGLEDAVKLVGSKPDAFVRPLTVDWNSGKLVVGDDKSAILAMLRALPKETDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3K3</accession>
    <name>A0A6A6P3K3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-lactamase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_340648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3K3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052926">
        <property type="entry name" value="Metallo-beta-lactamase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13754">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13754:SF13">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G07630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="334" mass="35780" checksum="D2FFA05D44F896CD" modified="2020-06-17" version="1">MGLTEIDSLEIAVIVDNELDPLSPSCNPAVKLGGGLKDPSEGAIIDRGGRAKEMRMDHICCGAHGLSMMITAIKGGSRHTVLFDTGPEEEVWQRNAHRIGADIAAIELIQLSHWHRDHSGGMLRAIRMINSAKSADAPPVIADLHPSRPDYRGVMGPIPISLEADPTFDEVVAAGATLVKSAAPHGVCDDMFLISGEIPRRTAYEQGIRRGIRFSAETNAWSDDPLISDERLLMVKLKGKGVVVFTGCSHAGAVNASRHAVELGDSAPLYAIVGGYHLADAERDTIDATVKDFKSLGPKILIPGHCTGWRAKCKIEQEMPGCMVPSFVGSRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P414</accession>
    <name>A0A6A6P414_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_341186</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P414"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="268"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="581" mass="63421" checksum="724FDBE52EC0567C" modified="2020-06-17" version="1">MRSPAASFRACSRCRRSLRVFLPEPFKRAPLCPLRGQQRRANTTSSQARPPTAPKAYLDIKHIRQNPGLYEQNCIDRNYATLSQYPWRIIKLHEQWLNMQRGEGRRLRERSNKIRRLLKLGTGRGRTNGQNTEDASAGEEEARTREELLQEAKALKVELARVEELEKGIQDEIGRLAWELPNLTSGHTPLGETPTVLGHINEQLGTKLRQQETLSSPSFSADPSTLLGGTSRSHTAISAHLNNVLDFPAGARTSGWGFYFLRSAAALLEQALIQYALQEAMARGFVPVSPPSLVYAHIAEASGFRPRDQSGETQIYSVGDVDGGNNGEGGGSSGKTPPLVLAGTAEIPLAGMLAGQTVRPESLPLKMVGVSRCYRAEAGARGAETKGLYRVHEFTKVELFGWAMPPTADESSASADGNFDTSASRSSSIQAQTPAEAIFADILSLQSHILTSLNLHARLLELPSADLGASATRKLDHEAYFPSRAAAGLSTFPSSQEHLGWGELTSASLCTDYQARRLGARVKLADGSLVFLHSVNGTACAVPRVLAALIEQGWDADRGMIWVPECLRVWMRGREWVGEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P458</accession>
    <name>A0A6A6P458_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P458"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="53" mass="5634" checksum="6533FF944561A187" modified="2020-06-17" version="1" fragment="single">RPSPRRRGKTRLRCAVGGAQPQGQAKLMRQASALASGRRALIRPHSGLGLLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4P4</accession>
    <name>A0A6A6P4P4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_362397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4P4"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050334">
        <property type="entry name" value="Molybdenum_import_ModC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43514:SF4">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="162"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="438"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="878" mass="97064" checksum="05B4B6764298F0D4" modified="2020-06-17" version="1">MWSSGRHTDAGNGRWTSAYRCARRQGRGGAQRSAPARLRQHHEAREARPRARRAMRVPRPRRHPAKPPSKPPIVRIASATFYRHHPAAVPPPSTPGGLGHHGAANPPLFPNCSFTLQSRPVYYAPELWAVLSASSAAATAFFEVLRGQHHCAPQGARSYPFLSHPDIVKRHGRALDPLTAIKYVGFDAQRGGLGGSATRGAYLSQRYESHREVDDFSVRAYLDGHTQLNMDERLWAREKPPERLLARVVDQLRLRDLLDMPVSSLSNGQTRRARIAKALLGEPELLLIDAPFMGLDPPTAEELSGLLYNMAFAREPRVLLSARTPDQVPEWVTHLVQLDADYRVVLQGSRYRTLAKILNSHLVKGTKGLSHKKRMFEKVLQEGADAESLGLKYCMKSDDEATDDVAPDRVVSKDGFPERDQRRPTLGDPVVEMEGVKVQYGDQTALGGWNQPVEGSPEPKQGLWWTVRRGQRWGIFGPNGSGKTTLLSLLTSDHPQSYSAPMRLFQQSRLPKPGAPGLSYFDIQKLTGHSSPEVHTYFPRQLTVRQTVESAWADTPLSKPALDYAADLKVEACLRWFDPELNPSYAPSAVRELTQFPSASASLRAVQATKIRRALEAEAADPARLDWADALRFADLPFAAQRVALFLRAVVRHPDLLVLDEAFSGMDPAARNKCLLFLAHGERRTVRSEMVDAGEGEGAGERGGRERGLVVAESFVSRFGLAKMEGLLDRQALLVVSHNMVEVPGCVREWLCLPEPGKGAPRFGRLHGALELDPSGWRTIWGMNASLVLAIASSLAAADNGACEHNTLYCGKTLVDTYDWTYEEIRDQSGARTIAWNPNVIRETLYRCDETTKALGGGLDPMYPCTDCVDKGGGDWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P571</accession>
    <name>A0A6A6P571_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase, variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_340644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P571"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000014">
        <property type="entry name" value="Probable acyl-CoA dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000027">
        <property type="entry name" value="Putative acyl-CoA dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="48"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="165"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="277"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="440" mass="48209" checksum="33F79C3E24DE5FE7" modified="2020-06-17" version="1">MLLKSISPCLSASSHLPAVASQWRTVLQRPRSFSVSCRRPIMEMSGFTPEQVMVREAVSKICSNFPDEYWAERDESGEYPHELHASLAKDGWIGIALPEELGGAGLGISEATMMLHTISESGAGIAGAQSVHANVYATQPVAKFASPAQRQKMLPKLIKGEWRACFGITEPSTGLETLKLRTTAKRDGDFYKISGQKIWISSAQVAQKMVLLARTTPLKEITRPSKELSLFFIDFDKTAPGLDLRRIKKMGGRAIDANEIFFDNYRVPADSLIGAEGQGFEIVLHGMNAERCLLAGEALGIGYAALKRATEYARERVVFGRPIGQNQAIQHPLAAAYMNLEAAKLATYHAARLYDENSKDSSITQYAVGVACNSAKYLAAEAAFTACEQAVLAHGGMGYAQEYHVERYLRESLVPRIAPVSKEMILNFVGEKVLGLPRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5A2</accession>
    <name>A0A6A6P5A2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADPH--hemoprotein reductase</fullName>
            <ecNumber evidence="9">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_410761</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="545"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="11">
        <location>
            <begin position="982"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1363"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1464"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1383"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1404"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1487"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1576"/>
            <end position="1597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2458613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1635" mass="178763" checksum="1FAACC5630361A1E" modified="2020-06-17" version="1">MSEASCPISGIRSQLGRGCPASQRKGPRGCAFAAFQPNAGGSTMFADDPAEIQRLHEQERRTINEMLMPKAYPKEVTKSLKNADELNPPDDDVLAIALGAPARSVLARAEQIGPRTGWKDGYLSSTHGFCPPDPSDAPVALRATPGRVWSDLCERMPGVVARGNMRNAILALPLVHGTADVIPDRALWAATVCLGILASVYRYEERNDGNDGITVAPPPGTFRGLTGDEDDEEPETKGIPRNIAIPLRQVCTRMGRPLPHLTQFDVSIYNYKIRDPTSVHPYVARSENMDLRWPVFNDRGEAMFLLCMAEVHGAFVPGVELLTRCQEAVMNRDTEGLIQELVKLKAVIDQLAFVFHKISVNPNSGENFANPVEWGQRYAKFSAPLSKRVPALSGLALPLFLTMDAFLGRTKYTSFLGAEAVHLRRWLPMNIRAFIAAIENHYQVPNYVKEVNDPRLNGVLEGLVESYAGERGFMGTHRYKVYGFLEVVAKTGRTETNGNAGATDSVGRPWEEVHKTLSESMIERLDPYRGKLSVQPHEMRGTFEECRFKARILERANIDNDPTRATGMVTFDLQGTGITFQPGDRLAIMPMNTRQEVIKVAAALGVEDMMDTIVPVENGSEWARFTKHLNQVSRSSIGLTVGDILKRGHLAPLTKDFVMAFHLALRASSRTVLKLLSTEEWPIRASLGDLLQKAIMDVPSAVWDQAFSLSDLSWLSKLIPLEVPRTYSISNYSGELLPSMIDLTISRVEMKPSPLLEPAKDALPSYGVSSGFLNPNPQIMPCDHLDDDEVLIGLSRPINFQLPSSTTVPIAMFAGGSGIAPFRGFWQSRVANGIGRNVLFMGTQSRDKFLYEHELRGLVQEGSLELYTAFSRDRRGLLFDPSTRELIERDMDPRYIDATIVEQGRLVSELVMSKNQGGLGGHLYICGSVSVYETVMSGIRAAIYKYQAATKSSADALLATAFAERRFMLDIFMTPRPISFTMPTISLADLAKHTGHRKGSRMWIGVHGGVYDVTDFLDIHPGGTLIVAASAGLDATKTFDDLAHTSNPEVSSLLSKYFIGHLQQKPELQRLPEISQLYDVWHQYLRTSVESLTTLYFEANNIMEDSKVWFSGGLFNIGGVRKFYQFQSRLMQNGFSTLFGAQLQEIYLKLSFTLANSGAPNVRLPDIIGTITRAQSSPDSTTAAKEIANVGQFVCNASGSAQFHENGILRYAQTCTEMDIAFLEQIRDEICTGMDAFGIFTSASEETTTAGKQMRLAAFLLSVLERIAKRLESFYGSLAGESMYRPELELNPARSRWNNLRRKIRDGSFFVLAHTLEFSFKGSEDDNGLEDPAAYFRSNRNRTATRAAEVDFTDIFQQAQRALQRADVHSKQQQQQQQKGRAAAHDRAVPAEPIRRRLADNHTARASQKANAPSSFEAGEQRGALSRMTAFIDSNRAAINRLSRLPPGLDIEQLMADYASVGGGRGANASGAEVPALMGGPVLSPPASDTSSQRTRSSSQASSTASSGRAAAARAHAHAQIAASAGAVPDMPPPPAPPKDDGLQRRRGPSAAVAPDMLAPTGSTTAALRRAPTLPSSPRASRVGSASGAAPSVAGSVKSNASVAVMPAGLNTRKGLRQDGVVEGRNVNVGLRGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5B1</accession>
    <name>A0A6A6P5B1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_340815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5B1"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="221" mass="24245" checksum="293EB9EE24988E75" modified="2020-06-17" version="1">MGSTMEPYAVEPEVPVVKILLLGDAGVGKSTFLSRLTLGHNAAETGTAGPGPPPPYELPRLRDLDQPFVFAVTLFARPYRFEMYDTASPTNYTLLAPDFLILCYDVTSRASLESLTTRWRRELETHFGAAVEARVPVMVLGLKRDLRRDWTDEERLALKGEHVMPQEGLGAAQKMRCDAYAECSAVTGELCREVLEDVTKMAAKTTTENGAKTPGTSCGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5B6</accession>
    <name>A0A6A6P5B6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="3 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_318513</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 14"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5B6"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.870:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000009">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="484"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="801"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="801"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="834"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2459205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="971" mass="106688" checksum="CE04A6CDE63E814A" modified="2020-06-17" version="1">MSSIVDAVLHFDDLPAAPAYNDTQQHSSQQRQVRSSSRPRGPPSDSAGVNSDAEGYGDDEVVGARGTTQRPRASRQDIPRVVDPTGETLSVRFEEFLESYTEEPTSSGVPMSSIQTTDKYYVAQIHGLKEYGLSTLYVDYNHLLQHERGVVARAVASEYYRFLPYMIRALHNLIARYEPQYFREHRQPTSTSSVATNVSVAGTASQSQPGPLSEKNLNQQTDKIFALAFYNLPTVTRIRQLRTSSIGQLLSISGTVTRTSEVRPELLLATFTCEVCNSVVPNVEQTFRYMEPTQCPNLTCGNRFGWRLDIRQSTFVDWQKVRIQENSTEIPTGSMPRTMDVIFRGEMVDRAKAGEKCIFTGTLIVVPDVSAFRVPGQTPKAVRDTAGRPRGADVGGSGVTGLKALGVRDLTYRMAFLACMVTPDTSTAGGQQLNGQAGNILASLNQVAPLDPSATGEEAQKEYLATLTAAEIDDLRSMVHKPNIFMRLVDSIAPMVYGHQVIKKGLLLQLMGGVSKVTPEGMALRGDINICIVGDPSTSKSQFLKYVCSFLPRAVYTSGKASSAAGLTAAVVKDEETGEFTIEAGALMLADNGICAIDEFDKMDIVDQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPVGGRYNRKTTLRANVNMSAPIMSRFDLFFVVLDECDEAVDRRLAEHIVGIHALRDEAVAPEFSTEQLQRYIRFARTFRPAFTPEAKRTLVDKYKELRADDAQGGMGRNSYRITVRQLESMVRLSEAIAKANCVTEITPEFVREAYNLLRQSIISVERDDVEVEDDEDEGEAEADGDAPNGHGPDHEGDSPMADADGGAAMGADGDAGGASSTPAPRRKERTKITYDKYMAILNMLVRRVSADQRSEEDGVEEDDLLIWYLEQKEPDLHSQEELETERGLAKKVLKRMVKDNILMPIRGEGLVDGTEGAPREVRTMYVIHPNCAIEEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5D2</accession>
    <name>A0A6A6P5D2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_384957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5D2"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="19"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="342" mass="36264" checksum="B067AB154BF5EC0E" modified="2020-06-17" version="1">MASANVPQTMKCVCIEQTGGPEVLQLKEMPVPTPKEGEVLIKNEFVGVNFIDIYFRTGLYPTPSFPSILGRECAGTIAALGPTTSTTTSLRVGDRVAALTGGGAYAEYAVAPVRNTAPVPPGLSTDNAAAALLQGLTALAMTRESHRVEKGDYVLVHAAAGGVGLWLLRVLRALGARIVATAGGEAKCRLVRETAGEALVAVVDYKKEGGYAEVEKVVKENTPGGEGVICVLDGVGKDTFDLSLGCLRRKGTMVSFGNASGAVPPLTITRLSPKCLKLVRPQLYPYIATQDEFEGYVVQLFDMMLKNKINTNMHEIYPLAEAARAQVDLGGRKTTGKLLLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Z5</accession>
    <name>A0A6A6P5Z5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerases I, II, and III subunit RPABC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_283163</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the eukaryotic RPB8 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Z5"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000191">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005570">
        <property type="entry name" value="RPABC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03870">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000779">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00658">
        <property type="entry name" value="RPOL8c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="141" mass="16173" checksum="E4ABB8DD8C6E8528" modified="2020-06-17" version="1">MSDSQLYEETFSITAINNQKYDRVSRISGTSSDNTTIMTLDINHELYPVAVGDTLQLVLASTLNLDGTKPEKGWREFKREEANLSDHFDYVCHGKVYRFDEGEGDMIKVFVSFGGLLLYIEGPYKKLTPLRIDYVYLLMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6A3</accession>
    <name>A0A6A6P6A3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_338070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6A3"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38886:SF1">
        <property type="entry name" value="NACHT-NTPASE AND P-LOOP NTPASES N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38886">
        <property type="entry name" value="SESA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025559694" description="Fungal N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11541" checksum="7956BA4AADA7C358" modified="2020-06-17" version="1">MPVAFGSVSDIFAVSLLVKGLIVALHETRGPSAEYKQIARKLLSLDKTLLKVELLIGTHSSTPGTIQTCRAISAKVSDCREVLENFSKRTNSYEEGLSICVSKSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6H5</accession>
    <name>A0A6A6P6H5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_188944</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6H5"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="45"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="492" mass="54506" checksum="478D57B8356347D2" modified="2020-06-17" version="1">MMSDEEKGSGKIPLDDQNGSVQEPDIPPIDHEAERKLVRKLDLCIIPMVMVLYLFSFLDRVNIGNARLYGLEEDLNLNSSQFQTAVSLLFVTYILSELPSNLVLKKIRPSRWISFITTGWGIVATLTGVCQNYGGLIACRLILGALEGGLFPGMTIYLTFFYTKSELALRVGYLFVSAALAGACGGLLAYGIGHMDGVQGMSGWRWIMIIEGLPTFVLGIASWWLLADNYETAFYLTHEEKHLMQIRRERQIGHTTSAQKFHRSDVKKGLFDWKIWAFCFGQFGVDTMLYGYSTFLPTIIRGIDSSYSSAIVQVLTIPCYALGAIAYLIIAHFSDKQQMRGVYAVAFGIISIVGYGMLMSDSGSGVHYGGCFLVALGLYVCVGLPLAWLPTNNPRYGKRTTATGLQLSIGNCAGIMSSFLYPSEEGPRYIRGHAVTLGMVGFAILVYAFMVWYFSHVNRRRLRGGEDAKVAGMTEEEIAEMGDSSPRFIYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6H6</accession>
    <name>A0A6A6P6H6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_282198</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6H6"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="1"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="395"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="489" mass="54617" checksum="75FA16AED804158C" modified="2020-06-17" version="1">MKFAHIFQDHLTKDGFPQHWVDSAISYRQLKKCIKRVEEELTALGLDADTLTALLKSVEKGTTSSTHEEEENKPFEYRLSRASSSAPSPPTATLNTPPSRRPRSSSSPQFVPHLLFAVDERTGQPLDARLAPETKAYLHELAVRQGLTDVRVLDTSATTASAASSRTSSTSPSWRNGTDAAPAIRMVSVPLHSDTLFFAQLWRELSGLASLQAAEQSELFSAVAALRDKVAKVADPARGGGKLLGKKLAMHKSDLPVWQRIFASYVEREVFFATGEVEHGARGYEEARRRFEGWVADLKREGLPATRGFKRKESADALALFVALNRRLLANLLFMDLNRAATAKILKKFDKRTALGARPGYDVGALLARDVTQAVCAAVAQELLPAVPQLTDWLCPVCYAVAYRPIRLRCKHLFCIRCVVVMQRTRTARCPLCRETCVLEADTSTIDWELGRWLKMYFPKEVHAKHKDNLRQNSVEEYGEEYIDKCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6J6</accession>
    <name>A0A6A6P6J6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HRDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_370135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the exosome component 10/RRP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6J6"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071044">
        <property type="term" value="P:histone mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071040">
        <property type="term" value="P:nuclear polyadenylation-dependent antisense transcript catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06147">
        <property type="entry name" value="Rrp6p_like_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000059">
        <property type="entry name" value="Exosome complex exonuclease Rrp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.80:FF:000001">
        <property type="entry name" value="Putative exosome component 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012588">
        <property type="entry name" value="Exosome-assoc_fac_Rrp6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045092">
        <property type="entry name" value="Rrp6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049559">
        <property type="entry name" value="Rrp6p-like_exo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124:SF47">
        <property type="entry name" value="EXOSOME COMPONENT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124">
        <property type="entry name" value="POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08066">
        <property type="entry name" value="PMC2NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="10">
        <location>
            <begin position="499"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="646"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="750"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="758"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="828"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="855"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="899" mass="99068" checksum="D51A20A249B44094" modified="2020-06-17" version="1">MDNSTTDPSTDFATFRDTLTSALLATTRSTTALTTADLPFHRALDPSVGASLDAQNARLAALAGRFLGSTGSSDGSATARRSGSKEVVGSTFGSGRSNISLADTDAIDNAWTAVVDVIDSLLEKADACLDEYTGAVKKTGVGIGAEQAAAASKASVTHIPTIYNPSRMVKPQTLFEHVPRNDETAPFKPLLTAKPYAMVPLENCCNTVTDEEGMQHFQHPYRTEITQYRYPPSMYHKSEPIPFKDYETTSATFVDTPEGVAEMLSELKEAKEIAIDLEHHDTRSFAGLLSLMQISTRDKDWIVDTLQPWRRRLECLNEVFANPNIIKVLHGAYMDIIWLQRDLGLYVVGLFDTYHAARTLGYEGAGLAFLLLKFADFKANKKYQLADWRVRPLPPELLDYARSDTHFLLYIFDNMRNELIDRSTKKLDASATATVDPSSAETTTYPSWAFKDSDRLEQVRRLSAETSLQTYEHPFYDAGRGLGPTGWLRALQRANARFSSEQVAVFRAVHAWRDRVARTEDEGVNWVLPQHALFSAAREMPEDRAALFATVHPVNPVLRRRADEFVEVVRSAKEEGSREGAPDSAALLIEHDRAKRERWATRNEVAVGAPKQAPAEATEAAPVPARTAPSFTSFITAPLRTLASGFWGRSDQAPPTASRPAQPNERKRKRDYSTMAAGLGPSDRPTPASDVSLAIPLPPLTAQIFRSPAEEQEQAKGVVEPGARAEHMYVKGASARRNEEDGDDVFVVKALGGGRQKRGGDTAQKDASYDDNEEAVAAPSPPAPFMGEEQGAFDEGADEILLGEPEPKRRRGGDKKEKKSEKKKARREQRLQREMEERNAEPFDYAAAPSVLHAARGEHERGQRASDMPFRDAEKAGEGELKGLPRKQKGKAGRSAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6N2</accession>
    <name>A0A6A6P6N2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_370342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6N2"/>
    <dbReference type="OrthoDB" id="2107880at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061671">
        <property type="term" value="C:Cbp3p-Cbp6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037653">
        <property type="entry name" value="Cbp6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250:SF1">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="135" mass="15242" checksum="8E1849B32F15C151" modified="2020-06-17" version="1">MSNSSIPRHYARILSRWPVDNLRPHLAFQTVLRTRLAASSSTTTTPPTAPPSSGPPARLQPHHQTPAAADLRAINALYTLLEDRYRARYPVSAAFRRPRANPTYYDDLAREIGEAPGRGWWARVALKVKGFVRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6P3</accession>
    <name>A0A6A6P6P3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_262989</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6P3"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46077">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TOPORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46077:SF1">
        <property type="entry name" value="TOP1 BINDING ARGININE_SERINE RICH PROTEIN, E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2459655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="304" mass="33691" checksum="71B821533E205C0E" modified="2020-06-17" version="1" fragment="single">CVICLSPVSERAIAAPCNHASFDFVCLASWLQERATCPLCQAEVRFINYDFRSPDDIKTYRVQRHHDRRGRHHPTHLLHHHRPRPARHLREPNPPPAASEDAAVLRRRHVYARGLYSLYVGANRISRYRSRVTAQDIAASAELQRRAAAWMRRELRVFEFLDGGGSAEDGEGEGEGGATGGYGGNTGAGAGAGAGAGAATGVGRRRQQRARNAEFVLSYALAVLRTVDLKGAEGAAEDLLADFLGKEHARLFCHELSAWLRSPYTSLADWDRHVRYAERLPDRFTREGEPVWDGGRACSGDKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7H4</accession>
    <name>A0A6A6P7H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_176427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7H4"/>
    <dbReference type="OrthoDB" id="26203at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="56"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="506" mass="55828" checksum="06755D6B4C6FED7A" modified="2020-06-17" version="1">MANLTELRGACPPPFLDVSQFSVDGGFTAGRFCAPTGQATCCLPCPATDWIYPRGFVTWYKVAESINGLGLALCLFLLISYMVLPIEKTRRHYLSVCLIIGVIALALGFVIPLGVQPPQCYDEITPNDMYTSLTCAWSGAFIIAGGLAIDVWIFIRALSMHLQICWDVQPGKKFFYVAQGLGWGVIATLFTATITVTGVSFRFGDACHVNSENSMKDFWGPLLAIAGLSTIVQLATFGYCINVYIKNLWSDEKTETTNSSGLPSYTSSLRMQSARAVYRRVRKVVWLQWRGIMIVVFILVDVIFFSIVFVYLDSMENAHLKKADDIEPWVTCLVLSGGDKEACTDIAQKSLVNQPTVVAILLMLALAGVQCFLLLARLSMFSGWYHWFKEKTVRKNEFVSLDAASREARTYELLKVGSPTPPPAFSPSTLASPPGTYSPAGRNTPDYFGKDVQREYRPSSMSFSAPRPPSSQGRLEVDLRSAQARGGLGLHPPVMESREDVMSNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7K8</accession>
    <name>A0A6A6P7K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7K8"/>
    <dbReference type="OrthoDB" id="3799394at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025684106" evidence="1">
        <location>
            <begin position="21"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="142" mass="14575" checksum="B7463A06044B12FB" modified="2020-06-17" version="1">MKPLVSVLLPITALALACRAATLTAQPKPEPTQPALFSCGGLYQWPCPNGFKCVDNPLDMCDPQNGGYDCPGLCVTDVADDEPAPFCMGITGAMCPEGLVCVDVPGDGCDVDQGGRDCAGVCFLGEEAGATMTASATATAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7S5</accession>
    <name>A0A6A6P7S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_299640</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7S5"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07628">
        <property type="entry name" value="BAR_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06863">
        <property type="entry name" value="PX_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000035">
        <property type="entry name" value="Sorting nexin-4 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000042">
        <property type="entry name" value="Vacuolar targeting protein Atg24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="14">
        <location>
            <begin position="10"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="349"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2460066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="438" mass="49870" checksum="8A79910541ED4E68" modified="2020-06-17" version="1">MDSQDFNEGRLECTVTKPQKENDGTKDAYVSYLVSTQVSTHPQPGSTTASCARTDFKSFQRPEFSVRRRFTDFVFLFKTLSREYPQCAVPPLPDKHKMEYVRGDRFGPDFTQRRAHSLHRFLKRLTLHPVLRRAALLILFLESPDWHQTMRSRPSRGSSLSDSGGGASSGVFDNFTDTFLNAFSKVHKPDRRFIEVRERADKLEEDLGHVEKIVARVARRQADLDADYGDLATQFQKLVALESGVDAPLTSFAVSVDTTSKGWKGLRDATDQNYLTSLRDMGAYILALRALLKTREQKQLDFEGLTDYLNKAAQDRDSLASQHGYGGAGLGASAFLRSKIEDVRGVDHEQSRRERVRKLELQIERLTREVDDAKTTMEAFDEQVVKEVADFERIKAVEFRDTLGDLADAHVDFYKSTIDTWERFLQDMEKERAAEESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7W2</accession>
    <name>A0A6A6P7W2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_384458</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7W2"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000130">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="174"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="225"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2460050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="250" mass="27103" checksum="DD1678FEECC2A67C" modified="2020-06-17" version="1">MSPPAIIAPSILSADFAKLGKECSDTVNNGCDWLHVDIMDGHFVPNMTFGAPVVTKIRPHVERPAAAYGKGTFDCHMMIAEPKRWVKDFQKAGCDLYCFHYEAALTSTAADSPAGTSSETTSPKELIRFIHAQGMLAGIAIKPKTPVDMLWDILDNPEKQELPDMVLVMTVEPGFGGQSFMAEQMPKVTALRERYPDLHIEVDGGLSEKTIDQAADAGANVIVAGSAVFGAKDPAEVISRLREAVETRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8F0</accession>
    <name>A0A6A6P8F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_267273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8F0"/>
    <dbReference type="OrthoDB" id="5300823at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052841">
        <property type="entry name" value="PMP_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="236" mass="25334" checksum="04A32782FA5B4A3B" modified="2020-06-17" version="1" fragment="single">VSSSLPDEVVNCLQNARFLHLATCSANTPHISLMNYTYLPTGSPFSPYPSIVMTTPPSSRKTANLQSNPLVSLLVHDWVSHRPPTLSQSPASQHQQQQQQRSASPPPPQGAPRSSLANLLLGINTAALSRISATINGEARLVDPDTPEEKWCKDMHLANNTFDTEAGGGSTSDTFGTSPPAFGHALFPRASAAGESEVGDGGRGCFIEGEQVRVVVVRIRNGRIVDWKGGVRDWEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8H4</accession>
    <name>A0A6A6P8H4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Outer spore wall protein RRT8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_317097</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8H4"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005619">
        <property type="term" value="C:ascospore wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30305" checksum="687EA737F0783523" modified="2020-06-17" version="1">MADKAKEIILDDTRDAVGLTKAAVRSGKWFYPIKGTIYFLTHGSIRQHFTKRLIPTMSIGLLTTVAMFAFTYVPQVVVMALFNGPLAIVSTVFLVLSESETLAMLVSRSMFLDEALADSFDELTDAHHQTLKTRAIELHGNASPTHTPLLARTTARLARLSPRALLRSLLYLPLNFIPVVGPLLYLARRAATAGPAYHARYVQLRGMDAGEKKAFYARNRPGHVALGLTAVLLEMVPVVGVVGVFGSAVGAALWAGEMEERRMREEGEDERKKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8T7</accession>
    <name>A0A6A6P8T7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lipoyl synthase, mitochondrial</fullName>
            <ecNumber evidence="10">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lipoate synthase</fullName>
            <shortName evidence="10">LS</shortName>
            <shortName evidence="10">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_281136</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="10"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8T7"/>
    <dbReference type="OrthoDB" id="3231at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000036">
        <property type="entry name" value="Lipoyl synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="165"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2460192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="434" mass="46700" checksum="D79929752F18E42B" modified="2020-06-17" version="1">MATAIFSHSRARAPAALPLRQFLLSAFSARSLATVPDAPPAKQSPSSSSASASADAAPVPPSPAASAPRRPQTRFADKLNAGPSFSDFLGGGKEEEHALTPDEALELKTATVNGKKITRLPEWLKTTAVPGGDQYKKIKKDLRGLGLHTVCEEARCPNISTCWGGSSKSAATATIMLMGDTCTRGCRFCSVKTARAPPPLDPHEPEHTAEALRRWGLGYVVLTSVDRDDLPDGGAAHFAETVARIKAKAPSMLVEALTGDFAGDLDGVRKVARSGLDVYAHNVETVEALTPGVRDRRASFRQSLSVLEAAKGAREGLLTKTSLMLGLGETEDQIWDALRELRVIGVDVVTFGQYMRPTKRHLKVHEYVTPASFERWRQRALDMGFLYCASGPLVRSSYKAGEAFIENVLRKRGVQRPVEGFEGVGIEVGSKPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P945</accession>
    <name>A0A6A6P945_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_267158</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P945"/>
    <dbReference type="OrthoDB" id="1905920at2759"/>
    <dbReference type="UniPathway" id="UPA00896">
        <property type="reaction ID" value="UER00863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046951">
        <property type="term" value="P:ketone body biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000071">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="15"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="335" mass="35483" checksum="87E7F508A7525819" modified="2020-06-17" version="1" fragment="single">RTYSAPASSESNDIVRIVEVGPRDGLQNEKGTIPLRTKIELIERLAETGLDTIEAGSFVSPKWVPQMANSSEILEHILKSPPASKSPIRYQFLLPNMKGMENFLSVYSSHQPATTGGSSAAPEIELSIFTAATESFTRANTNCSIAESLARFQPIIASAKQRSLPVRAYVSVALGCPYEGPDVDPQRVASLAVSLLEMGADDISVGDTTGMGTAPRTRALMRALHAAGVETQDLALHFHDTWGQALVNALVGLECGVRAFDGAVAGLGGCPFSPGATGNVATEDLVYLFESLGARTGVDLDKLAGVGEWVSGEVGRRNESRAGKATLAKLDRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9A9</accession>
    <name>A0A6A6P9A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_369466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9A9"/>
    <dbReference type="OrthoDB" id="4084551at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028000">
        <property type="entry name" value="Pma1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14610">
        <property type="entry name" value="Psg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="267" mass="29465" checksum="C0C278CD873F7775" modified="2020-06-17" version="1">MRVSVPTSSSSDDNDDEDSSPSTTAAAASDASATPTNTAAPLPFSDSMVECSDPSTGPFCLPHNASDVYVGDTYYVTWDASMFPTNSTVRIALNFANDTERQAFQTAKLPKEYGYTAIEMKESYLQSFDRFNLTFLLRNYAADADADSSWFDGPLVQLQHRPPRHYEPQTVNKNPDKLSLIIALPLVLGSLFIVVCGLYFGMRKQRKIGLGNIMGKRNKGYGIGKSRRQRLGLGKKGAIRLEERDGSAGFRSSDRFRDEDSLEISRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9G5</accession>
    <name>A0A6A6P9G5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_384129</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9G5"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="10">
        <location>
            <begin position="350"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2460544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="707" mass="77998" checksum="31360D4E5A4D2CA9" modified="2020-06-17" version="1">MSDTIFQPITTDDIPSVVKNKGGHPVEKVGIVDDDKPIQTNKFYANLFLGSQAGCVFTQPYVLQWCKGSGSNAKSWGVAVAHSSEGDITFGEMIDGAARFYLRPLGVWSIILSAAELGEDTRLTTDSHGPFSVNCNLAPDEGKDNILTLPMVQGMGFVTGIYTDATILLQSGVLFREFSVVGNNGTTWKFRVTLENNIRWLIYVTPESLGTDDILLTMEGPTVIRGPKGFTGVVQVAKFAGDSAGDQVYDEAAGAYAVSGSVSADSEGNYELAWAKQGITTKSLLMFALPHHQTSFDGETLQARTDIVLQTTVKGKATAYLADTWGLSERIPTEIGFLPWSPSKRYSEDVSAEARDLMKQTGTDELSQDFGGQTDVGSMYFSGKGLAKFAMILIATHDIVQDLDLTKSGLDKLKKAFDIFVQNKQRNPLAYDTVWKGVVSTAGYDDVGADFGGTLYNDHHFHYGYFVYTAAVIGYLDKDWLSRENKNWVNTLLRDFANPIMDDPKFPFSRSFDWYHGHSWAKGLFESGDGKDQESTSEDVFAAYGLKMWGMVIGDSNMEARGNLMLGIQASVFQTYFLMTSDNTTQPPEFIDNKVTGILFENKVDHTTYFGANIEYIQGIHMIPLGPASPFIRTEKFVTEEWERYFDNGRADEVEGGWRGILECNHAIIDPRAAYKFFSQPNFDKSKLDGGASQTWYLAFAALLGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K1</accession>
    <name>A0A6A6P9K1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 69</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_280048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K1"/>
    <dbReference type="OrthoDB" id="194289at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021836">
        <property type="entry name" value="DUF3429"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15887">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15887:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11911">
        <property type="entry name" value="DUF3429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37509" checksum="00F6D0A9E0636EE2" modified="2020-06-17" version="1">MLRAGPSRLIRGVAGATLHTTRPTPIRATRGPQLASRLCTESLARPRPAPPILPGFRPDPIASRAHARAAFHASKGHGKDKEVDSPLAREKLQPTPETVSTTSTTTRVFEPVDDKKDPQMMASIMSDVQTIKETFSLSDVPRQAYFIGLAGVLPYLATSLSTVYCAWEINHATSTGFGYLMSAQSAELLLQILEPLQVGYGAVILSFLGAIHWGLEWAGYGGSQGYRRYAIGVFAPAVAWPTILLPVEYALITQFVAFTFLYRVDTKATSSGWCPPWYGIYRFVLTFIVGTSIVVSLIGRGEIAERMGRLPSPAQRIREFQEAGAQPLEEGEEGRTQALEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9P9</accession>
    <name>A0A6A6P9P9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_335692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9P9"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF242">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="124" mass="14426" checksum="384E509234366649" modified="2020-06-17" version="1">MVRYQPGQKFDLHHDWYPTLQRLKDGRRFNRIASFFVYLEDDCAEGETYFPYIETGNLQRIPDERKFHVHEDGGIAFPPIAGNAVFWVNLLANGTGDMRVMHAGLPVVEGLKTAMNLWPRRYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9U6</accession>
    <name>A0A6A6P9U6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_336048</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9U6"/>
    <dbReference type="OrthoDB" id="1847590at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.310:FF:000001">
        <property type="entry name" value="NSA2, ribosome biogenesis homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="262" mass="29875" checksum="EDB21C0C22A0FB53" modified="2020-06-17" version="1">MPQNEYIERFQKQHGRRLDYEERKRKRLARESHKQSADAQNLRGLRAKMYQQKRHKEKIAMKKAIKAHEERDVKGSGAGDKDDGQPLPQYLMDRSDQTRAKALSSAIKNKRAEKAAKFQVPLPKVKGISEEEMFKVVKTGKKTSKKAWKRMITKPTFVGPDFTRRPVKYERFIRPMGLRYKKANVTHPELGVTVQLPIISVKKNPQSPMYTQLGVLTKGTIVEVNVSELGLVTAGGKVVWGRWAQVTNNPENDGCLNAVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA79</accession>
    <name>A0A6A6PA79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Up-regulated during septation-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_361598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA79"/>
    <dbReference type="OrthoDB" id="5569911at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056703">
        <property type="entry name" value="DUF7801"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25078">
        <property type="entry name" value="DUF7801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="2">
        <location>
            <begin position="163"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7801" evidence="3">
        <location>
            <begin position="781"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="994" mass="104323" checksum="10CE2B36B6DDB8DC" modified="2020-06-17" version="1">MPEPSRTTNLPSPYDGETLTDATKEQYFGFPPTPSSHYPSVQLNGVDTLSYGSSAGGGGAGNYNNAYANNGYDTYSYGSSNYNAAPAPLAAAGGPAPSGGPTSNGASGAGVQSSSGGGGSYFPPADALLRDSGSLGPSGGGGGSTARQRLSAQLDASDPVALHLLVETALGDAAGYAVLSFDEVEGLKRERGTLGQRAEGLRKKLALETKVRDAAASLKRLGKKDSGPGGAPDSEAELAESEKKCEGLARELWGLESRVNEVEGRLLRHTAGVLQLSHGQREERDGSGLVNGAVGERGMYTMDLGRTEGSRAINEDMFDERSLYRLPENLDVFMEAIRSGAGVKAGGGSSARQGQPAMDDAHLKDLAVRLESFNTRIRDLIVQARLSNPQEYALPPQAGDLTLPLSGGQAASVLDPQLEFMDAALANLSGSLAGDRDDTRARVAALNQAIYDVLAQGQDAADVDEYGDPVAGPPPPPSSSQADGASLASELAYAEDSLETLRTRTQGGSASGLGPASGKAAEYEAALLDLWGQIGATDDGGGNSNTNSMMFGTAPAPSALGPASPVSPSSPRSPTEPFSLPAFVHKVQRLHARASAAREQMDILRRQIQQQRELNSASDAEKEAKVAELDAAAQQAARERDDALRRLDDALRAHQQHELQQAGALDAAATLDEERAARRRAEDARDDARDDARIAQAEAEARVAEADERATEAEAALADQRQALEGARRDLAGAAERVAALEASRDAATGQVAALEARLGEATEGVAALEARLGEAGARADGAERRAAASEDEARGLEADVVRLTTEVALAKAELDGAYGSRAERAAEAHKASAASAEQELAGLRRERDEVAGRAEALKAELAQLVGEFEELTRAGVEAEREREGLERLVDGLRDKVEGLEGQLSEERVRWLGVRSPGAQTEGAGAGPGGGREMTSMMVLRNEFKKMMRDTRAENLKTLRAEQEERRKLEALVRQLRREQAPGKSGLSQSMTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA83</accession>
    <name>A0A6A6PA83_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_402659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA83"/>
    <dbReference type="OrthoDB" id="3563649at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="10766" checksum="210FA01B296A6FE1" modified="2020-06-17" version="1">MRTSRIARAERAAKDAAKDAKKAEKEAKKAAKEARKVASATPDAEEAPAGKKKGGWKRKSAALGTDVPEPNVKVARTSRTQAAEDETAPTPWRAPVARMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBV6</accession>
    <name>A0A6A6PBV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_331950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBV6"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="157"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="116"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="398" mass="44184" checksum="38F93A95DE00CCF8" modified="2020-06-17" version="1">MGIEERPKKRKGGVTASSRSKKLKPDLNSSAKPVKDPKEVEASKVKASKASAPSRMRAVDFYDSDHSNDEALASDIAAADFAVKNAALAEGAAGSEEEAEDDQTAALLKGFESSGDEADLEKEDDGLPLDKVPNVPKAKKVSKPKASSNDSSNQGPRVIYVGRIPHGFYEHQMRAYFTQFGDITRLRLSRNRKTGRSKHYAFVEFAHAEVADIVARTMDKYLLFGHLLQVRVIPPEQVHPNLFRGANKRFKAVPRNRIEARHLRYGMVREGWERRLTREEARRQSKLEKLKDMGYEFNAPTLKAVDQVPSKKAQPAEAAEAQEPKAIADKPADEETLSLGAEEKDPEAVKVTETKVMKPSKTSKSTVVEKTKVKKGKMEDGATKTKKAKKVVTKQMRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCM8</accession>
    <name>A0A6A6PCM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MT-A70-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_334528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MT-A70-like family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCM8"/>
    <dbReference type="OrthoDB" id="61116at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829:SF4">
        <property type="entry name" value="N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="260" mass="30138" checksum="D6941F07820C32A7" modified="2020-06-17" version="1">MRIDETVDLVDNMDIDKMLEEPADDGSQPGALVAVWITNSYHSRQAVVGKYGLFEKWHVEFVEEWVWVKVTTSGEPVCPADGKYRLPWEVCLMGRRMKEPKTIDEINAAAAASCGKYRQIKRRFIIAVPDVHSRKPCLKSLVEPLLQKDYRALECFARYLVEGWWSWGDEAIKFSWEGHRVPMRPAEDYGELKRKRKKGKHKRLNRDQRKENESKEGQSKIMETEEDQNTEGEILGEATENEMIGDEATENEVMEDVIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDN0</accession>
    <name>A0A6A6PDN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_277319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDN0"/>
    <dbReference type="OrthoDB" id="5300331at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF2">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="264"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="711"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="760" mass="83966" checksum="293610198FF39D25" modified="2020-06-17" version="1">MTPASPAAANKEKEGRLKRRTWLPGGHSRHASKAEENRPQAWIYSTDGKRTPYDLGPMLNAQPVPELWDDNGDTKVYLYPRTSGKGPSFRVNSDIYASSAFLTELLYGRIYSSATVSNPGGKHQQQLEQGTQNLSLRVPSTPPMTPENRPIDAESSNDSSKGSRDASDLAEPERREIDLFLPLKLSTDGAVHSPVSPSQPQFSANDLDTLLTVRNTFAFLVGGSLVATERRPTIFHIFMKIAELLDVWKFSNLDASTYGEAAASSFDTYVDELQLDNVSSSHEKTIEGIVLGERMKSVKLYNEAFVHGVGKYEELLKLDSPKFPLISAVTRSRMERASMDLHIRIKNIETRLLDFDFPSVFSGIMNSKTADERKVVRFEQWKSAFLATRKHFMSYYKHKYGSWPPKASSKKNDLETSGLNRLVLKDLYHDFSQLYDLLVDRKSLTTRTSEATIPDDDEVGDPIHRSLRRVENEYDHSSPPVQPPIPFDVPILPSLVGTRAGYGADPKKDAKARHKKLKSDEVNAVLMASHNQDAAIHSPCLDSFYEFERKSAHGRTVDELCEHRVGQWIFLYVVLQSLPMLVEDAPGVRWSRGVEYFLCEPPRSGIPWARDPDGSGAGGGVKRSWYGIAGSSGVVSLPSDIVEHGVEGVYRRSHAWRRAEQWSAHSEVLGAAVNEVFNMQAGPLLQPSDSRSSSPGRAGGTRSNRESVMMLGLEALPLPAGVAPPGGASQSRPQSSGDPSKTFDAIIGSAGLEGGKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDV8</accession>
    <name>A0A6A6PDV8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_330284</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDV8"/>
    <dbReference type="OrthoDB" id="2587363at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF5">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025660509" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="34"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2462020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="220" mass="24076" checksum="44F2B17D14C4875D" modified="2020-06-17" version="1">MRYAQLLAFALAAIQWVKADDDTPAHGEEESEEMGPVAFMWPEDREWSASDDNTAPCGSSEEPGERTQFPLTRGALALVIQDDSWNVDVSIAYQNDPSENSDFETLITTRIAELDPGHACYSVPDPPRDVIDGTNATIQLRYTSDFDTDTNETFYACADITYVSSARFDTEIPCFNVTSDNFTASDDDEDEEDAAGSLRSNTGTVGLVAGFVALGSWLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE05</accession>
    <name>A0A6A6PE05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_330752</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE05"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="126"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="12">
        <location>
            <begin position="523"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2462206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="591" mass="65586" checksum="66BD76041BCBABDC" modified="2020-06-17" version="1">MARTASARPLGLASSLTAPALPSARRPFSAAARPSSLFRSAARPASARIPASARASIRPAFRRAYADSSPAPVAESKPKKRFRGFLRWTWRLTYIAALGGVAYLGWGIYIMRNPAEQAMPDPSKKTLVILGTGWGSVSLLKKLDTENYNVVVVSPRNYFLFTPLLPSCTTGAIEHRSIMEPIRNFLRHKKVAVKYYEAEATKVDYEKKVIYVNDESEVKGEISSTEVPFDMLVVGVGAENATFGIPGVREHACFLKEVGDAQKIRNRIMDCCETAIFKDQSPDEVKRLLHMVVVGGGPTGVEFAGELQDFFQDDLKKWIPDITDSFHVTLVEALPNVLPMFSKQLIDYTEKTFKEETITIRTKTMVKNVTDKYIEAESTGPDGRKVVEKIPYGLLVWATGNAVRPLVKDLMSQIPAQKDSRRGLAVNEYLVVKGTENIWAVGDCAIANYAPTAQVASQEGAFLARLFNQMAKTEEVETELKALSEKQEKAPNGEARNAVLNEIKELQKRLRRVKTIGPFEYSHQGSLAYIGSEKAVADISWLTGNLATGGSLTYLFWRSAYLSMCFSTRNRVLVCVDWVKAKMFGRDVSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE34</accession>
    <name>A0A6A6PE34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_9938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE34"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="117" mass="12675" checksum="6586D9E2F6774FEF" modified="2020-06-17" version="1">MALGPRSGYDIGGWDPLDAAAGPRSGQSSLPLPASSHQSQNTSPETHHCRHQTVQRIRSRGRTRNCSALPCPPLTRAVCGRKLGPSTPYQARLLPGSGSFSFLLTSFGRSRANRFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEC8</accession>
    <name>A0A6A6PEC8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_11744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEC8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="42200" checksum="FA97FA543C65C074" modified="2020-06-17" version="1">MPPRHPRSVPWSKTIPTKLAWCVHQTVFNRYPGGIVHQAPVMEIGEAWDQAERDWAAMNRREKEAWKRRKDIDCRAAFDEYMRERTRVRSESYVRALLYGAGMHRVNVRVLRNLHAGQQGGVRMALEQDLNYVCTIWGIHSNQVLQQQYLEVIVFVYEHRLHRLPDAVRVDWQRKLSRNQWAYQPCTDSLFPASNRRVNVANPNVQNLPTASNFSEWPPHRFDRNHPGVPDWLRGENSDWHFRRVICARNSGRVLLFLEYDDTFVIRNRRVVKIATHWGHDPDNEEGPRIPTPWPGVPPEIRVYRRLRTQGQYPNDVTLECFGHALGPDRFGIDNVKAWLFLEFAQHGSLHWFVHDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEK9</accession>
    <name>A0A6A6PEK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_272271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEK9"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="14008" checksum="9AF541A03E94708B" modified="2020-06-17" version="1" fragment="single">TGGMVAAARWHVYARERSEAEVDEAARAPELVPEVNAEFVRAHTESVAAVRKEVMGGKPHYLLGQLATFPMHERRGAASLLVRHGCELADKAGLPCFLEASYQGRPLYERHGFETVKEVPFDCTPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKT5</accession>
    <name>A0A6A6NKT5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_359497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKT5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="53" mass="5942" checksum="BD267D9F7B4880AD" modified="2020-06-17" version="1">MKGCSINKTLREELSTSRRACEENRLGDCCHVNQLRTQQYGGCAVSLRDISIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKW1</accession>
    <name>A0A6A6NKW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001714">
        <property type="protein sequence ID" value="KAF2452279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKW1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="18380" checksum="A09BF96613F4503E" modified="2020-06-17" version="1">MARRAGRRASARGVGGGRRSKRRARYVRAADVILGFPPAAGSPPGTPLRGEPQPASPTPSLRAHGHGDRSRSRGAGGAGRIEEGREERASPVRTKARRRDSIRHATRHGEEPVPPGGAGRVGRSVRREKGRTAPGGRGKSARHGQESIAYYVLRKEEHMARRGPQDGGELTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL02</accession>
    <name>A0A6A6NL02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sodium/chloride dependent neurotransmitter transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_294829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL02"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11554">
        <property type="entry name" value="SLC6sbd_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="659" mass="72710" checksum="6F661154D08265B5" modified="2020-06-17" version="1">MDKAIHAVKKIGAWFAPPPAKSEDDGRDQWPSRTAFVLASCGGAIGMGNMLRFPSQVFNNHGLQWFIPYLMAIFLIAIPCLVLEIAIGQAYRGGCVIAYNNMSNRLKGTGMGLIYVGFIVVVYFVPILAWIMVYFRCSFTSPLPWTGRVEEFYMQDVIANPDPIPGNFSADGDSVVDYTEYPATGVLGEIAGWCAFTWFVVWLCMFRGVGLTGRVVYFTMGLPIVMAIILIGRSCSLENAGRGVKLYFGSWDSSQLGAGKIWQTACGQVFFSTGVGFGYYTAYASYNRKYSNAVQDAVIIVCSNCSFETIAAFAVFGVIGFLGMNPDEMDDIGSFTIGFLTYPAAIVEMPGANFWAVLFFFTLMLLGISSSFAMLDAVMTLIMDSEWGGKGKFSRPVVATTLVIASFLLSLMYCTEFGYYLMDGVDRWLNNITLVFVVWSECVAATVVYRYKDVVSEVGLPAYIAYNAGYFGGQVFGVAVAHAVIPAAGAGLGFGLYVLGFVVSLLIAKTPDQKAPSIWNKNVFLSRLWYLGFYQGNQLRHDLNVIVGAGKNWNIPNWWAPILRYIAAPILAIVFSFAYPEFYTLRDDPVYIFGFIIAHFGILLVGIGFILPKWFDVFVPAERRNEGYKTYAPNVLMGTIEAESDDRLEASSDEKVPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLT3</accession>
    <name>A0A6A6NLT3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLT3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="15982" checksum="6FB7FCA139EF9979" modified="2020-06-17" version="1">MYVDLRVFAFEQVLIRMQFEQWTYTFDNDFALEFFKSLSSSRPPIQLAPARCCFRCTSIVAANRSLNLSNVSVAGKNCQVCALLLRAVKRHCNDDERNVQIIRRWPDSKIRSDGRQTLRICSDSGYCLQLTRAGQCRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMM6</accession>
    <name>A0A6A6NMM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_382443</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMM6"/>
    <dbReference type="OrthoDB" id="72772at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="719"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="753"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="831" mass="87866" checksum="BB2D6D82650EECAD" modified="2020-06-17" version="1">MGDDAEFPLHQELPGGGRRERPWLYPYNRRLRHLQGITIRNLTLLPSQSTPHRSRGHTIDDDALPYTLTTPAKALALRESKKLEHSRSSSDLGSMAERSSGGKSKLESKGKVQGKGKGAASTSSQGLQDGYSGGVTAVESAPAEPGARDGAEQGSGMDGGGDSSGGTPKPTTPPRPTFTKMRRRSTMEWANASPLSRQKKLEDVTSGRMADVFFSLHVDGMDQPVYVSEVAPKAMNPSFRFFDLGPCGPSVTRRDELTVKVWTKTETMDGWQYLVDLSVNLRALQFIGKELPLFRHPLPQNCILFHLTDGIYTSFTDLPISASLERSITDPLNNTSAARGGEGGRDLPTVPTSSYDALMRLSTLDTCIQDALATRDHLASQLATLVSDNAEALSLTQRAVAEADDSAKTVLDAVTHERRRVETVRRRRNELRARNAGRREAMRKGIEAQQLVAEAMEEGWAKARDGEKAMERVEEEMVGQRRRVCEELLQIYPVEPLAAAKGAGRSGSVGGAGAGDSRPSSRGSGTSRGGNATGSSGDALAFTIRGLHLPNANLDDADPDVVAAALGHVAQCVHALSFYLSAPLPYPLTPHGSTSLIYDPISLTPSTSSRPATSAAATSGSGAATAAASRDAASRTYPLFARGALSYRFQYAVFLLNKDVDVLATRLGLRLPNIAWTLPNLKYVLFVATAGKGEVPARKAGGIRGLLARGREARSLLVGEVERRGSGGSEGSPLGAGRAAGNLGNALAGAVGRLSPGAAREPGTGRAPSAESGSAVAITSARPQDTNGSGNGSADGELVRSGSARRSKDRAPYMGVAKTAEVQGRGLRSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMW1</accession>
    <name>A0A6A6NMW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_375180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMW1"/>
    <dbReference type="OrthoDB" id="4851849at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="36896" checksum="29BD2A6A085819CD" modified="2020-06-17" version="1">MLPPNTASPNRSIWKTVGQNQFENNVDRLSKTNFIPEPHVLPKKDWPKQSGDYALPFDVEKQLADDFAFIAAYDYGVQYVTVATVQASKDSPNSTTVRLAANEGVNERAKDAISKVLAAMQRCASKELKRQTCAEEILDVVVKLNQNRILGRLDSRYFKPNYMCKKPNLAQLPIRLKQQIEDFVPRRRSRMREGVQELSEEVNQFHQYFNQLEYSTVKSERVGVLMLLVKQAFKITRDGFSFPSRLSQAVLNIRQRDISEITKIANYWRISQELSNISRSYRRFFQDVGLEALPRYRPFRSSGKESVFEDDGDNAKGFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN73</accession>
    <name>A0A6A6NN73_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Karyogamy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_424840</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for nuclear membrane fusion during karyogamy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the KAR5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN73"/>
    <dbReference type="OrthoDB" id="5311848at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000742">
        <property type="term" value="P:karyogamy involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048288">
        <property type="term" value="P:nuclear membrane fusion involved in karyogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007292">
        <property type="entry name" value="Nuclear_fusion_Kar5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012:SF1">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0415">Karyogamy</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025540057" description="Karyogamy protein 5" evidence="14">
        <location>
            <begin position="25"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2452917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="48495" checksum="9AD52DC9F85C6791" modified="2020-06-17" version="1">MHLPSLHALIMRFALLVFFVGVLAADNSAPSGDSSNLSDLEALLKGNTLDTARNFVFAEAVRVLQKMEPASYCAHKATTDLVSSCQSLERPDTSPDFNFDKLIETVPSVYAVRLAACELSEAGVILPPDCDFIMSTTFVGFSSLPASDQEAVHEKLATSLKVCLERLSHYPQSWTSYSNARQSSVLICHACRSAIEEQELNDRYRRMAEMGASFSESLAQQMSAYMAELREDAEVVQANMRELKLTQEVIVESTNHVLHEIHRAYAKSVASINQTFKTVEEYGLDLMDNMDHSQAALAKSFEDLLDTRNEIQSTSEYVAANAAEVTIAMDEVKKSLPSLGRHLEALAGLGGLAIVMFGLYLVGGKVAGYTAIVVVFCAGAVMSLPTLEMQQYVPEIKGRLSKISAAPEDALMGFVAALVVVAIGASLIALFKGFNKHHGANGGKLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNC7</accession>
    <name>A0A6A6NNC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_404591</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNC7"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="446"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="130"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2452864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="810" mass="92120" checksum="E0A4D8A47BD88D83" modified="2020-06-17" version="1">MPQDSPRRDPHNSHQRRSPNKPRDRNRDRDRDRDRDRDRDRDPDRQRQRERRRRRGHRATDSAGELLAPPPPPAAPGDRRDSAPGTPKRGSRGRESGTEGSGSGSGSGAGPLSAGSLAQLDALNARRGLREFDGTGIREQRRWEERQKVREKKGEGGEEGEDGGLGVEGRRERERERKEFEERKRILLAEHAGGAEARKGRGYTELEREERRKRRKSHGERERDRREKKKRVISGTLLEKGDSDDILEYKLGRRGGAEYSDEEWERRRKKKRICIILAVIVAILAVVIPVAVVLSNRNDTGSDQTSSSSDDAPAPSNSNLDSISQSDIPDSAKGGYLDPFTWYDTTDFNVTYTDATVGGLYIMGLNSTWDDDERANEHVPPLNEPFDYGDMPVRGINLGGWLNLEPFITPSFFSSFSTRDGVIDEWTYCTKMGQSKCAENLEKHYSSFVSRQTIVDIRNAGFDHVRIPFGYWAITTYDGDPYVPKIAWRYMLRTIEWCRQNGLRVKLDLHGAPGSQNGWNHSGRQGPIGWLNGTDGDLNAQRTLDIHNQLATFFAQPRYKNVVTMYGIVNEPRMVDLDTDDVITWTEKAIDVIRGNNVTAVLVFGDGFMGLDNWQGKLQGHDNLVLDVHQYVIFNTDQLSLPHAEKLNFACKGWTRQFERSQDRETGFGPSMCGEWSQADTDCTKYLNNVGIGSRWEGTLNTGNETTQVLTPQCPTDNDPTCSCDKANEDPSNYNDAYKKWLLYFAEAQMDSFEVGWGWFYWTWDTESAVQWSYKRGMEAGILPEKVWDRTFQCSDDIPDFSSMGLPEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNL3</accession>
    <name>A0A6A6NNL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_417276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNL3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2453276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22592" checksum="C47827B018D2395A" modified="2020-06-17" version="1">MASGPPSPIRQLPTPGFVALSSAKKIEEENIPTYEGGDYHPVDIGEAFNSYVSIEYCGKRMAPIIIDYFDVIGPNWNPQILYPSPNNVHPNIEEDSTPAQIEQGKHKRPIARKILEGRTIHNSRSLPGQPAIADLGEAKISHQMHKGDIMPRIYRAQEAILGMGWASKVDIWAVGIVTWGLLEGSHLSFAKRNRIPNGEQHLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNN7</accession>
    <name>A0A6A6NNN7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_388196</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNN7"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000409">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000076">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="136"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="83"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="293"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="637" mass="68980" checksum="E4C2CDA1A705E577" modified="2020-06-17" version="1">MNGASDIKKAAINKAKQVAQAANGGGNGGKKRRKGTDLKPIITTEGQQAAAATGAAQATNAAGQAMQGGYYGATASPQLTHQKAYTGGNMNRSPSPSSSSADETAENTADEEDSEDYCKGGYHPVSVGEQYKDGKYTVVRKLGWGHFSTVWLSKDNTTGKHVALKVVRSASHYTETALDEIKLLNKVVQANKDHPGRRHVVSLLDSFTHKGPNGNHVCMVFEVLGENLLGLIKRWNHRGIPMALVKQITKQVLLGLDYLHRECGIIHTDLKPENVLIEIGDVEQIVKTYVGDDDAAPGLSKKEKEDNRNGRRRRRTLITGSQPLPSPLNASFSHADLGAFPGSTQSLNKIVNEKADASGAPPNTPGLPAGMSMVEALGIKNADEAEDKHKQREKTAARRSDLLTKDVSGLDLSSSASSSTGAEMTADSSGAGGEDLGGLETISVKIADLGNACWVNHHFTNDIQTRQYRSPEVILGARWGASTDVWSMACMVFELITGDYLFDPQSGTKYGKDDDHIAQIIELLGPFPKSLSLSGKWSQEIFNRKGELRNIHRLRHWALPDVLREKYHYSIEDSKRIADFLLPMLELVPAERANAGGMSNHEFLDGTRGMEEVSLPVEVGSKGEGIEGWATEVKKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNU4</accession>
    <name>A0A6A6NNU4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_145784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNU4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="133" mass="14168" checksum="1F2C67015B6E64A8" modified="2020-06-17" version="1">MHDLLRQGLVRFGFVVDIMCGSSGHVMFGAKGNAGPGSAHSVRRLQSTPRPQPRMHSACHRVLCDARQIRLAPSRIGAGCRKGSASKSGTPRPASRPRLPAFVRNRVAGARRRKGCVRFASGQPTGTLADEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP69</accession>
    <name>A0A6A6NP69_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-oxoacyl-reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_292885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP69"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="278" mass="29710" checksum="E09D12B6EA374E46" modified="2020-06-17" version="1">MLSTLPGVALVTGAASGIGRAAAGAFVEAGCSSIGLLDINETGLLETVNELQELSASTLKVNTYVCDLTSAHSIEEAFQKARRDFDRLDYLVNCAGVHIMTPASTELAVSEFDLQNRINCRGAWLCAREGLKVMKEQSLDAEAYPEPVIPMFRDQRGSIVHISSVCGNTALPLTAAYSAAKAGVLALTKCDALDYASNNVRVNAVVPGIINTPMVRQTPELLKFHEDIVAKKHTPLGRMAEPEEVADVIVFLSGNRASLVTGVSWEVDGGFMNGRLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPC3</accession>
    <name>A0A6A6NPC3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_388262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPC3"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF3">
        <property type="entry name" value="F-BOX PROTEIN POF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="84"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="655" mass="72751" checksum="DFEA2849BEA8395D" modified="2020-06-17" version="1">MPEKINSLTDLPLDVLLLITPYLDAKSFLRLTSTCKAFRQQTILFDANYWSNATRSTFRVPNQPVVEHDGARWQHLFRRLLTQTRAYTWGSNAHGCLDHSQPSPEESRHYIGRRARASHPSPMQSTGDLGIIADLQCGGWSTTLLTSNGTLHTVGELDGGRRPRNIRGNLRELTYPIPFSPTSDAYNPYCRIKQFSSGRSHVLGVADSGSIWSWSSASKPGIHIKFMSHELYEGSQYSPTRPHGSVIKVVAGWTKSSVLIKGVGIVLWEIVHREGDDQNESSADTFMIGITALIPKTWYYRPVGSAREPSEDSRLVGQTIGQVRNYILLENFVVLVTDLGRVFAAKIVPESHGSFNTDLMVELTELQGNPDKDNEPCVKDVQGSFRSFAIFKSTGAVLVASQDYLHEQWNSVFDTANATQTSGTDSAIGRLRPHVKLIPALQNSGVIALAFGDYHFHALHRDGSITSYGTEPQACGALGLSGEGDPEGRIRGIRYTGPGRDGTLVRHAYTHGRHIWFEPEKKQWIRFMTSGGVNPEEAQVRMQMSMVDPWVQGEVSEWFEQQGTGWDKEGDIGKGVDDEGMGSYFALSVAAGGWHSGALVLVNEALADRVRERYVWAGDSFPRLSLSNGREMPGQVPFSEWKYGRPEFIIESDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPE7</accession>
    <name>A0A6A6NPE7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPE7"/>
    <dbReference type="OrthoDB" id="4161589at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="64047" checksum="E99E7418FF0B8B77" modified="2020-06-17" version="1">MADDTTNDGTKTTGSAFTAMNRSSQPAHSENAASSSTRYQPIASAPEAPASTPPDDLTPQQPAAKRRRTGGGSGNGSGSGPANSSSSSQHRWVANLTPEQLARKRANDREAQRAIRERTRNTIETLSARIRELETQNPYRELQRVMQERDSALTQNVNIKKRLANAMALLQPLLSGERGGVEAAVAGKGSERGAQGLDELAAAAVQSPLAGQHLQSHAPAQEVSGDNGQQFRPIRPLQKSQIDSRAPHSGSPEDEASSAPSRNANSIGATSPREERLGVEFLLQRRGSGDNAYTSDDNADSRAGSVPQGGLGDPSYRLGLPPTAHKALPFALPPTCALDQVVLDFIMEAKRGIVGGAPISSIIGPSNPDLRCLLRPESQPQSPESLTSVAAAAAAAAAAQQGGGKGKDPGSSLNRWTRVFTGIGDALPVLDGLPERVALIFVAFMFLRWIIDPTSDKYDRLTDWVSPRPSQLLSGHPAWMDFIPWPRLRDRMVQSTPHISFDDFFVPFFSSLKVEWAQQAQDVLLPTLAPRADAEDDGAAGPGPSSLTSSHVSVPEEQWVINPAFETQLRKLENWSLGPEFERAFPDLADTVKLRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU6</accession>
    <name>A0A6A6NPU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_128909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="11289" checksum="C78516649301B998" modified="2020-06-17" version="1">MLDYSVFFLFAGFAVLGLTLSLCMPFCLRGSVWFSCLFCAVLCGFVCQADCMAWSIVIVSYFCLSGQVFLLFTFAYGWYIVCLSYGRRRTKLNDIRISM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPW9</accession>
    <name>A0A6A6NPW9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPW9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="261" mass="27823" checksum="F78E2FC6DD247D5B" modified="2020-06-17" version="1">MIHSKPYLELHPSHSHAGSLPRSGRGSELPSLTAGFWLPSPSSTTCSRTGNSLAASATGLVSELFPFPSPSRDRNLFLHTRYPIPAMTETPHTTPIPTPAFPPADNEEEPGSKGIAVTTTVVAEKEDSGDADVGARVVARVGARVSARVGKSDVENTSVEIVRASPMSGFCSQPSFRARTTLAGGEVSSLGLASMKDDLWSLTIRHDLCLAGAIQTVRALRIVIEEAVHAIRVLERSICFEKSVDNGRPDWLARSTARSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ71</accession>
    <name>A0A6A6NQ71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Tim17/Tim22/Tim23/Pmp24 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_355238</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ71"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2453839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="16445" checksum="0A2016FFD8201BB4" modified="2020-06-17" version="1">MDHSRDPCPWVALSDFGGAFCMGAIGGAVWHGVKGFRNSPYGERRIGAITAIKARAPVLGGNFGVWGGLFMTFDCAVKGIRKKEDPWNAIIAGFFTGGSLAIRGGARAMRNSAIGCGILLAVIEGVGIGFQRMMAEQNTRLEPPPLPPQQQKMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ89</accession>
    <name>A0A6A6NQ89_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_367006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ89"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="278" mass="31917" checksum="C75EE817217032B6" modified="2020-06-17" version="1">MALKDAHKPPPLDEYDDDERVLHSASPLMYRTTHDLEQRGYATLENMERPKDDQKRALEPSSLLKNARQPIDGQCPASSLEYTTTHELERRSYAILESKNRSKPRLRVVAEKCFKAKKWPCYGDELDFQATSSKSLSELPEMPIANSPNRLHASWPQYESETRADLRHAPWNQQELMQELMQELMQEEDNTFGDDAVRPSQRCGPFSLTAVPRDDARLKSRPDSDIEQEEGVGLSGVDLNDYPIIYDTSETNFLKAFKKLFVDVPEKEKPGKEDTEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQE4</accession>
    <name>A0A6A6NQE4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQE4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="88" mass="9844" checksum="53D9A418E3CBE795" modified="2020-06-17" version="1">MRLRSADRPSSFRRGLAPRRKYRTCALRPAPLPQSHVISTSPSTARAILRQPNVPDSFARLATRSGLSFRTRTSRKERPPGARDVAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQJ6</accession>
    <name>A0A6A6NQJ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_355086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQJ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="135" mass="14298" checksum="D5CB99221BC4CCFC" modified="2020-06-17" version="1">MRRKGEARPEVALPDQAPQGSLGREAGVGRGALRPRHAHERRQARDRNRVRAVVAGAERGPRRRRRSAPSDDLVDGAAGLVVVVVPAIVGPGDKRVAVQLIVAVVVAAVAVVVTAVIAVVIVVTLLLLMLRLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQQ4</accession>
    <name>A0A6A6NQQ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_257695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQQ4"/>
    <dbReference type="OrthoDB" id="3911301at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="7276" checksum="98A65C74755184E7" modified="2020-06-17" version="1" fragment="single">MFSCVNYERGCRGRSNTINGRCDSCVALGLSTRQSPAASSSASSLSSTPTAYSAMTSSFASLSQLQRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR44</accession>
    <name>A0A6A6NR44_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beach-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_354308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01201">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1540.10:FF:000002">
        <property type="entry name" value="WD repeat and FYVE domain containing 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056252">
        <property type="entry name" value="Alfy-like_Arm-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051944">
        <property type="entry name" value="BEACH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108:SF4">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23295">
        <property type="entry name" value="Arm_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="6">
        <location>
            <begin position="1840"/>
            <end position="1974"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="5">
        <location>
            <begin position="2013"/>
            <end position="2308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2439"/>
            <end position="2480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="963"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1283"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1315"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1731"/>
            <end position="1828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="963"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1283"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1731"/>
            <end position="1764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1780"/>
            <end position="1809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1811"/>
            <end position="1828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2647" mass="296824" checksum="8E42786CBA2D2E83" modified="2020-06-17" version="1">MEPPSQRHRTSSAAHSRPITATPIYTDIRGLLKSLTESLPPPSARPSLGTLQVQCDDLRRLRQLLIDTDDQGQAGDAFRHARGFTALLDALRSVSGFYEPSRLSRDERTEFFELFRAVLQVLSEALNEHSGNKRYFAKRVEGGGWRALEQAIASTGICGTVVDGEVDDQTDLGYEQLFGLLFAFALGEEMLSPMFRDIGKNLVAPKAKEDVKRGENRDADLVDGQQPEVEIVGSGAAVDAKNNYVQRLRSHIRGFISGTEVVRNPDIFPILLNFWALLSADSKGTTQNRPAMSTAPLIALEEIVASSTHNKAAIHCSGTLSTVLRYLLDERTAGVEQELLRSLANSLLPFGVNSLDDAYKIFRKASRSSDIAELLLSGMRTSRGPPFIQFDLSLNGYSSVELPTLGPHQFPPTSTGGYTMSAWIRVDSFDVNCHTTVFGAYDPSQTCFVLAYLEKDTRHFILQTSITSSKPSVRFRSTVFRPGIWYHVAVVHRRPKATSSSKASLFVNGEFAEQVKCPYPVVPQSPAAGENFPNGMTYGAKLSPVQAFLGTPQDLASRLGRNVVSSKWSLASFHLFEDALSDELVAVYQKLGPRYHGNFQDSLGSFQTYRASAELNLYNEALHPGKEEKSEIVAAIRGRAKDLLPESKLLMSISPTAVMDDDDRNNIDESQLVRSLSRNAARQLKQYTQAGGNAIVINAAVPSINAALTQPHGVAILTAEPIVVVPQSLDDCTWRIGGCAAVGLKLVELAQTKCDIVRAVEVLFESVEENWRNSEAMEKEKGFSVLAALLREKLGYGTVFSNIPGRPEPVSVEGSDREEMSLKLLKAILRFVGYDEKRPEESIIINPLAYRILLVDFDMWRKSPLTTQKLYYSQFVHFSRDSKHHHFNCRRLTRMRIARRLMDALRGESFTEDIFPDFLSAFRCLVKANPSSETFRGLALFITFALHDSRAFVTRTLRSKTSTLRLKSTSTPPTNTPLTSTPRSISPARDMGRSAELSRGELGVRILELYSEMLCDRISTVDIRKFAKTVTNKWLLYLLAENEPRVVILGAKILSRLLVVHGSSYVKKFADKTGGFTIMKQRLRNWWNLPAVWLICFATLFGIDVSQLNFGREFELYTLVESFLSGNATNIIYPEIVPVITAMLETGLKAVLSKAATRDSSPTPQSHKDLALKKHLRQRSLSLGADASSINSDQHTIERAADNAAILQTVIQFLADLHQRSPKFRDFATSSNYVQDLLWVLYPVVVTSDSVSAETELHSRGSTLSLEGQDVLIRPRAISNDQRASIVRTTTVEPPPSPSSQKNLPLRRGSSFILVSSDRPDPSPSSARLNPVMSPKKTSPTISLKIGHSLVEALLETVIGVYQDQIFNRKEFPGFGLFLKVPPGFQEHQAYFESYVLRHAMSSLSNSVQLDQKLLCEPRVLTNLSRYALYMAEAVFEGWFIDGAEALLDFVGTLLEYLQRPDIARIKSVRLCTQAIATIRTVFMRVTLLRLSELDDPSKSHQAAAFLDKMTYWQTVILGPENSEDFFLRLICYLLYTHLVSVESNVRLSAANFWRMMLVQKPAETSILLSHGATSKQKQLSQGFMKLMELDNEAFLDWIDDHRADLDDFFFGAMSKSWEDYVAEENKRTQETAKNRVARRREKLRHWQLGAANEDDVWNRHEISTTHWRANIYSSERLKYQRSTQDQQDNLTFTATTYETLNRVLLGPCELFGEENLSKWQLDETEGRNRMRLRILPDRRPPQTDYQPKRQASEGAKNRLKLDTSVKSISSKDAVGATPSGPQSNSEGNVFESNNRPRSTSQSSASGSLVNEDEFEIIDDPKEDEDGFEDKNRKVMRSLQHGDQVQHVCNVSRIVGLDACEGLLILGKDSLYLMDNYFQRSDGEIVGVWQAPSEERDPYLQMIAGRQTTTARKPQVNVGEQTSRNWRWAEVISISKRRFLFRDVAIETFFTDGRSYLLTAISPSARDELYTRLIARAPQVTNPSSSLQPEDMWRLESLRNPDDAPQTLGSKFANVFNSTSSNPATRRWMKGEISNFHYLMLVNTMAGRTFNDLTQYPVFPWVLADYSSEELDLTDPRSFRDLSKPMGCQHASREAEFRERYHSFWEMADHNTPPFHYGTHYSSAMIVASYLIRLQPFVQSYLLLQGGNFDHADRMFYSIEKAWLSASRDNMTDVRELTPEFFYLPEFLVNMNGYNFGTRQGTGERIDNVILPPWAKGDPKIFIAKNREALESPYVSKNLHRWIDLVFGFKQRGEAAIEATNVFHHLSYHGAKDLDTIDDPIERLATIGIIHNFGQTPHQVFQRSHVQREETSLKYKRLDNSSESLTRLPFTLIETGERVSSMLFSANKNRLFCSAAFRLNIPPSYDRFMEWGFADNSVRFYATDSKKLLGVFEHLHQGQISCATFVDSKTLITAGTDCTIAAWTVVFGKVVDLQPKVNLFGHRTPVTTLATSRAFGAFLSASTDGKVFLWDLNRSEFVRELGTGGAHDDGEVPVQCAKINSVSGHVALCCGAHVRLYTLNGALLLDQNVCDEGLATSSASGGNGGNGGPAADVVGDDYVASCAFYEGIGNEWLERELLFTGHRRGVVKIWSVEADERGRWRLVLVKRLHSVDTNREDGANYAAAVSCILPTAQVLYTGDDEGRVVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRE7</accession>
    <name>A0A6A6NRE7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRE7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025579425" evidence="1">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="7291" checksum="5122029B649369A1" modified="2020-06-17" version="1">MNWHGLASLRLGYLCFLLVLVFCSCCSSVGGLIRRPSASVSYHIGPGFPTPPFQFFFFFVSAGLGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRL4</accession>
    <name>A0A6A6NRL4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADP-dependent mannitol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.138</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_354216</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.138" evidence="4"/>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRL4"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF14">
        <property type="entry name" value="DEHYDROGENASE ARBD, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00066645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00069279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="272" mass="29122" checksum="080C4E6B032A114D" modified="2020-06-17" version="1">MHFKRTLDSFSLEGHVGLVTGGARGLGLVMAQSLVVSGADVAIVDLNKEEAQYSADQLYDSFKQENPGADKLPKVTAHYADVSDPDSVNNVISEVLTAHSKIDNLVTSAGFTENFDAVSYPYDRMKKLWGVNVDGTYLFAVGVAKHLMERKAHGSIVFIGSMSGAIVNVPQPQAPYNGAKAAVRHLASSLAVEWAHAGIRVNCISPGYMLTALTKKILDDNPELSKKWTSLIPQGKMGRPEDLMGAVTFLCSDASGYVTGADLRIDGGYTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS33</accession>
    <name>A0A6A6NS33_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_373856</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS33"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000008">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="14"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="247" mass="26763" checksum="BC29190C8D37C923" modified="2020-06-17" version="1">MSSTEDEQKPERKTFIPLENNPEVFSHLVHKLGVSPSLGFYDVYSIDDASLLAFIPRPAHALLFICPSAVYHRSRATEPAEAPYAGRGPTEPVIWFKQTIGHACGLIGVLHAVANGAARRDYVAAGSVLDALLAAAVPLGVEERARLLHDSEALERAHAEAARLGDTAAPRPEEPNFHHYICFVKGDDGGLWELEGGWTGPIRRGELEEGEDVLSEKALDMSVRPFLKHAGEGNLDFSIVALAPSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSE8</accession>
    <name>A0A6A6NSE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_366105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSE8"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="104"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="350" mass="38833" checksum="E89C283E5F65C71F" modified="2020-06-17" version="1">MTIGNTQHYTDMDPEFAEPTLTHTNSKFLKSLGGRENLPIPETVSEQRAAFDNMLNMSNDINSDLNTGRKEEEVTITLRDGATVPARVYAPKEIPADGAPLVSHIHGGGFLSGNLDMDEPLCREFCDKLGCVVVNLTYRLAPEHPFPIGIKDAIEGVKWRWITKAAKNGPSYGANPKKATILGGRSAGGNFAGVIAHLARDEGWTPPLTGLFLSVPYLLDPSTLPEKYKDRDQSAKIDDSITINKKTIESILDAYKPDLTSPLFDVFNYPNGHKNLPPTYMHVCGLDPLRDEDLIFEEILRTECDVKTRLDVYPGLPHGFWQWTKLNATKKYFNDTVEGMKWLVEQSGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSF7</accession>
    <name>A0A6A6NSF7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_399863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSF7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="18649" checksum="7F09D65C5C9179AC" modified="2020-06-17" version="1">MSDLREGARSTTAKNAGRGVSPRGEKDQEGGWIGRPDAGKAVRAKAAAAAQASRGQPDQQRGRRWLPCLGTLPTRGQAGTGADPLEPSPVDDERPPRAGGEAGRGLTRPVATDAGDGAALERRRDERARCVSERRSGQAAGARGAWTRRSSGGPECPPRAQISTAQAKIGRLRGLRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSW5</accession>
    <name>A0A6A6NSW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSW5"/>
    <dbReference type="OrthoDB" id="5427664at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="20566" checksum="7E59A4D550DD87CE" modified="2020-06-17" version="1">MHITDTPDSIWWFWYAGEVLFGAMLMLKMIPATTAFLKWVGESIRHRVEDLLRSCGDRYEDLMDAMETEKPHRILLEASILFFFLIAGAMVWGLLTFLAFWSYGKIFPYPVQFLAHLVVFSWATFDILHIRTHNEDLVTGSELKMGFGQVLAIVMMAMVPFNVMDAFAAVKREMKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSZ3</accession>
    <name>A0A6A6NSZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSZ3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="65" mass="6823" checksum="6A3040BA36591AF8" modified="2020-06-17" version="1">MWRMELRESGCAPGSAERGRLVGVKDDGLPPSMAAGGRRQSGVSVVCDAGCLENGFIVLARFARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTR3</accession>
    <name>A0A6A6NTR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTR3"/>
    <dbReference type="OrthoDB" id="5423493at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="743" mass="80604" checksum="0C686667BE858A3D" modified="2020-06-17" version="1">MPRSDRTKVASGARNASRVAKSTVLAPAKTTRQTRPQQALERLGNKSDDDTGLPSRKRDKARPQPQPAIARGTAMTRTAVTRNTGKFIMTGALPAESSHSRRHARALNGSSDQSNQSDTNSDDSTGLVTKVKPSLRAQAVQRSAADLEMAHALAESRRDKIRLRNAERQRPEDVGANSDDSAGLVRSTQLQQLAREHDPAQKSNNFMMTGALPAGSGKRQPGARSKEAQSRPGNVVESAVLGSNQRNVATGHKSSSAGMITVGVPREEDEAIQETARQSSPRSSNKSPTLPGAAPHSEHMSSVLTLEIGSSPAREMAPPSVMKGTPAMESSLLALKNFRRRPRQPSILRMVQQTSDHGDIDDLDDFHPEDESTPLNVRNQRVSVSSGIISAYDGRQSSEPSSRKRKQDEVEEIQVPRSSPPPVYASANDVSSSHSSISLPEDVVPGTQEAEKVAGEPVILSETMAPPLSSVASSPTKPPAEKEPEVTHRHTTRRVRRRLNDAADGSDNDEHHTPAKLARRKKAAPTPATLSTNALHSLLPQRRQDGRSSRRRQDTAFEIPSDSSLDELQAPNTIMVDSQSEEESHYNARSRTRRRVTGLQSKPAQALGAPAKPTKGDSNKSGSAKKGKRKGGGTVASGKNKMSSPLAPRKDDTARHRRTYGRQSNSDKENENRNEESVFQSQSEPSDEEDTGVEEPVKAKGKNAAQVMSAELAAFAAKFKEVDNWEMEYESVDMYGQSSSPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU04</accession>
    <name>A0A6A6NU04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase F0</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2454987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU04"/>
    <dbReference type="OrthoDB" id="3342455at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013920">
        <property type="entry name" value="DUF1774_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992:SF1">
        <property type="entry name" value="DUF1774-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08611">
        <property type="entry name" value="DUF1774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="33711" checksum="B54F14EFFE1C0C35" modified="2020-06-17" version="1">MAGSGNVAERVQNGVHSVNPFRSREEHTRASIISLKILTAVTWLVAVIFTLYYTVERPHEGHYARRTIWGQNNRVRTPFSLDSIITSIFFIVLWILQVGYCWHLYSNNAAYVAAAANVGAHFVANNLLFFGFIHLWVRSHFWLAELLVVINLLNLSAAYLRHPATPRFIHVPVVSAPLAWNFVALFWCGAAMVHAHTLAARIVANIFIWAIFVFGVFFLAVFKDYTMGFSLSILCAALGVAQFLTKLVALQWIFAFVIMGVLFVLSCAVAVPGFLGIRDPFKRGEIVSEDRERAPLLQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV93</accession>
    <name>A0A6A6NV93_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7932 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_365605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV93"/>
    <dbReference type="OrthoDB" id="5319158at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057692">
        <property type="entry name" value="DUF7932"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25560">
        <property type="entry name" value="DUF7932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7932" evidence="2">
        <location>
            <begin position="162"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="927" mass="99557" checksum="8A1D95DD90D1DE40" modified="2020-06-17" version="1">MAAMVEGGKMASKVAKEFMVVTRRSTAMPNAGSGSNGANGGASANVFISVSEMDLDTLIGLSWDISGGKGGLSGTHGEPGDGGIGGKGGNGCSCGETREPQALQVLRAIGLDSTSAGVQPAPMDPVKSELLQVISYDVVDENEDKINEPGEHLLIRNIRVQNFEPIASEPLILPPNIPVGATVDVPGTLRTYIRNETVARAWNEPLCAKDHVSLIASFGRLNRAIPEFNMIRREIGIMYPLVLTSPKVLASVAKGDVVRFHWALKNNSTKAYGVAGGLRRGAATCLSDPQGVFNLSHATDGGREAIDELDFLEPGAEVPIDQDFTVSQYAGDYSYGDLRLDLQLSDPNPAVATKRVIMSYDIRMQVSGKYSHDPLSQFLLVVNSHTPLHAIHQTRRFIWNNLGLRVDTFNVSLVGSYTLPETQESVLRRYIGKSIIVFGNHFKFFDAGSRDPWSFLDPWEVSLLAKASTSFLFASTVNMQGLKGWGDMIAFPMYVGGHVEGHRAKTVKELVGSIHKEDQDVRVAASVAHTLSGQSASGTVKQMNKKLPLRRFATLKEGASSLAVIEGLPKTAQVFASVLGFSEGLQIPDYHAFMIVRSLPFYAQSRMFWNLAGKMGQVVPHHVLYGGLPGFQPLPNMNPTQFVIERKYCEAIGWAIESRIGTEVARFCSRSGWPHGIPGPILLDQLPLLSQFFKAAPQSAVITAAEGNEFLVQTLGTIYASALNIGFGRFVTQRVIRLGSRKAQLRPKILQAIRKALEACAPGHTATMLGAVEAAAKRTKDEIKGTKGKKTLGPLCAKRLALATRTAGADFVDLNTEINKISIKVKGPTASEMRTKHHGAIMGRSNDEGHAKAVLKERVVTDQVELDDIEAAPSPSTSPLVSVLEANAEAAQVPTLNTPELAAAAAAISTNVKATPVVAVAELAAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVF1</accession>
    <name>A0A6A6NVF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_60131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVF1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17223" checksum="2C0324FE3DEE23E2" modified="2020-06-17" version="1">MQVHTCVPYYENSTDLLARVCFSARTSPTANSNSVGAWTSPGNHPRVLVSALPTRAAANDLLRTHELTTLPPSRFQSGAVDRNAKPHPTPRLFLRSNTCRGPVRQPQTCRVAPCMRLDCERHALSERAVSCARDGRTSRVGGFWDSAFCAQLCREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVG5</accession>
    <name>A0A6A6NVG5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE affecting a late Golgi compartment protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_71050</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVG5"/>
    <dbReference type="OrthoDB" id="546861at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21444">
        <property type="entry name" value="SNARE_NTD_Tlg1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15851">
        <property type="entry name" value="SNARE_Syntaxin6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.90:FF:000012">
        <property type="entry name" value="SNARE domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000006">
        <property type="entry name" value="Syntaxin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015260">
        <property type="entry name" value="Syntaxin-6/10/61_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048036">
        <property type="entry name" value="Tlg1p-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09177">
        <property type="entry name" value="STX6_10_61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="13">
        <location>
            <begin position="163"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="28182" checksum="9063DB541DD92A78" modified="2020-06-17" version="1">MMASQVDEDPFLQVQADVLSQLNQAQPLLASYLRIRSSASSATTPELVEARTELETALQDLSTDLRDLVESVKAAEHDPYRYGLELDEVERRRRLVEDVGREVEGMREELLKTVHDAQAGGGKGKGTASGTGAAMNGDALPDPDSFDDEGHDDYAAFEEERQMELMQEQDEALDGVFRTVGNLRQQADDMGRELEDQAGMLEDVDNLADRVGGKLQTGLKKINWVIKKNEDTMSSCCIALLIFVLILLLILVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVS2</accession>
    <name>A0A6A6NVS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquitin-40S ribosomal protein S31 fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_423121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVS2"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031386">
        <property type="term" value="F:protein tag activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000008">
        <property type="entry name" value="Ubiquitin-40S ribosomal protein S27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="154" mass="17685" checksum="3B0FF9EC3A6ED1CE" modified="2020-06-17" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKVYTTPKKIKHKRKKTKLAVLKYYKVDADGKIERLRRECPNSECGAGVFMAAMQNRNYCGKCHMTYVFDESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVT9</accession>
    <name>A0A6A6NVT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">beta-glucosidase</fullName>
            <ecNumber evidence="4 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_372972</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 11"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVT9"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF29">
        <property type="entry name" value="BETA-GLUCOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025441317" description="beta-glucosidase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="14">
        <location>
            <begin position="803"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2455846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="883" mass="94589" checksum="9DED0E08BED76F22" modified="2020-06-17" version="1">MWLTQALATCVAVAARVQLAAAQASSSADAASTNSSGRPGAEFGQTSPPFYPSPWMDGSGTWGEAYEKAQDFVSQMTLLEKVNLTTGVGWMSEGCVGNVGSVPRLGLHSLCLEDGPLGIRSTDYNSAFPAGGTVGASWDRGVWYERGYQMGMEFRGKGIDIQLGPAIGPLGRMPEGGRNWEGFSPDPYLSGVAVAQTVKGIQDAGVIATTKHYIMNEQEHFRQAPEAVDYGYNISESLSSNIDDTTLHETYLWPFADAVRAGTGAIMCSYNQINNSYGCQNSHLMNYILKGELGFQGFVMSDWQAQHSGVGSALAGLDMSMPGDTLFNTGNTFWGTNLTLSVLNGTVPEWRLDDMATRIMAAYYFVGRDRTSIPANFNAWTLDTMGFEHPAAEADYGLVNQHVDVRANHARTIREHAARSTVLMKNSGVLPLSGEEKFTAVFGDNAGANPKGPNGCDDRGCDNGTLAMAWGSGTANFPYLVTPLTAIQNEVLGNGGIIQGMTDNFAYDEMTALASQSSVSIVFVSADSGEGFISVDGNEGDRKNLTLWQGGEEMIDTVTSQCNNTIVVIQSTGPVLLGSFNDNPNVTALLWMGLAGEQAGNSIADVLYGRVNPGGKLPFTFGAERSDWGTNVLYEPNNGLGAPQQQFTEGNFIDYRAFDRAGIDPTYEFGFGLSYTTFEYSDLTVTKHDVGPYAPTTGETAPAPVLGNDSDTDPADLVFPDDIRRLPLYIYPYLNSTDLEASSGEEEYGTADEDAYIPPGARDGGAQPRIPAGGAPGGNPLLYDVMFTVRATVSNTGPRVGEEVPQLYVSLGGDAPPRVLRGFDRLSIQPGRSATFVADLTRRDVSNWDTVSQNWVITDAPKTVFVGPSSRDLPLSQELDVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW16</accession>
    <name>A0A6A6NW16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW16"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="205" mass="23487" checksum="EE785199B332EED3" modified="2020-06-17" version="1">MEIERRTTKDPRSRALQRASIYKPGRIWRRRHSPSRPADGRPPWQQEAVNLLAAKHDMRRCDGLFRRPNGRACGRHARRRRSVVLPSLPQWLRLFLRRASSTFTSREKTVHGLHVPPDRHAAAPPSGVAPDSTPLLSTPLHSTSLHFTPQFHDLRSASPDENGTGERSSESPPRHVCMYVCTHVVERILHSAQRQRTARRPARPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW77</accession>
    <name>A0A6A6NW77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_61485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW77"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="429"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="723"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="751" mass="82384" checksum="0F16DCA8690306A6" modified="2020-06-17" version="1">MEFNAVQQFRPPSSTFIQNPNRHAAQIMYSYGNVPVQQQPTSSVQQPQRQPQPVGTWAVGQSSSAYQSLPRSHVGSPSEGGYPTSQPMEASNGPTSVPTTAMTSHPAFNIVSEPSMQQHDYPQRPVIDTSGVWNQKGCEDLEFATIDPEMSDFRQGFIETDEDTPIIDLRQYPGLEPDMPQHHGIGPRRSSESSFSMSSTGALPEVSTYEDHSAQEAVSYPDSDTWSALQDTPSMTMSPLASPRHTHRDLVRGGSRSRNSPVPHNNVRSSPYSLESNRYKRWSTGMAPGPRSYDQFNNRFSPYGARLNPHHSLPPYALNSMANFQQHTHNILYSQPHHMQPGNPTLFSSGEQPYQLEVPRPLPSQGLFRLLQSNADRHSGCSSHFADLSDPPDLYASLKEEPSDPPESDMNPSDPDLVPHEQDLRFAGDLYTPRWVRGHGNKREGWCGLCKPGRWLVLKNSAFWYDKSFTHGVSAATGAAFQGPQDTRRTEGNLDVWEGLCGSCGEWIALVSSKKKGTTWFRHAYKCHTHPKVKDGPKRRRETGHQIRVRAASTASTPTMYPVSETGAGNPGMAADSCCGSAGAGAGFSGTSSGGGAIAALPPSTSTIPEGEAVLSAADASEQQRQQQQQQQQQQSAASSSLGLSHEQGGPQAHGQLQGQPQIQIETEATGSQGPYAQGPLPPPQQHQHQPHPHGQEHRQQDQQDQSQDQQFQHPAPTAQMRQMHQAQQLHHSQQMQRGDFSGLSTFASMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWA0</accession>
    <name>A0A6A6NWA0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_289468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWA0"/>
    <dbReference type="OrthoDB" id="5361565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025679094" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="45"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="513" mass="55343" checksum="8AF0C10EF014C453" modified="2020-06-17" version="1">MAAFTRAVLALGALAQSVAAFNCSMPPVYVDIHKRIVHGTDIFQYGSFMGVGSPGQNQSLFPSLRNNETSVASVVFCDNSNLTDCRINTHGNYDSEASSTFENATDYVSLDHDEDGEGNHIREEFHLYTHFFEPDPASATVLEDFPVRVMTAGSRNPGVYGMGSSSTLMSHLVTQNRIASHTWSLYVGAGFDRAGGMINGSNTFGGVDVGRFEGTVYNYTMDLNHADPFPVRVKDVRLDMPSSDGARNVSLLDASRFPNLDDDAAFEGGSRTSFEARLSTDVFPFVFPDEVTRNFMQLTGAEASEAEDGSLRIPDPFNGTLAIELDDGFTVTLTAAQLRNVSDLAPIRAPRSADASSSSSSNSSSASGDAYAEPFYLGLAYLAHVYLMADYDAYAFHLAAAIVENRFVTPRTWCGKTTPVAYSVPAPGSFVANGMIGAVIGGVVGGLGLVALVITLFVVFKRRQYRKRERMVEEARAARTGAKMAQFVVDESEQGSPGPAKAPKASSGWLWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI8</accession>
    <name>A0A6A6NWI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_348820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWI8"/>
    <dbReference type="OrthoDB" id="4159838at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="722"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="949"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1087" mass="117517" checksum="1555E60A1A3337B1" modified="2020-06-17" version="1">MPSGSSGGDASKKKLRKRYGGASGLGAKASVPSSIAKELPQGLSTPRLPDGASFSSPAAFYIRKSFIPDANLPSPPKVGNPNGTILDQATWLGLRTKGSDATPTDVVLHATQLFKNFSDILRATGPEAKAQKQAAQKQAAQKSTSSKVALIQNASSQARSSQPTFSSQATEGGPASKLLGPAMQPPVSQATQKDAVSRLGPRSLFATCLRQVPTYLALAVESQALKEPEQQIDVVGQVYDDLETLGPVEGQGWVGLKRVVRSHAVLAVADAVRDRTIPMRSIKRLIETCIAETKSTQEAEQVLGAFCDSLKPGSGTSALDGKSLASVNPFGHCPKNGAQHRFANDLVKSFGKLCGGNSPVFRVMTRLLKERKMPLDWCFASDFMRKVSEAVSSVGGPDSAAASDFIQTVLRLCCGLHEEGEPHQEPSQLFMTTTTCPPSINLTVSGIATCLTTRALEDKLRHVSWGLDENESSTYESIIRPLETVGSDIIAAINSPSSATTFSAPGYLLHATMVLSSILTMRLFKCEFRPPLCSSLSIEVVVVGLSLLNRLHKNIPTDEERPTFQIPRQVCGIIRDIDMFLDGGRFNFEKLKHAVNVMAIVATGEPAVRPQSDENVDYFTEGPHSNETVRDFMAHLARASAEAFAKTEYARRDGIRTKSPTKTTVPAQLFAQEVCKRLPIQESTSPFMSREEEANIAVAEDENEGSEDELCRREVFKKDTMGGWAVTTPGRGAKPTYPALKKAPAVRSHTDFPSGPLSPVHSDSIYSHDENIAPTPCSEPSPVSPPSSGEISEQYPTPPTAATSPASDTPLVSQPFSRHEHRASLRARSQKLRAMSHGDNVTSRTQSVELISASLSRAGCPSSSDYERSSSEELSKQKQGKRRHPSLTDDDEYAPARKRSKQDVRTESKSHKRNRDDSEGGDSDMDISRKRSRYERFNSTRTLATPHQRSTYARAASAPPTSSPVSVEAHAVKTAFHSGYNSDGDDERDELSLDSINSPLVSSFFRKKKVNRAPARAFSRVSKTYRNSRAGSIARKAHAGIGKGRMAPRKSSAPTLSNMSSNVGESGSFIKMAREADDETSVDELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI9</accession>
    <name>A0A6A6NWI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plant basic secretory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_260133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWI9"/>
    <dbReference type="OrthoDB" id="891726at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007541">
        <property type="entry name" value="Uncharacterised_BSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321:SF12">
        <property type="entry name" value="PLANT BASIC SECRETORY PROTEIN (BSP) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04450">
        <property type="entry name" value="BSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="21787" checksum="5182FEA2C8A7CEA9" modified="2020-06-17" version="1" fragment="single">SSAAGNVSSATTRSRSFHHYYPIPQTRSVTLVLRPMPGVAYTTGISLDNDHKEIHLSTDYLCDLSPPHSPTRYRAEIVGVLQHELVHCYQFSASRCPGGLIEGVADWVRLEAGLAPPHWSKGRRKDGPWDAGYSRTAFFLEWVEGKFGVGSVARLNERLGDGKEYEEEGFWKGLFGKKVEELWEEYADEAWGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXH3</accession>
    <name>A0A6A6NXH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXH3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="21750" checksum="338CB330E01ECCBD" modified="2020-06-17" version="1">MFLDWDTAMWLPKTGIPPKLSELHIIDKPLSWDDEVLFDEDEARLLRGMVTPDVVNTMCDRYGNESELWPPNPDFLPPDEFASQTHRLLGLIRWLAARPSQNQTVKVLYLHFSHSKRGLRGLLAVVAEACARAHLLFKAKFEPLRPGPGHRFASTLTVYDPAWGIRAINRKPEYEDVEWESFLLADQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXV6</accession>
    <name>A0A6A6NXV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_346883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXV6"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="729" mass="80898" checksum="F968060F2297037C" modified="2020-06-17" version="1">MQSSNPTMQTSRMPTHSGLPQGMMHSRFATPQSPAGPSAMPSQKPTVMQMNNLQYGHPTLPSRAATPQNNNAMNTKTGDQGDQVRPDLHRPTPKVPDSVETAGGQNADEAKRLEDKAAREKKAREEFKRTFQENMEKRHEEEMNKGAGNQEDALAVWYNEQRNTLALKIKHESILLDENMKRSQELSDRRKELTTEMGALTKKLEDHAKKEKEARADAINIYLRMTKLQGDMNDLEKKADKNLKKLSAQASQLNLSPEAARVGTTSQNTILPATKKHSDVPPAAKDTSPSPSPRQVAMEPSTNPASEKNVDPTQTVPADDTKAEEDSHLKPAKATSQHTKETPSKDTLSRPTTSSSNDFMTTAAVLAVHKNTVSPATKSPGPWTPVNPYKAKPKIVEEPKLDTIGSSSEAEKTGLSEFQKDAARANVQTEGINRFNAWPRAIERQVKPLKVRSVKVSNIPSNFTIEKLYRHVWGGNLEGAQFKPGSSTAIVFFMQPEGCSQYVKDTANGVDVKNDNGTNTGGVLYVDKRNEPDPVSARLESYIKAMATRCVLVERIDKEWGDLGLKRAAGLDSRSLAFMRRGTNKFRELWVEFQFTWIADAMSFYCMVVRDEIDWSGVEVHFAADPCALVFFYPRRDVGTIMPTLQTRRLGYEEARQVSFVLEGRVLEGRVDCRGLGGYEKVLRHLLSSMVGVSILAAQCTFSTGPSSSKRVSKTESVHSRRSTRVLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY59</accession>
    <name>A0A6A6NY59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_40252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY59"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="269"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="445" mass="48770" checksum="902D1BDA7A897CFF" modified="2020-06-17" version="1">MAAEHGDRSHHGPRGPRDPRVPRAPQPLFAGDQFMAAFRQGQPSSTNTSEPQKKEDHLKPALFAPPQNVQTSRPPSAKPARDIGNLPPQPDVTATMFNGDSKAKLRSKAIETDTPDTSFRIAKKAVVRRADAPKPITSDATNQSSLGQTPAGMDRSTEPPSGYTNREVHGKENTPASYQAIEAQSTPRTVVQTTPARSNSQRAPETPATAPNVRPHAARDVPFSQPSAASAPRVPQPSASAERQRGQNASQIKSKNTRQDDPELRFVRMRNIAVAVKAEDIYQFFCSFRIARNGVTIHRENFRTAYVEFLSHEDAKEAKEALDRKPLCALKVTLDLVSKPPISVSDDHPTEVAPAGIRNHALAATRNINVGSQNSQGARGSIIGQERISVAEPTRARRPTLTFGLEASRYAAEVEDTQDHRLRVGLHDHFFHDTSSYTFARDARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYA1</accession>
    <name>A0A6A6NYA1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial distribution and morphology protein family 31/32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_379675</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MDM31/MDM32 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYA1"/>
    <dbReference type="OrthoDB" id="17678at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000001">
        <property type="term" value="P:mitochondrion inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012571">
        <property type="entry name" value="Mdm31/Mdm32"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31068">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31068:SF0">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08118">
        <property type="entry name" value="MDM31_MDM32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="124"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="734" mass="81726" checksum="F1AEBD40F1D1972D" modified="2020-06-17" version="1">MSRHVGRSGVGRLLWRSLADLRAAKPSGHAAFLRFSSSANGSTAPQPALLRGGPQYGLRISSSNYSTFRFASVSGFRHHPGTHLSIARCVSFAAIRSPPRISSVSVRPTQLPIRNLTQLAISGWKRSAHSTTRRRRAGGFVRNKSSASNGSKAQQQRLGPKSEQQKSGSRAKSGDKSTPPPPPPPSGGEQAAKNRPLLERLPHFPQHMHRPTKAELLEAATGFWSRVRVHFKWFSIKSMRPFNMDDISAFFSWILLGHVVWIIVGTTTFFSLAIFLVNTVFAQETLARWIGNYLTKSSGAKVVFESAIVPKWKDGVISFKRVFVSRRPGQGQSNVSKGSQTTAAAAAAALAGRAVDEDGAEEEDTNYTQFDLSIDNVNVTLSFTKWFNGKGLLKDVEVKGVRGVVDRSFVVSIPDVDPRTYKHEHNPGDFELDSFKMEDLLVTVYQPGNFRPFSASIYSCDLPQLRKQFLFYDFLSANNMSGSYDNSLFTIHPRQTHNYTGVQLSQGVDGEDQSQWKKQSRIRIDGLNIDHLNRGVQGPFSWIHEGNVDIVADIMFPADNDESIAKVVSEFYDRMEATVTSTATGENRRSSGHDQDAALPLGEKFKKSDQDDRCLVLDLRVHLNDVRAAVPLFTNDISYVNNALIRPIVAYINSKRTFIPVNCRVVKRVSEFDGSWTIYDSGLMDDLSREVYEAFARDVLDDHQVRRRRFKKVGIWTIQLAAQALFIGLAGNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYI7</accession>
    <name>A0A6A6NYI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_53797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYI7"/>
    <dbReference type="OrthoDB" id="3896584at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF72">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clr5" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="700"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="701"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="720"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="788" mass="84864" checksum="EE69A344361D3A7B" modified="2020-06-17" version="1">MTKDWDNVWQEIRRLYSIEDKSLKEVKEIMKRQYGFDASIRAYRLKIHSWGLKKGNGGGRRKERIRSPGGRHTPRAMLRQSVSAHSLIGQGVEGLSDDPAFDTVGQELTIDDEETVTRFKHLYDCVADTKVEEIKNFLDDPAYKPLVNYRIPWTNVRFGGDFLVHFAASQHNADVLFYILRHSTSQTINALSVSDGFHNQRAIHIAIYHKQPLNVENLITHGASVHPEGPCPPPLSSAVHHSASPSIVDLLLKAGANPNLPWPPEPGPSQTPRSAWQIAVKKRIKTFKDRRETCAKILRLLLQHGADIQLPGAGEDHAGSTFADFISPWHDVVFWYHNLTGDEHWILDQLIVQGAPIDAPFSSAMCASYNSNSPRRSGNARRGSRSHGHGSQQNRKVTFMHEVLFHTPGSGLGHSLVTFARPNFHPQLLHEVLSPCSSRACELQDDSTQQLLRVLMKSGFDPNARGADDYTPITRLLTFVDEVEVLPCLEVLLGGPSAASEASAGQPASGSTTTAATTAAAATNCGDGANPLLCDGQGRFPLQLAFESERFPEALRLTLAETLLAHARTTTPETSYLASYLPLTPWPSYHSLKYLTANGKLACSLETVFPTNAALAAFIQRAALSVATKHFLAHEVNLDPTSRYNVAILDALKMRRDAGLDDVPLPANFVVHLLEQLTNRGSNSSAAAAAAAASANPNPFGLGGHAHGQGQGLGMGGLGHHPHHHHHHSHHGHGTQAGQQGHPLVGMGGGMGGLTGLGGGMGGGMGAGLGGAMGGAWGASMIGGYSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ63</accession>
    <name>A0A6A6NZ63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_346634</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>precorrin-2 + NAD(+) = sirohydrochlorin + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="2"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ63"/>
    <dbReference type="OrthoDB" id="1721126at2759"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3280.10">
        <property type="entry name" value="Siroheme synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330:SF1">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="8">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="7">
        <location>
            <begin position="165"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="260" mass="28581" checksum="0E9B87D30D67A35F" modified="2020-06-17" version="1">MGGNKFPEVQGGGSLILAWQVRNKHVLVIGGGEVAAGRILNVLNADAHVTVICPSSGLNPEVRHRIQTGQVRTHINRSFQPADLDPPGVPDMVLCAIDDPATSSQVYKLCHERRIPANIADVPPECDFYFGSVHRDGPLQIMVSTNGNGPKLANIIRRFIAGRLPGNAGRAVERVGLLRRKLRRVAPGMEEGEKRMKWMSRVCESWSLDELCAMEEADMEGLVEFYKEGRVPKLAELRGESEGAEEDETVVGFDGAFGWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ77</accession>
    <name>A0A6A6NZ77_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ77"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="28170" checksum="96EC91B041FBB360" modified="2020-06-17" version="1">MRGKMPPRRAVEVPVYKSPADPSARAAFDDQLSDFPYNPWEYVPNRHVEPPKKTVSSDCPIPNARSEIVRRAYAADNTPYYALRIWRETGHGARLEEKNVHVFDVYDYVSRRQVEDFETRVFNEPQLGPDASASSGVAGRAGTASRADDADVGGMSIIAAAIADSEPDDESSEGEYASRVLGLGNNVESIEDDSYIGDMPYYRVVFEGDEDDREGHWVSEGELTKHLIERDEFKMLQNYWKDGIRGVSDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P014</accession>
    <name>A0A6A6P014_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">STE like transcription factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_371946</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the STE12 transcription factor family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P014"/>
    <dbReference type="OrthoDB" id="1095242at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990526">
        <property type="term" value="C:Ste12p-Dig1p-Dig2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990527">
        <property type="term" value="C:Tec1p-Ste12p-Dig1p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000243">
        <property type="entry name" value="Probable transcription factor steA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000390">
        <property type="entry name" value="Transcription factor stea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003120">
        <property type="entry name" value="Ste12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052127">
        <property type="entry name" value="STE12_transcription_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427:SF1">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02200">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00424">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="612"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="437"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="539"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="657"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="751" mass="81300" checksum="9FAE647BD66CF0DF" modified="2020-06-17" version="1">MPPQSRSVAPETFLLDQEAQNSLPPESIVALQQVDNLKYFLISAPVDWQHDQYIRRFLLPTGEYVSCVLWNNLFHISGTDIVRCLSFRFQAFGRPVKNSKKFEEGIFSDLRNLKSGTDASLEEPKSAFLDFLYKNNCIRTQKKQKVFYWYSVPHDRLFLDALERDLKREKMGQEATTVAVSEPALSFEFDSSQSLFEQLTKAQQTNSSSFNTNVQAQFSQSTSPVMRAMDSMPPPSIPQPMPPVSEEGLGQMSHFNQASMPPGMNNAVVKSRERGEYAPPMQYDRNGIPISQVHQRHSSMPAYMEYSPAPSFVSSHYEDYSTRGMSFEPLTPPQHSISLGTEPAYIANEDTGLYSAIPDLGVSNSFNPLMQLPPSSLGGGAGGAGGAGPGPQFSGMPRNFPPSNVYSVIEGSPTYKQRRRRSSLSTGVSAAVTATGATGAHAVHRPSDLRRSMSSSVMPVAEVEESSHESPPSHHGVGIGGAAAAAAASMNGGPYGGAPHMQQPKAEMVDLSRHGTPLATVEGSPVQQPMGALQLPQDDLASLTNGGDYSAEPQPQQQQQQQPPVTTTAAPLQHSALARTANAGSGAGGPGVFRRARSATMMELGPYPQKSHSCPIPTCGRLFKRLEHLKRHVRTHTQERPYVCPLCNKAFSRSDNLAQHRRTHEPRQDGEPVGNFSEEDLENLDNEDDQLGSLEEESPSDHEAAATAAFLNESALAAAAGSGVSAPAADFHAAMASMAPPPQPLIAAQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0C8</accession>
    <name>A0A6A6P0C8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitobiosyldiphosphodolichol beta-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.142</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_343970</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.142" evidence="3"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0C8"/>
    <dbReference type="OrthoDB" id="614844at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004578">
        <property type="term" value="F:chitobiosyldiphosphodolichol beta-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03816">
        <property type="entry name" value="GT33_ALG1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000162">
        <property type="entry name" value="Beta-1,4-mannosyltransferase (Alg1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026051">
        <property type="entry name" value="ALG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036">
        <property type="entry name" value="BETA1,4 MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036:SF0">
        <property type="entry name" value="CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="471" mass="52395" checksum="34A5BFBB5724250E" modified="2020-06-17" version="1">MQLNVEYVLGIALVLSTLFCLLLLALPSQYDPRLERSRRASSASLKGGHRKSKSKISVQVVVLGDIGRSPRMQYHALSIAKHGARVDIIGYKESDVHPEIQSDELINVVPIPPLPKRLRASNRLLFVFTAPFKILWQVLSLYYVLGYGTKPAKWMLVQNPPSIPTLALAWFVCFFRNTRLVIDWHNFGYSILALKLGPSHPLVRISARYEAIFSRFAFTHFAVTDAMARLMKEQYNVIALPLHDRPPMHFQPLTQEQRDSFLGRLPETAKFAEEVKTGGAKIVVSSTSWTADEDFSILLDALVAYSSEASLVASRLPRIIAIITGKGPQKEHYLSRIKSLTDQNKLSKAVIQTAWLSASDYALLLGAADLGVSLHTSSSGVDLPMKVVDMFGTGLPVVGWSDFEAWPELVQEGVNGRGFKSSDQLKQLLVDLLNEGAGQLDKLREGALRECGRRWDEEWDPVAGRVLGLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0F6</accession>
    <name>A0A6A6P0F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like 1-activating enzyme E1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_345312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0F6"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="8">
        <location>
            <begin position="48"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2457237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="637" mass="65147" checksum="87A01092A58AFC53" modified="2020-06-17" version="1">MNSSDAPAASSPAEANHRATVAHDMTSNTAQEQQLPGQHITADEIALYDRQIRLWGVKAQEQIRTANILLVSIKALASEVAKNLVLAGIGSLTIVDPEHVTEDDLGAQFFVTEDDVGKNRAEAAAPRIRKLNPRVAVHTHNIPLTTQPPSFFSSYQLVIACDLPFATLCAIDAAARLAGTPFYAGGAHGMYGFVFADLGAAHDFVIERDRPNVATRVGTREGPTRTIVHVASKKDGDKVKEVVTKRETYCALLLANAAPLPEAWRRNRRKLRTVTPLLTCLRALWEFEKVTTGPAGVENGLGMGAINPSAPTPTTATTTTSTAAAADPANPTTQQPAFHLSGRHPSPLSPPDLQLFTRLATTKHSELLLPAETLRSAFLRSFLQNLDAELAPVTAFLGGQLAQEAINVLGHREQPIQNLLCFDGEESVGMVVQLSPFVGEDGAGGAVAGSIDVGMDGMGAGGTGKDVGMGFGIGPGMGAGAGPVGMGTGIPGLAMDMAGGGPAAPMAGGMDVGMQNVGADMGGVDMHNMPVSGVGGMGMDMNMGAGMGVGTGIPGMAAGDPDMQTAVQNMDPTGVEGMNAGFGAGPMGAGAGAGVDALGLAPGMENAASAVGEVASATGMEGQSVETGAEVLPNPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0R1</accession>
    <name>A0A6A6P0R1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CDP-alcohol phosphatidyltransferase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_38913</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0R1"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043337">
        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000017">
        <property type="entry name" value="Phosphatidyl synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="45019" checksum="D646AC6E2856F75A" modified="2020-06-17" version="1">MIGLQLQSRLASGARQAAVVGRTGLVSPSPLLVAAFFSPRSFLSLSPSSSSSPLAASVRETVTRKPWTAPCNYCGRIGRTWSVSRTTPFLGSTATRIRSSSATGHATDNSLYDRYYASRGRLFSSETQKWSEKKPPKPPLRETTRVISERVKSRLSSLTPHENIYTLPNFLTFSRLLAAPVIGYLVLHSQDAAALALFAYAGATDLIDGWIARTWQLQTVVGSVVDPLADKALMAVLVTSLAAKGALPLWLAALVFGRDASLGLAAVYFRWASLAPPKTWARYWDFSLPSAEVHPTRVSKANTFLQLVLIGATMTLPLVAGGDGAIAGTATAYGVGAEEAHAVVAGLQYLVAGTTLWSGASYVWTKSAVRILGDDETLKKKQGIRGRAIIGLSFAACVALAGSLAVRDESQSEKGEEVEDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0U0</accession>
    <name>A0A6A6P0U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_25769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0U0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="166"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="27618" checksum="0B572BF78FFF2A1F" modified="2020-06-17" version="1">MSTSHSRKDLPPPSTTSYTWDRPPRRYYSPPRTNPPRYYSPPRARRPSHTTSLETTLELFVHTCFLFKAHARVIIRALPITLACIFCPPLAVYQLENQGCSLSFFLNVVLTACFVVPGIVHALTLYIVMGGFEASVGNNWAHLLTPAQLLEMELFFDERLLELEQEGGKGDKGRKESDHSSRGPSGRDENGGGGDGDSGYGDDPDNPGEGPRRGIARPDGTNRNGVSLPSLVFSSTPFYSVLTLPCAQLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0U5</accession>
    <name>A0A6A6P0U5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_344070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0U5"/>
    <dbReference type="OrthoDB" id="2937326at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="3">
        <location>
            <begin position="100"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="28496" checksum="ABA6EEEAE5C39E75" modified="2020-06-17" version="1">MWEPLTTGSRGGASECYERERKKDVRASVKSGKEKGVRASVKSGRRAAIICPALALSGRTLFSAGAEQHKATNECSLNLTKFPTRPNCPYSPAPPLPTMASELPTVPRVVFTILEPASLIAGFLAPLVAPAYFVDAQLPRTPLLAPPGHVPHALLPVEHLLALQLANLYLLLCLLGLLVLHTTREPAVVKAYLCALWLGDVGHVAVSAWAVGWQGLRAWRAWTAAIWGNVGVTVLLWLLRTAYLAGLFGGEKEEEEKKKKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1A1</accession>
    <name>A0A6A6P1A1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1A1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="66" mass="7408" checksum="6948CC5B0897621E" modified="2020-06-17" version="1">MHARRLHGHHLHDAARTYIHTHIHTCARSEAGANAAGPKGCLHPPRRRAEKAERYGVPTRYLPTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1A3</accession>
    <name>A0A6A6P1A3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_28137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1A3"/>
    <dbReference type="OrthoDB" id="4156902at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="157" mass="17509" checksum="555FF85D7E69B3EA" modified="2020-06-17" version="1">MRILTVFLQPHHHSMTHKTDIATRSFIIGLKSASCGKTTAEVSAITGVPGRTIQAIFARAIKRGFDPNIKPVVARDKYVIDAPRSGRPTKQMKQTKQTKQAKQTIDSTIKETQQRRLGYLSTDSIAYPQEDEFQEDNANSQVWIDEEDESGASSMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1T7</accession>
    <name>A0A6A6P1T7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1T7"/>
    <dbReference type="OrthoDB" id="3557758at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="390" mass="41499" checksum="F5C6E0A889B60716" modified="2020-06-17" version="1">MSLPGAPTGLVMQRRNTLLEETIVEETSSVRTLASSTRGSFESRRAGNSGWVAVQDGCRDDNGEVKEMPARLKGTTFGGHSVQTQPRLMQPLSPGQAPSGALQDVIGRKTSITGSLQAVRERLGEEENVGEEEERNDDDGEASPLAPRTHELRAMGPDEQPAIGPGGRRRGQYTIGGSFVDGDGNIVYVPRESVANGAASRVYGPEVNEAMPAAYWAGRFSAVHDRLYEAMCDGVPSVDAPSAERAGDVALARVKRSFAMLLSRCKTREAIESLRAFQHAYARINHMPSVVPSQIRLAPLMRRLENATSSSSSAPQQPQAQRPLPQPAQGMSATQQFQLQTDPFHGIGTGADGSGAPTGGAAPPGAAGQGQRSKTSFMDRLRARAGRKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2C4</accession>
    <name>A0A6A6P2C4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_343048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2C4"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="258"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="614" mass="68969" checksum="7FE3A8B1C56A4CE5" modified="2020-06-17" version="1">MSSTTSTPVPSLASSPSHQKIMSTYKFIFSGHEKNTSHSILTALRETYPDYHVTRTDFGSCDVIAYANAGHAEALLIDAINSEREYIPASPMSMLDFIDDPDSDYDSDDTAEKNSRHRDGDKLRDKVSFGLYAYKWNNMSFMVYTHKFAKRFEGPTKKLYVLAPRSMGMSSDGLYSVPTDQLLRVVGRWQATLHDEIYVFDDGMWAKSKELWRSVQGSSWADVILDPRTKDALVEDVHGFFTSRDLYEEFSVPWKRGVILHGLPGNGKTLSIKALMCTLYTSSMTAQDNEEDSFKHDDGEDNSSNGAKPRRHVPSLYVKSLQTCQGPQYAVRIIFSKARKMAPCMLIFEDLDSLVTEKVRSYFLNEVDGLESNNGILMVGSTNHLGALDPAIANRPSRFDRKYHFALPQKAERVAYAKYWRAKLERNGKVDFPEKVCDVVASWTSGFSFAYLKELFITALLTVARGGPCPGEEEDKEQPDGEGSDSSEKNFIVVGESGKITPIPEKVAVEDKSSEKDQKTVEDAAKQPGAKKESVVKMPEMVIPDELDDNVLLKVLRHQVRALLREMDNSKTASKGKKKKGEDYEDDEDNAEVQMMRQLLIRQAQAEAEACNDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2I2</accession>
    <name>A0A6A6P2I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_343448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2I2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="18239" checksum="045B09C389F705E0" modified="2020-06-17" version="1">MPRQVGTHDSTWPRRGRRSYFSLASLTSTSTSTSLRSASLGTSLSLAALAASAGAPLVAVASPLVAFAGAGAASSSSGSPSSGSPSSSSSTSASASGSSSSETASGSSSSETTSGAAASVFRFLALGGAGSSSTSSTSSSSSSSKEASDPSLSSYSSLSSSPSLGRAWSSSSSSASCFLFRVDIFLGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2W6</accession>
    <name>A0A6A6P2W6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2W6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="72" mass="7978" checksum="1A69B13D509FA6C7" modified="2020-06-17" version="1">MRFSLPAGPMTVCRRRRQGFSFVIKAGLEGAGLRVLFAASLLYLPQLLDLGFSYLQKTTPLLHFPPTKTLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P360</accession>
    <name>A0A6A6P360_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_371271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P360"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025488377" evidence="2">
        <location>
            <begin position="32"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="893"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="843"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="958" mass="102373" checksum="530FD99351E87735" modified="2020-06-17" version="1">MASRSRASPRAFQLLSLLLLALFALCAVARAAGPASPQEQSQGHGGEGLVPAAGDGPESGVAGTHSTAGSHNAACGRGGAGEVVACLLAPAAETDMAIARSLDISTVRGHLERRLSLLWLTAKRLFPSFVPGELELADWSRWQLPSLRATAWDMAKLAGEEHAKSEFWRDGSVRSLVRRKNGGNGDEAIETDPYTTDPGLLRKHSAFRSYTVTIPPGPSNPPHTAITYTYPSVRTFFTPHPHASKLPQTPTPIPLLVFVHGLGGSVAQFHPLLTSLTAIAPCLAIDLPGCGRSMFAPRDWAAYSTEALARLVGTAIAAHVGTGDDSSADHIDADNVHREKRRKAPQPIVLIGHSLGASIAALLASKSSPLAGDMFPPTSSVCVVGLVGICPRADPPGPDESVRLRRFLRALPGPLFDAFRWWDRRGGLQSKSVERFVGSKADREARKLQWRFNAQSKTSVWKKVARGAVPVYVYDDKGVRRPTQGLPGRDVWTGIEVPALLVAGEDDTVTGPGDVEKIKIYLGKGGGQTPSRLGGSEPLPAVAAPVDLSSKENLVRGTDVEDAVVKKIQADDVSSSGESEDVEATPPEEPAASKSRTTSGSDTLITDSPGRGAVLKITILPAPASHGLLYQPVQARTLSGLIQTFLERHVDARLALGWQLHHLSTEGKWDVKNLAKWRAVPPVSAPIAGLFRAMKTLREVDEVHAPKVFVKRWGWMAAEGRNGEGSRNNLDKSSGDAFAAAAAIAAPAPPPASSDTSKSPNASSVAALAAAAQDQQQPELPHSARDAVIAVIDISHEQPVYDPRGLEAGGVSYYKFPTVSKLPPSVEEVEEFVKLVDKLRGIEEEDETQESGDKGAAPMTELANDQGEAGTHESDKTVPRSAIPLPPRREGLIGVHCHYGFNRTGFFIVSYLVERLGYGLQEALDEFATMRPPGIRHEHFVDTLFVRYCVGLKRAPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P390</accession>
    <name>A0A6A6P390_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_19526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P390"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="25235" checksum="7C15A678015499A0" modified="2020-06-17" version="1">MDYLHSLLFPAIDVSRATTRNFSPLLFFYVLSPFALFLSTFVSTLHLSSSFRHEFSSFLLRQMLCCTPNMEGGRPFLALTYPFNALPSHTLSLSPAHILSAGFAPESFEIFLFALKDPRSCKFVFPDTQTGVSNHGEKGVFPHCFCQFFANPLISSLNVCDVTFAHTHVFLCRNLPRETSLREVSSLLLPRVFSFLLIPSLAYDEPTAILCTTAPDFLCSRRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3B5</accession>
    <name>A0A6A6P3B5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_204957</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3B5"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="91"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="200" mass="21448" checksum="3197575AA52F036E" modified="2020-06-17" version="1">MGAKSTAKSEAAAAKQAEQARKKAEKEALLREEEANIGSSKGAKGAKAKGAGLKSKGGLDLSGLDDPKLMAKMKGGPSGGAKKDAGPGKPGALSASNIDDALDALALTSAGGQSDKLDRHPERRFPAAYKAYEERRLEEMKDEKGLRRNQKIDQIRKEFDKHPDNPFNQANARFNSTKEEMEAIKSAERQKLEDRLGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3U0</accession>
    <name>A0A6A6P3U0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_208118</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3U0"/>
    <dbReference type="OrthoDB" id="3014581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF90">
        <property type="entry name" value="CENTROMERE DNA-BINDING PROTEIN COMPLEX CBF3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="616"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="701" mass="78231" checksum="33DC97E7FAEA2890" modified="2020-06-17" version="1">MPRNQTTPRSSRPRQEPVSCLLCRSKKLKCNRQNPCSNCASRGLPCSRSTPLALVGNSPGESDSSTAAILERLERLESEVSALNGGRTLLSGPQNDRRSPSLMPSTTASTTLSTAHSPFPTEEGVPQVDTHWLQGIATEGDSTVFNLSDKLVFKIQSSQHPYLSSSFIKDGSRQIDLPPLSDAVSIFRIYTEHIDYMQHVIHVPSVRGMIDEIYDRLSQDQPVDTSCVALLLGIFSHVAYFVSLQEEQEETFRAYRELLSSPTTFAKATLDTLDHCRRTGPSTLEVVQATIITGFLMFHIEGFTTRTRNLMTSAITIGRELGFHKLDAPSPGNSNNDPVGTEIRRRCWWHIASTDWLLGFMGGPWDMMYAVQPQHMVVNCPRHVTDEDLIYQGPQFSRPLTEPIIMSYFIQRIRLASVCRRAVDILSPGMINPGQVVYSKFAAVDSDIVKFFNELPSHFRVGPEGPSSSEDALLSPQVITQRYFLNFFAHSLRCKLHLPFLIRGSLHQQYQFSRDMSLDSAHATVRLVNQLDQSGPSIAKLDLRISGVIHQIFMATTVLVMDICLNKDQGLEDQRKADVMGALKILEDAVERSAMAKKFLDSLLATLRKHKVRLQNLGTTSTRSDERPPSAASALQHQKDPLDASNPAFEASNSFDPSLSQVPIEPGANIDEIWQTCMQMEPFVDSQNWDIILSDLDPRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P475</accession>
    <name>A0A6A6P475_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_340816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P475"/>
    <dbReference type="OrthoDB" id="2152248at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32846" checksum="D3DC67D7DEC0AD7E" modified="2020-06-17" version="1">MAPLAARCVLGWNERRRKGVDVGLVAVSFDMANHGSRLVDQKANLAWREGNERHAVDMWECYHSALPLIRDVLLPSLPSTLFPSPSTHRLTTHHALGVSLGGHAAWHLALHLAPMRSAAILIGSPDFSALMRQRAEKSRRPAWVAGRGRAWLGGSEDFPAALAADVARWDPAALVLGTGDDRDRDALGPDRVARRLREVLGPCLSGKRVLCLSGAADKLVPYERGKRFLDALKEAVGDEGGWWNREREEERVVFRDVVFEGVGHEVTAEMMGEALKFVWEGLEKEGVDEGAERRGSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P490</accession>
    <name>A0A6A6P490_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_283807</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P490"/>
    <dbReference type="OrthoDB" id="5212126at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF2">
        <property type="entry name" value="FLAVIN CARRIER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025660506" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="27"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="28"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="639"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="695"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="753" mass="81170" checksum="C1791F6F601B5279" modified="2020-06-17" version="1">MRRSLIPPPLAFLLTALLALLPSASAVRLIESKSLNPCQENSSFSATLFNVVFTPDNNTLTFNIVGVSEISGNVTADLEVFAYGYRAVKQTLDPCESADLAGLCPMNTGQINIESNIDIPEDVIRQVPNIVYTVPDIDGKVQIYINDTDTGESLACVEAELSNGQTVYQKAVGWVTAVIAGLGLVASAITSGLGHSNTAAHVAANAMSLFGYFQAQAFIGLSAVELPPIVGSWTQNFQWSMGIIRVGFLQDMATWYQRATGGTPSGLLTSLATTSVQVQKRSVEAVHRLFLRAYDEVLAKRTNNEVTQAETSRSVVVRGIERVGFRAKIEPTNIFLTGYSFFVIFVLLVILGVVLFKFICEGLVKAGKMKGEKFQDFRNGWKTVLKGIMFRIVLIGFPQMVVLCFWELTVRDSSAEVVLAIFTIVTMVCILGWASSKVIRIAQRSITMHKNPAYILYSDPVSLNKWGFLYVQFKATAYYFIVPVLFHVMMKGMFIGLGQGSPTVQAIALVLLEAGLLIGVSILRPYMDKKTNGFNIAIAAVNFLSSIFLLVFSNIFNQPGIVTGVMGVIFFIFNAAFALVLLIMVLVASGYAVFSKNPDTRYQPMRDDRGSFIKSQTQLTTELDALGATARGDKAAAAGAFAPASNNKPGSRFDDDDDDSFSSASADRTKEAGGLAAAAAGPYGPGSENPYYGYNPEAAAARSPSRGSNGGYSGYGGSGGGVADRSGSLRSERGQFRAQNNASPWNRGVGYEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P496</accession>
    <name>A0A6A6P496_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_212318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P496"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="183" mass="20218" checksum="C7C45C3FA4FF0AAC" modified="2020-06-17" version="1">MTDSTTSYVRSEDVCDIEAERQKKRPCTRSESYSFLASSDSQPNCESSNSQPQPSCTSPAPSYPKETEEDIGDLVNEDSSVVWSCDSPWMPADMDVRSTNAIWATENVFAFCHDRASLDISRDTKGPENTISMAQGPGVASLVGDFNLSGNESNVIPHTDFLIEDATVDNDQVCFGMVRHYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4B4</accession>
    <name>A0A6A6P4B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_384812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4066896at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031991">
        <property type="term" value="P:regulation of actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057454">
        <property type="entry name" value="Bud3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF21">
        <property type="entry name" value="GUANYL NUCLEOTIDE EXCHANGE FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25351">
        <property type="entry name" value="PH_BUD3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="251"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="824"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1135"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1459"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1544"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1609"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="857"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1149"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1175"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1267"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1287"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1496"/>
            <end position="1508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1639" mass="177560" checksum="3967FF4098527F8A" modified="2020-06-17" version="1">MVLISPPPPSLASSNLLLFYTTDSLLSATPLLIFYGPSATATFTATNSRIQTHVLSPAGLTSYPRLTVAPGSPLYAAVERLPREHQADEVCRGLAFSLFKFFAELPEHVRVAWERQLGSYAGRMPNAPAPFSDAHAAILAGRMQRVENVDEVVADVRSALAAQSLAWLDVDVVLPPGVMREVDRSRSSAGSDDLGDDPERAALRERYGEYASVARLFGEATFIPTSRLKRAPSKPTQLNRGSIFGRKHKEDVRLQMNELVDTEESYVAKLEDLLRKVADDFRQKAKRKSAQSSSPGEEALKELFPHSLDQILEVNGGFLEALKNTVDETVDEAIADIEKSFDDPDAARYDLQHSSQQPDVTGSVALGKCLLEWFPRFAECYADYIHRHSNFSHWLKMFTKETTSSFAKRVHETGEQRLMSMLIEPVQRLPRYNLYIDSIVRSLPTRHPAIKPLLRARDVISDICSRDSDAMSKSSEVDRFRALVSGWPAHFRPVGRFISAVDVMELQPPYRLDAEDQGRRSGILLLFADHVVYLRKQSANAKNARALVAELDNPKLSAQLAIREQIRPRTPGTDLEFYQDMELSGVNVSEIDSGEVIQLIESKSSSGKRPSSRDGKSTSGIRKARVFHFTGTYEGRAARWIEEFTKARVEGRFSEQERESHKWEVRSVSGDLSLFSAIWEDYTDEDGCGTPPAGRGPPAPFRIAVDPAQEDGGDFQAGQDGLEAVACLTSIGEGFFRLEINGLDGYSTRDHVTAGEFMPVLTKRLSNLLQMRCQIRYPTMTATLLQRNYQILVSLHVRLEGSETLEAKADKIARSQSPAKIFSNLFGGSSKDSATPKRLHGRSAASSLEDIPRMAPPTSNSRPQSRSGDPQRSESQLKGTIGKNAGHEASNHLGKLEETLSSYVLALHARKGNVVGRTLLARSSANELSVNELYNSLLEDPRNHQLAAQVTVDVLFAAFEKFLNIAWRDNMGLVLTPELMTDIQAKSDSLFQPDFEEYFHTIALGDMSPQNQRALRAIVKLLADLLDGTGNDGDRGIMTASFAEMLAPATNPHNFISVLDRFVEDIEALFGEPGTGSSAQGSMTSESTHAAHASKTGSVGSNNSSFRKRFGIPGLNRENSKSDFESKVGAVWRTLSKGGHGHGHRSGGDTSQPASISKAASHSTSAQPPSLSRSKSTDVDARLSPKRPVSRDRPTVLGTFPWEDQPSPATPSLGRPPSSGRTNSHLGTIGEANEAPRPPPRKKRRSSLSDLKSLQQFASASGTPEWATPTATPGASPAKSNLGGTPARQSSAEPRTPTSSNSPLKRPTNIPSPVRGYSPVRDSLKENTPLSPTKLQPHEGSPGKPRGGSIDRTGGYHSPGKRWPDSVSAIPTLKPTPGTGGGLSERPTAGNSTKLPQPPSFEKGGAGDKTPARSSSSSPTKKLRMQSPQKLRERLQNEQKAINNAHAALQAELSKIGEEISSAAPNSGAGTPSGGSRRVRPPLASGTGSLSRGMTAAAAASGASPGDHAALAARVTALESKLPALASDLSARNTAIAADVASSLQVSESRARRLDELYREANAENEALYARFNEELVKVARGAVKGGGGGGAGGGAGTADVQELLGRRWKEMEEEVGRLKRENGRLKREVVGLRAQLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Q0</accession>
    <name>A0A6A6P4Q0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_211489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Q0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025340934" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10175" checksum="C10C9DBFD641B22C" modified="2020-06-17" version="1">MPRANPFMVFSVCLFCSVGNLYYAVDRATTPIAKMGMRDRVTQPPPAKSSGIHHCSTNFSYSLGLPFSTKISSSAVPISIPSYVSLVRLPLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4R4</accession>
    <name>A0A6A6P4R4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4R4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="18794" checksum="DBA3605564AA55CE" modified="2020-06-17" version="1">MIRPVGKKVVRDSKHGHRRPPRSSKTSGWVATRAANASGAVAAEGRSGCRSTTKGQAGERVREQARRRRARPKQRPAGVERSRDTGLQGRRSWDEAPTKASGRTSEREGVNSAAPGVRPVGRRGPSGVGRFQPVAAAIAPARQKKKARWNWRQPRVAPGLCACQTTPRRVGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5F6</accession>
    <name>A0A6A6P5F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CTLH/CRA C-terminal to lish motif domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_199495</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5F6"/>
    <dbReference type="OrthoDB" id="2415936at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="3">
        <location>
            <begin position="64"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="29067" checksum="7A78707A2DA373A8" modified="2020-06-17" version="1">MSSSTVSTTTPTRHQFDRRVEEVKPSKTDMNFLVMDYLISEGYPVAASKFAAEANIKPGPAAESIEERVEIKQAICSGDIQTAIEMINELNPEILDRDHALHFSLLRLHLIELIRTSLAMPPNKTDITPALQFATEHLAPRASTNSEFLEDLERTMALLIFSPTSLTPELKALLDPTLRQQVANHVMEAILRSHGQKSEARIKDLVRLRAWLESKARDAKKDIPDSMPLGLDGEFGEAEGNGAHQGEDGVSANGNNQDGDAMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Q2</accession>
    <name>A0A6A6P5Q2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial outer membrane translocase complex, subunit Tom20 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_282637</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Tom20 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Q2"/>
    <dbReference type="OrthoDB" id="2154253at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016031">
        <property type="term" value="P:tRNA import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.10">
        <property type="entry name" value="Mitochondrial outer membrane translocase complex, subunit Tom20 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002056">
        <property type="entry name" value="MAS20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023392">
        <property type="entry name" value="Tom20_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12430">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12430:SF0">
        <property type="entry name" value="TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02064">
        <property type="entry name" value="MAS20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037707">
        <property type="entry name" value="MAS20_rcpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00351">
        <property type="entry name" value="OM20RECEPTOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47157">
        <property type="entry name" value="Mitochondrial import receptor subunit Tom20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2459137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="19296" checksum="678ADE6F1EC3402E" modified="2020-06-17" version="1">MASTEPALRTSTIVAACVGTALTGVVAYALYFDYRRRSDPEFRRALKKASKRQEKAAKEAAEAEEKEMRTRIKAAIATATAETDPIIRSGSQDEHEAFFMQEVAKGEALCQDGSDPVDAALSLFKALKVYPSPSDLINIYDRTVTKPVLDVLAQMIAADPSIKVTARRPGSDDGANVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P605</accession>
    <name>A0A6A6P605_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_337915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P605"/>
    <dbReference type="OrthoDB" id="5421247at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22243" checksum="D4CB75E2A47A7847" modified="2020-06-17" version="1">MPSLNELETAAADVLNILKGIPEFSNARVAVIGGLALWKYIPTGRTTEDVDFIINMDSAPHGIKQKLLTLPNSPFVQLAQVFFYKIPGGPNVQLDITPEWQSPYMPAAAVKLKDIAANAIPYISPTDLIIFKINSCGLRSQGVKKRTDAVDAETLLARETLHSPLTLTSTQQAIVAPCIVDVVTHGRQSEQWWRQRLGLPTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6C3</accession>
    <name>A0A6A6P6C3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_408775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6C3"/>
    <dbReference type="OrthoDB" id="3259529at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="269" mass="29922" checksum="AD524FA53909D670" modified="2020-06-17" version="1">MGHQCLRQIRPPTGTSPRREIRVEQQTVSEMVAPVVRLVQETLARGGVAACVVGELALNYYNVPRVVHDVEFCVGTDELEKAASLLQERDGVSPAALCDFDLYTAHLQGFPRFRCDLRDEPPAHVVLFSAASMRLDPIKERVVPRELHSPAAQYSREILESLAAPDLQSVDFPRLAPFFAGLCRRWLDASDGVARIAAEQLVDGMDLDEAWCRRNLLPSESSACVQFALELVSDKKSRVDHFVDHAITCFVGDKDEVEKLRKIPGADET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6M5</accession>
    <name>A0A6A6P6M5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calcofluor white hypersensitive protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_338475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6M5"/>
    <dbReference type="OrthoDB" id="68581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000031">
        <property type="entry name" value="Calcofluor white hypersensitive protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="658"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="284"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="3">
        <location>
            <begin position="458"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="5">
        <location>
            <begin position="691"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="956" mass="106353" checksum="6E575CA763F4DDA6" modified="2020-06-17" version="1">MAPKYKDGDVVASFSGKWISWTHTVVAYMAFLGALIVGIALHYRKIVQNEHYGYPQEWFPSVSATIGDRYPERSVFQVFIAITSGPRFALVAMWYMMTRRTTTHKNSSLPKFITGVGLFRTLTCGGWTYVTSTDDHDWHDIFMISYLVATLPWTLGCLALSPPNPQAIKYRRAFAGAFFGTLVPLIYFFIQHKVHRVPGAYTIYAFFEWSLVLLDVAFDAVTVMDFESFEVVIRDVKGVSRGTGKTHADFVLEQEKNREVAEVFNQSFSWPMALDTVAGVYNGFIFWSTLTSLGVTIWYFPLWYMGISGYEALVMSTISPFFLGIAPFRRFIIKNLRATHLITLVGLLSYLIKSPVYRLFAVSFGVFTGCLAWTATFYAERSQPHRLEARITSFSLGLLASSIAKFAFQTNNPIWPIMHGPNGGWNKLGIFLGVLAILRSTRSTASNGADLLAPGSRKGSPVAAAFGISGLLFALHSLLSDSSTMILWVWEGYPVRGPLSVPHGTYTFVAMGAGIVLGLFAPALARSWTMFGIGAVGAAVLTCFHNWFGYYGALALTVYLMAACPVIISSGIRHSPGLTFGLGFFFYNVLVLAHVWVVAYAFVPGGPLMREHTDWVMTATMLCIGAGIFSAQTSAASPANQKARVKPANPNARRQRSYYLYALLVLELLGASVAYLRFPSYNYKPHHGDSKAITAGIWTIHFSLDNDMWSSERRMRDVLAELELDVVGLLESDLQRIIMGNRDTTQYLAEELGMYVDYGPGPNKHTWGAALLSKFPIVNSTHHLLPSPVGELAPAIHATLDAYGALVDVFVFHSGQDEDPEDRRLQTEYLSRLMAASPRPAILLSYLVTKPKQGNYNTYVGAASGMRDIDPSDWDRWCEYILYKGLRRTGYARVSRDSITDTEIQVGKFVVGQPEGTDDLIDEADVPADLRFPDLFKGNGVRGHRYHVFNQPRYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6V4</accession>
    <name>A0A6A6P6V4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UAA transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_407334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6V4"/>
    <dbReference type="OrthoDB" id="999962at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005462">
        <property type="term" value="F:UDP-N-acetylglucosamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005464">
        <property type="term" value="F:UDP-xylose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF4">
        <property type="entry name" value="NUCLEOTIDE SUGAR TRANSPORTER SLC35B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="370" mass="39835" checksum="DA73EE8645DA3FB4" modified="2020-06-17" version="1">MIPGLLELGIVSLIFGGCCSNVFALEAIVKQEPDSGLLITFFQFLLTMLFALPSQLDPTRPPFFIQKSAVPFRKWAASASMFFAVNMLNNWAFAFQISVPVHIILRSFGSVTTMAAGWLRGKTYSRVQVASVVVLTVGVVVSAWADAVAKGKSMSTSSIDLTSASFEAGLLILLVAQLLSAYMGQYVQDIYAAHGRCWQQNLFYSHFLSVPLFAPLAGTLRGQYARLARSTPLLDYVAPPQVELVEPDAFSAGEGSAALALARRLLARTPTSLALLLANAATQLLCISGVNVLSAHSSAVTVTIVLNVRKLVSFLFSVWLFGNEMGGQMVVGAVLVFGAGALYGWETSVGIRRRRAEEEKGGRERGKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Y4</accession>
    <name>A0A6A6P6Y4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_281803</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Y4"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1-ATPase_alpha_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.150.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004039">
        <property type="entry name" value="ATP synthase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a_nt-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009884">
        <property type="entry name" value="PRK13343.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="15">
        <location>
            <begin position="71"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="13">
        <location>
            <begin position="194"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="424"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2459745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="554" mass="60142" checksum="781AD47ADDA1760C" modified="2020-06-17" version="1">MFRSALRQSTRTVGAISASGRIASTRTTPAIYNAAPKHVRTYASEGKAAPTEVSSILEQRIRGVQEEAGLAETGRVLSVGDGIARVHGMNNVQAEELVEFASGVKGMCMNLEAGQVGVVLFGSDREVKEGETVKRTGQIVDVPVGVEMLGRVVDALGNPVDGKGPIKTTERRRAQVKAPGILPRRSVNQPVQTGLKAIDAMVPIGRGQRELIIGDRQTGKTAVALDAMLNQRRWNDGNDESSKLYCVYVAVGQKRSTVAQLVKTLEENDAMKYCVIVAATASEAAPLQYIAPFTACSMGEWFRDNGKHAVIVYDDLTKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEKHGGGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGVRPAINVGLSVSRVGSAAQLKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDAATKQTLNRGERLTELLKQKQYSPMGVNEMVPLIFAGVNGFLDNVPVSKILQWESDFLAHLKTNESELLGQIDREGALSKDLEQKLRDVVESFTKSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P701</accession>
    <name>A0A6A6P701_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_338756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P701"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="9208" checksum="AC005586C9B9C08C" modified="2020-06-17" version="1" fragment="single">MMLRSTKFFWACSYVIIPTSASFRLSKIMLGGLHNNVNGHWHGSHVPPCGTPPNIGYPRSQLPKVTAFEEALSVSQTPQQQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P709</accession>
    <name>A0A6A6P709_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_282117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P709"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000135">
        <property type="entry name" value="Beta-galactosidase, putative, bgl35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.20">
        <property type="entry name" value="putative beta-Galactosidase from caulobacter crescentus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040719">
        <property type="entry name" value="DUF5597"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18120">
        <property type="entry name" value="DUF5597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 42 N-terminal" evidence="3">
        <location>
            <begin position="44"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5597" evidence="4">
        <location>
            <begin position="395"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="567" mass="63116" checksum="6CDF9F7FC23B4542" modified="2020-06-17" version="1">MAPSYHVPFLQETPHSKQLVVNGKPYLMLAAELQNSSLTSAEYMNTCWQKLKDTHINTILGCVTWEMIEPEEGRFDFAELDRVILDARRHEMHLVLLWFGSFKNGLSTYAPAWIKTDPKRFPRAKLRKAGGHLETGDVLSIFHPEASKADSKAFGTLMAHLKELDEAHSTILMVQVENETGLLGDSRDGCDAANRKFAELVPAELTTFLSSSWESLHADLKANLATFRVTADKRSSGSWEEVFGKSHHTDELFMAYHYAHYVERVASAGKSAYPLPLYTNVWMNYVGNNSDNNFPTVAGGGGKPGEYPSGGGTPTVLDIWQRFAPSLAFIAPDIYLNEYTSSCANYRHRNQPLFIPEQRRDEYGARRVWAAFGSFAALGTSPFGIDTLEPATNPFTKHYGLLDQVSEIVLDAQRRLGSSVGFYFDEMHANGRDPSPSKTVRFGEWEVTIQRCFVFGKPGTGAGMVVHLGGAKFLLIGWGFHVVAKNLSPSTSFTGILRFEEKMVANKDTGELKTARILNGDETRSGKFAMMPNRDPDYGGFPICVTIPARTMIAELEMYSLDEKDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7A2</accession>
    <name>A0A6A6P7A2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_336239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7A2"/>
    <dbReference type="OrthoDB" id="5589325at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025680017" evidence="3">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="33"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="23347" checksum="C494FBB40C4CC42D" modified="2020-06-17" version="1">MHFAQTLFFGASALATLVAAQSNVLFFTSVPTLFEAGEPATIEWEAPTDDPVTLTLREGDRGDLDTVFTITSDATGGSFTWTPPSDLEVAPDYALMITQGDEINFSGQFTISGGTPEESASASGSSASPSETASESASASASASASASAESGSASSGSMTSTGSMTSTGSMSVSTPSSTGSASMTSTETESATSTESETPTGTEAAESTGTPAPSDAAAGLPAPIALALGAAAAAMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7Z2</accession>
    <name>A0A6A6P7Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_361833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7Z2"/>
    <dbReference type="OrthoDB" id="3645052at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="284" mass="32688" checksum="35BCB6F1F5164283" modified="2020-06-17" version="1">MEPSNVVPSSNGKFAIWKSYALRGELGLYYRSPLFRLPRELRDRIYEFALGLDCNDSPASRVEIVYEGNSRRDFQGPVALFLVSKRVSEEARGTFYTKTTFSFADNVGPALLESFLFTIGPDNCRMIRKLSVNIAFPEILSFNSKQAIIRGEIAEALIHNGLMPVPTPKRDRDFGPLHTSLQTIARLCKLTRLTFVMSGLNLCQMGEDWRATPQEGHSVRQLRIWKKRMTWMESLLRQYVRVVPEGRAILVIRVCGFPDSEWHKLTNVERILESWGWKPTRQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P883</accession>
    <name>A0A6A6P883_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_186698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P883"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="19193" checksum="985E4C285E6591FF" modified="2020-06-17" version="1">MDIFLTIHAQSSIDAWWLHVKANIKQALCCHCIHDYVSGVCRLSWHQSIVAPRPHWSWQTSSCSSRPLLTLPSMGMTQQCWTHSGGANRANRTARRETRTPFPDFVSLVATGSAKQPRPFDLAYSSFSYFRPIKRSSFPETLFSATCLHPVAKPDGLVQEESQASPTLPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P892</accession>
    <name>A0A6A6P892_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cellobiose dehydrogenase-like cytochrome domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_186912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P892"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025436460" description="Cellobiose dehydrogenase-like cytochrome domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Cellobiose dehydrogenase-like cytochrome" evidence="2">
        <location>
            <begin position="35"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="210" mass="22406" checksum="640B35E8AB296045" modified="2020-06-17" version="1">MAGWSIIAMTIAMHFSAALPFLFAAGAYAQVSAEYTDEETGITFQRFSADAIGYSFGIAMPSDTSSTDFIGQVTGPSTGWSGVSLAGQMLNSLLIVTYDDADAIDSGFYMANTYGSPPEIEGDFSMTPIPSGTSVTADGFKYTFLCSDCIQSDGTTFQPDMDTVLIGWAYSQVEPVEGIFTKHSMQGQVPFDIASARSEDFEAWSSMVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P929</accession>
    <name>A0A6A6P929_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_335063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P929"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="86" mass="9383" checksum="48389EDF700B5485" modified="2020-06-17" version="1">MPLGGIENCGFVGLGICCCMWAGMPGWAWCCCPGWWCCCICCICCICCICCMCCGPIWGPPIPGCLLGRFATRLRNDWEALRSGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9H4</accession>
    <name>A0A6A6P9H4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleolar protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_408241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9H4"/>
    <dbReference type="OrthoDB" id="441771at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007276">
        <property type="entry name" value="Nop14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183">
        <property type="entry name" value="NOP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04147">
        <property type="entry name" value="Nop14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="304"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="735" mass="81662" checksum="E69C5D08E123B87D" modified="2020-06-17" version="1">MPPSQLKRLKASLREQGITGQQKSKKQKNNSKKGKGAGNGDERARRQAALAGIRESFNPFDVKMLSRPRKFEVTSRDSTTGKNGGVLGRPGASRSAGEEARRRTLLVEMQRRNKVGGIVDRRIGENDPTMTPEERMMQRFAREKQSRKGASLFDLEVGSDEEQLTHGGRTLAFGEDTKDLDDFDAGSLADSSGEESEVRLRKRDRRALDEEDEGNDAQELGEPERKKTKSEVMKEVIAKSKLHKYERQHAKEEDDDLRAELDKDLSEVLAALQGQPAKPARPETAQKASGTADTIPDGEAVIPDVEKSAVEREYDLRLRELAQDQRSKPTERTKTDEEKVKEHAEHLERLERKRLRRMRGEADESDEEGPVQEEDDIHQDSERDDAAEFGFTSSIPANPSFDVEDEDEFEIDEDLLASGSDLEPITDEEQSEEESGDSEAEDDDEFVRNIISADEKLKAQSASASVAFAYPCPRTHEELLSVLNDVPVESIPTVVQRIRALYHPQLATGNKEKLSDFAVTLVQHLPYLSDPSNSILLSVLESVTRHIHSLSRTYSLPIAEAFRAHLRSIRARAPDSEGSMTRGDLAVLTAITTIYPTSDYFHPVVTPASTLMARHLGLRRAPRSAADLAVGAVLLHLVHRAQKRARRYVPEAIRWLALSLQLGQDEGFRASFGSDDDGSGIVKVLEPYFGFAAALADLWADAPSFRDIFAPKITAALLPYTLRGARAAAREEGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA65</accession>
    <name>A0A6A6PA65_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_134071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA65"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="18647" checksum="2D48A5DBC81449C4" modified="2020-06-17" version="1">MWSDSRHRQPASQKTDGQPYFPTSPELRTVYISAHIFFRTQYQPGGASSSSSKKKKLRRPSRLRRATTPPPPGNPLHLQISRCPPWALRRPPGGSQTRLECSAHRVEDPGRVEFCWLPRRVWVMLLSAEWASHIIAFGRRGRRIRKGTERGGRRGGELREVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA86</accession>
    <name>A0A6A6PA86_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_333202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA86"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="65" mass="6888" checksum="8AE2437835BC55AC" modified="2020-06-17" version="1">MPGPGAHQPRGWPDVINACFVIRPSAYPPFIHNVPRQSNSPTSRPINHPSTPPSTGASESCVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAD3</accession>
    <name>A0A6A6PAD3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_413084</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Lipid hydrolase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAD3"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07229">
        <property type="entry name" value="Pat_TGL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="265"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="458"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="667"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="673"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="705"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="714" mass="77264" checksum="98176031D0D0B15D" modified="2020-06-17" version="1" fragment="single">MHPRDPHVLSFELSPGTAPFFLRNHDGIGAGAPPFPSTPPLPASIHCLHGHHALCVQSAVVNVMANKQQYRALVVLNSVYTILFDVLFFWQRRLISWWFRKSPRDVLLETLAEARVYEEWEAAAFQIDEVLGYDLWRQNPTSKYYDYRLIYERLQAILDAREDDDILSLVNLLRSGLVRNLGNITAPRLYNRAYAGTKLLIEDYVTQVALAVESVTNYPTSPTFGNSSNSLNYYDHGSGGASVLTNQAKLDVLHDTRQAFGRSALVLQGGAMFGLCHLGVVKALHLRGLLPRIIVGTATGALIAALVGVHTEDELLDFLTGEGIDLSAFWKPRGTAAGEKKGTTVLVYSGREGGKLATLVRRVKRYLKTGYFLDVGVLEECVRANVGDLTFEEAYARTKRVLNITISSTGGGVPSLLNYLTAPNVLIWSAALASNATNHTLYAPITLQCKTTSGKIEPWHVATPSSPSHINDSTKSPPPPPPPPRTVADEKDSPLARIAELFNVNHFIVSQARPYLAPFLRSDLGHTSGSPAAAHVGGHSGGMANPGSWFGRLSLNRGTGYFTTPLLRLMLLELQHRLSQLDTLGLLPPGIRRFLLDEHVPGASLTLVPDIALGDLARLLENPTAEAVEGWILRGERSVWPAVGALKVRCAIEVELDRGYQVVRRRGPMDGPVGPGGGWGGVVGGGGLGGKGKKKRRASSFGSGMVLGGTAGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAH4</accession>
    <name>A0A6A6PAH4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TRAPP trafficking subunit Trs65-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_418781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAH4"/>
    <dbReference type="OrthoDB" id="5345392at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055420">
        <property type="entry name" value="IgD3_Trs65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024662">
        <property type="entry name" value="Trs65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159:SF1">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12735">
        <property type="entry name" value="IgD3_Trs65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="668"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="823"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="882"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="domain" description="Trafficking protein particle complex II-specific subunit 65 IgD3" evidence="8">
        <location>
            <begin position="434"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="483"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="907" mass="100818" checksum="EBE2148B96ED0689" modified="2020-06-17" version="1">METSGPDTKPRTSSEFVDHSILEAVVPDTTSVDIEQLLSEWDGELERDRSSLLPFVPQRQFLLFDELVSVYVVLRTPYSDENNLKSYLLRLAISLEAHAVGTQTVPHEATGEAPRGPPPQAKEVLYSETIKESEEPLVIARGSQSSEEERGIPQHIFALWKLDVFLSHPRTKIQRPSLYFVCSASLRPAEHISPSIIEEEYLPSFVWQAPNLLQSFSSDPSLDGVQPRLSALRIQKVAPTAHVAKDLSRPLRTESRRLYRFAPAFLWRIRYSRPHASLSDEAVVTSLDFDFTTFAGCDIELEDIGVEIEGGGRIEPLLPFDKSAFGRTYHSGDQTTFLYKLRPESGVSEETKPKQHHQQSGPSHMLDLKIHATAIVNKTCKPRVRISWRTGTDMSGIYPSTQQAAVSRLQAILSANKQLPKPDSLPPPSTAGSQQDSSTTTSTSPDLGVSITISGPDSVRVGEVFRWDLFFLNRSGRDRKLAVVAVPKRRRHGHESSRKPHDSKHSLSSAGGPAGGKQDGAEVMDVAGAVVDDNVLYVMQKSAMLEPAEVICLSADVRVGPLSPSSCYSTDMKFLPLSTGVLKIDALRIVDLGSPGASFRPPATEAHSQRAHPVPCASRRTLPHSLTSTSLHEVSSTLAVLWNSRPPAPTMIENQRRRLLRALNSRYIYGRIPLLHCLIFLIQMAVVSILTRRFNNYYASRPVLTTMITNAVLGGIADTVAQSLTAIRQRAMRKPGGVTRDDFIAIEIHELDKKNPYPAGEIIPENRRLPPPFDFERLTRFMAYGFIMAPLQHKWFGFLSRTFPVTKEAGTIPALKRVAFDQFLFAPIGLAFFFTFMTVAEGGGKRAVTRKFQDVYVPALKANYMVWPAVQILNFRVIPLQFQIPFVSTVGIFWTAYLSLTNSSEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBK5</accession>
    <name>A0A6A6PBK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBK5"/>
    <dbReference type="OrthoDB" id="2011986at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="548" mass="61954" checksum="025B8646C4DB0DCA" modified="2020-06-17" version="1">MTESPFMRAPLEPREQPILDKLLQARAALELLKQDKSTYVKSSDVLRLYNAVVDQVVVLNEIRSTGNKRLEQNRVDTVLDDCFQLISLAFLTIGKNHEAPAVYAALSTIKRLLDHLKEAAFFSSKDLDSISSRLQDFRKYIDRGREGYSPHLITLLENRIDMCQATLTELQDALAPLGPELSPHYEKLVSILRSLSACNTKSKFPTQEVNDLHAQLKEVEASLGPIVENQQPLSEKELLDLYYKKYQDMQIEPGSHQTGKIIVNNLMIRCFLWVDIIKKKRGRIDERFQDTFDKLNHIKMQLERLSLTHAWSLRETDLYSYQRQLDRIDESRVDGNFLDDQGQPADLHAQRTLLYLLRKSYALIYHLIISSEPVSEALVPIYNQLLTLRRCLLEVRKSGGVSSPRELYPYSMKLNSIDNMRNDGKFMVGEDIPDGQAAVTQLLEECFDMAYELRSAAEEEEEREEREDAAVAEAERKADEESGERVRVEPGAEPGKNGLKAAAAGGSESEDEDEGLDEGVEIKAKERSGSGGGQEKGAVMRDGDVGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC34</accession>
    <name>A0A6A6PC34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_89527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC34"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="233" mass="24933" checksum="A759648E97235627" modified="2020-06-17" version="1">MVLYPVSYATACLLIPNEESVICASVTERASCPGQELLSPEHLAPAVASRPIGLQRCLRPKMLCGATCRIQYLGSTVVPSHGVGFANAALAIAPFLKFRSGPGTGRRRQRHCSGPAAACFTSFIAGLHCFEAAALIVLCFHSLPCQPACLLPAALGRLRYFLVLAAPHIPFFRFLSLIRTITTLLLSALLPSASLSIPASFSRQVLELDDAETRCAVRGSPGRRSYEPFGHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC50</accession>
    <name>A0A6A6PC50_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC50"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="23692" checksum="1375885AA424C350" modified="2020-06-17" version="1">MASEKPARRPASVNLSLLVCPRLPLRSLQPTETPGALSLSRSRSRARLSSPAIPIQARDCCSWSGSGALSEALQFGVDEIRSGREPVGARFRCWLRLPGAGVVVTGKERRLGTRVIRTAGRGRGGTEGESARGQTRGLTTATAPGASPAKQPRTELTARVKQTTPRAPATDTGSSHQASKQAKRDGAEVNEERKPSEAGAKDAEERAAAFVDARSGIRNGLTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC81</accession>
    <name>A0A6A6PC81_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_334081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC81"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="21187" checksum="8139E48B9F3C6054" modified="2020-06-17" version="1">MMANGGRQVPRQLYGELNKLLRERRALIAQLEESGLPSEEREGTDEVEEFRREVKARKRDFHERIRSEYGPASVRDLRSTEDMARARVRELRAIRGFMEVLVPSMQKLAGQIESAGGALSPARASGAAPRAPSPGDRSRDPARGSHHEEGRRLEHQAQPVRLAGGVRGEGREGVPPGPPRTRSGFWFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCN8</accession>
    <name>A0A6A6PCN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G protein-coupled glucose receptor regulating Gpa2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_93415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCN8"/>
    <dbReference type="OrthoDB" id="100006at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022596">
        <property type="entry name" value="GPR1/2/3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11970">
        <property type="entry name" value="GPR_Gpa2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose receptor Git3-like N-terminal" evidence="6">
        <location>
            <begin position="28"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="G protein-coupled receptor GPR1/2/3 C-terminal" evidence="7">
        <location>
            <begin position="275"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="349" mass="38242" checksum="97A107D73C8C8CF1" modified="2020-06-17" version="1">MAALAVRTVLSAPLTREGNKIQSKAILAVSILSAVGAAWMIVSFMVFKALRSFRHQLILGLAISDFCMAANFCLSTGLNVSGRMIGDPAQDKVCSFNGFMTQVFVIQTDYWVLTIAACTFLILANYRKQSMWIQDHRIYLWCIPWVFSSLWAGLGLGLAGYDDIGAWCWFTSDKVRLLVNFLPRWVIIAIILCIYTRLYFIIYRAHSRFSELDAEVAADIGTGSGALEGTLRSSTELLDSGGSKPATVGEGASVGQGENVDVARGSVAKPNSELKRIAGKMMIYPLVYMLIWVIPTSIRIYQSVSGQSAPLAVATVDKACIVVQGFADAIVYGVNESSLAAWRDRFSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD79</accession>
    <name>A0A6A6PD79_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_383021</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD79"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000001">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000004">
        <property type="entry name" value="Cleavage and polyadenylation specifity factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="12">
        <location>
            <begin position="36"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="13">
        <location>
            <begin position="264"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="14">
        <location>
            <begin position="577"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="658"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="748"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="807"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="906" mass="99124" checksum="2307F9C174D89E63" modified="2020-06-17" version="1">MAAKRKHAALAPVDDDPVDPSDELMFLCLGGGNEVGRSSHIIQYKGKTVMLDAGMHPAYDGLQALPFYDEFDLSTVDVLLISHFHIDHAASLPYVLAKTNFRGRVFMTHPTKAIYKWLLQDSVRVGNMNSSAENRTSLYTEADHLNTFPLIEAIDYYTTHTISSIRITPYPAGHVLGAAMFLIEIAGLKILFTGDYSREDDRHLVSASIPRGVGKIDVLITESTFGISSHVPRAEREAALMRSITSVLNRGGRALLPVFALGRAQELLLIFDEYWWKHPEYRRFPIYYLSNLAKRCMLVYQTYISAMNDNIKRLFRERNAAAAAASIEAQEGGGVDGKATQPGGGEPTLAGPWDFRFVRSLKSLDRFEDVGGCVMLATPGMLQNGASRELLERWAPDPRNGVIMTGYSVEGTMGKLILREPDQIQAVMTRQGGGWGGGWNAPRGKIAGQQGEIMVPRRCSVEEYSFAAHVDGQENREFIEEVGAPVVVLVHGERNNMTRLKSKLMSLNADKPVPVKIFSPANCEELRIPFRTDKIAKVVGKLAEIPPPTLSSLAIRPASSHTDEANTSQQNGNTEVSPQLVTGVLVQSDFKMSLMAPEDLREYAGLTTTTITCRQQLTLNAAGVALIRWALEGTFGHVDERTEVDEALAGKSDGVVNGSGKVKKEDNQSDECGMEVEKNGEREEEAADEEIKRTVTCFRIMDCVEVRCGKGGREGAVEVEWEGNMVNDGIADAVLAVLFGVESSPAAVKQSSAKHSHPQSPPSTPLALRSPNPHANLTPSVRFDRLCMFLEAQFGPNITPLHKPRMKAPALSSTTAPPSPGNIEVETAGGTTENAKEDDLTAEERAEIGRLHALGIPVPGVEIQFDKHTARVWLEDLAVECANGVLRDRVRAVVERAAETVAPLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDA2</accession>
    <name>A0A6A6PDA2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_330040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDA2"/>
    <dbReference type="OrthoDB" id="2190947at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.30:FF:000003">
        <property type="entry name" value="Signal recognition particle SEC65 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="243" mass="26763" checksum="C0C8DBB57021AFBF" modified="2020-06-17" version="1">MSHARVEEVSDSDSDPGEMDPSDFDPASFARASLMQPTDVPAASSPPPQPLRQPNQERAKRWQCLYPIYFDSSRSRAEGRRVGKEAAVPNPLAREIVDAVHSLGLNFTFEPTKRHPKDWANPGRVRVLLKDENGAKVARNVNNKHHLYNLVSAYLKLHPATMETPLRFKIPGLPPPKDPSQGPAIPRGWKMNSILPLHSAALGGSGVSENFFKEMMAEMQGESPGASGSESKPKKKDKKKGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDD2</accession>
    <name>A0A6A6PDD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_295254</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDD2"/>
    <dbReference type="OrthoDB" id="10259843at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="303"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="488"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="710"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="653"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="710"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="731"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="762"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="782"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2461860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="797" mass="88295" checksum="F8E8598EDD5FBFFD" modified="2020-06-17" version="1">MDDEFVLTISDDDSIPNVEEGDKLELPLVQPSKKRKRNDRETIVNGVGKKESKSKKAKKNKKQGGQERGSEDEEAENQDWVGRGEDDGALASDFEFQVGDMTSGIVKDFDGWGSDGQDDERMRGDKKAPDIEDIIARRRRQKEAKKAKAVAQMPKEEDEDENEDTGSFDEFPDDEELLADDAFGMGAESGDEAENSISGSEDNSGHDDEEGTNAEDDDESVASPVGHPEDDAESSSEEDERDDPVEVERRATFFAPENNIKGQTPPSTKTSGSFHEMSLSRPILKGLAAVGFTEPTPIQARTIPVALHGKDVVGGAVTGSGKTAAFMIPILERLLFRPKKIPTTRVAVLMPTRELAVQCFSVAKKLAAFTDISCALIAGGFSLREQEATLKTRPDVIIATPGRFIDHMRNSPSFAVDTLEILVLDEADRMLEDGFADELNEILTTIPRSRQTMLFSATMTDSVDKLIRVGLNRPVRLLVDAKRQTVHGLVQEFVRVRPGKEDKRLAFLLFLCSNVYTDRAIVFFRQKREAHRARVIFALCGLRASELHGNMSQEQRISSVEAFRSGATSHLLATDVAARGLDIKNVSTVINFGAPQTHEIYLHRVGRTARAGRSGRACTIAAEPDRKVVKAAVKAARAQGAKIASRTVPAEAVDEWAEKLNELEDEVEAVLKEEKEERAMQGAEREMHRGENMIVHEKEIFSRPRRTWFESEKAKKEAKAKGWKELNAAEEGAKERKEKKKLSGKEKKKLQDRDDRLGGKGGFKKGAKERGHKVVPKEKAKEKKAKAKANRAKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDK6</accession>
    <name>A0A6A6PDK6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_278618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDK6"/>
    <dbReference type="OrthoDB" id="7295497at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="16"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="95" mass="10891" checksum="1C0FEE6B322B40CB" modified="2020-06-17" version="1">MTSAELAARNSQAGPHKCERINPTTGKPCNVVFSRPYDLTRHEDTIHNARKQKVRCALCVEDKTFSRNDALTRHMRVVHPDVDFPGKHRRRGARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFH3</accession>
    <name>A0A6A6PFH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_331451</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFH3"/>
    <dbReference type="OrthoDB" id="5399138at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="17"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2462449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="508" mass="54835" checksum="08A5B1D47BA7823A" modified="2020-06-17" version="1">MKLRGVELRNPPRYVTASILCSMGGFLFGMDTGIIGPVTVMESYTSEFGSQAATIHGLIVSSILIPASISSFFAGRLADVLGRPKGIAIGALIFGIGAAMEGAAVQIAMFVVGRIIEGIGEGLYLGTLIVYICEISPPSQRGPLTTGPQLLITVGLVAGFFTCYGTGRMNSSMSWRAPYIVLASLSVLFANASFFGLPESPRWLSLRGRKAEAVYAWETLGVNPADREKAEDQYETPLVEDRNAIELRSRTSTDGRRHREPVKDKVSFFDVFKRDVRARTLLAVFMMGMQQMSGIDGVLYYAPLLFEQAGLASSKASFLASGVSAIVIFVVTVPALIWCDKWGRRRSTIYGGLGISATMFLIGGLYAGKAVHAAYGAGRWVVIVSIYVYTVIFSLSWAIGIRIYSAEIQPQRTRASATSLAHGSNWAANFLVALSTPILLANSSSGAYFLFGGCTLVTAVVCWVFMPETQGRSLDEIEEAFRSRMSESKGMFKAIRKVLARAPVTAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFS1</accession>
    <name>A0A6A6PFS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_330803</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFS1"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2462223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="297" mass="32079" checksum="3ABAE9537AF6EF49" modified="2020-06-17" version="1">MDPYSAEGELVNIHNAFHQGQYSAVLEFDTSSFSDSNQLPARVLKLRAQLALKQYDGVLAAVSKEASSVPDLAAVKTLAEHLKAPADEAPVEAAAKLADKEGDNLSVQLCCGTVLAGVGRAEEALALLSKHQGSLDAVALIVQVHLQQNRLDLAIKEAQQARKWAQDNLLVNIAESWVGMRQGSEKYQAAFYVFEELAQAPATSSVRTLVSQALAELHLGRAEEAEAALKQAAEADSKDADVIANTIVLNTIQGKDSTELKENLAKVDPGHKLLLDLNEKKELFETARAKYTPKFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKQ1</accession>
    <name>A0A6A6NKQ1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001713">
        <property type="protein sequence ID" value="KAF2452292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKQ1"/>
    <dbReference type="OrthoDB" id="6627536at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="75" mass="8464" checksum="9670D838CDA0E13A" modified="2020-06-17" version="1" fragment="single">EFHVVTSSRNKFSLFFLGPGQFINHNCEGNAELQPVNNGMQIIATRYIQVGEEITVKYGNHYFGKDNCDCLCTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLV8</accession>
    <name>A0A6A6NLV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLV8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="95" mass="11503" checksum="72A19EDA4079C832" modified="2020-06-17" version="1">MGLRSLRLMLLPLLLIPRRRRRAWHLRKRHSHNNSSSSSSNRIRICWACRRRGPPSRVRTATRRWRTCRRATRRATRKAMRVRKKSSRMGMAMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLW4</accession>
    <name>A0A6A6NLW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_388439</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLW4"/>
    <dbReference type="OrthoDB" id="342981at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15850">
        <property type="entry name" value="SNARE_syntaxin18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019529">
        <property type="entry name" value="Syntaxin-18_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10496">
        <property type="entry name" value="Syntaxin-18_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="291"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2452730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="381" mass="42026" checksum="8AC47AA62141570B" modified="2020-06-17" version="1">MDLSPIFNESLAKHNVPPLRPRPFRLADLDEFLKEAYRINTHIADLTAYLSAIRPSYLSASSASAPSSSRRYHQPHAPSRRPHAPPRADSSASPAGPGAAHRPTHLTDAQRDQIDAETKALLRELNAGIAALAEAEGVRRDASRAVRLKKRRRVGLGALGRWAAGGGKGEGLDEEEEKGEEEGRDEAVGAFRDGVVWYLREKLRAAGERQSEMVGRRLGEEVERRKNELNRFVGSRGGKIDGLAANGFAGGEKRGSVDEGKATVAGTWGDDDEELSEEQMQTFARENQDMLRQYEDQLDQVRTAERSLVEISELQSTLAENLTTQQEHIDLLVQDSLMTAENVGKGNKELKRASERASTARVIFYATGAFCFTIVLWDLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM10</accession>
    <name>A0A6A6NM10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_294993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001715">
        <property type="protein sequence ID" value="KAF2452273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM10"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5029036103" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="303" mass="32073" checksum="D6FEF69F793FEA5D" modified="2020-06-17" version="1">MRALLTAFTSAIFALVAGSASIQSRQVAAGSLQQVQNYGDNPAGVPMYIYVPRSLGDSPAIVVAIHYCTGTAQAYYNGSPYAQLAEQYNFIAIYPSSPHSGTCWDVSSQQTLAHNGGGDSNSIANMVTWTLDQYGADPAKVFVTGSSSGAMMTNVMAAAYPELFAAGTVYSGVPAGCFYSQSGAVDGWNNSCANGQVQASPQVWGDTARAMDPGYEGAYPAMQIYHGSADGTLLPPNYDETMKQWADVLGYEYGSPEATEQNTPQNGYTTTVYGPKLEGIYAQGVGHTVPIRGDDDMRWFGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMB1</accession>
    <name>A0A6A6NMB1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001709">
        <property type="protein sequence ID" value="KAF2452474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMB1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="180" mass="19588" checksum="B3FC9C7104268348" modified="2020-06-17" version="1">MVCTPQTDGPAETDSSSRRSHVEPEPPAAGFLSRDTLVPDCLRRRPHRELRRLLRPEAARHRALPGAVPVDAGGDVSLDHRALPAAAHPGQGPLRGAPLRHGRVDRDIVRAPAADGLRVADGPLPAGLLERDVSGHGRRHRHGRHVLHRRRRDGVQPQPLRVLRSPRLHRRGTGGGGTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NML0</accession>
    <name>A0A6A6NML0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit J</fullName>
            <shortName evidence="5">eIF3j</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 30 kDa subunit homolog</fullName>
            <shortName evidence="5">eIF-3 30 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HCR1</name>
        <name evidence="7" type="ORF">BDY21DRAFT_388570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit J family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NML0"/>
    <dbReference type="OrthoDB" id="20381at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.60:FF:000003">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03009">
        <property type="entry name" value="eIF3j"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="276" mass="30970" checksum="97B66C2B7094A756" modified="2020-06-17" version="1">MAPNKWDEEESDSTPPTSPPAPVVRRSKFDDEEDESDVIESWDAAEDSEVEREKAKKAAEAKAKAEAEAKAKHKSKAQRIEEHRQANLRRRQMEEEEESSEEEEDEGERRARLRQQEKDSDLAHAEDLFGGLGVADNKTRRTAAKPVTLADPADPANTIDLAALPIFNPQTKDQFAKLRETLVPLLSGNAKKAHYALFMQEFTKQICKDMASDQIKKVASGLTTLSNEKMKEEKAQDGKKKTKAAKTKSSLVAHRDTVYKADTTAYEDDFGDDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPB3</accession>
    <name>A0A6A6NPB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_121150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPB3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="197" mass="20356" checksum="11EEDAF6BEBA2543" modified="2020-06-17" version="1">MPSGFCWSATSFSGLTTGMTAILPLPPNQEAVGISCAATQPCGVVVVVVVVVVVVVVVVVVVETPVTNVAPALSSTGVESPTKATTYSNTVIPVDRQGAAAKLLPPFEPRCGAATGPPTTGEKSRLSKSGSPSLEARGPVAAEANERSETGVWSLGGRQQTPVSALVACACARYVRSRRVMREPCTECQARVFLCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPK4</accession>
    <name>A0A6A6NPK4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromatin remodelling complex Rsc7/Swp82 subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_356343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPK4"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF3">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="537" mass="58527" checksum="741504AAF910CCC8" modified="2020-06-17" version="1">MGRRPRAAALASAAALRSASTQQKIDDDESGTDAGQADVPREENQDDAATGTPAQESEGATQAEPEPEPPAEQYVPQPVVRRKRLGRPPKNRPPDWNKTPEPTEGEVIIPIKRRRGRPSTGVGGGSTRGGRGGRGGSSQVTRVPIDKEGNMMDVVNDEVALPEDPEGETKVDKNGNLLGGRDYRVRVFTITGRGERLYMLSTEPARCTGFRDSYLFFTKHMQLHKIIIDESEKYDLINRDIIPHSYKGRAIGVVTARSVFREFGARIVIGGRKVIDDYQVAAAKARGGEGELADPDDHLPPPGEPYNKNQYVAWHGASAVYHTGQPSVPTQVGKAPVKRKVNITSNNWMYEHSLAASRFNSQLAAFRRETMDGVYNPHTNQMHYPEITQPTHARWEEVPPPEEAKEPNGLPNGVTNGAQSHLTNGITSSVTNGEHPNANSAVGSPSATKTIFEPVPGVISRNFLITDTCMQSAPINNIGRSGLADVPLEVADCLPPQCRAAFEQAKAREIEWNEQWKSETEAGCRGKLKIGLTGHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ64</accession>
    <name>A0A6A6NQ64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_292373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ64"/>
    <dbReference type="OrthoDB" id="3778324at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="126"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="559" mass="61586" checksum="82B7D9A34404E005" modified="2020-06-17" version="1">MSPPDSVADRLVELQTLSQLFESRFERDGNDDDLRHAVTHLGSALAECKNAEESESLRSSIAALKLRLNEVVVPTVLEIPFDQVSDEPVSIAHAQPCKMRFIHCRSLADRRSLRVLEFASIPPGRYVPLSYVWKGLGAPAGQPGSSFMTIRGAGDADPISVSVLRLCCTAALRHHVELLWLDGLCIQQESPADKNWQIQRMYDVYRLSALCLIVPGGLAQLAPLGTPTAWIHRAWTLQEAVAPPRSECLFAWDEGDTMLQAHFTLILREIGPGAAIAEYEWLLQMCLLGRAGFQSDSDRKTDVRLLGGEQDQFQLRALVGAHDLVGKEGLANAIWRSSISRAASRPADKVFSTMGVLGVTLDPSQFAPDDWRGATIALMQALLNQGKHAEWLCIAPELGVSGEIGTLPALPDTGPDGRAVADTPQGRRSVSELVHDSWWMLENAPQGSMSDDGYLEFHTRMACIQEVDSNSDCERSFSSVTGKDWKLLPKSDEKVLAAFIGRKSAYLNATYGSFYNPANRVLMLLEEAALGKYRVVDYAFVEEQIIKGDQWQGKTVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQD8</accession>
    <name>A0A6A6NQD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_374833</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQD8"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="599"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="744"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="808" mass="90179" checksum="7F432E2F09F2FDAF" modified="2020-06-17" version="1">MALRPKSSIITENSVTSTSSEESSLKGVKAKTDTAKVTSSEVRPDDSPVDELRNRLSRPAWDLNLPDDFKTTSSSSLWEEESRANGGQIEENSPYEEVRAAVPNWDEEMPANTIRAWVLGMTLSIIGSGINTLFSLRQPSISIGAVVAQLVSFALGKAWARWLPSKQRTLFGIRWNLNPGPFNVKEHAVIIVMASVSFSQAYATDIIIAQDKFYGQNFGIGFQILLMVTTQSIGYGIAGFLRKFLVYPAAMIWPGNLVSVTLTHVMHEKEVKPDPNVLGGKMSRFKWFGVIFLGAYLYYWIPGYLFQCLSMITFVTWAYPQNPVVNQLFGGTTGLGLIPLTLDWTTIVGFLGNPMIPPWYAIANSMVGVVIFYIITTIGLHYSGAWYARFLPIGDSLTYDNTGVEYNVSRVTTPRLTLDEAAYAEYSPLLLSTTFALTYGLSFATIASLVVYIYLNFRHVIVAQFKNAKTEKPDIHMKLMQKYPEAPIWWYAGLFLVMLALSYVTVLAYPTEFAWWAFTFAIVFSTVMTLPVGIVQAITNHQIGLNVITEFLMGYMQPGRPLALMMFKTYGYITASHALGFLGDLKYGHYMKIPPRTMFMVQVVGTIISCFVQIFILNFALDNVEGICEPQQAQRFTCPGARVFYSASVIWGLLGPQRMFSPGQIYSALLFFFPIGVAFAVALHFAAKRFPNTPLKYAMAPLILGGGASIPPATPFNYLTWGAVGFIFQRFIRRRYFAWWARLNYLTASGLDTGLAVSTLTIFFIFTLNQIQAPQWWGNTVFKNTMDMTGTAVQDKVASGNSFGPENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQY1</accession>
    <name>A0A6A6NQY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_112530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQY1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22557" checksum="C85A260DDBFE8566" modified="2020-06-17" version="1">MSGRPTSSPWCGKLRRIGVKGHLEAAIHRAILRLERSSGREHGFKGWRRILPPGKVTSDGEIGRGRIRRRSFRSHEEGAAKPVIWGMGNPKWFMIREKANGPKSEPEQWAAQPRRSRAESSSDRIPIGGKTVRAVLTCSRDREGTIVGRTRTEASRSKYGAAEPPVRREMLDTAAVATGAAKRSAGEVKLEGTGDRDSRRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRB8</accession>
    <name>A0A6A6NRB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hemolysin-III related-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_374198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRB8"/>
    <dbReference type="OrthoDB" id="529367at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF130">
        <property type="entry name" value="HAEMOLYSIN-III FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="339" mass="36714" checksum="102748DF2FF631EF" modified="2020-06-17" version="1">MSGGDGIRQSKWAGREAVVDGKRKTKDSTLYLWSELPEWLQGGNELTLTGYRPITESVYECVLSWFYLHNESVNIWSHFLGAVLFACLPCYIFTTEIPPRYAVASTADVTVFSVYLFGVAICFCLSTAFHTLTNHSARVLTLGLQLDWLGVVILMWSATIPQVHYAFSCPAAAADSSSSADATAAAAAAAIPLRNLYWALLTAQAGACAAYTFAERFRDPLTGGRRAAAYAGLAALTLVPVGHAWARDGWGRRGAEREAAREKLALGWVGVTVVCNGLGAAAYAVKFPERWYPRRFDIFGSSHQILHVMVILAALAHAKGMLQSFDHVHSGGDTCDVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRH9</accession>
    <name>A0A6A6NRH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRH9"/>
    <dbReference type="OrthoDB" id="368909at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06168">
        <property type="entry name" value="LSMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034110">
        <property type="entry name" value="LSMD1_Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF5">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="10"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="115" mass="12709" checksum="1D1FA0E62FF0C343" modified="2020-06-17" version="1">MPDPAIEAGNLLANFLGKTLRIHTQDRRMFVGQMKCTDKDCNIVLALTHEYRMPSEDSVRAAAENTETDKFNVSMPHRFVGLVVVPGKYITKIAVEGIESAVVEAMGLKESDKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRS8</accession>
    <name>A0A6A6NRS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_366372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRS8"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="36"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="457" mass="49712" checksum="567A63B8EFC56967" modified="2020-06-17" version="1">MAAAIASLKSKLPGAEVITPEAPDYEQSIKRWSDACEERAAAVVKVANEDEVAGVLAVAQEHSIPIAVLGGGHSTSGASSTEGIVIDLRKLQKVSVDPDAKTIAAGGGCTWAQVDVEAAKFELATVGGTVSHTGIGGLTLGGGYGFLSPRYGLTIDNLISVRIVLADGSCVTASEKENPDLFWGIRGAGHTFGVVTEFVYRAFEQGDVFAGPLIFTPDKLAQAVEAANDIFALDIPDIVIVLGFTQRPGMPGPVVIAFSAYNGPEAKGRELLKPLFDVGPVMDMTRTMPYVEVNQLMNEGQDFGGRKQFGGSTFKMPMNPADVSAVFEMYLRFCEAHEKVSETAVIWENFHNGKLREVPDDATAFPNRGDYYNVGSVVKWYDPKQDVECRQFSRQIHAYIFEHGGVPKTKASEAVRHVSRTKAEDLFGDKVHKLRELKKKYDPKDVFHKWDVRRRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS40</accession>
    <name>A0A6A6NS40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_108152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS40"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="534" mass="59400" checksum="44BBD489C83AB6C0" modified="2020-06-17" version="1">MPPKRKAATGKGRRKGKTAPPEKGKGKASPPGDQTAAQERMDSLLGTVEDATTGPSAPRTQQDARGSRGDSGDGGGAAAAQPPEDDDKYNVVWYPDGTVDALPYERARHKHRIVRTDGEIEEWTSEENDVVEARTRARRIRPARGRRTATTRPQRTEHHHRLVNEDGDDVASWTSIDEPSPPPPPVFRRTPRKPAVVGAGDGDTDYESDVASLLGLETSGADPVAPHNTHVPEYDRVVPWQQFHELDEEIWHADLLDEFTFGESHFARNLISAQIERALKHGAEREERARKRRKTGADAAVDVEPDDASDVFQLVGGDDLNDDRDLDAIEDLLEREAAWAERLEERAARQEERDDFLASTNSFSRFPLPPLPPADVWDDLKRRKVIPSHEPKECEACKLLPEEWRDLSVPGVWVYEGKRFQTLHQGRQEWRPAPAVEEVVPDDESERLYENSPASPPLQPQAETPPQPTVSGATGIATPSTVRTTVRMRKRKGKVTKTPRTPNAAPAVPDIYGSIVRTRGQTKRFQHTAGHDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS54</accession>
    <name>A0A6A6NS54_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_109692</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS54"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="72" mass="8700" checksum="7B2C7CD1CE3922DA" modified="2020-06-17" version="1">MHGASFFFTFLIYFWEIRSVWDREFSLLFIELLCNYFPGMLLARQPPLGELSAYHRRQSNRCRSPRRKVPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS91</accession>
    <name>A0A6A6NS91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS91"/>
    <dbReference type="OrthoDB" id="5215637at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025533386" evidence="1">
        <location>
            <begin position="21"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="21266" checksum="DCBD71A2E2BEA8BB" modified="2020-06-17" version="1">MLFAFIATLLGGSFISLVAGQDPNAPCYFPGGQWAEDFYPCDIYAYPTTLCCPSGWTCFDDALCIITDEAASNSSFPMGTTYRGTCTNPEWDNDVCGDFCLNNPVSDNGGALVQCSSNTFCCAPDIEDGACAYDLASIFDTISSNDGTTIYVNYFNCRFISANGHEDIKGKQLVFNDFQQSFHDYFGNSHRNGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT30</accession>
    <name>A0A6A6NT30_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_351903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT30"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025395120" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="54" mass="5804" checksum="ECDA7203B9FDD4BF" modified="2020-06-17" version="1">MLRNMSTVMICFSLCFLAHGLATVLAHLLPSQAFISLPGNAPHPPRPILSPAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTE2</accession>
    <name>A0A6A6NTE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_77439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTE2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="386" mass="41134" checksum="498888C86C0D43E5" modified="2020-06-17" version="1">MRALDVKLRRGARRRGGVLDRGGIGGREDDGIHGKKVATRTSSNGHSVSACGCACREPSGRRRRPPVDRSRPKTHAGILFAIGSRSCYVPAHACTCGADGAYRERVGGVPKAPGEHRGRGDMEPFPFGLPLVLHRHVVECHGGGIRCPCINRPDRPCASRTGITEPFSSRAPRNDATPLERSKVRLAPVAVVRIGGRLRAPDPRRASSCRALVRARESERERERDVGERVSRKGSPSRALSIARSAARQATHPPGLSNGMGRPSTNMPQTHGQGPGSAAGGCEAVNNPRLTYIATTKIVAPTNGPFSHESARGFITVGGGRGPWVHLASLLAPLATGPPSIDVIQPLDSACLASGHEREPHFKSPRQHMTALLRLSQQDTALDARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTG3</accession>
    <name>A0A6A6NTG3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTG3"/>
    <dbReference type="OrthoDB" id="5093896at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="102" mass="11192" checksum="91B40E128DBD466C" modified="2020-06-17" version="1">MSSAPEQNGAPSTEPLEASLSTLAIHADDEINTYNDVAPALHVSTTFRYASNPDELEPVDIPVCCSFPLSVVFFLFFSPPPGVMEDYSSRKPMQEDARQELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTQ4</accession>
    <name>A0A6A6NTQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_373714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTQ4"/>
    <dbReference type="OrthoDB" id="5338512at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="54734" checksum="9B41C714D5770FC6" modified="2020-06-17" version="1">MHSMAVVLPASATNPTSLFQPRQDPSLCGGNDDFAQCEGDLPADFCCPADSSCLRLNAPDGILSVLCCPDGQDCDIIRPITCDPVQQNATLHPTNQVHSDDTDIELQTCGDRCCPLGYNCDGDLCIRVDNPAPSPTEQPSSGADAPTATSSSQPTNALGDSPEEDSDESGGGPSGRVIAAIVVPSLLGGALLLFLGQFLWRKYKASRKPRYSGDWGPVSRSVSDPIYQPQMSDRADFLLRRSSGGGGGGGNGGSTAPGSRSTADPERPANSGYQYEHEMNAVHGGGGTSSGGLGVAITFADQPHPAHQHHQQYAQQAQPPTTPPPQQDMPRGLFSRTPSSTSHAPPPYLRSEFEPSTAATTQDPFATPPRQQQQHRHHQPTGNTPPARSLTRRPTLTRNGPLGPTRNGSNASARERSHRPGHPARNGSQETIDVQLMTSQALEQSPLDRIRGLGGAGGRRSSNGGAGQAVGGGVGGSTNPGGLMPPPPIAEARGSGRSSFLSQHTTFTTLMENAGFKREETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTW3</accession>
    <name>A0A6A6NTW3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U6 snRNA-associated Sm-like protein LSm6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_416514</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTW3"/>
    <dbReference type="OrthoDB" id="268799at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01726">
        <property type="entry name" value="LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000037">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF1">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 15" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="9 15" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Sm" evidence="16">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2454884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="8664" checksum="5FD695F67E09C5A7" modified="2020-06-17" version="1">MENGAGEAKDPSGFLSEIIGAPVTVKLNSGVVYKGELQSVDGYMNIALEQTKEYVDGKLRRNYGDAFVRGNNVMYISADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUE1</accession>
    <name>A0A6A6NUE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_264687</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUE1"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23043">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23043:SF17">
        <property type="entry name" value="PROTEIN SIMILAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="233" mass="26680" checksum="8765CD3BBD123C46" modified="2020-06-17" version="1" fragment="single">METTFITIHDLSRDARILYSSDSIVDILGHTPDEVIGRSAWDFFHPEELPVAKELHSRGVRLDKAAVLAYCRIRNRQGDWVTCECCFSVVYDVMVCCTSIYRNPATDPARRHADAPVIRRIFSSSPKDPRYHMLTHLSGKFSMGPEDQTHEPRAALFLNRFTRTLTIMYATSGIEQIIGIPSEDMKGRSFYYCIQQNCLQDAVRCLEQAKGNDSIAYMRFFFRDPRQDDPPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUU1</accession>
    <name>A0A6A6NUU1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparaginase</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_289149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the asparaginase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUU1"/>
    <dbReference type="OrthoDB" id="542841at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009066">
        <property type="term" value="P:aspartate family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1170:FF:000003">
        <property type="entry name" value="60 kDa lysophospholipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.40:FF:000001">
        <property type="entry name" value="L-asparaginase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000284">
        <property type="entry name" value="Lysophospholipase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00057">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="8">
        <location>
            <begin position="14"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="9">
        <location>
            <begin position="253"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="537"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="539"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="565"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="595" mass="63011" checksum="8AD148F06C9DFCF3" modified="2020-06-17" version="1">MMDPFVDLRYPESRVLIIITGGTICMRPSEQGLIPATGFLKSGLAPRPSFNDGSYPEPLEIVVDDKSTRKAVQSLRTPVSAYDRRIRYCVLEFETLLDSSSIDAAGWDKIAKSVHRNYQLFDGFVVLHGTDSLAYTCSALSFMLQNLGKPVILTGSQAPMLTLQNDATDNLLGSLVIAGHFMVPEVCLFFDNKLFRGNRATKVSASAFHAFESPNHPPLAEISSLRTEVQWNLVYRPTVVSSFSLALKLDTAHVSCLRVFPGIKPEMLDAVLRIEGLKGLVLETFGAGNAPGGPDSAFVRVLADAVRRGIVIVNVTQCLSGSVSPLYAPGTALGQAGVVFGQDMTTEAALTKLSYLLALPDATPEGVAKQMSVSLRGELTETSRTHFQHPNGSLTPKMTALTALGYAIGAGNLAGVRDVMRGEPEWLLNDVDYSGNTPMHLAATGPSVDVLREFLSQGASVHLRNRQGHTPLYLAAAAGLAAHARLLLDAGAHLHLEEMAAARLQAGAAAGRKAAGGKKAGSRQRAERARVWRMVGVGVEEEEDGEDGDVDAEAEVEERRREGDGVGAVGEGVGGGGAATGDGDGENGGGGAPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUU8</accession>
    <name>A0A6A6NUU8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_289202</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUU8"/>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054080">
        <property type="entry name" value="TPR1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21889">
        <property type="entry name" value="TPR1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="637"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="CTLH" evidence="6">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="321"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="363"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="719" mass="78948" checksum="549C6AE60DD8C532" modified="2020-06-17" version="1">MGAIKYANGSSSGGKGALESNGSHANGSRSGAIVSSPSRLTEKRAALPPTFFGHDREEVTRILIQGLHELGYDGAATTLSRESGYELEGPVVAAFRAAVLAGEWAEAEALLFGVQRYGNADGDGGGGGLGGEGWPTGEVNIGFSKNRGKGIYVGDGAGAGSWPGYQHQQGGLPLAEAANKNEMLFWLRQQKYLELLERRDLDAALAVLRQELQPFAQATHDVGRLHQLSSLIMCASADDVRYQAQWTGAEGDSRAQLLSALSRYISPSVMIPEHRLAILLDQVKGGWISNCLYHNTSTSPSLYVDHMCDPDEFPLQTILELRDHTDEVWFLAFSNNGDYLATTSKDHTICIYETRSYKLVQRLEDHESGVCYVAWSPDDSKLISCAQARDNSARVWDVRTGRCILLLSSFTYPVTSAAWAPSGETFVIGSQDADAALCVWNLDGDKVFPWREDGLRVHDVAMTPDGSRLVVLLETRILVFDLASKDKLADFALDNVKLTSVNVSRNGRYMLVSMNDNKIRLMEIETGEVVQTYDGHRQTQFIIRSAFGGADENFIVSGSEDSRVYVWRTNGPLVTALDAHKPGCVNAVAWHPTDPRVFASAGDDSRVRMYVTFFFSSSYCLFCCESCLVWDFSLKRVLLFLCYAPIAIFLSCSLYSISQYSPSSLVLWNFPSVLLALVCLWAFLIRAPNFADAFGIRTSSYETVPVLDLSSIYLASITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV32</accession>
    <name>A0A6A6NV32_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase-promoting complex subunit cut9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_307076</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV32"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="351"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="453"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="605"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="646" mass="72110" checksum="E4C4FBA523F72F05" modified="2020-06-17" version="1">MEDFLREWRQDALNKHQYESAIFIGDKVLALTDDDQDAFWLAQVHFQTGNYSRVQGFLSRKDLIDNNPACKYLAAHSLIKQSKFDEALSLLGDKNPVHLISSPGSSRRKLQHLDSTGYGLVLTRNGTAKGGRVASAAAAPRKMERLDRAEDRDREDAQNIKFEAAMCYLRGVCFAKQNAFDRAKDCYKDAVRIDVQCFEAFDQLMKNSLMSPDEEWKFLESLDFDSITVGRDNGRGDSSSIAQEAADFARMLYTTRLSKYEHPTDFNAAVETLSTHYNLSCNPDILMAKADLLFTQCRFTEALDLTTSILSRDKYNFAALPVHLACLHELGEKNALFLLAHELADTYPGEPTAWLAVGTYYLSINRIAEARRFFSKSSMMDPHFGPAWIGFAHTFAAEGEHDQAISAYSTAARLFQGTHLPQLFLGMQNLQLNNMSLAHEYLGTAYELCQTDPLLLNELGVVFYHEDNLDDAISLFRRALDIASGIHADYRAFLPTRQNLAHALRRQGDYASAKKHFDEVLRLGGRDAHVFTAKGLVLLEMGDPWAAVGTLHEALATSPQDPMASELLNRALEECSSVAISGVEEEEEFERAINPAKSKLLAINAGASGGRKGKKRAEVVVHDDEDDVGDRRAGDSMMLDMEEEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV66</accession>
    <name>A0A6A6NV66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_349444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV66"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16811" checksum="5B861FF93C178AA3" modified="2020-06-17" version="1">MREGRNVKLGGLVVGLPVLSAVPRVNGESVVDMMSCQNGGLDRLLSVSFLWLWFPAMFLFYRSELVGGARSGRVLRALFSYLVQVLAREMRACIIPSIVRRLQTIILFSRRGWHGVRIGLETTPACVSASAYWALVYGYLSLLFCRLGAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVS8</accession>
    <name>A0A6A6NVS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVS8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="60" mass="6730" checksum="5B2B5F0CBB1A0290" modified="2020-06-17" version="1">MQQPASQPASWRQASPGARTPRHDAVGKRGRRLRVAPRLTYIVLFARPRVHSPDSGVKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVT4</accession>
    <name>A0A6A6NVT4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVT4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="68" mass="7445" checksum="DEF1B8244030191E" modified="2020-06-17" version="1">MGGGTSEMGESSAVLLRYLGVRGSELWGGEMYDGSMPRAGNVWLRGRWKLLPALVLFGWPRLCCCCCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVU4</accession>
    <name>A0A6A6NVU4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_306982</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVU4"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="9"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2455582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="232" mass="26123" checksum="805F8B3F66EB7911" modified="2020-06-17" version="1">MARGKLIVFEGLDRSGKSSQSLRLVEKLEADGHHVLHMRFPDRTTPIGRLIDAYLKGESNQDDHVIHLLFSANRWEASSTIHSHLAANTTVVLDRYFYSGIAYTHAKSLLSSTSSPSPPPSPLTLDWCTSPDVGLPRPDLTLFLDLTLEEAARRGGYGGERYEKREMQERVREVFGRVWMGEGDAGRKAGEFVRVDAGKGMEEVEEEVWMNVRDMWESVEREGKGVGVFEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW43</accession>
    <name>A0A6A6NW43_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_349480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW43"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="176" mass="18258" checksum="0963AEC4E0D80928" modified="2020-06-17" version="1">MNVPGMPGALGGAKAGLSDQERQMVKFMESAVESCPFKTVMSGGAGFALGGAFGLFMSSMRYDTPLTPAGNAISQLPMRQQLREGLRDMGRSSLRSARNFGLIGAIFSGTECCIEGFRAKHDLANGVAAGCITGGALAVSGGPQAVGLGCVGFAAFSAAIDWYMRLPEDEVRKPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWC9</accession>
    <name>A0A6A6NWC9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_372923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWC9"/>
    <dbReference type="OrthoDB" id="4161186at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="2">
        <location>
            <begin position="53"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="184" mass="20314" checksum="18C1D5EF08690384" modified="2020-06-17" version="1">MEEIPDELEMMLKAIDTRFSRGIRAISKQYEDEIASIKTGALGAINAYDFVYADPDDLPGPSPTPQQCAKAVWLAGRCEEMGCSEAAWNSSVHNYVLDLALYTKPFMDRVYFFNCTTAQIAPSSLIPPSGPTTASSGKMTGFAITIELSDRFKEAFNTRFCGKTDRSVNHSPRTADTLPDRSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWQ6</accession>
    <name>A0A6A6NWQ6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_70609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWQ6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="266" mass="28859" checksum="E777611227F5B9C6" modified="2020-06-17" version="1">MTHEPVQRRGTVGAMAAGQSGDGEDEDGPGGAWRKAGYGAKERGRDTETTTRSAGARAAAHEAEGTDEGGEQSQDAISTQVSEDTELPPAPRIGLCSYRAGHVCASASTAQRARSHAPGCADARPPCPFANALVYLAPCVAHTPYVAHDLLPLHGAERVASLAHWAPRETRPDAGPLGAVEKGSRADGWEDGEAVRRRRIVLVEGRRRKQARQTVRDGRKWVGNGDEGGVEVWDWRCLEEVAEWEGGQGRWEGELEVILERWRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX63</accession>
    <name>A0A6A6NX63_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX63"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025391550" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="8995" checksum="4EE6FF896618065C" modified="2020-06-17" version="1">MLLLLLGFEAEAGWCDFGPSEGRGVLAGRGRYGGSGWGIKNGGVLNAVEDEEGGRPGDVLRRNRMPDWIGMMDDGLGGSGRWWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXC9</accession>
    <name>A0A6A6NXC9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_287536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXC9"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="456"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="686" mass="79124" checksum="15434F8A7439188C" modified="2020-06-17" version="1">MSQLENSPSANPHYLVIHKVHCFQQDTNHKNHETTTFLDTPRLFEGDSKVSPLRGTQKFHNVDHYLEDHPEVNFLVERKYSCEEYHELKRTEFERLQIPTVDPETALQLRPYLFVLRKSVEPATPGNETLTVLSQDLRSAIDAMKAHFSANFVNWVDDMRFRLDAPYLPLHHIKSLFNDWAPQLLNKEELKQARLLFEYVQSSYGADYEEADELFSKGQVSKTHLYTLFLPGETVVTYEDGQPLAFSLQSCSRISGRHGITLRCYNWDFDGAFHRAQHSIEVYWPKSDPAIVPIDSLEAYPLRSDRTGLEQRLRVRGQTFWGLRKGKLVSYESDSRTFEMPVTIPRYMVDISMHRQLSDDSDIPEPRDDLGQHAMDNDTPPEDPFVLLLPAYVKGFGFHDKKWRNLLVEDICPVQWNKRAFRQIILAHHKKELIEALVSEHVAMVYPADVVEGKGNGLIILLHGGPGTGKTLTAESVAEIAEKPLYRVTCGNIGTEPETAEKYLESVLHIGSIWKAVVLLDESDVFLEERSQMDLKRNALVSVFLRVLEYYEGILILTSNRVGLFDEAFKSRVQLALHYPPLDENGRWKIWQNILFLLRNEPGSRSINYEELENRIDSLARHSLNGRQIRNAIKSARQLANHRKQTLDCSHLEQVISVLSEFERDIADAHGHSDNEWAKFQHFRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXW4</accession>
    <name>A0A6A6NXW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_372430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Binds to F-actin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the WD repeat coronin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXW4"/>
    <dbReference type="OrthoDB" id="1850764at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000197">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="12">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="116"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="214"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="439"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="605"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="651" mass="70686" checksum="B22CFADBCFCE580F" modified="2020-06-17" version="1">MSGRFVRASKYRHVFGRSTKKASNRSSAPSAIADGSAAHRSNATTTSASPRMLGTPTSSRQDAATDQRDGSRPLTTNHAQANPHYISVNWESSGGGAFSVIPLGERGRIPEHIPLFRGHTAAVLDTDWSPFDDNLIASASEDGKVFIWKVPEDFTLHTDAEEPADVSPVSKFTGHSRKVGHVLFNPSAENVLASASGDYSIKIWDVESSAAKLSLKHGDIVQSLSWSANGSLLVTTCRDKKLRIWDSRQQKPAIEQPGHPGAKNSRSVWMGEHDRVATTGFSKMSDRQLGLWDVRTPGDPIGGFQILDSISGVCMPFWDDGTKCLYLAGKGDGNIRYYEYENDKFEYLNAYQSSEPQRGIAFLPKRGVNVHENEVMRAFKTVNDTYVEPISFIVPRRAEVFQNDIYPPTLGLKPSMSAANWFAGNEGLPPKISLESVYEGEEPTVLPPESYKPAVSAAQPAPAANAPPPKKEEPKPAPTSAPAAARSPPPSMKENKASIAEMANKYADNEPEESEEDETSSFEEVPKPVERPAQKVAEPVKPSLVAAAAPPQPKPAAQPTLTPSSPPQTAEAPTPRAPAATAAAEGIKGTLAEIKSMLEMQSKAMTTQSDQIAQLTAEVDTLKTRLGEQRSDREKDERIRRLELELEEAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY53</accession>
    <name>A0A6A6NY53_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="6">M1Pi</shortName>
            <shortName evidence="6">MTR-1-P isomerase</shortName>
            <ecNumber evidence="6">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRI1</name>
        <name evidence="7" type="ORF">BDY21DRAFT_321956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="6"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY53"/>
    <dbReference type="OrthoDB" id="2461at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.420:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10470:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="entry name" value="translation initiation factor eif-2b, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004326">
        <property type="entry name" value="PRK05720.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF1">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="404" mass="42176" checksum="E21552FA0D09D9C8" modified="2020-06-17" version="1">MVLEAIRYSRGALEVLDQLALPHATRYDAVRSSRDAWQAIRSMRTRGAPAIAIVAALGLAVELEALRRDAALPPAAADVAALVDDRLAFLVTSRPTAVNLADAARKLRRVAREAAARAGDGGGGGGGADVADAYVRAAERMLADDVRDNEAIGRHGAEWIAARAGGDGDDDDDAALSVLTHCNTGSLATAGYGTALGVVRALHASSRLRRAFCTETRPYNQGARLTAYELVHDGIPGTLITDSMAASLLALRGRADNIAAVVVGADRVAANGDTANKIGTYALAIAARRHGVKFVVAAPRTTVDLKTASGAAIVIEERPAREVTTITGPTVDADPTTPAQTIKIAADGIAVWNPAFDVTPAELIDAIATECGVVEKGEDGEFDLEKLFGQEEGDMGREMGRWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY95</accession>
    <name>A0A6A6NY95_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like-conjugating enzyme ATG10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_271634</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY95"/>
    <dbReference type="OrthoDB" id="4089664at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061651">
        <property type="term" value="F:Atg12 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="220" mass="23401" checksum="2C5A9CC67B9D3227" modified="2020-06-17" version="1" fragment="single">LVARFPSLSSAEFAAACRELVSRFAARGELQCRWIYAAFDHDCLRIAKVAACSPGGGARGGLDAPDGSYGWPEPELERQNDPEELLRPAPRDVELLVEYSVILSPVYCVPVLHFSLRGASAASRADLDFAYRHVVTRGHTEQLRNPGIIGGLSMTNHPHSGEPVFFVHPCNTTAALEACAPDGGIDCFGYLCLWLGIIGGPVGLCVPPTLVVGEVSGSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYA6</accession>
    <name>A0A6A6NYA6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_372599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYA6"/>
    <dbReference type="OrthoDB" id="3942880at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="237" mass="26493" checksum="0D08DF97E97E101B" modified="2020-06-17" version="1">MSPTVAVAALGAQEWTRNHQDGQAGTNGRSALAYSSASEAASAALARVRVDCANAEHPTELRLTVFDALHALRFDSKLSFQVQRAVTKLLLEATTAADGYRFNERQTMDQKRLRGTRWRFVCRDSLHNRDRIANWKRSVTGKRSWRKEGDPRELTKGARPTYDRGGNIYMTFAGAENRIELRYRHLPIHQTNNQEQVAFTGNQNSIMVTPDAEQVQASYDASNGDDAAVKMPPTGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYM6</accession>
    <name>A0A6A6NYM6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_422379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYM6"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046536">
        <property type="entry name" value="DUF6601"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414:SF1">
        <property type="entry name" value="SUBTILISIN-LIKE SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20246">
        <property type="entry name" value="DUF6601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="140" mass="16370" checksum="C559C7DE582D4585" modified="2020-06-17" version="1">MSLLPPVAIKRELWNLKPEYPAAIRDRNQTLLLSADLTTPQLDNVRESLWLAGLPRPARPLRHQKLLNDLEITKEIRIVLKEIAWTAFVKDFLAKINPATLEDVNKRYQYGELRLSRLNNYFSRNFAWLLVLFAYISIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYN9</accession>
    <name>A0A6A6NYN9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">von Willebrand and RING finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_305417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYN9"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000014">
        <property type="entry name" value="von Willebrand and RING finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="23"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="327"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="515"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="889"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="902"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="933"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1045" mass="115052" checksum="15954F8EA28FE2FB" modified="2020-06-17" version="1">MAGVLDLDRSRTRRERTFIGVECAVCEEPLEHTLKGERILQLSCAHVCHEACFYEYIREFESQTCPSCDQSLGLDSSRGGNVLDIEKLSSFVRSVQVTEPRAVPPPGKSGQQQQQQQQQQQQQQQQRPHHQHMPSHASAPSWDRHHSAPDVRQGGGYRDSRETGHTMNEPMGTGAHGRSHARNDSGTTGGIASSADFEPHMPPSGRRHDFDVQSMETSLSSPRAILRNPIPAPTVTVRSEFPTLSRSRQQQSLTCLVTVEVVERNWRPDPEDIRVAPPLPSIDGYSRAKSPPPAHHRAFEIPYEPPEVLDELTEDLHGRVDNWHGLDFSRFGKLRLHGHVRVGKDRQSWQELECYLFSEMLICVKEKKNAQGLHWDGSESMTQRKPRCNLKGSILIKKHLKRVESNPEDAILTLSLSVAELPSFHLQFQNRSQLEIWRRALLDINTLDTRPPDFDHDNSGTDEEDYRASRNKRSSSLHSSYGAARSNVTAPTEYTNSRHGMPDARLPTSVHVPIDIVVVIPVSSSMQGLKISLLRDALKFLVTSLGERDRMGLVTFGSSGGGVPVVGMTTKAWPGWSKILESIRPVGQKSLRADVVEGANVAMDLLMQRKSSNPLSSILLISDSSTSDAESVDFVVSRAEAAKVTIHSFGLGLTHKPDTMIELSTRTKASYTYVKDWMMLRECVAGCLGALQTTSHQNVKLKLRLPEGSPAKFVKISGALQITKRATGRDAEAALGDLRFGDKRDILVQLAISPDSASPEQLPQDPWETIVSGLEALGGPLEQDDQRVSSVEEVPLIQADLTYGDILREGSLAHLPRPSLLAITMLPAVSKARNNGRPPTPPIPPHPSVVQRRMELLTSDMLTRALTLVSRGQHERAQHLLRETRTILRGLGKGSLPPLPPNSATSRPANSPIGSNGLGSGASPTNESGDMMAPPPPPPPRRTPSPPHSDGGFSPAAGIDATTMAALDTELNASLEWIDQPAVFGRDSRKAVLQAIGVISTQRGYTFRTPSESLWAERIAGVKRLAERCREWREAGDEQALMEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYS0</accession>
    <name>A0A6A6NYS0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_40321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYS0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17402" checksum="C7072C0F8A7286A4" modified="2020-06-17" version="1">MLKFLSSRCRCWHQTLARWQQAASSVHLCVRSQPLFCCRCFAVRLPALPNVDIRQARSFSGCFCVLVIFGDRCSFFPVLLLTLRLIVRLPLPSSPSLPRLVDSPARGLSTVACHVERRPRAPRLRAFARVTARACLGPHSPVPIAWVVLGTQPSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYY0</accession>
    <name>A0A6A6NYY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYY0"/>
    <dbReference type="OrthoDB" id="5428863at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="216"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="721" mass="80867" checksum="F628B86A7D54889D" modified="2020-06-17" version="1">MAKFSGAHSRTEFSTTCETLCDRCSSLDLDDVFGSASRPRRGRSVCRIGKEIETSSCSLCRLVFALRPSQDASDKDNGGPSGQGPLNDANSAYDLCTFSAFQVFGWNKRISDDLEDTILLGVVPVGWPKTEQSTLAELSSRGFIAAVSEHDIDSRFTVRRLSADAIDWDVVSSWLHYCLENHLRHCAKVPHASIKDLRLIDCLDRQIVTLSQEEQFVALSYVWGSVSAPKSTGSSHQENDLPEVPEVVEDAIEVTKNLGYRYLWVDRYCIDQRSHEMKHSQIQQMHLVYSKAQFTIVMAAGEDASYGLPGIRGKRRKEQPMGKAFGRLLVSTLPDPCADIRRSKWASRGWTFQEGLLSRRRLVFTDWQVYFECIGMNCAEVASKPLDLLHIKDKGRMQSSAIAENSRILPLKGIVSSPLAINDFITEYTTRQMTYNSDILNGMLGILQTVRGSRWLVSHLQGVPVAAPYVYPLTGNFVKIRRSLLEGFLTNLCWNPVRPSRRRKGFPSWSWTGWFGPVSFTETSAGRGVGFDIEVDLERKSGELVSWAQYEADCDSERDIFHMPLFIHVQAWTLQLRLRPFKGGKVFDGASATSFVGDFWGVSTDLSSGDEYCIPAKLTKDPSEHEKFKEKLSLELWDGIIIGSQNFNKPHARAEPRGPAVLIVEHLEGGVTERVGLLDLAAPLLHCFPEPSGFSYRKTMLESNNLSSLLANRTWRKIRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ96</accession>
    <name>A0A6A6NZ96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BAH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ96"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="50369" checksum="0F03AFD0EAD0C598" modified="2020-06-17" version="1">MGVPSPSIEETAAKAISSSTTAGDGQAKPTPSRNLAKMTGSSLTARSDGVRPGQAAPIPRPAVPSADRMPGRLLQDRFLCGLPFSTGNRGLNQSDNDSDDEIPSIDSLYPDRSPPKPPPGRVSQNSEPEVIDLTDEPDGEDEIERLRSGATGPRDVVGSTAGRFGGNEPPATEQPDPTARASASPTEMLDSQELKELRERSLNERSCASSDAHRSKRRLRGNDAPDTAIHEERPERLIATNAGVSAQKSRRPSTGPGQAALSPGAGRATFGQIIKMAIDDEEKKAVRATTPTKDVWYFSEGDYLYVKLTGEDDAQRPPIAVVTKIISGDQVNCLWAYHPSEVVNPRGIQFGENEIVLSLDHRQSLSIANLDGVVAGQKEQRGPESEILLLTPEDPDAERALSPPQQGMKSRHSSVAPREWPVLDVCRLKAYKLEGMPWGEVVRQVTDRPEEEVQAQWDLLHAAQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZA0</accession>
    <name>A0A6A6NZA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uroporphyrin-III C-methyltransferas-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_346162</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Siroheme synthase involved in methionine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uroporphyrinogen III + 2 S-adenosyl-L-methionine = precorrin-2 + 2 S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32459"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.107"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZA0"/>
    <dbReference type="OrthoDB" id="508204at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000006">
        <property type="entry name" value="Siroheme synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000504">
        <property type="entry name" value="Siroheme synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000005">
        <property type="entry name" value="Uroporphyrin-III c-methyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012066">
        <property type="entry name" value="Met1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF6">
        <property type="entry name" value="UROPORPHYRINOGEN-III C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036555">
        <property type="entry name" value="SUMT_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="2 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="15">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="14">
        <location>
            <begin position="216"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="13">
        <location>
            <begin position="273"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2456812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="545" mass="58731" checksum="D316133265E993AF" modified="2020-06-17" version="1">MAPSLLASVDSTGHVHIIVGSNPLAGARCSRSVEVGAKPKLIAPETSSLHYGLAKRVDDGEVEWLRRDFRDEDPTTLGRAEVDHVVDAVFVTLGSANPKGAKISADCRRLRIPVNVADAPGLCTFTLLSSYTDGPLQVGVTTSGKGCKLASRIRREMAASLPSDLGKAVDRLGAMRRKIWEEDHAAELSMDLEAEEDDSGQPASFNTLIRPEDVEAARNRRMRWLAQICEYWPLKRLASITDDDVDTVLRSYASSNNSGVSATTLDERRRKGRIVLAGSGPGHPDLLTAAAHKAIASADLVLADKLVPAPVLELVPRRATVYIARKFPGNADKAQEELLEMGLDGLRAGKNVIRLKQGDPYIYGRGAEEYAFFQRNGYTPIVLPGITSALSAPLFATIPPTHRGVADQVLICTGTGRKGAAPDTPEYVGTRTVVFLMALHRLSSLVDSLVTEVKRWPKNTPCAVLERASCPDQRVIRTTLEYVCAAVEEEGSRPPGLLVVGKACKVLFDGTAKWTVEDGFKGLDGLGVESDLATLKDQNIIPGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZB0</accession>
    <name>A0A6A6NZB0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">threonine synthase</fullName>
            <ecNumber evidence="4">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_372311</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="4"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZB0"/>
    <dbReference type="OrthoDB" id="5203861at2759"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01560">
        <property type="entry name" value="Thr-synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000024">
        <property type="entry name" value="Probable threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1380.10:FF:000003">
        <property type="entry name" value="THR4p Threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="95"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="576" mass="63288" checksum="771707CE56C5E332" modified="2020-06-17" version="1">MVTHTPSQRYLSTRGGSYDLSFEEVVLKGLASDGGLFIPEEIPSLPSDWVSKWLRYSFVDLAFEIFSFFISPSEIPPEDLKHLIERSYSTFRSEDVTPLVTLKQDKGLHLLELFHGPTFAFKDVALQFLGNLFEYFLVRRNEGKKGRDREHLTVIGATSGDTGSAAIYGLRGKKDVSVFIMHPHKKISPVQEAQMTTVLDPNVHNLAVDGTFDDCQDFVKALFADPEINKTHRLAAVNSINWARILAQITYYLHAYLTLIRDPSHGFASGGVVRFVVPTGNFGDVLAGYFAKSMGLPAEKLLVATNENDILHRFWVSGRYEKHPLYGAAAEGGIPADGVKSHPEGVKETLSPAMDILVSSNFERLLWFLAHEVHGADLPSAAEKRRRAGESVNAWLQQLKSSGGFAVDAPILTTAQRDFESERVSDMQTVETIELVYDTADKPPASAWSSSTPPPPTPTRTAAGSYVLDPHSAVAVCAALRSVARCEPAPATQHIALATAHPAKFARAVEMALNGKSGFKFVDVLPKEFVGLEDKTKRLSIAKKDEGWQGVRKIVIREVELELAAAERKESEAGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZF4</accession>
    <name>A0A6A6NZF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_392737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZF4"/>
    <dbReference type="OrthoDB" id="3945682at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025426935" evidence="1">
        <location>
            <begin position="21"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="21632" checksum="051CE2B99A88A780" modified="2020-06-17" version="1">MKVTAFLTAAILAISANAAATPYQDDATVLKRAADALADALAEADPQYPPYCHLPGQSCSEKEKRDAEVYKRFCHLPGQSCSKAKRSADALAEAAAEASAVAEADSEPGYPRFCHLPGQSCSKEKRDAEAEAYRRFCHLPGQSCSKVKRAAEAIAEAIPEAEAEVYKRFCHLPGQSCSKTRRAIVDLLDVTKRAETELAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZL3</accession>
    <name>A0A6A6NZL3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E3 ubiquitin ligase complex SCF subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_386001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZL3"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="7">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="6">
        <location>
            <begin position="114"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00045385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="163" mass="18563" checksum="18C57AC323A4A889" modified="2020-06-17" version="1">MSSSQMVTLTTSDNVDIQVERAVAERSILIKNLLEDLGGESGEAIPIPNVNESVMKKVLEWCEQHKKDPPATADDDSDSRKKSTDIDDWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPDEIRKTFNIQNDFTPEEEDQIRRENEWAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P031</accession>
    <name>A0A6A6P031_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_286425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P031"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="473"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="55076" checksum="E9F2FDBE5911DBC9" modified="2020-06-17" version="1" fragment="single">AIVMGDYVYIDGGEILQDDDNGDPTDEMPVQDNATISIYLGDSWTPDSITPNVMGKAEGVPILKDLVLWGEEDDSAFYMWGGQVSPLPGQPPIPNTNLWKFTVDGNGGGSWDVSNPSNAGLFQTFHRPSMGLGTSGSNAGYLLGGYLTPRSEPQLADESDFVQPIPGIISYNMTTRVWSNDSAAGYSLYGAGNLGQAVFLPSYGTDGLLAFMGGYNTGLETVRFDGTGLVSFDNITFYDPVSKTWYAQKATGDSPSPRAGFCAVAVAGQNGTHEIFVYGGRYDGTNEFLDDAYVLTIPGFNWFKIDYPSAQGRMSHSCHLVGKRQMLVIGGDDGELDTNRDHITNGLGILDMTEMAWTSGYDANAAEYESPQIVQDWYNQGGQDAVQWTSSDVEVLFASNSTGNSNNTSDASDPDSEDSGLNVGAIVGGVVGGVFGLLIVAGIIFWLVVRHRKKHNAPEKLALMGGPPPGVVYAQSPGILSELPDSSDRPPQELPPTNEVRKPRKPNDVYELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P091</accession>
    <name>A0A6A6P091_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_343766</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P091"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="47"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="335"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="20">
        <location>
            <begin position="440"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="547"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="927"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1012"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1016"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2457410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1094" mass="122712" checksum="C84935D49973A60B" modified="2020-06-17" version="1">MLRSNRCHLEGMAPAQLVAAKEESEELGGYFVVNGIEKLIRMLLVARRNFPLAISRPSFQKRGPSYSTFGIQIRSARPDQTTQTNVLHYLNDGNVTLRFSWRKQEFLVPVMMVLKALVETNDREIFEGIVGAAGSKGFEERQFVIDRVELLLRTYKAYELYGREKTRAYLGKRFKIALQLHEETPDEEAGTEFLRKIVLPHLGSSNVTEAQDTDKFRMLLFMIRKLYSLAEGECSVDNPDAVSTQEILLPGFLYGMLLKERLEEYLNNIRGALSEWSRNNNWQPFTGEQFRKEFESKILRRMNENIGQALEYFLSTGNLTSPTGLDLQQVSGFTVVAEKLNFLRFISHFRMVHRGAFFAEMKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCKIATRGVDVSTIPRLVSQLGLTNTTAVSLSESVVVQLDGRVLGFCSPKQAKIIADTLRFWKVEGTHGVPRELEIGYIPNSDRGQYPGIYMSSTPARMFRPVNYLLLDELDFVGPLEQPHMSIACVEEEITPKEHTHVEFDPTHILSILANMTPFSDFNQSPRNMYQCQMGKQSMGTPGTAIRYRTDNKTYRLQTGQTPIVRPPLHNEYGFDNFPNGMNAVVAVISYTGYDMDDAMIVNKHAHERGFAHGTIYKTKKIDLDESNRRAKTSRTITKLFGFAPGGLVRSQWREKLDDDGLPHIGSFIRQGDIIAASHSVTYNPVSRIYENRDGETQLHRYTEHEDAFVEEVRVLGAESGAEPCQAVSIKFRVPRSPVIGDKFSSRHGQKGVCSQKFPAIDMPFSESGMQPDVIINPHAFPSRMTIGMFVESLAGKAGALHGLAQDSTPFRFDEEHTAVNYFGEQLRRAGYNYYGNEPMYSGMTGEELHADIYIGLVYYQRLRHMVNDKFQVRTTGPVSALHGQPIKGRKRGGGIRVGEMERDALIAHGAAFLLQDRLMNCSDHTLAYVCRRCGSFLSVTSVVEGYSKARHGAVSGVKCRCCAKRVDTEENVLVASKRRARAQAEREKDNGNGEGSATAAAAAATEKEGWLPKSEIWEDGAGNRFTGGNDVTVVAVPGVLRYLDIELASMGIKLKFNVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Q8</accession>
    <name>A0A6A6P0Q8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_285916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Q8"/>
    <dbReference type="OrthoDB" id="5440at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="179"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="349" mass="39518" checksum="12223A68A885152D" modified="2020-06-17" version="1">MPPRLHITAESDEFDPEFIQHWKEEGFDVSYLPFTTGKEREFIEELKHLPDDLELGEAYALIAFGDAAALALDVHQKPQPHLAALVAYYPTTIRKPNASYPSQLRLLVHLAGSQPFAPVFPSYRYEDTEPGFAESDLEEFSKAAARLAWSRSLNIVRKGFKIDVELERLWDEHVARKFVDNKFRDAAATMETMVAEPYVNHIPTLTGGIGRHDLFRFYRDFFIPGNPPSMKIKLVSRTIGTDRVADEMIVSFRHTQEVPWMLPGVPPTDKTVQVALVSVVCIRGGKLYHEHIYWDQATVLVQLGLLDPKLVPESMKSKGMKQLPVAGVEAARKVLDEDSVPSNKLLPKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P115</accession>
    <name>A0A6A6P115_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P115"/>
    <dbReference type="OrthoDB" id="5336565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="249"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="480" mass="53221" checksum="5E69C73BDF1D909E" modified="2020-06-17" version="1">MPESQPSNACKRRRAEERPPPSQSRPKRHKSRPYTGGYINTPAFWDSLSKIWLTKHALRELDRRNRLLRSPRHRPRSLPTARNALAAPSENAPLPPASAADFLRNCAPGHLQDVKRFARGGGPDLSDLVGVRAACFTYGACADDAASYPEPAPLDRNMSPSRSKDKKTSIHNDANYGQKLFDGGIIPFGVECPSGNRPPLPPNWDETRRKLAQPRCSLSPSTFPEEAKVPPAMLEAMGASRNTLENTLFNNIDPMTGDIARAKPDYFYGASHYQLHPDVRNELSEYIIPLNNTLLPAVPNFFLETKGPRGLAVVAQRQVCHDGAIGARAMQSLRSYGQSEPVYDNNAYTISSTYENGHLVMYSHSVAQPNGPGTRPEYYMHRLRSFSMVDSAATFLDGATVFKNAVDLTEKHRNDAIARANERAGQTIEDEGDDEDVNDDEVEGEKDIEDPDEDTEEDADSPPIVHILTTLRCHSKSTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P178</accession>
    <name>A0A6A6P178_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_421585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P178"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF23">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="566" mass="60756" checksum="ADD314EC07026113" modified="2020-06-17" version="1">MGSAVVPACVGRETTLMAPSITEAQGGLDERVRRGSKKFSLSGRGGDKMGELESPDETSADNLLEAMGYQPELNRNRSTLQVAFMSFVLASIPYGLATTFYYPLAGGGPTNIIWGWFAVSCIIFCVAISLGEITSVYPTAGGVYYQTFMLSPPRFRRIASWICGWAYVVGNITITLAVQFGTTLFFVACINVFESEPGVGIWEAETYQVFLTFLGITLLCNAISALGNRWLPILDTFAIFWTFSGLIAIIVCVLAIAKNGRHSGDYVFTHFEANSGWVPGWSFCVGLLHAAYATSSTGMIISMCEEVRQPSTQVPKAMVGTIVLNTLAGLLFLIPLVFVLPDIQELIALPSGQPVPTIIKSAVGSSGGAFGLLIPLLGLAIICGVACTTAASRCTWAFARDGAIPGSKWWKQVNQTLDVPLNAMMLSMTVQILLGVIYFGSAAAFNAFSGVGVICLTVSYASPIAVSLLGGRKHIKTGNFDMGIFGAFANVVAIAWTLLAVPLFSMPSYIPVEASTMNYASVVFVGFVVISTAWYIIWGHKHYQGPPAQEEDIIEHRMSVSSGHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1E5</accession>
    <name>A0A6A6P1E5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_414820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1E5"/>
    <dbReference type="OrthoDB" id="5431245at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037738">
        <property type="entry name" value="Ecm13-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36826">
        <property type="entry name" value="PROTEIN ECM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36826:SF1">
        <property type="entry name" value="PROTEIN ECM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="263" mass="29844" checksum="8B77F6454F8B21A2" modified="2020-06-17" version="1">MPSNLRIQTQFEPVSAETTRARIPSQLHAQKKQKMSLSQTYFIAASARSKLGKEASRADHDLRLLVGHANLLDSLMLDLQDAERDQEAWFHETVHKAQKADKPRHVTWVDSIPEDAYEEEEDDAASDSSDSDEEDIFEEEIVVAPVQRLPSPPAPRVSTQEIEDEDEDDFYEDLEDDEEHALTRVSSSAQPPELIHEDSDSDDDSMPPSPPQPTMEYTENARQSIKSANYYNRHPALSESEQNTFVQEGFFIPERSAPLITSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2E3</accession>
    <name>A0A6A6P2E3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_215182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2E3"/>
    <dbReference type="OrthoDB" id="1708534at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050069">
        <property type="entry name" value="Urease_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33569">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33569:SF1">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Urease" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="14668" checksum="8F3183567809A698" modified="2020-06-17" version="1">MADRNRRIPTVEPIIMRPMFAAHVPATSVTWVSQASIDSGIVKSYNLRKRVEAVRNCRAIGKKDMKYNDSMPKMKVDPERYVSHDLGAYFLTFLYFYFLFFRVFVLLCVRVLRHAVVGGTICVVRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2I7</accession>
    <name>A0A6A6P2I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_344506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2I7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="7167" checksum="EF71954BE3BEA2EC" modified="2020-06-17" version="1">MWLWVLCDFVTLFLWFFLSFCLFVFMAVCFVARRFREGYVLFLFFFFCLFFIYLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2K9</accession>
    <name>A0A6A6P2K9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_303220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2K9"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15502">
        <property type="entry name" value="PHD_Phf1p_Phf2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628:SF10">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628">
        <property type="entry name" value="POLYCOMB-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="333"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="171"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="542" mass="58139" checksum="5714768F0B2449B2" modified="2020-06-17" version="1">MMRFMASASRSEPRPRTVLAAKMSDARPEYGWFTESDTTTGALEPQPISQPQPPPQRPDPAAPHTATLPPQASDFLTAFPRMEAASLPMKHAMESTLFPSANGVVTDPANTSTSHARGFAASGGGGVGGGLSFPEFSPATAEILRRVGAAKSGSSVNWQTAREQVQNMMKTSDKIAPPPPLLNHRRSRGGAAARTAAAVPNVPRAQSVTNPPGAPVPGSEVPTGGKPAEAPQPCPQDRASAPVRTSTPTQPGSASRGRGGARGRGRGRGSGGKRKREESSDTEYSVTSDVSSDFIPMPVKTKSGRNVNKPSVFIPPPFLPPGKRRKSHRRGEATACKTCQRSQSMPNNEVVVCDDCSTPYHQYCHDPPIDRDASQASEKEWLCSSCAKPTATTDGESPNKLISSADLTEEQKRRYLLSLPSVELVNLLLKACERHPDLAFFAPATGVDMEMSQRPDMSIDLFVSSSSSHNHNTNSSTHDMGGVSSHHIRNGEDDYDGYDTDPPAHYPKPGNGLFRTLPPDSEDLERLVDENTQPFSHRMHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2L8</accession>
    <name>A0A6A6P2L8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_21942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2L8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="131" mass="14712" checksum="4FCB927355C68159" modified="2020-06-17" version="1">MLSARDILVVSQSLVITCFVHVFSQETDQMTSTGQLGGLEACSLTNRTIFQSREGPNGRGRPRRININILLLALRAQCDPHVWVAATQPQPSRRHRFSATDRSSRPVPLHLLYVVTRAILRRAQLFLSALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2R5</accession>
    <name>A0A6A6P2R5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_284198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2R5"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF177">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER MCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="302"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="505" mass="54302" checksum="3C4B72367EC61F1A" modified="2020-06-17" version="1">MTGSYKGSKPGPIEPELQERIQSLSSQKTHYPPYTTSDKTLTASECTAPSALEAGSIKSEGPAEDPKDEPPVGHRLDHYTSSVPETSEGEHTYPEGGLQAWLVVFGSFCGMTTAFGLINCIGPIQAYIMTHQLESYEESTVGWIFSVYIFLTFFCGIQIGPVFDTYGPRLLLLAGSFCLCTSVLTLGVCTEYYQFMLCFGILNGIGTSLIFSPAISAVCHFFLRKRGNATGIAAAGGSVGGTIFPLMLQSLIPKVGFGWATRILGFVLAVLCVLCCTLVRSRLPPKPGSSVMPDFRIFARADMALTTAGIFFMEWGLFIPISYLTSYMLSTGATSETFSYQLIAILNAGSCFGRWLPGYVADRFGRFNLMLLAILLCAVTTLGLWLPASILSMDESNRFDTAIVVLVIVYAAAFGFASGSNISLTPVCVGQLCETQEYGRYYATAYSVVSLGTLTGLPIAGALIETCGGDYYGMAAFTGICYFVGIAAFGSVRVMKVGWNVKAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2T9</accession>
    <name>A0A6A6P2T9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_342070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2T9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025656295" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11613" checksum="E02882576C448EE8" modified="2020-06-17" version="1">MRVCWAVRLILGLTSGRDGSGTGAAGHARRNLKGTKRLLVWNGFCGAGVARGRGGRWAAREIGWLRKPNYLAATTSLDPNNLSFPAIILRSISTNVRACTDCEATPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P341</accession>
    <name>A0A6A6P341_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_284354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P341"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF64">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="227"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="47319" checksum="9C766B314915AB59" modified="2020-06-17" version="1">MSFVIAIRPRLLVSCYTSLNLLLRQPQYQAISQRNLVYVSKWRQQLIRPEHTNLLVHQISRRTIFQDVVPAFLFPPAVFVGLVFTLWFYKCCMMILFQNKIIYMPSMPPFSRQEKLLDYANTCFPVVWKEEQILSTDGTKLVLCVGQMRAEDKQPLAGGQQRIIVLYLQGNASSTPPRLPGISRVIQSATPSLKDGPRAFEFEVVALSYRGFWKSRGHASQKGIERDTEALMEWVQYTYAGRDRNMTVPVVLWGQSIGAGIAVNAAARYLSRSQPPGLRGLLQIHGMILETPFCSIRTMLTALYPQNWLPYRYLWPFLRNWWESEEAFRTIATVNKARSKFPVYVVVAGKDEVVPREQPERLMALCRELGFHSTWKEIPGALHTEVMIRADGRKALADALRGIAVTKRQETHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P389</accession>
    <name>A0A6A6P389_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_342017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P389"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="560"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="712" mass="80176" checksum="29802E6ADA904311" modified="2020-06-17" version="1">MHTKHTNSLVGDGTVARNQGQHDLKHLRLIIQVICAVLFLISLIPHPADWIAEPQMPTHKITNDGPSTDFFSFEEIPSSPDLKWYPCYPDQLLDIECARLAVPMDYDRPLNSSKIVPTVDIALAMIPGRNRSSPSTYSSTPLLINPGGPGGSGALFVAYNGQHFRQIVRDDVDIIGFDPRGIGFTTPAANCWAFPTSDHTDGDDGDGKNTDPEVASIALMRRLLYASRRGELGLVNSTEDALPKLLEHFHLESQMCEAKDSFEGKENSILRYIGTATVATDMASIADAWTRWRKNDNSDMDESLSSKREESTKIEYWGLSYGTLLGATFAAMFPERIHRMVLDGVVNADQWTTSRFLDMLVDTDAAFETFFEYCFEAGPRCAFYSSGDNVDDIVSRYERVMSKLQEQPISGVYPDWNTPWRVDWDLLHDIIFDATYLPISRFPDIANLLQALDIGDKDKLMEYWRGIAGSPVDTPVAELFCRKELPQDLHGGDAQKAIMCGDKTHPLKGDLANLESIFKVMASRSKFADVIMTFVISCADYSIPSSPISLPWSKDDYIATQQQQINTSFPLLFISNSRDPVTPLMSGLHMADKFSDAGFLELRTEGHTSFAATSACLLARVRAYFKNGTVPKLLPPQAESTTYRDHWDTCEVDEWPWRPFDRNKWVGEASPRLDIGEVDADDMMEMLNAWKELQKMTRDWELLRRKKRYFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3C9</accession>
    <name>A0A6A6P3C9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_371153</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3C9"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF30">
        <property type="entry name" value="PROLINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="62"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="416" mass="45243" checksum="A3A9BD16B95FB0C7" modified="2020-06-17" version="1">MSSSPALLSACFTVLNALLRSKSPLTNVEKNPILSAILKNTFYAQFCAGENEAEVRQTRRRLGQMGYDGVILEYALEVLEAGEKGVTEEEEMKAIEKWKKGCLDSVSMAEPGDFLGLKWSGLGPGALSLLKSAQPPTPAIASAISTVCTLASTRSVGLLPGAEESGTNPGIDAWTLSLQRSLNRNPSGKAIMYSTYQAYLKTTPATLAAHLETASREGFTLGVKLVRGAYLAGEQRRGLAWDTKEETDCCYDELAERLLRREYGGLLQPPADTGRSARAERPAFPRVDLVLATHNLASVRKAQALRARQAERGEERIPLAYAQLMGMADEVSCELLQAVKAAERERRELKEAGKGDEAVDVPRALKCSTWGSTAECLNFLLRRAAENRDAASRTADTRDAMGREIWRRTKASVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3J9</accession>
    <name>A0A6A6P3J9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_284383</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3J9"/>
    <dbReference type="OrthoDB" id="648861at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="556" mass="61075" checksum="E2C7B2E326EB193E" modified="2020-06-17" version="1">MDPKLDDNSDSSLRLAEAQEGRHIGNITSERPTSTVESTSKRLQQDIQLSQIEPPSPTNQLSNSEAPRRSLTNVRGQDGNESNTPADVERSEAPAPSVRSTVTLALYISHFLSTWNARLFEFGAVLFLASIYPDTLRPMSIYALVRSAAAIAFSPPIGRYIDRSNRLSAVRVSIVGQRFSVVVSCIILYFMETLRLTTRVKTAFLSLVIILACSEKLAFVLNTVAVERDWVVVITDGREDALRVINARMRRIDLFCKLIGPLVISFIDAASTKIAALVTLGMSLVSVFIEYFCIARVYTLVPSLHRHPTVPPAQAHLPTTSPTTPTLLRRLRALSLSLRHALPLRFYFTHRTLLPSLCLSLLYLTVLSFSAHMTAFLLSVPGWTAAVVGGARAAAAVAELSATWVAPRLMARVGPLRAGIWCAAWLMAWVGVGVGMFWGKERLVVATGGLVAGVGMSRLGLWGFDLCMQVIIQEEVEAPHRGAFSAVEAALQNLFELCSYASTIAWARPDQFRWPVLMSAVAVYLAGGLYATFLRKRRGHLVHNPMKSMGCIPREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4G3</accession>
    <name>A0A6A6P4G3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CLP1</name>
        <name evidence="14" type="ORF">BDY21DRAFT_409668</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Polynucleotide 5'-kinase involved in rRNA processing.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Clp1 family. Clp1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4G3"/>
    <dbReference type="OrthoDB" id="258143at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1030">
        <property type="entry name" value="Clp1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.330">
        <property type="entry name" value="Pre-mRNA cleavage complex subunit Clp1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03035">
        <property type="entry name" value="Clp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028606">
        <property type="entry name" value="Clp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010655">
        <property type="entry name" value="Clp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038238">
        <property type="entry name" value="Clp1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032324">
        <property type="entry name" value="Clp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038239">
        <property type="entry name" value="Clp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF6">
        <property type="entry name" value="POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06807">
        <property type="entry name" value="Clp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16573">
        <property type="entry name" value="CLP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clp1 N-terminal" evidence="12">
        <location>
            <begin position="29"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 P-loop" evidence="13">
        <location>
            <begin position="147"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 C-terminal" evidence="11">
        <location>
            <begin position="359"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="478" mass="50780" checksum="13D4DBD975CD017B" modified="2020-06-17" version="1">MSLPGLNLFAPGDSGAPTARTPAPRTDDLKPGSEFRFEVPFGSSATIKLLDTNPFSPDGSVAPTAELFGTELAPNKTYTFSGYKGAVYTWHGCRLESGGDFDGEPYVGEETPLTQHANVHFALEGLRSRAGAAAARDGFGPRVAVVGPDNAGKTSLVKTLAAYAVRAGRYPVVVNLDPRQGLLSVPGALTATVVASTLDVEDGGWGSSPISGPNPTPVKTPLVYHFGLPAPDDNARLYRPMVTRLALAATSRLEVDPEVRASGCLVDTPGVISQGKGGQYEHLSHILSEFSVNVLLVLGNERLYNDMVKRFGQSTGDDAVAVVRLPKSEGCVDRDESYMRQLRQAQVRSYFFGSRSNPLSPHGVMADFSVVTIYKIVESSSAFSFLPGTADADAAAGAVYEPVTPSLMLQNCLLAVTHADPHESEDAIRDAGVMGYVWVAAVDEAKKKLRLLMPVAGRVPNKTMLLGTWPEDVADMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4M9</accession>
    <name>A0A6A6P4M9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_370455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5416983at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1433"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="827"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="947"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="958"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1295"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1452"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1521"/>
            <end position="1531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1540" mass="162017" checksum="C897292F09E098E6" modified="2020-06-17" version="1">MAEQSHQDVVNEARSMGDPLPIDAYATSSNTASAARGKAYTENPTNATSSIATPQDVSSNPVIVAPAGKNNINGPYLAGQANSEGSAGTAKFTVAGPVQDVKTFVNGDGGIGEHLAPEDAAVQHVVAETSGGSDTDTSRAESLDRSKDRTKGSHSRSNSVKKPASFKSVSVTKNFLAKAAATSGPPPRSSDKSPQPGQPSPSPQSASRPRLVAKSGSGLGSSLQRLSKTNGNTGPDASKVWNKNQPVPPPPPKQFTDEELKLQYGIHMATRLSAEDSGKESKWADIDDDEDDWAPETVEWKDGTTSTLAAENAPPVSHDVPKKSSSPAPISREVKPALDTGRPSQPPSGQPIQRPSSTSGTAKTILKPGAAAAAASSTVQSKTSGGLVAKGGAEKATLVAKPSSSAPLKNPWAPLPPVDKISPIAPPVQQPVPQSSHAPRFTQRDHHGFDAMPPTPSPAKEINADDFNRSWRDGDRATGNKELFNSQSGRYEPVNEARRGSRHDHGFRQQPSVLQRPSHAAPAEPSPAFQTSRTSSGAEMGWGRRRTSSSVSGGSGQFGRRMSLSREMGPTMLPEPTAPMGRRESQAGLESLGPGIGGPKHAGFPPRGAVPDRVASPAQQSFTQRSSPSMSYAQPASPYRTTASPVSQQASAVGSSVADQIAIQEQMMREKREHARLEKQRRLEEEEREEAAKRERLKAKLAALGPLPEGTPTKPKVSSPSERRREFEGSRAVEGEPASSLPHQPSRPVLKSPPKPPVPTSSSEVAQYGLMKVHQPQPVKRPVILDPAASAAPAPRRPVSHESASAPTGKDRETNLAATSPPKAEVATQHAQPPRPQQPATSSPHKTPAPTSTQQPSPPKPSTDLPSPRIANLDAQRPSGLSPPQPLDRASQSWHPPPPTEPFANWASGTMAPAAKTGNVWGPPNKGRGIGNGTFDSSYGRVHPRSRPSASPSAAPSGPSPGPIGPPSQMQPPTGPSAIRRPSPPKIAEPAEFLAAVRARDAQNQQKSSSNRLIDGARADSPPSGPTPGPIGPPNKGYTVNHWINLAQSLPKKEKAQAVTHHSSFRHEPRTPTELTAVIHHSFGGNKAGNKDNEPENEKPVDAHNAAKEIEKPTSANAASSAISDGPKDASAPALTNGEKPSAGSIQPSTHATPGRSSRFFPARSTESGTIHQPTATAAASSAFDGAFSGSGSDDLSGPPPDSLMHPAFEGYENGPKVNLPKRVRVKLPPASPSATTSPQPAVRPNLRPGVQPIVSSSAWQERINNLFKPATPVATPVSAGPSEVRLPPRHNAPSVGSSTSAQSAASSSSSGTFTHGSRYRGPPYWVDDSKDLQTREIVEFILEEREFASVPVVFVPKVLSANANEPPVSHHMIHRPLSKTYAVDAGSALTFNIAKADLEASPDGSLTVVIKMPDMTESKNVKIQNANANTRDVAPHHQNNQSNHDVPNNRGGHHRARGYRGRRGGRGGFSGPSEHNKAENQSQSGGRGGSNGSPKPKIDNPPHMGGRGGFIPPHRRALMQANNGGQANNDGRGDMYHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4Z8</accession>
    <name>A0A6A6P4Z8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_384804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4Z8"/>
    <dbReference type="OrthoDB" id="5854584at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="20973" checksum="CF3D5D5BAA971CC4" modified="2020-06-17" version="1">MEITKGKTAWLGLAISSGACAAFNGVFAKLTTTKLTTSWSHAISGALGLGDSNKLVEYAIRGMFFGLNLLFNAIMWALFTRALTLATSTVRVSVINTSANFMLTALLGAAIFRESLPGLWWLGAAMLVAGSVIIGRREQAEKSGDGGTAGAEPLLGPGTEFRDDLGEDAALPCAAEPGSRADDARSSVELRTVDQDDDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5T4</accession>
    <name>A0A6A6P5T4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA mismatch repair protein mutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_301046</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5T4"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03483">
        <property type="entry name" value="MutL_Trans_MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000033">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="7">
        <location>
            <begin position="247"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="666"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2459092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="745" mass="83044" checksum="897B0395EA7F4A92" modified="2020-06-17" version="1">MKEGLSNEQGLSRGTKRKPDEDEILVQPPRRIRALAQDVVNKIAAGEIIVAPVHALKELIENSVDAGATMLEILVKEGGLKLLQITDNGHGINRDDLPVLCERFTTSKLKAFEDLTSIGTYGFRGEALASISHIAHLTVATRTKDSSCAWRASYADGKMAAPKAGQSAEPKACAGRIGTQITVEDLFYNIPNRRRAFRSASEEYAKILDLVGRYAIHCTNVAFSCKKHGDSTPGISVPEKANTLDRIRHVHGSSVANELIPLEISDDRWGFKAELWASNANYSVKKTTFLLFINHRAVESSAIKKAVDSLYSTFLPKGGHPFVYLSLEIEPQRVDVNVHPTKREVNFLNEEEIIGVITNEIRENLGKVDTSRTFMTQTLLPGAQVLRASVETPRREKLPTDAEPDPQLSKSIDRRPPASKQRPYENNLIRTDSRARKITSMLSTGQQSMSAQAATGGDTGLQELKYKYSDKEPTVCRLTSIKELRAEVRDNMHNELTDVFASHTFVGVVDERKRIAAIQSGVKLYLVDYGMICNEYFYQLGLTDFGNFGCIRFEPPLSLQEILNVAATQERTVAEAPEDFDWDEVVIVVRKQLINRRDMLAEYFSVEISEDGDLHAIPLMMKGYLPSMAKLPQFLLRLGPHVNWLEEKACFQSFLRELASFYVPESLPTPPPPASQTPGMEGDEGTVDKDSEDAEVHGRRLQLNRAIENVVFPAFKARLVSTRGLLKGVVEVANLKGLYRVFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Z2</accession>
    <name>A0A6A6P5Z2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Z2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025570205" evidence="1">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="162" mass="17198" checksum="4171BC50B1820417" modified="2020-06-17" version="1">MGHRILRAVLLISGAFLLALGAGVAGTSSDAFDAMSDLREWLAAANRTSGLFEAVPDDYREGSSTSVLILRNRPAGYASVGGNGASSLASLVALVYAMADATTNSSLDLGPETPDADKGSVNMESWTCQLKTILPVHFMRQQVESDAEVYNKQHPLKEEPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Q3</accession>
    <name>A0A6A6P6Q3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_409388</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Q3"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="474" mass="50410" checksum="F902180D3C7F0B2C" modified="2020-06-17" version="1">MEAPAGDSEPSYIDYDAFLTPDFSATQFANSLVLSMNDPSDTPLDLSTPLSRVLFDVQEIDTHIDSLTTRSALPLLEHTRADAQSSGRILKELDAQLGALNEAYATLRREVLERHEGAELVRGVAERLCETVRLGRAVGRCLMLGRQLEVQMGEFAGSGVAGPAGALGSARREDHRAMVRAANTLVLLRQLLSATGKEEEGAGLDRVNAVVTLRTELIGPAERNVLSRAQQIVREFSMSSLLAASAQSQQSSSANVSAISASTFAQAEDTRSRATSALLTLYLLSPLPSKTPASDFEPTLLLSALQDYLQTALKSSLAALSRALATLPQLDRVLLEVSARCQNIVALETLLSATKPPAHPLVDASDAALTTAPTPPNFLTPLLSALDTTSLSSWFWRSLAAALTGRVAEILARGGVSARTLRSNRERVRDAVRDAVGRGARLPASRGGPADAAARGWEREAAVMVQAIVGAMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6S7</accession>
    <name>A0A6A6P6S7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-lactamase superfamily domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_413985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6S7"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="42516" checksum="E728234B3AE60F15" modified="2020-06-17" version="1">MSLTVRALNGDTSFLLTFAPSSAPPARDGRGASSSFPGSFTILIDPWLYEAGPAKILSPRFSVASLPPVRIGSANGTTPPTAGDGRANGAGAGNARDPSVLTSLADLPPGVPDLVLISQDKPDHCHLNTLRTLPRATDALILAAPAAARKIRRMRHFAPSVRVLPLPAYDASAAVVAIDIPPPTPSSPASAPGQVTVARIRQPRDVAGVHDALAITYRAPTTVLSLRPAGEAHDHDHDLSTARPPISAPLPIAPSPSSPLSPSSSSPSPTTPHEPTLSVLYAPHGIHAALLRPYLSAHLVPRRGALPLTCLLHSFDEVRNPWWMGGAIAHGAPGGAAVVRLCGARAWLAAHDAVKRLAGLGVARTVVTRWGVQDVRRALRDGAAADAPAAGTGETEVVSLEVGEEFTVSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T1</accession>
    <name>A0A6A6P6T1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_263478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T1"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="181"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2459133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="377" mass="39392" checksum="E141DDB777251DE4" modified="2020-06-17" version="1" fragment="single">LNAHLATRTTLLGAKPSAADVAAWAAVSPVVRGWDAEARTGELGLHHVVRFVAWVQETGVFGLRGVLGEGEKVGVDRDEVVVRVKQVDVKAEKERKKKEKEGAEGAGGIKEKVGEAKEAVEGKAAAAVAKVKGKGKGKAEGEDAAAAGTTAAAAPQEGKKKEKKEKAPKPAKAPPKETPLSPHLIDLRVGHILKCELHPNADSLFVSTMAVGDPPGTDNTSEYDGHVVRTVCSGLNGLVPLNEMQGRKVVAVCNLKPVTMRGVKSCAMVLAASPRDDAEHKGPVELVKPPPGAKAGDRVCFEGWEGEPEGMLNPKKKVWETLQPGFTTTEGREVAFDAGAVEALVGAEHVGGREGNRVLKAGGEACTVETLVGATVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7A8</accession>
    <name>A0A6A6P7A8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7A8"/>
    <dbReference type="OrthoDB" id="2129069at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="32769" checksum="E31001DCBCC15642" modified="2020-06-17" version="1">MFNTNLRHRPSVANLISTVVSPPPRGLSLLESALPEHDLAVPIPNTNPQRTLRMLVLTPSSAADLPRIQRFASLTGGQDVAVVFHMDRSPTITSTASSASSVPRHPQQGSIGAAVNDGSEGEEPTQTSPLAAFHALEILLLDSALALPLIPLPRPAALPRLVSAFLRGVAQANAAGHGPRNAQQQSQANVPRGRGTGGLAIPTSAPVNAALDLLPWCSSEAPLRREHVHILSDLCPNLRSVAELAAWAGRAEGYRGRIRGEEEIGEGMSRREIERAARAWRLLSEYLGERAARGVVEFWEKETVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7F7</accession>
    <name>A0A6A6P7F7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bromodomain associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_384262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7F7"/>
    <dbReference type="OrthoDB" id="5402929at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00076">
        <property type="entry name" value="HFD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006565">
        <property type="entry name" value="BTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07524">
        <property type="entry name" value="Bromo_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00576">
        <property type="entry name" value="BTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromodomain associated" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="246" mass="27682" checksum="EEB627960A791845" modified="2020-06-17" version="1">MLHTALLRPTVLHILRAAGFHSARPSVIDVLTDIMARYLHLLAVQTAAHATHNHNDLEPTITDVRLAMADCGVFLANTAASEEAWREAFRKPLEEYPERNGIRAREMARRDAEDTADVREFIEWVKGDAHKEIRRIAGFLPTDAAQGVKMDDTRTQPEDYLTVLKKKHNKTGEESRYQGTVLGIAAESKPIKIEGGPAESLAEWNRQAFELSRKAHEKAEKNGKNDTRMETDEPHETNGDPMQAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P842</accession>
    <name>A0A6A6P842_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_185046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P842"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="173" mass="19148" checksum="6B1E81EF1ECA5C9F" modified="2020-06-17" version="1">MHVTRFASWRQSSNFYVVMRIRGRPNSFPMLHATGIAPSGSRCVSTCGRLQVRCCGVRSGALPKRVIVLSYIFSDLRLHKGTCSRRAPRPISSFPRIFLFSRQRQSGEDPCTGCGDWRHSRGTCLQLVASSPVPYYCYKSRTGLKSKSCDIRGLDSAAWILVTSGTPAARGCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Q6</accession>
    <name>A0A6A6P8Q6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_337772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Q6"/>
    <dbReference type="OrthoDB" id="3779160at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025688866" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14166" checksum="3E1B868F3178BE15" modified="2020-06-17" version="1">MSASDQFRGSICLHILVTLISTVPIIMKVECSTRAIHDLEVVHNCLMPRNMPNEDTGQVMVIDFESSMVSEPQPVPGVISAYQKRGRDSELRRLLCLAFAAVEYPFRFFGQIVHSREQASCRYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8V8</accession>
    <name>A0A6A6P8V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">6-methylsalicylate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_279903</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>6-methylsalicylate + H(+) = 3-methylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:23112"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17231"/>
            <dbReference type="ChEBI" id="CHEBI:36658"/>
            <dbReference type="EC" id="4.1.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:23113"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.52" evidence="7"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8V8"/>
    <dbReference type="OrthoDB" id="2832284at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047596">
        <property type="term" value="F:6-methylsalicylate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF29">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="4"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="361" mass="38126" checksum="8E1B43752100943C" modified="2020-06-17" version="1">MERIDTHVHCVPDVWREACLKYGHGCPDGMPAIPQWDTTTHLALMDELSITRSILSITSPGTHLKRLASSEMASLTAATNDALSAICAAHPSRFSFFASLPLPDVPASLAEIDRVFGDNPLPGVAGFCLMTNAHGAYLGDKALDPIFDALSARQAVVFMHPTTCHAAHAPLRGPSGGSADAAATAVDDGAEDAIRPLAQYPSPMLEFFFDTTRAVANLLLSGTVSRCPGITFIAPHAGAALPPLAERFGQFASVIYGAQPPGGLAGGDGVKRVLRDRFFFDLAGFPFPDQIHGLLRLVGPDRMLYGSDFPYTPRPSVVGLAERMRVGLRELFDEGMAARIECGNARALFGGSGAGAGRSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P985</accession>
    <name>A0A6A6P985_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Marvel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_335621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P985"/>
    <dbReference type="OrthoDB" id="5342507at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27318" checksum="3F5C48C53AC7D762" modified="2020-06-17" version="1">MAKFGGLFLKAVQTFLYAVEFCCAGIVLAIYSYFLSVLADRDIPIAAWKKAVEGMSGIAVVYTIFAVLLTCFLGGKTFFAFLAIVLDILFAAVFIAIAVLTRDGAGSCSGYVETPLGDGPEDADGARYNVNDNETVTVAVDLGLACRLNKAAFAVSIIAVVLFIISAAVQLALGRHHRKEKRFGPSPANNYTSGSGRRRFFWQRKNRTDPEHAGGMKNDRPSYETASTVPQHNGYHTAPTGTYGYERGTASNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9L4</accession>
    <name>A0A6A6P9L4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_167988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9L4"/>
    <dbReference type="OrthoDB" id="343070at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="252" mass="27860" checksum="073F754DB6F7115A" modified="2020-06-17" version="1">MAAAVDTAYLAASYAIPKETFDTIVDAPTVDLVRSLLDQLAAKARDFDQLKSDKLRADVELENAIRAGESRTRALKTSVDNSLKEIEELRKKLNDEENARVTVETELQNLKSSTTTSSSEKDALETRITTLEASNRDALALVESNSLHSSKRSPLSKRRTARLRTTLSASNSASSHSSRRWSFSRKTTSGSRRSLTRATPNTPNTARKRVHVFPSFNGIMRMQASGSNLSSVPKPLSVTNVPRSTRRRRKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9X0</accession>
    <name>A0A6A6P9X0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mitochondrial F1F0 ATP synthase subunit Atp18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_336168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9X0"/>
    <dbReference type="OrthoDB" id="5520611at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006995">
        <property type="entry name" value="ATP_synth_F0_jsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28060">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT J, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28060:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT J, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04911">
        <property type="entry name" value="ATP-synt_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6767" checksum="3A49AED0FCCDC4C0" modified="2020-06-17" version="1">MSGLLGKKWPVPIMKPYWPFFAAGALVAYGINSFQNVLMNTDEYKNDPRNPNARNKKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9Y9</accession>
    <name>A0A6A6P9Y9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_336152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9Y9"/>
    <dbReference type="OrthoDB" id="1421013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="9473" checksum="89217D6F8B278651" modified="2020-06-17" version="1">MPLLDRAKLFALSTYAFESVLFCKLSSRVRPFAFAVCSFLTPATALLQEHVLVVHFVYLFSSRLFSTLMEPRRSHRVFTKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAK1</accession>
    <name>A0A6A6PAK1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_418919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAK1"/>
    <dbReference type="OrthoDB" id="5365129at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="351" mass="38941" checksum="C8336AB91530B355" modified="2020-06-17" version="1">MAFVLGIIGNTISVMNLAAGFIPSSGDLDGGSRVRLGVGLDTSGGLSEAGGDVPYMRTYNANRDFIGEFFPGHREGVFGNSWMVWDEVDDGSFVDAWVRPRRDHEGQQPQYLELNMIADDEDGICLAYVTHVWPDGHTFGWIGDWGRHCGHAWYHSNIVIDDAGHKTACTWLDKNHDNHIKVNSLKLHMPSFGRDETNGGTAHSSDWYCHHPAAIQFFDRGDPLFWWVLEGRGIDGVAESQDQHEQQQPHAFSRRSESLAGRLIISNSTAHGATELCESGSSYGPDFVSLAEGQFCDMETHTLYPLCEDNSATSCFDVDSRDLRPADLGSVVARSSFVVKRAKYGKVMEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAT9</accession>
    <name>A0A6A6PAT9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore assembly and biogenesis-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_138385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAT9"/>
    <dbReference type="OrthoDB" id="3559694at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024316">
        <property type="entry name" value="APQ12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12716">
        <property type="entry name" value="Apq12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17839" checksum="393EED2F0FA19048" modified="2020-06-17" version="1">MEVILDWMHAVLPAEARSFFSPISAPIHALSCLARDRVLPVVGRTVQSPDLASVALLVVIFFISLRIVHMLYRAVVFWVSLTLRLLFWLAVAGAALYLWDRGFDGTVADAEYLVGYWWDEYRRFQMQAEEHRLREAAGFYREPVPRPQREDWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAZ3</accession>
    <name>A0A6A6PAZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_334064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAZ3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025570601" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10225" checksum="CDFB420427323FD0" modified="2020-06-17" version="1">MLLLFLFLFVFFFLFSTFVPSWRGCGGLAVCPPRAPAGPGFALRVGLGARVNTEVLRTWKGVGRVVWGKGQFPMREASRTYGGWYVCRYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB40</accession>
    <name>A0A6A6PB40_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_140058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB40"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="29946" checksum="9B27E5C260F59AE4" modified="2020-06-17" version="1">MYFARAAGGGPSPDEHPAVRRGRRGGDAGAGKERARAEDEELPDERGYDEDDDEEEWRLDAPGDSSRQWRDGGAKPLEAWGYGVPGASLSQASLTTRATEEGEDSGGELGSGSGSGSGSGSGSEWRSSVSSEATVTVRGVAGRRDANGSGSREVGEGEAMGMEREGGCESDAESEDSANVGYYTPSEFPVMLEERGDEGRREEEAGRPALRRVAHGLIQEVAASKPNSVTNDEPAPDDDDFALSGEVLRLHSKPEESMAAIQPRLFLRAANDRYYIIDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB88</accession>
    <name>A0A6A6PB88_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable transporter MCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_334668</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB88"/>
    <dbReference type="OrthoDB" id="199930at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF45">
        <property type="entry name" value="TRANSPORTER MCH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="542"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="459"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="668" mass="71784" checksum="6FFD6AF1417461C0" modified="2020-06-17" version="1">MPEPSWSGNARIDKLDFPGPDARRPLLSPDRHAGEGGSSSAGEESGGRPSNDTSYAGSFFEHVAVGIQERERKKLTRKIVRYGSFAWAIVNCLCAGSITAYSLYGHLFQSRLHYSQFQVNMVSIAAELAMYLPVPAFGYLCDRLGPAIPSMLSGAFFGVGYLLAAFSYKSGPPPSADGNGWPFAVMIVGFVGVGMGTSCMYLSGVTTCAKNFGRGKHKGLALAMPIAAFGLSGMWQSQLGSRLLYERRPDGSKGDVDVHRYFLFLGILLLAVGLIGGVALRIVDEEELIDAAVEDLARSGLLAEEARGGEEDGETQFFLRAAAHRHGYGSIVSEDGSVAAGDLSDSTREFLRSEAEEMKAHAEEERRKKNWLLNGETRRFLADHTMWWLAAGFFLVTGPGEAFINNLGTIIGTLYASERTKVGDGEVSGNQTSAATHVSIVAITSTVARLVTGTLSDLLAPPATSERPYTQPTSQPTTPAFERPQPFTHAASSVSPPPTKRRFRFQLPRISRLAFLLAFSLLLSFGQVCLATGLAQQHGERFWVVSACVGAGYGAVFSLVPIVVSVVWGVENFGTNWGIVAMMPAIGAAVWGVVYSGVYQAASGKGDDAGGEKVGMLVVKQEEDTLCYGKDCYAPTFWAMAVSVWVACGLWTWAWRGPGGWKRRGIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBC8</accession>
    <name>A0A6A6PBC8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_82014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="6">
        <location>
            <begin position="182"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="709"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="843"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="972"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1020"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1265"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1319"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="860"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1029"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1113"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1138"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1181"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1232"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1276"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1352"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1385"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1470"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1497"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1538"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1584"/>
            <end position="1595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1595" mass="176169" checksum="3272C01B5FF3A884" modified="2020-06-17" version="1">MPAQRPRASFEPLPPDFDVRALVENTDNFQYVDRISYDVIEQNGFDSFEKLVLLHAIIGGKPLVIDGFLDRLDPWTFTPGWLKSNHGKKIENARNLTAKDYLPLTIGHYLDNMSLLTDQFWHKRSHYKDKNRQRIYLKDIDCPPVWHDKLRERIPPSLFYMNDSVGDIGGPGAPIDNSTATGTRRKGRGIAKAADLMSSLPPEMRAVNLMCYVGHEGTYTPAHREMCASMGQNIMVEASGTVGEGGRPEKPGSSLWLMTESKDRHMVAEYWLSVLGHDIEVESHFAQISAWRKAPFTVYVVEQRPGDFILIPPLAPHQVWNRGTRTMKVAWNRTTVETLEMAMNEALPNARMVCRDEQYKNKAIIYYTLAKYSGLLRQASARAAQGDDTISHAPKIRQVKKDFRRLFFLFQRIMVSEMFGSDQPQDREFLPYDSNVTCAYCRGNIFNRFLTCPSCKDALGTGTDEPYDICMECYAMGRSCACISGLRWVEQWKWKDLTKKYEDWRRQIIEIDGGVSESTPLSLTDERGRQSKKTLAQICQEQLKRRPWIDIKNMKNLEDDENEDEEIVINDDGTVKKVRSKKSKEWIKKSARCHVCFHRHPKWKCANCAICDKWFCYGSLFRGHDLMPQTVMEDPNWACPHCRRVCNAGACRRDPSQHPYEPKGTLLGHDTRKVADARSVESLVDFSVSNLNWLKDNPDEQPHQNARLMKRKEAADQEKANGSMLDGNHYVDDDGVEHTSGGRTPGDNSQIVYSPGADGGAADGSVPIDPALLSEHVPPGYVPSTANGAPPGYVPGETNGLPGGDSPAPSAFVAPSAIMYNAGPAAALQDEEEDISFLYPEPHSTFDNDGELEEPATITRKTKKKKKKRGTNGADEVEDDGDFIIQTMQTRKRSNAVEDGEVAIPLHKRNDASAQFRRQQEKKHLEEAKKAGRFIAANAALRGRKKFVKLKVGVEKLQHFNEDLRRRALEQQRLQRGRQTRQEDDDEEEWNEAAGAGAVENGLDVSRLKVLLTSDVAALEKGDGPGHRGPGHGHKHKKYNNQVRVPVEEDEDFATSRKRKRPPPGETGPDGLSKKKARVRYESISISSEDEEDADKAGEADGAYIPGTRQRRASGEHRSSRRNRGDEENEYMPTELPEDWRDSFAARRREPKKDRRVTFTGGASIRSAVPCKRKPGRAKGSGRNSTGGTTSASAAAEPDIVPIHGGNDGMEGINAEHDTDSANDAPDVMHDTPPPTAPPAPNPAVVSSHIVAPTANMTRPAQLRPILSTSDMPLASTKKLTSPSPTSDLEQNEDPVSMARIASRIVSDNMRAKLDVARWADDNDEVSLPPSDDDFFDFGNRGLGGTPAMSKETGENNTRKSYERSISLSDDDSDSSSPPPPPSKAPARSRASAGRAPLTRAQLDGAADDETEPQPIFPHISPRAKGGSILSRMGRGGKKIKIVSAASKMKGAVGSSTEESEGSGRHGTATPGTESVQSTPSISEVNRGHGRPRKNSTPKISMTQVVPLSSEDEDEVHRAATDGDSGESDGFIPAKKGPPQRHFARRGRPSRGGVAGVVGPRRSGGFTVINGTVLGAGSGLTRSGNRRGRPPNRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBG2</accession>
    <name>A0A6A6PBG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VPS37 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_361115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBG2"/>
    <dbReference type="OrthoDB" id="10260857at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="8">
        <location>
            <begin position="227"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="40856" checksum="48F0A53BB91586D7" modified="2020-06-17" version="1">MSYPHQSPHPSSSSASAAYPPPPAPPSAVPPATQHQAAFSPASYDSATPPPPPPKPSAHSSGRGTPTTGGGPPLPPPPPQAQQAQYGGEQYGGGGGGGQGAAQQPTQQQWPGGTGGAERQASGVGGVAGEEATAPQIEFPEEGWLPDIVKDKSTPDLHALLSSPSLQHALVFSPTTAHPALAASLAPLTQLLSSNEALATSLSALESTLGHTRTAAQSRLLALRALERAWRAKQAEQDAALRDFSPVGLYQRLAAAVAEGDAVCRALEESFLEGGAGAGAGAGVGAGAGAEGDGVDGAGRASERETAEFVRRNREAWKGQWLRRERKERWDEGRRSRGVNLLRDFEGGIRRPITPKIHMLGTQKELKCGNETMYNAERGSYDSTKRLGKSKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBI0</accession>
    <name>A0A6A6PBI0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, subunit omega/K/RPB6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_278303</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBI0"/>
    <dbReference type="OrthoDB" id="259769at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00192">
        <property type="entry name" value="RNApol_arch_Rpo6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020708">
        <property type="entry name" value="DNA-dir_RNA_polK_14-18kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028363">
        <property type="entry name" value="RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006111">
        <property type="entry name" value="Rpo6/Rpb6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002208">
        <property type="entry name" value="PRK01099.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500154">
        <property type="entry name" value="RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000778">
        <property type="entry name" value="RpoK/RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="RPB6/omega subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01111">
        <property type="entry name" value="RNA_POL_K_14KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18144" checksum="7118A3E93695E546" modified="2020-06-17" version="1">MSDYGGDDGGEPDQVYDDAEPEVDFIDEPHSANGSPQPEGQEDPYEKRQAGEGGQTPGQNVAAAGDPSAAAARAGKNTVQGLKDKKVPNEKRTTTPYMTKYERARVLGTRALQISMNAPVLVDIEGLTDPLQIALRELQERKIPLVVRRYLPDGWYEDWTCEELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBU8</accession>
    <name>A0A6A6PBU8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_397756</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBU8"/>
    <dbReference type="OrthoDB" id="2281372at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025540058" description="LysM domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="59"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="22398" checksum="01C23C60A551CE8B" modified="2020-06-17" version="1">MMQLLHALSAVLFAGVALSLPSGEYPQLDTRQLSSDNCTEYTSVAAGSVCIHIPYDCDATYIVEGGDTCKSIGEKFGNFSLTQFYKWNPDITRSCLALRAFVPVCVSTPWYTLAPPSAVQAPAGAIVPASATPVPVMPGAAPSCAAYLLVGPGVRVDAVVTAAAISLEEFLEWNANVDPEFPTVWSDYFVCVGVEEEEEGEEGGDGEAGAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBW7</accession>
    <name>A0A6A6PBW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBW7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="6479" checksum="727204C13C28D180" modified="2020-06-17" version="1">MLIFGYLGRQTRRQTSRVRKERAERRAQGKKGGGESVGDARDGKRAMEERRQTGGADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBX9</accession>
    <name>A0A6A6PBX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_86808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBX9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17335" checksum="A3A08B3E76A6DE68" modified="2020-06-17" version="1">MAARKPCVSVGGPLPDCRRPIAAMLPNGSPSPTAPLLRRAGSRLDATRMREIVRALAKKAERSCWRGVLLAVGGEPRSAIGSCRARFVVPADRFGRLVQRAGSCEEQYLSRRSANERLRIRRTSLSPRHAFFAERRIQGAARGNLEVTSRRAAVVVCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBY9</accession>
    <name>A0A6A6PBY9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_87184</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="4"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBY9"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.870:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.9.10:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00978">
        <property type="entry name" value="FAD_G3PDH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="14">
        <location>
            <begin position="325"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2461464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="528" mass="58411" checksum="1E9F6E522789AC73" modified="2020-06-17" version="1">MIPISKWWQAPYFWAGTKFYDLLAGSENIESSYFLTKSKALEVFPMLKKTDLFGALVYYDGAHNDSRMNVSLAMTAALYGATVVNHMEVTGLEKDASGRLNGARVKDLVDEANGEKPKEFRVRAKGIINATGPFTDAIRKMDEPTVEDIVAPSSGVHVILPGYYSPANMGLIDPSTSDGRVIFFLPWQGNTIAGTTDAPTKITQNPIAGEEEINWILNEIRGYLAPDINVRRGDVLAAWSGIRPLVRDPKAKKTEGLVRNHLITTSSSGLLTCSGGKWTTYRQMAEETVDEAIKEFSLKPQRLTSPPSVSGTGISDDTGALDGSCRTQKVRLIGAHGYSRTLFINLIQHYGIDTEVAKYLTAAYGDRAWTVAALSAPTEKRFPVRGERISELYPFIDGEVRYAVRHEYAQTATDVIARRMRLAFLNAQAALEALPQVIDLMAEELNWDAKRKQREWKDTVAYLGSMGLPKAKLSLSRKDVEHGRVGKYADEEFGMYARHGKDFLFSPTSSRSWPRAALNSPLMLGLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC33</accession>
    <name>A0A6A6PC33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane emp24 domain-containing protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_383509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC33"/>
    <dbReference type="OrthoDB" id="3427at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025453430" evidence="8">
        <location>
            <begin position="24"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="33"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2461514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="227" mass="25419" checksum="A77650A0C70BD6A2" modified="2020-06-17" version="1">MVSRLRPLLSLLLVAALILPTKALYFYMDSNTPKCFFEELPKDTLVVGHYSADVYNSNSRTYAPSPDLGIYISVEETFDNDHRVVSQRGSSTGRFTFTAADSGQHRLCFTPSNAAQAGGWLSGGSPPAGAVRFTLDLVIGETSQIESTDKGKIQDIVQRVKDLNGRLQDIRREQVFQREREAEFRDQSESTNARVVRWSLIQLAVLGVTCAWQLSHLRAFFIKQKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCP7</accession>
    <name>A0A6A6PCP7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BRO1-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_333104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palA/RIM20 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCP7"/>
    <dbReference type="OrthoDB" id="64867at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09241">
        <property type="entry name" value="BRO1_ScRim20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09236">
        <property type="entry name" value="V_AnPalA_UmRIM20_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF39">
        <property type="entry name" value="PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="4"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="757"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="622"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="813" mass="91178" checksum="44060827FA2024B9" modified="2020-06-17" version="1">MSSNILHLPFRRSRSAKLSEAIKQYISSKYDQHPDMFSKDLESIDQLRSGAINALEPHPSGIKKLQSYAAQLVWIGGKFPVDIGVDFTWYPALGYNRSRPVSQNNIRFELANVLFNLSAMYSQLATSANRATAEGLKTACNYFCLAAGVLSHLKTVVIPDLRTSPPEDMDETTLESLEQLLLAQGQECFWQKAVVDKLKDVSIARLAAKVSDLYSDAGDWGVKSASISSEWIHHMSAKHHHFAAAAQYRAACDCLEKRKYGEEVARLKDSLACVTEALREQRYIGKAVLNDLNGLKNRVQEDLKRAEKDNDMIYLLPVPPKPELKTLDRSTMVSLKTPKEVSDPLSMLGDNGELGRPLFSKLVPYAVHVAASIYADRRDRLVNQTIDELEALTGSMHDVLKSLNLPGSLQALEKPLGLPGGLIAHAEEIRQQNGIDRLHRSINETDRLKENDRAVYQEGVDTLRAEAEEDDHARRKYGTDRWSRPTSNQAVPKLYAQIAEIDGYLKSAASSDGIVRAKVEENEKLIRLLSGTDQDLESYVPSSRRVQMTAAVEREAARLRACLNDISRLESRRRRKIEALRVKGKQDDVNSDLLTETARLQREYPMQSVEAVQFEALFDKRLRRYDADQAAVEEERREQEALIKHLRDVNTVFVAARRGDSSTRQREQALQSLENAFFKYKEIISNLDVGRKFYNDLAKIVGKFRDDCKNFAYQRRAEASQIETDLSTAMSGLNLQQAMSLQQQREAGEQHAVHVPAPPQQEPMMAPTPTRTNVSPTTGSMWAPEMGIRFGGPGGQTPPQGGTWDPSKGVRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCU3</accession>
    <name>A0A6A6PCU3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_329673</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCU3"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="130" mass="14849" checksum="3AADEE9555ADDCEA" modified="2020-06-17" version="1">MVRTSVLNDALKSINNAERAGKRQVLIRPSSKVIVKFLQVMQRHGYIGEFEEVDDHRNGKIVIQLNGRLNKCGVISPRYNVQLRDIENWVVKLLPSRQFGYVVLTTSAGIMDHEEARRKHAGGKILGFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDL3</accession>
    <name>A0A6A6PDL3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_6830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDL3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20659" checksum="FCF34E09A1B38AA2" modified="2020-06-17" version="1">MYACVRAKDETRRLFSRFFFPFHRCSSIGAWPNGNPHLPSLIRTGSQPFKKGRERKYHTRFIRLTGGDSFPHCKGKENRRTAALTAERREAGKVRRGELKETRTGGRRWESICAVVSPRPRAAQATPCRERRLTPSCPRSAFLFSLRRLSLLRNDARFCLPAKRSRKNKKTRSGRPATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDS7</accession>
    <name>A0A6A6PDS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ATPase expression-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_330513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDS7"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024319">
        <property type="entry name" value="ATPase_expression_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12921">
        <property type="entry name" value="ATP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2462126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="818" mass="94166" checksum="0FD294B721663FE2" modified="2020-06-17" version="1">MNTFSTRLAPGGSRLASASWQQPRRHFRTPGWICASCRAQGALETGTKQSQQRHPQRLQEHRKLYPPLLKQQRRPFVTTIDNWEVNGESTGDESILEKRRRHAVDDKPECGHSERQEDMETQGMQTENMSKEELVYGRAGDEDLFNLVPPGGSRSSTAGPSATPQETATEVELALRRNDPGLLIRAIVASPYNTDYIQAVPKATFTQMLRLLDSDKIITGYTEVYKHLSLSDAANIRVYPFVDILGDYREVVQHLVRVRMSGGHQLSLLDYKQVLKGAAAVGDLSFAQRLWDMMREFGIEWDLDCFHYMMTAAVMERADHYGPSQPCQQETRVTRFNLEQRMKQERGKEYRGYGVGQNGLKEMITDVLWTLIRDGHSPTEETYSLVMRAYAREGDIEGLKSILMRTWNIDIDAIADMADINSKPTIHRFQSSDPLYPTEVLLCAIAESLGMNNMVATALRVVDHISKTYRITPSTAVWEVLVHWTAIASSRKRGWLADYNDERGRQLPATTVERMMEILQAVPYNVKPTLNMYRLLSEAYLDYANFVGMRTVINQLSKRMFHAQYRCKITTKRLLRARSLDAACTPNTLSFGTWADEGIISATGDENHRAGNISFDALKRVHEDAHLDKVRHNMTLRQLAMEYLQQSGHPLAWWGRRFEREIPDFIKERRHILPSTVRYQTPAGVVQLHIRGAAERQYMYRARSSRKGSLAARNNAQLLRERDELLDWDEAMEKHNAEVRQRKFWDYIWFYRFAGPEEPPVERDMFDSKYDVPLFIKNRRGPKYPLPAWTLGRQICEWPDEGAATSVFRVRRSAQDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDX3</accession>
    <name>A0A6A6PDX3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDX3"/>
    <dbReference type="OrthoDB" id="3945172at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="6287" checksum="96CA994A2C623D15" modified="2020-06-17" version="1" fragment="single">QRANCRYRTKESSTEDQGHATREADTRQSAKRAKEEFPEAPDPAIGMQDERGGKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDY9</accession>
    <name>A0A6A6PDY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_277944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDY9"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="287" mass="30758" checksum="48A326EF4A4C4236" modified="2020-06-17" version="1">MTKTIHKDGNYTAISPTSPANSAAGKTIVITGGATGTGLATAHSFAVARAAVIALIARRAELLDEVSAKFKQEFPKTTFLTYAISITDPEAVEAAFADVRGKAPAGDVDVVVSSAAYFGHEEGVLGISAQKIRDTFETNVLGPLNLMRAFVGGGRGETVRGRSKVFIDVATHASWILYPASAIYGSTKGAATFVMRHLQVEHPDMRIYSFHPGFILSPAARSLGLAEDMAPWDDDNLPANFALWLASDDSDFLKGRMLWSCWDADELKEQKSAFDADEDLSTIGLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKU7</accession>
    <name>A0A6A6NKU7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_367854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001711">
        <property type="protein sequence ID" value="KAF2452331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKU7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="168" mass="19899" checksum="9CC4E920A4ECA3CA" modified="2020-06-17" version="1">MEKAKYSFNWYTTGLSECYKAFKGKTVKIRLEYPFLAQLKALNDITEVEDVDLRVKIGVLDIRRRDLGQNIIKRLNVIEIDLKYLFNPRRYKFRDIERKAMAFLWYQYFTRKRLDKISFLPWQQAKINGDGITLTDLAPTQPLALEEWPIPRALSIEYVRSIGVQSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL17</accession>
    <name>A0A6A6NL17_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_359366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL17"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="330" mass="35263" checksum="2D2A06366A033BE7" modified="2020-06-17" version="1">MPQVLGKEVGPTGFGLMGMTWRANPQPFEKSIATMRRAVELGANAWNGGEIYGTPEKNSLHLLRDYFARYPEDADKVVLCIKGATKPGQMAPDGSPENVARSINECVRLLGGAKKLDLFECARVDPGTPIETTIAAIAEHVRAGKVGGISLSEVSAATIRRAAAVHPIAAVEVEVSLFSPDIFQNGVAAACAELGIPIFAYSPMCRGFLTGEVRRPEDIPEGDVRHHMPRFQGDAFYENLKLVAGIEKIAAAKGCKPSQVALAWVRAQSGRNGNPTIIPIPGTLSIPRLEENMAHVDLTEQEIADLDQFVKNIEVVGGRYGGPGAALMNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL18</accession>
    <name>A0A6A6NL18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arca-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_294800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL18"/>
    <dbReference type="OrthoDB" id="407832at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="39553" checksum="37D3DD353E29F2A2" modified="2020-06-17" version="1" fragment="single">PLRDHREAELVIYFVNHLAPLFDICDPDKHFASVVPERAAICPALLNAVFAASAKHLSRVKNYDSLVAVAHHQECLKCIAPRLSNDIAVMDENLLAAIIILRFFEEVEVPIFEPDRQDHLLGIRALIEAQLPSMSPNEFHQAAFWVGLRQEVYMAVIHQRPIGLNLDRLTFDRSFSPAADHVWANRMVLHLANVIQYCFGDDGNIATYKQLVEYSAAWMASKPPSFIPIFVEQPEGENMFPEVLLLSDSIVVGLQYYHLARILLIAHNPKIPRLGPAQRTAIRLMDDEIKSDVRVLCGIAKSINRINPAYATACMAIGLAGDRFTSRKEQDALYNILVRTEKEYAWCTSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLQ7</accession>
    <name>A0A6A6NLQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_155836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLQ7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="11630" checksum="F59E7D2CC721F685" modified="2020-06-17" version="1">MRARLVSGNHREWARAGVLGVLVLPLLFALSLPFCTFSFFLFLPCASAGGYAARASSAGRSIGGLLIGGRAGCSSRLSQDALHDILRWQPEKGGIAEQMNKPLNGGKLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM27</accession>
    <name>A0A6A6NM27_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein transport protein SEC13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Protein transport protein sec13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_359354</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM27"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090114">
        <property type="term" value="P:COPII-coated vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032527">
        <property type="term" value="P:protein exit from endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000017">
        <property type="entry name" value="SEC13 homolog (S. cerevisiae)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="6 13" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2452394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="33257" checksum="B470BBE8A6B718FA" modified="2020-06-17" version="1">MAQTITNTGHDDMIHDAVLDYYGRRLATCSSDKTINIFEVEGETQRLTDTLKGHEGAVWCVSWAHPKYGTILASASYDGKVFIWREQAGRGWEKVYESALHSASVNLVAWAPHEAGCLLACASSDGNVSVLDFKDNAWSHNVFPAHPMGVNAVSWSPAIAPGQVAAAQGTQGGQSAPTPVRRFATGGSDCKVKIWEYNPDTKTHACLTELAAHTDWVRDVAWSPTLLAKSYVASASQDKTVRIWASTSAAGTEWTVAATLSFDAVAWRVSWSLAGNVLAVSTGDNRVSLWRERLNGEWECVKTIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMB0</accession>
    <name>A0A6A6NMB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_367489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001703">
        <property type="protein sequence ID" value="KAF2452808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMB0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="27730" checksum="CF4E33825F9FDE77" modified="2020-06-17" version="1">MVFGTAAIGEDKGRPVGRPFALPSPADIGIRFLYVPAKTGKWRTGLLAVFPDAVAAGTMASVRRPERPWAPSDGASSTESLGHCGSPWREAPLSVSPHVPVSPLRSRERVAFAVALGRVWDLRAASFSTCLLLPSYGQVLSGGMNNVAWGEKGENGQCHMEGAANHNGPAPRPSTEVQAYPTRRQLEVARPHVLQLRPSQRSAAPAGCRAPDLAPPARPFIPRTPKPDVLLPSLLPFLLRLSTPVRLSAVRLLPRLLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMJ8</accession>
    <name>A0A6A6NMJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_367383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMJ8"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000576">
        <property type="entry name" value="C2H2 transcription factor (AmdX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="494"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="960"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="970"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="997"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1018"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2452975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1267" mass="132025" checksum="3F1D4682F23FD742" modified="2020-06-17" version="1">MASDADSQGSTASTTSTETTATTTAAGKGINGANAPNPSAGNAASASPTSKDETPQGASGNFPPPKTDKPRPHVCGTCGRSFARLEHLKRHERSHTKEKPFECPQCARCFARRDLLLRHQQKLHLAGATSSRPRNGGRRESTSGMPPNGVGRVRKNSIASSTASTSAGTGMRPRANTISHIDAGALGGLFGAGAGMGRANGMGGHGHHPTFGGLHGPGAFDYRGMSNSLGNHGNPQALPKLDTHLGMGLGGGLHTAPVPNGFGDPYDLDKFLGGGSTINPAQLHFGGSLGTPTSPFQAFPPFTGIPTMDEEDQFDLSAGIDQQMMLNGVNENAIDGSSPSAISSASQSGFSEIMIDGSNQPGQVSGAMWQNPMVTSSSMPPPSTFGLDPAMFPDMLTSLNTVSPKDLHEQSANNDLYLSSPPPLSIGSTAIPGMPTQYFNPPMNFHSDGTSVGSSSIAGSARQSSVTSVSTASITETTRQALLATLSQPSAFGHRKYSPQAAGSPLSPGFGASSGAGQNTSLPSTADLQRYVSSYIQYFHPHLPFLHLPTLSFDSPVYTNHMRTASHAPHAFGAHDGVVGGGGCLILAMAAIGALYEYEYQAGKDLFEATKKVLQLYLEERRKAGLSAVNGANVTDLSVQKTPLWLVQAMLLNLVYGYNCGDKVAAENASTHCAALVGLAKDVATGPGMHDRTNGVGVGVGVGDGDVEMTDGMPDALGEHKDWLSWKDEEERKRTMFAVFIISSLTVSAYNHSPRILNSELFCDLPCEENLWSAETAQAWSGIGGRAAANQTRVSFADALGWLLAANQRQQTEQHDTSFHQSSFGSVGGGEPMDDGNMAPPAESELRTSTFGCYILINALHVYIWETRQRHSGRAWKTEETDALHAQIEPALRAWQAAWKANPHHTLERPNPFGPLAADSIPLLDLAYVRLFVNLGRAKDALWARDYDRMADELARGSEVVQHASGSPDSQQAAVAAAASSGIPADQQSYGADLARTASSASGTSPPGGIAGPGVADASASSPVQHQQAPQPVHQDPSMAAANAAAATAAAAGGMPPPPPTTGHTSKRERLLRRAAFYAADSLLMSDSLGTTFADPGARELPMQACLCTIDCSQVLAEWVATVQERVGRYLGGVLGRDDIDLNMPPAIVMLADEDRALLEKIAEILEHAQVKLAVFGNGPGEQHAAGAGGAGAGVGVGAGAGAGAGTSGVGAQMAGCGFGSKLLMLTAYQLEKAAVWPVSHVKARALEAHAAHMNRRAEASVSVPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NML2</accession>
    <name>A0A6A6NML2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">UEV domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_367343</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NML2"/>
    <dbReference type="OrthoDB" id="306304at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072666">
        <property type="term" value="P:establishment of protein localization to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51312">
        <property type="entry name" value="SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UEV" evidence="11">
        <location>
            <begin position="7"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="SB" evidence="10">
        <location>
            <begin position="486"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="404"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="554" mass="60282" checksum="70D2C60FADC2DA7B" modified="2020-06-17" version="1">MSAVPDRVLNWLYSALINEYRDVNRTYSDVAETLSHFPSLKPRTEVFTYDNGTSALLLLLAGTVPVMFRGTVYRFPLAVWVPHAYPHESPIVFVTPTQDMLVRPGQHVAADGRVYHPYLAQWAKYWDKSSVLDFLAVLRGVFSKEPPVRSAQQGYSPPQPAPQPPPVPPPPEEWRRSQLPSQETSPSPAQVRQPPQPPQPPPKPPKPHEATASPGPQQEPQQPSVPLPPPLPPLPPDAAARYANTHGSGNQPLQPQFHAHPGDFGGQHGAAPIPPHPSATHQVQPPLEARNRGFDFPQGVPIGTGYVGAGAAPQPRPGPPPPPPEQSQVPQFSYSQQFQTYPPPYQPPPSTLQPPRESIPDLLSSPLDVTLPSQDPANAPPPAPPIPPNPEKDALLKAISQSLINQLRKAVEEHAAALPALNAQNAALRQAHARLEGEMRALRALDEDLASNERALHQSIHSADRVIAEAARMERPDVDAVLVAPTVVASQLYSLVAEERAAAETAFVLAKALDRGRLSCDVFVRQTRAIHRDAFLKKALIKKIARGIGLEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN40</accession>
    <name>A0A6A6NN40_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_424709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN40"/>
    <dbReference type="OrthoDB" id="5132737at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470:SF2">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42470">
        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="234"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="60051" checksum="23E74C5652EE81F7" modified="2020-06-17" version="1">MARHRNPLATPKGRQQSSVQIDQGKRPRGVSEAKGRRPLRRSARLKSERSEDAERQHFLPAEKTAQEEVRLAPPRSNGRKRAREIESPVGDIPPAPVEKRRRVSPADSTAKGRTDRESSVCGIEAPINPIDYWRREKVWPKEYFEPANTMSYLLAKRKSAPSLRRKRSESGALSASSTTPSDQKPREEKSAPYQDPRYSTLLETKGSYMDKSEVGITDATSRVFLDSLFHDDVFDKACRNLKDKNEARVIQDIARLIVPSAETAAVFGAKALEVLVESVNEGWNNSIPLLGSRLQPDYAVGFKRAAFTEDQLAKIKPILGDIIDMSFFMATYYMYFPFLMCEVKCGAAALDVADRQNAHSMTLAFRAVAELFRLVRREKEIDREILGFSVSHDHHSVAIYGHYPVYDGKGFTYYRHPIRSFNFTELDGKDKWTAYKFTKNVYDVWMPDHLDRIRSAINDVPSDFDFGLSQIPESGLSQKLESHRLVQSFTEPESPALARGSQSGVVDQGTTPDTSLMEREASKRPRREAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNF2</accession>
    <name>A0A6A6NNF2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exosome component EXOSC1/CSL4-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_403909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNF2"/>
    <dbReference type="OrthoDB" id="440760at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019495">
        <property type="entry name" value="EXOSC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10447">
        <property type="entry name" value="EXOSC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="6">
        <location>
            <begin position="3"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Exosome complex component CSL4 C-terminal" evidence="5">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Exosome complex component CSL4 C-terminal" evidence="5">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21028" checksum="A23B613144694169" modified="2020-06-17" version="1">MAIALPGQRLGTTATHLSGPGTHTDPSGAIIASLAGPIQTTTAGGRGANTSSIADKPTLSIPHPPPNPTAHNGASTTVLPRVGDEVLARVTRLQARQATVEMGVGGDDSGGAFVGIVRAQDVRATEKDKVKVGECFRVGDVIRAVVISLGDQTGYYLSTATNHLGVVMATSEDGNQMYPISWKEFRDPKTGRTESRKVAKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNH7</accession>
    <name>A0A6A6NNH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_388275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNH7"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="469"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="688" mass="77637" checksum="63B9ABF649070E03" modified="2020-06-17" version="1">MAHATVVPGYCHSPPDIIHLAKLFQDMIAAIDSLGKKNASKNIHSTGASPTKDGSDSKGAEVDHIRVRASKLEYKQVDERQKAGGYRVSDSSLTAEVSELGEYVFVVRRRTDYKTQEMTCYIDIKSIQLRNVLKVVLENVRGICVKENQPSVEQNILFNFVPELRSHRLSLETSSNETQRKHLDLLLEHLDTDTAITREKFDKLVQDGDITYNILWALFTPNSEVFARCPGTEQPRCVRVNYGACRTDWIKGKIFKIECRYYDFDGFTFGEAKLELKIDEFQGTKPISQLEAFPLRFHDHPAKIRARLIECGRTFASLAVSHHREYSGVAFDKNEQDKIRKVQVNGRIILDAVAFKRMNPNYQRSKLASQLHVGENSSPTPTTNRTDPSRLHEDKLLICHVTVPGFSLRCKRWLEFAVADVRDIKWELTAIGHLTIPPKRKKIVTSLVGAHLAPKSDKAFDDVVAGKGKGINILLRGPPGVGKTLTAEIIAEHFRKPLYAVSAGELGNDSSVLETQLSKIFDTAIYWKAIVLIDEADVYVERRRIGEVQRNSIVSVFLRILEYHGGILFLTTNRVTEIDEAFATRIHMPLRYGPLSQRARRKVWVNCLEKARSTAKVAGFPQENLDELSRKELNGREIKNIVSTTQAIALDDKEKLSMSHLETVMSANAEFQSDFNGAGQTENLNSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPG7</accession>
    <name>A0A6A6NPG7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPG7"/>
    <dbReference type="OrthoDB" id="2098203at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042831">
        <property type="entry name" value="Ribosomal_mL40_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39150:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="145" mass="17285" checksum="C531398995E7F1F3" modified="2020-06-17" version="1">MLKRKGGKMQRDPRVRAIRYHLWHSKAMRPLRFSRMRGLRHWTIARAYALFKHRRRQALERDLERQYTAMRAAVEALRLMDERGVVARTEAERAAQQGAGVGRLYRIAMGKQGVWDQVPIEYARVQTEFPAKEPFNEGWRRPRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ08</accession>
    <name>A0A6A6NQ08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_292320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ08"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="33051" checksum="87399B3DAD454B7E" modified="2020-06-17" version="1">MAAEQRKLLEQLMGEQLMSGPGTSRGPQLSMTDSKVCRSYLVGTCPHDLFTNTKQDFGPCPKVHSEPLKSEYEEANNEQKKRWGFEYDYMRDMQKYVDECNRRIETAQRRLEKTPDEIRQTNILLKQISDLSENINIGLEEVRALGKSGAVSLAVMDYFKIRQYKQAKEERERELKALSDTSGPSGHQKLQVCDVCGAYLSRLDNDRRLADHFYGKMHLGYAQMRKTYEQLAKEYKGKPPPHRPETTEPQGPRGDIDGGAGDRVPYGRRGPGGYGGRGYRGGRSGGYVGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ99</accession>
    <name>A0A6A6NQ99_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL33m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_354991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ99"/>
    <dbReference type="OrthoDB" id="275534at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="entry name" value="Ribosomal protein L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052008">
        <property type="entry name" value="Mitoribosomal_protein_bL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="Ribosomal_bL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47037">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47037:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL33M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="6346" checksum="6E8C61FD4D8842C0" modified="2020-06-17" version="1">MLTCYYDRVSTAKSRTVAVRLISMAMTGYYKTFTRPRAHKPLSMLKYDPVGTSHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQH3</accession>
    <name>A0A6A6NQH3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_326600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQH3"/>
    <dbReference type="OrthoDB" id="276721at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="294" mass="31075" checksum="B17B953890B8CDD4" modified="2020-06-17" version="1">MTAASKKLVVCGGTGFLGSRICRAGASRGWDVTSLSRSGNPNWSAITSSSTAPSWSIKVDWAKGDMMDPNSYSHHLTGATAVIHSMGILLEADYKGVVQGRESPISGLRRAFSANKKGAATNPLDKDVGQGFPRLRPGEPDAQLTYELMNRDTALALALASSKARVKTFGYVSAVGGAPILPHRYITTKREAEALIAERFPDMRAVFFRPPFLYDNSRAFTLPMAAGAGVAAGINGLLGGIFTSIGGAAVAKPLKADVVADAVVEALEEEGVKGPVEPAEIERLAEKAWRRGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQH6</accession>
    <name>A0A6A6NQH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_120740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQH6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="8542" checksum="835CFC651211158F" modified="2020-06-17" version="1">MKTVMLTSSSALSGPRRRALHPGLLLVLHGSATFCLPCVVGRDTAASQDEAKPQPAHRSIAGAYVVRDSWNRSPVTWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQN8</accession>
    <name>A0A6A6NQN8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_110332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQN8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="20486" checksum="D0E72EAB3E0C4A85" modified="2020-06-17" version="1">MDLEVPARSAGISHHQVAVGHEASSARCCWADFASIALETASLVRYIRRFMRRMYSRTAPDIGRARDEFRQPRSRPIAVVDKRGALLVAWDHVLLKIQLQSSAAITEPSAVCPARSSLDAVVAAFRLSPKTCRLQNDDRDRKIATGISLVEGVGGVQGEAIPWALLDPFSSRAGHCNVLSECCPCKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRI9</accession>
    <name>A0A6A6NRI9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Catalase</fullName>
            <ecNumber evidence="3 10">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_416897</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10"/>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRI9"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000003">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF3">
        <property type="entry name" value="CATALASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025423813" description="Catalase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase core" evidence="14">
        <location>
            <begin position="53"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2454044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="727" mass="78408" checksum="A7A2A2983BE5CE83" modified="2020-06-17" version="1">MALTKLVFVLGLLAGSAASAACPFMEGALSGGVPDGEFLLDDYVVDDAGRLMTSDWGSPIADQSSLRAGERGPTLLEDFVFRNKIQRFDHERVPERVVHARGSGAHGEFVSYGDWSNITAADFLGAEGKTTPMFVRFSTVAGPRGSADTARDVHGFAAKFYTQEGNFDIVGNNIPVFFIQDAIRFPDLIHSVKMEPDSEIPTAATGHNTAWDFFSQQPSALHTLFWAMSPHGTPRGYRFMDGFGVHTFRFVNNEGQSKLVKFHWKSLQGKASLFGDEATIVSGTNADFHRQDLFDAIANGFFPEWELGVQIMEESDELRFGFDLFDPTKLVPEELVPVTPLGKMTLNRNPINFFAETEQVAFQPGHVVRGIDFTEDPLLQGRLFSYMDTALSRNGGPNFEQLPINRPVVSVNNNNRDGFGQMFIPLNAGAYTPQALNPDANPVQADESPGIGKGFLTAPSRRTGTTLIRADSPTFADVWSQPRLFFNSLLPAEQQSLVDGMRSDLSGVTSHVVRTNAVVQLNRVSHELAARVGAAFGIEPPAPEPQFYHDNRTDFVSVFNRPLARLDFLKVALLTSTSSAGSSNGTGDAAATASALKDALVADGVQLIVVAEDLFGGADMPYLAADATKFDAVVVAPGAEHLVAADAAPSALFPAGRPRDVLQKAFHFGKTVGAVGSARAALGEVGIEEGRAGVVVGDVVDGGFVEGVKEGLRTFKHLDRFEIDPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRJ0</accession>
    <name>A0A6A6NRJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Maleylacetate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_387692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRJ0"/>
    <dbReference type="OrthoDB" id="3360544at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018506">
        <property type="term" value="F:maleylacetate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08177">
        <property type="entry name" value="MAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034786">
        <property type="entry name" value="MAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF105">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="171"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="365" mass="38273" checksum="D5DF3CA84885AA07" modified="2020-06-17" version="1">MSSFEYNGNPSRVIFGSGSIQKLPAELARQKLSSPIIVSTPEQTSHAELVRDILSKAKDGPVAAAGIYSKAAMHTPAHVTEDAVAFSKKSGADSVVSIGGGSTTGLGKAISFLSGIPHVVIPTTYAGSEVTPVLGETKDGKKTTKSDPKILPGTVIYDVDLTMSLPPGLSATSGVNAIAHAVETLYSRTTSPITNLFAIEGISALANSLPIITSTDASDVPARTAAQYGAWLCGVCLGTVGMALHHKLCHALGGSFNMPHAETHTVVLPHALAYNVAAMPDDLKARLAGALPGSDGDPVKGLNVLLTRLGVKRGLKEFGLREEDVDRAAEIATSNPYWNPRPVEREKIRELIRRAWAGEEARADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRK5</accession>
    <name>A0A6A6NRK5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_111385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRK5"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="329" mass="37782" checksum="3C7EE05DA8D32407" modified="2020-06-17" version="1">MAADNEGIVIPVAPDDSELDSAYGDDALSDTTSITSSILAHRYEHGRRYHKFREGEYWGPNDEIQNDQLDLAHHMMRILLDDKLYLAPISKVKRVLDVGTGTGIWAIDFADENPDTEVIGVDLSPIQPEFVPPNCKFEVDDCCSPWTFPENHFDFIHVRCMFGSVSDWPKLYEEIYNHLEPGGWLNQMEMTIEFKSDDDTLGPDHLMVKWSELFIEAGEKFGKTFKIADRCKEWVKEAGFQDVAYYRYKLPVGPWSSDPKMKELGRWNYLHCLQGAEGWALFLLTHVMGWRVEEVMALVAKFKSELKNKKNHAYFEIAVVYGRKPSSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ1</accession>
    <name>A0A6A6NRQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_112651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="20642" checksum="1F913F4192A02890" modified="2020-06-17" version="1">MGSRSTSEHQLVKSTHRHARAKGSTEVGTMSVWISVEEFPKVRARSVDPESYFESFIEFVGRAGAASCLTLSRKETPHAVPPLQRWALAGASVCNQRQSRRQFSFLSPSSCTRIQLSKGIITAYSLINWKSASATSPHNFPTRKPNAALAYMFLHVSKAAALIQDASQLMESVTNCSGTFPIHFSPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRQ8</accession>
    <name>A0A6A6NRQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_423983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRQ8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="21517" checksum="A4B4B3633F7365F8" modified="2020-06-17" version="1">MAEFNWAPYTVGKRTGPPSRFDLNSPVMIFTMQNGCYVGQFVTPVWGYQLVYLDGQPVENGMWYLDRQVEPYILQPGPPDVAMLLSLVDSLKADIPGAPAIMVDLFRATLNAILFEALAIRESLMKALRNLLRLLFHHHPKAAPAIALLNILPLLGMFLGMTALLRSIFGGPAHKLTSAQIFVASTTPSPRRVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRV3</accession>
    <name>A0A6A6NRV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_353092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRV3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="58" mass="6594" checksum="E4DC432ED8AE116D" modified="2020-06-17" version="1">MLGWRKVSWRFHGDGGNVFLEASSGLIPAEYDYGDNWKYRECHVFSCEANIDTGIGHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSF9</accession>
    <name>A0A6A6NSF9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSF9"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="413" mass="45127" checksum="CFF0B61EA184CD87" modified="2020-06-17" version="1">MQVHAVPESERAFDPSSGRQLPWGYQYADSDLNQRPAPEEKGPFGKSRRRNISRSKTVTPARKEDQARLDNIRAVDDIFTALKTDARAQEKSRERSTGLQNTAHTLQQAAGSATTGQISKANEPTEVMLYGFGSDVQYAAIDYYERVSGGIIYEDYDRHPPHSKYNSTLSLSRLANQGSLSQAALRKKNQYVGGDHWIKITFDSAEAADRACHYSPRAIHGYTVYAERYRGVGPNADVAIPASQRGLPSQTASPSHQSSSTLPATTTLSPSSDTASSATAAGAPQHGAAGDGQLRNRQNTAAAPQGNEPAAAGARGEEERREARPLRIAGAKRAVLLPAEEALLPVGSRWQRTLGNWPVLSWLFGSGRDIIGNQVPRKEDGQFDWDNASFYWQFWAWIDSVLGTNICGLKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSJ5</accession>
    <name>A0A6A6NSJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RPEL repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_387637</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSJ5"/>
    <dbReference type="OrthoDB" id="197676at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043451">
        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004018">
        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02755">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00707">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51073">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16426" checksum="FE8114F24FF509A0" modified="2020-06-17" version="1">MSAEPAAKPVDETPISPVRSPERRNSLEKHLQHRPEAQDLKNRHILMDTNAAPSLQQAQHDLERQRATDSLKKGLAHRPDRETLIERNILPDSSAAPALQGHQKELERHMRADSLEKHLQNRPRPEELVKEGILEADENPMKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSL9</accession>
    <name>A0A6A6NSL9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSL9"/>
    <dbReference type="OrthoDB" id="5424692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="735" mass="79165" checksum="D2D136F15B2D87BD" modified="2020-06-17" version="1">MDRDRRPYDRDRYGGGESYRPGRSPPPARDSFRTRSPPPRRGPPPPAADTYVPSSSSARGGGRARSRSPPGGSSYRRRSRSPPPRGSSYRDNGPVGSGSAGGTSWRGSGRPASPPPISRRGYSPRDSRARSPIGGRDSTRYSDRSPLPHKRSRDVSPTGAAREFRDAPLPHPAGPRGSNSVASGSRYDQAPPSRSRAARYDLQEACVRCPPKLTAATIHSPPPRRAYSPPMRDSRRSPPPLSSRGAYRPRSRSPMSRRGDSYMQDEWRRRSPSPPLRSSGRDRDRDRDRDRDRERERDRDRDRERERDYYYHASGDNSGRESGATSRRSSPRVHPSRASLVPLDDRDFRTDLRERDRATRSPLDRRDLDRTPPPSRHAPRSPLPPPGPPRENSAAPPLPSGPRSRDKGGDQGPYRNGNEREREPPTSGHGPFSRAPPTGPAHRPQFVPPLATTPPAGPSRGGGGFSNPILSAPSRPRGAGPGGPSLGPGPGPGVPPGPSREYSGGGGYGSSGPGRRGGGPPFPPGRGGAPFGGAGRGAPVDVYRGSGSPPFHHGGHGHHPPQHHHYGPPFRGSANSTSTTYPRTQRFSHSGPGTGNGPSPTALAGPAPLSSNAAASAQRYLSDLPSLSSTGTRPPPAPSSSFAVQHQARIDRLEEESRRLRETIAEKQARKRAAVRDWMRAERESKAAGVRAELAEEGLRAWEEGVGGLCLVSFNIAFTGSGYFCLSYSCISLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT33</accession>
    <name>A0A6A6NT33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT33"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="282" mass="30929" checksum="86747B7360C48826" modified="2020-06-17" version="1">MTDRRKVLRHFGPVHFSGTNPKRRRFLDKWLAGRKAGGRADARLGDAARPRADEIPTSAAFAPRPAHGVHARGVRKRVMYVAEGLPAQVGDFATYDARARRRRRRRRAPRKSQDPARTKRSKASRSTRGRAGRPKAAAFSVVSGSYIPTTGAEHARERGANGDALGTRFRDRRVVPRLGFQTARAAAAPHRRPGSERAEAHAVLHAYHARSSVARQAAGCRRAAKKARCRRLNWRAWVVCTTGGERCMPAGEREKAGAELSDLSLKWPGAAVGRQATGDTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTH5</accession>
    <name>A0A6A6NTH5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_77699</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTH5"/>
    <dbReference type="OrthoDB" id="44736at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="553" mass="60510" checksum="413B82506329FC73" modified="2020-06-17" version="1">MASGGEASSYYNAGSQQPNYQYQQSQPNYGQYPPPQHGGDDPAKYGQEPPQYDHQGYGPYGYQPEGEKHSFDETFRIEKPKWNDLWAGILVSLGDGYEIGEITGGIRNLIIVFAGYVVVSGIAIQGYASTKGFNGGGIYDGSNTFSLDTNTLVLFVFVLVVSFVLSYAYVWLARLFPKAFIWVTGILNIIFGFATAIYMLSRKYYSGGIVFLLFAIFTLICFITWIKRIPFSALMLRTAVDVSKSYGHVYLVSLAGGIVAIAFGAWYSVTLVAIYVKYQPAADNPACSEGVGGCSQAKVIGLIVFVTFAMYWISEWIKNTIHTTIAGVYGSWYFCSANPPKGATRGALKRATTYSFGSISLGSLIVAIINMLRQVCSVAQRAEAAEGNIVGTILFCVLGCIIGILDWAVQFLNRYAFCHIALYGKSYVAAAKDTWRMIKDRGIDALINELLIGPVLSMGAVFVAFACALMAYCYLIFTSPAYNSDGDYTPVVVAFAFLIGLQVCNIFTTPISSGIETIFVASAWDPEVLVRDHPDLYARMVSVYPRVQTAIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTH9</accession>
    <name>A0A6A6NTH9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_387177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTH9"/>
    <dbReference type="OrthoDB" id="9981546at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="7"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="375" mass="41063" checksum="EDB5FE4CBFA12EAC" modified="2020-06-17" version="1">MTVQSHPSHLYSLPNELLLHILSYLTTLELLSLAPVSCRAHALVVRLIHARLRAAANPPEHTLLLECFPPSAKLAAPPFYCTYLSTKGLDVGIDGQDVSGGETCAEGEAGAKADVGQLGQLYGLYSRFRPLRTLPERVARRHPAGDVPGSRTFEAAAQQVAQASGSGNSSSDEAGPSGGDNSDSSDTGGGGMPRSIEGRLIDRGPVTQFLALDSHELFTQICTIANLVKLGPRRGLFNQFVEVEEGVVRVWKDWLRRVADGTTRMRAATGGSGPRDEGKGKGREREKENGVDVEFDEERTLWVRTKKNVGLRFNVRERRYWREAPLLIHADEDMPVSYDVEYEELLVRTAHLLLMVERSSTQLDLSGKAVVFGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTN0</accession>
    <name>A0A6A6NTN0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_351270</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasmic vesicle</location>
            <location evidence="1 13">COPI-coated vesicle membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="13">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTN0"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000016">
        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000001">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <keyword evidence="5 14" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="180"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="319"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="17">
        <location>
            <begin position="595"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="785"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="798"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="824"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2455125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="845" mass="93795" checksum="64E179DC4FBC5945" modified="2020-06-17" version="1">MRLDVKRQLFARSERVKGIDFHPTEPWILTTLYSGHVYIWSYETQAIVKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRVYNYNTSEKITSFEAHPDYIRAIVVHPTQPFVLTASDDMTIKLWDWDRGWKCVQTFEGHSHYVMGLAINPKDTNTFASACLDRTVKIWSLGSSTPNFTLEAHETKGVNHVDYYPQSDKPYLLTTSDDRTVKVWDYTTKAQIATLEGHTSNVSFACYHPELPVIISGSEDGTVKIWHANTYRLEQSLNYGLERAWCVSYQRGRQGIAIGFDDGAVVVKMGREEPAVSMDGSGKVIWARHTDILTAVIKGVDKSLKDGDTLTLPTKDLGSTEIYPQSLLHSPNGRFVAVCGDGEYIIYTALALRNQAFGSALDFAWGSKDNDKDYAIRESSTSVKVFRNFKEKGAGGLNVGFQAEGLSGGVLLGVKGQGGIGLFDWETGQLVRRIEVEPKSVYWSESGELVTLACEDTFYVLRFSRDSYVAALQAGEVDDDGVEAAFEVITDINESVRTGQWVGDCFVYTNATNRLNYLVGDQTYTISHFDQPMYVLGYLPRDGRIYVADKDVNVVAYALSLSVIEYQTLVLRGDLDSANEMLPEVPADQKNKIARFLEGQGYKEEALQVATDPEHRFDLALQLGKLDVALQLAEQADVEHKWKTVGDAALAAWDVALAQQCFARAKDTGSLLLLHSAGADADGLRALAAQAEAAQHHNVVFDCCWLLGDIDSCIDVLERTGRTAEAVLFAQTYKPSRAREVALDWKKALEKEGKTKVSKMLGVPPGTGDEGEAQGDADMFPEWEEYLKIEAEGGPADEEEGEDEEEQTVEADGKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTN8</accession>
    <name>A0A6A6NTN8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">catechol O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_290609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTN8"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836:SF2">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0128">Catecholamine metabolism</keyword>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="289" mass="31779" checksum="86D4EBEC15C2A0CA" modified="2020-06-17" version="1">MATFDKSKAYQDQDQVFFDDGREVELLHFVFGRPDIDSIRGNPTAVVKAIDEYGRTKKYLMNVGEDKGAIVSNLIAEVKPRIMVELGGYVGYSAILFGAAVRKANPQGKYYSLERNPEFAAVSGALVNLAGLSDTVKIEVGSSDASLKRLYEAGAFGDQIDLMFLDHWKPAYTTDLKLCEELRLVRPGSVLAADNVIKPGNPPYLEYVRSSVGEKRKAVAEQKKNGSGVDERFSSKQATMYEKRVGKVELANLVGNPNLIYESKLIESFEPSGVADGVEITRCMGEESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTW7</accession>
    <name>A0A6A6NTW7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_387030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTW7"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052909">
        <property type="term" value="F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 9 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="12">
        <location>
            <begin position="52"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="273"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="275"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="429" mass="46972" checksum="2B490D984EE8D5A3" modified="2020-06-17" version="1">MPKAATSKPARAARAGGPPYDAAAKAKKGRAANAIFKMNTGIGQHVLKNPGIAQAIVDKADLKQSDVVLEVGPGTGNLTVRILERAKRCVAVEADPRMAAEVTKRVQGRPEARRLDVLVGDVVRTDLPRFDVCVANTPYQISSPLVFKLLAARPPPRACVLMFQREFAMRLVARPGDRLYGRLSANAQMWARVDHVMKVGRNNFNPPPRVESSVVRLVPKVPRPQVSYDEWDGLLRVCFVRPNKTLRANFFGTKVVMAMLEANYRTWCAQNDVPLGDDGDDGDDGDDGDDGDDGDDGDDGDDGDDGDDGDDGDDGDDGDDGPADADAMDVEEDAAGGVDEEAWDGIRDADEGEDLPDFFKEEMARRASRPGERAPARKRKGRIHELVREKARRVLEDETGLADKRSQKCDEGDFLKLLYEFNKEGIHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTZ5</accession>
    <name>A0A6A6NTZ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_423015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTZ5"/>
    <dbReference type="OrthoDB" id="3914029at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="264" mass="26816" checksum="FF07959BD667A455" modified="2020-06-17" version="1">MDPSDNNNDTTTTDADDLPSYADSQKASSRAPAPSAPARPGQQSLVDSLTLSRAQHVRSVFAAHIWPLLSRQASLGLSGTTIALLPSDVLSSPSASPAAARSRDPIFSADEKPSSSLDDDPPPTVVEVQGLDGADADAAPLHQAQLRGAMDSAAFWGQPGVAAQLEREICERLGASSPSASPSAAAAGAPAAAPEPKRGFFGRKKGGAGTGAGAGDGYSGGVAVRPGVSVSVALEDVCLRTVSSFGLFDTSTKEVVVVRVRVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU74</accession>
    <name>A0A6A6NU74_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_324905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU74"/>
    <dbReference type="OrthoDB" id="5232919at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053244">
        <property type="entry name" value="HDAC_HD_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="179"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="709" mass="75648" checksum="30297167F54AE936" modified="2020-06-17" version="1" fragment="single">MPLSRRSSSTFLGSSPGGGGRMGMPLAEEKEEEGPKVKTAGEIAADWFEREMTGLQNGDANTNASAAPHSGIAAAADGSRTLGKAIVILHDQCYGHRFSRPRTAKWVLSSIVERPERIQAAVLGLAAAYVRLGGRHAEGRCPPTPLPPAASSNGASLNNSMAPAPFRIKKSSRELSLLDAAVTNVHGKKWMEELGLMCAAAGERLAAAGNEVSRVAVPTSNSNTASGAPTTTGTGKNSAKDKDKGTDEDERPEIHKGDLYLCPESLSAFQGALGGVCDGIDAVFRNAQANKNNSSIAAPTRAFVCIRPPGHHCSADYPSGFCWLNNVHVGIEYATRAYGLTHAAILDFDLHHGDGSQAIAWAHNARPAPPKPKQRQQWGQQQQPQQQQHNIKTHIGYFSLHDINSYPCEDGDEDKIKNASLCIEGAHGQSVWNVHLQPWKDRAEFWALYEARYKVLVDKARVFLAAHTARLRAAGAATPPKAAIFVSAGFDASEWEGQGMRRHKVNVPTEFYARFTRDVVALAEEEGTGVEGRVVSVLEGGYSDRALMTGIMSHVSALCAPPEEEDEGGRKGENAPGANAVEGVGFHGVKIKQEEDEDDELNEAMKGLLRGPVTDGNNVVANGTPTTEDITPYSPTWWSLPTLTHLDNTINPPPPPAPSKKPKAAAPPTYCSPTQSFTAKVVDPAKIRRSVSGPLRGGAPLSASPSRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUL2</accession>
    <name>A0A6A6NUL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_79411</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Peripheral membrane protein</topology>
            <orientation evidence="1 9">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M76 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUL2"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 9 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2455122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="245" mass="28756" checksum="1B9CDF90D97B799C" modified="2020-06-17" version="1">MAEREQQRESQPRPTLPQTTTSKTAAPDLPADLKEVYSWRKYFELITGQASKEDISKYRMARDILNEERDCKRCEADRDWLLQYSPVVTFLRENINKLGHDINSTNVRCKRCSTIQSGGFDADYGILICANWLRTRAEIEDTMAHEMVHAYDYARFKVDRGNLRHQACTEIRASMLSGECRFGREFFGRNQWNITEQLQECVRRRATLSLKNRPAVKDDVHSARLVNEVWDSCFKDTRPFDEIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVJ1</accession>
    <name>A0A6A6NVJ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_395695</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVJ1"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025638957" evidence="6">
        <location>
            <begin position="22"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="31"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="157"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="377"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2455514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="551" mass="60503" checksum="4B36AC0762608658" modified="2020-06-17" version="1">MHTLPTFALLLFSLLLHLARSASITQTWNLTWLHTSPSGLSHRPLISVNGAWPPPILVVALGDTLHIRVVNSLGNESTSIHWHGQHQVGTPQMDGASGATQCGIPPGGEFEYVFEAGPAGSYWWHSHNKGQYPDGLRGPLVVRDTERERLWGVEGEMAVTVADWYDEEMPGLLHAYLTGETEGREPVPNASLINEARTARFEVESGKTYLVRVISMSALAAHFLRIEDHDVTVVAIDGIPVEPAQTTSIRLSAGQRYDVLLHTKSNPTRNYALISRMDRLELQSRGQQPPPDATELYTNHGIVSYSAEFPDPSPLSPNETNFRPLNDMDLVPADGEELLGPVDEHITLTTSFTNRAGVGPRFSLCPHPYVSPLVPSLYTLYTLRALSTNPAVYGPAVCPFVVPHNAVVQIAVLNADDGPHPLHLHGHHFQVAGRGAGEWDGDEEALSKVPIRRDTVNVAPRGWVVVRFRAGNPGVWLFHCHMEFHLQAGMQVTIVEAPEMIGQETPLYADSEIQNCHALGLEAAGNCAGNVEDPLESSDCRRELTERDFWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVZ5</accession>
    <name>A0A6A6NVZ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED10</name>
        <name evidence="8" type="ORF">BDY21DRAFT_63008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVZ5"/>
    <dbReference type="OrthoDB" id="337270at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019145">
        <property type="entry name" value="Mediator_Med10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09748">
        <property type="entry name" value="Med10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="155" mass="17037" checksum="B001E632F3AFAB17" modified="2020-06-17" version="1">MKTVVQTLYNLIVTPLEFQGTSSEDALRRDISNLAAQLAHLHRAAPSVSVNIPPDIIQYVEDGRNPDIYTREFVELVQRNNQRLKGKSDALAAFRDILAADIAGAMPEMRGEVVRVLESVGVGSEVLDREDGRTEDQGLHIKKEEGVEEGEAKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWH3</accession>
    <name>A0A6A6NWH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_372708</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWH3"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000196">
        <property type="entry name" value="Cell division control 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="55"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="374"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="431" mass="49566" checksum="7FAB1648A759C1BB" modified="2020-06-17" version="1">MSSSKGAAPQTVTSKDPKAVAQAASDMRNIVRRKLTGYVGFANLPNQWHRKSVRKGFNFNVMVVGESGLGKSTLVNTLFNTSLYPPKERKPPSLDIVPKTVAIQSISADIEENGVRLRLTVVDTPGFGDFVNNDDSWRPIVENIEQRFDAYLDAENKVNRVNIVDNRIHACVYFIQPTGHSLKPLDVEVMRRLHTKVNLIPVIAKSDTLTDDEITAFKQRILADIQYHNIQIFEGPRYELDDEETIAENNEIMSKVPFAVVGANTEVTTPEGRKVRGRRYPWGVIEVDNEEHCDFVKLRQMLIRTHMEELKEHTNNMLYENYRSDKLTAMGVAQDPSVFKEVNPAVKQEEERSLHEQKLAKMEAEMKMVFQQKVQEKESKLRQSEEELYARHKEMKEQLDRQRQDLEEKKSRIESGRPLEEKGKRKGFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWI3</accession>
    <name>A0A6A6NWI3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1688-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_416164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWI3"/>
    <dbReference type="OrthoDB" id="2153176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="54136" checksum="17C24B5846F3D600" modified="2020-06-17" version="1">MGLFSRKSSKPTIGADHPPSTTSNSSLASPATPKISSSSPVGKSFSSMVEMPKAPDPSLDPAGYLRSIYAVRERSKLVLEKAKKNQLKHFTVDMTKFADTAGYVVSIIKRDYAPDYSSIPPHGRWQHFDVGGRPRIDQLMASWPSGIDAQERARRLIDLFLVSVLLDAGAGTKWQYKSKESGRTYRRSEGLAVASLEMFKAGMFSSDTAKPHQVDAAGLKNLDVATMAKGLQVSDSNPIEGLEGRTGLLMRLASALLNPEIFGIEGRPGNMLDYLLSHPSTQASSIPIVPLPTLWNTLMDGLAPIWPATRTQIDGVSIGDAWPCSVMPSHPTHPWENIVPFHKLTQWLTYSLMVPMTKLLHVHFAGAELLTGLPEYRNGGLLIDTGLLTLKPEDTKRGLANYEKNAQQKGQPSMEVVPLFPADDDVIVEWRACTVGFLDMLLSEVNLLLGLHGNDALTLAQMLEAGSWKGGREIAEVSRPNTKEPPIMILSDGTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWJ8</accession>
    <name>A0A6A6NWJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWJ8"/>
    <dbReference type="OrthoDB" id="4124983at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053146">
        <property type="entry name" value="QDO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17499" checksum="884D7962A3FCD79B" modified="2020-06-17" version="1">MADRDIPDVPVNFVPASAGEIIDLGAIKVRVMEDGSRTDNRIGAAEIVVPAGTPGPPPHWHEMHDETFLVTGGTLRFHVPGQGDIDAATGDYIVVPTRSPHTFSNPFEVEAKFFNTYTPAFYINYFKLLSILVKEGGGKMTPEVNERAMRGYATITLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX10</accession>
    <name>A0A6A6NX10_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mitochondrial inner membrane protease subunit</fullName>
            <ecNumber evidence="11">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_372870</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S26 family. IMP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="11"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX10"/>
    <dbReference type="OrthoDB" id="9996127at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037730">
        <property type="entry name" value="IMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041:SF2">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peptidase S26" evidence="12">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="12">
        <location>
            <begin position="96"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="18936" checksum="C4196E0C2EA96FEB" modified="2020-06-17" version="1">MAFVLVNDLLFETCRVNGPSMAPTLSPDFYTAGAKDTVLFYKNAGEMRRVRRGDIVVYHSLKYPEKLSVKRVVAIEEDTVILPWGEKGVYPGGKVLVPFNHVWIEGDNREKSLDSRHHGPISKNLIVGKAMGIVFPLSRMGRIDTHGPKRPTLVIERSAGAPPLEIGEVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXA0</accession>
    <name>A0A6A6NXA0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXA0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025610873" evidence="1">
        <location>
            <begin position="22"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="131" mass="14005" checksum="AA91F04F66E253D9" modified="2020-06-17" version="1">MTPRLATLVASLSTLLGVAKATYVWQPGSFAHSTLSNLCYNTHTWTVYTMAHPSIAPTTTITTTFPVWVSTVTVAGTTEYEGHVISPLSVPTVMPSALISPPSGFDSQVSCSLFQLLLLSHTPTLHLAPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXJ5</accession>
    <name>A0A6A6NXJ5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA mismatch repair protein PMS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_348354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXJ5"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000710">
        <property type="term" value="P:meiotic mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03484">
        <property type="entry name" value="MutL_Trans_hPMS_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.100:FF:000001">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000014">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000120">
        <property type="entry name" value="Mismatch repair endonuclease PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="6">
        <location>
            <begin position="217"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="5">
        <location>
            <begin position="809"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="386"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="461"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="502"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="565"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="665"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00070941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1041" mass="115177" checksum="0542520D0DADE4CB" modified="2020-06-17" version="1">MATIRAIEGRSVHQIQSGQVIVDLCSVVKELVENSLDAGATAIDVRFKNHGLEAIEVQDNGAGIAPEDYETIALKHYTSKLKTYDDLSTLSTFGFRGEALSSLCALSDFYITTARVVDGPRGAKLEFESSGKLKSTSMTASPKGTTVVVERIFKNLPVRRRELEKNIKREYGKVIGILQAYACISSGVKLSASNQMPKGKKTVVFSTRANPTTKENIINVYGAKAALGLLALDLKLEMQPSGLPLHLSSLPKSDGDNASRQVRIVGHVSRPVVGEGRQAADRQMFFVNSRPCALPQVAKAFNEVYKSYNITQSPFVFADFKIDTNSYDVNVSPDKRTIMLHDQAALLESLKSGLIDLFESHNQTIPQSQLTNRKLPSFQPVSTLVRLSSTPQRFSEDSRGKYDPDDGDAAGQDQAENAAQEESLFVSDGEEPSNSARISASNTNAQPEPRTSSGTQRRDLDLEEQPTLEILEDEGLSCDQQSQSESDDKVSKPTTGYDTQDPENRADGIRWKTRDGISVPEVSSDSISDEESIPRMTAKQKRQTQSSIMNAFDRMRPRQRPAETATITIGDTTRSMIIGSQESKRRRLNSSSYSKAGRRPGSAQFSSSLDMFRLQGIRSTKGHHNASDDGSDTQDADMPVSDPGRGDESAMEQLAIPEGRHEAAENEDDASDDESSGSTSPASVVQNESSSDERIDEEEMKKREEAHVAQMVAEAEELAARPPADNEKRATKVLKARKRKEETLNLVLILDTCADDISRNLSTWHDTLEVDEREAQDDRALQAEVDHDDSPEERLSLTVLKSDFAAMKVVGQFNLGFILAIRPRRPDAGHPTGKTTPLQSDELFIIDQHASDEKYNFERLQAETVVQNQRMVHPQTLELTAVEEEIVLSHSDALAKNGFVIECDTSGASPVGRRCRLVSLPMSREVVFGLPDLEELIALLAERSGAEVPRPSKVRRMFAMRACRSSIMIGKNLTAKQMERVVKHMGEIDKPWNCPHGRPTMRHLYRLGGWTRWREGDGVAGVDEEHVRHTDWIGYMRSQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXL8</accession>
    <name>A0A6A6NXL8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_348435</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[protein]-with a C-terminal TM segment(out) + ATP + H2O = [protein]-with a C-terminal TM segment(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66168"/>
            <dbReference type="Rhea" id="RHEA-COMP:16963"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:90782"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07543">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000049">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000054">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000071">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057255">
        <property type="entry name" value="2TM_P5A-ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047820">
        <property type="entry name" value="P5A-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23143">
        <property type="entry name" value="2TM_P5A-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="P5A-ATPase transmembrane helical hairpin" evidence="17">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="260"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="963"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="963"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2456274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1295" mass="143910" checksum="E3B166D01042468D" modified="2020-06-17" version="1">MAPPLVDDSQIKSATLQNPLPRHLHAYVWPFAFVWPVFLAFYLDEDRYERYIDGQEWTFVWVGSIVTVQSLVWLSTHWDVNLQALFTTTKAKDVNSAGLIKVIPIANAGAADICPLRRTVVGGKENVSFLFQKRRFLYSPEKGSFRALSYALDADPKPQLKTFQQSRGLSSPADIQRLQQHYGDNAFDIPVPTFTELFQEHAVAPFFVFQVFCVGLWMLDEYWYYSLFTLVMLVAFESTVVWQRQRTLNEFRGMSIKPYDIWVHRQNKWQEIHSDKLLPGDLVSVGRTKEDSGVACDMLLVEGTAIVNEAMLSGESTPVLKDSIQLRPGDARVEPDGLDKNALLFGGTKVLQVTHGTSSDDAPDTLHSVASGVPTPPDKGAMAIVIKTGFETSQGSLVRTMIYSTERVSANNLEALLFILFLLMFALAASWYVWQEGVSKDRKRSKLLLDCVLIITSVVPPELPMELSLAVNTSLAALSKFAIFCTEPFRIPYAGRVDVACFDKTGTLTGEDLVVDGIAGLSLGRGGPSVKTESDGAQSHLTAVAEAGPETTLVLATAHALVKLEEGDIVGEPMEKATLSSLGWSLGRNDMLANKVVAASKAGASHVEGVQIRRRFQFSSALKRQSSVATVFENNRQTGKKAKSTIVGVKGAPETIRKMLVDVPPKYEETFKYFTRNGGRVLALAYKYLSKEAELGQNRINDLKREDVECDLHFAGFLVLQCPLKDDAKKAVRMLNESSHRVVMITGDNPLTAVHVARQVEIVDRDVLVLDAPENDDTNTKLVWRSIDDKVNIPVDETQPLEPEILKTKDICATGYAINKLTGQKGWRDLLRHTWVYARVSPKQKEEILLGLKDCGYTTLMCGDGTNDVGALKQAHIGVALLNGTREDLDKIAEHFRTSKMKEVYEKQVSLMKRFNQPSPPVPPMIAHLYPPGPQNPHYEKAMEREAKKKGATAAAALAQQNSGANGAVTTTQQGNQQQLTPAQQRQAQAQKQVQGLADSLTTKMMESELDENEPPTIKLGDASVAAPFTSKLANVVAIPNIIRQGRCTLVATIQMYKILALNCLISAYSLSVLYLDGIKFGDGQVTISGMMMSVCFLSISRAKPVDQLSKERPQNNIFNPYIIGSVLGQFAIHIVTLIYISQYVQRIEPKDDDVDLEGEFEPSLLNSAIYLLQLIQQISTFAINYQGRPFRESISENKSMYWGLVLVAGVAFSCATEFIPEINEKLRLVPFSTEFKVTMTAVMALDYVGCWIIEKTLKQLFGDYRPKDIAVRRPEQIEAEERRRLQEIAEKERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXP8</accession>
    <name>A0A6A6NXP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fe transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_53145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXP8"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF24">
        <property type="entry name" value="FE(2+) TRANSPORTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2456526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="425" mass="46093" checksum="6CEEF7D28BD97879" modified="2020-06-17" version="1">MADRPQCGGGELDADNYDLPLHVAAVFLVLGASVFGAGFPVVAKKIPSLKIPAKVFFYCKHFGTGVLIATAFAHLLPTAFGSLNDPCLPPLFTEQYPALPGAIMMGSLFVLFVIELWLNGKVGGHSHGGPTGSNTHAGHQNKSANRPNISAPVPIKREYSFSSDASTEMGWDEKTEKTPYVEENEIPPLPAERNFDESNMPSEMPAWFIVFYEQYVRQREDMLRMINDGVKKKQEPVTTHDTNEKQMEPSLADVESGEVDPLVLKKMNLNITLLEGGILFHSIFVGMTVSITTDGFIVLLIAILFHQMFEGLGLGSRIAAVPYPKGNWRPWLLVLAFGTTAPIGQAIGLATRNTYDPDSAFGLIIVGVFNAISSGLLIYAALVDLLAEDFLSEEANMLLTTKDKVVAFTCVLFGAAGMSFVGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXX4</accession>
    <name>A0A6A6NXX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_287939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXX4"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="30"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="389" mass="41565" checksum="8144F749C90F8B3D" modified="2020-06-17" version="1">MLSSSGTLAFSTTVTTNPTLGGLILTSNRAGVVGLQTAVFLLEAGYNVTIVAKHFPGDQTIEYTSPWAGAQWRPHSTVDEPEQCKWDLETYEHLMSIIKEEGNHESSRDLPKSGTSPHPPTNVWFSQLVPSFRYRDNIPPKTVGLPDHTNVSGASFRTICINSTAYLHYLLARATSLGAHTLRRSLPTTSGLKAALDDLSTTTLPSPISAVVNATGLSALALVPDPNVYPIRGQTVLVRGEARAAVSLERGATASSPESVSYAIPRPGSGTTVLGGTKEAGRWTAEAEKETTAEILERCRALVPELLTGVGREGRMEFEVVDECVGLRPGRKGGPRVEGEWLSVEGGKDVWVVHEYGHAGGGYQNSVGSARKAVKLVGEGAKGRNRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY29</accession>
    <name>A0A6A6NY29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YT521-B-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_287451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY29"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057720">
        <property type="entry name" value="RRM_YTH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25701">
        <property type="entry name" value="RRM_YTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="368"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="YTH" evidence="4">
        <location>
            <begin position="510"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="626"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="742" mass="80404" checksum="3D1FECB0F4FA5C6B" modified="2020-06-17" version="1">MAYVWVQHWVALPVILEERPMGELPPDSNFMPADPARAGLSQDPSQQSLVKETQAPVPGSPAPVDARGAGGNAPFYSQYHSVPHPHPPPGRDPSRFPVPTSQAGYHPTLNQDGPSSAFNMGAVAGALPEYQSGTPAQSHLHGPHQQHHGHGQRMVTGASTPAVVYQLQQNLQYPGQSTQGYGNQPAHFGPGFAQSQYHQGQPQYLPTQSPSHGSFAQFNPGQQRPAGIHPVQGPYSGYAQQPPQYLYYPPPYGPGQPSPHALPAQPQHQQQQQQQQQQQQHQHQQHQQQGSYGRRQSFPSSQVPGQVQGDARMMTGNIGQYAGMGQPDYGASGYVASGGNPHVPRPPSEASIGSVPRGPPRKPKQSGHALWVGNLPPGTNVADLKDHFSRDATKDIESLFLISKSNCAFVNYRTEESCTAAMHRFHDSRFQGVRLVCRLRRSSAAAAGVPTGPSSMSTPRAASASPQRSPIVASGDEQQEDEPAKNQPDDPVTAATPLESSASGSSKVPEKFFVVKSLTLQDLELSVRNGIWATQAHNEEALNKAFETADNVYLIFSANKSGEYFGYARMSSPINEDAAEIIRTIPVSESTDAPDAPKSIPTPATEFAPKGRIIDDSARGTIFWEADLSDDESDDNVERKAGDDSPSQGAEVDPSVTTQTWGKPFKIEWISTTRLPFYRTRGLRNPWNANREVKIARDGTELETTVGRRLIQMFHRLVPPNTAPPGGMPAMHMGAGPSMRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY34</accession>
    <name>A0A6A6NY34_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin carboxyl-terminal hydrolase 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_50845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY34"/>
    <dbReference type="OrthoDB" id="5369841at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="65526" checksum="6B9FBB44A33BA109" modified="2020-06-17" version="1">MSLLQQPHLAEPHGESMDSSGDIWRIHNEMIRFHQTQADHAERIARLERRQEDDARIKSVWGPSSPFPGVLSGTPQQASQHRLSTPALPGLEDQNSLIGGLQLDPDDEPRRIGTTSRANSVRFDETANQGHWAQSSRSSLDFLQRTGSGLGGLPMTERSLSHKSDGRQSSAGHSVLSLPSGRANSLGMDSTFGVANSTNSSVDVPCVAPGLLILGSVPAIIRCWLNRNFKHDSLLYAAVCTGSYCSLLDSALIRRLEYQDRVIQSDDGVQSVKIDVYLPEAVPRGPSSSVPEGEHQLPFVPVEFKVTALDVPAVDSKPIQVFLGSDVLRAHNADILFSSNSMTIFDEFNTKFSIPLVRPENEQSFRSLRISVSSEGQGVGSANRAQNVKDEESEPSCPVSEAVPHTYGGTKAPTPIISGLGATQGFRIHGPYEIDDSKLEHQTSESKAEPSTPSAKFEKEASTPAESPSRNARSGSTSSLWGNWRKEGGKNVNSDWANTTKSGSATYQRRDQGIKVLKPTRSASRASSSSQQAAASPGASQSRFFDDGKRRTVPPSTGTESTEQQALRAPSLTSKASSGSTKESQGVTGKVRTSNPVGGASAFPWLNAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY64</accession>
    <name>A0A6A6NY64_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_322788</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY64"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000015">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000024">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="12">
        <location>
            <begin position="1"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2456474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="433" mass="45567" checksum="16B82D40B76C7806" modified="2020-06-17" version="1">MRSVAVTGLGAVTPLGVGFRRAWSRLIKGDCGIVSVADRAPREQYAALPSRIAGIVPEGPRDQGGWNSTEWLEKGDERRMARFAQYAMAAANEALEDAGWAPTRDNDLEATGVYIGSGIGSFDDVYDTSVAYSQGGYKKVSPLFVPRLLINLAAGHISMRHGFRGPNHASTTACTTGAHALGDAARLIAFGDADVMVAGGAESCIHPLAIAGFARARSLATDWNSTPQLASRPFDRERAGFVIGEGAGVMVLEELQHARARGARIYALLQGYGISSDAHHMTAPLASGDGAYAAMRRALRRAGVAPSEVDYVNAHATSTQLGDAAENKAVKRLMLEGPEGKDRANEINVSSVKGAIGHLLGAAGSVEGIFTALSVKEGILPPTLNLESPGDPPEDFDCNYVPKTAQRLPVKVAVSNSFGFGGTNASLVFTKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYH2</accession>
    <name>A0A6A6NYH2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">quinol--cytochrome-c reductase</fullName>
            <ecNumber evidence="3">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_346137</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="17">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="3"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYH2"/>
    <dbReference type="OrthoDB" id="5925at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000002">
        <property type="entry name" value="Cytochrome c1, heme protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000003">
        <property type="entry name" value="Cytochrome c1, heme protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 17 18" id="KW-0349">Heme</keyword>
    <keyword evidence="13 17 18" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 17 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="20">
        <location>
            <begin position="99"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR602326-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2456800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="333" mass="36671" checksum="CA76D9F1FFA4A26D" modified="2020-06-17" version="1">MLARSCLRATRSFGAVRAQTPGSRTGLRSASTSSGPQQARSPSNTLAISASTAVALGSLAWYYHMFGREAFAMTPAEEGLHATAYPWEHEKWFRTFDHAALRRGFQVYREVCASCHSLSRIPYRSLVGTILTVDEAKALAEENEYDTEPNEEGDIEKRPGKLSDYLPAPYKNDEAARAANQGALPPDLSLIVKARHGGCNYIFSLLTGYPEEPPVGASVQEGLNFNPYFPGTGIAMARVLYDGLVEYEDGTSATTSQMAKDVVEFLNWSAEPEMDERKKMGWKVLAASGVLFTLSIWLKRYKWSPLKTRQMVYSSPVKPSSPVPRVGSRAGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYH3</accession>
    <name>A0A6A6NYH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Frag1/DRAM/Sfk1 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_345896</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYH3"/>
    <dbReference type="OrthoDB" id="10032492at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="7">
        <location>
            <begin position="6"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="33276" checksum="351989FCA2A6C254" modified="2020-06-17" version="1">MARFPYWIVPVFSATVWLAMLLAMLLWWIVAEDSPKYSTMSQGQTIAFISDVGARTTMKPLFIAMGTTAVVTFDLVFILERWLRHRGKLERNTSWTQRILSVVSIFTAIAGGVGLILLSIFDTLRHPTLHNAFLGLFIVGYIISAIATCAEYQRLGIHFRDAPILRISFWMKLTFILVSIGLAIAFGVTQRRDQWNAAAIVEWVVALVYDGYVFSFAIDFISTNRSRRGTWHEEERAPGTMSMAALEANNAGAIQAGSGRFYGNGTDGAANGYTNGTAGYANGYTTRQKPTEPVSSSRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYU2</accession>
    <name>A0A6A6NYU2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_386329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYU2"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="360" mass="37882" checksum="099C3DE72287B690" modified="2020-06-17" version="1">MADSSPQQLRTKLTDLLKIQHPVLLAGMNVAAGPKLAAAVSNAGGLGVIGGVGYTPDMLREQIAELKGYLKDKKSPFGVDLLIPQVGGSARKTNYDYTKGKLNELVDIIIDSGASLFVSAVGVPPRSIVDRLHKAGVLYMNMIGHPKHVAKCIAAGADIICAQGGEGGGHTGDVPTTVLIPTVVAMCAGKKSPLTGAQIQVVAAGGMFNGQSLAAALMFGASGVWVGTRFVLCEEAGAPKAHQEAVRTAGFDDNVRTIIFTGRPLRVRRNPYIENWENNRQAEIAELTSKGIIPVEHDMENMGDDIDDDTMDNARPFLMGKAAAVVNERKSAKAIVDEMVGDAVKLLATGNGYVVSKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZF5</accession>
    <name>A0A6A6NZF5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 60, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_364024</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZF5"/>
    <dbReference type="OrthoDB" id="1733909at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="585" mass="61659" checksum="E4DA73F8CCA9FC9B" modified="2020-06-17" version="1">MQRALASRARATALSSSSRIRQSSFNLTSKRFAHKELKFGVEGRASLLNGVETLSKAVATTLGPKGRNVLIESSYGSPKITKDGVTVAKAISLQDKFENLGARLLQDVASKTNEVAGDGTTTATVLARAIFSEMVKNVAAGCNPMDLRRGTQSAVDAVVDYLQQNKRVITTSEEISQVATISANGDTHIGKLLSNAMEKVGKEGVITVKEGKTIEDELEVTEGMKFDRGFISPYFITDAKAQKVEFEKPLMLLSEKKISAVQDIVPALEISQQLRRPLVVVAEDIEGEALAVCILNKLRGQVQVAAVKAPGFGDNRKSILGDLAVLTNGTVFTDELDIKLERVTPDMLGSTGSITITKEDTVILNGEGSKDAVAQRCEQIRGVMADPTTSEYEKEKLQERLAKLSGGVAVIKVGGASEVEVSEKKDRIVDALNATRAAVEEGILPGGGTGLLKAAANALGSVKPANFDQQLGVSIVRNAITRPARMIVENAGAEGSVVVGKLMDEFGSDFNRGFDSAKGEYVDMIAAGILDPFKVVRTALVDASGVASLLGTTEVAVVEAPEEKPAAGGPPMGGMGGMGGMGGMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P075</accession>
    <name>A0A6A6P075_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_286251</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P075"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="74"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="414"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="503"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="667" mass="76560" checksum="C96ABBD632899820" modified="2020-06-17" version="1">MAADYRDNGYEWDPVARRKKRERIKLETAHPGLNSMWDDLEKVPIIPTEKAKQPASISRKLKGFQLEGLNWMIKQEKTQYKGGLLGDEMGMGKTIQAVSLIMSDYPAKNPTLVVVPPVALMQWSNEIGEYTDGKLKVLVYHSTNTKTKKMTVKELKKFDVIMVSYNSLESLHRKETKGWSRGEDLVKEMSPLHAIHFHRLILDEAHSIKQRTTGVAKACFALKGTYKWCLSGTPVQNRIGEFFSLIRFLGIRPFADYFCKRCKCAQIHWSLDKDYRCSYCKHSGSEHVSVFNQELLNPITGYDAEAREEALDKLHLITSRIMLRRVKRDHTSSMELPAKEIVLRNEFFGEIERDFSSSIMTNSSRQFDTYVSRGVMLNNYANIFGLIMQMRQVADHPDLLLKKHAEDGQNVLVCNICDEPAEGAIRSRCKHEFCRSCVLSYVETCEGNDSSADCPRCHIALEIDLDQPDIEQDTDLVHSNSIINRIKMENWTSSTKIEMLIYDLFQLRSKKQTLKSIVFSQFTSMLQLIEWRLRRAGFNTVMLDGSMSPAQRQKSIEYFMNNADVEVFLVSLKAGGVALNLTEASRVFIVDPWWNPAAEWQSADRCHRIGQKRPCVITRLCIEDSVESRMVMLQEKKANMINSTINHDKVAMDKLSPEDLQFLFRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0A2</accession>
    <name>A0A6A6P0A2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_38996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0A2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="22239" checksum="66F3989F0A51CA45" modified="2020-06-17" version="1">MATAIILPMAATSRGRTPQEAHSLARFAWHGRRVSPPHAQFERRDACATAKYLPATTTAAAAAAACVRPCTASREPREPPSLPTAGTTPRNPQIRPHPAFRASLFARWPRRSSPSTPHLPHPFFLFPCGEVVARRLGTSEPVRTAKTRSCEGLPHSGLRRQNQEGAFALPSPEDRRAVVDTSRFRTLEARREHIWAGEPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0M1</accession>
    <name>A0A6A6P0M1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_345448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0M1"/>
    <dbReference type="OrthoDB" id="5343159at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025664182" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="158" mass="17801" checksum="E231ABB7B9334298" modified="2020-06-17" version="1">MIHFRPLNLFVAFAGLFSSTLADSLERYECFCAGNNLSGFYFEYHYNSDRLGETVVAQQQCHDVIGNPPPCSTDIYYEIDICGTDANGVEFCYDKDVFSGDDYTFDGSERELNTDNAQDLGGLESYCQSVCEYMDPGLSTDCEIYGCKAQIFYDLEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0P2</accession>
    <name>A0A6A6P0P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_32588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0P2"/>
    <dbReference type="OrthoDB" id="3979469at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038882">
        <property type="entry name" value="Rcf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153:SF1">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13317" checksum="5F90FAE5D19586ED" modified="2020-06-17" version="1">MRAHGRLKTDEQANAAAWEAARGAGYGAAKWGIFATAVAATGYAVSPLYRGLTFQFKVFLQMSLMTLGASIHADRALRAHERRVRHNAALARDAAVWRSVEDEFESRGTPGVQSESGVRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Y2</accession>
    <name>A0A6A6P1Y2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fumarate reductase</fullName>
            <ecNumber evidence="4">1.3.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_284836</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Irreversibly catalyzes the reduction of fumarate to succinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Y2"/>
    <dbReference type="OrthoDB" id="10252157at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF12">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0274">FAD</keyword>
    <keyword evidence="1 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="5">
        <location>
            <begin position="17"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2457742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="492" mass="50570" checksum="DAC9AC0C4C02D626" modified="2020-06-17" version="1">MATTSSIPKPSSSKPTAIVIGSGLAGLSAASTLLSHSIPVRLLERAPKPGGNSIKASSGINGAPTRWQPGPEPDTLFYSDTVRSAGGAWAEDTARREKLVKTLTDGSAGAVEWLVDGKGVDLTKVAQLGGHSRARTHRGQGKLPPGAAIVTALLGQLNASPLFALETNCTVTKVLRPPAGRPAAGVEYSCASAGASEQTTRAVAGPVVFATGGFAGDAHGLLARHRPDLSGFPSTNDPHPGSTPLLTAAGAATLDMARVQVHPTGFVDAAAAGAPLKFLAAEVLRGEGGVLLRPGQAGLERFVNEMETREHITGAITAVAGVPDELPTKQWDVSIVLDEGAYEAAKSHIDFYIFKGLMRKSTVGELGQGAQEALQAYADAAASKAEDKFGRKSFGHWRLESVQPDSVVYVGRVTPVVHFTMGGVAIDERARVLDDGGKPIPGLWAAGEVAGGVHGDNRLGGSSLLECVVFGRIAGEEVAASIGGGATEQTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2H3</accession>
    <name>A0A6A6P2H3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2H3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025682444" evidence="2">
        <location>
            <begin position="16"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="118" mass="12179" checksum="C612274AB5C000AD" modified="2020-06-17" version="1">MKTAYIALFFATVMALPRPQDTEVPAGLVDAVVDDVLAAVGDVVSAVPDVNADVEVENPVAAEVDLDVDPANADVDLDVDAPIIPTLGDDEDEDDDEVASTPSVPESLPTPTPEVTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2V1</accession>
    <name>A0A6A6P2V1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7624 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_215372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2V1"/>
    <dbReference type="OrthoDB" id="5230484at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056041">
        <property type="entry name" value="DUF7624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24616">
        <property type="entry name" value="DUF7624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7624" evidence="2">
        <location>
            <begin position="670"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="791" mass="86693" checksum="FFF89E04829821F8" modified="2020-06-17" version="1">MQNQIERSRSSGNQHNSSHSDSLAPPPSPYPATVDPSPVDSNGTTTTEIEDEPTDDAEEVQSQLSSNRNSNSHRSFSSTGADSMESPQSPEALTKLDTTAPSRADPDPDAPQSVIHAPTDYKQFRQGAKRSSPNRTRSRAGPDSPGDRSDHTVVSPSTPEPNVHPDSVKHTSPIDTALPPIKTTDKATPRAHTRQEAEEERRRRLSRRSNSLEDIAEAPDGERGTEDEESTTQKSGSNDSPSTNDGQSADRPGSRAATMGHAAEQLKEVDLEIRELKTALSECWTLCNTLAKLSQNHRERMFNYAGKGEVQEQAWRSCWRLCQKLYESREEDHASQVRPTLELCRDFCQALFEVRQRGDPVNDSVLRVSFELNNHLYNTQDRNLPVPFRERTLDFYLTLCHRLMKQRTILPAETDALLRSCWSLAEMLFSLRQNTRDSKPPDEELLGSAVQACWELCDLFREGWNQVRPDRGTPRPNQASFPREYHQYGYTTYGQPQHGVTSTPSVRSEQSRSHHSRSTASIDESSYHSVRSQAGGQTSGAPSRAGTTNNSPQGPARGGGDVTGNTLLPETPTTIFDDHQDLSPDEAPVPNILVLGPENATTRTHNRWSSAASTLSAYTDSASGSSSMLNGLGGPMSAAVTNANEGMRPTSAASSTATGSTVSGPSAVGSDPHLERLKALILRAAMNTGFRSGSGLSLPAFVRSLPATAFGATQWQVRLLDAYRRLVVTDPTLRGPDVAKRRYTAAEVGRAVQWMERSEQFGWFRDLYRFVFGFYPEEAAAGAGPAAGFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2V8</accession>
    <name>A0A6A6P2V8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_284409</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2V8"/>
    <dbReference type="OrthoDB" id="2341546at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000003">
        <property type="entry name" value="C6 transcription factor (Leu3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="695"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="700"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="787" mass="85544" checksum="1B6AEF180BB9BD83" modified="2020-06-17" version="1">MDGSPAGGGGSVALGGAGPQHGRNGSVSQYTTATAASSVSPTSARAQLQHNGSARKRTISNAGLESSPSSSIHHDEDLLLAGDELETGGQGRRRHTTGGTGSKRACNKRACNQCKQQKLRCNVQEEPFEPCSRCKKQNLECRIDDNFQRVAKRSRHLEMEREIELLRQQNQLLSGQMAGPPNVSLVGSNPSHNTPNSAIYSGLPAGPEQFLGSHEAAGSLLDLKQGIEGYGASPNARQLIRSLEDVVLAPDRIQELFVEYWNCYHPFLPLLDNTKSPDQYFASSQILFWTIISIASRHFQPDTDLLTKMTGPFTRLLWTQLSKVPQDHHIVRALCLLCAWPFPTSSTSSDPTFMYCGLMMQIAMQIGLHHPSHAQDFSRFHVRLQEEDIQDRVRTWTACNIVAQSVSTGYGQPSQTIYGPTLAPRAQERGQEMYQIPEDLSARLEIARFCNIVTKSLYSSQSESVRMTNDDERANMASILAQNLADLESRLTNGVLPLTVTDTLYLHSASLHLRLWAFFDTSSASTYRSDLLQLYHATKNFLEMVFSLRDGTPGIGGGESSLIYATNYLMQMTLAAGFTLFKLLNSFFARQLPGLVDEGKRLLTGTIQSIREMSVTNNDLPQRLAEVLAQLWRASPAAQSASTNGNTPTMATSVGPGAVDVDDSLQLRVRCRQSMSLVFDSVWRWRDEIQGKSAAGNLDNAVNNPTNPEASSSSTPVRVLGAAVAPLSESSTSMEPALPSLGLPGGNGIGGASAGFAYPNASDMFDTLGWFLDGVDGSMGGMTWGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P334</accession>
    <name>A0A6A6P334_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="5">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371092</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 5">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="5"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P334"/>
    <dbReference type="OrthoDB" id="6038816at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF11">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025585434" description="AA9 family lytic polysaccharide monooxygenase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="7">
        <location>
            <begin position="21"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="228" mass="24660" checksum="CCCF2B0713A70899" modified="2020-06-17" version="1">MKPSVALSIAFAACFNVATAHYRWTSLIVNDDVTSPYEYVRENSPNYNSPITDLSSDDLRCNEGTMAKAASTKVYDVKAGDTIGMALDQAIFHPGPILAYMSKAPGDVTEYDGSGEWFKVSELGPTFSSGQINWPASNRDRYTFTLPSETPSGQYLFRMEHIALHSAGAPQLYMSCAQVNVQGASSGSPGPTMELPGGYSMNDPGLKLNIYSPVPTSYDMPGPEVWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P358</accession>
    <name>A0A6A6P358_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_273793</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P358"/>
    <dbReference type="OrthoDB" id="7608935at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="119" mass="13409" checksum="82CCE9696037F43B" modified="2020-06-17" version="1" fragment="single">CPICGVPGHARAVCPTRVCDYCTAKDDHVSRRCPIYTPCERCAQRGHTAAQCTADLAPGEKCCLYCGERGHDDEDCIKTWSKYPERAKRLKEHEKMSRDQLFMSCYRCGGNDHFGDDCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3K4</accession>
    <name>A0A6A6P3K4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_207078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3K4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="124" mass="13581" checksum="6B9408500A6E4459" modified="2020-06-17" version="1">MWWCVGSMYTYAGRRVRRRVDAWTTGFAGIALLEVGMLTEGSCTGSVGGFFATVGVVNRIGVSYVRLLVFLAMCFELSALFEPRTSCCIHCFPRSPSIFPFSHSNFPNSSLLAVCGPRPTVRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3X8</accession>
    <name>A0A6A6P3X8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_209778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3X8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="271" mass="30641" checksum="BDB17640FE7AEAA6" modified="2020-06-17" version="1">MCGTYLWACGECHRQQELVDECPMRASHRPVRRFPPWNKHTPDPMCCECGKSRPIPIDHPPYPPELVHPKSPCQRLPPIKDLLPAGHCSNVQCSHIADEAVVDPQLLQRPEPTSTVQPQVRRGKDTRDRPYYAPPQNQAVSRLRQMNELSPNELSPTARSQSGTSNTGILSRRAPPAAPSGLPLVKRDEPPRSTPSQQYRSDMGDRPLFPLPARSLEERQQTRSNVFNRVEEARDSIAAQAPSSVRCGPWEDTWDQMRSDMLGDPKRKRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P419</accession>
    <name>A0A6A6P419_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_370743</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P419"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000010">
        <property type="entry name" value="Calpain 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF425">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="13">
        <location>
            <begin position="149"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="587"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="599"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="629"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="643"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="810"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="906" mass="103320" checksum="4C915CF09224CC74" modified="2020-06-17" version="1">MSVAGSGNFEEHRPPPSRSESFQKDGMALDDRFYKYWDRFTMHKRLPNPPFRENDDVPALEHDVEGLPAHQPVLNKEGVITSQNAIRSYNEAAAICKAKVEAIVDECKRLNIKYTDRLFYLDDRDTLASLHADEEPTSLKGIEGVGSVKRIEDVFEKPEFFIDGATANDVHQGRVGDCWFLASITALSGKKDLIERLCVARDEKVGVYGFVFFRDGEWISEVVDDRLCLKPADEHMQNPTEYVVTVNGDRNPLYEGLQSMSYQVMPMSKEWREQVRKGSKALFFSSCRDSNETWLPLIEKAYAKAHGDYQAIEGGWTGEGIEDLTGGVATSIVSENVLDKDKLWEELKQVNKNFLFGAGSRHQTSSDDDPLDEQGFVRSHAYTVIEAREVKEHRLLKLRNPWGSQEWNGPWSDGSKEWTPEFMKELNHTFGDDGVFWISYRDFLRYYSDMDRIRLFGPEWTITQQWTSVNVPYNPDYLPTHFQLTLTKASPVVLVLSQPDQRYFTGLEGRYSFQLHFRLYRKGSRRYLVRSMNGPGSNRSCSAELDLEPGTYEVYMKINADRYVGKTTRRQIIAMYRERKREKLQTVGASFDTAHAKGRLRDMEKANERAERKSKSDRRKLDTVVDRAKNRKERARSKARQKRKDEEHKRRVEAKKAVVRAEKETEKKKTEEAEKEKTKEAKKEKTKEAEKEKTKEAEERTEKEKAGKEEAGTQLPIREKVEETEKNAKEETKATIEEKAGKVDPESESKKPEESKTKKPETAEAKEVSAESTTDESPKETPPSSDGSKEAPNATADGAPPRVPTAPPTEIEEDSPAEESDAVSVSTVETDDFEWDSDVDRSVSSDEDYQEVIQAEEDDIFASDPWNATCVIGLRLCAQDENASVEVVNPADTPSFRGLRGALSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P581</accession>
    <name>A0A6A6P581_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOSC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_283767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P581"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="194"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="358" mass="39431" checksum="AA9EFA43E4BE5DC5" modified="2020-06-17" version="1">MELSTLVRYLLTATTILIPATLFVLQLRARNNNASNKTSPPPPLPPPTTVASLRIYPIKSCRGITVRSTRLLHTGLELDRQWMFVSAEDKKFLTIRQISKMTLIDTALQPLGDAIAADTQLVISIRGADPPVAVAVPARPSQEHLAAHATRSTAIIWGAAVEAWEYGPELTGPISAFLGRDVRLVYKGGATAPRRLRGNGAPQVLGRTGSVGFADVLPVQIASEASMADLNRRLKEAGEDEMEIERFRPNIVVRGTEPWAEDTWKTVRIGGEGKGELVIDVQAHCARCRVPNVDPNTGIENKQQPWDTLMGYRRIDEGIKWKPCFGMICVPRNEGDIEVGMKLRVTETTNEHRYITGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5A9</accession>
    <name>A0A6A6P5A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5A9"/>
    <dbReference type="OrthoDB" id="3911455at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="437" mass="47381" checksum="72FBBFB96B83F9FB" modified="2020-06-17" version="1">MASPNTLPSTTHPSFPARFLFDDTAEAAPSPSPLHRGPSLPPNYTDPPPHSLEKPPAYDLPPPPTYTPLDPSPPAYILRPPYILAGSPSDTALVPRYHFDLVRSRAGAEHALRVRRLGARESKQVEAWLREERGRRRSAACGTHGGGALDEDDEDGGARGLFAMGNAARTGSVASSSATTTTTSSLLARVRTSSTSVTAASTSGSSSTGSVEDPRCRGCGSSGPAPQPFRLPDHLAYDAAETMYTIARVYTYSRAPRGTARSCPLEIRGQRTHTVSGILELSKDATGASNLLRRWRFDRVTRKVGGDALRKENERKMARWGYHDEDEWDRDVMFAASGKIGGGGGGGGGWRRKSWGLGLGKGDGEGNGKRDGEVEWKMKWKGKERVVAWETDEGCDRGGVKLGILGGEMETRLRDALVTCWLARRWFAGSLRWDDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5H3</accession>
    <name>A0A6A6P5H3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_199973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5H3"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="438" mass="47135" checksum="5257ED3EF39AFE28" modified="2020-06-17" version="1">MQVNPGGGVRRNPKRKNAGAYSTAANDSAPSVVEIDRAFEHHLKVMAQGGTWGDNMELTAFSAAYKKEIQVFQGSVNYVIDAGNCDGRVYIAYHTWEHYSSIRNLDGPHTGLPSVQVKVLSPDEEQRKTEKLAKPVEVQPWMVEVVIKSLPFLADKKVVLRALEQSHGNIDNAVSKLLEADDRGSASTHESSSSVEREPDSDDEALNGPNKKRDRNLSRANLTRTVSPRTNKPRRRLYQRRSPLSRTSSQGSQEASSRGSSASPAMSGIFQLPGAQGIDDGFQLSRATSFDELGRDLQKAGSTIAPSPSPAPSSVTGSEAPAPAKGLAPPGMGRVKLNPPKAPDSDAGEPADSTAGKRTQQRQPGPQRRRAGPTARERKDQKKAAQKAARKERAVAEAKDKTATDGVADKGDAQKLPIMTKGKTFAPSLASDVKTLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5Q7</accession>
    <name>A0A6A6P5Q7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA ligase</fullName>
            <ecNumber evidence="7">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_377751</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="7"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5Q7"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3260.10:FF:000004">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000009">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF9">
        <property type="entry name" value="DNA LIGASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="10">
        <location>
            <begin position="578"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="665"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="811"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="962"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="812"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="828"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="839"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="851"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="969"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2459330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="993" mass="104878" checksum="2B5FE5F9CC110248" modified="2020-06-17" version="1">MPGPGPSAPPAAAAPPAKRRRRNDGKAAPRPPARGLDWFFARQRQTGGGGAAGTPAAAREGEAEREGGRAGEARRLPDEADADADADADERLARRLQDEWDREAAAGSTAAGGARPGNGADEEDKEDGGGAVAPAARPRPPSAPTASPARPGNTLALLPVAAHEDVGAAAAVPFDESPLSFAPARYLPALRERWAAGGDGGGGGGGATYALLVRCFVLVGGTSSRIRIVDALVNLLRTLIEGDPESLLPAVWLSTNAISPPYIDLELGLGGSAISKALKKVCGLDNQGLKTLYNKCGDAGDVAFEAKKRQSFTLRKPKPLTIRGVYEGLVRIAKCTGKGSQEGKQRIVDRLLQDARGAEESRYLVRTLVQHLRIGAVKTTMLIALSRAFLLSKPPGADFPTKSPQELASLKKEDLADLYARSEELVKASFARHPNYNDLVPTLLATGVCPELLARCGLALHAPLRPMLGSITRDLADVLAKLGDARRAFACEFKYDGQRAQLHCDPTGRVSIFSRRLELMTDKYPDLVAAVPALRGDGVRSFVLEGEVVAVDRGAGAGAGALLPFQTLANRARKDVRLGAVQIDVCLFAFDLMFLNGEELLDRPLRERRELLRSLFVEVPGKFTWVRSLDARAEEADKVRAFFREALEAKCEGIMVKVLDNPAGNGAGDEAAGGEDDGPAAPPPTPRKTPKKQGKKTAALPSAAAVADRPQAQQPPPSTRRKALLATYEPDKRLESWLKVKKDYDRAAADTLDLVPVAGWHGQGRKHKWWSPVLLAARNPESGTLDVVTKCMSGFSDRFYREMRARYDPGVLGDGGAASGGGAAGGDDGGDEDDDGAGDGEASGGDAGSGDADEGDPDDAAPDRPPSPPSGAPRNVVGAKPALVTYSGPEPDVWFVPGEVWEVAFADVTLSPTYRAAVGLVSDERGLSLRFPRFLGRREDKGVEEASEVGYLAELWWRQEARGKGEGGGDGEADGNGAGEEEGNGAGEEEGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5T8</accession>
    <name>A0A6A6P5T8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_338048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5T8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="183" mass="19789" checksum="CFF2C7EB75AF3D31" modified="2020-06-17" version="1">MLYFLSSRSMFPQGLPQTRSTNRLTSTARHRRRCTNHKFNSTTILYPTTLARVPKHPTTKTSIRDLGTLITRNLGTSPSRPSQTPLQLPPDSHPNPSHDSVPPTAGSAAPRRDAMRSNPGAPRPRMGGLGGVAGGGARVAFLGARSVRRQMSRVALGSDGMQRRRESASRGASGVRGGGWERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P676</accession>
    <name>A0A6A6P676_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_282166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P676"/>
    <dbReference type="OrthoDB" id="409928at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="22487" checksum="12CF7B58FFDFBFB7" modified="2020-06-17" version="1">MSLVNLANVCSHLQNASKARLGLTSIPVSKLHVALMLALQREGFLSSVTLGGANPPANLVQGNPSPPADELVAAQKEPEPSADALAAEPWLIYDSRDWTDMVRWGDDAEQVVPRNLARRRLWLGLKYWDNEPVLSRMGLISKPKKRVILNSAHLQKITRGFEANFVKGLRRPGECIFLNTDRGVLESRICAEKNIGGMALCRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6F6</accession>
    <name>A0A6A6P6F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_317275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6F6"/>
    <dbReference type="OrthoDB" id="3661438at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="18653" checksum="118D86D834D8F46B" modified="2020-06-17" version="1">MQNQPEEDAGKVLYREGGVTWRIIARHYVNMNITFAKDVLPALSGVAEYVHMGIPSAGKYLAGLWEGNLEEQLLWCSYDSAKCHRPPSYTTPSFSWASRIGSLRWKSPSAQSERIFNIVEARCDVQGPGEFGQVVDGNLKLRGQVAQVERRLEQQKGLVRGKKASNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6I2</accession>
    <name>A0A6A6P6I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6I2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025485241" evidence="2">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="18229" checksum="F386AB5035BCE9BA" modified="2020-06-17" version="1">MVRLLNFAAPALLATVAAASFAPVFGNALERREECTATVTITYCPPEAPSVTMSSMPPPPESATASEYPGTSEAAVPPEATSETTAPAPAPSESAPAESGSAPPASETSAPVESSPAESSTPAESSAPASSTGAEESTPASTGTAETPTGTTGAAPPAETTGENSAGKANLNAGIVGLGVVCAFFAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6T6</accession>
    <name>A0A6A6P6T6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase F(0) complex subunit e, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_281630</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase e subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6T6"/>
    <dbReference type="OrthoDB" id="2125027at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008386">
        <property type="entry name" value="ATP_synth_F0_esu_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05680">
        <property type="entry name" value="ATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 11" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="87" mass="9979" checksum="34880410EBC304B4" modified="2020-06-17" version="1" fragment="single">VLRWSALAFGVFYGAYHQWTITSQDRMNAINREYERKAQLIEKAKAAYIKKTMPSESKTASGDVISDPEDPRFDLEAYLTLMETGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7I4</accession>
    <name>A0A6A6P7I4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylethanolamine-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_384369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7I4"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030162">
        <property type="term" value="P:regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF148">
        <property type="entry name" value="CARBOXYPEPTIDASE Y INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025502417" evidence="1">
        <location>
            <begin position="20"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="219" mass="23882" checksum="C9D2499586FE4E4D" modified="2020-06-17" version="1">MACLFPVMLLLLVLGLANAGPPDQAPLGNAHNEEMLSVRAELKKAEIIPTVIDDFIPYISVNVTWPTGKTADLGNTIKPSKTQGMPDVHLSADMTSSAASNMTYTVAMTDPDAPSRDNPEWSEICHWIATNVSLSSASGLDEVMPYYPPGPPEKTGKHRYVLLAFAPANGTTAPLDLTKPADRQHWGYDDERMGVREWADENGLVPVGANFMYEKNKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7K4</accession>
    <name>A0A6A6P7K4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_181720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7K4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="219" mass="23867" checksum="95533B775E7DA916" modified="2020-06-17" version="1">MGKPGLPAVWPAHPSSSFHARPVIGPHAPCVECTLTFSPRPRLRRRRGVLSEVTSLRWHRASCSGSCCAVNHPPARRTSWPARRLRPCLLLISDCAAESGPFSTRAAHGIGERPQAPAPRIESGCRLAALPTQGTERSLAMSPRATHTQSPPIVPGVAPTDGARWYPMRLPSTAVGRLRLVPAARLDRIEPTSRQRIVAAVSTRQAPPHFRPYHEPPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P818</accession>
    <name>A0A6A6P818_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_180822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P818"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="18672" checksum="626391CFBC2AA139" modified="2020-06-17" version="1">MRKKIATRATRSSPRKNKDPPQIRPLRWLLPPPPTPPLLPAIAIAANLHRLQAPSNTDPSAHEGRASDTEASDFGRGWPRANGSAPAWPVARSGGRRQLAVGGEGVSGLPTQAVLAALVELSAMTTTSTTNHRPARHFANEGPKAGRQLVCRLLLGLHARQFQCGSIAATLKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P831</accession>
    <name>A0A6A6P831_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_361897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P831"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="239" mass="26856" checksum="A1C70C1FE71F921A" modified="2020-06-17" version="1">MSLDDFEIADCQKFLDIFSKWPDPTWGFFVYATYSLSTTEGDDERPSTADMPAPIAPDARFQRVLDKLRAYASAQLLLSKPAPYGQRILDTLRLVPAARLPGASLDDVRAHFRTHIDEVSPEPHVREDKFGPGYSWCLVVDDESLASVEAGPEPLTELPEGTRYRKATVAETGVWVRAVHVGWDGRPKVVAQMGRGKSGQIVWEGSLKVCPRAMMKLWWRAWDGEVTKEFRGADKVYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P889</accession>
    <name>A0A6A6P889_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Galactosyl transferase GMA12/MNN10 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_281011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P889"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000117">
        <property type="entry name" value="Glycosyltransferase family 34 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF5">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2460104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="491" mass="55433" checksum="3025B45F8C470929" modified="2020-06-17" version="1">MSLSRSPSPQRGGGWSSPGLTAPYNSSGHGGRGGSAAGSGRTSPVPAFANGANVTWATAQARSAEVLRGGGRGDGSRTRGGGFLGGHWRRISIGLPQWRSGGGGIGAQHFAEKEKLGRGRWNIGGGGVSGGGGARGKVMQILAFFGRAIWRMRLRLAIVLGILLLVLGFYVTPLHRLYRRSSYLGGGSKYVIILGANQGGGVMEWKGPREWAIERDSVKNKKKYARKWGYELEIVDMSTKKRYAHEWRESWEKVDTIRNTMRKYPNAEWFWWLDLNTFIMEPSYSLQAHIFNNLGENTYRDINVYNPLNISHPLTEEYLDPETRSTVGDGDPSSINLIVPQDCGGFNLGSFFVRRSAWTDRLFDIWWDPVGYEQKHMQWEHKEQDALESMYRNQPWVRPHVAFAPQRRINSFPIGACSDNGPDPNIHYQEQDRDFVVNMAGCEWGRDCWGEMYHFRQLSNRLNRNPWEKFKDWISDGIQAARNRGKEDKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8F6</accession>
    <name>A0A6A6P8F6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_408203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8F6"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF24">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 3, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="333" mass="36523" checksum="85F3D00B083C790B" modified="2020-06-17" version="1">MTPLPSTLTTLRAALFLIPWLLLLLAADAALSLLLLLKPLAPRPTYDASSAIACGGGGSARATASVQQPPDRTTSSDLSDLSALVGGASAVVVANHVAWADFYLIQEVAARAGMLSRCRWFAKSQLRWVPFLGWGLWAMGMPLVTRKWASDRKEMRKVFDGIVEGALPIWLISYSEGTRYTPSKHASTTSWCAAHNKPTPTHTLYPRTRGFVATVQALRRAPHVRFVLDVTVAYARVGPAPSSGSRGGTPLLAWLDAAAPSFWQSLTTPDLEREGYRFYVHVDAFEVEGLPREEEGLAEWLEARWEVKGKRLEGLRRRLERGEETEGWAAAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8P2</accession>
    <name>A0A6A6P8P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_279994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8P2"/>
    <dbReference type="OrthoDB" id="5372703at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="1">
        <location>
            <begin position="7"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="200" mass="22469" checksum="0E28611EAF5624AB" modified="2020-06-17" version="1" fragment="single">SKQENDVKTPRPNITAGLRHSTVVEALVARGLSEEIADLFLKDLQRQQWLLSDPTQQALPIRFPPIVVESKSYATGKSVFEAQNQASVSGTCMANLQYKLTDLTKRLSPESHSFNAPLAFSICTEGPHMELWVHYTTTSKGGVRKYNMNILETCHASIEKWVREFLMVVDRVMSWATGDFLNDIAEQLVLVESAAREQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8S9</accession>
    <name>A0A6A6P8S9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-deoxy-D-gluconate 3-dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_315446</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8S9"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000398">
        <property type="entry name" value="Probable 2-deoxy-D-gluconate 3-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF5">
        <property type="entry name" value="2-DEHYDRO-3-DEOXY-D-GLUCONATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2460278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="28261" checksum="7B7E41A54A218F14" modified="2020-06-17" version="1">MPSVQELFSLAGQTAMVTGGTRGIGQAMAVAMAEAGADVLLVQRDTSNTETKSLIEALNRKATIYAADLSSHDSITALTPTILADGHRIDILLNCGGIQRRHPAHQFPSTDWDDVLQVNLTSVFTLCRDVGAHMLSRQPAAPGSAGGGGGGSSSSQRRGAIINVASLLSFQGGITVPAYAASKGGVAQLTKALSNEWAAKGIAVNAIAPGYIATEMNTALLNDEARAASILARIPAGRWGSPEDFKGAVVFLASRASGYVSGEILTVDGGWMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P995</accession>
    <name>A0A6A6P995_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_280393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P995"/>
    <dbReference type="OrthoDB" id="2279190at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF6">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="164" mass="18227" checksum="2DBF1B5F7965B492" modified="2020-06-17" version="1">MADNGSDSEPQARTMAQQEKQLNAKKQAKRDAGLQSNRSRSASRRARRQRIQQGQQEGKYMKTASLEALEEADANGELQQMQNFERIGPDSTSMDGPVTKARAMRGEIPMRGTNPNQPYQVDPSEAKKGSLEEQDGLRLRLEANLDVEVELKASIRGDLTLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9D1</accession>
    <name>A0A6A6P9D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_384470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9D1"/>
    <dbReference type="OrthoDB" id="2322999at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="207" mass="22663" checksum="FCEFBFE1069ED26E" modified="2020-06-17" version="1">MKTAFCTTARSYLGSIYNGLLDDSDQPPVSTKHITDLAAIFVRYNAYEVLGIQLIHGHFKILENSIMVGTNFENLALRRAKNTEIDDIDPANIYGHIFVLTADGLYAYEFQDGPLPDLSGVGQGFLPEFVNYIIRNNLTSLIGLQVLGCGDKSMSELILDQGTVMLDSSVVKNTLPTRVTVFNAGSPHPKLEIVKDLMLVLADVGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9J9</accession>
    <name>A0A6A6P9J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9J9"/>
    <dbReference type="OrthoDB" id="3946642at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="322" mass="35021" checksum="7DEA33A9892B5A12" modified="2020-06-17" version="1">MSWSEEASSFTEVTATSAADIHNGTTPAAALTTVYTPDPECAEDSTWFFRDSCMPTGWVEYWDGPEVGYYSPGICPSGFTPACERPAATTDDYGPAIAPGETATVCCPFHFECVATYQSYCTSNTLTAYAVTTSTSSTELSSSGLPAGTKIGIGVTFAVVGTAFIAGLFFWWWRRHHRRRQGKPADNCMALGHVPGFDSGNQVAHTGYQPGHARYDSISDNSNRTGPITGAAIEADGIAISGPTRPPEGTNPAGPARRGRSIQEQKEQLRKRREMLQQLQNLEDERHRRVLEMQRIDDEIRLLEEEETRGAAGIVQGGNNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9V2</accession>
    <name>A0A6A6P9V2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exocyst complex component Sec3-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_168106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27109at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13315">
        <property type="entry name" value="PH_Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.90:FF:000003">
        <property type="entry name" value="Exocyst complex component Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028258">
        <property type="entry name" value="Sec3-PIP2_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048628">
        <property type="entry name" value="Sec3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019160">
        <property type="entry name" value="Sec3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15277">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20654">
        <property type="entry name" value="Sec3_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09763">
        <property type="entry name" value="Sec3_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01313">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec3 PIP2-binding N-terminal" evidence="6">
        <location>
            <begin position="93"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="695"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="776"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1442"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="576"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1592" mass="171858" checksum="9CE9889956BED8F1" modified="2020-06-17" version="1">MDGSGGPRPRNLAPVNGSAPRGPPPILSPANNGPGGASMTRAERFEDERKRIVESCFSKSENNQLVESYITHIRVIEDAGYPQAPPPPDSPASNKKARVIICAVRNTGRVRMHKGRENANGTFSIGKTWNLEDLTGISSFTGLNPTSVEESRHKEWAGLEGFMVTMNKPYYWQANTAKEKEFFIASLIKIYKKYTHGKLPELVGFSPHEMDAILAPSMQGQQRPPPPSAQGRPTPPGASRPFDQEPPPPRSAGGQPSPNRGPPPNSSPDLGGPPPLPGMRNRPLPGPDGRPQFPALPPRRPVTPGEDGRALPGQRSGSSQSAASGEPLPPRGPDGMRQARPRPPGFPSDPQMRQPASRENLRPGPAGAFPPPRLSPQSSMSEMERTGPRPGSAAGSSVSSRTGSQAPQGSPKRMPLPYRTDGNTSSTSLDRPNRVNGVPASDGPKDSFDGRPLTGQSTASSAYGTPRADESMNFEGRFGRAPPERRRPPLASATGSNMSRGNESNDEFGTPLTSPPPRRDDVRTGARPTPDSLRSGGPGSGSADSGYRQPEGYFPSSRPSESSSLRNGSRDNNDIPLSLRPGSGSRPSSASGATTPPAPQAAETPPAPVPAQVPAPAPGPAAVEPEEPKSKVEPEPDAVKSPGADSVKSEEEDFRPGLGPMFKKKATTEAANAFRKAATAYGAFKPRAGGAAERLFKAENKTTNEPDGITSVVPAPLRTEKSNDTPTTPADEEKPPTKELSPPSRVRPSISTDEVPAVTVSSPTTAGAVSAVGRTLEDKPLDPATQLAATSPPVPTEKPAPSAAEVSEARRQRRRSNQHAKYLTALGIDPGLLEGRGLEFETVLSDFGWSGPTSGGSGGGVGIGILHEKKVDVLEADLRREIAKVEAGSWLTALDHKDDRVDAVEKMLDKAITECDELEGLLTLYGVELSSLNDDIAYIEAQSQGLQVQTANQKLLQSELKNLLETISITSRQLEPLRRGSIGNAEGLENIEESLLLLYKAMITIDPALRQSNSDNSKLNGGGFDNSELSTLRALQEKKERYLNECAMFLERLKQFMDMTFGAAIMDAKDALTTYSSGQSGQSAFSRKLDVRTHDIARSGLWQYGPLMLFAKEIDIYSWESLIKMYQNRARVLYQEEFRDNVLAWKKNTRKPTGEEAELLFTTQEKESEGISGTARKLTVKRSQTLARSLRTATGEKSSPTEKSAGGKIHPFEAFAGVLEETTPLVFTEQNFIVDFFHATSAEDMDFADAVLAAPPESRKGTNVSAKKLFEPDRAMAKRVVEVMDDMFAFWPADLQSLVEWAIKSEPLQGVGILAALDRTMLSLEETNQDFLSRIMTTIHTRLAGMFSRFVDEQIRAIEDTKVKIKKRKGVIAFIKTFPPFSAAIEAMLPPAAEEGPERFETRAMIDEAYARVGKAMFESLKVIAKESPAVASQAATAATSGSVASTAATGGQGGAGDPSEDKEVLNYHILLIENMNHFVEEVDERGDAVLQDLRIRAREEMDEHLGLYVDAVIRRPLGKLLVSRRENLHLHFCSTVLFGVNSLTEIIGFPRVSRRPALVRHGGCRRHLAAVALTFDVPQAPHNELRGHVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAH7</accession>
    <name>A0A6A6PAH7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_314817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAH7"/>
    <dbReference type="OrthoDB" id="5273213at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="24"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="618" mass="68325" checksum="5E243F518B979796" modified="2020-06-17" version="1">MSSKFYLGQRLSYEGDLCTVRYIGNVAGIEGTWLGVEWDDVSRGKHAGEHNGINYFKCKQTGTPGSFIRPNRPHDQPRNFLQALKVKYASELEEVAHGVVEKAIRISGKEVEEVGFDKVRRQLADLHELRIVLLDEMRITAREQNDYASPKKDDEKGRSTLNEIRETCPNILELDISRNLFEKWGEVVSICEQLEHLGGLRVGENRFRDISLTDSDVAHCKHIFNKVKDLSLEVTLLDWNESVSLANLFPNITSLSLSGNQYTTLPLGYLSSPITVLTLQDNKFSTLTDLLPLTRLATLQRLILKQNKISDATKPEERDPTGSKNKLPIFPVSVTDVDLSHNAISTWCFIHALGEAFPGLTSLRVAHNPLYRDLRHPADDSRPLTADDGYMLTVARLPKLKSLNFSTITDKDRLNAESYYLSLIAAELSANPASSEPAILARHPRFAALCAEYGDPVVRREVGAFNPNSLAARLLRLRCRLGPSALAAKAAANVKGHNNGERFVVEVPRTFNVYGVLGLVGKRCGLPPMRLKLVWETGEWDYPVPAASSASAASEGSGGVAPAMLDWDSESEDGSIALVKVPREVHLVAGTRAVGTWVDGLEVNVRVEMLDRQLGNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB29</accession>
    <name>A0A6A6PB29_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_140469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB29"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="161" mass="17540" checksum="2D5A8982423572FF" modified="2020-06-17" version="1">MSWCRGSKAGGRSGATAMQLSGRKMDRVSFKTSQSDFPRTQAGIGEENSSNGNVVREDKKKSWVLWFADSAEDEAVTRYLWSAGNKAARDSRKSKETFAGRSGTEEEEQTMIDGESNSTSGNSWGERRRATREVLGRVFSRSPSWSAPGGWACAAGRGRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBL2</accession>
    <name>A0A6A6PBL2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">alkaline phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_331925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBL2"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF72">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025474204" description="alkaline phosphatase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="567"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="581"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="664" mass="72539" checksum="70E78A714AE20163" modified="2020-06-17" version="1">MKYALFAAAAAAFLRLVGAQTYQRLGACPGFGCLFPPDQADFLAGQYFDIRLEVHQPVNGSEATDLPLDEDFTFTVAKAGSAAVSGAEFFGIEEPELETWDFNWYEDLFAEDDDTPTLVNVASKAYRRVALYEPGEYVATLSYNNGSKTIANWLVRDMETTRKAKNVILFIGDGMTTNMITAARLIAHKQVNGKYMTKMMMDKFPVLGHQMTHSIDSFITDSANSATTLYSGHKTTVNALGVYADSSPDEFDDPKVETIAEIFKRIWGGAVGIISTAYIADATPAALTAHTRDRYQSGAIVDSFLHGNVNYTWSPWDGADVLFGGGAEYFFNSSLGGESYNDLDYYALFEEAGYSVVYDNSALETTPNDTKTLGIFTVDNMSKWLDRNVYTDNLLDQENAPDGSGGDAVDQPGLREMTTKAIDILSTLSPDEGFFLMVEAASIDKMMHALDYDRALGELLELDDSVKSAVDKLTALGSLEETLILVTADHGHGFDVMGSVDTMYLNRAATDRQKRNAIGTYKESGQSQYAISGNLTYGPGHHFPSAWDPRYTLFDGVGAFPDFRADYQVNKDGPREPATPLEDEEGEPIDEDDNYANPEDSPNGYLVNGTLPVRDDQGVHSLTDVPVFAMGPCQELFGGVYSATDVFFGMAECLGLAQTTAPDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBM5</accession>
    <name>A0A6A6PBM5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_278088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBM5"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08588">
        <property type="entry name" value="PI-PLCc_At5g67130_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF140">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025653220" evidence="1">
        <location>
            <begin position="23"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="469" mass="50514" checksum="A9473FE13F6B95A9" modified="2020-06-17" version="1">MLSHRISLLLLPVLSSLPRAHAQDPEDLTGLTLTGTITDGGDGDVIPTGTTVSYADLESTIVLSTATDGTLLGTTGALETSLADANGTDSDSTRTSSSSQELTFLVGGQNTATSISGNATASANATMTSSSTSTSPVPTNVRPCNNYPEFCFRKYSNITEVCAHNSPFVRQNNAASNQYYPVTDQLNDGIRMLQGQIHYVNETLLYCHTSCDLLNAGPMEDYLTTVADWVKTHPYDVITILLGNHDQVDVSLFTGPIQNAGLSRYLYTPPQIPMGLDDWPTLSDMILTQKRVVFFMDYKANQTKVPYILDEFSQLWETPFSPTDPDFPCTVQRPPDLSDEKARDRLYMANHNLNVEVSFSGETLLIPDTANIVDTNAVNGSSSLGAMTDECTANWGRPPNFLLVDYYSAGNGSVFEVAAQANNVSYDRECCGTSSGGVRAAVMPPLTGSHPKLAVVFVAAVVSMIACIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBP3</accession>
    <name>A0A6A6PBP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBP3"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018853">
        <property type="entry name" value="DUF2457"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10446">
        <property type="entry name" value="DUF2457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="823" mass="90502" checksum="D7BD76C6250DB1A5" modified="2020-06-17" version="1">MQPLVTAVESTLAASEEVVGDADEPPDEQTPRPSTSQPRLPSTDRFDKAAPAPQACKSSLLTQAIHTSESDAHEEEEPQVFRLPIRGMSTCSAWSNGSAASTAELTSDGGLTSPGTRTSTPSPPLPPASFRGLAPGFQKPEPEVRVAIHNEEHDVVPVPPTSHPAVPPSTRGETAVEAGLGRKRCITFACGKKEATKLASGSSASPEPSAAVTATKPAEPKEPSKRPCSLKFVCPTRNSSSNNSNPKESIAKPRSNGRLVSPPPPPRRLYVSPKVQNVRAHRDSDATVRNESPKGTRKTALLFRPRKYSDNYAELNKREATRFHEFASSEEEVDEWVQESTCHRMRLTVNDTLHIENKLRQLGEEAEEEAMEDEAIEEEEEAEEDEEDEDRDALDEEDVEEDEQASVEDDSDDGFHSDDEHGFASSDESDNDSDCNWWAPGRSTAATSTDHLDLIRNVPRGRSSASPSPVGSMSSACVSLKTHGVAKRRKSQPMQIRPITPDLPDSTDFVCGTLDEDRPLEEAYLSCLEQRRAAKHKVTPQDIDPTFPTSDPEMDEEDDEDDVPEAEESDHMFMMGQPDGDEENECPAAKPFKRSPRLSPKRMRSPPPPAKRCRSPPPAKRCRSPPPRRLFGLHSPKRMRSPPPAGRIRSPPPTRRTSFQRSPRVSNAAETYNPYVMQLGERPAAARGVASSLPRQRHMFPMGMMVVVVPEEGSNEDQSAQDQQQPAARSARGAIDIVKGLEKKRQLRREKLFQKHCWKVGNKDKERRVPPMPPGKGCERMREMGLGLAATHKGGKRPPGPLGPFEAVGEDAGERAQQHILSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCA7</accession>
    <name>A0A6A6PCA7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_368747</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCA7"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF1">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025470865" description="cellulase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="30"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="327" mass="36515" checksum="705545CD9AC08B85" modified="2020-06-17" version="1">MRFSVLATAAALAGFTAAQEDREFEFFCMNESGAEFGEDTLPGEYGTEFIWYDESTMQTFIDGGVNLFRLNFKMERLTPNQLTAAVDPGYMANLTSNVEFLTNQGVYAMIQPHNYGRFYENIITDVDGFGAWWATVAEPFADNEYVIFDVNNEFHDMDQNLVVQLNQAAIDAIRGAGATSQYITPEGNSWTGAWTWTSSGNSQTMGALTDPEDKLLYQMHQYLDSDGSGTHEECVSATIMSERLQAATQWLQSNGKRGFLGEFAAGPNDQCKQAINDGLSYLAANSDVWAGHCWWAAGPWWADYMYSIEPPSGTAYVEYFPILQNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCY1</accession>
    <name>A0A6A6PCY1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_1859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCY1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="194" mass="21923" checksum="EFBD8FD3A64DB6AC" modified="2020-06-17" version="1">MHIRQRFPRAQFQPPDGLFASLPPLTIVAPQLNALGTRILPVSWQSFSPRVARRRGGRIEPRTRPDPIIDRAERKLSDHRLTTGLPAPNQVRLRARTNRPCQTFQSQLPARGLIYVWSFLFQPAENLTPGCYSGCAAIRNCGTPWPPITPPTQPASRLLHDPVRPTIVYRFPIRLGRTRHVPQGVLPGPNHHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDY8</accession>
    <name>A0A6A6PDY8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDY8"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="551" mass="60118" checksum="2934E6925E8C00AE" modified="2020-06-17" version="1" fragment="single">SASLAMPTLPWSKSNRSQASVGSSSEHHSSAAAGMFGGAGTRPPATKRGPHSAEPAAADPHEASAQHQRHQHRFHHPDDQRPQHQQQQQQQQPQVYAQQPSSSLGRAVSQRQSAGIDPPPVNVAASMQMQPPTPGMQTFGANVVPQGAQGQPYRTVAQQDSEMGRATPPPTRPANDYSEDDINNMLKDHQTLREKYQKVKRYYFEKEAQVHQLQNTLANQRLSLSRTSLDDTEYSSRFSRLEGLISQLAFSIRKNWKTIPSWLNASVNKEAVSLGKQEMTAVGRAVISAWVSEEVFEKYFHPDLEPILSAQLKTIQINIRRFNPPLGSSEEEEGLSSKVVNWRLATLEGLQDKLRSQESTNNRHALMDSLSERLIDHMRTYLQEPTPSELEGGVKMIVELAVNINCHLPLESREVHIDYFFPGTMVVPELMKIESGIPALTNPTAAAHQPADDSGDAASIVSQDAADGKDSQPSVGAGGSQTSLTQQAQGQQGQPQQQGGQQSQAQQGQQPPGSSSGGKDDGMPPRVRLATGLALQVRGKGVLSKSPVYTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE15</accession>
    <name>A0A6A6PE15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_418162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE15"/>
    <dbReference type="OrthoDB" id="5431013at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF4">
        <property type="entry name" value="FUNGAL N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="72139" checksum="9F88A4F125733EEA" modified="2020-06-17" version="1">MAEIIGLVSAIAQIAGAGLRLSRELHQYADTVASADKRLREIALHVKLTSRVIDELGRVFSADRAARLVSKGAAEAADEAVRECAAIFDEMAGLLEKAKGRRFLFPFREGKMELLRKNLERLVSVLELLMQVVLHAEVISARTIAPEEDAFRHNQIRDLIQAKEDATRKYETEQKKYLLLLQQGTTTSRFTSGFGLPGQSSHAHDEPVGIDSRGNNELLSFASINNITPGNTTADTRPQSPLTSTQLAQCIVHIQVLLDQFQAFRDAFGCSANVSMMDGFHITGTYEKTRAALDSILLRQKKVSSTHTRYRAKATGSCYAGSPTPSQDGRSPPMPGPINWADASQANFSPMQVYHSPYHSPTIPEASGTGQYGAASPCGAASPYGAASPYGGASPWGGSATGGPASPRYQAASPYWSHAPPAPLEHPAAAADSPDYGPASPQASPASPGYAAASPEQAPASPGVLSSPNRQSPAVESHSPEHHPDPPPSSGAREERMRPQLFTPVPEVRGMLSAEACGPELYGGGTPTEGSIHDWHMFRATHETMGHSSSALSDEEKGKRDWASPTTEDGSPVANLNLTDAQKDKEVESLLREWTTLYTAGKTESDLPVSHGVSQLDAATEDDNVVRESSSTVHSWKRKQALDEEVVRSLTAGDGILGSPKAKRVRKAQSTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE98</accession>
    <name>A0A6A6PE98_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_274547</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE98"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23134">
        <property type="entry name" value="RING-HC_ITT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23820">
        <property type="entry name" value="RWD_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000416">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="14">
        <location>
            <begin position="7"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="185"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="309"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2462325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="501" mass="54879" checksum="D9CE7B0A7C4337AB" modified="2020-06-17" version="1" fragment="single">MDDEREEELSSITAIFPELAIDAHNPFEATIDLTVAPSTPLPARFCTAGKAASQLASALPTTAPPAAPPAAPLTHLLSYLPPLHLSIVLPDGYPSDRGPLFSLTTSPDWLPPAALDRLRDEGTLIWEEYGRGQVVFAYIDFLQQAAERGFDLMSSPEDVLELPPELEVPLLDHDKRAKKDKFDGETFDCGICLEPKKGAACHRMRGCGHVFCVGCLQDFYACCITEGDVANVRCLDPGCGKEEDGAGGDGHHGRRKRRSERTLSPAELLEIPLPRDAVRRYVDIKRKKKAEADKNTIYCPRKWCQAPARSGAKAAPSKKRKPHPAASGPENEDDDLLDDLSSDSDAESEPDTPPNEAVAPADGAKAAPRAPAIPKDRLFICSGCSYAFCRVCLSGWHGDFERCWPRSAAELTAEEAASRDYMRLHTSPCPTCAAPSQKTHGCNHMVCFQCRTHFCYLCTSWLDPENPYEHFNSKLRVPSCYMKLWELEEGDEGPRGGEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PER0</accession>
    <name>A0A6A6PER0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_276831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IWS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PER0"/>
    <dbReference type="OrthoDB" id="21124at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.10:FF:000003">
        <property type="entry name" value="Putative Transcription factor IWS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="8">
        <location>
            <begin position="325"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="459"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="499" mass="54178" checksum="8C2F5F802B43F195" modified="2020-06-17" version="1">MEDPSPPPSDVESLPAGNADPGDPLRPEVEEENATPTPPPGAPDQDMETTEPLPTANAEAASSDEDASRRKSAADDDEDADLGGGGSDDESALSDVDEDQFQDFNPEDVNIEDRPVAIDETNVALLGVHKRKRAAGAQADGTTGGGAGAAGEGTGEIRRKKKKGDKKGEKPKRKRRLQKDDGDNDLGGGGLEGEDGFEGGRKKRKSRLEGGGERRRKKAAPLEDDEMLSPEERRKRALDRAMDEALKNPNTRRRKKDGIDLEAMADAEIEDMRVRMTDAAKADADARAAGQPAMHKLKMLPEVVTLLNRNSLQSVLVDPDTNLLEAVRFFLEPLTDGSLPAYNIQRELFAALAKLPISKDALVASGIGKVTLFYTKSNRPEVSIKRQAEKLLGEWTRPILNRTSDFRKRNLPSQDGGLPHRPPKKAMTAAEIAAQQARERLLAKPNMNNRARVEGGVGSYSVVPKSNVPAYNPYARPPGARADDPLKKLRARQAPTKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PER9</accession>
    <name>A0A6A6PER9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_260798</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PER9"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF88">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN CTL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="513"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2462322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="706" mass="76750" checksum="0067ACB6BD65E2D8" modified="2020-06-17" version="1" fragment="single">SATDDFREEEEEREREVADYYALAKSRRQFGGSHLTESSEVDDDDDDDDDDAAGEGSRTDHGGIHEGNEGDEARAHGFGGARGIKSSWKGGKIGARGRTKGVEALDEREESDDDGKRDESVPASEKSAPSSKGKGKLVDVELESTMRDSMEELDRNDIENPDDNPPAFQKFRNPPRSPMRHAIIPEETDEETARRYPRPPSPDRESIPPGAEGPMEHPRHDAFWANLYWICLASLFATFFLVFLHTSTPSNKKPLGDTIYTTLHASFHLLSVYTLVSIIVALLWLAVLRAFVRPLVIMILVAVPILLLSFSLYPFISSFKGTWHGESVQDKAMRWLSFIPAILALLWTYTVWKGRRSLSKSTEILEFACKVLAQNPPLLFVGFATLMSVVVWSWMWTGMFTRVFLGGHLNAKNKFVIDVSTWWLGVFFVLVYLWTLAVLSAVQRCTTAATVSQWYFHRLAPTTPPSRVVVQASLAHATSTLFGTICLSTLLVLAVRLPLLVLPRRLAGLVTLAAYACVPTPIATLTNPLALTYAAVHSLPLAPAARALANMPFVSKLSPTTTLSPRAVFDYGAARAPHAKPPRPAHAASALVPYRLAKLLLHATRAVMALALGFGGWVSTARLLRVTAAAAAGGDAGPGPGPGYKGSLYAYVVGLLAAAIGWGVLGAMEGVLGGILDALVVCWASETGGRLAAEARYCREAGELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEZ7</accession>
    <name>A0A6A6PEZ7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_368429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEZ7"/>
    <dbReference type="OrthoDB" id="10251342at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000001">
        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="6">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2462370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="339" mass="39253" checksum="D26EFB95374081DD" modified="2020-06-17" version="1">MASDEIVWQVINQQFCSYKLKTTKDQTFCRNEYNVTGLCGRQACPLANSRYATVRAHPDTGALYLYIKTIERAHTPAKWWERVRLSRNYATALQQLDDRLAYWPKFLVHKCKQRLTRLTQVAIRAKRLAREEDRLGERLVPKLAPKVRRREATRERKAEAAAKVERAIERELVERLRSGAYGDRPLNVEEAVWKKVLKGLEREGDGMRDMDLDEGIEEEKEEVEEEWEKENGVGEVEYVSDVEESDDEDVADLEDWIGAESDEEGDEEPEDDEDEETGKLDKDMEDSTGEQKKSPATLKRKRPTTTRQNKPNKKGGKGPKRKIEYEIENEPPARQTLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKT7</accession>
    <name>A0A6A6NKT7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_359579</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKT7"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="222" mass="24758" checksum="3602ED42188D3BEC" modified="2020-06-17" version="1">MTLPAPTVPPTPTHLNPAALAAAPPPSFSLCPPPALALPGRIPAAPFHPHLLLDLHCFPLGTAPHGSAIMSFQDRAQHQISQLDKELGKYEVLNNFERQTSVPKVYVVLGLAALYFFLIFFNIAGEFLVNTAGFVLPAYYSLEALFTSQKADDSQWLTYWVTYAFLTVFESAVNAVYWFPFYYTFKFVLVLWMALPQTAGAQIVFRSLLQPLFARFFNASSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLC4</accession>
    <name>A0A6A6NLC4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_157248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLC4"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="307" mass="34503" checksum="02A8BA1ED2F631ED" modified="2020-06-17" version="1">MLKIRYSSRADFISLGAVGAVYKINDRIALKIPREADRNKFAIEIATYDTLERHRPPCPDIAQSFLRTPDANFLAFYSHGTLDKRIRSHQVRSNEVLGGRLLQVTELEPLNLVHQWAMELSSGAAWLESLGLAHADLRPPNLLLDGQDHLKIADFDCVEAIGTLASGGAPPWARFCGPEGGDESGTFGKNGARVEQFSIGSILYFMSRGYEPYDDGAMWPRGPEIVDLMMDMQFPPIGEMDVDMTIQRCWRGEYLMLKDLANDTKLLHGAFSLPRAASFDDQYCKHAREECRKLVESGLLRSFDRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLD2</accession>
    <name>A0A6A6NLD2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_388547</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLD2"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="35109" checksum="4EEEBA0B154DEBCF" modified="2020-06-17" version="1">MSRHWDYRILDAIKGDATHTSTVFKAEVVPHENVSNPPKWALIKTASPEDADATENLGCECTSYRLPGVSSAAWFREMYDVIDDMTIAVEWLDTTLAEVKYQPDMRTYALIKTFLKAALTSCVVLDGPRYHPLMNPDYKPANILLSGVKTSSITAKVGDLGLVFPASDRINVQPLAMRAPEVFLGQVCTEPSQVWAIAAMVLSWIKTGVLGKSDSPHPLVNAAWCMAKIKRLFPDWEIPTPEEVERPTLQATVKAARRMSREEEPILAILQKVEMPQQLRDLLRLMLVTNPDKRPSASTVLASAEFRAFEKLVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLS6</accession>
    <name>A0A6A6NLS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_358390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLS6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="174" mass="17726" checksum="8FD35ED6CC45EDA6" modified="2020-06-17" version="1">MPATRSRISAAYSAALKQPRPFSRMTRASSCSRSRSRAPLGPARPPPPYSSATSSSCSSSRPNGCVSRPAAAALPTRSATRSSPCLPPSPSFSSPPFTSFSSSASGSSIGPGSGSPPTALPPRARRKLPPLRRCLATRSCARLLWLVARRGTGGDGGASASVSATSSAVRCSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLS7</accession>
    <name>A0A6A6NLS7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Endoplasmic reticulum Oxidoreductin 1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_358450</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLS7"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025365397" evidence="20">
        <location>
            <begin position="22"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="528"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="107"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="443"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2452692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="631" mass="69287" checksum="D973DC17DDE3F2D4" modified="2020-06-17" version="1">MRPKAHVFYLAVFTLLRSCHASSGSSSRQSGAASSTKTRDPSPDVCAFEPGAIVSDACASYASLDALNEALHPYITSITQHTDFFSHYRLNLYHKACPFWSDDSGMCGNIACAVNTLDSEDDVPLVWRAQELGKLEGPTARHPGGHPPAGDRPLGGQLGEHVGESCVLESDDECDERDYCVPEDERASAKGDYVSLVDNPERFTGFAGEGSRQVWEAIYRENCFSKQPSAAADAQGMSGLSDARGPLGGAALNDFQAQAAQDLRNVMHSQRVQAGIQSAIAAGTPLSPAAAAAVDTLELDDGCIEKRVFHRVVSGMHASISTHLCYEHLNQTTGQWGPNLACYEKRLRGFPERVANMYFNYALVARAVGKLRRHVRDYEFCSADPAQDALTKRLVLSLAEAIPPGADIFDESVMFRSGDAVGLKDDFRSRFRNVSRIMDCVGCDKCRLWGKLQTAGYGTALKVLFEFDEEDSSRDPPLRRTELVALVNTFGRISHSLKAVKEFERLIAERDGEARGGAAAATAAAAATGLPGDESGGMAKSGGTVDDGLPEDFPRRRKKKPGEGQSFMEAFWEEWNLVWRTFGYVLRSWVELPGKFWRIAVVETSRLWDFWLGLPPRPRSWEWRVPGREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLZ9</accession>
    <name>A0A6A6NLZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_375391</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLZ9"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16473">
        <property type="entry name" value="RING-H2_RNF103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000539">
        <property type="entry name" value="Ring finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="273"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="502" mass="52795" checksum="94FB80A235D91818" modified="2020-06-17" version="1">MASATATELPPAQTSQGSDDHDSGPTSSPLLFFVALGFGVVFTNLWIIVGVKYCFRYNQRNRQARAALDGETIDLNAVPRPHRRRREKKLMTMEEVNERFPLTKYKTWKAGREQDGLPTAGGITTSPSRAPSVKDVDAVTATNETRRSGDTARPGTAHSSRDSDQGGTAEQPQPQPSQSTEQQGTEAGPKPEDKPEGEKPSTTAHLEKVQTAVSTIAEPNQQRNSTTTTTAAEQPAATQRQASTVTDGDETDDDDPIRTAAAPEMLGEPGDTCAICLETIEDDEDVRGLTCGHAFHASCVDPWLTSRRACCPLCKADYYVPKPRAENFDAALAAAAGVGPADPNAMPTGRRNPGGAGISVGGLRVNLPSPPQVWIGSRTGFSGVRPRMLWLVPSSASPASPAAARQSTGARSQAAVSSNNNYSLATPPPPSGQSANMTGAASGGNTASAPASQRQGRRARLFGLGVPRLPRMPFRGDRTGGASPGELEAGRATQRGATTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM72</accession>
    <name>A0A6A6NM72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_293988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM72"/>
    <dbReference type="OrthoDB" id="5336565at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057684">
        <property type="entry name" value="DUF7924"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25545">
        <property type="entry name" value="DUF7924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7924" evidence="2">
        <location>
            <begin position="245"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="475" mass="53143" checksum="4978B46C408DA0B7" modified="2020-06-17" version="1">MSELEASSQQRVPSEATQPEPKRRELGHHPNDVAPPAHYLDNLSKIWLTKEALTELDRRTRKVVSSSKSRPNPQRRRPLTRGFHRELNRNIRSTSTPASEFVKRCSLESLRRVKLSARQGGPDLLDLRGYPEPAHPSRYTMSSTQSNRRHKRGKRNSASTSRIYPTATSTAITKTTKSSGAYNPNFEQRMIDNRIYPDGYEYPDGRVPPVPGNWEAIQQMLVKRRPSLSPSVFPEEEYQEFKRANAQVSSENKATRNVIPMIQGITRDERSVGSGIPFTNLADIMRGKSHKAKPDVYYGARPEQLDPNVRTQLSASIVPSTTETCPLAPNFFVEAKRPSASAAVALNQACFAGAVGARGVHSLQTYGEDVPVYDNNGYTLSSTYHSGQLKIYAHHLSQPNGPGTDPEYYMNQLRAFAMTDNRKTLIEGITAFRNAEAWTEAQRNAAIAHANAIAESSHDHNGEDDDDEDDNEDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMF7</accession>
    <name>A0A6A6NMF7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_154005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMF7"/>
    <dbReference type="OrthoDB" id="5134445at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="36188" checksum="4F8820FF893BE759" modified="2020-06-17" version="1">MEPTMSRCPYLPEKTLPVQIDGQPSESLDVTIIKAFEPFTLSCALLVRLNWPMLRGEYVLKLFDRRYATQLRRDNQASAWTADIEVAYHALVESTDMASLFALYAQKETDYEWTPKAEAGWDSAHREAYLQFCCRKHFSTETLVYDQLRDLQGECIPHLAARILLKSPSSSGPTHEYLDCPGILLEYVQGFSLTDLDKFAPKAAWQQICDEAIRIINLIGGRGIRNEDVKTRSFIVRHHPSTNNQQTTRPNVVMIDFGSCVLRTKDQDDRDWREWKAMQDEEGAIGVVMERKLNGGFTYVRTAESERLMDEFMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMF8</accession>
    <name>A0A6A6NMF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMF8"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051616">
        <property type="entry name" value="Cul2-RING_E3_ligase_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46224">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46224:SF6">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="18971" checksum="B4EF0D711BC59F72" modified="2020-06-17" version="1">MVGKWGSALVAAAAYYPYERHDTMKLLIEAGADVNAQLQTGEYGTALIAAAIASIGHVWQLLENGADPNTMALVGQWGSALVAAAQQRQVESVELLIVAGADVNARMQQGEFRSALHAAVRMEVAYEYETEAELKGTILRRLIDAGADLDAETEDVRHEIEACLGGAVRTVGEATSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN22</accession>
    <name>A0A6A6NN22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_356675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN22"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025688088" evidence="1">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="12447" checksum="0A5D44254A821BC8" modified="2020-06-17" version="1">MSKKRTSLLMWAIIELDVSRCLHDVIAAVAAAAGCYCPSRCPFLSRPRRLTRLAVRDPRLQGILESVWTPALGPYLPARHWPSGPPRLAFPDQIAGGVKEALDGGLMWGGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNJ6</accession>
    <name>A0A6A6NNJ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MICOS complex subunit MIC10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_356886</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Mitochondrion inner membrane</location>
            <topology evidence="2 9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNJ6"/>
    <dbReference type="OrthoDB" id="1916310at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="10653" checksum="2D830F78B77DDE08" modified="2020-06-17" version="1">MSDTPSSTAPSTPATQPTSRPMSEALLNEKWDRCLSNLVVKSGLGLGFGVVFSLLLFKRRPWPAILGTGFGAGRAWEECDNSFKRAAGPSQEGLRVVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNQ8</accession>
    <name>A0A6A6NNQ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BAR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_147310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNQ8"/>
    <dbReference type="OrthoDB" id="2159336at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000048">
        <property type="entry name" value="BAR adaptor protein RVS167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000189">
        <property type="entry name" value="BAR adaptor protein RVS167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="8">
        <location>
            <begin position="17"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="369"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2452923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="429" mass="48624" checksum="C45C59807482D57F" modified="2020-06-17" version="1">MSWKGFQKGVVRAPQTVKQRFNIGENTKDPVYIDAERRFQELEKETKKLHDESKKYFDAINGMLSHQIEFSKACAEIYKPISGRMSDPDSFVQEGNPEGIKACEEYELIVRDLQGTLQPELEMIETRVIQPANELLDIIKVIRKAALKRDHKQLDYDRHRAALKKLQDKKEKTLKDEKALYKAENDVEMATEEYNYFNELLKDELPKLFKLEREFILPLFQSFYYMQLNVFYTLHERMQSIDIGYFDLTLDIEAAFEKKRGDIKDRTEQLTIVHFKATGGLKNRPSRYGGGKLALDNKPARRSTLDSTETPPPPYSPSPANNTLSPPLSATSIGRANSTGSSWGAAAKAKGAAPPPPKPKPSQLKGQATGVETVTALYDYEAQAEGDLSFTTGDVIEIVQRTDNDNEWWTGKVGGRQGQFPGNYVRLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPL0</accession>
    <name>A0A6A6NPL0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein of 70kDa MW N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_388013</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPL0"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000298">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="102"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2453629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="373" mass="41376" checksum="5DD415F428A0DBB3" modified="2020-06-17" version="1">MTDKLPPNLLALFQPRPPLRYLPPCDTAPEKRATHHITGVGQYLQALKEYPKEHPYTPTESWLQKKDREKLEKREALEKLLNEDIKTYNPKEDPNIRGDPFKTLFVSRLNYDVEVKDLEREFGRYGPIERIRIVGDTHANESKPLGKKKKKNKGYAFIVYEREKDMRAAYKDADGVRIKDRRVCVDVERGRTVSAWRPRRFGGGLGGRGYTKTTPARPVGPGGFGPPAGPGGFRGGFGGGFRGGRGGGFRGGFGGGDRFRGGPGPRGGVGYHANGAPEGAPSGPRGGRGGHGGYGGRDSHGGGYDKRHDDRGYYGRDRGGPSSSNREPLGERKSYRDRDREGGYGGRDNRDDHPRKRAYDGDGYDDPRSKRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPQ0</accession>
    <name>A0A6A6NPQ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_116870</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPQ0"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="9">
        <location>
            <begin position="5"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="10">
        <location>
            <begin position="171"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2453701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="306" mass="32957" checksum="537058D96C5B031E" modified="2020-06-17" version="1">MSLPTIGYIGLGNAGYPMAANLPRAGYTLVVRDADPEREKKFVHEFPSCRIAKPGKDAFNDCEVIITMLPNGKVVRDVVLGENGIGPALKAGTVIIDTSSSSPFDTRALGEELAAHKLLLVDSPITQEFLHAIHDAGATLMIGSDSEEAIQKAKPVLDAMSKYTFVMGRLGAGHAMKTLNNYVSVGSIIALCDALVAGQKFGLDPNVMLDVLNVGTGKNFSTAYSMKEEGLTRRFQTGYQLSLLVKDVKIAKEVIESTGFKTGFPDLALHDLSDGLKLVQDGACHTECLKSWESRAGVTLKRRERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPW6</accession>
    <name>A0A6A6NPW6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.205</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2'-O-ribose RNA methyltransferase TRM7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_292506</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42396"/>
            <dbReference type="Rhea" id="RHEA-COMP:10246"/>
            <dbReference type="Rhea" id="RHEA-COMP:10247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.205"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.205" evidence="7"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPW6"/>
    <dbReference type="OrthoDB" id="289250at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106340">
        <property type="term" value="F:tRNA (guanosine(34)-2'-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03162">
        <property type="entry name" value="RNA_methyltr_E_TRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028590">
        <property type="entry name" value="RNA_methyltr_E_TRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF12">
        <property type="entry name" value="TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="8">
        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2453766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="377" mass="41307" checksum="1C9CFADB37E5A4E2" modified="2020-06-17" version="1">MGRSSKDKRDAYYRLAKEQGWRARSAYKLLQLDEEFNLFEGVTRVVDLCAAPGSWSQVLSRVLIKGEKFGRAGWEEKQQQDMAAVLGVPKGKAPHEAAGSLTMEEGAKEPAEGRGKDIKIVAVDLQPMSPLEGITTLRADITHPSTVPLLLKALDPETFDPSSTSASHPVNLVLSDGAPDVTGLHDLDIYIQSQLLWAALNLALCVLKPGGKFVAKIFRGKDVDLLYAQLKVVFERVTVAKPRSSRASSIEAFIVCEGFYPPKGFIASLQNPTWTEELLTSKSSQAAKNNEGERQLRKDGITELHLPPDPCEARSARWIAPFLACGDLSAYDADATYHLPKDRKSLEPVQPPTAPPYKRALEMRRAAGGAYGKTKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPW7</accession>
    <name>A0A6A6NPW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_292479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPW7"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008265">
        <property type="term" value="F:molybdenum cofactor sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043545">
        <property type="term" value="P:molybdopterin cofactor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="37"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="531" mass="58461" checksum="CC8635404BE7E680" modified="2020-06-17" version="1">MTSKFEYSRSEHDTPLEYDQYISQMREKEFPMLNGKTYLDHAGTTLYSKSLIDNFSADLIANLYGNPHSNSTPSVVSGRRVDNVRARTLRFFNADPDHFDLVFVANATAAIKVVTDAFRDHQNRTSEKFWYGYHRDAHTSLVGVREISKNLHRCFKSDSEVESWIENSCPTGDGRVGLFAYPGQSNMTGRRLPLSWCQRIHSDSKRKRVYTLLDAAALATTAQLDFSDPAASPDFTALSFYKIFGFPDLGALIVRKSSGSILRQRRYFGGGTVDMVIALDDTWHAKRESLHEALEDGTLPFHSIIALDIAMATHQQLFGSMGRISSHTAFLIRTLHAAAVEMRHPNGAPLLAVYNDTAAVYGNAATQGATLAFNVLRTNGSVIGYGEVERAADTQGVFVRSGGLCNPGGVATHLAFSAKEMRAAYAAGHRCSQPHEIMMGRPTGVVRASLGAMSTLQDVTRLIEFLREEFTGITSSAECASEGSVTEVEQKVIGLTVKVEEAVKSQVLSKAKRWTRKMGRLVGPRNTTVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPZ2</accession>
    <name>A0A6A6NPZ2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_356535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPZ2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20379" checksum="FD3CD7F41BF31482" modified="2020-06-17" version="1">MIDEEANKLTDDIEVQASVCRSDLSRLSLAHGALRAEIHPIVWAQRHYPRLPVSELIHRLEVMITELMIATDITYALVGRLRKRGQTPLPVPSKWARSLEETSIWFAIGDTHQYATCVPHRPDGMYLRSGLNEHARPLEIDDDDDWETIEESEPGELSQVDEHPSIHNVRYMSSSMLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ36</accession>
    <name>A0A6A6NQ36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ36"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="224" mass="25042" checksum="EAF7A9D143F42E57" modified="2020-06-17" version="1">MLEDDFNQMWNVIQNYLSQLTFYLSICNTHFTSNTALASDSTEARDEQVSKARGAISSPPSTPGRLEMSESQFHTLMSQVQMLEDNLRTLPFRANGHETASPLQNNLATGNDQSTRKDEEHIEAPEDETQEPTSGLAPWFCKIAKVNDDNVDVIDAGEFLGNLTDPVDHVLEQSQSTPSSEGKGKREWDSETTSETSDEFFFNENDLCHATHLDEVPSDLSHEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQX7</accession>
    <name>A0A6A6NQX7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RanGTP-binding protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_387953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQX7"/>
    <dbReference type="OrthoDB" id="512915at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008812">
        <property type="entry name" value="Ran_GTP-bd-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010:SF2">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05508">
        <property type="entry name" value="Ran-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="725" mass="79140" checksum="3C448BDC7236DDD7" modified="2020-06-17" version="1">MDVLLNKFTQQAMNYAIRSGITITSGYAIRQCSRLLKSVEGNDKEELAALQLRLESKIRLIILISPSAARGNTSLESAVTLTKNIRWDIQNLGVRLARAVSDEQLQRKGRLNNRSITQRDLELKLIIADIKKLLTRIEDAVPLINLAITTSGVNLSTTLPSSVSPSRLLQASTFLTAGDTQYSMEPAAGSVQIGPPFVLSMYMLFSGHAFRPHEDETIRETTWKEVIHKAKVKLIRVPLDKLNDGAPENDENYGPNSVPSEGKAYEFAYQLLIIEDLEDDRVHTFDDEDQPQPGSFEDVALAGIREIIPIHEISKIFYADTGKILNIGADGETNNPVLLFKRDVNAIPPRRMMEQQNLEETDWYDEHPEEWDAEDEEGDNTPSDHEEDDDAAAIEAQFRRESSIPLPPDDAQPPENTPHHDPWRLPPDLDPEWIAFEVYVEDPDSDSELDANEPSPSSVAANIPSPPSQPSSSRAGSREQTSTLASAFAHLRINPFSPHSSPPAVTPSPTSSPQPRPSSPSPDTQLATSTNTNLSASTPNTIAPTLPPLRTSLSLLELLVRLTALQQFQQSSHLAITDELLNFFLAESATVGAGADADLRRRVRAHARRKVGFDPYDESPIKRRGEDGAAGPGTRSPRGPRDIDLDHDHDPDPGDHDAYYFDPHDGGFPGSSSGSGGGSSRRASIRRGGDTAGVRRGDHRGEQGPAGGVEAGAAAEESVGEDGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQZ9</accession>
    <name>A0A6A6NQZ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_416956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQZ9"/>
    <dbReference type="OrthoDB" id="1878542at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="445" mass="48473" checksum="408B644BD4F3AEAD" modified="2020-06-17" version="1">MHDSARNLKICIIGAGMGGLTTALALAKAGFQRIDVYEYASDLGFVGAGIQLAPNMARILDRLGVWADIEKEAVTLSETYIRQGSTDEALAHVNLDYVQATYGYPHMVGHRSSLAGSIFAGCQREPAISFHFSTNTENVSFFPKPSFTAVPRAEGAAPQRIEADVLLAADGVKSNTRVDMLRELGVTAQVEDSGQAAYRIMLTREQMSGDAELLALLDGDCATRWIGPKRHIIAYPVSGKAIYNISTAQPDVNFAAAPSASYTTRGSKAQMLQVFADFSPKVRRMLDLVPEGEVCEWRLRVHAPLPTWVRGCVALVGDACHPTLPHLAQGAAQAIEDGAVLGAVLRRLPDAEPRSINKALRIYEDVRKERAELLVELAAANGREMHLGEGKAKEERDRLFKALKEGKGGGQVPDKWADKEVQRMIYGHDCVKEAEAVFERSFAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR15</accession>
    <name>A0A6A6NR15_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_423800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR15"/>
    <dbReference type="OrthoDB" id="5382468at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12418">
        <property type="entry name" value="RRM_Aly_REF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF82">
        <property type="entry name" value="THO COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="105"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="410" mass="44001" checksum="45ED40A86F4B31E1" modified="2020-06-17" version="1">MDRSLDEVISERQRANNRGSRDRRRENWPRDGVRKSSQRDDSRNLDRDWVHDRYDEDSDSRRPRGSRFPRVERYSPSPEPYVSPSFPLHTRLFSVVLSNRAERGARIRVDNLHYDLTEDDLRELFTRIGPITNLALLYDRQDRSRGIAYVTYPYLSDARLAIREFDGANAHGQPIRLSLVASAASGSGGGAGGAGGDLIGGSARARPRPGRSLFDRIESPVPPAAAAGESGGDGGRRRRHRRSMSPPAAGTRRSDVSKPPPEHIDRYVPGGASDHDFEYDDGAAGGVRRRSPLPRRRGPRGGDGGGRRPGERRERSRNEGGGGGRRGGGGAAGGGARDEGGRGMVQGRPRKTAEELDAEMEDYWGGGGGGGDSSRDAKGADAGVNGGAGFGAGAGAGQVRAGDGDVDMIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR16</accession>
    <name>A0A6A6NR16_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR16"/>
    <dbReference type="OrthoDB" id="2103031at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="38343" checksum="64BEF0AEBDA0A306" modified="2020-06-17" version="1">MGWFWGSSTSSNPSDDPLQNLDPELRDFLRKESHLQQPSQQRPQKQKSAPPTAASPTTTSSPTSSAEATRSSTTDASQSPSHPPVPPQSLYQDGRYAHLWKTYRPLSSIESASLSEPDKLRRIMEAYNDRKSRIGEAALENCAIEQIALHDCYHNNGATIGQRLKLCTDERRKHDRCFTLQAKFLTALGYLAEGEKSEAEEERVQMHADRLYHRMLVQEGESKKALEEGRKTMGAKPILSGEQSAQSEAEAEAMLETQVARMPPNLQKAYRDGTKNAKSLAQKELELKLLQRRMNVDRSVSAEVEKVMKEEKRARDERRERGEERIGDRMRRWFGSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS18</accession>
    <name>A0A6A6NS18_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GPI transamidase subunit PIG-U family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_416875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS18"/>
    <dbReference type="OrthoDB" id="549017at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009600">
        <property type="entry name" value="PIG-U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06728">
        <property type="entry name" value="PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="47978" checksum="6E2EA69026CAA4CC" modified="2020-06-17" version="1">MDVDRRAALLFGAAAAVRLLLYITFPSLPDLLTGRVEISTPVTSFKRLQEGVFLYTHNVSPYDGGVFHQAPLLLPLFSLLPGPSSSHLPTAFLYTLLDLLSAHSLLQIAASGASTRTRLFTSPRADTRYSPLAVAAAFLFSPFTIVVCVGRPTSAFTNAFVLLATAQAVQGKGTTMVLALSAATYLALHPVLLLPPLLILCYDAQMGPWKPVSAKYQPRASGRAVSFTLQYSALFGLALSTLLFASNLILPANATPRSFLPATYGVHLLLPDLTPNVGLWWYFFIEMFDSFREFFLGVFWLHMASYCPGLCVRLRHQPLFVVATLCGIFAIFQPYPSVADAALYFALVPLFRHVFPLMRYTFFATATLLYATFLGPAFYHLWIYAGSGNANFFYAITLVWSLGLSVIVADLLYAVLRDEWEAERPEVRGKEAIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSH4</accession>
    <name>A0A6A6NSH4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_387480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSH4"/>
    <dbReference type="OrthoDB" id="5372935at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27502" checksum="CE2A2C3ACC6B6E17" modified="2020-06-17" version="1">MAADNSDAESSVAEDIPFSFFDLPAELRIRIYEMLLVQPKPIDLDPGNPSRLSPLILSLFLTSHRVHEEAYHVFYGRNTFRLFPLHGRFFHSRWPLLARLPRRYRAAITSVDVRLGPGWTAPPKGWRVNRRLGLADCVALRELKVFVEVDPSDDCFRDFRVSKSFYTHFCRDLLVGIMNQVPSIETVEFDAYPAVSRSAPLMSELLTQAKARQKRILWGPERGWKQDTVDSTVENGAVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSQ3</accession>
    <name>A0A6A6NSQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STB6-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_102213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSQ3"/>
    <dbReference type="OrthoDB" id="19806at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059025">
        <property type="entry name" value="STB6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25995">
        <property type="entry name" value="STB6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STB6-like N-terminal" evidence="2">
        <location>
            <begin position="63"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="871"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="877"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1087" mass="117359" checksum="C4C99C8E6F1ACE37" modified="2020-06-17" version="1">MSKRVSLDMDGEAGAPRRSMQSSRTRADSSAFVQTMVSTPESPADPKQQQQQQPFSPRRADRQRFVLTDPVAFRYLEEDPSVDVLARRETLRGYECYIVEQWACSRTHPTFVITTYTGDPTHSVKVGVLSVPTDGSAWSPRLRVYYKALSQYHARRKETPYGFLMITNLSGFPSSLSVVSVPDGDVKAHRELFVVNEDLKRLGCSGRVSLTLTPPSGATQAKFHQLYRTSDKIALNAAVVELVKLCQVALSLFDKLDALYADGLLCDITEKAITDWWVEIGTDYYNMEPHDGILGPTTVAALLGLLIGARNRLNAYGAPVAKDVFDVEATKRGIAYFQKSQRLAKTRRLDRTTLDRLQRATAKAAAGEGQWSSMMPRAVKSTVAELSGKGGEMVMEMMNAGRDKAGIADVETVDIERFAQLVYGERMKWLWAGKPRKSGFASATGVGTGTGSEFLAARKYPGLDGEIGDGPYASGAHLVFREGEGEKEGTYAWERRRKESGADDREKESGAEEKERDSLRKKRYAASVSAASAAAAAGIPAAAATGKHGYETHVRSVSEQRQRQDAERDERDERDEQDDKDNERERDRDGRRDKEKDQGGRSKKTALRRRFKGAVGFRGHQHGKHSKDASASGLHDIGNEGSEASGLQRMDTVGSVFTDAPQSPAIGAGPEDSILSPTSQQQDTSATTGGPDGAIPTKFTKVMTETPQASDSTLFRDLPPHPTTATTAEDATPPNASDSSRPPTAPSSVAGPSTSGDTAASRGQGPSGNARFIPDANADADFDDILPRVPIPAPPGVNPAKAVQRHVQAAAAAGTGPLLRRTVSATGWDEWYGEGRSEERWGRRLSFSVAEEAVLRWADIGLGEDEAVAAEADDDAGSAASANAVAEKQEGSGAGDSATKAEKAKKDAAIRLALTRLGDRQSLRLRGSLAQLSVSLAPHLAALLAQTSELADQASRDAIDLSSIYTARLQAFHTAEGDAVALLGRERDGANEAVRELEGLSAKLEYEVEGLRGKVEDVEAGVEELERGVRTVEGKVGEVVGEVRGARNGKEKRRNRNGNANMERGAEEREGWLHWGMRMLTGVGHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSR9</accession>
    <name>A0A6A6NSR9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_365808</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSR9"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="10">
        <location>
            <begin position="52"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="11">
        <location>
            <begin position="227"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2454769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="29887" checksum="4124B84868DF5AE4" modified="2020-06-17" version="1">MPRPEDSLPPDLYYNDTTSAQYTTSSRIQSIQAQMTHRALSLLNLSAPSLILDVGCGSGLSGSILSSVPGSAGGPHTWIGLDISASMLGVALEREAEGDLFLADAGQGVPFRPGTFDAAISISAVQWLCNVESGTESAEGRLNRFFSGLYAALRRGGRAVCQFYPRDDRQKDLICGAAKRAGFGAGLLEDGVGTKQEKKYLVLTVGGGEIMGGDITGVVSGLEGVDVVDGRKGGKEGKRRNGKGVKSSKQWILQKKDRMERKGKVVKATSKYTGRKRKPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSX9</accession>
    <name>A0A6A6NSX9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CLPTM1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_353173</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSX9"/>
    <dbReference type="OrthoDB" id="378564at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="496"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="530"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="541" mass="61595" checksum="24B8BD0A9FD8C404" modified="2020-06-17" version="1">MLPAGTTRIVAERGFRLGNYSDTRTVEGSFEVPETVRRNGTLWTHFCVGLQGAELDPASPAWDTEKAYHFARPLNQYLPKKKVAKTRNLLAGTDEAEEEAEEEPQPEGPIIASYYHPNTTLSVVPDSGVLNFPQMHPAPRQFVQLERTGARDASGRDGWYYPIVYLNTFWQLREHMTELNSSVMELPYHISLSNLANWKFNLYASMDDGMRQNARAAAFGQGPAGGGDGSEMEEIKRVLIDSNVYLLGTTVVVSILHTVFEMLAFKNDVSHWRKKKDNVGTSVRTILANVVMQTIIFLYLLDNNENTSWMILFGQGVGIAIEAWKITKSVNVRVRPTAPGSSWPFPYAVVFEDKHVLSETERKTEEYDQEAFKWLYVVAVPLLLAYAGYSLVYETHKSWYSFIITTLVGSVYAYGFLMMVPSLYINYRLQSVAHMPAKAMMYKFLNTFIDDLFAFTIKMPTLHRLATLRDDVIFFVYLYQSWRYKVDYTRVNEFGQGGEDEEEVEKKDKAEAKTLKEKSDMDGVEATKASGKEKSEAKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT96</accession>
    <name>A0A6A6NT96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_290766</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat WDR59 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="311712at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049566">
        <property type="entry name" value="WDR59_RTC1-like_RING_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17120">
        <property type="entry name" value="zf-RING_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="119"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="RWD" evidence="6">
        <location>
            <begin position="488"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="607"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="700"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="993"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1096"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1268"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="734"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="772"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1048"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1064"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1115"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1276"/>
            <end position="1289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1360" mass="150886" checksum="82F52678C53EBEE1" modified="2020-06-17" version="1">MRLPADAFERRPTKAPASVFQSPTFDRDVSIRVNEAIGSASISPSGRDVVLASRHGLYIIDLDSPYSPPRHLPHRSPWEVADVQWSPHASTPSWIVSTSNQKALVWNVERADAPIHAVLHAHSRAITDINFSAHHPFELATCAVDSFVHCWDIRVPRPVLSFADWFAGATQVKWNRQDEHIIASSHDRVLRIWDTRKGAFPLRSIDAHSTKIYGVDWNRTDSRMVLTCSLDKTIKFWNYHDPDNRPERVIRTPFPVWRARHTPFGHGVLAMPQRGNYDLHLYDRRLEPGQAADAMVRPVHSFDAHKDQVKEFLWRSRGDIEGGNDNREFQLVSWGMDRDLHLHHIDPNILSAVGHERGKESLKGLNLTRKGAQYRTYRDEQANVSYGRQPVSQVPGLTAMFHAASTSVMAGRSPLPAVVSWNDGSYVASSPGMQTRSSSKKPLNPITWMKGVKIGKRDSDALGTIGSRSSMLLTDQSMVWENPDSLGDEITSVGERFKKVNFEEVDVDRRSITVTLNGPWGHENKPVFIRIELIFPDDYPRSAAPIHKIQKTTSAISDETLVKLDSEIRSITDMYRLRHRGCLEAIVSYLLGERDLHDSISWLSEEAGLGDETDDKGAESSSDEEDGVGADFDGGQTQDLEMSGRDMLRTVNANAQVPLPRECGATWANDGTLVCFFPPKPEPKPLFSLSAIKNSERFSNNQRIFPGAGRYGTDSPSRSNNPTLDVEEDDMEGSSEGSWTSSSSGSSSEDIGGLPGPFQPPTAWRGAAFRLQRSSQHSSADQGHRTTASKPKSVVSLRNMEHILPAKKTLAQNYQILGDGPSVCSHNEMIAREHGYEDLAEIWNFIRLILCNEVPLQVLEQSKSNDQILVLARRSLVSINRKDSGADLSFDHQMAVKDPKFKGRVKWGHHPFAGSWLVPALFDYFEARADVQMLAMLSCMLAEPPGRDKNPEMMMHFRQSEIPLALKAPAFSLDYYPSTEVAWGFVRGAPPGSAPPGGWDRRSLGSSPGWDSFTTNASKRLEAHGSASSFNGPWIGESPSGEPFPSNPLGTTPPTLSRTNTHRSSAAVSFSSSPEQHHHGRKPTNISSAWASLRQIPLGVSPSPPHNSKPRTSEGDLSTSAPTSGITWGSTTVYDGSTNAPQPHRSKHARRGYNYAHDTDLRDIEIKTNLRNQDQFDDEAGVDVPLLDPMQEGRYKAYREAYASLLSVWGFTIQRSEVLKFNGLVSHAYDVRPIDLAIDIASRESSQTHDIAAQELQPWRSISKAYANRVPSPGTHGDDQVLVGRKDQSDPLPPPELVVDVIERDSRPSCIMCWQRITGLYKSCLACGHITHTKCCQQWVAANDTGTCKTGCGCFCPADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTD6</accession>
    <name>A0A6A6NTD6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_380937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTD6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="565" mass="57921" checksum="5098E7495386D28F" modified="2020-06-17" version="1">MASVHAWLSGVSPSFSPSGLSPPRPSASAITSEAGSDNLTPRTGRHPSRRGVPLLSPQPRLSLRAFHAVIAPAGEAAPVAVGEAGAAPDDGAADAGAAVPDAAVIPNAALDGGVAPSVAPPAALASTRSRHPVGLETRPSVAGAGSKRSWSPSYGPHTSDELSSLPPPAKRPRTAAEARDNPPCTPYRLIREVGLVRPMELTKEERGRSPCPVSRYAPWQDEVSENGGERSEEQRGLAASTDVGMDDMEPSGEADEETVHQDEDAGDHTDVVVIRDDDVASVVTISSASTNGNKDSTVGDDEDAEDPTGEVCRDDASSVVFIASSSSLATADGEEASPSPAGVGASRAASNIRAVLEARAAAAADRTANRDLPGYRRAAALGDGRAQYERLCRSLEVSPGPEIDETTCARLEVDLYGGQEAIGEDACRTLDFGVPGLRNGREDVLGVVVGRGWGREDDNDDADDADDDAENDHEDAAAAATAAATAAASASAAASAAASTFINAAVSTTACGNVNAADVVANTAKSLPLHRIILTTSFISPHSCHLILIALCLRPDGHNLMITTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTV3</accession>
    <name>A0A6A6NTV3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_351829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTV3"/>
    <dbReference type="OrthoDB" id="525520at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2454874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="119" mass="13764" checksum="6C3D27833952780B" modified="2020-06-17" version="1">MVFILGINFSERKMVAKALQGFFGIGPSVSRTIMAHHHIHKTCRIGQLSQDQVVSMQSELSNMTIENNLRRKILDNIKRLRDIGAYRGRRHAMNLPVRGQRTRTQIKTATKLNRVERRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUA5</accession>
    <name>A0A6A6NUA5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUA5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="16575" checksum="80D8D9B7536AA32B" modified="2020-06-17" version="1">MARPVDPLDGTASGDRGTRRAGTRTFQTDVTRALARAQPNGFGARRSRQRREQGETRRANQPRAKSRGALKATLKAHPDGAREKTPPPNRLANRPSEQDAKPWSHTPNGPSASLGTSHPNPSLPTYLPTHLSRFCSGRQPTPSSAHFSPRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUQ4</accession>
    <name>A0A6A6NUQ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_306751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUQ4"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2455446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="568" mass="61731" checksum="8C6A198B688D8BDB" modified="2020-06-17" version="1">MTLHQFDYIFAIGTIFAFLDAWNIGANDVANSYATSVSSRSLTMKQAMLLASCTEFVGAMAVGARVSDTIRTKIIDPSLFDDDPAVLMLGMTCAVVASSIYLTVATRLGMPVSTTHSIMGGVIGMGVAAVGAENVSWGWDGVSQVFAAWAIAPCIAGAFGAIIFSLTKYGVMERKNPVRQAFYMIPGYFFLAAGLLAMLIVWKGASKKIDLTNAGIAGVVIGVAAATALLSVVFLLPYLYRKVLHDDWELKPYHIFLGPLLLRRPAPPSKPEGFVSIQDYYRGHLTKEELDMKRAEESPSNDPEKTGTTETITTKGAESDSDIITTQHRAQAPNVETSGKGKDCPEGKWYEPPVFFYLARKAIFRGVEKDIVGMQKKRDLLSGDIEGIHAKSKHYDNNAEYMYSFLQVLTAATASFTHGANDIANAIGPYATIFLIWHKGTQESKTPVPDWILAFGGIGIIVGLWTYGYNIMRNLGNRLTLMSPSRGFAMEMGSAITVIMATRLKLPISTTQCITGGIVGVGLCTGSWRSINWRMVAWIYFGWIITLPVAGIISGCLMGIVLNAPRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVB3</accession>
    <name>A0A6A6NVB3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein TOM13-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVB3"/>
    <dbReference type="OrthoDB" id="5529571at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="143" mass="15252" checksum="D3A1F1254EC43400" modified="2020-06-17" version="1">MTDSTPPTNLSSSGVTIPSDSENYSANNELSSSPSHVAEPDSSSPPDSGSDPARPTPPVVLYSPPTIWGLVRGAAINLLLPFVNGLMLGFGELIAHEVAFRLGWEGTKVFPIRRREGTRQRARPAGPGIEVREDADARGREDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVE8</accession>
    <name>A0A6A6NVE8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_70459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVE8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="201" mass="21781" checksum="BB9C0422D91D4326" modified="2020-06-17" version="1">MDDLVDDLVDSKIVGFMLGKLVVASLPHAKVGLIKVQNLLQAGSSRGPKGTSDVFANQCNRKWRPDQKPGLELVSQCLLGVGCTDDPTRRVDKACITDSVLCLSPVRGRQKATRRSTDPDSACTYARLLWGCAVAATPCRTRSLAPWSADFERSGRRSTIEYLTRALLPECSPPKCLRNQTSSVPEVAYLIDSSRQAGCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVH8</accession>
    <name>A0A6A6NVH8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_386697</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVH8"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14004">
        <property type="entry name" value="STKc_PASK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000320">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000314">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057213">
        <property type="entry name" value="DUF7891"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25421">
        <property type="entry name" value="DUF7891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="987"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="86"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="354"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="514"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="889"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="938"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2455736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1254" mass="136010" checksum="FE2F3AA007773FAB" modified="2020-06-17" version="1">MGRVRTCCGVTGPGRCARQSTGSFAPPQSLAASQRRSPHPAPDVHIPKNKSTGNLLAQAAASPALTIDTRARLSLDASALDLERMARLVPRRPRTGTGGRAGRGRSGPPPAPPSPPSSASSPSPCRELTARCRSPIVPEHEHGLGASGLRRIRQQPPPRPPGTPGAFTAQPSRAGSLNLSLPPTRRPSASLPSGPGSPTLAFSEDLHRFPTESLHSFSFAHQSEDFIHNRQNVLKRSIDFMRDKLGWAASNPAIANAQARLSGDQEVQSMMELLSRANLIGQDALHAHGLGAMGPATGPADMSGENIFEKSFIARTESPKSMEDPESPATESAKGGTDELSIPDSRLELQLKLDSAVKREPPADVASDSSPPKRTGSSPPPAPRATLKRTFTDVDGLSLQNKLTDALAQPYLAGDLAQDGQIVPPSALPNVTTTFHSVPNSHTAGNAPHGHGSRWAPAAQAIFTTDAQPPWTITSANDLACLVFGVTRAEVRKLGILEVVREERRKWLEDKLRDPLSGTSKSKEPVSQSEKSSPTPTTSLAVGNGVTAKLLSKPPSRVAGRRPRGRSKTDDGSGAAFGSNKPVKGGLNHDKNKSRGVLLCGDVVPIQKRNGATGSASLWVKEKRGGLIWVLEEIAEDVVYIYLDEVGCVTKGQGAIEAIWGTERMRRGMDIKRLIPGIPRLEGTNTGALDYDKIRDLRTFTARTSNNISIPVTVELLSDEPGFRVSSFPHIAGIMVLSSSTLRITSSNTVFSSALFGQSSADGLHINELIPGLDKLLRIMTDEDKIQLVDGIVIPEHSFRRARALLALREGKTDAAAVFLRPSGLPARHRDGAEIMVDVQMRVVKSERSVLEEQAIDDADADGPTSSAQVVYALWITYSRQLHAANSGVGPVTPLTSRPGTPPHQPSPGQSAAAIRGGDGVADLTKDAHVSLLTQQLREAQQDSVPSAPVTPPREEEAPVRPSSPPQSATSTPIRRGHKSTKTINDFVVLEDMGQGAYGQVKLCRYKKNASNKVVIKYVTKRRILVDTWTRDRRLGTVPLEIHVLDYLRRDGLKHANIVEMSDFFEDDVNYYIEMVPHGLPGMDLFDYIELRVNMDEQECRKIFVQVAEAIWHLHTKAKVVHRDIKDENVILDGEGNIKLIDFGSAAYIKNGPFDVFVGTIDYAAPEVLAGKSYRGKEQDVWALGILLYTIVYKENPFYSIDEIMDHDLRVPYVMSEHNLDLIRMMLDRDVDQRITISQVLEHAWCAVDTSGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVL6</accession>
    <name>A0A6A6NVL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_289005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVL6"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF1">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="521" mass="55656" checksum="EB0DBD7236726DEE" modified="2020-06-17" version="1">MAGLSTIPSGAPGPANEDNENVAPSQQPPVAARSRGTTTTSTPAAHAAGSRDSSPEPSFTPTRVRRSSTVVSAASAASDIAAAGSRRLRSASLRLVESDAPLGMWAATGAAASKAPGLGDIRRGSFAREGWSGEGQLGERERERRASGGEASAEAEGRRRWRRRTSSGETRSGDGQGSGWRARRLSGRSGSSAAADAPVQPSVTSGTPNADGYIPPPKLPWTSSTAIGLRAFWRWFLTPLGFAITVYGLNVVAWGGMLFLLLCNAAPAMCHPTCDDINSPRRIWIEIDSQILNALFCVTGFGLVPWRVRDWFWWGVYRVGLMGRSREKRMVGLRRLAGIHRGWFRLPGSDELGPGPTATPEIAGVPPPPPEAEDDRAALPIPASKAPDPPLTGVRAPPTAPWKMDFVVWCNMGNTFLQAVLSAFMWGFDRYERPSWSTGLFVCLACIAAGMGGIMMFVEGKKVKKIEGVPPNPEVVAKLAERAVDLEAQQAREKNEVVDGGKKRGLRARLAVVKSGESKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVR5</accession>
    <name>A0A6A6NVR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Succinate dehydrogenase C subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_365325</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome b560 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVR5"/>
    <dbReference type="OrthoDB" id="588261at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1300.10:FF:000008">
        <property type="entry name" value="Succinate dehydrogenase cytochrome b560 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018495">
        <property type="entry name" value="Succ_DH_cyt_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01000">
        <property type="entry name" value="SDH_CYT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01001">
        <property type="entry name" value="SDH_CYT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="20437" checksum="7A8C5944E86571F9" modified="2020-06-17" version="1">MLANRAVQTSMRRLAARQPGLMALGSQGKFAPPAIVALSQRRPVATERLSDSQAQNSILVNQRLKRPVAPHLSIYQPQITWYLSSAHRITGAILSGGFYIFGAAYLVAPLVGWHLESASLAAAVAAWPFAVKFAAKVFVSLPFTFHAYNGVRHLIWDTGSMMTNQKVIQSGWTVLGLTVASSLYLALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVS3</accession>
    <name>A0A6A6NVS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Catalase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVS3"/>
    <dbReference type="OrthoDB" id="2379805at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08153">
        <property type="entry name" value="srpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024168">
        <property type="entry name" value="Catalase_SrpA-type_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF62">
        <property type="entry name" value="CATALASE T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000296">
        <property type="entry name" value="SrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="316" mass="33852" checksum="0C5C526A5D865B43" modified="2020-06-17" version="1">MPLPDDPKLVQLGEDFIAQLQSMFGKHPGFRPAHAKGVMLTGTFTPTPAAATLSTAPHFNNPSTPVTARFSSSTGIPALPDTDANGNPRGLGLRFELGPHQHTDIIAHSTPAFPAKDGAEFLALFRAIAATGPGAPAPSPVEQHLAAHPWALKFVTAPKPSPASFATEAFYALNAFKLVSAGGKETFVRYSILPVAGQAHLDDAATAAMEPNYLYDEVPKRLAETGPFGYKIVAQVAADGDVTDDVTAEWPPEREVVELGTVMLEKVLEGYEKEQMHIIYDPIPRVQGIEPSADPLLEFRAAVYLISGRQRRAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVT2</accession>
    <name>A0A6A6NVT2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_387126</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVT2"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.20:FF:000001">
        <property type="entry name" value="DNA repair helicase rad15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.40:FF:000004">
        <property type="entry name" value="DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000381">
        <property type="entry name" value="TFIIH basal transcription factor complex helicase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.20">
        <property type="entry name" value="Bacterial XPD DNA helicase, FeS cluster domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042493">
        <property type="entry name" value="XPD_DNA_FeS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="20">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="255"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2455373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="795" mass="90653" checksum="9F891D764ECA4981" modified="2020-06-17" version="1">MKFFIDDLPVLFPYPRIYPEQYEYMCDIKKTLDAGGHCVLEMPSGTGKTVSLLSLIIAYQQHQPEKRKLIYCSRTMSEIEKALAELKALMKYRTDQLGYEEEFRGLGLTSRKNLCLHPSVKREKSGAVVDARCRSLTAGFVKEKKERGDDVEVCVYHDNLDLLEPHNLIPPGVWTLEGLIRYGERHTQCPYFTARRMMPFCNVIIYSYHYLLDPKIAERVSRELSKDCIVVFDEAHNIDNVCIESLSIDLTEDSLRKATRGVNNLDRRINEMKSTDAEKLQDEYSKLVEGLRAADEARQEDAFMSNPALPDDLLKEAVPGNIRRAEHFVSFLKRFIEYLKTRMKVLHVISETPPSFLQHLKELTFIEKKPLRFCAERLTSLVRTLELTNIEDFQPLQEVATFATLAATYDTGFVLILEPFESDTATVPNPILHFACLDAAIAIKPVFERFSSVIITSGTISPLEMYPKMLGFTTVIQESYTMTLARQSFLPLIVTRGADQSSITSGFAERSDPSVVRNYGSLLTEFCKLTPDGIVVFFPSYLYMESIISMWQGMGILDTVWKYKLILVETPDSQETSLALETYRTACNNGRGAVLLCVARGKVSEGIDFDHHYGRTVVCIGVPFQYTESRILKARLEFLRENYRIRENDFLSFDAMRHAAQCLGRVLRGKDDYGLMVLADRRFQRKRSQLPKWIQQAITDAECNLSTDQAVSKAKRFLRNMSSRFDPKAQEGISTWSLADLKAYQAKVETEQIRMLQAEQARLGMQNGGGPVGRVVEEDYAMDEAEEEAMRGLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW05</accession>
    <name>A0A6A6NW05_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_288763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW05"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="92" mass="10053" checksum="9B5AA6B9867A0BAF" modified="2020-06-17" version="1" fragment="single">AAQGCAYTHEKGILQGDMGCRNLLLGKNYNVKFCDFAGSSIDSCRPLCGPGSEFQRPTEDMGSISTSDELFALGSTIYEIWTARKPYQDDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW48</accession>
    <name>A0A6A6NW48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_324365</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW48"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="15">
        <location>
            <begin position="133"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="16">
        <location>
            <begin position="441"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="17">
        <location>
            <begin position="549"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2455697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="643" mass="73662" checksum="6B2CA84B59314D0C" modified="2020-06-17" version="1">MATEAQIAEWRARAEAFKPLNFKQLEGPMQELDAHLTLRSHIVGSDLTEADIIVWQALRENRVAHAHIKQGIMVNLSRWFRYVEEAHPSTVLPLREKKTKEKDEGKKKAKETKEDEDTNANYDIGLQEPEKGVVTRFPPEPSGYLHIGHAKAALLNDYFAHKKYKGTLLLRFDDTNPLKEKQEFQDAIVEDLRLMGITPDKVSHTSDYFQELYDLCVQMLQEGTAYADDTPQEKMREQRMDGIASYRRDAPPEDNLARFEEMNKGTPEGTRWFVRAKISVDDTNKALRDPVIYRCSPDQPHHRTGSTWKVYPTYDFCCPLVDAIEGVTHALRTTEYRDRDAQYQWMLKALRLRNVYNWDFARLNFVRTLLSKRKLTKLVDTGRVWGWDDPRMPTVRGVRRRGCTIPALQEFILKQGPSKNIVNLQWDTFWATNKKYIDPVAARYTAVAKDAMVRCSVRGEGLKNADGSPWSEQKDKHAKYTDLGKKTVVFGAEILVDQVDAASFAQDEEITLMNWGNAFVRGITKSGDTVECLDLELNLAGDFKKTKKKITWLAAKQGLVLVELVDFDFLITKDKLDDNDVLEDCLTPQTEFRTACVADENVAALRVDDIIQFDRKGYFRCDRAADVDNGVASVFFQIPTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW68</accession>
    <name>A0A6A6NW68_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_288611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW68"/>
    <dbReference type="OrthoDB" id="426001at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14521">
        <property type="entry name" value="DSP_fungal_SDP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="98"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="20221" checksum="B89846A5B48F7E33" modified="2020-06-17" version="1" fragment="single">MGFAEVPLEDEEDEQPNFDVPQSREDKPEAYPNGPIRIYESGVYLYYEPSAEVAADFDVIFNVASEVRNPFTDALSLASARMPEYIHMPWEHNTDIVPDLHKLVKVIDDRVQQGKKVLVHCQCGVSRSASLIVAYGLYKNAGLTVQEAYDAVKKRSKWIGPNMNLIMQLQEFRSSLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWB3</accession>
    <name>A0A6A6NWB3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutaminase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_65560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWB3"/>
    <dbReference type="OrthoDB" id="431715at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032515">
        <property type="entry name" value="DUF4964"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032514">
        <property type="entry name" value="GtaA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033433">
        <property type="entry name" value="GtaA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF1">
        <property type="entry name" value="GLUTAMINASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16334">
        <property type="entry name" value="DUF4964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17168">
        <property type="entry name" value="DUF5127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16335">
        <property type="entry name" value="GtaA_6_Hairpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025656290" description="Glutaminase A" evidence="1">
        <location>
            <begin position="17"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4964" evidence="2">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A N-terminal" evidence="4">
        <location>
            <begin position="108"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="3">
        <location>
            <begin position="417"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="840" mass="91673" checksum="01A42DD1FE75DC75" modified="2020-06-17" version="1">MYVLLCLLLQALGAAAQSGQPTYSPARPPAVPLAVHSPYTSAWSSTANGGTLNSNDVIFWTGQRLGWEGVITVDGVAYEWMGRGFQALPSMPSVKTAEPLAVAYDSQSSNFTFAAGPVEVTARFFSPVAPQDLCRTSVPLSYLEVSYAAADNATHDVQLYGDVDASWNNFAASANVDFALHADEAVVGDEGRISDAALFSWTYRLSQEYDFSEVNDFPQWGLFAYSTAPGEANSFTYQSGDAIDLRFNYVMDQVLTNEQSGSEIFAFSHDFGSSTSGSALYTVGTIQDPVINYLTSAGLEHLRPWWTTCYSSDPLDLIAFHYDDFSNALEMGAQWESRLKQDVDAYYKTSGGNFSSGGAPTVPPTWSNDTTNGTMSDYTYGVDQLGQHYMFDSGNAYGFLDLEGEAGIAIPDVSEASSYYAIVALSARQTLGAYVLTTPPELACSYGGTSFNMSEPFMFQKEISSNGNMNTVDVLYPAMPFFLYANPDMMRYSMNPLFLLQESGFYPKAYSMHDIGANFPNATSHVEGNDEAMPVEESGNMILMSYAYYKFSGDSVYLADHYDKLSQWANFLIEYTLIPFEQLSTDDFLGTLENQTNLAIKGIVGLEAMAGIARVVGNDQDAANFSSTSADYYDQWEDFAIAPSGEHTVLAYQWHSSWGLLYNSYPDKLLNLGVISQDVYDMQSAWYARVSQLFGLPLDNRHSLTKSDWELWTAATCAPATRRLIVDAVAYWLNNTSTDLPFTDLYDTIATGGYPQQSIRFIARPVAGGHFALLAMLKAGIDSDTGTGLGGFPLNSTEPVVESRPLPVLPAVTPSRVPSQVLASGSFTTSTSVIVTTTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NX48</accession>
    <name>A0A6A6NX48_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptide hydrolase</fullName>
            <ecNumber evidence="12">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_372686</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="12"/>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NX48"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05642">
        <property type="entry name" value="M28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 12 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="13">
        <location>
            <begin position="342"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="430" mass="46788" checksum="6AFFB47C586C2DA8" modified="2020-06-17" version="1">MVPQTPDAELQDLLAQVSVERIKANIEKLVSFGTRSTLSTQTDPERGIGAARDWIAEELRSYAEAADGRMSVEVPGYLQEVRSRVPFPVEVYNVQAKLEGGSEPDRVYVVTGHYDSRVSDVLNYEDDAPGANDDASGVAVSMELARILAPTHPKATLYFGAVAGEEQGLLGSNFMAETFANASVNVQAMFTNDIVGSSTGSRGEKDPYTIRLFAQGPPPTESAEQTELRLTLGLENDSPARELARFAHEVAANDATGMDVAVIYRLDRYLRGGDHRSFLESGYAAARFTEPNENFDHQHQDVRVENGTQYGDLLEFVDFEYVARVAKVNLATMWSLANAPGRATNVTIDTSDLTNNSTLSWNAPLDGDGEVAGYEIVWRSTNEPFWTHVVDIGMATTATVTLSKDNAIFGVRCVGTNGYKSPAVVPFPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXZ6</accession>
    <name>A0A6A6NXZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_380132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000022">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021905">
        <property type="entry name" value="DUF3517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12030">
        <property type="entry name" value="DUF3517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="1651"/>
            <end position="1992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2601"/>
            <end position="2622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2622" mass="296131" checksum="56DEF889E1721A05" modified="2020-06-17" version="1">MDAQDDVMGSDAARSSRAPSSEPSSLARRESMADACSSPTRKRPRLDSGDRAVRSMSADTVLASSSRTRPEEIQSPVSAGTHVEQEQTSAASPSAQAAASSSASTFPAQQHPPPSQVTINVRSQHQVSEPGQGDRPAPSSPPDRTCSPDHLPAGRDMECQPRAGSPQQGVARNQDVNLAESPNDDLPGSPSSVSMENNADSPVVEIEAGEPEDMDEDGADQVIQIDGEEDLLSLNLFQNFPFTEKMGTPLGAIAAVGKHFSEEPVDPNVVTEVTTWLEQQLSLLQNRKSEWPHFYKDNGVFWNEVAVAMIKLTRRRHPFGADLFDHAVESEDGVLQKLITVYVRLFARLVQIDADTLENADEDVDVDRELLLQKHWKVILNVFQCQFKEAPIWNQFQALFHLDIEELSLSFMSEFIRSPSDGLHHLARLAKASLRRAAVDQTGANNAILAGRLADVLCRRSYPGLGRIFAGWTSFPKDGLKFFRAVDELLQQSADKQAGQLPVEVSRELLSPLGECLLRITEQSDSFASELFNEYVGSTDLATYHFCPTVVRLAWKLRLLKKYITKGRMELRVWSVELMNNELLTLWRTFHQSPPGIGHPVMQYFASFLLEEHIIGSIIGVDSHPQLISRSSNIVGFLMVTHRYDDSMTDMIWQRGILSLDPRVVSATINMFSQIANLMDMHMLLYICGKLHDLPIEAYGPDVRFLSREIFERIRLSSSEFFRDDGRIKAYDLCIRLITEGCCGGTHPNASAAFEEGCRELRGLCDLSSLLEHRQFVYETCVREIKEGPSRAVGGRMRAIHIASERFVREDINLLARDLDLTRIAVEEMCSFVDSERPKPRPHPFTMCLGNPLTPRMGLLCVLIGEKPDSVPEELYDTLWEHLVGTKAIDSSARDQCWSHLAQLLRSQNKNQFLDRCISEHLPKLEPRFFTLPFFSFVQQAFEYQWRAAMIRSAGEEITEVPGVELLWHIIVTAHEGTIETHAAQFLAGVYLDPSKFQRTTLPKIETIHEDVVERCMRQLKDAFVRCRSLDAEAADAEDARMGSSTPDIELQQHRQRFGRTIVILTTLLELVRAKPEFAIQPRRLSRETAPSVVGESEPIAGDPIVIKYQAHNGKSTDMQSMTVGDLETLSDLQQRFASKTGFPKFTVIVGGRRWDLDHDETIRESQIATKGAFMIKRAADVPYAPRGSVSSAAGQSVIEREVLRHFDELYAFMDGDDCISEIVHKFLLIFPAHEKVREAVLREDVSVSAVFPPGQIFRTSYSIRALHSNLRQQIAQNTADEPFLAHGIRLCTAGLMSNELVSESLSGPRDVDISTVLIECLHAFLKECSFQDFPQSNFEDPVRFVRRVTAILNLAMMDPSKIKATYECYATLLDAALRDSRVWDAFTSSPEVVDIHRRLLLEDERLPLRVEIMKCIENFSKAYPDSAAVADEEFNIFYWRILSSILPHVQEHPRGSRQYFNIANAVFSKVRNQEESTLRAYLSDWGSMLLDHKHEEVVGRDEVDDVVLGLVKLLLSCVRSLKSFKKPLNCRDLMERIFVTFLFPPFSPQLGGRTVDDEDDEIIDDGAQGAAGRKAVGRDEVVEAKKAVPVLETYTRKELYDLTLALCEDLKAYRSLTNLMTQILPDYPRVVPDRFNVDRSKEFRCPNGYLGIRNLATTCYMNSLLTQLYMNLGFRTFVLSKNFVLSGESQTLLSETQRLFAYMQNSFDKATNANDFACTVRTIDNQQIDVQVQMDAEEFFNLVFDQWESQMLTTAAKNAFRSFYGGQTVNQIKSRECQHVSERTESFFAIQCDVKGKGNLTESLRSFVEGDVMEGENKYKCESCGGRFVNAVKRTCLKDVPDNLIFHLKRFDFDLATMMRSKINERFEFPMQIDLGPYMVDHLNDPEAHPPKQDVFVLVGVLVHSGTADSGHYYSFIRVRPTPGDATAHPGVPSPWMQFNDADVTPFDPNRIPDECFGGWVDTIEPQGADFHQQATLPKTSNAYMLFYQRASTLQQMPETTVLGADPTIPAVVPVPKEIGREIDADNERRLRQHCLFDPCYVPFVRQLVTHLRALTNNICTEDHHLEHAAIGIAIRNLHQIVSRTKDLPELFSTMELVRKWTFGGCIDCCVAVLRAFIFDPQFLRDLLLRAPLFRLRSEVSAFLVDALQHLRAMGPALYGVEQSPDSSPSDGDGEPFGVDQNGLFACVVERLGEYMDYLSFHRNWNEYFHTLARIAEFGNNEACYLIGHGFLKRCLSILVVHSPYSKQTRFEYHSLLKFMEKKKPQWEKLSELVSVLVRRLDLDPTPTGDDEQERAEIYDGISLPWSHTEAHLMLLWDPTERASVWLARIFDTWEPKFERFVPGEITTHLCRCGPSGKLYLNLRMTIRDGIDTLNANFVEPYVKAGVYFCLECPDLSHALEIIDTVIANAENSAAESQPLTGPMHLDFLDQIAGISNQNPQARSSPYAYCYRIMDRSPAWAGGLLMSTDERVRLETVFLLERLLFSHVPVAKHPEGSNEQRMDIYRVKVARALCNSLGLKLASAYDAEYPRRAMQPMADTLSKSIEFLRAAIDLGDDSLLPYGDERAMVDRSLMWLNNHHSDSSTTDAEGEMDKLEWQANEEELGQSEDWASDYSDDSNDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ00</accession>
    <name>A0A6A6NZ00_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-aminobutyrate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GABA aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Gamma-amino-N-butyrate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_286928</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="3"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ00"/>
    <dbReference type="OrthoDB" id="10260828at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000029">
        <property type="entry name" value="4-aminobutyrate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004631">
        <property type="entry name" value="4NH2But_aminotransferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00699">
        <property type="entry name" value="GABAtrns_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="517" mass="57051" checksum="F6515EB795D174D7" modified="2020-06-17" version="1">MQPAVKASTQLRPAAVAAFAAARRRPAAALPSPRLRCLATAAAASASERRATEHPLFPQEAKGPVVKMEIPGPNGKAAAKELEEVFDTRSLNMVADYSKSFGNYIADVDGNLLLDVYAQIASIPVGYNNPSLLEVARSPQMASAIVNRPALGNFPQHDWAEILSTGILKVAPRGLDQVFTAQSGSDANELAYKAAFMWKRRMERGGAHIDFTHDEISSAMKNQMPGAPQLSILSFSSAFHGRLFGSLSTTRSKPIHKLDIPAFNWPHAPFPRCKYPLDEHSADNAAEEARCLEETERLIKEWPLPPAAVVVEPIQSEGGDNHASPAFFRELRHLTRKHNVLLIVDEVQTGVGATGRFWAHEHWGLEDPPDMVTFSKKAQTAGYYFGNEDLRPNKPYRQFNTWMGDPARALLFRGIIDEIERLDLVSNTAATGEYVYEELRKLAGKYPGEIGNLRGKGQGTFIAWDSPRRDEVLKRAKSFGINVGGSGERAVRLRPMLIFQKHHADVLLDGLEKIFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ67</accession>
    <name>A0A6A6NZ67_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase/oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_346151</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ67"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF32">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE NM DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="27"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="155"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="269"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="465" mass="50842" checksum="1FACB46AFBF1C447" modified="2020-06-17" version="1">MAPSTSTPGPASSRIPVVARPFVGERAKETLDLVEKFVDEECIPADPVYAAQLGSTVEERFSAHPPVLEALKRRARELGLWNMFLPRNHFSEGAGFSNLEYGLMAEHLGRSRTASEATNCAAPDTGNMEVLAKYGSGAQKRQWLDPLLDGRVRSAFLMTEPDVASSDATNIQLQMRRDGDDWVLNGQKWWSSGAGDPRCKVYLVMGKSDPRHADPYRQQSVIIVPADTPGITIHRMLSVYGFDDAPHGHGHISFDNVRVPGSNMVLGPGRGFEIIQGRLGPGRIHHAMRSIGAAEKALELFLARINDPAKKPFGKHLSEHGVMLERVARSRIEIDAARLVVLNAAIKIDESDAKAALEEIAQAKVLVPTVALDVIDRAVQAYGAAGVSQETPLAQMYAVGRTMRIVDGPDEVHILQLGRNENKRGAAVRQKLAWQEMRSKELAKANGIELKDKLALNRVSGKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZF1</accession>
    <name>A0A6A6NZF1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8/S53 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_346660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZF1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="12"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2456978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="300" mass="30820" checksum="5068F5BD9E0994AB" modified="2020-06-17" version="1">MFTYTYEDTSLGAGVDIYVIDTGINIGHNEFGGRAEYGWSAYSSADDGNGHGTHCSGTAAGSSFGVSSNANLIAVRILDSSGSGTTSAVLGGLDYVVDAHNARKSQSGFIGSVASMSWGFTGRSTVVEEALTAMVDAGVHGAAAAGNSNTDACTMTPGSLGGDGPLVSVGASDIDDEIAYFSNTGPCVDVYAPGVDVLSAWRGSSSATNVISGTSMATPHIAGLMAYLLEQNGSMSPAQLKQMIVNMAIEGELQTRSDIVRGGELIIANNGVTTVQEVSIQSEAFPYEMEMVEGGNKLYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZR6</accession>
    <name>A0A6A6NZR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="6">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_345321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 8">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZR6"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="9">
        <location>
            <begin position="35"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6 7">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="48"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="328" mass="34555" checksum="3A80CF0548CE2950" modified="2020-06-17" version="1">MQTFRRPLSAALSAATRRQYATVSSAYSQTSMNLRITKDTRVIYQGFTGRQGTFHAEQAIEYGTNIVGGTNPKKAGQTHLGKPVFAKVADAVKEVGADASAIFVPPPLAAKSIEEAVTAEIPLVVCITEGIPQHDMVRITDMLKTQNKTRMVGPNCPGIIAPGQCKIGIMPGFIHKRGRVGIVSRSGTLTYEAVNQTTQAGLGQSLVVGIGGDPFSGTNFIDCLKLFLEDEETDGMIMIGEIGGSAEEDAAEFLKSNNTKNKPCVSFIAGISAPPGRRMGHAGAIVSGGKGDANSKITALEAAGVVVERSPALLGKTLHAEFVKQDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZX8</accession>
    <name>A0A6A6NZX8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">4-hydroxyphenylpyruvate dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_322048</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 4HPPD family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZX8"/>
    <dbReference type="OrthoDB" id="414569at2759"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00362"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000001">
        <property type="entry name" value="4-hydroxyphenylpyruvate dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000020">
        <property type="entry name" value="4-hydroxyphenylpyruvate dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959:SF1">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="VOC" evidence="13">
        <location>
            <begin position="40"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="13">
        <location>
            <begin position="215"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="416" mass="46474" checksum="746B8945AEB6F62C" modified="2020-06-17" version="1">MAPSAVSPTVIAANGAVVPLSETQNGTAPAVQPPQPNYHGYHHVTWWVGNAKQAASYYITRMGFRQLAYQGLETGSRSVASHVVQNGGVRFVFTSPVRASGRTSRRAEGDDPHIEEMYRHMEKHGDAVKDVAFEVDNVKAVYETAVANGAVGVEEPHSVKDEDGKVLIASVRTYGDTVHTFIQKDGYRGAFLPGFRLTKTAETLWSELAPISLEAIDHCVGNQDWDQMNEACEFYERCLGFHRFWSVDDKDICTDFSALRSVVMASANDVVKMPINEPAVGKKKSQIEEYVDFYNGPGVQHIALRTEDIISTVTNMKKLGVEFISVPETYYSSMRQRLKKSAVKVNEDFETIERLNILIDFDEGGYLLQLFTKPLLDRPTVFIEIIQRNNFSGFGAGNFKSLFEAIEREQEKRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P024</accession>
    <name>A0A6A6P024_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">RSC complex subunit Sth1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_35207</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17996">
        <property type="entry name" value="DEXHc_SMARCA2_SMARCA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.10:FF:000052">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit snf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000008">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit snf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000843">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit snf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000072">
        <property type="entry name" value="Putative chromatin structure-remodeling complex subunit snf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014978">
        <property type="entry name" value="Gln-Leu-Gln_QLQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029295">
        <property type="entry name" value="SnAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08880">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14619">
        <property type="entry name" value="SnAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00951">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01314">
        <property type="entry name" value="SnAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51666">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="QLQ" evidence="16">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="HSA" evidence="15">
        <location>
            <begin position="416"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="603"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="914"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="12">
        <location>
            <begin position="1322"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="528"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1214"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1408"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="539"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1247"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1422"/>
            <end position="1439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2457134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1447" mass="164504" checksum="128F9B433FD48688" modified="2020-06-17" version="1">MAGPAQPFPEPFSAGMAPDQSMAMPNMTREAMHDVFAKYQMMRQNGVNQNDPDFQRNRATLQAMMMSQQARVKQQQQQQQQQQQQQQQQQQLQNGTSHQPTLNGAKTAAGPVDTAAASATQAGPPQPSPAGSQTTPTHSAHPGQDGAPNSASSAGTLLNGSAFTKEQIATLRNQIGAFKRLSRNLPIPVNAQAQLFPSQQSRKEPTPAETVKAMAQAVDDVKKADKTAKSVEDAEIKDGKHQRKDSEKENDVGDSREPSAPVKQHRFETFTSPTAHLPKFMSYADHAWRDKRPIVPSLMPPGVDVEQTRLERENIIYNRVLARKAELERLPANIGVWDTRKSGSPGHDDGSLKLKALIEYKMLNLLPKQRALRENIGREMVYGDNLAMTANRGLYRRVKKQTLREARITEKLEKQQRDARESKEKKKHTDFLRSIATHAEDVRKAASVQRVRSQKLGRAMMTAHQNIEKEEQKRIERTARQRLQALKANDEETYLKLLGQAKDTRISHLLKQTDGFLKQLAASVKEQQRDAAERYGDGDLPEDDEDETDYATDEDEEGDGKRGRKVDYYEVAHRIKEDIGQQSSNLVGGTLKEYQLKGLQWMISLYNNNLNGILADEMGLGKTIQTISLITYLIEKKQQPGPYIVIVPLSTLTNWNNEFEKWAPSVSRIVYKGPPNARKQQQQQIRQGQFQVLLTTYEFVIKDRPILSKIKWLHMVVDEGHRMKNSQSKLSSTITQYYTTRYRLILTGTPLQNNLPELWSLLNFVLPTIFKSVKSFDEWFNTPFANTGGQDKMELSEEEQLLVIRRLHKVLRPFLLRRLKKDVEKDLPDKQERVIKCNFSALQAKLYKQLVSHNRLMVSDGKGGKTGMRGLSNMLMQLRKLCNHPFVYEQVEEQINPGQGTNDFIWRTAGKFELLDRVLPKFKATGHRVLIFFQMTQIMNIFEDFLRLRDLKYLRLDGSTKADDRSELLREFNAPNSPYFCFLLSTRAGGLGLNLQTADTVIIYDSDWNPHQDLQAQDRAHRIGQKNEVRILRLITSNSVEEKILERANFKLDMDGKVIQAGKFDNKSTNEERDAMLRVMLEAAEAAEALEQDEMDDDDLNLIMMRSDEELVTFQQMDADRAKHDQYGPGKKLPRLFSEQELPEIYLREDDPVAEEAVIEETYGRGARERTRVKYDDGLTEEQWLEAVDNDEDSIEAAIARKEAKMARRIAKKEKRERLAGAMGVSASPAVSRDSSESPAPPVVKEVKKRGRKPKADKRKADEAQLDAEVPQAQGPRKRGRQAKVLETLSTEERATLQRILDKVYDTLIDLEDGGDDAEGIPPRDIIGPFLELPDRTDYPDYYQFIKNPICMNQIKTKINKRQYQSLKQFRQDMGLLCQNCRTYNEDGSLLFKDANTIEETCLGKLREETEKHPDMQDFDDQGSSVNEARSTAPVSSVGTPLASGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I7</accession>
    <name>A0A6A6P0I7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras small GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_285612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0I7"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001015">
        <property type="entry name" value="ADP-ribosylation factor-like protein 8B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025558750" evidence="7">
        <location>
            <begin position="22"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="183" mass="20467" checksum="FF9DE5A1C411BC75" modified="2020-06-17" version="1">MAGFFRRIYDWLLGLFWATEMDITMIGLQNAGKTSLLRVLAGGEFTIDSIPTVGFNMKRVQKGHVTLKCWDLGGQPRFRAMWERYCRGVNAIVFIVDSADRDAIPVAREELMILLEKPALEGIPLLVLGNKSDLAGHMTVDELIDALNLKAVTHREVSCYGISAKEETNLDAVLQWLIARSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0Y0</accession>
    <name>A0A6A6P0Y0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS10m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S10, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial ribosomal small subunit protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_344998</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0Y0"/>
    <dbReference type="OrthoDB" id="366214at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000003">
        <property type="entry name" value="30S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="9">
        <location>
            <begin position="110"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00078476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2457123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="342" mass="39087" checksum="B62234D5BF85D803" modified="2020-06-17" version="1">MAAPAPVRPPFGALKRIKFSRPRLAVAIPQQRHKSTSSRQDQIESEVMAMDIEELAKKHNMKLPPNPEAARSMDAETESRLSALRLPRNVQAIYLRPLKREAPYGLPVCDLQLRSFSVRNLELFADFALRAAYYLKLPAKGPVPLPRITERWTVPRSNFVHKKSQENWERVTLRRLIQIQDGHPETVQLWLGFLRKWQYHGVGMKANVFEHEGLDVGKDLDVKAELAKGETADTWRRFGSDETKEMQDKVKELLESEPFRRVLASEGQIDRPNLVVKPDKTREMKDEVEEMQDQVDELQDMVKETRDVVKELLGSNPSGRASPGEEQIDRSNVEAPPGEKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P168</accession>
    <name>A0A6A6P168_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_385804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P168"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2457554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="318" mass="34605" checksum="E0B5BD15C3D9E7B6" modified="2020-06-17" version="1">MTAFGHDTEAKEVVSQFHDQIVGKTVVVTGASNQTLGSGTAISFARAKPANLILLARSESKVKPVIDEIKQMDSSINAVFVPVDLTDNDSVRKAAADISGLVDKIHFLINNAGVMAIPFSKNKHGIEMTLAANHVGHFLFTNLLMDKIIAAGAGARIVNLTSLGHFIGPFRFLDYNFADGKNYERWSAYGQSKTANVLFSVSLAQKLAKHGIQSFSVHPGSIYTTQLATHLQMEEFLEIEKVTKMNNGWGFSVSQPKSIEQGVSTTLRAAIDPNIAPQSGAYMSDCNIEPAAQYASIPEYARELWQLSEELVGQKFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P174</accession>
    <name>A0A6A6P174_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P174"/>
    <dbReference type="OrthoDB" id="4357141at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="214" mass="23638" checksum="D72D47095C8668BB" modified="2020-06-17" version="1">MTKNNILAGWAKTGLFPFNRDRVLRDITKPAAAPPIRTACGDAGLYPQDGVVQTPVTPVSLKGLTSLLNLFTQDPHDEVSKQRHMRLIQKLGNAAQTSFARHALGQDHIRFLYKVNNEAKARRKTKSDILGKARVMTYDDLEVARVKRAEKEAAKEAKGKRKRGRKRKSAAPETDAPEPDVPEPTARVVRMSRTQVAEDAIAPGTWGAPVAPTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P186</accession>
    <name>A0A6A6P186_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_371703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P186"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF14">
        <property type="entry name" value="CYTOCHROME B5 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="84" mass="9388" checksum="C19238D3A11050D5" modified="2020-06-17" version="1">MSQSFSTKDVADHSTVENGLYIIIDGEVYGMADFVDEHPGGSKILKRVGGKDASKQFWKYHNESVLKKYAPKLKIGKVKEEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1D4</accession>
    <name>A0A6A6P1D4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_303712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1D4"/>
    <dbReference type="OrthoDB" id="5407715at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05188">
        <property type="entry name" value="MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="2">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="1">
        <location>
            <begin position="195"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="39823" checksum="C0D0CC972D10F91D" modified="2020-06-17" version="1">MSPGLPSQHRALVFETVEAGFQLKTIPTLQPIPGSAVVRIAAAGVLSYSREIYNGQRHYEFPKPIVGGFSAVGHVAALGPDAASLRPGQLVYVDCVVRGRDDPSALFLSAIHEGFSDGSRRLMRDVWRDGPMAEFARAPLENCIALDEARLCRGLGYSPLDLMYMCYLLVPYGGLRDIGLEPGETVVVCPATGGFGGAGVQVAVAMGARVIAMGRNESELARLKEHVTKGTPGANVETVKITGDDDTDTAALQACGTIDAVLDISPPAAAKSTYLKSAIRALRRNGRCSMMGYVMDFMPGVKVMGSNITLKGKLMYEREDMLQFVKMLESGLFPKGKEFVDTKAFGLENWKEGFDVAAEYTGVGRSVVFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Q1</accession>
    <name>A0A6A6P1Q1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_371458</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Q1"/>
    <dbReference type="OrthoDB" id="9978460at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="4"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17648" checksum="51BA482FE34E014B" modified="2020-06-17" version="1">MSTGSRKRIVKELAECHADPPPGTKVQLIDESNVHTWEILMDGPENSVYAGGHFKLNLTLPKDYPFKPPTLNFATKIYHPNVSNDGKGSMCLGMLRSDEWKPPNRLLAVVNMARSLLLEPNPDDAVEPQLADQYKNDRAEFDKTARDWVRRYAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1S6</accession>
    <name>A0A6A6P1S6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_342954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1S6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="150" mass="16586" checksum="558719406CD73DA8" modified="2020-06-17" version="1">MVAAGNGDASCARFCPRQRSYEEFYDSERRCRDPGGVRTVLLSPRTELSAGREGRMVGAAVVVDRGPGLEAISARTRGLPWMVRCSSEIARGGAPSRRGQPVQTQRWCVAEGREDKRAWPAGLRAAAKRNDAVEGQARRCRRSVLRRERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1Y6</accession>
    <name>A0A6A6P1Y6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4 16">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDY21DRAFT_343436</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the NSE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4 16"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1Y6"/>
    <dbReference type="OrthoDB" id="185455at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="246"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="299"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF2458030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="336" mass="37620" checksum="3FBD8D9AF873BB3F" modified="2020-06-17" version="1">MSEEPDEAYDTTHRAFLQAFLARPAMTFEDAKPILARIFSIKEERSFLVNDVTEADFRNYVGTLNAALGPLDYEVRSALPQHGGRARVYALVNTTSDALTQLATAHSADEIAFIKRVLDAMFETHNRERAEIMAVRAMDAVQLHRPPLQGGGGGGGGATQRSSVPADESQAGLEGGQSQSVKAITMKQAEDLLASLKEEGWLERSRRGYYSLSPRALMELRNWLVDTYNDPPDEGNPNQWQRIKMCEACREIVTVGQRCSKRRCNCRLHNICVENFFRTQTERKCPVCKEDWTGRNFVGEKADPRVNNRSSGTSNSRRTPRTNNGDDATMLVEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P240</accession>
    <name>A0A6A6P240_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_320566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P240"/>
    <dbReference type="OrthoDB" id="5331848at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF146">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="41"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="394" mass="44260" checksum="FEE8EE71B2A9132D" modified="2020-06-17" version="1">MLAVLHPDPVEQAPEWEVQRAQKLVSLFWAKCIVATSIVALRFYSRRLMRATGADDWIMLFTMANREKNDTNVHSQVLFCVLTCMITYYVAIGGCLHMKYLTLQQGVEAVQFNWITQPVAIIQFGTGKASVGMLILRLLPRTALKKRWFIYFCIVSGLIVNSLCCVFTFVQCNPVEGLWDPKVPANCWKPDSQAAFAMFSGGEHRNINFTSLQNITANLDNSAWNVALDVIFALFPIAIVYKVKISLRQKLGLCAILGLGLLAAVFASIKIVHLKGLTERSDLNFETYNLWVWTGAEIFIIIVTASAPPLKPLVIRWADCFRRRMGWDTKTRGASSSQESQQREMALREGWREPGMGHLAHLEAGQRANGSVIDGQNEGEIRKTVEFDVMVGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P248</accession>
    <name>A0A6A6P248_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="6">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_371000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Nucleus</location>
            <location evidence="2 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UTP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P248"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="159"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="32809" checksum="0E5501FA88CD99B0" modified="2020-06-17" version="1">MSSMRNAVQRRNHRERAQPLERQKWGILEKHKDYALRAKDHKAKATKLKALRQKAADRNPDEFHFAMMSARTGAHGERLADRGNKALSEDVVRLLKTQDAGYIRTMLQRARREREKLEEGFMVEEKGEGVMGLKGVGGGKKKGKHTVFVGDVEEQKGFRPEEWFGTDKEGLSRSWNRPRRQQEDEIDEEDDDEDVAVAPQQQKSRKAIEAEYQQMKEERAMRKKLARERVGRLHRLQALRDQERQLEIAEQELEKQRARMSNSIGGVNKNGVKFKIRERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2V9</accession>
    <name>A0A6A6P2V9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_213269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2V9"/>
    <dbReference type="OrthoDB" id="73680at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13316">
        <property type="entry name" value="PH_Boi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11886">
        <property type="entry name" value="SH3_BOI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000082">
        <property type="entry name" value="Polarized growth protein boi2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035551">
        <property type="entry name" value="Boi1/2_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037370">
        <property type="entry name" value="Pleckstrin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12092:SF16">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12092">
        <property type="entry name" value="PLECKSTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="6">
        <location>
            <begin position="271"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="785"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="336"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="632"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="854"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1012"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="648"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="739"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="856"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1068" mass="114047" checksum="42966ED9E4D7DBDC" modified="2020-06-17" version="1">MAFRMQAQQSRPGDILQVVHDFVARSPDELSLSRGDKIELIERDDEFGDGWFLGKHLQNGNTGLFPEVYTRLLPTSALGSLPSKEKPQTSISDDTTTEQATADENVTKEDMNQVKTVEPSPAELEATLPAPAPPASSDRPATPPEETELDSSALATNQQSPVGRKTPQTASGGQPRMSLSSTAPRNISVAFSDAGGSPVMNETLSVINEHITDMNTPRHSFIANEKRAAAANNDSASEYSSHLDHRLSYINGHETDEEERGTHTELEVMTWSPLRVAEYLEDVGVDRRHCDVFRDQEISGDVLLGMDQSQLFMKEFDLGPVGPRLRIWQKIKALQSEVKSTGTPTRSVSDYSAADDASNDAVRNRATSVGTVLPRIPSLMEPPNSKTGSRLPPPRTSTQPQPSIPESASASSPSAPTHSPGLSTNSRPSAASVRSLNHNRRHSSADFGSNSKLDSIPDNAQQATPPPSVTSHQKKPSFDRNWTMTAMQQTPPTPARPPTSHGHTMSSDGTKFDSPSRDLSSLTAFNTQDLDRGYFSGGEIENRNRRNVLRKKDSPAHSRDSSYTSNSRARAANAFHRHSRIESNDSNRDSVAPIVSPAAKIYYSTGKMRGYRSGSGTDFTKSMVTKETTPTVTKLDYGDSPSIDAIATSPNPAGSETSSIGRASPSPALQTTQRPRAKGLRAISDAVTGGEKSLATSPHELLPSPIKESPVQSPVRTGSSTPSGTSKSFELENADLPKTSTGSSGGLTPTSGQGQAAASRRKNKKTTSAYTRGLQKRTPQEQMIGCDYSGWMKKKSSNLMTTWKTRLFVLRGRRLSYYYSEDDTEEKGLIDISSHRVLPADNEFLTSMHATITGVTTSPTSPQNTSTPTSASADSGAPAVTAKETKASPGVFIFKLVPPRSGLSKAVNFTKPTVHYFAVDNVQQGRLWMAALMKATIERDSSMKVSSTYQQKTISLEKAKAMRQRPPAFMGDEELAAGGVLVTKAAAAAAASSAEGLAISGLNGLPAVEEKKADAGEGDAGGGKTSGEVDAKETAGGGEDMSDVLTAPQTAAAADLALSGAAEKELAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Y9</accession>
    <name>A0A6A6P2Y9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor IID, 31kD subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_342198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Y9"/>
    <dbReference type="OrthoDB" id="341924at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="270" mass="28488" checksum="2E950586616C6D25" modified="2020-06-17" version="1">MPAPTGSFSDGPSAPNGVTTPIANANNSAGPQTSPPTHGTASNENHMNNQSGPRNEAGTGGASSQPGQNQSQAQSGPPQALQPLPAQPGTSLQDKGDSRRPRDSRLLHLVLAAMGVHSYQDRVPLMLLDFSYRYTAGVLGDAMALGDAANPGAQRAASAANAADQSLSMQAVKLAMRSRLGYQFGGPPSKEWMHDLASTKNRVALPRVDLSHGPRLPHERYCFTGTGWNIPEEWESEGEGEDADAAMADAEGEEDEFEDIMGRDAIMQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P354</accession>
    <name>A0A6A6P354_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_219578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P354"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16933" checksum="79573B8AC202FBED" modified="2020-06-17" version="1">MHLVFTPPRRHRHSARLSRSSSLLKAAWCTRRRTTRTAIYSSMWTSVRAGIGPLRSHNSVQHPSRLSSVTTFQLRRSCSYSKRSQAPGTGIGGTARAHVLRVDEVVPAVRVLGAKSPQCGNNARLFVASYRKRRPMVPLLYGDDFGRPFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3H2</accession>
    <name>A0A6A6P3H2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_269755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3H2"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000060">
        <property type="entry name" value="zinc finger protein 436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000176">
        <property type="entry name" value="zinc finger protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="9047" checksum="610825721D8E4A56" modified="2020-06-17" version="1" fragment="single">AAAANPWQHHHYISASSASAFPQSQDRYVCQTCSKTFSRPSSLRIHSHSHTGEKPFKCPHVGCGKAFSVRSNMKRHERGCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3S6</accession>
    <name>A0A6A6P3S6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_378415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3S6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="85" mass="9870" checksum="951B2D6C162019FB" modified="2020-06-17" version="1">MFLLRFSVSPGLVAVFVLLTFVCWYRLRAFISGKILQTICAFRSDFLGSVFVVWFDHLSFVHSIRPFLVSLLRLCRFCCLPFSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3X7</accession>
    <name>A0A6A6P3X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase III subunit RPC9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_341049</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC9 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3X7"/>
    <dbReference type="OrthoDB" id="1746530at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038846">
        <property type="entry name" value="RPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561">
        <property type="entry name" value="CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="156" mass="17344" checksum="76EACF14AEBBB384" modified="2020-06-17" version="1">MKILETQSAVLTNYEVQAHLQDMQARYQAQDEAQPNGKPKPSNLDAVMKDVITYLVDENSPLAAPSYYSEEAVKELYARLEKFNLTKAELLMILNLRPKFSALDPIIEEADVRFSEEQLQEIVDIIRDVLGGEDVPVEGYEPAENGDGGSGKKATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P412</accession>
    <name>A0A6A6P412_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_210836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P412"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058329">
        <property type="entry name" value="Arp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26053">
        <property type="entry name" value="DUF8016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025529793" evidence="1">
        <location>
            <begin position="38"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="Scytalone dehydratase-like protein Arp1 N-terminal" evidence="3">
        <location>
            <begin position="76"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="260"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="732" mass="78979" checksum="018067F9D3E4E275" modified="2020-06-17" version="1">MAAPRTSPARSSVSRSILTAFVASLSLLAATAPGSDAVPTDPALKKRADYVHIQDTPSGDALFSLGNTTYLANVQNPKAVLGGDCSAAAGGDLVPLAMVVIDDTTVTADAIQSVLASYAEGDDVYSDDFLAALLVKSGSADSGVSMDGSAVDFFDSIGLEYLFLDTAISCEGSGSFDTMYVDGLADSTLPPGPYAAIVSDESMALGMVYRLYEDTYNTFLYGAYDSNDGETTYMSLGAFYPKYWDPLIPVPSRIYYWDDDRPLAGQRVGIKDLYDIKGLITSGGSQAWAHIVDPAEDHAPSVQQIIDLGGVPVGKQKLAQFASGANPWDWYDEHYPFNPRGDGWLTCSASSSGGGCSIAAYDWLDYAIGSDTGSSMRRPAAVSGTYGQRPSQGMMSLEGVMPLGAATDTAGGKHSPSKLSIYPWQLLTNPESTVFSRDPYKWIKFSKNWYAPELHQSTEITGLPPLVVPDTDAFPKRILYPTDYLPLNNTRDAEPILQAFIDSMAAIFDMTVTEFNFTAFVGNASDPVASNFTTMREATGVINRRTQWEEVAKPLIEEWGARYDGRFPPIDPARRPGWVALLEDETGYSAADYADALVTKAQAVDWYETNLQFSTAESCSESVMLCDIGTGGLPSFRERELNESPDASYLAVTPEGAAVTCASICPIFGCADFTIPIGQVPYQSNVTFHEEMVPVTVNLIVKRGCDFVLYNMIERLADEGVLKTVMTGREAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P417</accession>
    <name>A0A6A6P417_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/beta knot methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_341301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P417"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047182">
        <property type="entry name" value="MRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103:SF1">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="23133" checksum="BE7D672FBA730941" modified="2020-06-17" version="1">MSRVSCLIYTQLFCPRGCKRRELIFNPLQLDPGNLGSIIRTAFFLGVDALFLNKKTCAPLTPTALKSSAGAAEALPIHAVDLAASFLDISRRAGWRVIAADWPSSSPTNSPSSSRTTFKTGPRFWDHSSSTAPALMLRSNAAGRKGGTGVVDKDFPTILILGGEGEGLRQGLKTRIDGYVGVSAGRDIQMIGLDSLNVGVAAGVVVWEVLRKMKGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P480</accession>
    <name>A0A6A6P480_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">V-type proton ATPase subunit d</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10 11">Vacuolar proton pump subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_338976</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P480"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016471">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000002">
        <property type="entry name" value="Vacuolar atp synthase subunit d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="211"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="211"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2458850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="255" mass="28691" checksum="F163F2FDE615EB04" modified="2020-06-17" version="1">MSGSGAREAVFPTRQSLGLMKSKLKGAQTGHDLLKRKSEALTKRFREITRRIDEAKRKMGRVMQVAAFSLAEVTYAVGGDIGYQVQESAKSARFRVRTTQENVSGVFLPAFESYQTEGNNDFSLTGLGKGGQQVQRCRETYARAVEALVELASLQTAFVTLDEVIKVVNRRVNAIEHVIIPRTENTIKYINSELDELDREEFYRLKKVSGKKERDAHAAELERAEDKDAAMRKEKASEAERHDMLGEEGNEDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4E2</accession>
    <name>A0A6A6P4E2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_341227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4E2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025553626" evidence="3">
        <location>
            <begin position="22"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="32967" checksum="26DB01EBD8106763" modified="2020-06-17" version="1">MGWVETCLIFWFACWGRSGSGCGMPRGHHRPTSTDPSRRQRAPRHGIPLLIAGFDRRPSGRSARPRRVRVGLDCPAPWPSRPSQSNSTQLNSMQAQAQAQTQQAPSLEPKRHLRPRMDRWMGGWTNESNHVQPLLRRASRCSIRPAPRQLRHPPERTAICRPRRDAIRRGETELRAERNTFPSLFFRRSIASFPDPRGRRGRGKTEAYSSSPATAERFVRVFTSSGVCAAVLRLAGRSSLLGWRRPVACFRREKGGSVSFCCAFLECFFLVFGLSFLTYFSFMSDGVVGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4K8</accession>
    <name>A0A6A6P4K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidative stress survival, Svf1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_197120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4K8"/>
    <dbReference type="OrthoDB" id="2590239at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.370.10">
        <property type="entry name" value="AttH-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023374">
        <property type="entry name" value="AttH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051385">
        <property type="entry name" value="Ceramide-binding_SVF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033394">
        <property type="entry name" value="Svf1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013931">
        <property type="entry name" value="Svf1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107:SF1">
        <property type="entry name" value="CERAMIDE-BINDING PROTEIN SVF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107">
        <property type="entry name" value="SVF1-LIKE PROTEIN YDR222W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08622">
        <property type="entry name" value="Svf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17187">
        <property type="entry name" value="Svf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Svf1-like N-terminal" evidence="4">
        <location>
            <begin position="55"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like C-terminal" evidence="5">
        <location>
            <begin position="219"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="383" mass="41842" checksum="A90A98D1AE99F82A" modified="2020-06-17" version="1">MFNWAKQQLANVAGTAEPIYGPEAIQPVSKQAENTPFTELKKDDMKWIVMDSTCVETQTFYFMSDAGPMGMAQIIYSNVAGIRTTAQFSAKIFYQDGGKTPHLWSTDALNNYGFSDDRFSFYADNVDFVLSDDGTSYTIKANVNPKCAVDVKVTLVEGVPGFMAGKNGTSAFGTNPQEPWGWMRHTFWPRCKVEGKFMTQNGDVDMTGRGLFIHALQGMKPHHAAARWNFANFHSPTYSAVMMEFTTPPSYGSTTVTVGAITTDAGLVLAGASPACSVVHEATTEDPENEWPEPTAATYKWTGKTVGEGKPASAVLDGSLGDRLDRVDVMAEVPRFVKQIVAGAAGTKPYIYQFAPKKTLKLKIGDEEKSEEGLLFTEATFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P503</accession>
    <name>A0A6A6P503_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P503"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="81" mass="8740" checksum="78C1764FCEA16380" modified="2020-06-17" version="1">MPGTREIDYDYKGGMYTDKCPTDQGLNDKQTPGWTGEPLFMAWHGKGTIAAVKPADVSRLENNSGKYGLLSGTIMDLGLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P551</accession>
    <name>A0A6A6P551_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_263655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P551"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="140" mass="15291" checksum="C5650FFD7B022448" modified="2020-06-17" version="1" fragment="single">AAAEGNYRLCQALLGLDARIEATDKNKATPLLLAVERNRPTVVSLLLRYGANPRVRDYAGWTLLHHAAHNNATDILEQLLYTADLAAPDVDATCPAKKTALHHCADLTLYDSAKVLLQHGADPNKLDIANRTPLWFAVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5M2</accession>
    <name>A0A6A6P5M2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5M2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="116" mass="12903" checksum="5CC689AABD372622" modified="2020-06-17" version="1">MGLVLSEGLRLCGWRPRARCRPPRSVIGWWAPLLLRLRSPRLWSWSWWWSFLVSVAVLLVLASLFCRAAAAQGRPAARGAVPPLDAMRSGAYLAGDVVMSFGTGAFQSYSRWDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P615</accession>
    <name>A0A6A6P615_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_377745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P615"/>
    <dbReference type="OrthoDB" id="28868at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.390">
        <property type="entry name" value="Hemimethylated DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011722">
        <property type="entry name" value="Hemimethylated_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036623">
        <property type="entry name" value="Hemimethylated_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02097">
        <property type="entry name" value="yccV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350:SF27">
        <property type="entry name" value="HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350">
        <property type="entry name" value="SI:DKEY-261L7.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08755">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00992">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141255">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="16"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="681" mass="77065" checksum="FABFF6D4403F68F7" modified="2020-06-17" version="1">MATPTPTTETSGSKSRDAFAVLPDELVHHILAYLSSDALAIASELNRRFHRLTLSPLLWRAHCLSYRYWHPRHRLSDKLAAPAGEVDWCALFAERQRIDRRVRFALDGILAGQQRRILRMRTLLLEGYDAKDELLRQCNVGKDEPGGGCCGTDECDDVLARRYYADAMLQHINRKLAVEEWERLGMARRKREKEVTLEGALAAYEMFILGQRGMDFDEISRRLDVLAEEFSEEHMGPNGGASLSTREIALKLVWFMREEKGFQGVRDEKTYRALKNSFIGIALEDENHEALPLITVAVFCSVARRVGLNARPCGFPYHIYAIVDSPPGRRLDDTLIAGEEEQRIDIGEGQQETATTATADPCGTTSVDEVARMYLDPFRTTEETPLSSLTSFLSTIGVARNTYASFLGPATNREMVRRTARNVMSSVQELRHLRFAARMPGAPGTGVDASAWVNIFPDVDTAFYAALWATFLLGMRPGQLSSTEQQDSGNDDGEDVPVANPHGQGRTYLPYLSQQFQTHFPEDVTLIEQHAMPHFVGLPQYEKLRETVQAIMLSDAMARPRIGRSKSSERSKNVRYRVGDLFRHKRYGYVGVITGWDPTCDHDESWIQAMDVDSLQRGRQQSFYHVLVEDKSNRYVAEENIDLVRTPPPQALLQVAGRHFKRWDKARGVFVSNVRDEYPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P656</accession>
    <name>A0A6A6P656_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="13">Aconitase</shortName>
            <ecNumber evidence="13">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_337910</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P656"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01584">
        <property type="entry name" value="AcnA_Mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000003">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1060.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="15">
        <location>
            <begin position="59"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="16">
        <location>
            <begin position="574"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2459307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="773" mass="84143" checksum="3FE482FE4C40BDB5" modified="2020-06-17" version="1">MQRFARLGRRAMATVSDSPLSRKVEMTNWEKGHYINYQKMSENLSVVRSRLNRPLTYAEKVLYSHLDDPHGQDIERGKSYLKLRPDRVACQDATAQMAILQFMSAGMPAVATPTTVHCDHLIEAQVGGEKDLARAQEINKEVYDFLSTSCAKYNIGFWKPGSGIIHQIILENYAFPGGLMIGTDSHTPNAGGLGMAAIGVGGADAVDVMANLPWELKAPKVIGVKLTGSMSGWTAPKDIILKVAGILTVKGGTGAIIEYHGPGTDSLSCTGMGTICNMGAEIGATTSIFPFNDRMYDYLVATKRKDIGDFSRAYAHELHEDEGAEYDQLIEINLSELEPHVNGPFTPDLATPISQFKEAVEANKWPEELKVGLIGSCTNSSYEDMTRAASICEDAMSHGLKAKSTFTVTPGSEQIRATIERDGQLKTFEEFGGMVLANACGPCIGQWDRRDVKKGEANSIISSYNRNFTGRNDANPATHAFVTSPDLVVAMTIAGTLKFNPLSDTLKGADGKEFKLSEPTGTGLPAKGYDPGRDTYQAPPADRESVSVAVSPTSDRLQILSPFEPWDGKDAMDMPILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAINSANGEANKVKNFTTGQWDAVPAVARDYKAKGIKWAVIGDWNYGEGSSREHAALEPRHLGGLAIITRSFARIHETNLKKQGMLPLTFADPADYDRIGPDDRVDLMCTQLAVGKPVTMRVHPADGSEPFEVQLQHTFNESQIEWFKNGSALNTMAKMAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P666</accession>
    <name>A0A6A6P666_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_197385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P666"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="172" mass="17975" checksum="80BE038719649EE3" modified="2020-06-17" version="1">MHAPPYYVLSPAASAPCCDNDSPAACGTAGSLRRQGCGASWSAARPLAGCSSAEIASPPKNAGFPCAVRVPRQRVISLDIRISARPSATPYWPLSGKLVLSGHHSQLACYASISAPRPSDDSSVAHASLVAGVLQEPPRFTLPCPKPGFVLNCFSADSATSTRISSLIWWKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6A9</accession>
    <name>A0A6A6P6A9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_190103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6A9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="213" mass="22717" checksum="4EA5301F5DAF78FA" modified="2020-06-17" version="1">MDPRSLPYPYILTCESFHHLSNSNKAVRLVSEGGPVSCVPGVRVQDPVPLVPMELDHSIEAHNLADGTDGVRSAETHVPMPEQPARGAAALATCGYINCSATGQRHETVTQGWTSREAGQRDCGGPGSAAAPSGRIDGGWAPAAHSRRPALAVFAFAVSRDWRSCRPPHRLIKAAQVLAAELYLPLLLSPPSFLPSFLLPHHNQTPAALFLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6C5</accession>
    <name>A0A6A6P6C5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_338502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6C5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="126" mass="13610" checksum="0A3A3B5866DE1322" modified="2020-06-17" version="1">MYPRRAESCARARSLFSLPLPTPPIPGAHLPGPGLWQLIAAPPLSPPNQLRSQSRRPTGAHAACANARSARLLVGCSSARVESWPIDPPRSPRALLPVRCCPSHPQRSCPERQFCSPSLLVPYSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6Q4</accession>
    <name>A0A6A6P6Q4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative amidoligase enzyme-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_362367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6Q4"/>
    <dbReference type="OrthoDB" id="412402at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2459676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="453" mass="51966" checksum="6D190224B4DC985D" modified="2020-06-17" version="1">MASHQKLLTGSKHPQRALEVLPVEPTEWFQLSVQSARSEHAQTTDPDDRELTFGFEIEFLLADIRYRNFDTLSQSLVTSVLCEIGEGWANKCANIEVQEADSTFWKIGHDNSVELTLTEEEMAAELGLIAKNCEISSRCFGYNEKGVKEEITAVLDALRQNFDQKTPGHPFRIIVNETCGVHVHIGTGKHEPTFDKSRFSLTAFERTIDEVHATNRTLQNNFLEPPSHRALNLCSDTGKKHPLEWVALIDGLDRQGLVEWAHSCSAFSDKLAYMFHVVADEEQCNGSGLEYKPTVEFRQHRGTMDPDEIFSWIDFCILLVKFAENTTPEEVNRLIHDHSLQPTFCFSDLLSMLGAEDRLIAYYREKCRPKTVVRERDNALSAETDFDKRDLIKLVEKKRFDQKNPVHVYERIVDKLRRNMYGHLSDPLRNALVESLQLAILAKRLVQYRTLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P736</accession>
    <name>A0A6A6P736_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_275119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P736"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16864" checksum="DB400102EFD0AC37" modified="2020-06-17" version="1" fragment="single">PFVIHRDLLTHYSPFFAAALKGNFAEAETQKVNLPDERVDTFEIFVEWLYSQRLDTTAPPQATGPFLKDGKPAFFSLLHLYSLADRLCIEDLRNDIVDAVATLAERANAVPTPSDTHLLYVAIRPSAPLRALVLDLFAFKKTDALLATHPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7L2</accession>
    <name>A0A6A6P7L2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_178398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7L2"/>
    <dbReference type="OrthoDB" id="3001700at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2459808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="104" mass="11088" checksum="7A93000D31D72493" modified="2020-06-17" version="1">MASTTAIVFSVLAGVIALLAAYVYLFGIPPELKREMQEQALKTMGENKASYIMKDQMDKIPDSDQQDVKELKGGLKNAVGGGLNNPLGKAGGDAADDLTRGMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7P4</accession>
    <name>A0A6A6P7P4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_369781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7P4"/>
    <dbReference type="OrthoDB" id="5394455at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="102" mass="11240" checksum="E10F6528166EE4E4" modified="2020-06-17" version="1">MRVAEILSDLTSLRVCDPSAAFALVSARPSPSRISAAEKQPDFSEQSELTTGAEDDDEDLRRAKDLVELHYKVKVGHADGRLDHELAEMRESVQKAVAKMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P856</accession>
    <name>A0A6A6P856_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Family 4 carbohydrate esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_370023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P856"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="25"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="313" mass="35991" checksum="FD138731C4C5F2D0" modified="2020-06-17" version="1">MGKKRVLVSYGVDIDAVAGWLGSYGGEDSTSDIARGLWAGTHGTRRLLKLFDKYGIKATWFIPGHTLETFPEECALVRDAGHEIGLHGYSHENPVDMSLEQQHDVLDKTFRLLTDFCGGKPPRGSVAPWWESSKETVELMLRYGVEYDHSFGHHDCQCYWLRTGDEWTKIDYSKNARDWMKPLVKGKETGMVEIPGSWYIDDLPPMMFMKNSPNSHGWVNPKDIEDIWIAHFDYYYREFDEFVFPMTIHPDVSGRPHVILMHERIIEHINKHEGIEWVTMEQMVDEFKSKSPAPQGAIMPAPRGEILKTPPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8S4</accession>
    <name>A0A6A6P8S4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_334860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8S4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="56" mass="5532" checksum="5167129984247188" modified="2020-06-17" version="1">MVMTGVGVSGVCDFCCGTGARDSRWAACGRGIGCYSHEALGGKRRGDSSGGCGSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9F4</accession>
    <name>A0A6A6P9F4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_168472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9F4"/>
    <dbReference type="OrthoDB" id="5244050at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="650"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="795" mass="85930" checksum="5DD3716DF15CE393" modified="2020-06-17" version="1">MGRSSKFSFPLPARWNHASRHALDDRAQDRTHPVSSPEIRQPRPAGGTKAERLLGTSSVHVSHHPPDPFEHRPTPQHQPSHMTVAASEASFDEDPDDLDMISAAAQDLAPPASPWRDLHARPSSNALGVAAQDPDQTSLHSHVLHHNGSSSTLRSHYDPKTAEREQAKAKRKKPTGLDLSKLFPKPRTGSRNLLSPTKLVSSPSVLSFASDGPGNHAVESKSDISVDQVSSRNPSRQETLDPSGSLPRSQHQPSQRPVYDNAKTNVRRPPRGIQHWFDGIDEDDDELIEDEEPEDGTRTLATVDTSGSTASSYGPNRSMMPLPARTTSLAPSRHHEEAHARQTYLDHLSPESPSFSHNKPPSLRSAPSRMTAASVRTKESKFSNTNLQDNSVLSFSSSEDEDDEPPQGSSVAIRDSMASTVEKGYHPTSKNANAVEINPRRSSKFATSQGRSASDSAHVAEKEQSNHLDQALLAMPQPQRANIQRLRRHSQRNMSCVLELDDSPPQTSKAMSTPTLGFPGYSSDRTGDRARRTSTRRPTPPRPKTTHSDNSVGDRRSRNMFHTSTLISSNSTSPTACSFPNRPHSVAVDKSESLGPNQTPGQMPPSPYRAPSARSFSPVGVSPSPAPTPTTATSRASPLPSPITPGRSFSAGVDGDVQVVGSDADWGASGGGGGGGDVDIVSVNAEKQNNDSERGQQTRRRTASSGIEDDIRASIQSGDFSGPANHHRNSTQPKQHRAKEKTQETQKVARRPPAPIATRRKSYGRTNPGQDFNSRGSVSEDVLAAWGSLGGWSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA62</accession>
    <name>A0A6A6PA62_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication protein A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_279217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA62"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A C-terminal" evidence="7">
        <location>
            <begin position="174"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="289" mass="30449" checksum="585147C98136EA75" modified="2020-06-17" version="1">MQAYDYGNQYTSYGGQGGHGGGGFMGGTQESPGSAGKGYSRETLRPVTIKQLLDVPPTTDDSFKLDGADVSALTFVGQIRNISSQATNVTYKMDDGTGIIETKLWRNVDAEAAAEMEGGDSRHSKPNVAENMYVRVLGRMRGFGNKNYVMASVVHPITDFNEIAFHLLEATVVHLHYTRGPPPSAGGGQAPGYGGGQQAAGAYGGGGMAPAGGAVAPAEDLSGLSQSARSVYKILNNELQTNEGLNVHDIAVKLKWDTNTVKKAGTELLDAGKIFSTIDEDTWAVLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBN9</accession>
    <name>A0A6A6PBN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_331854</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="2"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBN9"/>
    <dbReference type="OrthoDB" id="542135at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000016">
        <property type="entry name" value="Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006102">
        <property type="entry name" value="PRK08256.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
        <property type="entry name" value="NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="10">
        <location>
            <begin position="12"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="11">
        <location>
            <begin position="267"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2461338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="459" mass="49608" checksum="969A4D627B524A29" modified="2020-06-17" version="1">MVEGKGTEPCYVLGVGMTKFIKPRGKVDYTELGFEAGIKAMLDAHVNYDDVDQGVACYCYGDSTCGQRVFYQFGMTQIPIYNVNNNCSTGSTGLYMGRNMVRYGAADCVLVVGFEKMFPGSLQAFFQDRASPTGTSGLMMKEVRGASKAPGAAQMFGNAGREYMEKYGAKVEDFAEIARINHMHSAKNPYSQFHDVYTLDQIMKSPMLHEPLTKLQCCPTSDGATAAVLVSQSFLDARPELKSQAILIAGQMLATDSPNLFSRSSIDLVGYGMSQHAANVALAEANVKPADIKVCELHDCFSANEMVTLEALGLCEKGKAHEMVRRGDITYGGKVVVNPSGGLISKGHPLGATGIAQCAELVWQLRGWANNRLVDDCTVALQHNLGLGGAAVCTVYKRADGKATSKVLDAEVQKQTSLAYNPAVEAKGFTKEQALQVRSRKASSAWALQDTEQKVEARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBR3</accession>
    <name>A0A6A6PBR3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_383419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBR3"/>
    <dbReference type="OrthoDB" id="14339at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="551" mass="58185" checksum="FF0A9B3BDAB3BA87" modified="2020-06-17" version="1">MPNNSAPDATASAGHFFARKASASLFKSARAFSTPAPNPLPDPASSPPKRQKKDEELLHHQPDQTQGRSQASPPPSPPSPPPVVEPFTPPINTSPPSRSPTKPSPGGRRRRHSSRHSLSASVTDIGTSLRRSASLRSSSSSSHGASQPSTIPSILRVPPSTNASSSTTSTTASSGSSLSRPLLSLSFRRKRPLNGNSSSSSAAGVDPPQSDDITALPQTDRRPSTSHSMAVPLMHPPRRQGTAPHSNAGFGHGGLGPPAPIVSSSSASGHNPHAVFQHIHEMATKRISTLDYLRKAHEGRVYWFNTLHFSKADLSRLPSFDPRKLSRRATNYLLLGFSLPTILDLNSQSPNDYLRALNSLLAEFDAYQAAHPPDGATSSSLGRARIPQMFKRATAAAGSKSRRGSAATDLGLFLGGGAQNWGNDSVSDFGSNAFGISNASTATLSFPHDSGDHSGDDYAHLLTPSLPFDPDFFETFATLCDVLIDIYTRVLSLVATPETCGPGVGELFAKADARVRKLLVAGVVREFEDASRSGVKSEVAGVGRVVLGGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBS0</accession>
    <name>A0A6A6PBS0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Rhamnogalacturonate lyase</fullName>
            <ecNumber evidence="11">4.2.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_397549</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.</text>
            <dbReference type="EC" id="4.2.2.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the polysaccharide lyase 4 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.23" evidence="11"/>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBS0"/>
    <dbReference type="OrthoDB" id="114708at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102210">
        <property type="term" value="F:rhamnogalacturonan endolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10317">
        <property type="entry name" value="RGL4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10320">
        <property type="entry name" value="RGL4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029411">
        <property type="entry name" value="RG-lyase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016590">
        <property type="entry name" value="Rhamnogalacturonase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015364">
        <property type="entry name" value="RhgB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574:SF1">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14683">
        <property type="entry name" value="CBM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09284">
        <property type="entry name" value="RhgB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011794">
        <property type="entry name" value="Rhamnogalacturonase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025721343" description="Rhamnogalacturonate lyase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase B N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="15">
        <location>
            <begin position="280"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="14">
        <location>
            <begin position="364"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="49"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR011794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR011794-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2461299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="530" mass="56866" checksum="931D1BEA68D6061B" modified="2020-06-17" version="1">MLLLVFLVPIFAFTSDVLAAFGVSNVNGNYVIDAGSPEELLVTVNGQSCDIQSILFLGNELQSSTKGSHIASGLGTATVTAETLQGSSNYVKVTCETPSLTHFIVVREGESKLYLSTYVTEEPSVGELRFIARLDSRLLPYEYPFGECSTTADSDGTVEGSDVFVVDGETRSKFYSSERFIDDHVHCVHSDSLYACMLLPQKESSSGGPFFRDINSNNGGEMTALYFYMNSGHDQTEAYRMGLHGPYVLQLSTDVPSFDDQDVSWYEEVGVTGFVPDSERGQVTGRASGIPDGFETVLHWKNDEAQYWTYASPDGTFTSPLMKPGQYDMVLYQTEFAAATSSVRVAAAATTTADLASGIAPRDTVWQVGAWDGQPTRFGNAGRQLRMHPSDARMAPWAPATYAVGASALDAVPMALFADLTSPLTVSFSLPADLGPATLRVGTTLSYAGARPSVRVNDWQGEDPPAAQKLDSRGVTRGAYRGFGEVYDFDVPSGVLVAGQNTVSISALSGSSGSGFLSPNVVLDAIELFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC25</accession>
    <name>A0A6A6PC25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_82900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC25"/>
    <dbReference type="OrthoDB" id="5399555at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="17880" checksum="B08A4D1EAD6B649A" modified="2020-06-17" version="1">MDQLPDSARPILPSDSEPPSAQPTITTSSPTTPAPVHSAAGHSAADKRASTRLSTYSATPTLAPSIAPSHASETTMLSTSTAGGVGGNGADPRAQEIKSWNAGFARLEDKRLAQQRYALSSEKTDNMSKLALGAKVERALSRRMTGQDATFTRRGSRAATLAEKGIFGTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PC30</accession>
    <name>A0A6A6PC30_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_279037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. Reversibly leaves the enzyme after glucose depletion, causing the catalytic subcomplex V1 to detach from the V0 section.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PC30"/>
    <dbReference type="OrthoDB" id="6605928at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="390" mass="43800" checksum="8F7E2FBEC1A93B91" modified="2020-06-17" version="1">MSKPSAYLLVSLPTSISPSNDKDEALAALRATVTEDYGTTYPFSIPEFKIGTLDALVQQADDLSKLNAVCEGVVNKVGDSLRVLLEGDEDKISQQKTINDKPVDQYLRSFSWNKVKYRADKPIADLIDSLQKEVAGIDNDVKAKFNQYNQVKTSLAASQRKQTGNLSTRSLTSVVKPSLLVQDSEYLDTHLIAVPNLMTKDFIKSYETLAPMVVPRSSVQIAADDEFTLYGVTVFKKHAAEFVHKCREKRWTPRDYKYEEGGKEKEMREVERLSADERKLWGEALRLGRTGYSESAMIWVHVLALRVFVETVLRYGLPLDYVAGLVKTTPKLAKKAKSSLDVQYSYLGGNAFGRDKKGRVKQDDTTMDIQTMGGDTAEYTAYVYYEFEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD84</accession>
    <name>A0A6A6PD84_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_329995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD84"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2461916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="213" mass="21313" checksum="762DE6E221B2A233" modified="2020-06-17" version="1">MGGGGIGLVGRPPWGCGGGAPRPPPGGAYVYDGGRPSGLPWFIGSEVLEDEGLDGDEPGGGRCGGCGAGGVPAVAIRAFGGATTPGPACACCGGGAVAGTPGATTAAWMLAAECVDELDDLRLEPTRFLKRLCIDDMKFLGQVSGGVGAEGAFLGPGGARCGRQQKCWVVRRGVGGEGCEQGAAGGGRGRFWRGKRLIKRKGQSAGARRKKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDL7</accession>
    <name>A0A6A6PDL7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_388934</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDL7"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025712563" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="540" mass="59011" checksum="A5EF0184F4A21D3E" modified="2020-06-17" version="1">MALLICFALLILAFFRQIAFGQWDEFLVECGSSEPIHIPSDDFNAYIVSSTHVPANGLNEGGKWNTYPFCQVWAYIEYGSGDVVNFQLWLPDAEFYNGKYTAVGNGGMAGYISVWDMMTPLNSGFAVAGGDSGHKSSDNNGGSGAPGVYLPYLHDLDQTLAWIHNSIAIFTEAATFMISEYYAQEILYKYYVGCSTGGAQGFALAQYHPDLFDGIVAGCPGNWYSHLALSFLWNYQQASKLNAFMNQETLNFITTKAVEACDTIDGVQDGVIENPLNCDFDIEDLRCPPGVTVIPDAPDNSTVPSSSNSSGVACLSDAQVEATKGIYAGPLDLRSGFNTYPGFDIGSETQWLSQEGDLAKGFSIPILQNLVYRDLTYDASEFDWGNNIGDLDINAGLLIDAISPNLTEFRDAGGKMIVFQGWTDPYNAATWPIEHLEQIESHTGDTSSFFKLFMIPGGGHCGAASGYPQVPANYQTGVRLRDWVESGVEPQFVVSTSPPDGSVRTRMLCPWPKVAVYQGGDSESWESYSCGDWLHNGQYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE85</accession>
    <name>A0A6A6PE85_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_368363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE85"/>
    <dbReference type="OrthoDB" id="3899662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="42879" checksum="E74EFD7EED6D5448" modified="2020-06-17" version="1">MTSERSFFLELPTELRLHIYDYVLEDSNSITITSLRKTTATNSNSSSRPSTSNSTSSDSGLPANHVPVLRNRYDPELLSFTSPPSWEDYDRKRGNMHNDDAGDVLPAPFALLQTSRQVRDELCAHMGIRINKTTNKSSAGSDVGNNSNNGSGGNTSGGFHGLHLYVSYPYGVIALMQNHAALLHNIHYVHIAGAYETAHLKSCSQSSSFDSGYASSDSSASDSSSSSLRRLRTRRLAPRLSRRPSRLASPTRTAEDPYSHSFATVAAATSALTRLTRALLPSAPHPTFRQLSLRVYYAGERSYNALWDDSDAPSVVPLANACGGKVLLDVNRGVGATGMGVVIEPAPGARHLTVRWPKLPAGVKRAEGWVVEPAWGGVEKVGASRDSERRGRAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEG8</accession>
    <name>A0A6A6PEG8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_359848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEG8"/>
    <dbReference type="OrthoDB" id="414418at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF51">
        <property type="entry name" value="TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="34951" checksum="B2479068D534DCB8" modified="2020-06-17" version="1">MVLEAIYVCRHGYRSNWVVDSTTGSYSSMIRTPTGIAADPALASYGVDQANRLAEEIQRLEPPPDLLYSSPFYRCLQTLEPAAKALFERGKGEGVVRVENGLGEWYGTAHFTHPSPAPYDTLTTHFPSLLPSPRPPYPHPAPLLVPSSNGESIPTLHARVAYALSRIIAAADADPAQPKALLLCTHAATMIASGRVLTGRRPERWDEEDFRVGTCALSVFKRRGGEREVGEEKGNSEKLEEVGWEGVGVGGGWDCVRNGDCGFLSGGEERTWFFSNDESFLKNPNTYNDTLNAHFKPAGGEASSLKSEDDDKPDDKPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEV5</accession>
    <name>A0A6A6PEV5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEV5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="241" mass="27190" checksum="D0424B80AB2EF704" modified="2020-06-17" version="1">MHSILSSSNRQRLAKMISFTIKPKQSLAQRLLILIRRISVVLFGIGMASGAAVMSRYDTLKLFEPSGNRADNSTIIVPHMPCNRLPIQDVLSHLLNCPSTIFFRAYLPNFVQYPIPHDLLISTIVYAVCYAGFFWCFRYDKYQGYWYSGAILVSLFGKWTGLLQAHTFFIGLTPQLTALFIFLSAVQHRFIDSDERGKKTLAVEVQRVQASNIVDAEMGSADEKEALLNETGVDEKKLGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PF37</accession>
    <name>A0A6A6PF37_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_360337</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057962">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF15">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25603">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="IPT/TIG" evidence="5">
        <location>
            <begin position="913"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1105"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1138"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="222"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="472"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="652"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1241"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1332"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1521"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="85"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="652"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="713"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="775"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="805"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="850"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1258"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1344"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1525"/>
            <end position="1538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1698" mass="178421" checksum="E6FDB321A091211C" modified="2020-06-17" version="1">MATGGGDGGGNDDFFGQSMMMDPDENVSKWADEFNLFGNQVDGDPTDFAFFNDSPRPFPQDSASTPGFPASTPQASGLGSAQLVAQQQQPQQPQQPQQPQQQQQQQLPQRQNNQALQLRSQGSSSSPDSSGQDSASDASSSLRRKRKSSSQSSPMHLFDNMDHNAEGKAWTANPADLMGDMHGAGSGQDPSAPVPNRAPAGLERKFDSMQVNPQDVQVNNLFDFDGAGASPNYFDPSVGPGPAGSSSEQTMAPPNLHVNPTLVHRQHPKPTRHRPQKSFNDMPGPSRQQASFFFGESREPSPTSAGIIPSHEASPSGPYSGDSPEQLDFSMDAVGGGGGSGFTSAVNQNPSWPTEQGLDFASSPQLGLPNSTSSQPTAAGQLADPPIYLYIDPVNSKSRVETQIPIKLTMSRLPPGVSKMHFPRPSISKPKLLSKEPARSPDTLELYTSLVCASAMENQALKDRALRRARGEYVPPLESRRSSMEAQASEDGEDGGAGGRSAIREEDKPANGGEVRVCGNCIVRERKRAARKRVKSVDDENEWLSMEKKRNVVFNVNEYKDWAKPAPVKDANGAMVQEWPSSAMQIEAPMRIACYCRHHQEKKGFRVIFTLKDYEDKLVAQNMTQSILITDDHKTNGVPAVSSVPDMEYLQQMHSQKKNSQAQGSKNPAFAFGQQRNPHQPGFTSHRPYFSHSDLQSLRANPPNFYGNRNALGGQSPNMPLQAASTTMTPRNLSRQASPSISSGPNKRRKGSSSVHKMLSDLTMTRADNPPPSVSIPNTTSAPGNAYTPTTTSFGTAPSQPFVSPTTMPGGFNTGPPTPNGVTSGPVTPHPSRRSESMDNGYGFQIYHSAPSSAHQSRAPSPLSATRPPTNHSLFPPQPPQQHAQLGGPLMHPTGLPFDMNTAAMQSSTSAPPPQIHKVSPAEGPKAGGIEVTCLGSNFHRGLVVMFGELEATVTTFWGPTTLMALLPPSPDPGLVAVTLKDDNGSRHPQPNALGRGQPLTFRYLDDEEPQVMKLALQVLAHKQNGSSDSYREFAQSVIASMAPGQWGSSGGGMGGAGGGQMTGLQHMLAAAAAVNAEDVLLSCLNLIDMDDSPHQPRWNLRSRTGATMLSLACGLGYERLVAGLLARGANPDARDRGGFTPLMFAALRGRADIVRRLILKGADPMLRSLNGYLAADFAAAVGDDDVLAALRRVQFHRRTRSAGAASLRSGGGSRASSFASVRSGLGGWDAGLRLRLRRSVSPLGGGTRPGSSSAAGAEEEEEEDDDDIDGVLLSATEDEDEDEDEDAGSCAALDFEDGGAVAVRCSPVPPATPLWSRSRRGSKAFAVAAAAAAGVEDVPRSDEDADEDDDDEAEDGGSAAAALGAPADATATAVAAAARDSAAASLAAWRDHLAAQINSFHQSVGWAAAAVALPNLGSLPMPQMPQMPQLPPAVAALGRPQLPQIPAEYQAHPMVRRISSLVPQRGARSDFELTVRPGVAEGAGVAEGAGPAPAAVAVAPAAPLAEPDAGAGAPPAYHEIYPEGGSGGGSGGGGGGAAATADAPAPDKKRAAFAAAAEAVLDRRCAEAFGEGGGGGEDDVAAAAALAEGDEAAAAAAVDEAGGEQATRAVDVKIGPERDFPPQVRDRIRAARAQAVKSGPRDRRLFLLWIPLLLVVVGMMVKNAVPDVVAGARTVYEVGRRVVDGEGEGGVERLGCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLF8</accession>
    <name>A0A6A6NLF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_329083</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLF8"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000008">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000034">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="170"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="43927" checksum="7F07135477C347FD" modified="2020-06-17" version="1">MSSEADPERTAALEEYKRKLLESREWEAKLKALRLEIKGLQKDFDISEENIKALQSVGQIIGEVLKQLDEERFIVKASSGPRYVVGCRSKVDKAKLKQGTRVALDMTTLTIMRMLPREVDPLVYNMSLEDPGQVSFGGIGGLNEQIRELREVIELPLKNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAVASSLETNFLKVVSSAIVDKYIGESARLIREMFGYAKEHEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDYLGKTKIIMATNRPDTLDPALLRAGRLDRKIEIPLPNEVGRLEILKIHASGVSTEGDIDFESIVKMSDGFNGADLRNVVTEAGLFAIKDYREAISQDDLNKAVRKMAESKKLEGKLDYQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLR7</accession>
    <name>A0A6A6NLR7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLR7"/>
    <dbReference type="OrthoDB" id="5366687at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="259" mass="28948" checksum="B15BE19DE5BDCEB7" modified="2020-06-17" version="1">MWCSMPSPLERSRVATVGLFYMCLIHICPLSSRPFVLLKHPDFSASLEKFLTPPNSSVGIYLYQFSETLIHIVQGCGPPKTLSVLSKSTPPNSPLRPLLGSRNHTSLLYLATPRQPHYTYRLRPLRLHHTLQMAEQGTVSAWLTALRQIQENLEDDVDYWQGQVELARSILDDVASTTFLHDGGQWREQVRVISALQSVAFFDADSGYVADMAHWCLNSLLAILQHHPNDSAALYSTSWAPQKGATSFSPHLLTTVPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLS3</accession>
    <name>A0A6A6NLS3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alb1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_155603</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLS3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053278">
        <property type="entry name" value="Pre-60S_factor_ECM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022784">
        <property type="entry name" value="Ribosome_bgen_Alb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280:SF1">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09135">
        <property type="entry name" value="Alb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2452599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="21847" checksum="F310822BD52A91EB" modified="2020-06-17" version="1">MAKTAKMKSKPPTKHSRAARRAASPSIDTDKSLKAIAPPKSKTTYVAPTPVRTGRVSKQKPKRRQQRERRQRGVERADVFADKLEKKVEDSVGRGKRAKARRAEWEELNKVLSGTDQGSKHVNAFALLEERRDGGTAAIDDEVMEAADANPSADLSVKESHTAVAVLRVKYDVPAAANMEQTGAMERNPYDQGEDEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM25</accession>
    <name>A0A6A6NM25_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Enolase C-terminal domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_358175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM25"/>
    <dbReference type="OrthoDB" id="14161at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000007">
        <property type="entry name" value="Mitochondrial enolase superfamily member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="5">
        <location>
            <begin position="36"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2452728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="286" mass="31862" checksum="E6D0ED459EB2112D" modified="2020-06-17" version="1" fragment="single">MLRAAREGRDVRLAAVSASRGVPAYTTSAGWLGYGPDKMRALLQEALDQGYRHFKLKVGGSVAEDRERCAIAREILGYDAGNVIMVDANQVWSVPEAIAHMEQLAEFKPWFIEEPTSPDDVYGHKQVREALRPYGIGVATGEMCQNRVIFKQLLQQGAIDVCQVDACRLGGVNEVLVVLLLARKFGIPVVPHSGGVGLPEYTQHLSTIDYVVVSGQKSLLEYVDHLHEHFLHPSEVRDGHYVTPMEPGYSVEMKPESMERYEFPGKEGISWWKSDQAKSILDGERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM48</accession>
    <name>A0A6A6NM48_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_157263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001707">
        <property type="protein sequence ID" value="KAF2452537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM48"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="159" mass="17159" checksum="2B5CE5D3DFC95643" modified="2020-06-17" version="1">MKLIFDATRRRCAVTRGVECGRRAHVGGGLCARGSAADAEGRVRLHRRAGRVRGRADVAAGDKRDAARSENRVGSALGRIPGASRRLAKLDVLDWRKLTVCPALERANSRGYKTPNALKRRGHRTSTELESWGCGTPSGPKSQCQSEGQKLARKMPGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMJ5</accession>
    <name>A0A6A6NMJ5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_358418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMJ5"/>
    <dbReference type="OrthoDB" id="3182339at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="9024" checksum="3AAA9E40638C0ABC" modified="2020-06-17" version="1" fragment="single">MLDVLDWCTATTCAFEEPPVMKPRKHSLHRTVRQPVQKGSLQASSDAFIPAFKSLEETIAKRHLQAASWPQDLLVTTDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMT0</accession>
    <name>A0A6A6NMT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_148987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMT0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="14117" checksum="4D08D4F1EE048F81" modified="2020-06-17" version="1">MPAPKFRPTYPSPSAPGTTNKALANGPYTHQSPRTPHHPGVYRAPQSERSHLHTTQGTQAPSPVRFGAARAGRRAGRGRGRGRERPSRLAVLAEEVRGKLLPVAEECTQVDDRRLWTWVRDFCGRVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN96</accession>
    <name>A0A6A6NN96_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_375309</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN96"/>
    <dbReference type="OrthoDB" id="5553476at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046132">
        <property type="term" value="P:pyrimidine ribonucleoside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000008">
        <property type="entry name" value="Orotate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="66"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2452733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="25955" checksum="0269D2B3815237C6" modified="2020-06-17" version="1">MSSKSQLAIAPYKAEFLKTCLEGDVLKFGTFTLKSKRISPYFFNAGLFFRADLLHSISFAYANALAEYAASNSLEFDVLFGPAYKGIPLATAAVDKLAAIDRAKYGRTSYSFNRKEAKDHGEGGSIVGAPLAGQRVVIVDDVITAGTAIREAIEIIKREGGTLVGILVAFDRQEKTPSLTDDDGEPRPSAIGEVRKQYGIPVLSILTLDDVIEFLKGLGTEEDLKRLEEYRAKYKASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNE9</accession>
    <name>A0A6A6NNE9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_128338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNE9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="20823" checksum="BA508A501CFCE8D4" modified="2020-06-17" version="1">MLSRCACPRQRTRVVVRAGPPTVRLTATACSPTGPVLHTAHDTRPPGAYIRPIPKYPSLGACSCRCALSRAPPERALEGAQHAYSRTARPLGCRTSTSKPLSSRIARSRCLHAKPSDPHPGSSDAWPAARALAASLHATLVWIRLNSQRGDSLAAAPALATGALSRFPASPVYCCPLKTPIEADRKNIPGHYMYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNN3</accession>
    <name>A0A6A6NNN3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_424822</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNN3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="77"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="353" mass="40044" checksum="35F40CFF766588F5" modified="2020-06-17" version="1">MPPKKSSKTTSGTQSQAENSPSETLCTIGASLSDFGYDLHALPNKFDLHEFTKYVRQFEHGEFEDLFTALRDIDKVLKEQTRQYKLKQHQQEETEAENTLLKDRLVEMEDVLQAFEKETAKLRAQAQNPNAEPQSTSSLLAKLAKPTAQDPPIFDGKDNRTKGQAFTRLETVQNLPEAFSALTQLYGNKMETAKGRADLLMMTMRTDESLEDFHCRYISTTNMAKQNPVPQTFITKLPPRFVRSLTSFKLEEDTTMEQLMAYLGNVDINFQRMNVLFPNRGRGRGRGIDRANQDRNIPAPTGTSAPRAKLTPEERDRLQKINACFYCRKEGHAIRQCPVLNKNATAASEMKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNS8</accession>
    <name>A0A6A6NNS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_145486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNS8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="152" mass="16788" checksum="9D6567E354D3C980" modified="2020-06-17" version="1">MGQAFVEIIAQPLCNAESESQQRCFSESQRRAQVLGWKARPCRPPVSGCRESRLRSRNARGKQRRSGVGGAEGRSSPLLVAGAIGALSNSVHASPLDWNALPVHDVSASPADIAESCRCRRRASIRRTDRARNRAGFWERGLLPRWLDVVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNV6</accession>
    <name>A0A6A6NNV6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_366953</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNV6"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="125"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2453396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="417" mass="45468" checksum="1DBB77EB110F0D9C" modified="2020-06-17" version="1">MASSVLVILKTGATEAPLKLPVHANTTFRCTPNHVVYSDLAETIAGIPLEDVLADVSPAIRASHPDFALYEAMHAPLRAEDPHGPRKGRAALDDAAAAATAAAAWTLDKWKFLPLARRALARMPAARWFVLVEADTYVVWPSLFDWLAGLDPDQAMYAGAPTQIGDVTFAHGGSGVVVSGPAMRRLVETVEADGVAAWEDVTTREWAGDCVLGKALGEAGVGLTWTWPLTQGRRPGSLDYGSAMWGRRAWCYPAVFYHHVDAREIEGFWEWEQEWYSRGLPRIRHSDVFADYIAPRLATAPEPSRDDWDNRSDYAEAEGFQTHPANASSSDGGGCARRCADWDECLQWELKGGTCFLAKVARLGNPVVGSSAGGVGVGVKEREGDGEVQSVRSGWMVERILKRYGEQEECAGEEWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP55</accession>
    <name>A0A6A6NP55_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_127453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP55"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="335" mass="36100" checksum="FA66AF2B4AB147BA" modified="2020-06-17" version="1">MRAIEIKQYVKDESELAVTSIPDPSPAPSEYLIAIHASATNFFDILQIRGKYQHQPPFPWISGSEFAGVVLRSRADGKGKFKVGDHVFGASQGGYGTMIAATEQSLRPVPKGWSFFEAAGLFVTAPTSFAGLVTRAGLKKGDWVLVHAAAGGVGLAAVQIAKAFGAEVIATAGTAHKLDVAKSFGADYTVDYRAENWPDQVRKLTPKGRGVDIVYDPVGLIAQSMKCSAWNGRLLVIGFAAGSIEKVATNRALLKNVSIVGLHWGMYAKMEPDTVEKVWEGLYRLIDAGKLRSTCFTDKEFVGLEAVPDALRALGARETWGKVVVKVPQDRSSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP57</accession>
    <name>A0A6A6NP57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">magnesium chelatase</fullName>
            <ecNumber evidence="1">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_356779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001699">
        <property type="protein sequence ID" value="KAF2453194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP57"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052041">
        <property type="entry name" value="Nucleic_acid_metab_PIN/TRAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603">
        <property type="entry name" value="AAA FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603:SF132">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ChlI/MoxR AAA lid" evidence="3">
        <location>
            <begin position="286"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2453194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="382" mass="41830" checksum="13363951485852C5" modified="2020-06-17" version="1">MDQKSHAFEEKVQALGDVELAALLCLVTEQHCIIEVDDAAVDGLVQELCLISDSTFGLPSAVLECSERTSLDDFGNAILVNDPDNECHSPQNLAKDAFSYFNADAPKGIYRSPSPASSRPIDNRKIANVVIAKNLNLAHTQVQIQALELIRGRRIFTRTAVHVVPKRFLLIAVLSASSTAALDPHLNDQFFISHFHSHSDDLPKLYEKQNDAFDDDASSESSVVRASFSMPVPDIKVPGRIGSATTGKGRNPEFTKEDIDAIIAASRAVRLTAEVRAYIHNVVVFMRLHRAVAGGVTAAATRHLHLLVRALAPLHGLDFLTPSLVALAVRKVYPHRLVLVRPEDERSLQWGSQEEAVRRAVEGIGGVEDVLEEVLQRVDVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPN2</accession>
    <name>A0A6A6NPN2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_417191</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPN2"/>
    <dbReference type="OrthoDB" id="336885at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="9">
        <location>
            <begin position="239"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="8">
        <location>
            <begin position="393"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR018300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="716" mass="76662" checksum="1E3B67A8D0765CD5" modified="2020-06-17" version="1">MSGDGTLQELFAPHGSLAPEVLGELRSMMRLYSVDAEELFMKWEAYSLKMTGGGARGGANDGGDLVLDVKTARDFKKDIQDALERENRSKVAHMKGTPAARRAGATPKASMASDGVYGMLDGIVPNTPRPAALSAVNGNATKRKSNFETPAAKATKNYLGSSPADSKTPDAHTQLIFNRDVPFSSRPNAGEITQSLNDNIEIPAPPTVPQPKPRIKLTANMDQPKFAYKTMAMKLSEASETLDDRIDEFRALLAAAHGLGPDAFGNPAAQSTAEIVAVGRICSDYVGGDPRGAGKLNAASLLLETSRRNGNGYRVPLKVDKLPGYDFFPGKIVALRGTNASGEFFAASEELSLPLMDRSVVSQADLEGHVARLGTVPAGDDEDEARPYPLTTLVASGPYTPSSSLDYSALHELLSTAVTKRADLLILTGPFLDIEHPCVRSGELPELPPHITGGDPDAANLAAVFKHLISTPINQAVQNHPGMQVILIPSPRDAVAHHVAFPQDRLPKRELGLHRGTSCVVNPATLIVNEAVVAVGAVDTLDMLRREECVSGVKKAEHIFERAARNIIQQRSFCPVWPPTGRGALVPGLEKVDVRGRVDESGNTIEGKEGEEGETEANYELDLPVGTMLDTTYLNLASWTNTLPDLLVLPSVVTPFVRVVDGVVVVNPGTLSKRKGAGTFAHLTMLPREISDEERESGKMCGANLPSRARVDIVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQK7</accession>
    <name>A0A6A6NQK7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_291983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQK7"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000426">
        <property type="entry name" value="Aldehyde reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="345" mass="37738" checksum="8A592A4541590B09" modified="2020-06-17" version="1">MAPPSSSRLPHGSLVMVTGANGLIGSHVADQLLLSGYRVRGAVRNADKSAWLTRFFADKYGPDKFELTVVPDMSAEGAYDAAVKDAVGIAHVASVMDWATLNDVNVVVPKVVRGVTNVLEAAAAAPSVRSVVFTSSTAAVADAVADLERTVDETTFNDEAVGRAFAPPPSEPAQRILDVYSAAKTLAEKAAWKFVEERKLSFVFNSIASNANFGRPLSVKDQGCASTLRWIRELTDGFPEMPFLKDLPPQYFVDVQDVARLHVAALTFEDVAGERIFACAEHYNWNDVLHIIRKKFPDRTLPDDFPGIGRDKTTVPQKRPVELLKRFGRSGWTTLEESVMMNLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR57</accession>
    <name>A0A6A6NR57_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_354436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR57"/>
    <dbReference type="OrthoDB" id="3796682at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="138"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="398" mass="44857" checksum="EF7A9045740AADA2" modified="2020-06-17" version="1">MRIKPRLAPPAGGRPQFSRLVIQHPCYDNFNTLLKLPVLDEGNTIDYGTALTTCGIVCDNSYGTGWFARSRDGSSICTPGTPLESDKYPVCPSWDHWCPPSNEHSLPSGFASFQIPDAPPYLGNGGFMDDLQRRDVSCRVTGVYDGCEQAHLVPASDQDWWYKNVAGTSGFEIESALNGIFLRSDLHRLFDAGAWVPMVKENRMVVHVLRDSTVSKQFIEIFHNREMQELIGIDKQCLFARIAYSTFSLLFDFLASRRLANDNTLFKFGDDIAEWSPDACKKWFKAKSRSRNPSPTKRLRVDRDGGDGDQDTVWCTYGPNVAVDKGKCLTENERPDNTDRSRSSASDGSYDEEENLPRGRKRRRSFDDRSFPPIFNSLPRCEGSALISKYEQGFGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRH3</accession>
    <name>A0A6A6NRH3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hypercellular protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_268170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27962at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058567">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058568">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26280">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26282">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26283">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="5">
        <location>
            <begin position="461"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="6">
        <location>
            <begin position="790"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 third Ig-like" evidence="7">
        <location>
            <begin position="1138"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 fourth Ig-like" evidence="8">
        <location>
            <begin position="1352"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="947"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2454390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1483" mass="160846" checksum="E27ED5AB7DBE4170" modified="2020-06-17" version="1" fragment="single">ADPLSPVAAARVRVQLLPVGRIKRCSFKSFVALLEAESTVRLGDVTPDSRPNRTMFSPLAFPNGSLLYDFSTAFPSASRVALAPFELFREPFVILGVADGAEYNAISKHAEHDDARPNGLINGTDPVEELRDGVAMLREEHPRALVHNLLVFNSSSPDRHAWMSEETILVPPAEQLKTTTMKTIICDLTSTLLAEMTSFAKSIQALPSIPSPSPSSHSSRDTPSQQRPVSLSRSNSQMSNGTRSRSPLPSRNTDYRMSMPAHLPSSSATSGTPDSLASSQPTSPSEGTKTPPTTFEDMPGIERSSSAASSGNSKMTPRPLPGDMAKNASSDRVSVQGFGSGSVSERARNKGKSRVGLVIGSFYLLAGRWQDALRELSEGARIARSLSDHLWHAKGLENVLVCLLLLGWSGMDFQIPQICYPIAEKTSSTKSPHHTPSSSATDVSRTDSSTPSSNAVALQNLAALLPDLINMILGIYNRSAAFAGEALPTLALSESTIRLSRLLATVYVEKGALTQRALRHAVMGAALDKRPDNRNFIAFTKSPSRHEVASMVFRAHPLPSELSALSFEDQVVILAGISSVLSTLQLQRKKGIVMKEMVSILIRGLVQARKVGAAEMGVHPAAGLSAMNLPGAGPGSPGSLNMGDDEVDAGLDSFLMALGRIYGIIDLRVVSKVLGGPLQDPNSDTLRELLLRKSSLRFFGSVHLKHDILRACINFCEALPDFQGVLNFSSTLLATAGPGSAPSPNSTNVFVALAREEQLRLANNISRTVSAAAKLGLQDVETDYWDDFLVRGVHVIDPPAQRFLTPHKQTELERAMAGQAKEKKSPFIHNPFLKEPTTPTAERLLVAGDRFEFVVALQNPYEFDVQIDELRLKTEGVPFESGLDNLVLGPYRTQKFTVVCTAKASGSLRIYGCEIKVRGCRLRTFPIYSKPWTPERDTRVKAMGLSATDPAHSRPISGVSTSSKGSKAAPNYPEASSLEFTVLAEQPILTAPYVSLPQSALMILEGERKIFTVTLQNHSNTAPADFVHLSFQDSSTSSLQASLGNKGLTPTEIHELEYQLAKLPAFRWRRTANQEEGTVILPGGTATFEIEVLGKPGLTDAVIQFDYANIGVPREEVKGRFYTRKLSVPITVTVNVSVQLHRLDVVPFSGDFAWWNQQRRLSRKHTGDAGETPTNRDLRFKLMLNQVGFDGKNTDYCLLLLDFRNAWPNPLSIFVQVLDDRITPDTSADEDAQWASAFTVHDTLQPGTVSRLVLLLPKQHIPDPYAPIPSLNPANQRQFVVSNASSRVSPEAERAAREAFWFRDALLRLVRGGWREDANPALSRSGAIDLRGARLGPSVVEAMRLDDVDIDLAVEMSSPSSSPSPLLPRQLGRARFAIPIDRFVTLRASIRNRSRGPLRPLLRLQPALAAASSSGAAALSHGLALDLDKRLAVSGALQRGLGWVAPGGEVAARVALCALCEGMFEVGASVEEMVVGRAEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRJ7</accession>
    <name>A0A6A6NRJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_353920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase VIIa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRJ7"/>
    <dbReference type="OrthoDB" id="5511599at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.91.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039297">
        <property type="entry name" value="COX7a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036539">
        <property type="entry name" value="Cyt_c_oxidase_su7a_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02238">
        <property type="entry name" value="COX7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="70" mass="8247" checksum="548367673B61EADA" modified="2020-06-17" version="1">MAGWPYYRENNVPKWQRIHQTHDGLRQWEKGPRGKMLTVPFFALFWTGLIGSTYMMGRMVFGHKTLFGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS83</accession>
    <name>A0A6A6NS83_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_100364</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS83"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000630">
        <property type="entry name" value="Zinc finger protein 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001156">
        <property type="entry name" value="Zinc finger protein 407"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="392"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="428" mass="45250" checksum="7CC27FA8EAFEAFE5" modified="2020-06-17" version="1">MHSGPESLGGGPPSFTARRPHASNLPSFELPPPQLPHAQKYPYSAPMSASQPHQPQGTVASVGNLLTPPSNIPGDGISPVSTGVSSSGVNSSQGVPYTTNGGYVWSPPTTGGNAPYGFQTHAGGNPQQYPPRAPQQPQYDMNSNPQFQSSGSMSAPSSLPTMSNPQHSLPSSAMMSSQPPATTAPPQQSPVHTQEAFHTQRPPPTPTYYHSQQSSAPQQPNYHYSSTGPSPTVPTQPSPMSVGSQIPRMSPTHTAGPVPSLPSAPAQSPHHYQRPFGHYPLPGPVLSNINNPNGSMTLVGGGHVPHGMIPNFNSGHAANMPHVYGAPHAPQAQPPNDRPFKCDQCPQSFNRNHDLKRHKRIHLAVKPFPCGHCDKSFSRKDALKRHILVKGCGKATSGGDNEKGEKSGPPAEKLEDTADRKPVVGSHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSM8</accession>
    <name>A0A6A6NSM8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YOR181Wp-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_291116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSM8"/>
    <dbReference type="OrthoDB" id="8963340at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045010">
        <property type="term" value="P:actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000281">
        <property type="entry name" value="Actin associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2454736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="147" mass="16793" checksum="4A1650AE67C0455D" modified="2020-06-17" version="1" fragment="single">MPSILSDEDKQTVKRQVPKPSNKIHAVAVARLYVAYPNRHRWTDTGLQGAAVLANDLVGNTFWVKLVDISPANRGVIWDQEIYDSFAYNQDRTFFHSFELEDCMAGLSFADEKEAKTFKRKMDEREKNAHKNTKSKPFAISLSASQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSW4</accession>
    <name>A0A6A6NSW4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_96254</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16568">
        <property type="entry name" value="RING-HC_ScPSH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="132"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="713"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="478"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="529"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="619"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="718"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="771"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="790"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="833"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="863"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="881"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="936"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="988"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1014"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1076"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1130"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1181"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1206"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1225"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1255"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1275"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1285"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1338"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1358"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2454885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1371" mass="147555" checksum="A094360791FE7DAE" modified="2020-06-17" version="1">MDTRPGAAASPAAAAAPSGSRAARQKTPTESSVASATPSLSNVSPGKQGATMPPQPPGSPSGVKPSGLPGARTRPLARAANSDSRPAHSASKDSLKAKIVRRQEDTSQASKNEELLKSLRSDFDSLRAIITCKICDKLMYEPYITSCGHTYCYTCLCTWFVNNKEHKTCPDCRGMVTQAPAPAYLVREMAVIFMNRTEFLPGGETLDQHLTWQKEEADIVLKDRNNKDPRTGGLFRGCFRQRPPRRRPIRDEEDGVDRCPMCTWELEPGALECDRCLAQWEYEGGGATWGDSFAGFSDMDETSEQDLSGEDLDHDLDLEDMDDGFGYDEFDYPMEDYQYLVNEWLNGNMPPQNMPGQPPFRGPRRRAAHSAAGSRRRSYSASLESEMISEDTEMGTLEEEDEEGLDDGDSSMSGFINDESEEASDMSSSAASRTPQPEPVQSRSQRRRPVVISDTSSSASRATEDDNEDEGPIDHSGRARRRQQQVNSRRRRQITPSESTNDDTASVVQDLEEDRQALLHQQGWSPLEQDVDEEMTEDDYDSDGGRTTVGPNVSIRPPSRAGSSRILDGSRGLRRRSSVLSRQSAANYEDGDQADDDDSDAGQDRDGDIPMNGPIIRSRPSQLRLRNSTPVRGPPSWDTNNGRGVSLGDPNDADDGDGSDTSIQPNRRRNRQGSRQPEYDPRISYMFAQHLTDISRASAPNYFDALELRAATPVQRPRTANRNRPASQGSHASGALSPHSPPNVPARLRTPSLDSIISGGPMNSPSRGEQARTSRNSLSESSNASGGVQIRQNSMENSSYNYSPSTLRSPFHGPPNPGFFPPTVTDIIDRPASRVGSRPGSAASRRGSNGFVPAYQPPGFNMAPRAFPNPLNPFFRPRPRQSTQRLREQASNATLRAPRSTRTLRTQPSQASIIDPGQYAVPQQAIRPQSSRIHLRSQPSQPRLQSQSSTRTLRNSDHRATAATRPISPQQQQFHYQRAAPMSPVAPSRTTASSAQSAVPPVGGPSHRSNLTGEEVRREEVRRRGQELMRQRAEELERQRLAGLEPHRLAPDVDTNPFAAHRRQQRGESTANVSQAGRPTSSSPTTTSGGAPATGAQPRRLSSVTRSVGADGINSPSNSVTPPAGPVSPPASAAASSGPTSRQHQSPQQQQQQQQQQQQQRQLHQQRQPSASSSSNVPSQTVTAGPGNNTNGRMSTSSPSGPPHPSRGLSTSGGTRSPENQAAGPMPSTSGQASSSASSPGMMRRGSGRNIGDWTGNNNMSGMTNGLREGGPSLGPSAGRSAVPPGGGAPAVSGGAGSQPRIAGTQQGLVDRDEGMYRGRRGSSSGGSGVAGYEERNGPGGVGLGAGVGMGPSLGRMGVDRRASAVAEGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSZ4</accession>
    <name>A0A6A6NSZ4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_373894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSZ4"/>
    <dbReference type="OrthoDB" id="4940137at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="138" mass="15962" checksum="612CB54682E0E395" modified="2020-06-17" version="1">MPAVRIPRKKEFWYKPVFRKSPESVEVPEKLGQLLAASTFDNNSENIGKAGGFPDRFQSYNYRRRNLEILNNILKHLGLQYDENGPMGVSDEVMRIIGSDSTIHQLERKWSDLEATLQARYRKFTKASGVDGKMREQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT09</accession>
    <name>A0A6A6NT09_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PinX1-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_399035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in rRNA-processing at A0, A1 and A2 sites and negatively regulates telomerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINX1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT09"/>
    <dbReference type="OrthoDB" id="29523at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF31">
        <property type="entry name" value="PROTEIN PXR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="G-patch" evidence="9">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="368" mass="40818" checksum="22996AA5212EEA5A" modified="2020-06-17" version="1">MGLSAPKKRTKLSHDPNNTAWARSTTRFGHRILTAQGWTPGSFLGARDARHAAHYTAGSAAHVRVALRDDNLGLGAERKAAENFGLAAFRDVLGRLNGESGVLGEGEVRAKREVGVRLYALGRWGGMRIEDEVREEEEEGVSGGEVVEEGEGKRKRKRGEEAEDADGVRVSKKGKKERRGEPSTKESATKKRKQNKIDEIEDDSKSKRSRKAQKIDDRKARSLDTSDGFVPTEKSSEDGHMSTKIEPTPASIDEKAERKLRKQARKEAKEQKRADKERRRAEKAERKMKGRSASPVKKTAPSSSSEANTNGLDFTIEPTTTTTDATAKPSTRVLGARHFARQRMIQSKRMVGMDPKAMREIFMIKAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT63</accession>
    <name>A0A6A6NT63_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L38e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_351917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT63"/>
    <dbReference type="OrthoDB" id="10250488at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2454919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="9491" checksum="082B7B80BA0989C2" modified="2020-06-17" version="1">MPTEVSDIKQFIEICRRKDAKSARVKKNRATNKIKFKVRCKRYLYTLVLKDSDKAEKLKQSLPPSLTISDVPKKNQKGKRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTM6</accession>
    <name>A0A6A6NTM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_352295</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA43 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTM6"/>
    <dbReference type="OrthoDB" id="10250504at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04328">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000004">
        <property type="entry name" value="RNA polymerase I subunit Rpa43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041901">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="9">
        <location>
            <begin position="99"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="RPA43 OB" evidence="10">
        <location>
            <begin position="182"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="306"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2454623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="352" mass="39565" checksum="314340793512CAE4" modified="2020-06-17" version="1">MASAIASPEVSNRKKRKEHKKRKKHHHDSEKKSSKKRRREELDEPAAEVARETSPKKKQRMHADYDSLFHQAESGADVPAWFKNAPAAPDSPFMLQTTSMYLPLSPITLSDPIDGIRAEHLSPLLLTYSPMLKGIVLSYGNIRLSEQPHSGQKEGEQVLARCVGEYGPCFVWVTVDFLLIKPRRGLTVEGWVNLQNESHLGLVCWNFFNVSVDRKRLPQSWKWVEPGLAGHQNRASNGGTNHEEVENGYFVDGKGRKVEGFIQFRLRDFETVPSIESGTEFVSLEGTLISDEEERELAVRELQKKQGKVNGIVRQSPHPVPLPSSLKPSGATDKSPKTSKSKKPCKKDKGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTX5</accession>
    <name>A0A6A6NTX5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_71531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTX5"/>
    <dbReference type="OrthoDB" id="6080404at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03399">
        <property type="entry name" value="SPFH_flotillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF31">
        <property type="entry name" value="FLOTILLIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="26"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="515" mass="56683" checksum="9FD6E766B68E6829" modified="2020-06-17" version="1">MGFWYHVAESNSYLVVTGPGIEEVLIRKKAFVFPFQKVSKISVTPFDFSMSLQAMTVEKLKFSLPAVFTIGPEDTVESMTKYAVLLTGESDGRSTSTRDIVGAGRNHVQDIVKGIIEGETRSIVSTMTMEELFRERKVFKAKVIQNVQSELDQFGLKIYNANVKELQDTPGSEYFAFLSRKAHEGALNQAKVDVADARMRGEVGEAEKQGRTKQEIAKIHAATAVLETERKGEKATADARLTDKEIRIEQELNLARIDARRAAEQRDAELQKVVEQKRAQMELERLRATTVTQAQIDKEAAQQQADGDLYAQEKGADGRRYQEEADAEAQLFRRTKEAEADFIAKEREAQATLITKEKEAEAMFVMRKREADGLLEMAKAYGALADVMGGPDGLMQYLVLQNGTYEKLARANASAVQGLQPKINVWTTGGGGGGQGDGADPAAPIRNLFQTLPPLFSTINDQTGIAPPAWMAQMPGQQQGYGGRSGADDTALAKKQQQQQQHYAKASTNGVPGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUF4</accession>
    <name>A0A6A6NUF4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_96654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUF4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="21426" checksum="551C8854C680A6F7" modified="2020-06-17" version="1">MPGWTSPEVRYIKRISHAHQELSCPSQATRSTLYNRSSTTVGPLARFSFLYARLVSVTSSFLSAIVVPSCRWQSFCVSETLLIRRVLARRRRVAESFHKAPLAPLSRHAIPLSTCSPLFIAEPLKSQCGFYRHAAPRSVPWHEPVIGFRGRRSGSPQFPSARHYLTTYAVSRLIFWGAIFSPPYENFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUK8</accession>
    <name>A0A6A6NUK8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histidine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_97479</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUK8"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF38">
        <property type="entry name" value="PROLINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="63"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2454953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="564" mass="62139" checksum="4B8EA94DDAEEF415" modified="2020-06-17" version="1">MGHPEEAEGVAPLDEKPSSYDGRKGSVASGKRSHSVALDPAVLEGEIFDTRYEKTQRGLKSRHAQMIALGGTIGTGLFVSSGQTLARGGPAFILGSYIAIAFLVFCVVTAIVEVAAYLPTPGSSMNLFAFRYSSRSLGFATGWLYFYSLGILVPYEITAAALVIEYWNPPVNIAVWITIMLVVIVGLNALPVRFYGETEFWFASTKVIMMIGLLMLSFILFWGGGPKRDRLGFRYWQHPGAANTYLESGDLGRFLALLSTLVLSSFPFTFAPELMVVTAGEMKSPRKNLPIAARRYIYRLIFFYIGSVLAISVICRSDDPALTSGGTGAGASAFVVGIKNAGIDVLDSIINAGILISAWSSGNSFLYLSTRSLYSLALSGNAPSFFKACTKSGVPYRAVATSSLFCALAYLNVASDAAVVFNWFVNLTNTSGFISWITCMITYMRFRKACRVQGVTQLPYTSIMQPWGSYCALIGFTFLCLINGFNVFWPENWSASNFLTAYVGIPIFLGIYFGHRIYAWRDPWMHPSDEVDLHTGMAEVLAEEDGKPPRKPEHWWEYIKRIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUW7</accession>
    <name>A0A6A6NUW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUW7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="113" mass="12383" checksum="D18194776AE55265" modified="2020-06-17" version="1">MSRRIDSASASDSGRDADISPSAGPASESYLDSDDDAETELNGEFANHWSGHGMGNGTELDTRDVLLDPYLTPIHGLITSEENFAMHIQDLYTILHAYRADDTGQMIQRHNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUZ3</accession>
    <name>A0A6A6NUZ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_386936</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUZ3"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000042">
        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="301" mass="33193" checksum="250C63F89F9DE269" modified="2020-06-17" version="1">MLLPRTYMLALRATVSNSPISNVLEALRSAPSQTLQNLARVRYAHHQSEGRANGVKDGPGKRLGAKKTAGQYVIPGHIIFRQRGTKWFPGENCDMGRDHTIFAARAGYVQFYRDPLKHPKRQYIGVTFDRDDKLPYPPNAPRRRRLGMVATDSPSGPPAESIAASAAAEADMSGGNALVAAAAAQAHNSRGRDLMATGTVAREVPRRLGRKGGRSVSYLDRGEDGMPLAPNARTRGMYREANWEIGRAAEREGIKVKKWVPGDRWSAWRQRAKRRERAQQMSAMRSGGKKKGKGKKGRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV08</accession>
    <name>A0A6A6NV08_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_349747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV08"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="8948" checksum="2DB61A0F315F0F30" modified="2020-06-17" version="1" fragment="single">MYICTSPADHALIVLALGPPYCSALSFRPTACAIPMGTGKATEPSRVVMQNRAPRLHGQIRLPYSVLPPPPSPHVKSINRESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVP8</accession>
    <name>A0A6A6NVP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVP8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="111" mass="12027" checksum="5CA64DA0392F2EB0" modified="2020-06-17" version="1">MLLRPLQAVSSINGRWSRLLSVLAAIAIGVRGQFQSAISVPPILPRSPPRSCGVEETRLLAVQTAPVSKFESAPSSASDHVRTPTYRSPFCSSTRLLLLLLRPMPPPRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVX1</accession>
    <name>A0A6A6NVX1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative pre-mRNA branch site protein p14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_289623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVX1"/>
    <dbReference type="OrthoDB" id="275748at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000286">
        <property type="entry name" value="Putative pre-mRNA branch site protein p14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="3"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="105" mass="12125" checksum="A74C2F29F352C434" modified="2020-06-17" version="1" fragment="single">STRALFVKNLSYNVTPEELFDLFGKFGPIRQIRQGIANNTKGTAFVVYDEVMDAKSACDKLNGFNFQNRYLVVLYHQPEKMAKSKEDLAQRQANLDRIKQQHNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW70</accession>
    <name>A0A6A6NW70_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_364788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW70"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="30760" checksum="872986DE34026202" modified="2020-06-17" version="1">MTPRVFFITGTSTGFGKEYVNIALSQGNYVVATARNCSALSFPDATDANCLRVNLDVTNKAAIDKAFDAAMNKFGHVDVVCNNAGYGLMGEFEAMSDEDIRQQMEVNFFGLVDVTRKAIQIMREQKTGGVIQQVSSFGGRIGVPTGSMYNASKFALEGFTEAVALEMKPEWNIKFTILEPGGFRTDWAGRSAQFPAKKHPAYDHVDGRARMAARHGTQPGDPKKGAQAFYDLAVMENPPIRCLVGTDAFALMKKKLAADEKLLVDFEKISNSTDIDGYVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWR0</accession>
    <name>A0A6A6NWR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWR0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="289" mass="30796" checksum="749F78CF47C2B1F7" modified="2020-06-17" version="1">MEATLHRQGLLLRAAPRAFGGRRARLGAAAGLGAGGRRPGRSYVAGGRMGGPAVACEMGHRPAKAGAIAAATAPRLADGRAAAAIHSGPAPPPRCARNARPSRAASKRAWQQRRAGACRGEAEAGKKRLTVNRPVRRQQRRRRRRWWWWRRPQPRARARSANGTFDRPNPRRPTYVGPPKRRRYAKQQLRAAGGFAERRAALGASEEWSAARCFAAPAARCCAHAAAPLAAQARGGALGRPRLACRLGYRRPQAAGGLAGASPGWPISPREAPAHESPGPLAEPACAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWS6</accession>
    <name>A0A6A6NWS6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Beta-glucan synthesis-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_386662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWS6"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02180">
        <property type="entry name" value="GH16_fungal_KRE6_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF14">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="10">
        <location>
            <begin position="102"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2456245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="507" mass="57483" checksum="4265E98589D9CCC8" modified="2020-06-17" version="1">MDEKEDDDDLHMPQDDDDVKYKPQWKDHFTRENIGSTCGLFFMILGLLFLFLILPILTSVGVIEWNYTYGTPLDQMPKFGDEAQAWAIVNNETYSLLKNVRTDLIDPDTPDSAMTRESVDGDELELVFSDEFNDNNRTFYPGDDPYWFAPDIWYGATKDLEWYDPDAATTWDGVLELRMDKFQNHNLNFRSGMLNSWNQLCFKGGVFEVSISLPGPGGVMGLWPGAWTMGNLGRPGYLATTDGMWPYTYNECDAGITPNQSMTDGTSRLPGQRLPSCTCSDEDHPTPGNGRGAPEIDILEGSADWGGLGLGVATQSAQIAPFDIWYYPDYDFTEFPNYNISYVNTYTGGPYQQAVSATTMLNNDWYDGRMYQKYAFEYIPGDDEDAYIAWYVGDEMTFKMDARAIGPNGNVGSRLVSVEPMALVLNLGISNNWAMIDWPNLVFPTVMRVDYVRWYQKKGNTSVTCDPPGYETTQYIEDHLAAYTNPNFTHWNESGYEWPRNSLVNDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWX4</accession>
    <name>A0A6A6NWX4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U3 snoRNA associated-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_47627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWX4"/>
    <dbReference type="OrthoDB" id="5423707at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013268">
        <property type="entry name" value="UTP16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08297">
        <property type="entry name" value="U3_snoRNA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="44244" checksum="5FFB59D14B56B469" modified="2020-06-17" version="1">MLSRVASFLRRSATPARSSPAPADAADTHADAQTHANEYMSQHRDMPAEPGEEGEQQQQQQGHKRSLDEAAPPSKKQRLGEGADVPAVAVVGEGSSPDHAASQKPDAAATGEASAVDGKALEIRTVESSTRDRDDGDDEGTEPEDDVVQQHVRFRSKSPPEEAIVDERAAHAVPRPSAEPDAAAETSDEQQKAWEGEDESSDEAPEAISGSAAADLAKAAQKGASKAIQEQEAKAKRSRRTRDELLKTQAAGSFRKHADKAKSKKRKRGGASDTSSDEEERPPPLRLASEHITSGYALPAELLNSIDEVRPPTPPRLEATPAQKTHIKFAEGPKAGKTPKDVKRGPVSVRVLDEQNPVLAPKADGAMRSVRERWLMGREGQGSRRGRKERRRPAANMERKGRKRGFLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXD8</accession>
    <name>A0A6A6NXD8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXD8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="67" mass="6828" checksum="12FD9784E2EC282B" modified="2020-06-17" version="1">MPRAPRRHGIVARPPGQPRALGTNIIVKPGEGGPASCFAESGVQAGKAGGELGRRACTNQLRTGPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXE1</accession>
    <name>A0A6A6NXE1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome biogenesis protein RLP24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_349137</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXE1"/>
    <dbReference type="OrthoDB" id="10262490at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000001">
        <property type="entry name" value="probable ribosome biogenesis protein RLP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF8">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="TRASH" evidence="5">
        <location>
            <begin position="6"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="202" mass="24206" checksum="3B7D9CF305E26903" modified="2020-06-17" version="1">MRIETCYFCQQPAYPSKGITFVRNDARVFRFCRSKCHKNFKMKRNPRKLAWTKAFRKAHGKEMTVDSTLAFAARRNVPVRYNRDLVASTLKAMQRVSEIRAKRERRFYRERMRGNKARQLEADRRLVAENQHLLPPEERDEVPLRERMELEEEQLERDVLEGHEEEEMLEEDEEVDTLPKSKEKRKQRLIVGYGPEDMDMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXG2</accession>
    <name>A0A6A6NXG2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MAGE family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_323805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXG2"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="58"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="328" mass="36782" checksum="41E4DA89BD419859" modified="2020-06-17" version="1">MPIIGRKRRAPTQDDDDDESPDVQQTQTQVQRRQTPPEDDFLDDEDAAEVLTANGLPTDQMVKKLVRLALAHEYARRPIRRQDIVEKVLGNHSRQFKNVFNEAQMQLRATFGMEMVELPLREKVSLREKRAAQKNESKSTSSNSWALTSTLPAKYRHADIITPPAIPIAEVESQYVGLYTFVISCIYISGGQLSETKLDSILRKMNAEHSTPIDKTEKVLARMSREGYIYKSKGEIPEDNDWVVAPRGKIEVGEEGVANLVRTIYGNTAPSDLERRLERSLKPNERPTTASAASRLVGTKGPMQSVGGARRGRGRPRRGGTRDDDGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXV1</accession>
    <name>A0A6A6NXV1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AMP-binding enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_348452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXV1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF265">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="447"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="60499" checksum="D3BC3B56EFCA7C31" modified="2020-06-17" version="1">MPFLAQRTVPISTQDLLSWTFDNPPYDLDKPIYLDCHDPSISFSSRQSKTAIRKIAAGLQNEGLQRGETVCIHSFNDVHYPLLVLGIIAAGGVFTGTNPGYTTYELAHHLKASDTKIIIAEPEILGAIEKAAKAIGVQDPRIFVFDNAHNSGKIPAGYRSWRSLLDHGETDWPRFDDLQTTQNTTAMLLFSSGTSGLPKPAIATHYNLVAQQTLVFEHPPVPYERRRIMSLPVFHAASAPNCHISPLRGGYPTYIMRRFEVEKFLRSIEEFSITEWIMVPPQVVAIINSPLGNRYSWDSVEQIQIGAAPLDKKPQARFKALVSKDIPVTQGWGMSETCCIGVRFPYPEKDETGSIGRWIDNIDVKIIDEDGNDITGYDVLGEVCVRGPTVSPGYFGEQEATKNSWKADGWFHTGDIMYCDSKTRLWYIVDRRKELIKVRAFQVAPPEIEGVLLTHPAITDAAVIGVYGPDNTELPRAYVVRAPSSEGQALTEDAVKKLVEESLAKYKWLAGGVVFTDSIPKTASGKILKRLLREQASRELKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY13</accession>
    <name>A0A6A6NY13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_379665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY13"/>
    <dbReference type="OrthoDB" id="5229455at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF43">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="51"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="879" mass="94813" checksum="92D6D1AB02D9FA35" modified="2020-06-17" version="1">MPRPKKAGAPEPKRRSRTGCWPCKARKVKCGEEKPKCLNCERQGEPCDYSIRLNWGGRTKRKDTDDGAPLSSGSGTISPHSSTFAIADFSGRVPGPPPAAFEELSKQFQTEPKSAASARFYSHASAPASDAAPVDPKLGNEPPQADTRGWEPLSFSEKWPQTSTNNPMLQILQRRAGQEYPPSSAPPNLEGPMSAGGNGYAQNSFPKSPPVQSMLPPGRSRVNQDSPPYVSGNTPEPIRSPREANKRLRLSPTADPPSSLPSGNLPANEPSFERAAPFEKANGSMGSVAPGQSPGQTTISSYSPFMATPLTPGSSVASDENVFRAGPRSTPASFQGSSDRRRLSVNSLLSAPPVSEASTGYSGAPSTERSYPVAETDDGYTRYGFDCGQPDLDTPKNDDAHAIRPIFSSPVAFANLPFEGDPHYHSEAGAAEFGFGLRPKDIAFERGGYYAKPVPIKIPKSLEPLPPQLHQNPMNLLYFHHFLNHTARILVPHDCEQNPFRTVLPEMAVRDENLLNLLLAFSASHRARLLNHKEPANRIALLVQNVFPALRRALEKDAQVTDANLTTAIMLCSLEIISPNTFEVPIPWQKHLTTARRMIIARGGLESVRPKDKVSYFLSRWFAYLDVLGSLSGSKNDAPMSSSYWAASAAPGGGGGSTDVSSGGDPGSSETDEIDCFLGFTSRCIGILSRIAHLAKRCEAERLDAAGEVRPGWAPSAEVVAAADGLRDELATARRQVVKGCSHGRGAGAGARSESEAGWDSLEVYATNEAFHWAGLIHLGRRVLGKPETDPEVQGAVREIVGALYKVRRGSSAEACLLFPMFAAGCNAVEAGQRGRIMERLQSVEGFGMTHVHRARTLMQKVWDTGKPWETLVTGEFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY22</accession>
    <name>A0A6A6NY22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitronate monooxygenase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_392889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY22"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="345" mass="35469" checksum="6C3F9F896C9828A9" modified="2020-06-17" version="1" fragment="single">TRPRQAASASSPPATTSPRFRPTSPTHAPSWTRLPRRPRDCPPALRRSPSASASSCGVPRCPPPSKPPSLPRRSPPRPGSSRRRPRPQLAAWAAAIRAATRGATRIWVQVGTVREARVARAAAAPDVLVAQGQDAGGHGRYDAAGLAPLVPEVADALAGRSSSSRETQAQAQAPPPPVLLAAGGIADGRGLAAALCLGAAGAALGTRFLAAREAAVAPGYRATVLAAADGGRVTRRSGVYDALRGVVGWPAAYGGRGVANRSYVDEVVGGVGREENRRRYEEAVGRADDDGEGGWGPGVPFGGRLTAYVGNGVGLVREVMGAGEVTREVREEGVRVLRGVAGGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYT1</accession>
    <name>A0A6A6NYT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_347104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYT1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="120" mass="13553" checksum="F566E62FBCFA4457" modified="2020-06-17" version="1">MCYNFISSLPLLSLFAALMTFLFLHRASPRLDTLGYVPISQVASVRIHRWPLRSAVLSGFLFNFLSRSAHLSIYPSLFFRSYLTFTPFRSIKSSKQCGLPATLSTFPAMKSLDIFNASSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ04</accession>
    <name>A0A6A6NZ04_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_46489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ04"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="163" mass="18212" checksum="5513D8E08FF6E2CB" modified="2020-06-17" version="1">MDPDTTSRNIFFERVCISRGSSKRALICSDRSTIDAGLRSSWRSKIFNGIRPSSFTASRSDMRVEVIAEPPEMSQPRQAEELSLRADTASRRRLAVLCLCRPEHTLIPLRNSSKALMKSVKRTPSSVVRHFRGNGHPLSPQLKSPHGQRPSRSSPFVASPVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ34</accession>
    <name>A0A6A6NZ34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_346610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ34"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="165" mass="18607" checksum="72420D215DCC0E51" modified="2020-06-17" version="1">MAASEVHLCGWSFAYFVVIREGRRPPRNEIQRPRTISSAIVILLGHQDRRRVGLCTVPEGERCGALQRHSFTSSHTGTGMYGRPLRPLPRPWRAREAAHPRSAAGKSPLHPYDGFRSHRRSAQRAASKSKMLLTGVDISVVHGEEAEERERENRFLVEPRPPQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZC0</accession>
    <name>A0A6A6NZC0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="11">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Biosynthesis of nicotinic acid protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BNA4</name>
        <name evidence="14" type="ORF">BDY21DRAFT_346198</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="11"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZC0"/>
    <dbReference type="OrthoDB" id="10053569at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070189">
        <property type="term" value="P:kynurenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000129">
        <property type="entry name" value="Kynurenine 3-monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 11" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 11" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 11" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="13">
        <location>
            <begin position="8"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2456832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="504" mass="55934" checksum="7C9395737B70164B" modified="2020-06-17" version="1">MSAMEGQKVVVVGAGPVGALAGLYAAARDCHVEIYELRSDLRDPSTVPLNFTKSINLALSERGINSMRNSGCPGLIDSVLADTIPMHGRMIHGEQSGELFEESQAYDAHGRFIRAADRGGLNKRLLDRLEAMPNVKFFFNHKLTGVDFKKKLAWFERRAYSHDDDQKNSREIEISFDFMIGADGAHSTARYNLMKYTRMFYQQEYIDTLWCEFHMEPKKTAQGDDFKLSPNHLHIWPGGKFMFIAIPSLDKSFTCTLFLPAARFAELDAAPSSVVPFFQVNFPGVVPDLIPAAELQAQYLANPHLPLITIKCAPYHFEGTGVVLGDAAHAMVPFYGQGMNAGLEDVRVLFDILDGHAGVGSATLPRADARAAALAEYSARRARDAFAINDLALRNYKEMRADVVSPVYRLRKRVEEALSVHVPSLGWATQYSRISFGNLPYAEVERLAQKQGKVLKVGFGVVVAMLGGVVGWWGWRLVRRGMLKAAMDRLSELAMRASQRLGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZD2</accession>
    <name>A0A6A6NZD2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_344960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZD2"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF37">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2457111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="48106" checksum="8E93278F3B5078EA" modified="2020-06-17" version="1">MPEPGSVLIVGAGTFGASTAYHLSLTHPSPSQIMLLDRTPLPPRPAASTDINKIVREDYSSAFYMALAVEAMQAWLTMSCLRNEVGERLFKRTGWVAVSKKGSDVARRIRENFGKRGVTNAEDVDLEQEIRERWSMVFGESDLSAMESAYFNPNPGIADAGVALEKMAREAMDRGVRFAVGDAVELVLEDGKAIGVRTLDGIVHKAEKIILATGAWTSALMASTEDKLDLPDSLRVESQVVAAGVCVVHYKLEDVEYEELKNMPVVIFGESGDLQPPPARSRLLKFTNAVSFTNTVTTASGRKISAPPTRDQGIVGEKLKKETIETHVRKVMPRFADRKVEYWRLCWDSIAPKQDHVICRHPDERLSNVYFAIGGSFHSYKFLPVIGKYVSNVVQGVSNGEERHKAWSWKMGNGGGRGAHEKAIPRRELCQVECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZS8</accession>
    <name>A0A6A6NZS8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_286266</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZS8"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="281" mass="31182" checksum="BAE1342CA5F9975C" modified="2020-06-17" version="1">MLGANQADPAAAQNNNGLLGAHFPLEQWFYELPICTRTWTTATVLVSILVQCRFLTPFQLFYSYRAVFVKRQVWRLLTTFCYFGPLSLDLIFHVFFLQRYARLLEEEAGGLGAAVPGAGGQVAWGGAARFSWLLAYAASALVALAPVFGMPFLGSALSSTLVYIWARKNPETRLSIFGLLVFRAPFLPWVLIVFSLVMHGSVPKDELCGAAVGHVWYFFNDVYPSLHDGHRPLDPPAWWCRLWEGRPQDHPHADEDLDMHNNATGAEPVINRDIAAAGAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZV8</accession>
    <name>A0A6A6NZV8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_364000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZV8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="19725" checksum="BBA8474978A1D709" modified="2020-06-17" version="1">MQGARSGSDDDSLGRSDWSVSPFCARLDLTASAFPLVETSTLPPYPGTPKQARVGSTLTKISTPAASHPSLGDTLSEQARRGEATTRRRWPRGVDYGVLMSVDDSSNNNSCRGSNDNTHDDGDVMRPFSGLRTRAFAFEQPSRAPSGWLLFWSTSERITRRRRRQEDPGLLCPSSRDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P072</accession>
    <name>A0A6A6P072_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ring-box 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_286182</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P072"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000010">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="56"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2457152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="111" mass="12682" checksum="C7AF7B242325429A" modified="2020-06-17" version="1">MADVDMPDVPAPQAKAPKTEGEGGKKKFEWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATTEECTVAWGICNHAFHFHCISRWLKTRQVCPLDNRDWEFQKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0V5</accession>
    <name>A0A6A6P0V5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">N-terminal methionine N(alpha)-acetyltransferase NatC</fullName>
            <ecNumber evidence="13">2.3.1.256</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">N-acetyltransferase MAK3 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NatC catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_385788</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-methionyl-L-isoleucyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50524"/>
            <dbReference type="Rhea" id="RHEA-COMP:12713"/>
            <dbReference type="Rhea" id="RHEA-COMP:12714"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133379"/>
            <dbReference type="ChEBI" id="CHEBI:133380"/>
            <dbReference type="EC" id="2.3.1.256"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-methionyl-L-leucyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12711"/>
            <dbReference type="Rhea" id="RHEA-COMP:12712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133377"/>
            <dbReference type="ChEBI" id="CHEBI:133378"/>
            <dbReference type="EC" id="2.3.1.256"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-methionyl-L-phenylalanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50528"/>
            <dbReference type="Rhea" id="RHEA-COMP:12715"/>
            <dbReference type="Rhea" id="RHEA-COMP:12716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133382"/>
            <dbReference type="ChEBI" id="CHEBI:133383"/>
            <dbReference type="EC" id="2.3.1.256"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N-terminal L-methionyl-L-tryptophyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50560"/>
            <dbReference type="Rhea" id="RHEA-COMP:12724"/>
            <dbReference type="Rhea" id="RHEA-COMP:12725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133386"/>
            <dbReference type="ChEBI" id="CHEBI:133387"/>
            <dbReference type="EC" id="2.3.1.256"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-methionyl-L-tyrosyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50532"/>
            <dbReference type="Rhea" id="RHEA-COMP:12717"/>
            <dbReference type="Rhea" id="RHEA-COMP:12718"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133384"/>
            <dbReference type="ChEBI" id="CHEBI:133385"/>
            <dbReference type="EC" id="2.3.1.256"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.256" evidence="13"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0V5"/>
    <dbReference type="OrthoDB" id="249099at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120518">
        <property type="term" value="F:protein N-terminal-methionine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000010">
        <property type="entry name" value="Putative N-alpha-acetyltransferase 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="16">
        <location>
            <begin position="19"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00052362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00076746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2457529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="189" mass="21570" checksum="8A53EE995F58A4E0" modified="2020-06-17" version="1">MSAHEASLTNVPELHFVQYHISKEEEYLPVIRQLISKDLSEPYSIYVYRYFLLQWPDLCYMAQDADQNLIGVVVSKLEHHRSGTHRGYIAMLAVEEAHRGKGIATKLVRIAIDAMAQRNADEIVLETEITNTASLKLYEGLGFLRSKRLYRYYLNGNTAFRLVLYLKEGTGLKCPVHPSAAGGEMRSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0V7</accession>
    <name>A0A6A6P0V7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_343857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 9">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26387at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.30:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase UBR2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="11">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="8">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="402"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="470"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="411"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="2157" mass="244417" checksum="3D78085A161BF293" modified="2020-06-17" version="1">MLFSPQEHKLCHSLRDLPFQFDNRYTDDAARTLLEVLFTSLAGDRDDYLALFFPHGTPPKDSRWSLRVAQGAIDGAEYTEGARGHPCGHIFKSGEATYRCKTCTVDETCVLCAKCFDASDHEGHTVYVSISPGNSGCCDCGDPEAWVRPMHCNIHSELPTAYPSKAAGKAKEAPGLPPDLLESIHMTVSRALDYLCDVFSCSPEQLRLPKTKESVLEDERLSRLNSKWYSGSGEEEREDKDDEFALILWNDEKHTVTDVANQVARACKQTHKFGLAKSNEINDDGRSVVEFSRNVPDLLRKAKIIEEIKLTVTVRSARDTFREQMCGTIVEWIHDISGCSVGADAKILRNAICEEMLRPWRMGSEAHHAKIGADGIDDHEVEDDQDGFPRLYQVGGMLVARARPRRRPQVEEPDEEQGDNDWDDDEDGGDAGEAGDDEMDLDHDPEAEDTMDLDLDMEEEDMALEHSEATLAGYPPPPPPPPAALRPPPTDGNTPADSDEGEFTPSQSDMVMDVPKTPKGRARSFRPPRPPKYWLEKPEGCTREHNLPVHEDLRQRVRLDFMILYDLRMWKKMRIDLRDVYISTVVTIPYFKRVLGLRFAGLYTTLAQLYLIADREPDHSIINLSLQMLTTPSITAEVVERGNFLSNLLAILYTFLTTRQVGYPSDVNPWATLAFEQGAVTNRRMYHFFLDMKYLLGSDFIQDVLDSENRYLLQFLDLVKLHQGICPNVRAVGEHLEYETDAWISASLITREINKLCRQFADAFNMSSAENFSHTCRAIRQTAKVVIINSLGAERRRFDQAEIKSETRFKTLRTFEFDMLLAGAPRYEVVDFTVEKEPMSFHHALHYTFSWLVDRGKAMTRDQLQDLLTFSVAELREAPTPLRAAIPDHPSSEYVQALFDFPLRLCAWLAQMRAGLWVRNGITLKHQMSQYRGVGHRDVSYSRDIFLLQTAFVVCDPSTILAQMIDRFCMEEWVRGKFQIRSGWEDHQVVDVGEDFVHLLIIFLSDRTALIPPNDDSNPHLAMVRRDITHVLCFRPLSYSELTSRLADKITESEEFSEVLSEMTRFRPPEGLSDSGTFELKEQYLEELDPYSAQYSRNQREEAENIYKNHMGKKLGKPASEVVFEPTLRPIRSGIFEDIGAFTRLPLFAQTIYYLLEYVFSANVYTPQIPSSRLESFLQFVLQLVLLAVLEDRPDEPDAAAFEGDRGFSYIALTADATDVLGRRQTIFSLLHFFTTTETYSSSWPKARLILQRLQQRWPSVYNTAMTELGLQPERMDTASPAVSSSAEEMEFKEKKKKEALDRQARVMAQFKEQQNSFMQNQAIDWGEDFSDEDVEEKPAEHEKIWKYPNGTCILCQEETNDQRLYGTFVYMTESAIFRQTDTKDGSWVSEALKLPSSLDRSADHIRPFGVASENRKTIEKVTSTGERVLTERQQLSKGFPKHCMKRGTLATGCGHIMHYSCFEVYIAATRRKHETQVARAHPERSGKHEYLCPLCKALGNAFLPIVWKGKKVSYPGVLEPENSHDTNDPFLDWLEKGIPLQISKLDKSPERSNPANPLLITRQQRLFRDYSEETMISQITSRLADLGRSAFFNLASDVQARRSDFVPTYLTVFQDAAGNAVVPADASTGPGMLGSPPPLELARVYLERIRDVMKANHLHTRHPYSPGSEDLVMTDTLSSTLGHSITCAEIAQRGVESSGSLLDKISPQSLTNLRVLSETIDSYIAIGVLRGQGTRNKTAHEFNDTQSRQLFQLLRGHPAFSNSAQLDWTQVSPLLREDAFQFLADASVYVAPAVHLEVHHVMRLCYLAEVVRVIVSFCYEHETVSVLAQMMEAAQHGQEPYKSVIEHQASVRSNTEILEFENVVWRIRRAYNSTPAPTNEGAFPLPPYPTPNFYHILRALVDAYTLPFLRKCAILLHVRSGVEFPSTPSSIAHEPELHRLTSLLRLPTVEEMISALNWDTSGLEPPSVLSNIVTGWIHHWAVSTQLREAKDMRMALPISLSHPGIFELIGLPKNYDTLTDEAIHRRCPTTGKELTDPALCLFCGDIFCSQAVCCTKDRLGGCTQHQAKCGGNVGIFINIRKCMVLFMNQGNGSWAVAPYLDKHGEVDPTLRRHHQLFLNQRRYDALLRAVWLNHGIPSTIARRLEGDINNGGWESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P299</accession>
    <name>A0A6A6P299_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_18176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P299"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2457862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="195" mass="22106" checksum="08CC96D4CF7EC03D" modified="2020-06-17" version="1">MPAAQFEAPADTPLLSRPLSREIVAYSRFSASSLCSRPAWTHPGQIVCFILPCRLPHLSRHCHGPIHGKSSSVPRFLEAYSFAFPRVSRARRYSEAVRAPAELCPTWMNGETFCKPISRTIVHASRQSCKGREMILYLYVLKVWNWRTIVIVNSESESRLVDGKTFRLSTASLFAKRPPWHLLMASINTYLLSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2A1</accession>
    <name>A0A6A6P2A1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Conserved oligomeric Golgi complex subunit 6</fullName>
            <shortName evidence="10">COG complex subunit 6</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Component of oligomeric Golgi complex 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_421529</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the conserved oligomeric Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the COG6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2A1"/>
    <dbReference type="OrthoDB" id="272987at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010490">
        <property type="entry name" value="COG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048369">
        <property type="entry name" value="COG6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048368">
        <property type="entry name" value="COG6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506">
        <property type="entry name" value="COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20653">
        <property type="entry name" value="COG6_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06419">
        <property type="entry name" value="COG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01087">
        <property type="entry name" value="COG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric complex COG6 N-terminal" evidence="12">
        <location>
            <begin position="56"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved Oligomeric Golgi complex subunit 6 C-terminal" evidence="13">
        <location>
            <begin position="200"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved Oligomeric Golgi complex subunit 6 C-terminal" evidence="13">
        <location>
            <begin position="485"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="363"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2457573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="781" mass="84217" checksum="7BE343EF80C8AA21" modified="2020-06-17" version="1">MTSSYFSPKEGSPPSSTPLGQPGGTVSRQTALSTRISAVLSASYSDLDIRNALETLDARGIKNTPETRRQLRLDVQREVIQCNGDIVKDFGQVAEQLRRIGTVIDKLNQTFADLRSHVNAADSATVPVLSESSTQLAQKSQTETKQRLLDAFTAHFTISEPDLVLLTSSAAPVDDAFFAVLARVKRIHADSQILLGAEHQTLGLEILEQSSRHLNAAFQKLFRWVQRELKSSAASAAAGGGGVDLEDNPHIHAGVRRALRVLAERPALFQSCLDFFAEAREHGLSDAFYTALTGAPPGGASSEAEHIATKPIEFHAHDPLRYVGDMLAWAHSATVSEREALEVLFIAEGDEIARGIQAGIESDPWLSRRQQQQERDGEEGTNEGASADSRPPVFDGRRALNELVARDLASVARLLRQRTEQVMQSHGEDATLAYRIANLVSFYRATFGKLIGGAPPSSTLPTDNHNGGDGATAGPAASAPGSPPSILDALASLEASALRHFRTAMRDHVAGVRADLSASTPVWTAAPAPADLAPPDFLDDALETLAALMRSYDGSLATTAAGAGPADAGEDEGFETVLREALDPFVEACAKVEATMPDPLSRNVFGLNCALRVRDVLAGRAFAWRARAERVVAAVDRHVDALRELQFGHMLGAAGAGPLFAALPPQRPGGAAEVDEEELLALLERPEFAPEALARAGQRLDEWLPSGLMDAVERLAGLRDRNIAQRVSEEAAERFCEEFERLEKVMGRVDEMVGRREGLEEREKLRDLLPRTSGEIRVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2D1</accession>
    <name>A0A6A6P2D1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_341768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2D1"/>
    <dbReference type="OrthoDB" id="4905832at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="75" mass="8466" checksum="1831FCC19430030C" modified="2020-06-17" version="1">MASGFGRQVRDEQSMDYFLAKYMWPQVNAALVQATSMFDWGDELFYLGLGNWCHGTGPPDYVGLVTNHRMGPGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2M7</accession>
    <name>A0A6A6P2M7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_342565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2M7"/>
    <dbReference type="OrthoDB" id="5421757at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="393" mass="43468" checksum="FF166CEEBF0076CB" modified="2020-06-17" version="1">MPPKQGRNTSFKKAQPKPASSTIPSAFHPTAPSTAPFQSNLKPGSLYLTHIDTHSPAEKRNIFILSLLPNALAVLVLAWRIRSAYPTYISLVAASLALPSAATVDIEQSTWANIASETLWRTAMLTCDLVLVTAAWKWVVGAFVSGPGYWRWKLGGVKEREVVVRMAKTLKSDDVLKDLKEEEEAEQKPKQLGTGVGTEKRDARSVSSSKDIVPRGLSPSYLRSKTGYLMQDREWALDFPAMVTAHLLLDSSAVSPTEFGPRVWAYCGEAHGWCVWDVGNVAAPSSKVASNDTSIASRRREEIEEDARRKMRQFETRVSAIGHEDLFFRWLEVLHYESSRPGANSWAPQEKKDNLLSSAKELFTDHGVDFEQFVAGLEGGISGVPGLAEEIWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2P2</accession>
    <name>A0A6A6P2P2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_284460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2P2"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="186"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="186"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2458285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="36042" checksum="2C97E2459D78A51F" modified="2020-06-17" version="1">MTGHQPSPSAYGQGPPPSAQTPQHQQHQHHPPPHHQDFPPPPPPPHHLQQHPGSRKRRRSREELQLDIQGLQGPDPDVGELGVDVPVELTPHGHHAQPQGLSLHYPAPQHQHPPPHAHQQQHLQQQQQHPPQQSTPTTTHHHHRLPNQPPMPKMPRHGYEGGSPVQASHGPPSMVGQEGMPAPAPRPRGPKLKFTPEDDQLLVDLKEKKNLTWKQIADFFPGRSSGTLQVRYCTKLKAKTTVWTDEMVQKLRTAMQDYENDRWRIISAKVGSGFSPAACRDKAAEIAAEEQVEAEAAASALPPGDVEQYAQGELGGESSDPPVPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3B4</accession>
    <name>A0A6A6P3B4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDY21DRAFT_205159</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3B4"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF35">
        <property type="entry name" value="PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025560372" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="21"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="212"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="546"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF2458520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="629" mass="68046" checksum="EF75193077EDF233" modified="2020-06-17" version="1">MKLTVVSAAALLSLAAAVQGMSTVLDSLRTVPEGWYSAGTPDPDLRLRFKIAVTQPNQALFEETLLQVSTPGHARYGQHLSRDELKALIRPRAESTTAILAWLRAAGVPETDITDRGEWIDFVAPVSCAEHLLDARFETFRHRLDPRGVDDQVRTLAYGVPEELRQHVRMVQPTTRFVQVRAQRSSVLDETVLGAFRSANVLADVDPSCNQTITPQCLRDLYNIGDFEPDPSVDMVLGVNGFLKQYARYDDLEMFAEEYLPEGVEANFTWTSVNGGTLPQDSDENAVEANLDIQYTVGLSYPIANNFYSSPGNGPLVPDLDQPTQASNQNEPWLEFFSWMVDLPDEELPVVLSTSYGEDEQSLPAEYARSVCDMIGQLGARGVSIIFSSGDTGVGSACQTNDGTNTTRFLPIFPAACPYVTSVGATRFVEPEQAIYFSSGGFSDLWERPAWQDEAVSAYLDKLGDQWDGLYNPAGRGFPDVAAQGANYHVVNRGAETLVGGTSASAPTVAAIIALLDNARAQVGLPPLGFLNPLIYAEGVAGLTDIVDGGSTGCTGRSIYSGLEAPYVPFASWNATEGWDPVTGWGTPDFGKLLEVVLEGMELPAMGGSNGSNVTVEGYRRSRIARGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3F6</accession>
    <name>A0A6A6P3F6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3F6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="21428" checksum="B7C0C1E2A006DC02" modified="2020-06-17" version="1">MAAISLLPRTPTLLPPLPSILPARPRTSLALTRPARHARLPFRRPRRRRIARRTGRTDGGAAAATRSGKGSRGAARGRGRRSGRGRGRGRRSQSRGRRCGLGGLGPRSGGVFTQGRGRRVCECCRRRGGRRRLEPVGGDARRVSAQLARRLLLRSVRAVLRAGCVGSGRARGRVRRVGRAGGAAARDARACGAGGVCDGVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3I2</accession>
    <name>A0A6A6P3I2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_218701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3I2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="191" mass="20781" checksum="984D08A11620CFFD" modified="2020-06-17" version="1">MTEPGKTATVKSCHQPHNLRHDVLARNHRTDNKGPAKLISALPRNMSTYTSKPACDHVNDFRDCNHGAPNALPDIKSPRRKLCPTSTCKMLEGQESDESEDSFADDSITDEVFIQASRNVSPGNSTFNDFRSGGQNTLPLASDVSTKDSQSSSIGKLASQVAESSTESSTESSRDAESLKRSFSEDANLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3M2</accession>
    <name>A0A6A6P3M2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_283827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3M2"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="346" mass="38122" checksum="C833DBDA1BCA52FD" modified="2020-06-17" version="1">MGEATGYGGPRGPHHPPSSSHPREFNYSTVRGIFLQDDPATNASDFDYTTVNLGLIDRSYETDHRCDPHGTKTQWERFVCYLNHLNRVAPHNVQYKLLIMGRHGEGYHNVAESYYGTEAWDCYWSLLDGNGTITWADAHITPEGADQAVRAHAFWHDALANGGIPAPQSYYVSPLARCLETARLTFSAPADLPFPADAAPFVPTIKELLREAIGIHTCDRRSSKAWIAQNYPGYVFEEGFAEEDPLWEPDERETNAAMDARLAQLLDNVFASDERSSVISFTSHSGALGSVLRVLGHREFRLVTGAVIPVLVRAERRVVERPSPTGVLSTGPPTCEVDPTASVGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3N7</accession>
    <name>A0A6A6P3N7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_302623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3N7"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF5">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="47"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="47"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="138"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="278"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2458434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="352" mass="39064" checksum="F5C828F7E8B53379" modified="2020-06-17" version="1">MHGISTKAENQLPLSPQYDLADGYDSPGSGDEDDNAKCSPREDPNEENHQPYARLIHQALINAPDHTMVLKDIYKWFEVHTDKAKNNKGTKGWQNSIRHNLSMNGGFEKVEPLPGEGAKSRNAWRLTSEALLHGVKSTTRYRSKTPHKRNSRSHVPAPQRQASGAKGGLAAKKAHMRQKQAERLNILCDPNVPIPTIETAQNMPIPSIEHAETPLSNPFQPWGTQQLFCRQEPCFADMSRSPMDWQDRGMDWPNQDLKIRVEGLPQEVLNGMNEHRDVQLQPGTESPQISGFYGAQPPVPFAHFDRNDPLSSSPESASHGPFTPADSTPADTYDAFGTSTDSSSLIPTTMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3V4</accession>
    <name>A0A6A6P3V4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3V4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="212" mass="21739" checksum="4C43C384D247D2FB" modified="2020-06-17" version="1">MVAWRQRASATALAPPAPPAAFSYVLPPGDGGRGGAGQARGDEWAAVGMALQEIGSADARAVSAEWKLLCGRVIAQVDACVQRPGVIGRLPAPNVLETASALRRTSRGNGKWRPAIGQSGGAAPVYLRARNMYMVHGFAEAAAGAEAAAGAAAGGQRRAASASPWQRRPPAREDGTDAGLREDGQLAMQTGGIQTARPVGWPAAGRRGPRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P420</accession>
    <name>A0A6A6P420_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_205011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P420"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="178" mass="18994" checksum="04214BE989D0F700" modified="2020-06-17" version="1">MPGPEIPRNTYIAIPANPSQSRPAQSQPPPTSRAGMPRRCGGGSSGGGSGNDGRSPRRTDRGRGEGGCALFLQRNERREAVGGRRLRSSPVPGAVPGHEGQSRGKSRARESVMKRGAKRQSRGSGVAAWSSRTRLSTYPSHPIPSREVGLVSTVTRLNQSVFQIVASFETSTADYKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P476</accession>
    <name>A0A6A6P476_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_363160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P476"/>
    <dbReference type="OrthoDB" id="5607at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000702">
        <property type="term" value="F:oxidized base lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47203">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47203:SF1">
        <property type="entry name" value="HYPOTHETICAL BASE EXCISION DNA REPAIR PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="2">
        <location>
            <begin position="149"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="435" mass="46940" checksum="FE6ADA7FEA7D7159" modified="2020-06-17" version="1">MKSSVIDGDELPHNLGKLPSVGANVSNDVSTPPAKKRKTRTSAIEVSGSEAIKDEKTLADVVAEEKLAISASSKGTQKLKDSGYGLKPGQTPYPEWPHPSPEECLEVCKLLAGIHGEVSKPEAIPPPSLTVTGCGEVPSVLDALVRTKLSAATTSANSSRAFQGLVQRFGILQEGIGKGSVDWDAVRRADVKDIFKAIESGGLANVKSKEIKAILQMVYEENQARRKELLATTDVEGEDKSTLDPGKLTSEAIEVRRAESNVLSLDHLHTLPSDDAFKALTKYPGIGAKTASCVLLFCLQRPSFAVDTHVFRLCKWLGWVPPDRATRNTAYAHCEVRVPDDLKYPLHQLLIKHGRQCPRCRASTGETSKNWSDGCVLEHLMKRSGTRKGGANTVKSTKFAGRKRGAKEMEDDDADDTKSALSSAGSGLDTDDEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4I8</accession>
    <name>A0A6A6P4I8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_339218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4I8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="80" mass="8899" checksum="C57FB72A12DADB9E" modified="2020-06-17" version="1">MRILEPPSSSRAPHPFHHDGIPPPAPAKAWCVGHVYIYDYIATYSPRSIPSPFHQARKVKTNKSESVKVSGLRPPPHPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4L0</accession>
    <name>A0A6A6P4L0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7165 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_411954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4L0"/>
    <dbReference type="OrthoDB" id="3925024at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055589">
        <property type="entry name" value="DUF7165"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23749">
        <property type="entry name" value="DUF7165"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7165" evidence="2">
        <location>
            <begin position="171"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7165" evidence="2">
        <location>
            <begin position="293"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="807"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="967"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1220" mass="127101" checksum="6409CA47AB7E58AE" modified="2020-06-17" version="1">MASRSPGRTTAAAPPTVPTSPVRPTLKTRFDGDATSDSGDGGKGAFRGEKDPATIPEDAAYVSFEKDIETGGQTTAAPQQHQQNRMSASLSSPESAGHDSSGRSTFSSVISGGDLDTMSLTSSPVGTMTTTATSALEAGLGTMTSSAGDAPGSAAAGPTSHPSGPATSDQPITTIIDFLSSSVTSSALPETLGLSVSRHGRYLLAFSSSHLYLLRAANLPSLRGARAFALKRRPLAVDVCDAEGVSVVAILADRHRVDVYDISSSGNGNGAGTGHAARRSGRQSGGTGNGGSVRLLRSVALVNPSRGIALAPDGKVMASAAPDCLEVVSLAPNATEADRRTLSCDGHESVVFSDDGTMLVATGPAANKGRRSGGKTTIYSVQSDLSPSLFLSEDAAGPPTEPTHISWIRRVLFPTVLPSARQAALIPDAHHLMDELLAFDVEADAFGVVEIATKSFLPHVRISVGIGAAGANRRRWYRRRGTGTGADCPPDATSDGGLEDALPGLFPDGTHVALGLKGRPATPGGTPGPSKIALYALPTESAALPSEKNGDNDEDVSHLRPTTSIPLQLASPDFAGSSAAVYGITGLRWLWDAPPAPGGGAASHDRLLATCATANSEADGPGPNGPSGPGSPPSARTRVEENAPETTTTSVGPEHATGRVVTVDFPCLHNRRARGRRGSNSDTSGSMEDTKALQTPPPPKRVEVVLDGRVRVERLPDRELDFQTEVELVRRRTVTAQRESERRRNIAARERERERVRERLDELRDDETDRRRDVLRSATTGPSSQMPRRRPVGGRSDSSGGRDRTTSRTSRVSSISSTSTNPVAASGHADDPDAAETDSVVSPEEAQAMFEAPYAHSQPRSQASLNRAATVAASSGANRRHLRALPSRPLEYRRADGLREHPHESDADDWVPPPPPYSEQVEWGSTSLGAGAGVNSRHGAGSRPGATPAQADQTARQRRNSGRRSQRNGGASDIPATTAPASIAPAPLGTPPWAPYASSSPGTFSTTSLPVAPPIPAVPSSPASTRSGGARLFRGASLFRSRTNSQSTAQPPQQPGQQQQQQQQQRVASPLPYPHHRQHYQHHQPRRPSTAVAAASSPAPAPVSVPPSPRPTRSRMARAGSLFRAQTSPAPASPAPRHPHRPVGPPRQHPPLSPLQPPPRLPQHAQSMAALPSAPRPPPSSLRGASPVVGVSAGRGVSPALGMSGEAGGGAGGRYPHPMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5F8</accession>
    <name>A0A6A6P5F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_384896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5F8"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06421">
        <property type="entry name" value="CESA_CelA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF2">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="524"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="656"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="700"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="765"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="9">
        <location>
            <begin position="358"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="783" mass="87755" checksum="D3E70081BEF8ECF8" modified="2020-06-17" version="1">MASIRQVDEDPNLSVEGEGDSIQATRRRASTEDSSSDSKNHSLAWTEDTAVATEQLDAIEKVEPLANTRPESYSDVYRPTGRPPLRSNGGHTSLQDLYAESPEATPLATPSAPWLSGRGHSPSSSGFTPTPARSQECLKPLFPTRLSSYFDRDWVKEGYISQIHDRDDHGQLPSWKRYCYYLAPFLAVATLATYWIYFALRIRFVLAAQAKYGTTYPMAWVFIAVEITVAVPVFLQMIWAVFILKRRHRPKLRLLGDDVPTVDVLITCCGEDVDVVLDTTRATCHVDYPRDKFRVVVLDDGNDAELRQAVENMREIYENLHYRCRPKYPGVPHHFKAGNLNYGLEEVQSMPGGASQFVAALDADMIPESEWLRAIMPHLLKDSKMALACPPQLFYNVPPSDPLCQSLDFFVHISEPIKDALGVAWCTGSGYIVRRDYLQEIGNFPTGSLAEDVATSTKLLGKGYKTAYIHEPLQYGTVPDSYGSHLKQRTRWAIGTVETSFKLKFCLYGEDVRKMTVFQRFSSFTYAVLSLFNIFLLLSLFALPVVLISGNALVAYANEEQLFWLIRACFATLVTNRLCELVLFLPAGYATGQRGSRAQLWMSPYIAFSIIRSFVLPSWLGGQKQAFKPSGSLKSELNERDASARAPLFRRLRVVVWNYMAGFHIAYVYFVLAAVALSTMRCAADGWSVRERLVCLLTHAYWPPAAWIVVVSAFWIPVAYAVDPPAMPAREALLVRDGKTAVARPTPASKTTAFRPQTALFELEYFVSTALTALVFAASLFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P795</accession>
    <name>A0A6A6P795_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative COMPASS complex subunit Sdc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_336611</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dpy-30 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P795"/>
    <dbReference type="OrthoDB" id="417678at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22965">
        <property type="entry name" value="DD_DPY30_SDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049629">
        <property type="entry name" value="DPY30_SDC1_DD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="8568" checksum="1FAF47C5BF296724" modified="2020-06-17" version="1">MPQRRTASPHPGATPSQQQQQAAPAQAMPHGSPTRVYLNTNVTPHLLEGMKLLAANEPEKPLKWLADFLAAKSKEVEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7N5</accession>
    <name>A0A6A6P7N5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GRASP55/65 PDZ-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_281960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7N5"/>
    <dbReference type="OrthoDB" id="3318at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000026">
        <property type="entry name" value="Golgi reassembly stacking protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="120"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="369" mass="39165" checksum="70FB04A79FE841AB" modified="2020-06-17" version="1">MSMFGALNRFISRLDANPEEQKRQGGTHGVSGFQVLRNTNQELALEPWFDFIIGINGRTIDNPDPHLFATEVRNCAGTTVSMGLWSAKGQRIREMYVQVPADSSSLGLSLQWAPLATSEDVWHILDVIPNSPADVAGLLPYGDYVIGSPEGLVRGENGLGELIEDFLERPLRLLVYNHEYNVARPVTITPSRNWGGTGALGCVLGFGALHRIPAPLDEPPQGPGETLFETAPTAHDEKFARPASSSSATHAANRPQKPGTPSFASPPSGDFLVPANMQFKGGDGGGEGGVAPGRGTPPAHKQARKHRAHHNVSPAKGLDEYFKEGEEKSKEQDFAPSGSSSVPPPPKGMGGPPKGPPKGGLPKSAEAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7P9</accession>
    <name>A0A6A6P7P9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_180620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7P9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="22918" checksum="4D1E3CCD42A3A776" modified="2020-06-17" version="1">MCVYAHGGCLACCDQGRCGDYLASLKLDRQSEEQTKFCYVGRRRPFPPHRWRVRSCFTTTHLKIRASPAHYQRPVSANDERRPRRDYQALPPPFSSTKSWTNPTASHSPPPRPRGPRPTPTARTYVCPPYRRGVCPRMSYVRTRRRDKQKGARSALDACGTQRGARGAQGAQEALPGKEARSGSTRAYTRAQRVNVARYMHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8H1</accession>
    <name>A0A6A6P8H1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome-c oxidase assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_334697</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8H1"/>
    <dbReference type="OrthoDB" id="1704689at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003465">
        <property type="entry name" value="PRK05089.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2460204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="258" mass="28882" checksum="1C03B0708FE1F17F" modified="2020-06-17" version="1">MNKPVRALQALRGRGEQWVCSSCSRLPAAAMLLRHAPRRPYSGSSRLMDYVAPTPDQVRAQLRRKNLNGIYYTLSLILGTVALSYGSVPMYKMICQQTGWGGQPINTSHASTGSDPETRLQPVTGAKRLRITFASSVSDVLPWKFKPQQREVRVLPGETALAFYTATNTSDDDIIGVATYSVTPGQVAPYFGKIQCFCFEEQRLRAGETVDMPVFFYIDPEFLSDINTKGIEELTLSYTFFKAKYDREGHLRPVPTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8J4</accession>
    <name>A0A6A6P8J4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_413858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8J4"/>
    <dbReference type="OrthoDB" id="20689at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="62" mass="7379" checksum="01D0518CCA529CCC" modified="2020-06-17" version="1" fragment="single">MVWGFDGKAWWAKGLVGRGERVSLLLLPRSRRRSYDTGVLFFSLSLWPFFFFFPNFVRPDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Z5</accession>
    <name>A0A6A6P8Z5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_335106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Z5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025523699" evidence="1">
        <location>
            <begin position="18"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="103" mass="11556" checksum="56D86FF6DF04D19F" modified="2020-06-17" version="1">MLFWRLFLLCCLRVLGPIGKGGEDERIGSDSVSSLLVWLFVWAHCPFCFLFPLTVMVAGELAGWPADLSASKRGRSWPGHFLFPALAVKPRPPLNRWDRAGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P976</accession>
    <name>A0A6A6P976_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_361449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P976"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="25"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="361" mass="38295" checksum="2B435B02919783A9" modified="2020-06-17" version="1">MARSLSAAGVSAINAALQSAVSGPQGVPGAVVCVVNRDGTLLFSGAAGARDVETGAPMTPDTALWIASCTKLITSVAAMQMVERGKLRLDDADQAEEVCPELRDVKLLKEGEGGELVLVEKTNRITLRKLLNHTAGFGYTFFNTKLFKWSRPIGVDEVGAHHSAINTPLVAEPGEEFNYGNIFEPLGIKDITMFPAAAPAALPNCPNTAQPQIILTQPPPLPFELLATLLNAGTSPTTHRAILTPTSVAHLFTNQIPGMPDFGRRGMPAAKPWYTNVIPDMYPQGAAPQGWGLASFITVEPGPTGRGAGAGYWAGLPNLYWWIDPEKGVGGIVGAQVFPFNDPGVVNLWVNAEVCVYQNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K8</accession>
    <name>A0A6A6P9K8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_167871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="250" mass="27186" checksum="CFFD09310C3BE140" modified="2020-06-17" version="1">MRNIVCPAPRARGANKAVRKTFSKPKQKEKKVKKSGSKCKGGKSSLTGQATGRTRERKIARTSVPVSRPAMLRGSPPEAHAVRARGQRKSREASSTDRRRGTGRGREEEADLPSQARPCLAAWMDGRLSGFVAPRRPRRRGARPVASAGGYETCIMRNTLKRQRTPAPCLPLSMPPARTTSLDSPTAIRTFTDSANARWMAPQRCSPSDYSRPTNCPPFPPPASLIRRDRPATTASGIVPLSHQGLSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9N7</accession>
    <name>A0A6A6P9N7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RING-10 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_336041</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9N7"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12717">
        <property type="entry name" value="RRM_ETP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034931">
        <property type="entry name" value="ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="376"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="409"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="329"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="688"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="588"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="688"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="719" mass="78856" checksum="94E4C10C3091EA01" modified="2020-06-17" version="1">MPSYFFHLGFELYPQPLPDLPQRPPPPQIYLPPPGADIFSSLLPVHSIGSWGATVTPRRRTHHRSKTASASEFDFRARPSLPERRFSQATRSELSEVPKPVARGDQAPKSAVGAKDWRFGPVSIQSIDMEEAHRGKDGSEQGRSRGKSVDHTGPSSSGLTTRGKYIPSDPKNTAVGWGVVHLYREAIDTPGLQDDTTSSSGSDNGKLGDASRMGAFNVADCTTLCILAVPSYMTPSDLLGFVGEQTREEVSHFRLIRTERANKYMVLMKFRDPTNAKKWQKEWNGKLFNSMEPENCHVVFIKTVHFSSADANQDPSSFPHMSNDPFAPSFRSVPTAPLPTSPTSPIGTEHSKSLASSLSTKPLAPPTPALIELPTCPVCLERMDETTGLLTILCQHVFHCACLEKWRGSGCPVCRYTQNDTMLRRGQSADDTTENECSVCGSTSNLWICLICGNVGCGRYDSAHAFAHYEATSHSFAMDIASQHVWDYAGDGYVHRLIQNKADGKLVDLPAAYGNHPNTAMTGVPPDTVPREKLDNMGMEYAFLLTSQLDSQRAYFEGQVERAVDKASMAASTAEDLSRVASGLAAELTAVNARVDESAETIKSLERDLARATARAEKSENLARKLGKDWREEKTVSESLMERISFLDGKVKELGGQVESLQLEKSELEEQNRDLSFFISGSKKLKEEGMGEEVVEGKVEVPAPPQEGSGRKKKGKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA25</accession>
    <name>A0A6A6PA25_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fungal-specific transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_333575</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA25"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="227"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="801"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="803"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2460841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="100793" checksum="A49E79387C2D3C99" modified="2020-06-17" version="1">MTDRTRLSCPECSRSFGRIEHLRRHVRSHGSDRPLKCSRCQKGFYRIDALHRHEQSHVQSALSKGIRACLPCAAGRAKCSGTIPCSRCLSRSLTCQYPGPKHSPAESVSAASSPSQALMPNPTMPAATAAPVNMEGVEENIAGEPTLSHTHQSSLAVSPSVAANIVMSAPNQAPSPNYDLGFTGSAINWVSMDYTDVFNPVSQSNTASSASAGGRATDLRLPIEVLNSPSEQSGLARTPSGSRAPDSTWSMSPPGQFGQRASSRLNVHRQSIPLDFGSGSPTAASQRSHSTGQYYLDGDGSRLPRVRKLKKSNQQQRIQDLLTPVSRLSRTGNQPLGFPMLGRNYEDELNIPSLIDAQTYAVIFERFQLTCGTPNGIFTPFQSTDFVSHEVLDHFVHLYLEFFQPILPFLHLPTLTSSRPPWLLCLAMAAIGSHYADIDCVDRCAVAFHELVRRCMIVTEECQQENFDNILIVQIKLLSAIGMLYCGDEKLASMAPKYHQDLVSFCRRSWLQAAAPFEQFTPWETWQAVETRRRTGYCIWLLDCMFDVHFGLKSILALEDAVVPLPCQELLWEADSSRVWEQLWECASEVPSLLTACQSLYVEKRLQWTMGEFSRILLIHALFHRTWEVETYVRQPLSRWTPTAQPHSHDRQLIQGSSWLPSIPTYTKWRNAACDCLDILHWSANSFIGAASGIEHPTVLHLHLSRVILLTPFRTIVNLACFTAGEPSALCSEAAVSRHRRQIERWATEDQHKARLAMIHAGVLFWHVRRYSAMGFYEPPSVFLASLALWAYGTFASPAVRTASGSDSPPTESDLSEHPTSMYLDRPADDELVQLFVRRGNHMRAKIAGVGHLCSKDGPARVLVEGSKLLEEVASWGWAREAYRVLVKLAEVCRAQQDGGDRSVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAW5</accession>
    <name>A0A6A6PAW5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Putative ubiquitin-like activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_137729</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAW5"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01489">
        <property type="entry name" value="Uba2_SUMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000618">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000002">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000003">
        <property type="entry name" value="Ubiquitin-activating enzyme E1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.20:FF:000005">
        <property type="entry name" value="Ubiquitin-activating enzyme E1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028077">
        <property type="entry name" value="UAE_UbL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF5">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14732">
        <property type="entry name" value="UAE_UbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="14">
        <location>
            <begin position="15"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-activating enzyme SCCH" evidence="15">
        <location>
            <begin position="312"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin/SUMO-activating enzyme ubiquitin-like" evidence="16">
        <location>
            <begin position="441"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="540"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="546"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="577"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF10585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF14732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2461048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="611" mass="68708" checksum="54DF0B415BADB95F" modified="2020-06-17" version="1">MGRDRFARQSLGSLYEHIKQARVLMVGAGGIGCELVKNLVLTGFGDIHVVDLDTIDLSNLNRQFLFRHEHIKMPKSIVARESVLKFNPTVHIEAYHANIKDTRFNIDWFRSFNLVFNALDNLDARRHVNRMCLAADVPLIESGTTGFNGQVQVIKKGQTECYDCNMKETPKSFPVCTIRSTPSQPIHCIVWAKSYLFTEVFGISEEDSPELDNSEDSENREEINKLRQEAKALKRIRESLGSSEFPRMVFNKVFKEDVYRLRGMEDMWKSREAPEPLDYDTISGLTTKIEPTISHNDQVVWSLEENFFVFCNSIQRLSSRLEALKSNHSGDTPVLSFDKDDEDALDFVASSANLRSQIFGIDTRSKFDIKQMAGNIIPAIATTNAMTAGLCVLQAFKVMRNSLDKARMIFLAKSTERVITSEPLRLPNPDCAVCSVTQSRLIVDTSRATLNDLVHDLLRLELGYGDEFSVNNNLGPIYDPDLEDNLAKSFNDLGIVDTSFLTVIDEDDVEPRVNLVFSVANKSIPETSKPIALPEKLDIARKPKQRSQPFPLQLGNGTNDTNGGRKRRASEASFDTEPIKKRGRLDISHPQNPDDVIVLDDTEGGTIVIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAX1</accession>
    <name>A0A6A6PAX1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="4 11">2.7.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_279208</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the APS kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="4 11"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAX1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000212">
        <property type="entry name" value="Adenylyl-sulfate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003013">
        <property type="entry name" value="PRK03846.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055">
        <property type="entry name" value="BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055:SF1">
        <property type="entry name" value="PAPS SYNTHETASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="8 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APS kinase" evidence="13">
        <location>
            <begin position="52"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2460972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="238" mass="26529" checksum="4C97D2CC7D3E0276" modified="2020-06-17" version="1">MATYALPRVPLLQPSISPAEKQTPRAAAPPNRNITWHPSLSRHERNSYRKQRGFTIWFTGLSASGKSTIATALEQHLLHLGYAAYRLDGDNVRFGLNKDLGFSERDRNENIRRIAEVAKLFADSSTIAITSFISPYRADRNTARELHAAATPHGDDPLAFVEVFVDIPVKEAEKRDPKGLYKKARAGEIKEFTGISAPYEAPESPEVHIRSEKTTVEEGVGQIMNYLDKHGLLKLPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB33</accession>
    <name>A0A6A6PB33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RWD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_334113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB33"/>
    <dbReference type="OrthoDB" id="277175at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000075">
        <property type="entry name" value="RWD domain-containing protein (Gir2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="229" mass="26431" checksum="698886EEF24EA6B6" modified="2020-06-17" version="1">MGREEQQEEREVLDSIFPDEIQDVSETEFRISILLDAPEEHDPDAQAPTIQLKVRYPEDYPDEAPLLDINAPPNAPKHKRLDVQEDKARLLDALQATVEENMGMAMVFTLVSALKDAAELLIAERVRAAEAQRDFEAQKAEEEENRRFHGTAVTRETFLQWRERFRAEMEEEARRKQAEKEAEDKKKRVPKEEKKLTGKELWERGLAGKGEEEDDEGLESNMEKMKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB78</accession>
    <name>A0A6A6PB78_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_279280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB78"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025455099" evidence="4">
        <location>
            <begin position="23"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="634" mass="68481" checksum="C311EDBEDBF267EF" modified="2020-06-17" version="1">MRAGILGFAAIALFSVLESCGAVPLRRGNFTTNEPIYSLDDVDNKYDYIIVGGGTAGLTVADRLTEDESKSVLVVEFGDIVDDDPELKMPQKGNPFPTQYMFNISSVPQTALNSRVGTVQISAIAGGGSAINAMFHDRGSVADYDAWVELGNDGWGWNDLLPYFKKAVEFTPPDAFMQEEFGITYNEESAYGGHGPVDVSYPPFQWEGLKTQWDAWGDLGIEAQVEGADGTAYGRIWVPSSQDPVNETRVDAVLAHYKRVAEVRPNYNLLLLHKVTKVELNGGGNKARGVTVESRESGETKMIEAQKEVIMAAGAIHTPQILQLSGIGPSSVLEAAGIDVVVDHPGVGQNFHNHPWFVTVFNYTTNFYPNPDTLTSNETFAAEAYEEYWANKTGPYSLGLGNAGVFLPLSDVTGDYQLIAADYADQAPSDYLATDTPPEVVAGYAAQQAILATLFASDEAAVLEMPLAGGSTSVTPNLKPTSRGSVAINPADPSAEPLVDYRAWTNPTDARVMVEMLKRVREYHAVPAMVEAFHPVELVPGPDVATDDEIEQVMRTQLLDPDFFHPVGTAAMMPLENGGVVGTDLLVYGVRGLSVVDASVIPMIPGTHMAETVYAIAEKVSSVCPLRACIRRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBG1</accession>
    <name>A0A6A6PBG1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_331805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBG1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="128" mass="13396" checksum="0C0D8261E62FC922" modified="2020-06-17" version="1">MNSLGIGIHRPSKKPAGTGSNLTATFIVVLDGGPCVAGGTRPKYGRVSLPRWCAEQPLLGNCKLFTPSHAVAPGKRKGSKPRSAFSSPFLPRRDSFSAAAPAGGAARMQHQEQSGAERCGRARGNNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBX0</accession>
    <name>A0A6A6PBX0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_135301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBX0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="143" mass="15633" checksum="9272D062FD6D1279" modified="2020-06-17" version="1">MTSWAVFTRLKPRIPRSPAGREGTEGSGTSLSRGPWRKAEPKRAAYYYVRIRSRRPCSALRRAGQLMYMRAPAGGLLIGPAESPKTCEPASLSSVRSRYRPSGSAENGAHPSTRGVAETVSLGSLWGLRRRRSCRSMQDAPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCL6</accession>
    <name>A0A6A6PCL6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_93357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCL6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="186" mass="21030" checksum="C88BB029BA803D6D" modified="2020-06-17" version="1">MPCQAIFALLERNCQRLCTVDSSGAFRPHQPHPAETDKTAPLHHVYVLHLRRMPRRMPRSSINAIQSTNSTAASPDDSVFLPSPSSRLSPRTAKAATYGQECPPWAANKPSTKRTSRETFRSLMLPSRMPVMRKRGAFSFSIYPDHAQQFLSEKKKKGNKIPKWKGRKKIKKGSRVGMKKETSDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCS1</accession>
    <name>A0A6A6PCS1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_367969</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCS1"/>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="893"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="832"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="397"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="456"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="568"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="607"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="624"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="664"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1002" mass="101200" checksum="26AC525C356E6BB1" modified="2020-06-17" version="1">MFSNYRDWQIPSPSETPKSASFNNPSLQTPKSATAEPPYPTHFLDAFSTPQVNGHTTPQQTPVQSHFSPTEPQPPSSSFRRSGPKPEDPEFHVNHFNPNPHLPLPPVEPSRRLSSSPGPLASNKRAPEHIGILERGVSKEGAVSAAVTTASGALTAATTMDPSQIQTPPPTRDSSTRRMAQPTVAPGMPLDTPSTVHSKQLATPAGPNGSVTPGFFNQTPFQFPFSPDMAQFQNVGPLSAPAFPQAGRSFWDQSGGNVHAMDIDMPSADDSFGSTQHAGWPSFGGPAGHQFPNQSFQADTPRATHPPASVWASPGPGGLQSPPSFAQPNSSFLSSTTGVDPSMLFSFSDPTDHSSTGSFSARPPSMAPDYMNRQPYEHQTRESNREKEEMARRAREQQQWQQQQIQQQQQQQRQQQVPRAKPLPASAAYPPPPLGQRPGLSRSKTDSGFRPTANNGPPSSRPGSTSHPSHTSSNLPAPPLASTAAATITTATTAAAGIPRRTSPLKRASGSFAAPPAGAGGLSAIPETNAGGGGGGGGGRPKPRTRLVIDETGRAHTETDPADEPASGGAQTQQQGQGQQGQPGQNKRLSGGLWDVDDSSEDDFVPRRGSGSQRGSQRGSWYSVGGGTGGGAGGGGGAGANDDEQQRRATKHARMGSLNSDPNGAAAGTSASASASASTGLSAALASQASLRRPRPASAISLGGGASTASGSGPAGSARGAGPAAMAEPQPQPQPPGFLRKAAPAPGKEVRRFSLGAFGGVSFADAGPGGGATGGAGAGAGGGAAAGGGAAAAAAGCAGGNAGADAQRASPSDAQGALKKVMEGRLRRQGGVFASAPAPPGPLTVSPTALSDPADQVASTPTTDRSGSLCSASSAAAAAAAAAAGGVGAGTTRCVCEGVGSVAKLQLQQQQQQQQQLMIQCESCAKWLHVRCVGLSARALPPVYVCVFCTGQTPAVRGGRVRDPMRGGGGGAGAGGAVQGMGTATGTGYGGSPLAGKAGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD02</accession>
    <name>A0A6A6PD02_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_331733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD02"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="307" mass="34128" checksum="C28700AF490E2C0A" modified="2020-06-17" version="1">MPSTPFKNILIVGAGGSLGSNLLQGLLAEPTFTVTALQRASSKSQLPASLPIITIPDDYPKEQLVATFTGRDVVVNAMTSTAVGEQKRFIDAAMAAGVRHYVASEYGLNNLNPAARSLSPVFDEKGRIREYLMAQEGKSAMTWTAIACGMWIKWSMRHDFLGMHIPERRFVLWDEGRGKLSCTTMENTVLALRRALLKPDETANRCLYVSDFAISQAELFAEIERQAQGEKWTRETVNSEEYIRDAKKRYDHGDMKAVYDLIETGFVTGKYGGHLEAENKLDNELLGLPKNSFEDVVKEGLIAMKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD85</accession>
    <name>A0A6A6PD85_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_330113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD85"/>
    <dbReference type="OrthoDB" id="4074350at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="548" mass="60487" checksum="3EED1C50A6F5CD3F" modified="2020-06-17" version="1">MMPSLSESTLFVPDSACRDQSANCPLPIPGMWRPSESQSRFADQDSDLFPATSWDPTMEPLRLQGQGQLIMDRIQLDQPGQSGFIDFHGVALADNFTVPFPGGAMYTLDVGFFSLYAQEGDRTINWPSGTTGDEIELNRTLPGAFEAGLIPSMSYGLHIGSARPNISGSLQLGGFDSSRCITPPIVTDNRTLTLTNITLEVAEGAERYFGLDEPQSLLDGNGQGAASIEVMPNPGVPYMYLPRITCDAITRHLPVRYNPVFNLYTWNTQSRTFRDLTSSPHHMRFSFNGQNIDVPFALLNLTLESPLTATPTPYFPCSPYEPPDDEEPVYHLGRAFLQAAFLAQNWQSNRLWLAQAPGPDFPPPSVKTLMPDDDTLAGMTNPPTWLDTWRSMLTPLPERNGGGDGLSIGAKIAIGVCAGMGGIALLGLFYFVFRRMRRMRKQERAEEDGAPRKSTSEKEEDDERRGGGITGFFRRRRKSSSASSDQQPFSRGDKYIPSEAISRPQKQPPQRPARPVTTDLRGSDGSDLSGFVFGLEPIDSTRNKETRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDH8</accession>
    <name>A0A6A6PDH8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_332283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDH8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="99" mass="10319" checksum="DD413736DDB68272" modified="2020-06-17" version="1">MGGVLETSAAGVVLAGGGEDECAGGCGDERISLWFFFVFPFLLLFWSHCFVLFCLSLPALSSLLLFSVWVAVALALSPRTCCMGCASLHSGIPNTAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDQ3</accession>
    <name>A0A6A6PDQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tyrosinase</fullName>
            <ecNumber evidence="3">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_389512</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosinase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="3"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDQ3"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041640">
        <property type="entry name" value="Tyrosinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18132">
        <property type="entry name" value="Tyrosinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025631610" description="tyrosinase" evidence="11">
        <location>
            <begin position="23"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="12">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2462108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="598" mass="64952" checksum="B60CE0810384875F" modified="2020-06-17" version="1">MLAFSPQLSSLVALLLFATAFCSPVGSQTRKRQTESHGAFTSPNNETDGFYAIRGVQGSGVQSRYEIRTLQRDHPEMWNLFLLGLQRFMAVDQDDKLSYFQIAGIHGAPWVPWDGVEGEGNLGYCTHGSNIFGTWHRPYLALYEEAVQKHAAAVANEFPADVRATYQEAASRLRVPFWDWAMIPSSGGVLAPSISAETAEVTFTNGSRGTIPNPLHSYAFHPFTPTDFPFYPVTVWPTTVRRPTSPFGANSTSANGEVNADLTGNQESIRRSLFRLFVEPLTFQQFSNKAGGSEVGNLESIHDIIHVSFAAGHMAWIAASSFDPVFWLHHANIDRILALWQAIYPDTYVEPQPQSGSTYAIRQGEVQDTSSDLKPFHATSSGAFWTSTTSRDPTTFMYTYPELADRPSNATLIRRLRSLYDAGSALPGLDNATAAGIAAAPTSAARDWLVEIALPPAAALGSSTYSVRVFVGEPAGADPAAWARDPAYVGLAAAFAGAGGGDAARGEGTVVKTTVSVTEAVARRALEGRLESLEEGDVVAFLRRELRWRVERDFVEVAVEELESAGLGVVVKTAVVKTAAGMGEFPERVGEWRVYEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDT2</accession>
    <name>A0A6A6PDT2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_398236</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkylbase DNA glycosidase AlkA family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDT2"/>
    <dbReference type="OrthoDB" id="415889at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032993">
        <property type="term" value="C:protein-DNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032131">
        <property type="term" value="F:alkylated DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000004">
        <property type="entry name" value="DNA-3-methyladenine glycosylase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051912">
        <property type="entry name" value="Alkylbase_DNA_Glycosylase/TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003:SF5">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="5">
        <location>
            <begin position="105"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2461583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="279" mass="30378" checksum="3A111EA3E3CED958" modified="2020-06-17" version="1" fragment="single">RPAEPHATNATLQTPGGTRVVAYSASDLSTTGGVDGAASGHSGHKEHLPKPTTTTETLLQEAIAHLTSVDPRLQSLIEKHPCHLFSPKGLQDQVNPFQALACGIMAQQVSGAAAKSIRNRFEALYEGEHFPTPAEVANTSLEVLRTAGLSGRKAEYIQGLAAKFATGELTAKMLANASDEEILEKLTAVRGLGKWSVEMFACFSLKRMDIFSTGDLGVQRGMAAYMGRDVAKLKAKGGKWKYMTEKEMVEISDKFAPYRSLFMWYMWRVEDVNLDALQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDW0</accession>
    <name>A0A6A6PDW0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_375898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDW0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="117" mass="12401" checksum="5F2D79B13EEC1AEF" modified="2020-06-17" version="1">MPLQRVPSPTNSSSPLVDESEKASGGYMKTSCEENDERDQDELLRETEQEWLNAVDGTTHVTAASNILDAANGATSRTAESNIADCSGAEIYKTAESNVVDATDGTAESFVISDGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE23</accession>
    <name>A0A6A6PE23_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maf1 regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_258478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE23"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1000.50:FF:000004">
        <property type="entry name" value="Repressor of RNA polymerase III transcription MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037240">
        <property type="entry name" value="RNA_polIII_Trep_MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="294" mass="32595" checksum="31F6E159DCDA0E20" modified="2020-06-17" version="1" fragment="single">QYVSTPEFEFVTGALNFDTADCRIEGGCDLYTTRAAGADKKLYKNIEHTLESQHESILRLSASLSPPQADALAPSLNLSRSSPFGPLSQISSRRTFAYLIATLNASHPDYDFSYTLRPTDFRKERSLRGVMNTIDSTLFNLRPRTSGALLAVPMSATGVQMPGGTSTWGPRMWQLIDKEISLRDCAVYCYSPEEDPMDGEDGAIWSLNYFFFNKAIKRVCYIYLRALSIISHSPASTSKRKKSSRNSLSIGSSAGKRAKYWLGDMAEGVDTSGDWGEEDDDDMVIEEPGDDEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEF3</accession>
    <name>A0A6A6PEF3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_9375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEF3"/>
    <dbReference type="OrthoDB" id="442243at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF1">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="46379" checksum="6C0AD1D686C51375" modified="2020-06-17" version="1">MKKTLLLCFIHGFKGGDDTFGNFPAHLRTLVSQALPKVTVAAITYPKYETRGDLHDCVARFKEWLQNKVIDLEVANGTPSPTVDPSVRTILIGHSMGGIVAAETVLSITSEQPISGSGSFSSDDGPSGFMFPYVQGVLAFDTPYLGIAPGVVAHGAESQWNTASAAYSAYNNVANVFGWGGGGGGGGGNNGAPAAAGSDASARALPAPGGGASSGASGAGGASGGKDVDAAAAPLWQKWGRYAMFAGAAGALAAGGAAAYVKRDQLSEHWNWIGSHLEFVGCLARGEDLKRRLAAVVALQERGALGFADVYTTLGAAVDKTRGGGSATAGAGGGGDSRVAGLFGAQRTFCNLPKGELQRYFIPAKNNKATAETWAHMGMFTPRENPGYFAMSDKAKQLITKWSTNKWYEEAEVDQVTLERKKREEEMADADLEFVEKPDVNAGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEF8</accession>
    <name>A0A6A6PEF8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEF8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="171" mass="19298" checksum="20369789AC947996" modified="2020-06-17" version="1">MTRPAAASKRRRRGARGLECQDEPGRRLSTRCSIRLEHLPSGPGTLRRSLPRYVHAYPWALTHPGSARREKAFRSLTRDPFPRPRRPCLCTHTQRDASPSPLSRRPLAPQTEPDLEAKSHPVTPCHTAPRRAAPRHTMLLLERRGARSRSWECRRPGGPAEMGPWVCVGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEZ6</accession>
    <name>A0A6A6PEZ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_13759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEZ6"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058925">
        <property type="entry name" value="zf-C2H2_AcuF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF7">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26082">
        <property type="entry name" value="zf-C2H2_AcuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="766"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="914"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2462402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1137" mass="127563" checksum="F3904CC7A3CC871E" modified="2020-06-17" version="1">MSTLESPIAKRTKSAFIAFGQLRDALLCPKDNLTVDDVADELDRFRLWAGNIGAAQSLPSRLSLDYRLRDSKTVAAQVLRLLDDLNDSLADACAIVRGERENRHATIDNSEGEFSDEDLEELAFDSEGEVSELRELFLSVKDSTGGLFRLSFLIRKATPRDRYLLASTSTDKRYDESFDIAHVGNKFPRLASQENDWLRIRLGKAITLRREFLRYCREHGEHLKKDDNERAKIDKSKTYQGRDRDTSTAASTFMSVMMKSDTAQEDDFDGNESETSFATSDGGRRDTTRLRVIPLREVKKESAEFECPYCRNILNITKERSWKRHVMRDLKPYVCTFQGCDAKLFPERRAWFKHELEQHRVKWKCRFCPKTIAAFSSRRSLEIHIESHHSGKVVPETLPTLLELCCQPLDRIAASDCPFCGDFEKKLRLTNSRYSAKDIILVSQAQFRRHVGFHMEQLALFALPKHHSEKEEADSNAYTVSIHSKESSEKSSGMELDEGENMAFEEGAVAPKAIGKKQEESERKDSRADGSDFESPGNVPNVDVNVKGNDDADQRELGELEYGHSGPECIPPKLVQATDRGPELDDLDPDDVIPRFRQFIHVGEGEVQNKSSVQQKTSTQTTEKGPSQPTQGPITERQSFIQPFGQKREKFESDSPSAIEEDDEPPLEWRGRDLPTERERYLLRREEKRLLSATDSNRDLEQQQQPQNQHAAGPSTSPPAAIPGQVAAIPSTPADATTAAPRAGPSRAQVMERPRQGEGGQDRVGVSSYWSVGEQAEVERYFSHYGTDWVTIAGLMQTKAPTMVENYYQRKLEKGDRALEQEALAANEKRRRGEDIGPPPVPTHLSTVHRDTSHATHPRTVAPNPAAIADAEAQAGGAASASTSTTQAPNTQFESEAYSHEGGEAEYEYLDLSTVSSGPDKRRGRERQYYPTRDAPRAISGTRELQYFNVAGRPVALPSRRERARYYQGKSIEVVIGSGDRRRRRSPIRYRQEPGISDSNTEVPEESRQAAKPIVRQRQPSIANPPAAATVPAFTPPPPPPSERRGRVSLSPENVDQDEAFVRTKRSDVRYSRYDASGPQVVVAGRRGERSYYEGAEKSYARRRNVVFSDGGGASKIERDRAAKAGIDQEPVTGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PFP9</accession>
    <name>A0A6A6PFP9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L18e/L15P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_368306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PFP9"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000011">
        <property type="entry name" value="50S ribosomal subunit protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="126"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2462203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="318" mass="35263" checksum="0AB06782A484E0E0" modified="2020-06-17" version="1">MPPRLNLLRCSGSLRSPATPVLPFLGPFLPKAQPLRRRLQPRLQLQEQRRAASILGSLSDVRGAYNKRIRRGRGPSSGKGKTSGRGHKGQKQHGKVPAGFNGGQTPLEVYKGKRGFKNNFATEMAPLNVDKLQSWVDQGRLDPTKPITMKELNASRCVHGVKDGVKLLARNAEQLKTPVNIVVSRASAAAIAAVEAAGGTVTTRFYSRTAIRRVFRGEVDPAISLLSPPPMISMFYPDESRRPKFPYRLPDPAGRKDLEYYRDPANRGYLSYMVGEGEGPSLFFKTPQQIAEERRIRMETKSMAVSDATVVKADNRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PG36</accession>
    <name>A0A6A6PG36_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_11927</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PG36"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14280">
        <property type="entry name" value="UBA1_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000175">
        <property type="entry name" value="UV excision repair protein Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.540:FF:000001">
        <property type="entry name" value="UV excision repair protein RAD23 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="146"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="345"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="76"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2462333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="394" mass="41097" checksum="7B1C055B512E705C" modified="2020-06-17" version="1">MKLTFKDLKQQKFAIDAEPSESIADVKKKIHEIKGDGWAPELQKLIYSGKILKDESTVESYNIEEKGFVVCMLSKPKPSSAASSSKATPSTPAPAQSSTPSAPAAPAPATSSGSNAPATPSPAPAAAAPGSQERGFNDPSALALGPEQEAAVANMESMGFERPDIMRAMRAAFYNPDRAVEYLLSGIPESALNEQQPAQPSPRPSGGQAAAPPSSGNTGGAPAAAQGEDAPVNLFEAAAQAGQGGRGGGNGGGGGRAGAAGAAGGAAAALGNLEFLRNNPQFQQLRQVVQQQPQMLEPILQQVAAGNPQLAQLISQHEEQFLQLLSEDADDDAPLPPGAQMISVTEEEREAIERLCRLGFERDLVIQAYFACDKNEELAANFLFDQPDDDDPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKT1</accession>
    <name>A0A6A6NKT1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_174837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001712">
        <property type="protein sequence ID" value="KAF2452295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKT1"/>
    <dbReference type="OrthoDB" id="5412283at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="11819" checksum="2335E358E13FE126" modified="2020-06-17" version="1">MDCGIRPYCADEANSPASDTPHFSAPFAASQQTPWTFNTGSAVDSSDQRLDVDSKLRTEIENNIIIDRPMLFDTFFGQRSQVPVPGIAAAVFDKCMTREPPLYTASDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL46</accession>
    <name>A0A6A6NL46_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_173159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL46"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2452388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="101" mass="10949" checksum="13D5461C53A85500" modified="2020-06-17" version="1">MLVIRHTRQTSSRYSRKRILATTTRARSATGTWPPEKSHADCPKTVDVELPPLVIGVGSQDGSEESHLVEGKDRMGNYVSLSHCWGLGKLTLAATAFVGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLM6</accession>
    <name>A0A6A6NLM6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LDB19 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_294399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLM6"/>
    <dbReference type="OrthoDB" id="3832628at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024391">
        <property type="entry name" value="LDB19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF76">
        <property type="entry name" value="PROTEIN LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13002">
        <property type="entry name" value="LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LDB19 N-terminal" evidence="2">
        <location>
            <begin position="97"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="449" mass="47723" checksum="255866F049489D60" modified="2020-06-17" version="1">MDHLRRHSLTRLHHHSDRKSGTSPKASATSVASGASSGGASGRAATPPTAPAELSIVIESPPVVLYGSPRHSTGALFAGQLVVDVARDAEIALGALELAMVGTVTTRRPVGGAHCPDCVAQSKELKRWEFVGGEGVEGGAPAPAPAPLRLAQGRHTFPFSYLVPGHLPATSAGHIGGIAYKLEARARTTGGEALALERPVKVARAIIPMPENERHSLRIFPPTAITAQVTLPAVIHPIGDFGVEMAISGVASTATSLQNTPQRDASTRWRLRKLTWRLDERERHVSPACARHAAKVGGAGKGMQHEDVRTVGGDEVKGGWKSDFATGDGRIEVAFSARVNPAKKSVCDVDSPTGFVVTHALVIEMVVAEEWVSKKRPNSPTPTGAARVLRTQFNVTLTERSGLGIAWDEEQPPTYEDVPASPPTYNQVRDVDLAELDEEAERLHLAEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM20</accession>
    <name>A0A6A6NM20_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_175743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001713">
        <property type="protein sequence ID" value="KAF2452283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM20"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="246" mass="26766" checksum="DFADAEF83582A48B" modified="2020-06-17" version="1">MLSCVSLQHRLWQGATVNPESKHCHTVAALREDWAKGEGGRGVGVTKLVVPQATGIPQASRRSAKSGCRPASDWAPLLQYHADCAIPTPSRPPSLFPRGQGDAGPRITASGRHHRPRSSQHMAWLAARLRHGRRCWRMVVARQAGAILGSTGRAFRARSPLGAICCSIRISNWARSGAAAHMPVSIANGQKRRRAAPPHEKQEAGTNRRAKSCGQARATRAAGEAIRRVRSQIRSRWRGRPPVEPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NM22</accession>
    <name>A0A6A6NM22_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_311578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NM22"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="467" mass="50289" checksum="7AFB24D3220DB674" modified="2020-06-17" version="1" fragment="single">ARARRRRPLARRRRRQGRRHARAHDPPAQREQRRRHRDNTSNSNIGSNIGSNISSNNSITISSSNIDAKCYRLRRRRSSPPPPAARQRARHERRGRGDAAAVAAGQPGRAGPAAGPEPGAGRRRRRPPALRPALPRAAAPAGRGGTGAARPDGAAERGPLQRGRPAPHRGDHPPGQRDAEPAGRAGEEPRILRQGHDALHRHRGQRTPGQGLRRLGRPGDHHVARLRRGLRHHAPHRHAVRRHRARGGHGQDPGAGAQGGHQDRVRGDAVLLHRHGGQGRRPALRPRHAAPPPGLHRPAPQPPRLRQPQRGPLPARVGDPQELGRRPDERARRVGPQRDRYRCQVGRPAHGGRERRRRPGLVFVGARSRAATRPPATAAAAGPGSSRSSSSSGRRAAALGAGARRRRGEPARPPVVHRGAAEHGRVARRGHQRAERGGRGRESGYRSAVSVGGGLGGGGGGLFGCYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNW7</accession>
    <name>A0A6A6NNW7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_129858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNW7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="194" mass="20711" checksum="73664E4A50D42915" modified="2020-06-17" version="1">MAASGSPPSEAGGLPRDRDPRPCRRGAAPLAVPSLRYHPRRTAGGGGSRGRDLGEAPPAVAPRRPSSSGLHSLAVKQRRAGCQWSQVTTNHRETASRCSSFIGRAKANATRRDNAQLAIARHPPRCDVVIKSEVGTAPRRRGTPFRRSSVHTRGVPAKARLPYHCDVAIKSSRGVGWYIGSATLARCIDNAPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP51</accession>
    <name>A0A6A6NP51_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate kinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_293046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP51"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="194" mass="22015" checksum="A6FF6A67E213E351" modified="2020-06-17" version="1" fragment="single">LVGAPGAGKGTLCKMLAEEYGFRHISVGDLLRQIVLSPNADKKTVEYVRRAELLPTETLFSILKSQFGELNGGRTILLDGFPRRLDQAKSFEEVVSTSRFVLFFDCPEGLAEDRVVQRLAGREGDNLETFRKRFEEFSKLNPPILEYYKSKDKLVVVSLRLEDLPTLPDIGIGRHQRRFKYLVQETAVHDADQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPA3</accession>
    <name>A0A6A6NPA3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Small GTPase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_310169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPA3"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032889">
        <property type="term" value="P:regulation of vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01862">
        <property type="entry name" value="Rab7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000086">
        <property type="entry name" value="Ras-related small GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="205" mass="22863" checksum="FF4A75F4E00F7CA6" modified="2020-06-17" version="1">MSSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSASYKATIGADFLTKEVLVDDRLVTMQLWDTAGQERFQSLGVAFYRGADCCVLVYDVNNSKSFETLDSWRDEFLVQASPMDPESFPFVVLGNKIDVEESKRMISTKRAMTYCQSRGGIPYFETSAKEAINVEQAFEVIARQALAQEEAGDFNSDFPETIPINLEGDRDGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPV0</accession>
    <name>A0A6A6NPV0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ClpP/crotonase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_310407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPV0"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006108">
        <property type="entry name" value="PRK08259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802:SF1">
        <property type="entry name" value="IP11341P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2453402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="295" mass="30709" checksum="CEFA83D2C48AED14" modified="2020-06-17" version="1">MPPFPDPPSPTDPEPTALLVSTDARGITTITLNRPHVRNAVNRALAHKLVAALAAFDAAPSQRVAILAGAGGAFCAGFDLHEAARLGASSASPSRQPWARAAPMGPSRLRLAKPLVAAIHGPALAGGLELALLADLRVCSAHASTVLGAPCRRWGVPLIDGGTVRLPRVVGLGRALDLVLTGRAVGAREALGMGLVNRVVGEMEEGGREGGELVLEEAGRLAGMLVAFPRECMLADRRSVYHGVFEAGTWEDAMRFEFEEGQKVLSEGLEGAKRFSEGEGRHGSFAGGEAGKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ01</accession>
    <name>A0A6A6NQ01_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme 11</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_388097</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="14">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ01"/>
    <dbReference type="OrthoDB" id="10253686at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23791">
        <property type="entry name" value="UBCc_UBE2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000068">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-20 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="16">
        <location>
            <begin position="29"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="13">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00080142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2453472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="175" mass="19021" checksum="C9FD31A5ABE6D8EA" modified="2020-06-17" version="1">MDSSAMAPSGSAEGAKSASMSRSANNNANVTKRLQTELMSLMMSTTPGISAFPNDGNLLEWTGTIVGPEGTPYAGLSLKLSFDFPANYPYEPPTVLFKTPVYHPNIDFAGRICLDILKDKWSAIYNVQSVLLSLQSLLGEPNNASPLNGQAAELWDKDPAEFKRLVLARHRDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQ84</accession>
    <name>A0A6A6NQ84_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine zipper 2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQ84"/>
    <dbReference type="OrthoDB" id="3944251at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF9">
        <property type="entry name" value="CONSERVED HISTIDINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G11910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25010" checksum="EC33B3535AFC9FF1" modified="2020-06-17" version="1">MSDPYNQYPPHYGSPASGQGYPPPQQQQYGGYPDQSQYQSPPPGQGYAPPQGQYGSTAPGQYPPQQGGYSYQQQSPYGADPNQYGQQPSSYSQQYAQQAAGYGPPAQGGYQHGQTPDYYGGAPAAQGQYPSQSPSGQFPQQGAYNQQPYPTDPNNPYGQQQYYGGNPTDPNAPQEGERGLAGALAGGAAGYFGGKKVGGHTFLGSMAGAFIGHKLEDKYKGGHNNGQGRCYKKHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQB8</accession>
    <name>A0A6A6NQB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_374503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2454000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQB8"/>
    <dbReference type="OrthoDB" id="21678at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="269" mass="30903" checksum="14AA9EFD2E634137" modified="2020-06-17" version="1">MATITVGGDDIDFVGLVRNCVYEIYASRTCEEQLAHSWNLLNSDDLIDNIDRVIKGAVEKGRDGSIGDDFKLYVTGYPDFFNIDTDQCSTVTWSWNRNKPGEHQRMTKELRTTFSDMSNQLNLAVIKAVDRNYEKNVYWVDWQASGALDTHRYCEEGIEEPDLQRVVDGKTWFFHYPYNDAGETWLRNLVANLIDPEVETESELEAKYHGNLPAIPTSLINGRPFFDALFEQAANRNGSYPKTKLLDPDRAEVEFSFFRGRGRGCHYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQN0</accession>
    <name>A0A6A6NQN0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_266104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQN0"/>
    <dbReference type="OrthoDB" id="5427732at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="275" mass="28365" checksum="AF593EC69453BA23" modified="2020-06-17" version="1" fragment="single">FRELLNDVPPDSLHAILHEELHPKFKDGVFEHDHSAVELVHSDDPPLATRLITAAKLELAKRQSNNTTPETTTESPPPAETTSEDETPPPASTDSSDDTDDTDDSTTEAPPPPASTSDSDPVVVPVEGSSTEDDGDVVPVTSSALAEAPTSVVVPVTTTDDDGNEVVTSATAPAVEVTTTDEAGNEVTSLSTTVVLTGVSSGQAVTATNSRGRTFVTTYTPNAGVVSSVVYDTTTLPDGQLSTITNFVGVDPQLGTPTGEAGVSVTDEADPSLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQV4</accession>
    <name>A0A6A6NQV4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_374505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQV4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="107" mass="12987" checksum="0FF60383370195F7" modified="2020-06-17" version="1">MSNNEQNNNANEEKRRQFEEMAQEDRRKKAEFDKKQRELKQSISELTQKIAAEENELRQLEADLAAAETETSEFRRQQQALDDSDKRDETDREHELQRMERELDRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQW1</accession>
    <name>A0A6A6NQW1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_354140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQW1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="9266" checksum="A064B1F560087913" modified="2020-06-17" version="1">MRPITWFLGGYSWSPFCALLCPAVFFPYSVPVSKTELVYQSSREPRLPPISVPRVRRVSNLNAGYAAGHHEVHASTEYSERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR06</accession>
    <name>A0A6A6NR06_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_381509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR06"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039903">
        <property type="entry name" value="Zswim2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540:SF0">
        <property type="entry name" value="PHD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540">
        <property type="entry name" value="RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="34051" checksum="3309137D902B93E2" modified="2020-06-17" version="1">MALQPQIPFLGPKLWEAEQILEIPNQAKENIFTCVGFAPTRGRRCQNRIAIHNRVMVRDTLDLASRFDPDNPEVERLLRRVVGRALCFRHVNQEPHVLRNWMDRVEDLAIVRLRAELGQEPAPHEQAVPAAPVQPAPCNRRHARRKPTDDACQICLASTTHTARRHLVWCKTTCGTNYHASCWALWTAAVPALGRGLFCPYCLTAWSGEACEHDIAQAPAGGWDMWTAGNDEEALEEEAGPRLQADGLGFDVLYDPEQHLSMREFMMLLVKSKGVRDMWEMPGVVDLPRVVITLDRRRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRU6</accession>
    <name>A0A6A6NRU6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_353386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRU6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6427" checksum="A79EE4D436A44D2D" modified="2020-06-17" version="1">MVYARTIVLQRSEEPMTVLCTGLVAMVTARSYGAHLLRTAAFLHSIRASMILPPLALAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS65</accession>
    <name>A0A6A6NS65_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA ligase D 3'-phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_387663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS65"/>
    <dbReference type="OrthoDB" id="2588098at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014144">
        <property type="entry name" value="LigD_PE_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465:SF1">
        <property type="entry name" value="DNA LIGASE D 3'-PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465">
        <property type="entry name" value="DNA LIGASE D, 3'-PHOSPHOESTERASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13298">
        <property type="entry name" value="LigD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA ligase D 3'-phosphoesterase" evidence="2">
        <location>
            <begin position="120"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="440" mass="50354" checksum="7D7321F2B446DBAF" modified="2020-06-17" version="1">MGLTDSKRALPEANQIHPLVADTTSSRTDRKQQNTAAAEIEAGRAKIDDYLGYFTRHLATISRSTPPNEPRLSIEGFAQLYLSNQNRHGHHFIIHQHNHPVAGLHYNIRETPYNQLNVDDLRLQFSETSSVSFSVPYGLPGNPNSLRPGRVAVETRVHTMWSHLIETSSKATGSLLIWDTGEYSILPKSEQDVDTDDDSDGKATLDPETNRIPENEKLIHAFQSKYIRLRLHGTRLPEMYTIILRLPRANQLMARKSARSKAPRRVARKSRTDEGLQTTDTEWDEAQNATLQSQKRRKLSTTSTDEMAEIRKKNAYPGAENSIGSVHQRSWYLSLDRWHCGFEKSHSGRQKGRWVRQGFETFFVRGAEFERSVVTGRLSGEVMSDEGVTRFVERKMWRPILECYFRLKQVIANLRADAPLVRSDNFRKLEDIGEETPKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSC2</accession>
    <name>A0A6A6NSC2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_366405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSC2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="203" mass="21547" checksum="E759A1A962290288" modified="2020-06-17" version="1">MARAGAGGGAWPWRRAPGVCWKPRRAPQKTRRRRPHRSPRPTPGAVPPRFIGGARDGGKIASVADRTAALIWRWHESCARPSNFQACPAIAPEPFCTKRCGRYLTSRPPVGRPIRALTAGPVRIVLDLVTGSVQAGFVQRRVVRACAVSNQDFLIEAASASSLLQAAALCVPTPRSPKSNPAAGKPAGAAMVPLHPPPRPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSD9</accession>
    <name>A0A6A6NSD9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_353795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSD9"/>
    <dbReference type="OrthoDB" id="4158258at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="291" mass="31331" checksum="5563F37A06C3EEDA" modified="2020-06-17" version="1">MAETALLVEGACNLSRTSLASSHHTGRSDDLDQSEHMKIGRVLPAGQEATVTHPYPYLFGHSGETASLIPARFTEETMIMVPIPVCELEEPAPRASPPQSEPVGAAEASPSGDVHPRSHSLPFPPDSSGPSSTAVTPPSPRRASVPAGPHTQHQRQQQAPASPRRKSLLHSLSSRLPLPLPGRRSSGGGGDGASSSSSSSSARPLPRDREKDRDRIRMVRMTRGEYLAYWARDARGKYVGTEPRERGPEIWRERLMREKEARAWVGAAPGAGAEDGSNGGSRAGRRLRAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSE2</accession>
    <name>A0A6A6NSE2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_352555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSE2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2454720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="57" mass="6244" checksum="DD6A8C6E60CD716D" modified="2020-06-17" version="1">MPRQSTWVGRGGGGWMEDWIKPELAETIGDDLLATLMERHQLISCIEAFGCPGASPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSJ0</accession>
    <name>A0A6A6NSJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin synthase III catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_291422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001691">
        <property type="protein sequence ID" value="KAF2454424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSJ0"/>
    <dbReference type="OrthoDB" id="5582162at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF1">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="302" mass="33044" checksum="CF2298F27674C70A" modified="2020-06-17" version="1">MSQYGKWFDFCRDSGSAQSTIPVCNLFNESPSRGGSGYDGGCDLTGISLSGDRHLANLGSILLCGIAIAASAYLIWRSERKKAAVGRREIQIFLAAYIIIEICEIFTVGHFPLDGDVRRGFSAVHIATVVATCWILMLNAIIGFQLLDDGTPLSIGLVLLSAAMLFIGTGYIALDTTFSWTGYWDDTLDAPNQAYALYTLYQLVPIVFLFVFYVLEAYLVLRILGEKKPMIYLTGAALLFIIAQIFQYVISVHICNGTDGAINGGLFETLFTLLAVVMVWIFWSSITEDDWPMPVASGGAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSL1</accession>
    <name>A0A6A6NSL1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="3">7.2.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Cu(2+)-ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_352585</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="3"/>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSL1"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0187">Copper transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1054"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1083"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="101"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="193"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="273"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="862"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1154"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00080126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2454731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1177" mass="124449" checksum="309E387F8DB01D94" modified="2020-06-17" version="1">MATTTLKVEGMTCGACTSSVESAFKDIDGVGDVSVSLVMERAVVVHDPEKVPAEKVREMIEDRGFDAEVLSSDMPEAATAATEEEDEGQTEEEDGEGGSLFVTELSVGGMTCGACTSAVEGAFKGVPGVVSFSISLLSERAVVEHDAQLLAPNRIAEIIEDTGFDASIIDTKQAPRKIAPKKSRRKPSSAPTVTTTVAIEGMTCGACTSAVESGFKDVDGVVQFNISLLAERAVIVHDPAKLSASKIAEIIEDRGFDAKVLQSIESSASAAVSTAHFKMFGMPDAKAAMDLESSLKSLPGVTAATVNFGTSRATISHKRASIGLRALVEHIEGAGFNALVADAEDNNSQLESLAKTKEIQEWRNAFRTSLCFAIPVFLTSMFFPMCLRFLDYGRFQLIPGLYLGDVVCLALTIPVQFGIGKRFYISAYKSLRHASPTMDVLVVLGTSTAFFFSCAAMIVSIITPPHSRPGTVFDTSTMLITFITLGRYIENRAKGQTSKALSRLMSLAPSMATIYADPIAATKAAEAWNNQEVKVSGESSLDSVEQKTIPSELIEVGDVVILRPGDKIPADGTIISGESYVDESMVTGEAIPILKKHGSHVMAGTVNSAGRLDFAVTRAGRDTQLSQIVRLVQSAQTSRAPIQRMADVVAGYFVPIIITLGLSTFVAWMVLSHVLADPPTIFMDEESGGKLMVCVKLCISVIVFACPCALGLSTPTAIMVGTGVGAENGILIKGGAALEKATKISHVVLDKTGTLTVGKMSVSETSLTKDWTESPERIRLWWTLVGLTEMGSEHPIAKAIVLAAKEQLGVGPEGSFDGSIGDFEATVGKGVSATVEAAMSSGRERHRVVVGNSSYLRSQGIEVPASAEADPKSALTTPTTPTAPRRPHSGKGPSAGTTTIHTAVYPNYTGTLALSDSLKPAARATVQALARLRISCSIVTGDALEPALVVASQVGIPPENVHASATPADKQRIIEELQVPTAQGGPGELVAMVGDGINDSPALATSAIGIALASGTDVAMEAASIVLMKPDDLLSVPASLHLSQAIFRRIKLNLLWACVYNVVGLPFAMGFFLPWGLSLHPMAAGAAMACSSVSVVASSLALRWWGRPGWMRVAVLDPAAGIDEEVEYNVKPSHRPGLVHEWIVQAREWMRGGKRNRRGEDDRDGVGYVPLRDMGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTY1</accession>
    <name>A0A6A6NTY1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_365796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTY1"/>
    <dbReference type="OrthoDB" id="3542212at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052:SF1">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19293" checksum="60CAFFDA1CC248C0" modified="2020-06-17" version="1">MPVLELSLLRLLVPPDSSLLSTLSLARSAVESFSTFPNTFRYLVSPPPSVGAPPTHIYIFGHWASVAQHFEDWIPSEANRSIMAELKHKVVVEWLVHVEGGLEGLGLELGMGGLGNGEEKSGEKVRVARYVVKEGERAEVEGLLERLGVTGRWRVDVEEGALEELDLMDWNEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUI6</accession>
    <name>A0A6A6NUI6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_365595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUI6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="160" mass="17208" checksum="328A9639D642980C" modified="2020-06-17" version="1">MAYRKEVSVLALAEDRRSNRREGKRLTAQGARVAHATETGLFAAPWARNGGDLGRKERDACRGQERKSRGPRWKREAAGGANERASAPRCRERQALAGRAAATRGTRSRRAPKSEGGFRGVVVPDPAATGAWKPVGPRESGAKRAERGRAARAAGPNSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUP0</accession>
    <name>A0A6A6NUP0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">GPI ethanolamine phosphate transferase 1</fullName>
            <ecNumber evidence="14">2.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_80364</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="14"/>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUP0"/>
    <dbReference type="OrthoDB" id="2748310at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16020">
        <property type="entry name" value="GPI_EPT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000015">
        <property type="entry name" value="GPI ethanolamine phosphate transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007070">
        <property type="entry name" value="GPI_EtnP_transferase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017852">
        <property type="entry name" value="GPI_EtnP_transferase_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037671">
        <property type="entry name" value="PIGN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04987">
        <property type="entry name" value="PigN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="674"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="739"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="777"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="802"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="882"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="921"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="956"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="987"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 1 C-terminal" evidence="16">
        <location>
            <begin position="483"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="711"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="713"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2455152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1063" mass="115408" checksum="F22DAF48518DEA69" modified="2020-06-17" version="1">MARLSRHGFLAIAVFFHLLYVYSIFDIYFVSPIVSGMRAFKVETEPEPPAKRLVLFVGDGLRADKAFQYHPDPSPASTDDAYAAASPRPLAPYLRSRVLSHGTFGVSHTRVPTESRPGHVALIAGLYEDVSAVTTGWKLNPVNFDSVFNRSRHTWSWGSPDILPMFAEGAVPGRVDQDMYGAEAEDFTQDATSLDTWVFDRVRQLFTEDTRKNVTLDKELRQEGNVFFLHLLGLDTTGHFYRPYSKEYLHNIKVVDSGVQEIVGLVEDFFDRDGRTAFVFTADHGMSDWGSHGDGHPDNTRTPLIAWGAGVAPPVLVPEGQVAPGHEDGFSADWHLDRVQRNDVAQADVATLMAYLAGLEFPVNSVGELPLAYVAAGVRQKAEALLVNARQILEMYAVKEAQKQAHVLRYVPFPGFREDGENGGVGGGSSSNSANASASEQQLALQLSAVERRFAAVRDAIDNGRYDDAITQSEDLIQLALAGLRYLQTYDWLFLRALVTAGYLGWIAFATATVIDLHVLQEADAAAPIRRNPAVVGAFAAALAALFAALFIQQSPWTYYAYAVFPVAFWEEVLARREALVRGSAALLAGVQSGKQCATLVAKTVAFVALLEALVASYFRREIYTACYLAGAAWPILYGVLFVKSNPVLVATWMVCCVLMSSFTLLPVVKVESITQILLGGFLMFAVGAAYLLFEKSILVQSEAGAGGVMENGSKDGKTKSDGRKGVGEGLAASGPDGVSRSIIGVQIGLVALAMLVTRSSVASLQAREGLPLGTQIVGWIVLVASLTVPFLHGLRPNNHYLHRLMVIFLSFSPVFIILTTSYEGLFYFSFCATLVTWVRMEHRIYTYTSSTRVPNTTKSTTDNTATGGQKFRPLTLADARIALFFLYLLQSAFFSTGNIASVSSFSLDAVSRLIPVFDPFSQGALLMLKILLPFAVISANLGILNRRLGVAPSALFMVVMAIGDALTLNFFFMVRDEGSWLDIGTSISHFCIASGLSVFVAGLELVSEVFVSGVEFEGGAEMLDGKRDGRAEVSDSNGSVRVKWEGDGIGGSKEVAANALDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUQ3</accession>
    <name>A0A6A6NUQ3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_373120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUQ3"/>
    <dbReference type="OrthoDB" id="6129702at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140278">
        <property type="term" value="P:mitotic division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11889">
        <property type="entry name" value="SH3_Cyk3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000168">
        <property type="entry name" value="SH3 domain protein (Cyk3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.620.30:FF:000005">
        <property type="entry name" value="SH3 domain protein (Cyk3), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052557">
        <property type="entry name" value="CAP/Cytokinesis_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035553">
        <property type="entry name" value="Cyk3_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056409">
        <property type="entry name" value="Ig_CYK3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333:SF2">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24584">
        <property type="entry name" value="Ig_CYK3_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="536"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="623"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1115"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="486"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="590"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1118"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1151"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1251" mass="134825" checksum="7BB4F8F4EE2619DE" modified="2020-06-17" version="1">MAAAPPLPTRFPCWCRAVYSWGGETKKDLGFIEGDLIECLNAGDGAWWMGRLKRDRRMMGLFPSNFVELLEDDFQPESRSVSPMPGTMHRVGSSISRAASPAPQSLQTPTAKPAPKQKSKFRKPFTAYAAAGQPNPAAAARETVRRQQGLNGTPPGSMNMHRPYSSMKRTSNESRVSSPLPHGQGISQYRATSPVPSRGNSYNSRSRAPSPAPSHFRAVSPAPSVHYQSHSRAQSPDPFVDDASPPPPAPPPHRVAYAQSRAPSPQPYHDDYRGQAGHHTPEPPRSPNPTGGGRKAHTPSPLTSAYNDVMSSLEGMTMNSRHSPELPGPSTPPNIWSPEAFDELYTKRRIPDRGNRPFTSIGIGGTSLDDEDQDNSYEDNSHSHQVQRGGGGGYGGRDNNQTPLVSNYVQRMEDRLRRLQEEDNRFQYDRGPAVPPKNSPHPSRPGSPRTSAREAELERQRKLNNRKSAFELSGKAGPGRTFTTKSTVTNASSTAQSTSTNGTNSTHVSGKSIMSGQSAGAFSATSAGSYARHKWARGAGRPVSVMETRSERPETPHTGITYHSSHDSNVAQRPETAMDFNTSGSANVGNGLGESNGGLGGLVAPKPKKSGFFKKMIESAKTGAASARSTISSNQGARPVSRQKNLLPSGLTGIAGGTAAATTQSSAARDMGLGGGSNIDWIQVRRDVNRSNSLSATEIHERIERCQMLDLTSIRPIDILYETAEGDEGLDGLPIAEATDFSVCNLSLVDKSARFVTNLPHVVTAASLAQGYVCRPYRSDVQRLRAIFTWVAERIAWEEDFEGPVDTRRVLQTKRGCSEEIAVLVMEMCGAVGLHAEVVRGYLKQPGEPLGDVEATITRPNHWWNAVIVDGEWRIMDCALASPTNPKRVFYSSASAHAADGFYFLTRPTHACFTHVPLLPEQQHIVPPVAPGVLLALPCACSPYFRHRLHLAEFETSLLALENLEMAHVYLEVPEDVECVAEVEARAFVQDQDGDFLESGDVVRKRALAQAEWLVDGRKRYTVKALVPGDEGAAVLKVYAGKRGMMTSIKSNPHPLALAMPLTHTGTNPPYDFLVLHPTPHAQRHDLYVAQPQCARIAVNNTFVFTVRQHPASLTATSPNPAASSNHGPAAAAGRVSPNPLNRPASALSMTSNSAAGSTFSAGSSAATGSNSSGANGAGANGAGPPKPAKLAIQQPSGKIIRLMRKPDVPEGVASTSWETIIKIGERGTWRGLVLADRSARWCVFAEWECV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUR1</accession>
    <name>A0A6A6NUR1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_67242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUR1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20095" checksum="BE33311CC37D57D4" modified="2020-06-17" version="1">MMKARKINVATCGACCRELLPIDGRDAPFPSHSTPSPSARPPARRTCRGLRALCLRSQQFPLACRQNLQRRRDRRPDPGHRRADAMKFAKTRARTGPGMAGQVPQLQARQEAPQGSRPRPPHRPLLRQSHPLVRLRRQPLPLRLVPRPAPRRRPRLHALAAPARRVDAALRHVQLGGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUR6</accession>
    <name>A0A6A6NUR6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_395606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUR6"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="53077" checksum="8FF9C28DB351FB55" modified="2020-06-17" version="1" fragment="single">SPTSQFWIEELSFSILVLRPKSTQIHTFPSFLKMRRKFLLFPLLAHLVARPIQAQEDENTDVQDLIDGAVSLFTEATSVLGPVYTQVVDEAQSIIDAANSQNAAASSTTSDAASSSATEASSSTTASASSSTAAESSSLTFPSTLSISSSLSNALPTSSSTAEDDSSDDDDDNNIPIIVGTVLGAVVLALLILLVWLVLRRRKNKKRGGYTTTNSDIEGWNNATEQPDMAATHDARLHSQLMGRDPISGAPVAPAAAATAAGAGLGARHHHRHQRSGSSLDEPDLADHPAFRNESTTSSSSRENPFTPVPPPPRRMAAPNSRPGLTDGMVPGQEPYLSGGANHGSGSGSNNSAVPLMWSRGSMKGRFGRGGGGNPDHGAGGAAAALAPSRTIARKPVPTATAREMAGDEEGDETLVEDYPPPRITTAVPPAVPDRSPKRGHSSRGSFEQLDQPRERFSWEEEDDELTDLQPAGYRHRRGSSNGGWTPVGYNGDRTNYVGHAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUS8</accession>
    <name>A0A6A6NUS8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_289205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUS8"/>
    <dbReference type="OrthoDB" id="4851849at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="641" mass="71833" checksum="7D0DCAD3129BE303" modified="2020-06-17" version="1">MHSLPITGTVRDRFVEVSALLYQLDPVRGEPTAHDLDQELTHESGMLKERLLKRKFLNSFALICATKKDGPSVSAACLEEGFPDGTVVRIASNSGVCDTVLLQLQQIVTILNQVADRVLHPSAGVADVFQRIVTLDRTNIWLYLKDIASSQQVSNISIEAVEMRLQEIESSTPAGLFARVQFVEWLKQLLEVKDIKPNPGLDSLMGLVRWAQEARQYSELIGHIFSMTDCDLPRWLSSIWKLGRYGVASKALVRLASEFPSLFNPMRVESVVAPQAIPYKATRESPLRSVLKRVVGHRTDDYISRLRAVWNARNPETEFRNVCSLDLVVHAEMQLLSFYDHHPERMPNFRFIGVSKKSCYLCHLLLAAHPNLFNVSSCHQKLYPRWIPPISSDPTIYRRYRNLTSNLTKTMESIAKQELEGRLGAPRRAAPADSTGGPSLSDSRTPAVIGAATSISVRSESPPVYREDDEMGGVAVKQDSDQLMSSSIEVVELSRTSMDECELVGSVPDTQMSDLFTSSRIVFHFIRADDMSRQDIICMGDITCPSTRRPSWEKLIKILADDSDFGLGFKHGQDYFMVNGRIRVGSERQFLACLQYLYNMNNWSSEALVYSVKIQDATPVHSRAPAATEPRDQIVSGVPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVW0</accession>
    <name>A0A6A6NVW0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_288948</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dual chitinase/transglycosylase that plays a role in cell wall architecture. Chitinase and transglycosylase activities are coupled. Required for the polysaccharide cross-linking at the septa and the cell wall. More specifically, transfers chitin to 1,6-beta-glucan in the cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVW0"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000152">
        <property type="entry name" value="Cell wall glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF27">
        <property type="entry name" value="GLYCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025638091" description="chitinase" evidence="14">
        <location>
            <begin position="22"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="15">
        <location>
            <begin position="9"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2455910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="270" mass="28923" checksum="3A689E0EAE8F286E" modified="2020-06-17" version="1" fragment="single">MRSFISAAAGIAALSFPFVHAQTFTDCDPTQEDCDNNPGLTESPLVCDFAADGESAFQGWTATAGALTYGSDGAEFTINQRGDAPTIQTDGYIFFGRVDVTMKAAPGTGIISSIVLQSDDLDEIDWEFIGGDNANVQSNFFGKGNTTVYNRGGVHPVADAQGTSHTYSVDWSQESMKFLIDDALIREVPFDADIALGGANYPQTPCNVRIGIWAGGDPDNSQGTIDWAGGETDYAQAPFTMTVQKVEITNYNPAGAYEWTDRSGSWESIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW71</accession>
    <name>A0A6A6NW71_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">tRNA-guanine(15) transglycosylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_271509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW71"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="6">
        <location>
            <begin position="14"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2455513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="473" mass="49689" checksum="9B962501E786E2E8" modified="2020-06-17" version="1" fragment="single">FTVRKAAAGATIGPRLGRLTQAGRGRNLDAGIETPNFIAVASRGVVPHLTPDMVERHTGIESVLMGLEDFIEKAPATTPPILSSALTSHASHTSPSSPSPLHLFTGTPSLALTVLSARRLPPVPCPPTLPNSDAAIGIHTSVGFRSLAAADYARAVGRLGPDVVVALADVPFGAERVSVRRREKMAERTGRLVGGLVEELGRRAAEGAHAASSIFAPVLPIPLAQQRFYLDELAELASPFSYASTPGISGLALYDPSVLAPCPAPTDHHDHALTLPAPLTSLPRLSLAPLPSPHALLRAISHGADLLAASFVSRATDAGIALDFSFTSSARAPSLGDPAAKTTPRPLGTNLWDDAADPPHATSLAPLAPGCRCYACAAHHRAYVAHLLRAREMLAWTLLALHNAHVLDAFLRSVRASIARGDFEADAEAFAKAYNEEGWPEGVIGAEGPRVRGYQVKSGRGEPKRNRKAWGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW82</accession>
    <name>A0A6A6NW82_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LPXTG-motif cell wall anchor domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_373059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW82"/>
    <dbReference type="OrthoDB" id="5369729at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="742"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="899"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="860"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1114" mass="116277" checksum="F22D27FBE860341E" modified="2020-06-17" version="1">MALHPPASPLRQRGQHRPLQQQQPPPQHRQPPALGRPSQLPQRTEPAPRPSTSSAALGAPATTLRGPPSPPRTAAAGSAARPRTKSATTACSAAARQPTISTSVSASITTTAAAAAAKSRPSLASVPAVAAALAAAQPRPRTASALAPAPARPPLHHKSPSAPSATTTTASTATTSTATTASPSANSPSTPGTSAAAPEPRSPPSKRPPASRSSHGIETTHGPPPALITRGSYSVDIARRADLARAHQQLNELGLAAVTRRRSSSSRDRSRDREADARSSRAAALPSERSPRSSRSSRSSRSSRSSRSSHRGSAPSSSNEGAISAAAAATMDGRYRGAYADYDELNGSRSDPDSLTPDDSPVLEPEPLMDSSGSGNSYSPGKSEKPSSEDLFLKLAQDGSQERLHDELNERQGSRLSEAPQRQSYPSSYSTSTARPSSRDQVSMTAGETRLPGTRRKSAASAMPRPSLRDQSPITPNHASFDRNRFHGSNHASPSFTSREREMSPEVSHLTRRRPSVSGSEYTPSSRIQAFRSSNLHYSTPRDYVTPHIDTPPDANGNGRTHSRAEGSESVDSATAPSTVWDELDELKSRIRKLELTGKLPPSSGAAISNTSGDRPRTATTTVTTISSSPKHYRKPGSSPTASTVGGPGAANIHPTLHSALAKAKTLLSPSVYRALEGTVSDALELAAMAGNTGPTGPNYSASTVVNGGGLPDRLVRRKADNICRGLTELCIALCEGRSAPELGSPGLPNLTPDGRRGSMAKGPSGGSSHLPSPRNFQHDNQTQAGADGADDSLTTYAGSGDFELEERPRAPPSRALTRIEARRTSLLGLSPNNNSPRETSAAAAAAATNTLSQSQYHSPPIQHPAFAPHQQPQPQPQQHLSQIPSRFARVGTSLLRTRREKNAEAQAAADDSRRVGGRGTTDEDDSTLRAPSRAFTAIDALRAGQPARSRSERVSREYTSKHPLPAASPLVANAAGLRRNSGVVITGGNNNGNSNNYNNNNSSSGGGGGPSNGSANDGRYQPATLPARVPPAEHTALHKDPNGRRYVIDRSSAPPPETGVGANGHQAAGGGGEASARQRFGGFGQYSAGARNVSAGLGRSGSLGRKTRDLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWG0</accession>
    <name>A0A6A6NWG0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_323151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWG0"/>
    <dbReference type="OrthoDB" id="5226580at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="94"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="194"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="722" mass="78851" checksum="D7986DAF3DDBC5E1" modified="2020-06-17" version="1" fragment="single">MSDQQTAPSAAAAAASDDNFASAAVAWLGTPDSKSTSNSPPDATETSSSRDRRGGSGGGSSGAPRRQASTGGAGAGAGASSSSTAAAAAHAARHNSSQACTSCRALKVRCLPAEAAGGSGAERRCLRCARSGRSCVFAERKKKLPRKRTDTRVSELEKQVRALESLLRQGTVPQQQQQQGRGGASHQQLHHHQQGLQQQQHQQGLLQQQQQQQQQQQQRRPGAPAIGAGATGVAQQGASDDGGQEMSQPMVGQAPGGSDFTSTSQQQQQQPHELRQSSVSSSIAGLEGNLDAPDVIDRGLLSIEQAEALLHTFRTHSAPQMPFVEIPPTWPVEELRRRRPLLFLSAIMASSGQFDQNMFHDLSKEIAHIFARRIMVEGDKSLELIQALLISSGWSFAPDKFEELRFYQYINMAGTLALDMGLRDQPFDSNVLGGYSILEAKRTLVACYLCCSSVATSMRRPTMLRSSSLSIEFLKELENDPEATWIDKVLVAWMRLQRTAEEMSVLIGLEDSNLPLDLDEPRVQLALRSFNQQTEEIRRSLPPEIIDTNLEISFHVNYIFLHEVALYCDHDASDFRPPYRLRAPGAFRRRQSMRPLGLSYVRAVNTIVSHAHSVLDVFLSTSVEYCRASPTVLFVRVSYAFIVLIKMLSSACSRMANLSQVLDPETLRVSEYIERVIPFLARISVEDGACKCRAASKFLLVLTRLKAWCLRHSAGGSAGLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXY9</accession>
    <name>A0A6A6NXY9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_49968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXY9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="20681" checksum="CD51475C1C4D45AC" modified="2020-06-17" version="1">MRFRIETRQLRRQDSESTFETIITKANKISAPLNRPIVCFPLLPDKGQNNYICRSDPLGSSHCRFYRLLTLTCTRKQASITRMATRLYRQKPRAISTPKRTKLRPALTETGQQNNNKRRTSKQIRKALAGITEQLLLGRQLNTNNKCNVVVKKESVTKKKKKIKKIDCPCFMKTPEDAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY20</accession>
    <name>A0A6A6NY20_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_50951</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY20"/>
    <dbReference type="OrthoDB" id="18302at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF15">
        <property type="entry name" value="SPORULATION PROTEIN RMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="437"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="652" mass="70610" checksum="1F6C5C5229B2E434" modified="2020-06-17" version="1">MASPAPSAVSESTPLIPPSPSARSRPQPTPRPPRSVTFNPTVTSASPNATASPLRPSAQLPPLVSPRLTRQDTGLPTASGQLAGAGLQQGYQTVPSHPHGPGYGTAAQQHLHPSHAPMLSALNSKLRRRNSSGSALTPSSTMGPAVPSVKIGPQRTTRTAQKLKLLPSPADAEAVGKVVGAPATVSGDEESDGGRDVYTQFTRITDPTARRDAARLGKADRDRLPRVTAYCTAASYQTDELVRYLKGKGKLRGAQPKLFDECVYTPWRYGKPPGARERSGSGSSAGDWGSLSDWEREERRRERVPSPTLAAALSTPFVQAGGATGQERRFSDSAVEVENHNEQRRDDLIDLHASGGGGTGAPSGLVAASPRPTSQAISSPPGLRQSQPLSPPTAPQFQPLPPPATPPMQPLSPPAPAAGIRSSEAANFDVEVHTPEVFLFNYGTVVIWGMTRSQEQKFLKEITKFEVEKLAKDDIQTEDFNFYYTREYQARIYNDFISLRDKKNYMTKLAISHALAQSVKTSLYEDLVDNTIEVTKEIPSQIAMTGKVNLTRRQINMQIGELFILRINIHLQGSVLDAPELMWAEPQLDPVYQAVRSYLEMDQRVGLLTERLDVIADLLAVLKDQLSASHGEYLEWIGKSALLGMLSIATVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYJ8</accession>
    <name>A0A6A6NYJ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MEMO1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_386248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYJ8"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2456830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="332" mass="36323" checksum="1264C3951401C139" modified="2020-06-17" version="1">MVVRSATHAGSWYSASKSELSPQLDRWLDQVPAETQCIGADSSKEDAVALPAQGARAIIAPHAGYAYSGPAAAWAYKALDLSNAKRVFLLGPSHHAYLTNCVLSRCDAYSTPLGDLRIDKDTVAELAKHSQFQHMSRSIDEAEHSLEMHLPYIYKVLSRQFGDPSAFPPLVPIMVGSTDGDMEQAVGQILAPHLADPTSVFVVSSDFCHWGTRFRYTYYRPTGAAPRNSPPSGPPPTSPPIHQSIANVDMECMVAVENGDHDEYWSVLEETGNTVCGRHPIGVILAAVQKLREEGTLDKTKGHFKFVRYERSSLVETIRDSSVSYCSAFAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYR0</accession>
    <name>A0A6A6NYR0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_372514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYR0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="59" mass="6342" checksum="F84A6E7C0CE2E2D5" modified="2020-06-17" version="1">MDSPDKALSDKATAGDESGMSDGTKIALVLGFLQLICEIVAIVQRFHPRERARGDSPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZ59</accession>
    <name>A0A6A6NZ59_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Succinate dehydrogenase assembly factor 2, mitochondrial</fullName>
            <shortName evidence="4">SDH assembly factor 2</shortName>
            <shortName evidence="4">SDHAF2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_286834</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the flavoprotein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SDHAF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZ59"/>
    <dbReference type="OrthoDB" id="284292at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.250:FF:000002">
        <property type="entry name" value="Succinate dehydrogenase assembly factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="entry name" value="Flavinator of succinate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03057">
        <property type="entry name" value="SDHAF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028882">
        <property type="entry name" value="SDHAF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12469">
        <property type="entry name" value="PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12469:SF2">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="YgfY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2456797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="292" mass="32579" checksum="29359BD8B3F6A54A" modified="2020-06-17" version="1">MSSVLRVWRSATVARAVRANCQRSLTSSTARFADLNDRTNDNSEAWRKAQKEKPLNPHMTNTNSTISNNMPKLGEDHAPPELLSSTDPNFKPSDTNPENTERMTGGTQKSGSEAAAGELDVGEMEGASFKVEPIRREGEDPNTMKARLLYQSRKRGTLESDLLLSTFADAHLGNMTHEQLRQYDLFLDENDWDIYYWATQEPPATSAETAEGGDSTMASSSVLGKGPTEEADWKRQPPSGEWAQTVGNFKPAYRPVPKRWKDSEVLRMLRKHVKESHSGGMAFMPGVRNFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P034</accession>
    <name>A0A6A6P034_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_421770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P034"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="167" mass="17393" checksum="25AC994C8580A2FF" modified="2020-06-17" version="1" fragment="single">VAAGCLRRAARLVPTAAALARVAAAAGGQHVPRRAGAPQLAPAAPARCRRSAARSAPAKSRSSLARRAGQAGLRAFSFAAELVAHRSGCQRSLPARLQPEPAPTAVLNRVLACISRPCPVPLFPFRSWLLLVLLSSFTLRPPPRCASLPARARTPPPTAPSPPVARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0I0</accession>
    <name>A0A6A6P0I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_392595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0I0"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="656"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="789" mass="83794" checksum="F34C9E11B38FB7CA" modified="2020-06-17" version="1">MAKRSWSLANSAADETDHATSTPPRLFNGGGSNGTKHGTQQPYVPRVSRKVKACAACRKQKIKCLMENGPPCRRCTERNLSCVLNKSLQTLLDERSQWKETVSHDLDHMHSALQGVLKHFSLPLLPPLESHVLDSDDLEVSDDIFDQPAEPPPTALLPSCDSSPRILLQDDALPNVPIESLYQITRPRSLGGEVSDDDKYLSPASANRDGSISGGPGSQGSDLGPIGGVPSNSFSADLVSKSLLSSAEASRLVDLYLGRLDHFMYRIGGAGHSSLSSLRGGGGGGGGGSGDAGSSPILTAAMCTVAALHDPASNHLYESCSSEFRRLLTASMWERGVDKAHLRAMCIGSYWLSDISWTLSGAAIRRAMEVNLNANLYRLDGVDCSIAAAEDAADCLRIWYILWICDQHLATLYGRPAIVREDYSVKGWERLLRSPVATEDDRRMISQVALLNIVAKVRETFGPDKGERVPVTYAGMIADFGRQLDRWFAVWHADLKGEFWMQHHDYIGRFPRRGVQLHYHFAKLHLYSHVFRGLTSPSSYPAPHSTTTFHPFASAAVSSATAILNLLLTDADAGASLAGVPHYLHTMSAFACVFLVKLAAKFPPASTATSSSSSSMRVVGLFRQTRVGRAHLVHLMADGLEKLAVGLLLVRDGSGEDAPGAPLGGPMQPPPAPPPGIDLDPRLSVAHPHAHAHAHAHGVGSHPPPHADPAPLLDSPFQAFFVDSSDFGFIAPAPGGGLGGGPHASSPAQAAAGGSYAAQGAGHGACDGGAAGGPAASYFDLGFPAFGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0K2</accession>
    <name>A0A6A6P0K2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_286048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0K2"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="206" mass="23583" checksum="BDA729E8C42263EA" modified="2020-06-17" version="1">MSLQLARAEKADIPQLVDLYFNTFKSPLVLRVKPDVPPVREWYKKSLESDIEKPYTRIYKVVEGQAGSVQASVEIIAFAKWSSPHTEPPQEKFTEWPVDGDVALFEEVTGKATEKKEKIMGQEEYWYMGVLATLPKHQRRGAASLLMTEFCKQADQARHRSYVEASPLGRPTYQRFGFETQDTFSVVIDGEPYIDCCMVREPQKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0P0</accession>
    <name>A0A6A6P0P0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein gyp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_263580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0P0"/>
    <dbReference type="OrthoDB" id="26371at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000007">
        <property type="entry name" value="TBC1 domain family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000037">
        <property type="entry name" value="TBC1 domain family member 22A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000001">
        <property type="entry name" value="TBC1 domain family member 22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF26">
        <property type="entry name" value="LD44506P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="243"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="575" mass="64147" checksum="4353215D5578455F" modified="2020-06-17" version="1" fragment="single">RPRSGSPFWRTNSANTGSKNYDGKKVVGASYSHADMLKFDSLSLSGGSSRPRTPPGPSRETSNTSNRSGNTSTGSPPPRRTYTSFLRETNHDWDAQDEEEEDNGESEFNLEDDDEDEFGLPSIASMRRKGKRLNAAKANVDPGGGPYYGNSSSGGDIAEERGIPSYPTAKRAEGKILRPQYKEILRDPANALHLIDHPPLPAGASAKEAEAYSSRIGRINKFKRLLQTSSIPLAELRASAWSGVPQEVRAMTWQLLLGYLPSSSERRVATLERKRREYLEGVRQAFERGTAATKSAAREGEGGTGAQTPPVAARAGTARGRGLDEAIWHQISIDVPRTNPHLPLYSFEATQRSLERILYLWAIRHPASGYVQGINDLVTPFWQVFLGIYITDPNVDSGMDPGQLPKAVLDAVEADSFWCLSKLLDGIQDNYIFAQPGIQRQVASLKDLTKRIDAGLARHLEQEGVEFIQFSFRWMNCLLMREVSVKNTIRMWDTYLAEDRGFSDFHLYVCAAFLVKWSDQLVKMDFQEIMMFLQALPTQQWTEKDIELLLSEAFIWQSLFRDSSAHLRGSSAEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1S5</accession>
    <name>A0A6A6P1S5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="19">ETF-QO</shortName>
            <ecNumber evidence="19">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_343108</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 19">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="19">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ETF-QO/FixC family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="19"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1S5"/>
    <dbReference type="OrthoDB" id="437331at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000015">
        <property type="entry name" value="Electron transfer flavoprotein-ubiquinone oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049398">
        <property type="entry name" value="ETF-QO/FixC_UQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007859">
        <property type="entry name" value="ETF-QO/FixX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617:SF107">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21162">
        <property type="entry name" value="ETFQO_UQ-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05187">
        <property type="entry name" value="Fer4_ETF_QO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 19" id="KW-0408">Iron</keyword>
    <keyword evidence="14 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 19" id="KW-0813">Transport</keyword>
    <keyword evidence="15 19 21" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="620"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00052682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2457906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="660" mass="72647" checksum="3A048491D32DEF67" modified="2020-06-17" version="1">MRVPPTQLYFIASLAPSPPQIAMAARTLPASALRRNILSSSCPLRPFAASSSIVPIASTRTLATPRHAYQPALRIAGQRRTLSSSARTRLASAVESALDPSQLDREADEVDVCIVGGGPAGLAAAIRLKQLANEAGKEDFRVLLLEKAGELGDHIVSGNVMEPSAVDELLPDWRSEDNPSRFEHITPAREDRMRFLTKNRALWIPSPPQMHNAGNYIISLNQFVKWLGERAEEVGVEIYPGFAASEVLYTSDGSVKGVATNDLGISRSGQPKDTFERGMEFHAKVTLLGEGCHGSLTKQVVKKYDLRRDSQHQTYGLGIKEVWEIKPEKFQEGLVIHSMGYPLPSDTYGGGWMYHFGDNLASIGLVVGLDYPNPWLAPYGEFQKMKQHPLYRSVLEGGKCISYGARALNEGGYQSIPKCSFPGGALIGDSAGFLNVPKIKGTHTAMRSGMLAAEATYSAISSAGGGAQAGSIFLYDYEDKLRASSIWSELYQVRNMRPSFHGPLGLYGGIMYSGLEAYLFKGRVPWTLPHSKPDYAATKTADRCKKIEYPKPDGEISFDIMTSVSRTGTNHEEDQPVHLQVKDWDKHALKEWPKYKGVENRFCPAGVYEYVEDDSRELGVRFQINAQNCIHCKTCDIKVPDQDINWVTPQGGEGPKYVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2A5</accession>
    <name>A0A6A6P2A5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NUC185 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_343236</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1500.20:FF:000001">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000987">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="348"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="628"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="550"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="550"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="566"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2457954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1306" mass="147098" checksum="A090D62B1A18375F" modified="2020-06-17" version="1">MSPTLPQPRLRSRRAQAFLASSIQMEAEDLAKALERVKLGAENISSAKPGWIDSILTEPRPRKRTRRSKEQLKHGLEKEFLTPSTSFNTSWLNKLQQRWESPPIYTDLLTLAPTQTRTIIRFSREGLEGRVTGYKEITVPANSATAKNSTSLLRKPANRADFVRGGSGYFPFAPGGLDGVEAVAALEDEAIIRQENEKVKNTEGLNRIISFGVEGGLLEVPPGFKRGLDPNAKAIVEERTAEEVQKALEEESEPVPESARVDRLLNDEKPVASDDESEESDEIDDLLPVEYPALAPRGSLLQTSNRRSGREWAHMVDVNREITNFRELVPDMAREWPFELDTFQKEAVYHLENGDSVFVAAHTSAGKTVVAEYAIALAAKHMTKAIYTSPIKALSNQKFRDFRNTFDDVGILTGDVQIHAEASCLIMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDLERGVVWEEVIIMLPEHVTLILLSATVPNTREFASWVGRTKKKDIYVISTPKRPVPLEHYLWTNKQMFKIVNSEKQFLEAGWKAANDNLTGKDKATAKKSDEPARGGAQGGTTRGQQQRGGRGGAGQQRGGPHQRGGGPLAHRGRGNIARTGRGGGRTTAAQDRNIWVHLTQHLRKQDLLPTCIFVFSKKRCEENADALSNQDYCTAKEKSAVHMTIEKSIARLKPEDRVLPQIRRLKELLSRGIAVHHGGMLPIVKEVVEILFARTLVKVLFATETFAMGLNLPTRTVVFSGFRKHDGKGFRDLLPGEYTQMAGRAGRRGLDSVGTVIIVSPGAEEAPPAARLKQMMLGDPTKLRSQFRLTYNMILNLLRVEALKIEEMIKRSFSENATQALLPEHEKAVQLSEADLEKIKREPCDICDVDLEQCHQSCMKYERLTVELHSAVLASPAGRRMFAPKRMVVYKKEGIRTVGMILREGIMRGPDASLLVLEISTRKKRQPCDTLPYIARFAHLFAPLSSDLSDLSLRVGLVMLRDVECLTQMVFKVQTPQNIISDPNSQDAKKFAETQIAPLFRSWDFDEWDELDWSRIKDLSFRNILDERKKEADMAEQCQCIRCPKFLQHFTMEHDQWLIKKNIAQLRQMMSDQNLQLLPDYNQRIAVLKDLGFIDDKSRVELKGKVACEIHSADELVLTELILENVLADYEPEEIAALLSAFVFQEKTDVAPSLIPSLERGVATIIEISEKVNHLQTLHQVILSADDSNDFVSRPRFGMVEVVYEWARGMSFNRITDLTDVMEGTIVRVITRLDETCREVKNAARIIGDPTLYTKMQTCQELIKRDICATASLYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2M5</accession>
    <name>A0A6A6P2M5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_320384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2M5"/>
    <dbReference type="OrthoDB" id="10264848at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF97">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="249"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="802" mass="84307" checksum="B72E93F979A841E6" modified="2020-06-17" version="1">MSSAADADARPQPLHMSKSFSRFDPNPGPRPGSRGRASTVQGTAGPIPEIMYQSNAALVDDAGDGGAEKADIFAPRRNKDGGSSADHPAVGGENHPQLPESFDDLPIEIRSQTERFLESLSAKVHPSPLSIEALAEMFQDFYARAESHIATHIATLSARIGRDKSPSPSVASRTSTGSKTSGAGSGAKRTTSQDDVTGGEMLTASEIQGRRRARKLLELKKVALEEAVERAVCEKVYDRVWRHRSTDDEERDSKLRSRTAALSVVGIGLKELLVSADDVTEAARQSTVEKQDEVKEWLSGARENIHKMDDVKYPLGKLQHLTAAHKSIVETLSQLFPASSSADEILPTLIYTLITSAPEDINVISNLHFIQRFRASSKVDGEAAYCLVNLEAAISFLETVDLSSLRADEVPSDTSSSAPNKTTPSSPAKPVLSTSSTMPTTLSPPSKDALTATDPLLNPPPTPNSTGDAPRSPRRLSNLIASQTNRLEAASESVRASVLDSADQAIHSINSTVENSLAFVFGRLREQQQQQQHVLKDTPTSAAAGAAGTAANGTPNGPTTSVVVVPKTLEDARRLVSAPLRGTEAAAQQAVQHDDADASSVRSGVSEHSARGSSLSGLSARKVLFGGTEGSGEGAGGDAGAAAAAPAGDVSGAATAGTVPPAGAVESMRSFGNSLNPLKGFPGMGMLPRFGRGGEAASPPPPAAAAAADGVAAGENGTAAQEGRSQEQLPQVSPQQSKAEKERTAKGARATKAIEELRKTAPPVKRFVEMKDAKEVRVGEVEELLREYQRLAEALRRTIREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P330</accession>
    <name>A0A6A6P330_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_319481</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058846">
        <property type="entry name" value="PAS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF30">
        <property type="entry name" value="TWO-COMPONENT SYSTEM RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26131">
        <property type="entry name" value="PAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="867"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1214"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1168"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1375"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2458207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1401" mass="149628" checksum="14A88C2A17178DFF" modified="2020-06-17" version="1">MLSKARADDAPSIKTVTLARASLAAATAAAAATASKSPPAAAGLGAPSSLTPASAARLLVQVGVLEMVEADPRPAFVVDAGAAGSATATEGGSLNVIFANSALRSIPGLAFAVAGKPSGSASGSASPATASTSPLDGYAQFKEWVLGPSAVGGSPAPGAGPQRLQQRTFAFAGTVWSAVSLRGRIRVISGNSTSAAAEADATTPTFDGATGSVAAVLSDGVASPPPRLVEEAEVQDYFGNATVSDLETAAPLASVSEEVAPPVVSTIEPHDPPKDPPRSKPNSEVAFGADDEVLYPEAAILAPHFAPEHLDDAATVAAAALAAGIPKEIGFFDWTRLPASDDLPAHIQFARSVDWASTALGPIEYWSSDLRQMCNLIMASPHPAAMYWGEDLVAIYNEAYVLLAGQKHPRLMGQSYREAWSEIWDEVKGVFANAKTTGQATMKDDDCLFIFRQGFLEETYFSWSIIPMVGADGSVTGLYNPAFEKTRRKIAERRMLTLREVGERTANARDVKGFWQQALTALDSNELDTPFVLVYSVSEEADSEDSSSIHSASLLGSKQCFLEGALGVPTGHRAAPAQIDLKHGMEGFGPVFREVMKTDRPVLLDVGTGDLPVEMLEGIEWRGFGDACRAVVVCPIHPTTGEASLGFLVVGVNPRRPYDDDYGLFIQLLSRQLATSLASVVLFEEEIRRGQRAAKLAAQDRIMLSEQLAARTQEARDSETRFTRMAEFSPAGLFIADSQGHVIFCNDAWYEITRVSKDGASVDRWIDAVASEDQERVRRTWATLVEDVEPVTDEFRFKAPWEDRAGNRSETWVLFAAYPEKDDNGALKSVFGSITNISQQKWAEGWQKRKMEEAVELKRQQENFIDITSHEMRNPLSAILQCADEIATTLGEFRASGQRRIGDELLASSVDAAQTIGLCAQHQKRIVDDVLTLSKLDSAMLMVTPVDVQPLTVVQRALKMFENELATADIRMDFVLDDSFKELGIDWVRIDPSRVLQVLINLTTNAIKFTTSESRRTITVTLAASLENPSKDPGAVVRYFPSRAQPADMTRGPDWGPGEEIYLQFAVRDTGRGLTAEEKKLLFLRFSQASPRTHVQYGGSGLGLFISRELTELQGGEIGVASEAGKGSTFAFYIRARRSVAPRDQAEAPLPLPLAGLARATAAAATATATAAADKPDRERGAGGAGGGAPKVRDFAPPTGAESSAGADDGTPLSVLIVEDNLVNQKVLGKQLRNRGFGVRVANHGVEGLDALRASQFWFENAKAGAGGGGGAAAAAAAAAAEIHKIDVVLMDQEMPVMNGLACTRQIREWEQRGQVVGHVPIIAVTANARMEQIAALLAAGMDDVVSKPFRIPELVPKIQELAAKYPSAALCSRRGGEGLENGGEGQQQQLDWAPPPPSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3M9</accession>
    <name>A0A6A6P3M9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3M9"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="143" mass="15943" checksum="C892B0769A54974A" modified="2020-06-17" version="1">MVFVIPDPLAENNTSDRRYLLPASQNDANPPQTPREDQEETGEIQHFMITGNLDALLTVNGQGEFALSGFFHLVTEDFRHDAKPDLHSQESSDESEDGFSDQEDSQDAFSDEEGEEESEDSGESPAYDYDGYVVLDEEDADSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3U2</accession>
    <name>A0A6A6P3U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trehalase</fullName>
            <ecNumber evidence="6">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_283553</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="6"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3U2"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000026">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="7">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2458665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="740" mass="84842" checksum="5DB79889D436CEEF" modified="2020-06-17" version="1">MTSPSASTRLRTESAGDLDPLSAADIYYGKSHSLARKKERVRTYSGIVHTGDGRTIARAAMRRRSHDEQSMRPRRFLIRVEDTLKNLLSEEDTDNNMQITIEDEGPKTFSVGTESSNGFNRFDVRGTYMLSNLLQELTLAQDYGRKTIVLDEARLNENPVNRLTRLIRESFWNNLTRRIDGSNIAQVGRDPKDWTSDPRPRIYVPRGAPEQYEYYTRIAKEQPEVRLDVCWLKEPCDDPAYVRDLNEAPGMLALEMGEVTDPETGEKDLRGLPFVVPGGRFNELYGWDSYMESLGLLVHDRVDLVKSMVLNFCFCIRHYGKILNANRSYYLCRSQPPFLTDMAIRVYDRIKHEPGALDFLRTATLAAIKEYRHVWMSAPRYDPETGLSRYRPGGLGVPPETEASHFTHLLEPYAAKNNLSFSGFVQAYNAGTIKEPDLDEYFLHDRAVRESGHDTSYRLERVAANLATVDLNSLLYKYEADISRVIRTYFGDALSVPAEWCAPGMKPGQIERSATWDRATRLRRTRMDKYMWNRAKGMYFDYDTVRRVQRSYESATTFWPMWSGAASPERAAILVSRTLPRFEVFGGLVSGTEESRGAVGLDRPNRQWDYPFGWAPQQMLAWVGLQRYGYEADAERLAYKWLYMITKAFVDFNGVVVEKYDVTRPIDPHRVEAEYGNQGSDFKGVPREGFGWVNASYVYGLQLLRAHARRALGTCTTWDVFSKATEEDVFEGEDEIDSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P418</accession>
    <name>A0A6A6P418_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P418"/>
    <dbReference type="OrthoDB" id="3945206at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="486" mass="55988" checksum="58592243B01B0B8E" modified="2020-06-17" version="1">MASSEPTYQKISAHDILVFSDAELGRFLDEIRLPNGQAIVEVEEDLDQVTARLLRIPAENDALPQAPPQPSYHERLPTPPPPSDEEVEMQSYNELFNDGGNWMVFTIQLDNWEEFRKWQRYNRGDFGDLEEYSSPDFYLAYKGFIRAFKLGYGRLPEYTEAIERLLARHGFTRTFQLEVDPKRQDKLTTWIEYVGYMYWRHDAYVAKVERLQPLHDKAWNELVDSKVLLPYETEEFILSIERAVQDQSKWSAAWRALESVKSAALSTLRTTEKARNDPQHSTLTSEQRKWMIGKAHSKYDAARSSFELIKRRNDLVGDFIRRIKDYRIAKGNADRHRNLQRWILEQLPLIVAELNEGRSRSKMPRGRKRGLERDQDDVATEDQNSTQGANDQQSSLLDGIAYFTQIKARSKRSRRGDTVDEEPSSKRLKTDGLDPRRTTSGGTDATSTGRTEKSVIAANRPLRSKGTSLSLEISPKLRRSARIAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4B3</accession>
    <name>A0A6A6P4B3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_210619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4B3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12435" checksum="51B85F69D7591F84" modified="2020-06-17" version="1">MEPSSNSSRKAAAPGHFHLGILYHWYLFLPFSLAYAIDLSLSQYSHTHRCSCGPLQSNNPPKKENKRKGCNSTHKGKVRNKRGKNTDKKAPHLTTKDSLAELKSWSSRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4M0</accession>
    <name>A0A6A6P4M0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NBP35</name>
        <name evidence="10" type="ORF">BDY21DRAFT_384843</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4M0"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="91"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="343" mass="36016" checksum="B92913520DBC7429" modified="2020-06-17" version="1">MAPSLEEPAAQAFDSPQAALEAPLKAQPKLVAPEPEHCPGPSSSAAGTASSCAGCPNQSICASTPKGPDPDLPAIAARLSRVRHSLLVLSGKGGVGKSTFAALLAQGLAGADPRAQVGLMDTDLTGPSIPKMLGVEGEGVHVSGEGWEPVWAEFMLPSRDDAVIWRGAKKTGMIKSFLRDVSWGALDCLVVDTPPGTSDEHLAVNSLLRDAAPRGRLDGALLVSTPQEVALQDVRRMLDFCRKAAIPVLGIVENMSGFVCPKCKAESQIFRASTGGARALADEQRVPFLGAVPLDPRIGMACDYGESFLESYPDSAASKAIRGVVRRVTRAMALRYGEEIMHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4N9</accession>
    <name>A0A6A6P4N9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_211208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4N9"/>
    <dbReference type="OrthoDB" id="5409477at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="312" mass="34543" checksum="A79E60F4DB3E8A5E" modified="2020-06-17" version="1">MPSYLPPGTPPPPPLLAAAYPPSPYGGSRSASRSSAHTNSSAASPKHARAAGPAVMMYPDLQPSCAVCGAANMPGYPECPHESESLQKAVEMAEERVFRSRQLQEIRDWVVHKSREYVLRKYNQAVATRKAQQAEYLHRLPCYGLYVQYQGQPPLQPAALLQLKAQMADADARLRRAVDDDWRACCLQYPEVLDHFYSLVEWRVPNDRASSVVEPSLGSEGRERDRDRDRERKARRQRESRVPAAAMLDRDGAQTVPPERLARPPPGRRRDSGQQGRIKAPPVAPTPPVQHQAYGGAGGASPGNWNYFGGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P501</accession>
    <name>A0A6A6P501_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-activating enzyme E1 1</fullName>
            <ecNumber evidence="5">6.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_339432</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="5"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2458969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P501"/>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01491">
        <property type="entry name" value="Ube1_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01490">
        <property type="entry name" value="Ube1_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2660:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12550:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000015">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.60:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.180:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032420">
        <property type="entry name" value="E1_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032418">
        <property type="entry name" value="E1_FCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16191">
        <property type="entry name" value="E1_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16190">
        <property type="entry name" value="E1_FCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="14">
        <location>
            <begin position="903"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="780"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2458969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114845" checksum="B93CAB6F8754FC83" modified="2020-06-17" version="1">MTDVEMDSPPEAAMEQPLKPVSSSNGGIDESLYSRQLYVLGHEAMKRMSASNVLIAGLRGLGTEVAKNIALAGVKSLTLYDPNPAKIADLSSQFFLRPDDVGKPRAEVTTPRVSELNPYTPVSTHPSKKLVEDLDLLKEYQVIVLTESPLKEQLAIAEFCRANDIYLVVTQTFGLFGTIFCDLGKNFEIVDPNGENPVSGIVADIDSDGLVSAHDESRHGLEDGDAVIFSEVEGMEGLNDGKPREISVKGPYTFSIGDVSGLGEYRRGGIYTQVKKKKVMQFNSLQEELKNPTLMMSDFAKFDRPAQLHVGFQALHKFAENHGGAFPKPHGEADAAEVLKLAQAIAEESEEKVELDEKLINELSYQAQGDISSVAAFFGGLAAQEVLKAVSGKFTPIQQWLYLDSLESLPTSTKRSEETCQPIGSRYDGQIAVFGKPFQDKLFGIKIFLVGAGAIGCEMLKNWAMMGVGAGQGGKITVTDMDQIERSNLNRQFLFRPTDVGKLKSECAAAAVTAMNPHLTDKIVTLKDRVGPDTEHIFNEDFWHQLDVVVNALDNVEARTYVDRRCVFFKKPLLDSGTLGTKGNTQVVLPKLTESYSSSQDPPEQSFPMCTLRSFPNRIEHTIAWAKDLFHTYFVGPPELVNQYLTIPNYLSSALKQTGNEKQTLETLQEFLVTEKPLGFKDCIVWARRQFERQFNNNIVQLLYNFPKDSTTSSGQPFWSGPKRAPDPLVFDPENPTHFAFVEAAANLHAFNFKISSKGVTRQDYISTFQEMIVPDFKPDPGVKIQANDNEEDPNANNAANNDANELQSIADSLPAPKSLAGFKLEPVEFEKDDDTNYHIDFITAASNLRAENYKIAMADRHKTKFIAGKIIPAIATTTALVTGLVNLELYKVLDGKDDIEQYKNGFVNLALPFFGFSEPIASPKGTYQGPKGEITIDKIWDRFETENVTLQEFLDDFEQNRGLSISMLSSGVSLLYAAFYPEAKLKDRRPLRLDKLIETISRKPIPGHQKNVILEITAEDTTGEDVEVPYVMLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P587</accession>
    <name>A0A6A6P587_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P587"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="96" mass="11025" checksum="E5E872276C59B979" modified="2020-06-17" version="1">MISGTRIWFTYASWWRVMMNTQKKALKSTGTTTKLQKQTTRQPVPSPSNPLKQTMRLPPLPINLPKQQIRPPTPLIHLPKRTRLPPLSTSLAKRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5J9</accession>
    <name>A0A6A6P5J9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_409966</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5J9"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="98"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="345"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="714"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="744" mass="82516" checksum="E6B07EBB907189E8" modified="2020-06-17" version="1">MARSNLDPAEILEDNIGRLIDNPLLKYSNTEADRKAVEFAIEYGFGHMRELFVKASRILRDPPAWRGVPDLTCEEYNAQRREESRPGFWQQPKALRVTIITLCIAAVIQGWNQTGSNGANLNWPEEFGLHVDPSDPRSTTSDIAIFALVNSITYFAASLIGCWFSDSLNEYFYGRRAAICISGVFIFASVIGGACTHSWGALLATRILLGIGMGSKASVVPVYAAEVAPVHIRGSLVMNWQLFDAFGIFCGFTANLAVSQIGPLAWRFQTASSFLPALILLALIFVCPESPRYLMKRGRSSYVDAFDALVALRGSPILAAKELYYVHSQIGVEQTLLSHYRRGVSDTDSEAGSRSRRVGYSTATSEKRSQKEQSPAQGAAEPSRRSFVSGIALQLGLVQLGQPDIYEEHPNCVDSDCHPEWREKTWKDRLEALKPPPDRPINYWQKLGQLFTERRIRRATVSAVVVMISQQLCGVNIVAFYSSTLFRDANADRMGALWLSWGIGLANFLFAFPAYWLIDPKGRRFLLLITTPALGLTMLAAGLSFLIDEENPAHVPVISLFFFIFFAFYSWGMGPVPFTLSAEVFPLENRVVGMSFAVFVNLFGAGVLALIVPLLTSALGHILIFCIFAILNAVAFFLIFFFVRETAGAVLGGTPEEGSINYVSLEELNYIFGVSTKMHSAFQIEKFKSYFTGDVSKRRTQLYVWALDRRRTQEEQHAEAEGQGETTEDGMSSDGLGITGYQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6C2</accession>
    <name>A0A6A6P6C2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_362112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6C2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2459357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="323" mass="35673" checksum="8FBAB3518E288E7E" modified="2020-06-17" version="1">MHCVGSCVARSQEKKGDAGREPRRQPRPPRPWRAALGCGVRNIWTNSWVQTAERREPTLPNQPYCKGGLCFNVIRDLMTHINGKKHQRAGLGDGPRIPQPRGPGQKAWVDKYLVPFLRTHGYFRGAPISSLDEPSTSNCHNSDVEMESDVETQYTRNDPASPDLEEVGDEFVDMTLGANANLHGDPATDLPDLAGPPGSVLATEPPATALDLAPDFDLLGFIIAENIGHGNSAHDDPPLQNQSVDNQEIWDFLDSHAALRSPLYHTHLVSSGSFEHRCEDFLAVENHLGFGDFLPKMEDADYEKLSLYAQALTIEMDVDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6D9</accession>
    <name>A0A6A6P6D9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T-complex protein 1 subunit zeta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">CCT-zeta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_338556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6D9"/>
    <dbReference type="OrthoDB" id="10052040at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2459551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="538" mass="58731" checksum="0CFFF0B990C1CC6D" modified="2020-06-17" version="1">MSAAQLLNPKAESRRRGEALRVNISAGEGLQQVLASNLGPLGTLKMLVDGSGQIKLTKDGSVLLREMQIQNPTAVMIARAATAQDDICGDGTTSVVLMVGELLKQADRYISEGLHPRVITDGYEIAKNEALKFLDEFKMQREVDRELLLSVARTSLSTKLNSTLAEQLTPAIADAVLAIYQPPAKPDLHMVEIMTMQHRTAADTQLIKGLALDHGARHPDMPKRVENAYILTLNVSLEYEKSEINSGFFYSSAEQREKLVESERRFVDEKLRKIVELKKQVCGNDPKKNFVIINQKGIDPMSLDVLVKNGILALRRAKRRNMERLQLVCGGTAQNSVDDLTPDVLGWAGLVYEHQLGEEKYTFIEEVKDPKSVTLLIKGPNAHTITQVKDAVRDGLRSVYNMIVDGCVVPGGGAFQVACAAHLSSESFRRQVKGKPWNGVAAFADALLVIPKTLAANSGHDIQDALATLQDEQAEGNVVGLNLITGEPMDPVQEGVYDSFRVLRNSIASSSGIASNLLLCDEMLKARQMGKGDQPGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6U2</accession>
    <name>A0A6A6P6U2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_369679</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="14"/>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6U2"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23285">
        <property type="entry name" value="beta-trefoil_MIR_PMT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000044">
        <property type="entry name" value="Dolichyl-phosphate-mannose-protein mannosyltransferase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="642"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="736"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="336"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="405"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2459716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="787" mass="89203" checksum="A6D2815C6E4F58C3" modified="2020-06-17" version="1">MSSPAPSSVRHRGGNASSKKRGTTPNPETRDVDMDVLNKAHADAQAAQPSSEWDYKVALGIITMMSFVTRFWGINHPSQVVFDEVHFGKFASYYLQRTYFFDVHPPFGKLLFALAGWLVGYNGEFLFENIGDSYITNKVPYVAYRAMPATMGALTVPTVFLIMWESGYSLPACVTAAGLMLFDNAHIGQTRLILLDATLVFFMALSVLCYIRFYKLRHAPFGRKWWKWLLLTGVCLSCVISTKYVGAFTFFSIGVPVVIDLWDLLNVNRRQGALSLPEFGKHFAARMTGLLVVPFLIYLFWFQVHFTILSRSGPGDDFMTPEFQETLSDNVMTSQSIPIDFYDVLTFKHKETKVYLHSHPDRYPLRYEDGRISSQGQQVTGYPHNDTNNHWQIMPGKPLPEGVETRRVKHGDIVRLRHVVTDTILLTHDVASPYYPTNQEFTTVNHADGDGQRYNDTLFEVRIENAKSGQEFRTKASHFKLIHYPSKVAMWTHTTPLPDWAYRQAEINGNKNAVQSSNVWLAEEIPSLPPDSDRLKKEERVIKHVPFLKKYFELQRAMFYHNNALTSSHPYASFPISWPFLLRGVSFWTNNDTKQQIYFLGNPVGWWLASSVLAIFAGIIGADQLALRRGVDALDERTRSRLYNSTGFFFLTWAAHYFPFFIMGRQLFLHHYLPAHLASTLVTGALVEFIFNIEPQDDELDAAPAPPAAGAGKKGGAAQQAPQRRKPVRERLGSQSLVAAWAATGVIWAVVVWSYLFFAPLTYGQPGLSVQGVNARKWLAYDLHFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6V3</accession>
    <name>A0A6A6P6V3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_338713</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000481">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000585">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="777"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="719"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1091"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1121"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="445"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="603"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="719"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1133"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2459609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1454" mass="161883" checksum="8DCB021EDBAC59B9" modified="2020-06-17" version="1">MSTASPTRPSRRAAAASRRKLVISDDEDDSTPSRSLADTVANDDNDEEEFTPAPQKSPTRRRRTAAADAVTPHRAGGRTRRAPQPAGESVMEPSQVFSPPPDTVDASAMRPESPTKKKAAASPRKGGRKTSARGAASARQSRAAVHVSKDAPDLSQLPTPQASQSPEPASQARAPSQQLSERGSPLADITDAAVNEQSLAPADKLVTNVDPRAAVLEKPIDIVVRTRNNAMPASLSQEPGPPKSRIVITYLTLTNFKSYAGKQEVGPFHASFSSVVGPNGSGKSNVIDSLLFVFGFRASKMRQGKISALIHNSAAFPDLEYCEVEVKFQEVKDLPTGGHEIIPNSCLSISRRAFKNNQSKYYINGRESNFTEVTTLLRGRGVDLDHKRFLILQGEVESIAQMKPKAANEHDDGLLEYLEDIIGTSKYKTPIEEAAAETETLNDVCLEKSNRVQHVEKERNSLEEKKNKALAYIRDENELAMKQSALYQVYVEECNDNLQVMQEAMMQVQAALDEEVRKHEGNEEGIKALEKQYKADAKEYERMEKATQAMLKELAKKDKESVKIEEKKKFLAGKQKKLEKQLENSKFAVAESQTLGRQCADDIEHNAAQIAQLEEEMKVEEKELANIRDSMKGKTQGISDQIAVKQKSLEPWNAKINQKHSAIAVAQSELDILKEKDNAGANATAQVQAKIEEFNETREAKRAELEECKQHRKELEAEAKRVEESMEELAQKEPSLKSKLSGARQKADEARASLSATQTQGNVLTGLMRLKESGRINGFHGRLGNLGAIDQKYDVAISTACPSLDNLVVDTVEVGQQCIDYLRKNSLGRANFILLDRLPRRDLSPIQTPENVPRLFDLVKPKHDRFLPAFFSVLQNTLVANDLAQANRIAYGAKRWRVVTLDGQLIDKSGTMTGGGTRVARGAMSAKLQAADVTKDQVARLEVDREALEKAFAELQEEQRSLDAQMRSLVREQIPQAETAAQKLVLELDSVERNITDAEKRIRELQAEKQPSKADRASMVKLEKNIAAMEEEVNALRAEMAGVEEEIKALQDKIMEIGGVRLRSQKAKVDGLRDRIETLTEAMSTAEVGKAKAEKQRVKHEKAQMQAEEELESLAAEMEKVDQEINSQTKDASGSKRQAEEAQDALETKKDELQALKAELDTKTAELNETRGVEIEIRNKLEENQKVLTENQRRLRHWQDKLSKLGLQNVSDLGEEQGQETLPTYSRDELEGMDKSALKDEIEELEAKTQNANVELGVLSEYRRRVEEHATRSSDLVEAVTRRDTAKKRCDDLRRLRLEGFMEGFSAISLRLKEMYQMITMGGNAELELVDSLDPFAEGILFSVMPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFRNVSIVASYIKERTKNAQFIVISLRNNMFELASRLVGVYKVNHMTKSVTVENRDYITQGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P781</accession>
    <name>A0A6A6P781_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_317212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001675">
        <property type="protein sequence ID" value="KAF2459283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P781"/>
    <dbReference type="OrthoDB" id="1898734at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF2">
        <property type="entry name" value="PROLYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="68"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="457" mass="51934" checksum="BA576808E7CF56D1" modified="2020-06-17" version="1">MDTPSCAKILEQRSHIVPGKIRITEYVFEAPRDHSKPEAGRIRLFGRGATKTEKPAAPEADPKPKQPPWLVYLQGGPGFECRSPHYYPFVHMMLDRGYEVLCLDQRGTGRSGAVAASTLGLRGDDPVQARYLASFRADSIVRDCELVRALLTADYPPEKKKWTVLGQSFGGFVITSYLSMYPDGLREAFVLGGLPPISVDAPDEVYRRLYRKVIEKNDIYYNKYPEDVDRVKRVVGLLRRFGDSTVRLPSEASLSARRFQQLGIMLGFHGGVDSLHDIVSRASSDLDQFGHLTRPTLSAIESSLPYDDHLIYSMLHEPIYCQGAASNWSAHRVRQDYPEFALDTQGPVYFTGEMIYPWMFDDYAELRKVKGPAQMLAEHSDWPALYDKAQLARNEVPVYAAVYVDDMYVDYDFSLETARSIKGCKIFITNMMYHDALRSRTEEVLRSLMFLRDDCMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7F0</accession>
    <name>A0A6A6P7F0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Chromatin modification-related protein EAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_179912</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EAF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7F0"/>
    <dbReference type="OrthoDB" id="440324at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="74"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="122"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="188" mass="19747" checksum="BAB69C66E60BA800" modified="2020-06-17" version="1">MAENAPPANAAANAGPEGARGMPYYEKLRKDLRGILQRKRDLDNELTKLEETIHQAESTYLEETTAGNIIKGFDNYIKGSAGGAGAGGSGAGTSSRRKAAIGDQDRLFSKSSAGPQNDSPLPTSAQTTPSHAPTPTSSFPSARESNHPTPTSTTTSKGASKKKKVADKDDEEADGKPAKRGKITYGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7F8</accession>
    <name>A0A6A6P7F8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flavin-containing amine oxidoreductase-domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_281492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7F8"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001716">
        <property type="term" value="F:L-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF382">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025507843" evidence="2">
        <location>
            <begin position="24"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="3">
        <location>
            <begin position="187"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2459809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="691" mass="77377" checksum="3854C17469AEEC16" modified="2020-06-17" version="1">MLALRSALSSSLAFWSLFVPSLGNAVSSDSVSFIRPAAVESGGAQNIEIEYHRPIDGELSIHYGACDLDDPAFSHHRIGTAYIGNHELAKRHVGWDENRPSRFVWVAPESLLEHGCLHAFSGIELVGRSDPIPVMKRNNQRRAVFAEIADSEGPWFDGVEYLSEKEPDDVFVAQAKSSTVGIIGGGMSGLMTAYLLDSVGIHDYTIIESSYRIGGRVHTTYLNGTSPDDYQYQEMGPMRFPVSITDPDTNETIQIMDHRMVFQLAETLNEMNGNDPDYAVNFIPWIQNSPNTPTSTSKRRPDGTVPGTAEVEESPAYQDNPNATYSNATAVAEAEEAYEEWVGLDEDDVRAIAANIFQAHKDAVDRGLLDFSEAEYLRRVLRLDLNITDQVDTIDDHFPSWEYDSVYFAATEWRTIDKGLSQLPAAFGPLVLNRTMFGTNVHEMEWDEESEQMTIKWRSDNPFDMNTDSKTFDYTVVAVPFSKVRIWRLPDYTSLLSRAINTLNYQQACKVALHYKTRFWEHLEHPIFGGCGSTDIPGIGSICYPSYKLNSSLPGALLANYRSGVLARSLGALDEVEHVALVQRAMAEIHGEIANEQFTGAYDRICWEFDRHQAGAWCSPLSGQQELYLPAYFHTEKHTVFVGEHTSYTHAWIFSALESGVRGTTQLLLEMGLVDEAKAVVDQWMARWISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P7U0</accession>
    <name>A0A6A6P7U0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative ATP-binding cassette transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_336962</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P7U0"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001305">
        <property type="entry name" value="ABCG transporter ABC superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="505"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="50"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2459939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="655" mass="72849" checksum="150C51E859114494" modified="2020-06-17" version="1">MSASSSTDGTAHEHERPQAERRFGDPNRDPELNPVKSVHLVNDVVHSFAWKDLNVVVKDRNTGQPLSILSDANGIVHAGEMIAIMGPSGSGKTTLLNSIAHRAAAAGATTTGTMLANGQPTTWEKIRDLSSYVEQEDALIGSLTVRETVYFAAKLALSSHMSRKELHQRVDDLIASFGLGAQKHTIVGTPIKKGLSGGQKKRLGVASRLVTDPKILFLDEPTSGLDSTLSYEVIKYIKEIGRKNNLVIIASIHQPSTSTYHMFDKLCLLSLGKTCYFGPISEARAYFTKIGYEMPAEVNPAEYFLDLINIDLVREGDDVRARMDHITREWAASNESVLVKNEIDRTIEAAKHPEKTMPDLDKIKINKPNPVVIPWTLLHRSWIKSYRDVVAYGIRIVMYLGLAILMGTVFLRLKSSQTYIQPFINAIFFGGAFMSFMAVAYVPAFLEDRATFAKERANGLVGPLSFMISNFIIGLPFLFLITVLFSIVIYWLTNFRNDGSAFMMWVLWLFLDLVAAESLVVLVSCVFPVFVVALAITAFANGLWMCVDGFLVPMNILNAFWKYVFHYIDFQAYVFQGMMVNEFKERTYDCTTTPDGGYQCMYPSELNSEGKIAGTAVLDAFGINTGLQGTWVGIMIGIIAVYRILAYLALRFVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P823</accession>
    <name>A0A6A6P823_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7896 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_361889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2460024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P823"/>
    <dbReference type="OrthoDB" id="5377599at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057218">
        <property type="entry name" value="DUF7896"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42031:SF1">
        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25438">
        <property type="entry name" value="DUF7896"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7896" evidence="2">
        <location>
            <begin position="298"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="564" mass="60777" checksum="EC769C7FAC0C1575" modified="2020-06-17" version="1">MNRNCSIQSAPAGISMSRSHSGASSMNSMASLSRAYSNDVPGQPTAFGNYRPSQTVQRTRSHQQTLPEVSEVPELSQQEQYHQEIACETYDPADYVTKLSGNQQLLPEFPETGNFDPSRQPLNVWTDFAALPATPSTSGGLTAGSTAASDMSRDWSWTSGKGVTEALEIMRMNSSFSTSSNNNEHNLNEDSFNQSVADPHCASSTTNEAFNFLVKQLQIAPKQSDASLSAEATQLAGHPIRQTTSSDGTTKTQVPIQALAHSRPQREKTVCERCPEPVEFRGEHELRRHTERVHATKRKVWVTIDAQKAGTATGSPDNPVPAMPLAKCKQCLAEKKYGAYYNAAAHLRRAHFNPRKRGRKAKGDEKRGGKAGGDWPPMEVLKGRWMKEVEEEVPSNVGAGAGNGAVPTPTREGDYSSSAEDALDDMDLGNDNDDAAFDSDEQQFLLQQVVSPTASSTNDSPADLPGGSFVVTPESNSTIAPPMAPFEAGFVDMAQMNDWSAWMAGSGDYAVAAGGAPQQQHDFGNEYFNFDSGACTQLAPPFDVQQTTTFGGVGLDESSLFATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8E8</accession>
    <name>A0A6A6P8E8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactonase, 7-bladed beta-propeller-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_334931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8E8"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025630756" evidence="2">
        <location>
            <begin position="18"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="397" mass="42750" checksum="632E68EE19BCB257" modified="2020-06-17" version="1">MLSVAFLTLASAAVSVATNLYVSSYEGVVHTVKLKQGAGDLLYLEPNATTAGCASSPSWLELDGENRILYCIDEGLQFPQPAGSLSSYNIQENGILAQQNRFQTVVAGPVHGVLYKKGDQQAMAMAHYSGSSITNWKVSLEGDITFLTNVTFTMDSPGPNEQRQEAPHEHQALIDPTGNFLLFPDLGADLVRVFSVDEHLNMQREEPLAVEPGSGPRHAAFWQADDESPLYLFVVTELANTLTSYAVTYPEEGGMAFEEKFVTNTFGGETIPEGAAAAEIQVAPSNDFILISNRNDSSFMLPNIDPTNSTLEESDSIASFRPSAADGSLEFVQLTPAGGLFPRHFSLNAAGDVVAIALQRSSRVVLMARDVHSGEVGNPVGVVELEGELTAVIWDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8S1</accession>
    <name>A0A6A6P8S1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_383939</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8S1"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="244"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="469"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="658"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="628"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="695"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1042"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="629"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1042"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1070"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1100"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1175"/>
            <end position="1192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2460217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1251" mass="140560" checksum="0DD7A3F6F5FA407E" modified="2020-06-17" version="1">MAEEQQQQYKPGGHYSGRNPVPTVRKFVESLDRDKKERDRKIDEAERDRKQQEGLSGQVREHVPKPTVSRNQKRVTDPTTGREVVIEDVNKDMIREVENPTLSVPNANLNKDTPIKTDPTQSGKEYKENQDVTAPPDPVAEGTTSDVPIHGEKTNVLFHPTPSVSYEPMFNVLEKRAMGLCAGIFVGIILVGKMFNGSLKGLMPLSSVVASGVWLWMKEVIRSGREMEWHSEQTRGQMATANLLPESVEWMNTFLGIVWGLINPDMFQSVADTLEDVMQASVPGIIENVRVAEINQGSNPIRILSLRALPDGHMKEIKDQIHEENKKTKDPQEAAADEEGGDFYNLECSFAYHAQPSGKRAAEKARNMHMQLVFYLGLKGLFGVPLPIFVELQSLVGTVRLRLQMTPEPPFLKNLTFTLMGVPHVQAGCVPMLEKGVNILNLPLISNFVNYAIGAAASMYVAPKSMSIDMRAMLQGDDITKDVMALGVLWIRIHRAVGLSKQDRRGSEHGGSDPYITLTFSKYGKPMYCTRVITDDLNPIWEETAALLVTPEYIKAAENLSVELWDSDRHSADDIVGKVELSMQKMIQHPGKMYPQVSRLAGMDADSSMPGELHWEVGYFGKPAFRPALRSDGRNKNLPRELQDKPELQDEKGVQHNQMENAVQNTPPDPLWPSGVCHIVVHQIVNLELENVKGSEGKRKGREYEPAKPYGENTEEEGRNLPTSYCTILFNDELVYRTRSKAVSSQPIFNAGTERFVRDWRSAIITVTVRDQRNREHDPILGVVPLKLSDILETSSQVTRWYPLDGGIGFGRIRISLLFRSVETRLPANMLGWDVGTFEFMSDRILATGYTQHARLKMRTGGSIGRVPRSIGSNLPEGDGYFWDLTKAHQKPKEEHELRLPVKYRYRSPVVFEFHVPGRRKADAYAIVWLQHLIDNEDTPINVPIWQTARPARLTQNYITEENCKKEVGLEDLKEVGRLQFRGRFKAGMDESHERFVIDSDSRETYETWEACVAEGVRQRVVEKELPERVAALHAESLTEGRDVLRDAPEEEKEKWLSRDGTDWSGAFGHDPRAYMDARGRKRREPGTDPPLHDPHHPSEDEEREAEDEDERDSSSEDLGIQDAENTGSAADMDGQRQQAQHRRAQQEQGKSVDGAAGEDDMPSNEVRASVDTQATNGTATSTSNASASAGNVNRQNRRTEERKQRGLMQWTPARNAKFAKDQGIIGMRKVKGKITGGLEGRKPGVETETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8W4</accession>
    <name>A0A6A6P8W4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Clathrin adaptor complex small chain-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_315411</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8W4"/>
    <dbReference type="OrthoDB" id="10261046at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="105"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2460257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="240" mass="24436" checksum="A76FB9602FE66662" modified="2020-06-17" version="1">MINAVLVFNNSGQPRLTKFYTQLETSVQQRLISEIFTLVSNRPPSACNFLPLPPLLQAQSTPSATTTRAGGTVSPGSGAASSSTTSTTTTPAATTTTPSDTPSLVTYRHYATLYFILISTATESPLALLDLIQVFVEALDRLFENVCELDLIFNFETLHAALAELVVAGVVVETRLDRVVAGVRAQGAVAKRPVNEGKAGGGGGGAGGAGVGGGGGAGVGGLGLGGLGAFGRGEGIWTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P8Y3</accession>
    <name>A0A6A6P8Y3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_162049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P8Y3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="82" mass="8927" checksum="E3DC2E2181C74F3D" modified="2020-06-17" version="1">MTGYSGLLMASWFLSLYLGVGFSLPFFFNNAFCANGSVLAMVEGCSLVISFLPIFPVLNSAYLLFSWVLCRGLKRVSASVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P920</accession>
    <name>A0A6A6P920_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">agmatinase</fullName>
            <ecNumber evidence="4">3.5.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_335029</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>agmatine + H2O = urea + putrescine</text>
            <dbReference type="Rhea" id="RHEA:13929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="3.5.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="4"/>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P920"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000006">
        <property type="entry name" value="Agmatinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF30">
        <property type="entry name" value="AGMATINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025616068" description="agmatinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00050304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00066392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="400" mass="43176" checksum="A5F8DE353944C2B0" modified="2020-06-17" version="1">MAMKVLATVAGALAALVAAHGHHDQETFEGPHKQLWYNTLPGDGGTQADSVFSGIATFGRIQYFPCLASHDAKYDIAFIGAPFDTGTSYRPGARFGPSGIRQGSRKVGFSGGYNVPLDANPFNSWATVLDCGDIPVTSYDNAYAIQQIEEGHNSILSRAPATDAKKKGPSKKGKTLPRVITLGGDHTITLPLLRSVNREYGPVSVIHFDSHLDTWRPKVFGGAPSEQASINHGTYFYHASQEGLLANDSNIHAGIRTTLSGLSDYENDGYCGFEIVEAREIDTIGMHGIIRKIRERVGTEKPVYLSIDIDTLDPAFAPATGTPETGGWSTRELRTIIRGLEGVNLVAADIVEVAPAYDTNAEHTTMAAADTLYEVMTLMVKKGPLSQTIEQEGHENDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P944</accession>
    <name>A0A6A6P944_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIP18 family-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_369879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001674">
        <property type="protein sequence ID" value="KAF2459973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P944"/>
    <dbReference type="OrthoDB" id="2746at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000007">
        <property type="entry name" value="Cytoplasmic protein required for cell viability"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIP18 family-like" evidence="4">
        <location>
            <begin position="73"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2459973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="199" mass="21542" checksum="3B3E3E8DF1E1CA77" modified="2020-06-17" version="1">MEPDNKQNANPTIINPSDLPSRRRASAVKRHGDGAAGLFDGLVPPYAYFNDPFDRSSRESSLDEDDVVEEIDEQEIYDLISTISDPEHPLSLGSLAVVNLPDIHIKPPASPRSSISTVVVEITPTITHCSLATVIGLGVRVRLEQALPPRFRVDVRIKEGTHSTGDAVNKQLGDKERVAAALENGTLVGVLRKMLSTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9I0</accession>
    <name>A0A6A6P9I0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_168185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9I0"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF7">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="64"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="320" mass="36557" checksum="21C29E880AA1983E" modified="2020-06-17" version="1">MATEEPPYSPASEDTAMDDDLDLSIESSDSAEPSSEGGFTEQRDEPASSSLSPPGHFYKPFPLMSLPTELRLNIYRMALCRHKPLLLHVERKEDPLRDEALDEDSSSGSTTSEGDRSESSSQRRRRRRRHRRQRSRVTMRLPPRTELKEGLNTEPIVPNLLLASKTVLREARPTLYSDNTFVLKLDSALYSLSSLHQRSRSLIKHVRLTVPTHHDILEGFAELVRLGLRYCWGLRTFTIVLPYMFPDDGGISGSTNVYANAFHILRWLPQTCTVRLEGHAHKDIKKVVEENTKLAVELDEQAYQRRQHQMSDLQSQPPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9J8</accession>
    <name>A0A6A6P9J8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ANTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_335764</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLA2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9J8"/>
    <dbReference type="OrthoDB" id="10262320at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17007">
        <property type="entry name" value="ANTH_N_Sla2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1410.10:FF:000004">
        <property type="entry name" value="Cytoskeleton assembly control protein Sla2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000021">
        <property type="entry name" value="Cytoskeleton assembly control protein Sla2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035964">
        <property type="entry name" value="I/LWEQ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002558">
        <property type="entry name" value="ILWEQ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030224">
        <property type="entry name" value="Sla2_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407:SF15">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01608">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00307">
        <property type="entry name" value="ILWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109885">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50945">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="7">
        <location>
            <begin position="11"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="I/LWEQ" evidence="8">
        <location>
            <begin position="811"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1013"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2460556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1054" mass="120314" checksum="E8A6788BB060840D" modified="2020-06-17" version="1">MALYGTTRNVDMGKQESELAINIRKATSIDETAPKRKHVRSCIVYTWDHKSSQSFWAGMKVQPILADEVQTFKALITIHKVLQEGHPIALKEAQSNTNWIESLSRGIPGGEGLRGYGPLIQEYIFYLLAKLSFHRQHPEFNGTFEYEEYISLKSINDPNEGYETISDLMSLQDQIDTFQKLIFSHFRSGANNECRISALVPLVQESYGIYKFITSMLRAMHTTLGDDEALSPLRGRYDAQHYRLVKFYYECSNLRYLTSLITVPKLPQDPPNLLAEDEERPALPARPRNETEPHPTPPRAPSVDPEPINEFWKNEQKRQQDEYAEEQRRLQEQWEASQRQQQAAALQAQREFEEQQRLQAEQQRMAQEALLREQYRQQTEGRLAELERENLNARAQYERDQLMLEQYDRRMKALESELQQLNANFQQQTTSKDEQIKALQEQLNIWRSKYEALAKLYSQLRHEHLELLQKFKSVQLKAASAQEAIEKREKLERELKTKNLELADMIRERDRALHDKDRVTGGHREELEKLKRELRFALEKADNAERAKGSELSAMLSRHNREIDDLQEALRNKTRELDGAHMKYRESDSTLERQLREKEEELEIFKAGMDQTLLELNELRQSHQETDHAMDGQIDTVILDNVRKINDIIDSVLQSGVQRVDEALYELDSSMQAGNQNASGPYVLSQIEKASTCAMEFSTAFNNFIADGPNSTHAEIIRTVNAFAGSIADVLSNTKGLTRFASDEKKSDQLVNAGRQAAMSTINFFRGLQSFRLDGLEDIQKTDVVINNNNEVQMNLQKLSKLADAFGPRSKITNAQGDIGDLVDRELTNAANAIEAATERLNKLRSKPRDQYSTYELKIHDSILEAAMAVTNAIAQLIKAATASQQEIVREGRGTSSRTAFYKKHNRWTEGLISAAKAVASSTNLLIETADGVISGRKTHEQLIVASNDVAASTAQLVAASRVKASFMSKTQERLESASKAVTAACRALVRQVQDIIAQKNKDDNEAVDYTKLSSHEFKVQEMEQQVEILQLENKLAQARTRLGEMRKISYQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9K5</accession>
    <name>A0A6A6P9K5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_406415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9K5"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF17">
        <property type="entry name" value="STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="315" mass="33217" checksum="CB56C496C1CF349D" modified="2020-06-17" version="1">MPLLSAILGIKTPLLRTLVPCVGLAYAIQAGSALPSIAFRTERFFDTSAFLTYLSCTGLSLYLPAALDARAAGAAAPSLLGALAAPSSLNWRRAAVSAAAAAWSVRLGGYLLARITADGGRDARFDDIRGRPGKFAGAFAAQGTWVAVTLLPVLAVNAVPAGAAPAGLLLTDVAGAAMWAVGFGVEALADGQKSRWKRDKEEKRHAEEFITSGLWGRSRHPNYFGEILLWTGVATWAGGLVVRDTVLKGLGLSLGLGSRLSMLGLVFASPALVTLLLTKATGIPIIENKYDKKYGHRADYQAWKENTPVLVPKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P9T4</accession>
    <name>A0A6A6P9T4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gag1-like clamp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_384141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001673">
        <property type="protein sequence ID" value="KAF2460562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P9T4"/>
    <dbReference type="OrthoDB" id="5422958at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053274">
        <property type="entry name" value="Fluconazole_resistance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065:SF1">
        <property type="entry name" value="DUF4050 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065">
        <property type="entry name" value="FREQUENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gag1-like clamp" evidence="2">
        <location>
            <begin position="67"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2460562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="283" mass="31173" checksum="9534251E96881FDE" modified="2020-06-17" version="1">MATDTPSSTREVRRAAQRMLNERVRNDFEWDPETPEPGPLEGAVEYRERYYGTTSGPDSEPDVAEEPYKFESPDSIGNAMERRRKRRKRRRRKALEEEMTWNEGMECFVRRRDAWTSATRSPDPATPFLPNSSEETTTSDAHQNGSLGYSTPLVPLAPPILPPDNPIRAGISPRTYTDIYSKVVLSSRTPTVPINLADMTGALVHGWKEAGEWPPKPNPPDPLIGRRKRASGSHGGRTDGILANHPHVKKGVESMKRVLRLSGSSHGSGHGASGGTLAGENGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PA91</accession>
    <name>A0A6A6PA91_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_279573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PA91"/>
    <dbReference type="OrthoDB" id="5150140at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2460789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="190" mass="21447" checksum="D7E83FD58403C24B" modified="2020-06-17" version="1">MALKLYIHPCIHKPPHHLHPPQADKPLRIRIQGPLESIQKLLPNVSWDKIVSFPQPGGLELASITHQALYGWKALRMANGALMVWDEYLAWVMEGRRALDHIDYYGVTFDHLVPADDPDPEVFAINIIEVDNDGGKYANEVLSFSVNPTDYTGSKVLAVPRCCQRKKGTQDRRLINGLVAERDSEVQRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAH9</accession>
    <name>A0A6A6PAH9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAH9"/>
    <dbReference type="OrthoDB" id="19174at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="249" mass="26171" checksum="E5EC1777E263769A" modified="2020-06-17" version="1">MASNNTVLTIDTLLNLVPDRPAAILSYLSSHPTLASRQDSHGYSLIHAAASYAQLDLLRALVRTYNAPVDLRDEDDETPLFAAEAVDVARVLIEELGADPGARNAEGQTARQKMEDEGETADVAAYLRGNEGAVVAADAALDQSGSSLEDATAASAGAPENADVHPPPPLPANVSISVGTMEPLPDEGPDAPDPAFRARIEELAARDDFATEEGQRRLRELVTEAVVGLEAEAGRGDAGGRDATRRRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAJ7</accession>
    <name>A0A6A6PAJ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_376771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAJ7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2460970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="369" mass="39815" checksum="D0895CE0081F8C22" modified="2020-06-17" version="1">MAVISKIINPFNFFGGGKKAAEEEKEPEIEAVSRTFQVGHPDDKLQVETVSQPSPDFASTWTEHSWPMNIVEPKSAPKEPKPAYDSGFFSMTPSGKSWQPKLEQPSQFDAIPTCSCCSDIVGHGRYLRPRNLSQDVLDEWIAAEEANLSSPERFFSTPGFEFVGGHPLGHANRHHTAGYAPAMDEPAEMKTFVHKTQGTIMQRGFAVAPETRAVTAGFRADCEAARLLREAAMRARAADLRALMAGAAADWKPEAAAPLGVLAAPQYGALLAAGDGDGDGDGPDSVVPAYRSSSSSEDVRIPVSPPKVGETGLKKKVDVEGRIEFADKGEDEDGDEAVCSDDELDEDAETILARINLNRRACNAPEVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAJ9</accession>
    <name>A0A6A6PAJ9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDY21DRAFT_136296</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAJ9"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08689">
        <property type="entry name" value="C2_fungal_Pkc1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11620">
        <property type="entry name" value="HR1_PKC-like_2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.160:FF:000004">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000101">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000014">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000034">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037778">
        <property type="entry name" value="C2_fungal_PKC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037312">
        <property type="entry name" value="PKC-like_HR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15 17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 24" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="23">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="19">
        <location>
            <begin position="71"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="21">
        <location>
            <begin position="301"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="21">
        <location>
            <begin position="369"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="734"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="22">
        <location>
            <begin position="994"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="201"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="436"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="522"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="570"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="607"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="694"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="763"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF2460965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1059" mass="119086" checksum="4C0A29EC919AA8F8" modified="2020-06-17" version="1">MLSQLEFKLSVEKQYKDGIEKMVRLYELERDRKSKADAEARRIESNQKIQLLKQALKRYEDLHVDIDGADGPDDDSLSIPTQRKPLTGRLTLRIHAVADVDHATTSRFSRGPETFVIMKVEDVFKGRTKATRTDRWTDELHEFDIEKANEIELTVYDKASDHPMPIGMLWIRISDIAEEMRRKKIESEFNNSGWVSAERMGDGGPNPNLQFQPPPGQQFNPASPGSGAMGPPGASGLGNAGPQPPTGQMFIDSWFSLEPVGRIQLTLSFAKHVKDRRPFDIGLNRKGAIRQRKEEIHEQYGHKFVQQQFYNIMRCALCGDFLKYAAGMQCSDCKYTCHKRCYLKVVTKCITQSNAETDPDEAKLNHRIPHRFEVFSNVGANWCCHCGYILPLGRKQCRKCTECGLTCHAHCVHFVPDFCGMSMEVANQILGEIRNTKMRQGSARTSMKDRSFRQGGEGRPTPPPSTPSYPAPSQSPGADRYSYGSETPSRQHQHQQQQQQQPYGPSSSALNAAQASYGGPSGLPPSPEHQRPPPGGRTQSSQSSTAATSAAVAALQGKGAPQPKPQPYQRSSSDYASSPTSRTSGGYPPTFDTHPDTAQGYGQGRMQQQQQQQQQQQQQQQQQQQQQQLPQQPQYDPSKYPPLTPGYGQPYGGMPMQPPATPSTYGLPSQPQHQIPPHPPQHQIPPQHQEPLPSQTPQPQPTPEPQPQQQVIERKPQPTATAAGTGRRIGLDHFNFLAVLGKGNFGKVMLAETKANRQLYAIKVLKKEFIIENDEVESVRSEKRVFLIANKERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQRGQFSTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNILLTLDGHIKIGDYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILSDEALYPIQMPRDSVSILQKLLTREPELRLGSGPTDAQEIMSHAFFRNINWDDIYHKRVPAPFVPTISSATDTSNFDQEFTSVTPVLTPVQSVLSQAMQEEFRGFSYSADFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PAM3</accession>
    <name>A0A6A6PAM3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">REM-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_136295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2460966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PAM3"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="REM-1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2460966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="179" mass="18430" checksum="DA2FD69459BAD4FF" modified="2020-06-17" version="1">MNNEEEVIRDVNRKIEREKALITAANAMRQSTGNQAVLSRLGTQIRDGQRNIEYLEGRLREIQMRRMGSGMEGMSLGPGGGRGSGGSVGGGGGGSSSAAGGGPAPPSHDNRGDSYMDAGSYGSPGPGGYSQLSGGRGLMPPRAPYAPPAPASNLPSKPRSNYTKLGGSWPVAPETGRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB10</accession>
    <name>A0A6A6PB10_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_278992</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB10"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000266">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="68"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="521"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2461120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="620" mass="67846" checksum="B267B52E2FABF77C" modified="2020-06-17" version="1">MDVESGDSPGPTNIPHFKALLDQGFVTPEVAKAHYDGSGTVEDPYVVEWIENDSRNPQLFNPYYKWQIALAQALTTLAVAFCSSAYAGGMPEIMLKWQVSQEVATLGLSLFVMGFAVGPLIWAPISELYGRQVVFIIAFGAFTAFNAATAGAQNIETVIVLRFFSGAFGASALTNAGAVIADIFPPKERGVAMGFFSAAPFMGPVLGPIVGGFVGQGPGFRWIEGIMAILSGVMWVWGSLMIPETYAPVLLRRRAQRLAAMNPEKVYRSKVDIDHGAVSAGEAFGAAIGRPWILLFMEPIVLILSLYMSIIYGTLYMLFGAYPIVFQGERGWSQGIAGLAFIGVMIGMFGAITYSMVIDKKAYLKAVKNSPSGFAPPEARLPASMVGAVTLPIGLFWFAWTNDSSVHWLSPVAAGVPFGFSMVLVFLSVMNYLIDAYTIFAASVLAGSSILRSCFGAAFPLFTRQMYDGLGIHWASSIPAFLGLACLPFPFLFYKYGAAIRLRCTYAAQADRFMQSIRTRAAPAKEKTSDVDGAAEAAEDEDKEKREREEAAESSGRESPAEERPHFEPVRSGRSTESRREEELEYEPDPFDIDRVHTRESFASHHSHHHHHHHHHNDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PB94</accession>
    <name>A0A6A6PB94_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Mre11 DNA-binding presumed domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDY21DRAFT_279473</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the MRN complex composed of two heterodimers RAD50 and MRE11 associated with a single NBS1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001672">
        <property type="protein sequence ID" value="KAF2461210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PB94"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000011">
        <property type="entry name" value="Double-strand break repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 17" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 17" id="KW-0234">DNA repair</keyword>
    <keyword evidence="21" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 17" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 17" id="KW-0469">Meiosis</keyword>
    <keyword evidence="19" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="725"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="Mre11 DNA-binding" evidence="20">
        <location>
            <begin position="284"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="517"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="620"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="659"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00064981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF2461210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="834" mass="93725" checksum="AD750550E42292E6" modified="2020-06-17" version="1" fragment="single">ADTIRILVATDNHVGYNERDPIRGDDSWKSFHEVMCLARERDVDMVLLAGDLFHENKPSRKSMYQVMRSLRMNCYGEKPCELEMLSDASENFQGAFDHVNYEDPDINVAIPVFSIHGNHDDPSGEGHLAALDLLQISGLLNYYGRIPESDNISIKPVLLQKGRTKLALYGMSNVRDERLFRTFRDGKVRFFQPNVQKDDWFNLMSVHQNHHAYTETGYLPENFLPEFLDLVIWGHEHECLIDPRYNPETGFHVMQPGSSVATSLMPGEAVAKQVSILNITGKSFTSEPIRLRSVRPFVMRELVLQEERALKGVWRHDNNRATITRHLMEIVEELIEQAKAEWCSSQEASEHDDEEEEGPPLPLIRLRVEYSAPEGGRFDCENPQRFSNRFVGKVANVNDVIQFYRKKTNAGRRARENTNLPEESILAQMSIDTVKVEKLVREFLTAQSLTILPQNSFGDAVTQFVDKDDKHAMEIFVNESLASQMKHLLSSEDVDEDEIAEAMETYRTKLEEMFSSGHLKNKRKHLRLKPKPDNWDTDLDGDWADQPGALIHSDNEDDDVEEEEAPAPSRTTTTTRGRGRGRGRGRGGAAASRTTTAASKKASASSTTVGRGRGRRAAPVEEDDDDDVIMLDQEYDQMDEDDEEPAPVAPAPQRASRLATAGKAAAASTAASKAVPKKRATPARTVPAASSRQTRLDFVSQQPSQSQAQPRAEGRGRAVVEPVCPAWLILTLVVALEMLIMVDRVMMRSRTMMPLSLRRHRREQGGKGRLGGKGLLAAMKVWDRVRRVSMRPSCMNASALYHCVMCLSTGDLLCWELDVEEASSHEGCALISMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PBI4</accession>
    <name>A0A6A6PBI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PBI4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="329" mass="35737" checksum="738F7D21313D15EE" modified="2020-06-17" version="1">MSVGSKDHRQHVAIRHLSICRRRQVVADMLRKSFESRMEPWLPPLPRYYVSPKSKRCKADSRACGQPEREYAGDRRGLKVSLAGWLSIASVAGSPRPHHAQLRRVRTNRSAALALRWRWVRPAAAAEIWKAAPVANDGATMRRSARSRCALSISAARAMPYLPGQAARGDERGGTAARRPFIAQTGSQPFVRAWPRFLASRPASSGGWYRSGARDAVAARRVSSDSSEVLVWRAGVRVVAGAVSVAIKPGGRWTRRDAGSRTGSGSAWTGSGAGVVAAPVYSNPFAVAPIHIHMPSTKSSPDRPNAHKNGAVEFEQKRRATRSGDMLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCD5</accession>
    <name>A0A6A6PCD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquitin elongating factor core-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_368792</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCD5"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16657">
        <property type="entry name" value="RING-Ubox_UBE4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="1038"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="576"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2461616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1134" mass="126994" checksum="F133AA547565D696" modified="2020-06-17" version="1">MADSRLSDAEKIRNKRLAKLGGQGSPSGGPNATPAAPGPSSSSPQLPAAQADTSSSAPQPNPFTQLGVQQNDAPAATAAAPPATQTPPPAAQPPPPSPPQQQQQSEAAPPAAPKPRQITITPKPAASAHTPSKRDASSEPPSRPRSRQQDGRTERDSPEAWEDRTLRSIFRVTLKGQGVSADVHGNKVVAVPGVAAELREAAEEKGPQGQPLRLTVGVLEQAIFEAAQNVAATPGGNPLDYLLGCWKRVARQARQTALDKRSGQRRLEVVNEAKRLCMSYCIFAFTMPEMFEWEPPAGENQLAKHLLVDPENDRGICHDFVSEAVKRFDEDDTMKTAIVEAAEDLSDSLAKMSMNDGYKPYVLAFRNLVQFAPIVQALAGSEKFNPPGTAPEKLEKTTLLGPLFQLSPMQGEVAQNYFSSPKTRDRRYIENSQNALRMTLRTHQDELFDIVSKFIRTSAETRERTLDWFAAVVNSNHKRRAMRVDPKTTSSDGFMINVTVVLDRLCEPFMDATFSKIDRIDVNYLRRNPRVAIADETKMNADQHTSDEFYSQKVDGTNNFISEVFFLTVAAHHYGTEAANANLSTLQREVKHLEKQVEEFERERHKFSSNPQQLQLFENAVKKYKDQVERGHCIILATQGVLLDDLTQARSMQFMRYVITWMLRLVSGVQYPRQPLSLPLPAEQPQVFKCLPEYFLEDVVDNFKFITKNMPGIITSTQCEELITVCMTFLRNSEYIRNPYLKAGLITILFHGVWPLPKFSKGVLGDLLFSSPFAVKHLLHSVMKFFIEAESTGGHNQFFDKFNIRYEIFQIIRCIWGNPAYRENLDAEARDNIDFFVQFVNLLLNDVTFVLDESITAFINIHNLTQELRNPAHLDEQLKKEKEESLESAKNKAKSYMSLTNETVSMLKLFTEALVDAFTKPEIVQRLADMLDYNLDILVGPKSSNLRVEEPEAYQFRPKELLSDLIDIFINLGAKESFRVAVARDGRSYKPANFEKARSIMAKVGLKSSSEMKAWDELGKQIAAAKEADEQVEEDLGEIPDEFLDPVMYTLMEDPVILPTSRITVDRSTIRSHLLSDPTDPFNRMPLKIEEVIPDTETKEKIEAFKAQKKAEKLKEREAATAAASGVEPMDTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCG2</accession>
    <name>A0A6A6PCG2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_418628</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40048at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="8">
        <location>
            <begin position="1"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="9">
        <location>
            <begin position="400"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="687"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="10">
        <location>
            <begin position="903"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="12">
        <location>
            <begin position="1187"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1141"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1294"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1144"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1171"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1185"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1202"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1295"/>
            <end position="1305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2461618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1344" mass="147873" checksum="3E5787DB975F5B2C" modified="2020-06-17" version="1">MRNLRNIFHAETKFSDSELPLTATTWDTANNAAICAFGPTESSAVIEIKRLKYHGYKEIIQPIQSWDAPCPQPDLSCDKILSLHYFADTATICLVLAGGDLILVREDPLPGEDSIEIVGSVDAGITAAVWAPDEELLAITTRADTLLYMTRQLENITSVEFSPEDVQASKHVSVGWGKTETQFKGKRAKALRDPTVPEHVDDGVLSPEDDGYVAISWRGDGAFLAVSSIQGGKRRIIRVYSREGALDSVSEPVDGLEGALSWRPAGNLIAGAQRLKGRVDIVFFERNGLRHGQFSLPLSADELSQWGSKISIQWNDDSTVLAVCFKDRVQFWTMGNYHYYLKQEVEISPEESSLAGIAWHPEKYLRTLLRSPGSLQWLDYVFDVAAGSTKPPDDHGVVAVMDGRTLKLTPLRFANVPPPMALHEINLETNAVDVAFSRSGQRISVLHKGSVALYSYKLLGKPIPQPVLEGRCAFPDPEGCRPRQIRFLGDSKAVVVAATSFGEEIFCIDFDENQVVPFLPDEQFPSPLAAIVSRQDYEKVGLHFQDGLAKELDTNINDVGLVEAETSMVSKAPVTCPWTEFMRHGGRTLAVGLSINGHLYINDHCLTRNCTSFLLTPAHILFTTTNHLLKFIHMSAVEDLEVPPDEPEKDERCRSIERGAKLVTVIPSTYAVVLQMPRGNLETIFPRALVLAGIRRHIEERNYKEAFFACRKHRVDMNIIHDHAPEQFMRNVKEFIRQIKKVEHIDLFLSQLSEEDVSKAMYKETLKNPLVIGEHPTLNGRIQELSPQKQLSDSKINRICDAFLDALEDMKATNLRNIITANVCKSPADLDAGLLVLKEQDEDLAEDAAEHICFLADVNKLYDNALGLYNLELALLIAQQSQKDPREYLPYLQRLQEMSPLRRRFTIDDRLGRHAKALTHLHNLGTDSPFEEAKSYTSKHDLYTTALDLYKYEPLRVRAITALYATFLTSRNRFRDAGAAHDSLGDYGAAARAYRRALAWRECLAAAYLAEDMSAAERRTLAADLAGALLEARDFAAAATVLLEYLGDLEAGVRALCKGALFADATRVIALRTAGDNDGDDSAGGSSGGKKRRKELLADVLDAGLAESAAGLTELFAECKVQLGKQVPRLRELRAKKREDPLGFFGGGSGGAGGGEGDGDVPDNVSLAPTDASTAGNNSLMTRYTGRGSEATSAASSAYSRRTAKHRRKEERKRARGKPGSVYEEEYLVASVGRLIERVNSVGDEAGRVVEGLVRRGMRERAEAAARGWREVVGLCEGCVGEVFGAEEKVRIERGGGGVQDGGSDGAEVSERPQGAEGVLWDTLHGRKSWDVPVVKGVPGLCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PCP2</accession>
    <name>A0A6A6PCP2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_398090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PCP2"/>
    <dbReference type="OrthoDB" id="5418899at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2461517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="729" mass="81884" checksum="3AAEE746B8377A5E" modified="2020-06-17" version="1">MRSRTGCLTCRQRKLKCDEGKPSCGQCTKASRECVPCEGIVFRHQHNASMNGEDAGDGCNQLKGFYAYKNTFDQESVWLEIPEKVANATRVVTFINTTNPYEDEPGSPEYPGAVETPGMYSQSSFEHFRSNSWHSSSSPQKSTNGTTEPQANIELPVGAPASAPSLPPLAQLHPTAVDRHRLSPPVSMTSSSHALNFILNPSSGTSFPVYRSSPFLPSLTNRFEDSVDDNQKTVEDHEIAYLLRYFSEGPGLWMDLFDLGTYFASYVPAKAQENPLLKYAAVAYAAKAIGRVQGKKPTVGGNASRVAYTEMYADAFRVNWFDKATEYYDRALSLLRKGLHEERDIEKAGSEDDETLRWPKFVTSTDTNESAIQRKRRRLSIIPPRRTSSDELLAATAILSVYEFLDASECAWWNHLNGAKGILDVAKERMMPLQLPSPDSPVQQRLNTGISKARKATFWNIARQDMLAAFIKKTCTRLDPDDLAMWKEAGLLITQEGSIQPSNTTASGYPEGDSGSVMKEDMISNALIWLMSKLINFMASGQVPSPSSGGSFTSVHDYWHHLERLFNDWHDGLPITFKPCARISPPVKLNDELNKTLLPEVWYSIPMCASTMQSYYMSLIYLILNRPRTISGDPFDVYRRVRLEDRQLVTEAQRHSREIISIALSRPEASVRIHSTQPLYTAGQCLMDPEERRLVGQLLHDIEQDIGWATEYRVRHLLELWNRPELGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PD64</accession>
    <name>A0A6A6PD64_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_3128</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PD64"/>
    <dbReference type="OrthoDB" id="951172at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000313">
        <property type="entry name" value="Importin beta-2 subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000219">
        <property type="entry name" value="Importin subunit beta-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="32"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="356"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2461896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="924" mass="102865" checksum="6A270BDB4C1D2863" modified="2020-06-17" version="1">MAWQPQEEPLRQLAQYLKDSLSGHDVTAQRNAELMLKQAKSSPDINNYLAYLFSTNQEPASINLGPENYHAARSAAAIMLKNDIKTSYKSIPDSSKSYIRSIILLGLQDPHAQIRNYAGNVITEVVRQGGIMGWPQILSELIAMVSNETGTVSPPAQEGAMGALLKICEDNRKALDKEYQGQRPLDFMFPKLLQFTTSPIPKVRASALAAINVFVPDKPQAILMNLDSLLQHLFQLAGDTADDVRKHVCRCFIHIAEINPDKIVPHMSGLVDYMIAQQKNDSDPELALDAAEFWLCVGEDENLQMTLGPYLPKIVPVLLESMVYCEDDILKLEGDEEDAEEEDRVEDIRPAFATAKGARMASGTNGEVSGVDSNGNAKSTSDYDDGELSGGELEDFDEEDGDGDPEEQWNLRKCSAAALDVLASVFRDPVFEVTLPYLKENLNHPEWPNREAAVLALGAIADGCMDAVQPHLPDLTQYLISLLQDKEPVVRQITCWSLGRYSSWAAHLQEQERPRYFEPMMDGILKRMLDNNKRVQEAAASAFANLEEKANKELKPYCAVIVRQFVQCFAKYKDRNMFILYDCVQTLAEHVGPSLAEPELVQILMPALIQRWNKVSDQSREMFPLLECLSYVATALNDTFAPFSKPIFTRCINIIHKNLEEYWVAANNAGIDVPEKDFLVTSLDLLSAIIQALDERKSAELVATSQPNMFELLAFCMKDNNNDVRQSAYALLGDSAIYVFPQLQPYLPSILTILLEQLELSQIAIDAAETGYAVINNACWSVGEIAMRQREGMAQYVEPLLTKLGTILFNDKVPESLNENAAIALGRLGIGCANALAPHLATVAPPFLMAIRNVDWTDEKGHALRGFANIVMHNPRAMEQCLLDFMLELANAPHEFLDGLKEDGPKEVFEQVRTKGANFRIFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDB0</accession>
    <name>A0A6A6PDB0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar membrane PQ loop repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_333136</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDB0"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="333" mass="35784" checksum="6CAA4BA97CBCFB7C" modified="2020-06-17" version="1">MSQAVALAESVPLTAHEALSGVFGSVSLAAWIFLLVPQLVTNYRMRSAEGISLAFLTVWFVGDVTNLVGAVWASLVPTVIALAVYFCFADLVLIAQCVYYNVLNARRAARKASVQSGNGSATAADDDAAGSREEEPLLSRRESAASSIGLPGSHRRRSSATSSARRQHRGSQPRRDSLARIVEEGSGRREWVTNVASIAAVCAVGSVGWVVAWKSGAWAPQPSEEGREAEGMPVGAEVLGYVSAVCYLGARIPQIVKNYRDKSCEGLSLLFFMLSLLGNLTYGAGILCHSIEKEYFLRNLPWLIGSLGTMVEDVTIFAQFRIYGDKSESEAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDD5</accession>
    <name>A0A6A6PDD5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_312519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDD5"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18004">
        <property type="entry name" value="DEXHc_RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000035">
        <property type="entry name" value="DsDNA-dependent ATPase (Rad54b)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="310"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="642"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="210"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="887"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="887"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2461809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="970" mass="105952" checksum="ABA61C0717DDFDC8" modified="2020-06-17" version="1">MVLLKPFKPPLLSRRPSGSANSNASDASASKPERDDEAPSAAKRRRVDEESDGKADGDWVRRSKVVVRPASSSGFRKPLLGPANTGGVTTPSESEQRGEDGTPEGYYLVLWRKPTAKKHKTWDGDGVLAVSSGYAHLQDVSGRDLGKTTWNSPLLPGSTLSVGGKDVEVDAAISRADFMAGKPFLGGGTKITTPISTTKTSSANAKAFAPHKPLAPTKPLPSPSAPNTKATKSQFKDPLLNKTVMPRPTSSAVPQARHDPSAPGALVMKRPAVAPKGRQLVDVVVDPILSRQMREHQREGVKFLYECVMGMRPFAGEGAILADEMGLGKTLQTIALVWTLLKQNPVYEDGPVIKKALIVCPVTLINNWRKEFRKWLGLERIGVFVAEDKKTRLTDFTMGKSYNVMIVGYEKLRTIHEDLKKGAGVDIVIADEGHRLKTAQNKSALAIRALNTERRIILSGTPIQNDLSEFFVMVDFVNPGLLGKYATFKREFEGPILKSRQPGAHPKDVEKGRARSEELAALTGQFILRRTADILAKYLPPKTEYVVFCRPTSVQASVYRSVLSSPVFSAVLGSPEASLQLINILKKVCNSPSLLGRIPTESANSKENNTEDPSAQRTIATLLSSIPGSLLKSPGSSAKLQVLDSLLHHLRTSHPSDKIVLVSNYTATLDLLATLLTSLSYPFVRLDGSTSASKRHSTVEHFNRTPASSCFAFLLSAKAGGMGLNLVGASRLVLFDVDWNPSTDLQAMARIHRDGQRRACRIYRLVTAGALDEKIFQRQVAKRGLADEIVDAKANVAAFSREELRDLFRLDEGGGCRTHEALGCECGGSGVVPLDEEEEVFEKAAEDVERDTETIVPTSDRATDDEDFPDLSELLKNRPALVKANEVDMKEQERRIREQRSPATGSGGGKKGGKAKMRTLMQYTHLDASRIRGADEEELDIEALVDDEVLRDLLREDGNRIDFVFSKTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDF0</accession>
    <name>A0A6A6PDF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_375741</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDF0"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="381"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2461777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="510" mass="56507" checksum="F7DEABE1CEB200C3" modified="2020-06-17" version="1">MLHKEISGLRINTMQHSRSIMEQTVPYNPKRAQEERHSRMNSPNVYQTPTSSFSTAGFLTPSSSFEGRRDSVGSSQYSVVSNAHSLSSMSSGYSPETPGSHADVFPDDFLFPSYPAPAVMADTTMAEPSGLTVPFSPYGVAKSSAYVEPPVWGYTHHLSEAPSTHHAYHLVHTLPGSRSPAYNNMAVSNSPEFRPPFDSTLTTYPSFRHEDHTKIDVPSTTAVDDGLSAQGRKKYIDLFSNFHPRHSTPLDTGVEHHRQPSTIVPSDILMDVEMKSCNALGSDSTDSNLDRFELVGQSQDDLDDASASDDRATARKRSYQTTPTGAKRVKRDPYGSPSKRKSRAVKSTTYLNREVEVRIEGAFSVGPNGRIQCNSTPSKKLRCTRLTKEGRPCLQTFGRPEHLKRHEASTHAKERPFKCPVPGCGVVKLGGRDHKPDGGRGGRGHEKKFTRTDNRTQHYVTHSTGSKSARNIQIPFAEMCKYIIQDEGPERGAKVIERVRRQHRKAGRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDP3</accession>
    <name>A0A6A6PDP3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_360636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001671">
        <property type="protein sequence ID" value="KAF2461543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDP3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="943" mass="101621" checksum="84FDD43F2D165D22" modified="2020-06-17" version="1">MARIHSRALYNWVATQFHANPALRPRDYHAVRTQWGRHERTHVDFDERRRANLPGYSRRTAAAIARRRRRGNQNRGHGPTGAAPVAAPNTGNGQPVSGMAGNGNSQAVQNPVHQAQPTHSAGCEDDENDEDDAPGDLDDDVNDFSKAAEGENNQEDEDVEGSEQLSVSPAAVETPTEQPGLSSLAQEVEEFRASQRVGDHIGDRVEDPAEQSRLSELPSFIGLDEESLEDDNAVDSTEQSAMPSTFPFLGELNEERNLEYDSFFDPSPGFELRQATYGIPQNTTPQDATNGYNYGATEGYTDPNLADGFFNDAGYGNIGNDNFGGPVHQAMNGPDYGTTQGNGLFNDTGYDSMGNVNVDGTQYNNFMAGESMGYASTSHTGMGYYDQTQNNPGIQNGLGHDYEIQNGMGHDYLTQNGIGHGNQSLNSNSYTAAANAGMAQEETDMNASRLHQSGPLMTPPETSPEDEAFPVNLAPLNRPANPPRAQYSYVTTSTGAKKVIKKVASGTPSVGLQSASGSPPAPLNAPANPPRANCSHQSTPATPARPPSETSQRQIVDSFLNQMNNGDELSFNVNSPALTQPAAPPTPTGLAGEMLHMVPPPTPTSPIHGSSLGHRKRNDDDEDADNEDGRKAKRAKKDNDQSKAPAQANGTTLGRCRRRRRRDDDDDHVEEEDGHKMKRRMVEKDDNQAQEPAATSPTPAQAPVPEPEPDVAPAPAIALPFPEFTSIEPLDWAPTWTSGFGPIEPSVLEGTMFNDGFNFDASFFPGFETFQNYAQNGENENAGQELDGVNPLNEDHGQGAAEPTVTNTLGATEDTDHVETGMEQPLHNNLEQFPTVVPDSPVLQAEADNNFPGQLHVMLPAAAQEDSFDLLAFVGGAQPDVQEGAGTGAFDSGAPLLDNFDFDPTSFDLDAFMREENWLQDEVAQPNELESQGEKLNLAASVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDR5</accession>
    <name>A0A6A6PDR5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDR5"/>
    <dbReference type="OrthoDB" id="1731983at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF29">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="1">
        <location>
            <begin position="29"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2461897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="422" mass="47571" checksum="95430724190E65BA" modified="2020-06-17" version="1">MSLQTVQNRGIYRGLPTFPDHVKGLTAIITGANGISGQHMLRVLGQSPERWTKIYCLSRRPPMVPGGLPGNAEHVSLDFLKSPEEIAQTLKSKGVKADHIFFYSYIQVDPKPGQGLWSDAEEMTRVNVELLTNFLESLTLASIKPKRFMLQTGAKQYAIHLGPAEVPSFESDPRVTLESNFYYPQEDALFEWCRKQGVHWNVVRPSHIWGAVPDAAMNIGYPLAIYAAVQAKLGRKLEFPGDMVAWQNPVVQSNAMMNSYIEEWAVLTDAAADEAFNAHDGAEFSFSRLWAKMAEWYGTEAKHPDDNAKYMEMKSPYSPPPRGYGEPGLTRVSFTLAQWAKQPEVLQAWKEIAKEHDLMDKELHDQDRIFGFADGVSMRHPLLLSSAKLRKLGFLGYVDTIDSVREVFEHFAKFKMIPPIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PDR9</accession>
    <name>A0A6A6PDR9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_312751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PDR9"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000433">
        <property type="entry name" value="MAP kinase kinase PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="311"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="336"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="693"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="28"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="638"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2461962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="740" mass="74980" checksum="EAD99511FAF7886A" modified="2020-06-17" version="1">MTDPAAGDPVPPAGDHLDDAASYPVDAPSSPTSSSTPPLPTSPTKGPAAAGSAAGAGAPGVASSLGPPRLSPRSVSATAGMTASSTPLGNVSAARRPAAAIAQPPPTISSRNSGLNVSHDIQARMKAFHLGRQGAPPGAAARPQPAGSGCPPVVGGVPAGPGGVPAGPGGVPGGFKLPPNLAKPGIKNFQSSPAIPGRPSLAEKRGQALPGGLPGAPPALNGAPPAAGGRKKPGLKLSQMNEGSGGGDKQDGGEAGPNQGTKPQGGTMMEKYAEFLDPKTGSLRFKGKAVLNSEGVQFSTGNTFSISLDEVDTLDELGKGNYGTVYKVRHSRPKMRRPGMGLAGNKASSTLSPAVKGEENSGEAVTPTAGTSGAIMAMKEIRLELDDAKFAAIIMELDILHRCLSPFIIDFYGAFFQEGAVYICIEFMDGGSIDKLYGDGIPENILRKITLATVMGLKTLKDDHNIIHRDVKPTNILVNTRGQVKICDFGVSGNLVASIAKTNIGCQSYMAPERISSGGVAQAGANPGGGTYSVQSDIWSLGLTIIECAMGRYPYPPETYNNIFSQLSAIVDGDPPDLPAQGFSDAARNFVSGCLNKIPNLRPTYAMLLQHAWLAPLVKPATIPEATEADEAAAAADADADADADADADEEETAAAAADPPPPPPDPAQLPMATAPGVVDDEVAGWVARALERRGAGGRTGRGQAPPLHKAPLDAVTTPSPGKQPAGAGIGMGMGMGMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PE13</accession>
    <name>A0A6A6PE13_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_330744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PE13"/>
    <dbReference type="OrthoDB" id="5288586at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF2">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2462201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="60" mass="6655" checksum="1E0CA61EE3C23D7B" modified="2020-06-17" version="1">MEKTKRLLSRSRLGETVDPRRGDVALLICCFITGMVDAVTFNNWEVFAGMQTGMACATEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEF0</accession>
    <name>A0A6A6PEF0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonucleases P/MRP subunit Pop8-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_376147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEF0"/>
    <dbReference type="OrthoDB" id="5530243at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020347">
        <property type="entry name" value="Pop8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049128">
        <property type="entry name" value="Pop8-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20976">
        <property type="entry name" value="Pop8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonucleases P/MRP subunit Pop8-like" evidence="2">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="233" mass="23559" checksum="FF7A5F6FB5231782" modified="2020-06-17" version="1">MGDEQGDLAMHDAAASGSSKLPASSCEKAASPPQQPTTKPHHHRPNAGATLHQSTLRPTWLYLHLRLIYSPALPPPPASTPPPGASGPAAPAAAAAPAASAVASADLDPVVARTLLAAPLAQYLGHAGAAIALDVLKIAGRDVWVRVPDEDGGAVVSALSSWAGVVPGGGGKKKQKKSGGGGGAGAGAAGTESAQDDGERVRRRAWRIVERASWLNKLVGQGEADGRDLFDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEI4</accession>
    <name>A0A6A6PEI4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_331379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEI4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025463975" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2462424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="23841" checksum="80A8A6FCB11CD592" modified="2020-06-17" version="1">MLFLLLLLFLWLRSTLDRRFSPLLLPKLLIVIFQGDLLPRVGAAVGRARVALRLDHGRRGGRGRRSYSSSSTTDADSPCTSSSGSGADTDTSNTRLAALTLAPLALLVHLRLELEHGLARRTVEERHVLALLLVRVEGGVAAPSLGVVVGVEPEPVVAGDAHDVGRGRDVAVDALEDAVELLELVLVFWGQRSRRIGTARRWCARRHSRPEVGSGRVGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEI8</accession>
    <name>A0A6A6PEI8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_390117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEI8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="234" mass="24221" checksum="C75A83FCAA77A61A" modified="2020-06-17" version="1" fragment="single">LHPKQRLNDEALRPLPNETIEPNFRDGRRAIPSCLLSSDVELAAHPDSRARARRCHLLVGATIHGPKHVHLEIHVLQLAPGVPSPCPRHDGASLPPPASQTPPRAESPFSASGSATTQSEERSTTVSGPRPARLGPSRAAGRRRIAVHAGDPQVLLRVRARAGAAADAGPEEPAERGGEADAKDGDADDEEVLVVLGADVGGGVAAGARGRGGRRSGRGIGGHSDAGRGLQLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PEP8</accession>
    <name>A0A6A6PEP8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_330731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PEP8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="69" mass="6530" checksum="70901702E911E4A9" modified="2020-06-17" version="1">MRRAEGICQAVPSRPAGSPSDPASGDVTGHGAGSHGVGRHGAKWDGIGASASAVPCGCDGQAGAGADCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PET4</accession>
    <name>A0A6A6PET4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_368072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2461913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PET4"/>
    <dbReference type="OrthoDB" id="5229512at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2461913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="402" mass="45955" checksum="06323EB9123BC7D6" modified="2020-06-17" version="1">MAKLLDLPLELREQIYSYVVHPSPARGPECSECGTSYRYDLSLFRVNRQTYREALAVFRRENVFALLETPWQGTEQHIAIEGHVPVVATGPRASMYPYVQYHLGIRIEAPHHSTPDDNTFKLVLLMQDLPAFTRMWFYSNLTYPRLNNYLRLTLTLRNPYTSERTRTKTYAEVADMPAMAVGGRDKLPVKLQRQLLMPFGEVHNLDQVMFAGEPVDPGVEAGVREEMGRRPDSPEKCLAEAYKLKDEGNKAIKEGFYKDAIDCYEKSFLAVHIVCKGRRRSIWADAFFHTVLRGGEFHCQEGAIVRLVLRVKLVANIVLAYLKLEDYDEAYFWGMRSIRLMREAADGDDNEPMLDFVAAVEMGKIYYRTGVAAKHLGDESEARNLLRVAIQYLPNDATLVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6PG11</accession>
    <name>A0A6A6PG11_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromosome transmission fidelity protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_277082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001670">
        <property type="protein sequence ID" value="KAF2462303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6PG11"/>
    <dbReference type="OrthoDB" id="5329385at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031342">
        <property type="entry name" value="Mug163-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17119">
        <property type="entry name" value="MMU163"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2462303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36242" checksum="A185D8447593082A" modified="2020-06-17" version="1">MRRYSPTGLLARLHHAPRRNSIAPAIPAAEFGDACENNSPQRQQLSRQKRNLARVRDSKYFDASADVFRFSSTKPAASIDSGGGGPEKDTRPPNERDLKLGKTLRILRDRLPTLLTSPLPQEILSPQITLHLFPSTHPHLPTVTGKIPYTAALWTAPVAWGRVPVVGNIRLDIQSERLVRNGGALPSTLRGPGDGSAGSASYRSEKLIVRWKTCGKSKRTAEATGKHGQVDKITELLGRDDHRNSDDEFAGLFIFEFDDEGRIVAHTIEHAQEGGDYEKTTKFISVTDWLLGKAWRKPEGEEEVQPGLAMNWCDERGGKRPSSRGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NKI4</accession>
    <name>A0A6A6NKI4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_261470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001720">
        <property type="protein sequence ID" value="KAF2452250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NKI4"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051631">
        <property type="entry name" value="Ankyrin-KH/SAM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206:SF8">
        <property type="entry name" value="ANKYRIN REPEAT AND KH DOMAIN-CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206">
        <property type="entry name" value="MASK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="108" mass="10950" checksum="1FD616A5FCBF6209" modified="2020-06-17" version="1" fragment="single">YGNALQAASLEGHEQVVNLLLDKGANVNAQGGRYGNALQAASLTGHEQVVNLLLDKGANVNAQGGEYGNALQAASLKGHEQVVNLLLDKGANVNAQGGDFGNALQAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL72</accession>
    <name>A0A6A6NL72_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_367836</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001710">
        <property type="protein sequence ID" value="KAF2452408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL72"/>
    <dbReference type="OrthoDB" id="15567at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031941">
        <property type="term" value="C:filamentous actin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
        <property type="term" value="C:stress fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051371">
        <property type="term" value="F:muscle alpha-actinin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050604">
        <property type="entry name" value="PDZ-LIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24214">
        <property type="entry name" value="PDZ AND LIM DOMAIN PROTEIN ZASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24214:SF38">
        <property type="entry name" value="PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="1033"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="1177"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="525"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="614"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="741"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="853"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="898"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="914"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="937"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="986"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="996"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1238" mass="129883" checksum="D1F18554B919A0D9" modified="2020-06-17" version="1">MLHRGRSKDRNSLPSPTFMSDDQVADYLTDLRTNRIPRPTFHGARPPPPKQALPIRSSTPTAFQALSSPTSNARPLDNRNYDSGTSPLRSSSAQGHHRRNSSMVSSIISPPQPRSNSRAGRPLVQEPPYPGTVARDFSSPAPPSSPYTPMTATNGLPSPSIDAVLERAEAPAADDSGPRPSAVPQRRSFSPSLKYRESGQRWMERQEARSLRLALEDMDLQDSTRTEGATEAGEETAVEAEIERRVYDAARDEAAELVWRHQNPDAPNVYRNPDLGEETACPAAMASSPSRSTSPSVQLEGSCEPGRFDYRAHLRKGSHARSQSLGPDPAGTGAIPETSVEMPGSASRRVSLIGSLKSRRSASLASSKRSVSSGSSDSGHGGSRCASACSTRVPSDGNARMKMPGSVPEGGEGWAKEDGDEGRHADEGRDGRGRGRQSGARSASSSSSNNSRPTSPAAALVDQIMHNARQRRRSSGGSARSVSNKRKASGASLFRNPDDQIYEEPEPDSPAPKKKAQATGTEPKAAAAASNDMAAPASTTAASSPSTGTAASGSATRAEGHDASPGSPPAPVPGPPQRVAPTPSMAPNAPLQVRRNPFARVQLARESRARQQKEATTAQPVATPNGSANPNPGAEPRKDGTAEVKETTVLPADPAPPATNKDEVKDISNAGASKPSGTAAAVKQTASPVASPIARTSPFARFHRTEIHRNPPSQSRNPAYTSNTPPPSSGSAGSTQSAGPEKVEGKFESDQAEDGTPKMKNGVELRSDDIRAATSMRRRDRSPNLPQPTMVSDSPGRPIVSFQKDWKPKEVELSMAGESASDGSAGGKGTSPRQNPEITAAKRADFGAANANGKPGSRPGSSGSAGSLRGRPRGPAQPVPEINASTSSTPAPPKPSISVDSAPSVPSINVSSAPPKPKAPGPPTINVTPSPPPPVPIISVNSAPSIPTINAPDDAKPKATPPIPSIAVSDDTSNASKPTRPLPNPKSASSPNVRSSRPGPWRPAGAGAAAAPARSNTAASASTTSSMRGGSTALCAACAQPIAGRILAAAGARFHPECFRCHHCSEALECVAFYPEPEGARAARAARIRARARGEDVPADAPGEAEDGADETEVRFFCHLDFHELFSPRCKSCKTPIEGEVVVACGAEWHPFDARTPFVEKEGFAWCVGCHTNRYSAKCKKCRKPVTDTVIKALGSEWHAQCFCCVTCGGQFEDGRYFLRAETMDPVCVRCEEERLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NL99</accession>
    <name>A0A6A6NL99_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">C6 transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_359072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NL99"/>
    <dbReference type="OrthoDB" id="103819at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF25">
        <property type="entry name" value="ABC-TRANSPORTER-REGULATING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="668" mass="75042" checksum="83F9F435382FBB9B" modified="2020-06-17" version="1">MAERAHKASHRSSFLSRACENCRLRKIRCDKAIPCSSCQTLGITCQAATRQVEPRPRMVVSGQYEKQIELIQERLRTIEMSVKEISRSSQRSQSPPREDLLGQSTKGSPPASITAFEGDSSFGTSTLEASKAADLAVERVLGENQEVAAALSALRDSLQSHETDSRVHYAYLSNQQGPSKPFRADIRLLPVEFVIALVKKYKVAPPLCLVTMAAPEHIDVEKLCQKIYFPSEPIPPGSVTLMHALLYYIMRDYAEEDYSDLSEFDLATYKDICEKNLYKGLETYETLVTPTLENIQSLLLGASKAQEDSKISLCWSYVSAAQNMCQTLGYHRKSALRNDTFKVAEAKRNAFWNLYMLDKNLSLNLGRASNFRDYDIDAEFFTPCENPLQRPWDQMALGWVKFATVQGEVYDQLYSAQAARSPPEGRLRAIQELSSRLLTVRDEIVSVDYSRGYFCEYVCCMDAATDFITYSVLTIIYRAQAIQGHGTEISGKCFEAAKLSLQNHLRCFEDFRRLGGSKQTDYVNWVLLYPSFTPFVIVFTHAIGTTDLDDLALLSETVHSLDMLKHLCHGSKRLFNVCKAFLNAAEALINSRQTLSGLHQHDNGSLVLSPGTNPQTQQMPISDFVWPTEDFNFGASNMDMSAFLSGWLGANRPVTEMLNLEFGEHDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLB5</accession>
    <name>A0A6A6NLB5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_294604</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001708">
        <property type="protein sequence ID" value="KAF2452515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLB5"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="4">
        <location>
            <begin position="40"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="288" mass="32475" checksum="9AB371A7DB75FB06" modified="2020-06-17" version="1" fragment="single">SCIPCPPLDSPSFGLIQEKFADNPFHLLLVVYFLNKTKGTAAIPSFFSLIERYPTAEDLAHASEADITEMIKPLGLQNIRSRNIVIFAKKWVSDPPQAGKRYRTLNYPRVGDGRDIKRDEIVADNAEDPREGAFEIGHLPICGPYARDSWRIFCRDVQRGIADGWNGEGRSGMFEPEWKRVVPSDKELRAFLRWMWLREGWDWDPLTGEKKVASSEVLDKAKQGDAEWVDPDEGTSKQQGDKNAALALAREDRAPCETIGEARDSRAARLRPNSTKKIVVVEIDAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLN9</accession>
    <name>A0A6A6NLN9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_358732</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="MU001706">
        <property type="protein sequence ID" value="KAF2452635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLN9"/>
    <dbReference type="OrthoDB" id="440160at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2452635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="285" mass="31484" checksum="57A15E9AA50EE19A" modified="2020-06-17" version="1">MNTYVALASLPILIVVFWMYTAHIFSRTPFNLHNKRILLLIAHPDDEAMFFAPTLLSLTRAELGNHVKILCLSTGDADGLGSVRKHELVKSGLALGIRSENDILVLDDPNFPDSMDVTWHPRLISNLLTTTFAPNMAKIPSDKRPEASIDAIVTFDAGGVSGHPNHKSLHAGAHAFIRALMHRHAGWDCPVKLYSLTTTNIVRKYASVLDAPTTLVTTMLAKKDAGSASGGMPSPLVFLSDVSGWRRAQGAMTTGHKSQMRWFRWGWIGLSRYMVMNDLRREKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NLZ3</accession>
    <name>A0A6A6NLZ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mss4-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_358213</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001704">
        <property type="protein sequence ID" value="KAF2452745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NLZ3"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052355">
        <property type="entry name" value="CENP-V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620:SF1">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620">
        <property type="entry name" value="CENTROMERE PROTEIN V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="11"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2452745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="129" mass="15020" checksum="EDC1E31C27314FB8" modified="2020-06-17" version="1">MTTEEKPSKVYDGSCQCETVKYTVKISPPIPDWEVVSCNCTICSRNGYLFVYPYFENLHFVSGQDNLRMYTYHRKWIGHYFCTTCGSSIYAKSHSEKFHPEVAAVNVRMLDGVDLKSLKIQEVDKRDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMC7</accession>
    <name>A0A6A6NMC7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="4 13">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_293983</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="4 13"/>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMC7"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12173">
        <property type="entry name" value="PGDH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.90:FF:000003">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000021">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000008">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF22">
        <property type="entry name" value="D-3-PHOSPHOGLYCERATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="Serine metabolism enzymes domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="14">
        <location>
            <begin position="21"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="15">
        <location>
            <begin position="123"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="D-3-phosphoglycerate dehydrogenase ASB" evidence="16">
        <location>
            <begin position="351"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF19304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2452892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="601" mass="63852" checksum="0D6A7BD2F62ECC64" modified="2020-06-17" version="1">MPIPASPAADLSTRPIAVPKVLIPEKVSSDGLELLRSSSFDVHERKGLSPDELRDIIADYDAIIVRSETQVHASLIEAGKKLKVIARAGVGVDNVDVTAATRNGVLVVNSPSGNINAAAEHTIALMMAVARNIPEGYAGMKAGKWERSKLVGVEVKGKTLAIIGLGKVGLTVARQASGLGMRVIGHDPFANLELCAAANVAVHSSLSSMLSAADFLTIHTPLIASTKGMVGKEEIKLMKKTARVLNVARGGTIDERALLEALDEGRLAGAGVDVWTTEPPWKSPEGEDSVAVRLASYPKVVCTPHLGASTVEAQESVSVDVCEQVVSILCGELPRSAVNAPLILPEEAKALQPFVDLVERMGSLYMQYFSMRGSSTSTGELSNARTTFDLTYGGAVAQLKSTRPLFAALVKGLLSPLSDPGAPVNVNIVNAELVTRERGIAINEHRDREADVREKGYSSFVTLRARVGRGASQPRQGVDRKKEREHFIQGFVSGGAPYISRMDRFRTNFVPLGTHLICRNFDSCGKIGFVGSRLGEAGVNIRFMSVAPALGDDEDGKGAMESGDANNEALMILGVDRPVEGEVVRGLISEKGVLEANVVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMI7</accession>
    <name>A0A6A6NMI7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_357902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001702">
        <property type="protein sequence ID" value="KAF2452921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMI7"/>
    <dbReference type="OrthoDB" id="3641511at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.70">
        <property type="entry name" value="Designed single chain three-helix bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2452921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="23135" checksum="7C7DD721A18BE727" modified="2020-06-17" version="1">MAAPDAYARPDFAILNRATRDIGTELSKLANLPVIDEGGRILESIQQLTQAVAQLSGRIDALSNNVDQKINTLSVSVDQRFEALNQKIDQMDQRNRRMLKALRVQSTQDILLAFCTLTCRATQRLQQQSPHLERDRTAPRYQPYAPTHTVDERAYSWLPPEGRQYHVHEQRRYRSRPKSTRAAHRSDPPRKAGTTEELHRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NMR8</accession>
    <name>A0A6A6NMR8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_356959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001700">
        <property type="protein sequence ID" value="KAF2453001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NMR8"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2453001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="57" mass="6300" checksum="2B56BEF11EDC2820" modified="2020-06-17" version="1">MKGCSINKTLREELSTSRRACEEKVGDSRLGGCRHVNQLRTQQYGGCAVSLRDKGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NN58</accession>
    <name>A0A6A6NN58_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vezatin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_294354</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
            <location evidence="2">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vezatin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001705">
        <property type="protein sequence ID" value="KAF2452683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NN58"/>
    <dbReference type="OrthoDB" id="21151at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017022">
        <property type="term" value="F:myosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026859">
        <property type="entry name" value="Myosin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026858">
        <property type="entry name" value="Vezatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15989">
        <property type="entry name" value="VEZATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15989:SF5">
        <property type="entry name" value="VEZATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12632">
        <property type="entry name" value="Vezatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0965">Cell junction</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin-binding" evidence="15">
        <location>
            <begin position="162"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="447"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2452683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="683" mass="72308" checksum="15C6C0BA8E3E8DC4" modified="2020-06-17" version="1">MENVIYEDTPLAAYLEGEGKAESTSAPTVDWNTVPQDSPGASPKTQQSFAPRGPSTLQSRIKGKLPAPLRVKVPAHGPVARIHTACSRAVNSRLGRADNARFLEHFRYILITSQLLSERDSAGGLLAPTATSAVSGSFQAPEFKATTITVTGASVTAASGLVLAWLIHWARDAETSGLSGGRVSLVTLMVVAVTAVFYGYVRRQWLQHLRQQAVDAASALVTNIQAFDASTSAALTLIQEVELVSRGYRISSPLPPISRLEEKGQGRRCARLRKSLRNAFVSAIPSVTEAFNSLKPLVLEDDFEKYLDVYDITKSDLHEGLLGCSESESEDLEALKILRIYQFRLSILRRVFLCSLLALEADGGKLDFARWREAVHAMETVASIMGKHSEKLNNILTEEEQFTLPPTPKAPVTPGRARVRSQIRKLGSLSQGIRGLQAKLQILREESAKSLDGSSSGGGGGGGLAEPTSPPSAGGSPPDADVSDAAAHLMAQYDSIGADLRALLQAWETGRASLALNVDRATSSGTDALFQRRASAASRSSSAGLRSPVPSLGGLTAVDELSAGAGVGAGNGSGSPSDALRALNGEATGAASGSSVENSAGGSGASSSDEEIFEAMAIPKTRGPGLFQLSREERVAKVAEDRARQAARREQREASSNMLRELQSVIELRPGAKRAHGQRVTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNH5</accession>
    <name>A0A6A6NNH5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_128738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001698">
        <property type="protein sequence ID" value="KAF2453315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNH5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="216" mass="23608" checksum="F83C38F51608CBFB" modified="2020-06-17" version="1">MPLDRRGQTCQTGRLGRQGAARRGEGFRNFLGTGTPAAKFFARRPRREKCALPGGGRRVECVVTSLRRLIRAPALGTREHPDTVSIGTGEACTQDAPPVSAFPLAFQHRIADRTADARPGVSLHRAEWRRVRATSALHEAKCEEKAADTFFSKSPPEKIPAMLSWGKRLSGQVLDFIQRSTPLAVPTIPVPLDWGPLTLSSPSPLSVRAPARPTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNP6</accession>
    <name>A0A6A6NNP6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_367396</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNP6"/>
    <dbReference type="OrthoDB" id="3996471at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF112">
        <property type="entry name" value="RNA EXONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="6">
        <location>
            <begin position="496"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="280"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="658"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2452994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="803" mass="84281" checksum="BAE411D827D30E68" modified="2020-06-17" version="1">MFTPKGLFRTIPCPKLPACRLPNCLFSHDPAVAGASCGADPDADPRPDAESGTAGTSAGGAAGLDALLRARRPAETGLDHGVEAREPGRGAEGEGGEEEGGAQEIGRKRRRVEGKGEGEGEREGRVLKSALRSVSPPPTTRKTTTTKAPAKQSSAASLSKQPSLAATKQQPPKKKESLNPRSLSAASPAPHQTRLILVHKLHETLSKINMQAMASKEASVRALVLSEDELVTRALDEEERVAKGEGRAVYGNLVKQRIVALSKMGLDGWVKEESVRREKVAAETAKEEDGTAESAHQNGSAGTAGKAMPNKSTPATPKPPPLLPTYKPSSEAPAITTNLTPARERVMLAHFARTISTLYFPTLPAHGYILDPPSQSAIDDATATVAMAAGFETCDRCASRFQVFPQRRADDGAVATGGACTFHWGRAVRPPRAKAAQAGASHADAEPRHACCDARRGEPGCARAPTHVFKTADPARLAASTPFVRTSPNDDVPGERAVALDCEMCYTAHGMELVRVTAVGWPGGELMLDVLVRPVGAVLDFNTRFSGIAGGAWGRAREWSEGDALVPEEGGGGDLLMASSPAHARALLLRLIAPSTPLVGHALENDLAALRLCHPSIVDSVLLYPVPGTALPMRFGLKRLVRETFGREIQVGGLVGRGAGERAEGKDAGGLAEADGEGEEEVRGHDSAEDARAAGWLVRAKVGAWWKRLEAEGWAWDGERLVAPPSEAERARERRLGEGEAVAGLDAEAREVNPFPKGFGGLRVEAGGTVAGKKRGRAGTAGGGSAQKGAVVASVTGVVRALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NNU5</accession>
    <name>A0A6A6NNU5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_357542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001701">
        <property type="protein sequence ID" value="KAF2452973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NNU5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2452973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="61" mass="6614" checksum="8300A914775908FA" modified="2020-06-17" version="1">MRDPGRQGRPTRKAPFSYPHLSLLPRARARGAKAEGDALPGPGRARPAFRGPSHFNNSLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NP42</accession>
    <name>A0A6A6NP42_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
            <ecNumber evidence="2">1.3.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_327626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.72" evidence="2"/>
    <dbReference type="EMBL" id="MU001697">
        <property type="protein sequence ID" value="KAF2453448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NP42"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000246">
        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050614">
        <property type="term" value="F:Delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000031">
        <property type="entry name" value="FAD binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF10">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14300)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="508" mass="57206" checksum="37073163DE6807C6" modified="2020-06-17" version="1">MERHRKAVSIIASTVRQFFERNEAFRIAHGSSNTTRPSKKGHTVDISQLKNVLRVDTDNRTALVEPNVPMDRLVESTLKHGLVPPVVMEFPGITAGGGYAGTAGESSSFKYGFFDRTVNSVEMVLANGDVINASRSQNADLFTGAAGAVGTLGITTLLELQLIKAKKYVKATYSPTGSVRETVQSIFKETLNPTNDYVDGILFSKDHGAVITGQMTDDKPESLQVQTFSHPFDPWFYLHVQNKTQRQTEPVTEFIPLAEYLFRYDRGGFWVGASAFSYFRFPFNRYTRWFLDDFLHTRMLYQALHASGESSRYIVQDMALPYSTAEGFIDYTSSAFGIWPLWLCPLQQTPPPTFHPHTGGETAAAAAAPNGAAPRPMLNVGLWGFGPAEPDAFVAANRALERRLRDFGGMKWLYAHTYYAEDEFWRQYDRGWYEGLRRKYHATTLPSVHQKVRIDVEADRRERAESWGRWARSFWPVGGLWGIKKAIASGDYLLARNSTWKWKSGSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPH6</accession>
    <name>A0A6A6NPH6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_292294</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPH6"/>
    <dbReference type="OrthoDB" id="4078873at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000335">
        <property type="entry name" value="Siderochrome iron transporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000284">
        <property type="entry name" value="Siderophore iron transporter mirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2453695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="587" mass="64776" checksum="1B48B3231E27F4DE" modified="2020-06-17" version="1">MSLPSFLEKHRDPTPVDEDTKKPIDSEANINVQEQRSDDSERISEDVQAGVQAIQATATVWTTTALIIAYIMIFIIYFVDSMQQNVTAALNPYVTSSFALHSLTAATNIMSNIIGGLFKLPLAKILDIWGRPQGYFAMIVVLTVGIVMMAGCNNVETYAAAQVFYWVGYNGLGYSLSIFIADTSSLKNRALMFAYSNSPYIATVWIGGPIAESVLGGAGWRWGFGIFAIVTPAVTLPLWGLLAWNHNKAKKLGIIHRRNSGRTFLQSVKYYAIEFDLFGLILIAGGLALFLLPFSLYTYQGEGWRAPMIICMIIFGGLLLIGFGLWEKYWAPKTFLPYDLLTDRTVLGACILSGVLFVAWYIWNAYFSSFLQVVNDLSVTEASYVTRIYTIGSCFWAVVVGLLIRWSGRFKWLALYFGVPLTILGVGLMIHFRQPNTDIGYIVMCQLFIALSGGTLVICEQMAAMAVVSHQYVAVILAFEGMFSSVGGAIGSSISAAIWTGVFPDRLARYLPADEMANLAMIYADLETQLSYPVGSPTRDAIQQAYGDAQKYMLIAATAVLSLIIPSVIVWRDIQVKDFKQVKGRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPQ6</accession>
    <name>A0A6A6NPQ6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Class E vacuolar protein-sorting machinery protein HSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Class E vacuolar protein-sorting machinery protein hse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_424213</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the STAM family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPQ6"/>
    <dbReference type="OrthoDB" id="10255964at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21386">
        <property type="entry name" value="GAT_Hse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11805">
        <property type="entry name" value="SH3_GRB2_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16978">
        <property type="entry name" value="VHS_HSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929:SF3">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="15">
        <location>
            <begin position="16"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="14">
        <location>
            <begin position="220"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="176"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="376"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="540"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="592"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="637"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="701"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2453780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="730" mass="77360" checksum="6A5C80910B414321" modified="2020-06-17" version="1">MFRQQQNAFDDVVVKATDENLTSENWEYILDVCDKVSSGDNGAKDAVAAMIKRLAHRNANVQLYTLELANALSQNCGVKLHKELASRSFTDALLRLAADRNTHQQVKAKILERMQEWTNMFSRDPDLGIMEQAFNRLKAQNPNLRPPSKPQKTQITDADRRKEEEELQMALALSIKDKGQGPSNAQAAASGAPSDGTHRQESQQQQQQQQHLPSGGTTAATVSRVRALFDFQPSEPGELQFRKGDIIAVLESVYKDWWKGSLRGQTGIFPLNYVEKLQDPTKEEIEREAQMEAEVFGEIRNVEKLLALLSTGARPGEPADVRDNEEITNLYHKTLSIRPKLIELIGKYSQKKDDFTQLNEKFIKARRDYEYLLEASMSHPPPPQAQLPYRQSYAPPQQQSHGRQSAYSPPYGGYGAPPPSQPQQQQQQPDPAQRYYTSSPPQDVAQHQPPLAQQQAQQPPQQSQQQQPQQQQPPYPPQSGPPQPFYMMSGPGGAPPPQSGGPAQPPSAAAAAAAAAAAASATGRPSPGPGDLYAGPPPSHQQHQQHQQPSHQQQRYGAGAGGRPLSAAYPQELATQVYDSPVDGRTGAFVPGPGPGPGPGPGRPVTMYDDSPSSMYSAHDGALGGTGGGYPSLAGAAPPPVGASASPPPQQQQQGGGGGGGGVPGAPAYMGLPSQAGPGGAGAGAGGAGGGGGYQAYHPEAGGGRWGGVGGGGGGGTAAAAAADGEGYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPQ7</accession>
    <name>A0A6A6NPQ7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_354803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPQ7"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="127" mass="13610" checksum="00C76664A7ADF0E4" modified="2020-06-17" version="1">MAILRIGMGQYAEVAGMHRDDFIRLVCGCLSCGSTCGCAIWAYYLVGFRETIKSVLHSFIISIFLIEHFVVVSGLYTIASASSGSLLTFIMLSCYRSLGRVVQPSRGPCGGISGLPRETKASLSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPQ8</accession>
    <name>A0A6A6NPQ8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_123690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5242853at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1221"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1248"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1275"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2453668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1285" mass="145516" checksum="6AC82847D2795740" modified="2020-06-17" version="1">MDPISVVGIAGSSVQFADVGCRALLGTLKFLKSLRDIPRRMETLLQDIDKFVLRISGLQSEIRRPDSTLFSQISAAQRQRLEVVVQDAYQTVEDLQTALIPLGRHTTPGSHTKVKKAWRAVMSVKEEDKIKEMLERIERLYRDVTVELQRTGLDAQAAMSTCLLQIQADLGAHGQSEIDHFDQLRSLIEDMQRQTRESSDNLSEVKAQARSAAATVNECDTSIKALVPSVERIENTAKFLHEDVKEIRAQQPDNSHLLVQLQATYRQEAGVTREEFQSLRNAVLLSLSERSNTFSDSDRAAAGRLSDADNFSLTAAVGKELVSHPGTLKESCDFVYSHAYPIYQFGQVSERPCNCVARRRRDWTRRGRFAVVYQSRATHDQQCPFYEMTGWSWSYRFSAQLLPFLRKTVELTLGAGSGGRSPGLTSSLRFYGTVKRSESPIFQAFDSIPKLCASKTYAEYSRFHFVDDRGTFVYKWDCTRVKEELSGLCQRLWDILTSGSASASDKDENGNTALHGILFLVSMLGGEYRHVVPELDQLILLVVEAGVDVSAVAYVHDHRWVTTCTRLVRIGTYSYPVRAADLGGALALEGSQLQDRLSEALERCNILEPGTLAEHSILPYGARFPCSSRRQYLALFKRRPSALEWYGYGPLEHAIIIRSRQEVQRILQKMQQHNAADNARWLHARHPAYDFDFSFPRCRKCKSNNFNDEDDGDESDYDDGSGRYDDYCNASESNDIFQRLRNLLSPLECALGWPDGLQALLDAGMDSRLALNLAIDMGDLESLEILLSADFPLTTNGSAVWDLLSHALSYASPEIRLCVVNSLKDRRNRLTDLALRELTAEEQAEVGLPIERTLDANAFGVYNTLRKKGVKVPDALYPSRMSSVYDMDLQCCNVELLDMLFEAGFQDVEVMNTFGETPVTFCFTNLGDIYFGRGWTKLVRKFLDKMSNLAFNFPFSYPNMLFYLASLEPWMRRRRLHPWYEDDRSELQGLVQDSASLCDPLEPDTCLCFCSSNGCTPVHMFRYDLSDLWVVKAAAKTYMEDVAAEWVELCGLDSSQSEFCYRELCRLETFDRLGMAHTCCGSQRFHSHGIIRNMMHDSKRVEIQAEDSELNEQLELLLAAYDGARQKEGGEFGHFWSRWWRRVDQILPEPLAEERIRYRGLDWEDSVYNSQAHQEADAKATQRRAEREAQAVEWCGYSGMDFIDIIRKHFADVLDADQGEYHASEPESAQGCETVWTSPGSTAYPAPVREKDAPGRERGVLAGSDATDCPGRSGQPRKLRRVKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NPU7</accession>
    <name>A0A6A6NPU7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">endo-1,3(4)-beta-glucanase</fullName>
            <ecNumber evidence="4">3.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_116953</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;3)- or (1-&gt;4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.</text>
            <dbReference type="EC" id="3.2.1.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.6" evidence="4"/>
    <dbReference type="EMBL" id="MU001695">
        <property type="protein sequence ID" value="KAF2453708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NPU7"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000114">
        <property type="entry name" value="Probable endo-1,3(4)-beta-glucanase NFIA_089530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF58">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE XGEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025481155" description="endo-1,3(4)-beta-glucanase" evidence="14">
        <location>
            <begin position="25"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="820"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="15">
        <location>
            <begin position="31"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2453708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="839" mass="86653" checksum="65F1CA563638DC64" modified="2020-06-17" version="1">MRSSSLISSVSALLLSSTFDLVSASPFQRRGESSTTDYELEDVFKGYDFVTDFNFYSGDDPTHGYVDYQSSSAAQSAGLVYINEDGSFHMGVDSEQVLTTDVRGRKSVRIESAQRWTQGLFVLDLKHMPGSACGSWPAFWTLGTGDWPNNGEIDIIEGVNLMDGNQMVLHTDGDCTISGSGSKATFLTNDCSIEAGTAGCAFLDSPPSFGTKFNQNGGGVYAMEWTSDFIKMWFFPRGSIPPSITSGHPDISEFGTPSGLFEGSCDIEEHFTDHQIIFDTTFCGDWAGNVYGDSGCPMTDDDPIASCVNYVAGHPEAFEQSYWEINYLKIYKPEVEPTSSSSSSSASSSSVSATVSLSMSTTSSASLSTSSTYSNSSSFSSTFNSEVPLASSTSLAIETVSDANGRPSSSSSTSSSVAATGSSTISYSHTDGIYTNSSIGSTGSSTISYSHTGGIYTNSSIASTASTASYTDSYTDSYTDSNTASNTVPYLSTITGSPVYSDSSATVATSASKETVTTVIVTSYVDVCPTGYVTSTITQTVTYCPADQTPGAPPPGMTTKVTLCAHGCGPAPTSVTLTVPCETATEAETPASTTPASPVETGPVETAAAGHATHVVYTTTVITVTRCPPSVPHCPADQASTELVTTSVPAYTTTVACAAGSEEECYGFDYTAAPPATYTPPAPSAGPETPVASEYPAASEYPVSSEYPVGSEYPVSPETPVTMVHTVTMMPMPVASYSAPAPEAPYCEGAGCEEEASPVAPATSEAPCYGPGCSPSPSPLNTVTMSLSYGNWGNGSATMPTGSGTLGAPVAEFTGAAGRVGAGVVAVVVGVVGVMAVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQJ0</accession>
    <name>A0A6A6NQJ0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_417193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001696">
        <property type="protein sequence ID" value="KAF2453682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQJ0"/>
    <dbReference type="OrthoDB" id="512662at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF4">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY FAMILY (AFU_ORTHOLOGUE AFUA_4G09540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2453682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="251" mass="28964" checksum="35F20D24D34A7D9A" modified="2020-06-17" version="1">MPIEVSRMTEADVDSAINTVQQAFADDPYNKWIYDDRSKFSPARNRVSLGLRCRWGIQHGLFYVAKDPASATPDKVLGTAMWLAPRPAAEPESWSLYLSYWRLWLSQVYMNAVYGRGGLNVKRYWIWKARQKEAQEALWTDPRGYYFCNIVTVLPEAQRRGVGRKLMEVVLEKADEEGMPAYLESSRNEPNVPIYEKFGFKLVREMECDDDGTGIQLYCMMRDPKGVKSSDDEEPVPVYLTIGKRIRIRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NQQ2</accession>
    <name>A0A6A6NQQ2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein AF-9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_111340</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NQQ2"/>
    <dbReference type="OrthoDB" id="16041at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573:SF1">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="7">
        <location>
            <begin position="9"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2454061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="310" mass="34125" checksum="A1C234340D6C598E" modified="2020-06-17" version="1">MPAPAGTKRVKGKRISRAFIIGSEAWPLPPVGSPQRPANVPDDHTTQWRVYVRGMPGQPDLTTWLKKVQFKLFHTYMNPLRTVDNAPFVVSETGWGGFNVEIRLHFNPASGEKPQWRQHFLQLERYGSDEDRARQEREGVVRSEFVEWIEFNEPTEAFWDEMTADSQWAYLDADKTAAGPSGAKGSGGRGKGATSTTGTSLGGGTAGVKDGKVNVGSGTPAGGPVGVDGIERTSELPDKPTDYNDISLAMEADVMAIIRQAEAEIDKQMAKELERKKKMDEELKKLKEDGATVPVVEKTPATATSERRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NR34</accession>
    <name>A0A6A6NR34_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_374475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001694">
        <property type="protein sequence ID" value="KAF2453967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NR34"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF3">
        <property type="entry name" value="(3R)-3-[(CARBOXYMETHYL)AMINO]FATTY ACID OXYGENASE_DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="15"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2453967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="324" mass="36767" checksum="228611DE6F6C0F10" modified="2020-06-17" version="1">MPGIIKDTPFKTISVKELHPTFGAEIEGVDFENLSQEQFDEIKAALAKYGVCVFRNTGMDDDKHVEFSRRFGELDDIKRYMQPGAKLRYKYYELFDAGNVDENGQVVDPESTRAHYNRGNLLWHVDSSFNPRRASMSILRAYELPPAGTGGDTEFADSRSAFDALPEDLKQELLSRDYVAAHSHAWSRKKGSPDFFKELDPTGSKMARHRLVQRHEPSGRMNIYTAAHAHHVEGLSQDESDKLLDTLAKHVTQPRFVLDVAWQNPTDLIIWDNTCVMHRAAGGSFEGKYRRDLRRTTVHDDSPTAWGLNEKDFAPPGLMARRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRH0</accession>
    <name>A0A6A6NRH0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_113513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRH0"/>
    <dbReference type="OrthoDB" id="4738706at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="65998" checksum="8A00BEF44306CAE0" modified="2020-06-17" version="1">MSVLGIDFGSFQSILTPPSSTNVSRSSSVNTGKQNGLPDEAHEAVTGAQLPSANAFKCTAAGIRGSLDDHGIPYPRYKDQQYQSPNLPSHGHSYRRRSKSGACAAGRLAQLSNFCLGINFLAGTSCYVAFHKLTATGPVRQGRRGSKTLPSARDVIGTSFAEQDDPSSSSADSAAEYASSSEASEDDDGWYEAHPSVTIPTQKKVEKLVRKAKWAIHQSSFTQSVGQKMQASSGDETPSSGHCSIRGDSASRKGNGRPTLEESQPHDDEQDGQPKKRRKVKPVPESDLPASPRFACVFFKHDPERYKSRRTCAGPGWATVHRMKEHLYRAHAQPIYCPRCYKLFDADTELSVHLRSEPCEISTSQSIEGINREQLSKLRKRTTHCRLEEDKWRDTYHILFPEVLEEDIPSPFYDGDSPAEQSRQFRRELLALIRTELLATAEREPRYVEERLLRQVAGIVQRCQNQLLAERNINTPTSTFVLRQPQSQAESTVTTSPPEISTTTSAIAPQADEAEILAIMPNVSPIRSAPSIASGSPHLSVQMSRENEQVESGGPRSLTNPLDTVGHELSEIDWNTVFDPAPEEFPLFWPPEAQTISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRL0</accession>
    <name>A0A6A6NRL0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_374240</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRL0"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000019">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000006">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000771">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="12">
        <location>
            <begin position="1095"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2454349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1272" mass="140479" checksum="2C2A4DE220A14885" modified="2020-06-17" version="1">MPRGVEGNEVASTPKPSSAKGAKKGTPTLQQQSSGKTQQRSILGFFAKKPAAVPAAENASSAVRSSSPVEAAASSPMAGKGIGNGGKVALRKDRADIVTPVPSSDIGDVGDDAVLSSAAGKRNGTFNKENGLLPSPVTPSGLDGADERGEEPVKDEDSDAVMASSPPRKARKSVNYAESDQEDDEDEEVFRPISANTTKSRVSKRRKFISDDEDEEFGIDGAADDVDEDDMDDFIVPDDSDAEVVPKKRKRKSAGASKPSKKSSSPPPVNEDEDGDLDMPSVSTAQQWKFDPANIKPSTSSARPKPKRAPSSQEKKPKAHTTEPEQRYPWLANLRDADGNPPGHPDYDPRTIYIPPLAWNKFSPFEKQYWEIKQKFWDTIVFFKKGKFYELYENDATIGHQLFDLKLTDRVNMRMVGVPEASLDMWANQFVAKGYKIARVDQMETALGKEMRERDAKPSSKVVKSTGKDKENKVIRRELSAVLTAGTLVDGGMLQDDMSTFCVAIKEFEKDDRPVFGIAFVDAATAQFHISEFVDDVDMTRFETFVAQTRPGELLLEKSCISARALRILKNNTSPTTIWNYLKPGKEFWDADVTIRELDANDYFVSEDDKGAQAWPAALREAKQKEMAMSAFGALCQYLRMLKIDRDLVSLGNVSWYDPIRKATSLVLDGQSLINLEIFANSFDGGVDGTLFAMLNRCVTPFGKRMLRQWICHPLADARKINARLDAVDALLADPSVTQRFTASLSKLPDLERLISRVHAGRCKPSDFVKVIEGFEQIDYTMSLLREFGAGDGVIGQLISSMPDMSKILRHWKDAFDHEKARKEGLLIPAPGVESDFDGSQEEIDDVLQRLDKLLHDARRQFGSSAICFRDNGKEIYQLEVPIKIKNVPKSWDQMSATAKVKRYYTPELRKLVRELQEAQETHGQIAKEVAGRFFARFDEDYATWLAAVKGVAHLDCLISLARASAALGTPSCRPEFVETGRTTVEFEELRHPCMLASVQDFIPNDVRLGGESPNIDLMTGANASGKSTILRMTCIAVILAQIGTHLPCTSARLTPIDRIMSRLGANDNIFGAQSTFFVELSETKKILSESSPRSLVILDELGRGTSSHDGIAVAQAVLHHLASHTGCVGFFATHYRSLAAEFEPHPEVRAVRMRINVDDEARRVTFLYRLEDGVAEGSFGMHCAAMCGIPAKVVEGAEEAARRWEHTSRLGESVEEARRKRIGSGADGEDQGSCYFPLGMQSDVAWYLREDLAEWGGQRGLEVLRKAIESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRR8</accession>
    <name>A0A6A6NRR8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_309540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001693">
        <property type="protein sequence ID" value="KAF2454112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRR8"/>
    <dbReference type="OrthoDB" id="3533814at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502:SF3">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="2">
        <location>
            <begin position="78"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="362" mass="41710" checksum="AFF5D5FF6EDF1AD9" modified="2020-06-17" version="1">MNMAPCAYESSYFPVFPVPSNLKRLWLKEPSFAKACPPLGHLGVPMTNSTLLPLFRQQPPHLPPRTQYLSIDNLDGLPRLAAFQTALPYLSLYRRFGYLHARLLVDLQHQIRELENRLLKFDKYDVGQDGNRLRIQCSMKDIEDSEEEHGFGIEINRRQCLKELQDRLSEYDDLLIKTNTLASFNRPSAYGYASVRNWINDNRPLRGLGRDFIEWKEDLVTLGQPCEWALLDKLLMMLLPKIERWPIIESIFRPRDLRRKTADPRVHLYCPARVEFVASILLTLLICILLIIPVLVLFHLNAANRTNAVRDSVIVLSVFVFVFVVAMSWFTKARRSDVFAASAAYTAVLVVFISSFLETKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NRZ8</accession>
    <name>A0A6A6NRZ8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_423847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NRZ8"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="399" mass="44615" checksum="E76ACE0C2E2AB127" modified="2020-06-17" version="1">MVLEERHTLISATAIVQLHDAVHGYVYIRNSSSIAPTYHAAIKFRWPPVDASTDGREALRAGPSSHRAFQSHPSRKTHQARPVDRVSASSRKYDEIERQLGRDEALSEYVKDKIRYDYNRGSNRLVIRMPIGVHEFFIDGVEDAIRSQLKTIRSGSDTAAGFAQRVRAARSSEIYFPIDDAPGGTKSKYGPDASFWHDDAEYPGVIIEVAYSQKTKRLARLAEDYLLDSDANVQAVVGLNIGYGKGGSRKATLSVWRTRVFNTADGNELRIAREVADDIFRDDQGHPTDHPGLRLYLSDFAHAGLARVQLGSHNRELFISTEQLCEFLTAAEVKVHQRGSLSKDQLAPGVKKRKRLETPPEEVTSEDEAVYAEQEERAAKRTADSDPDYQDTSTKSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS17</accession>
    <name>A0A6A6NS17_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Opsin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDY21DRAFT_107772</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001692">
        <property type="protein sequence ID" value="KAF2454244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS17"/>
    <dbReference type="OrthoDB" id="10261467at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF2">
        <property type="entry name" value="BACTERIORHODOPSIN _OPSIN, NOPA (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00327">
        <property type="entry name" value="BACTERIAL_OPSIN_RET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025356712" description="Opsin-1" evidence="13">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF2454244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="31731" checksum="6C23C93145B53C67" modified="2020-06-17" version="1">MLVATLLFTALSWMIPVVRTPIHPRHQHTIPTSPPINQTPSPTPLSFSPLARPQSKRIFHILTTLITLIATLSYFSMATSHAVLYHHTVVHTPVSHAPIRLTHDIYRQVFWAHYVDWALSTPLVLLDLALLAGLSGAHTLLAVVADVVMVLCGLFAALGQHGTGQRWGWFAFACVAFLAVVWQLVVNGRRVAVARGGDAGRFYQALAAYTVVVWLAYPIIWGVVSGSRRLSVDGEVIAYGVLDVLAKVVFGAVLLGAHMVTPELGVEVGGFWANGLNKEGMVRLPEEQENGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NS56</accession>
    <name>A0A6A6NS56_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPP4R2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_373896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NS56"/>
    <dbReference type="OrthoDB" id="341898at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="287"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="441"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2454630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="61089" checksum="2A2A511B8B6C8AE8" modified="2020-06-17" version="1">MTAEAEAEDEDEDEGEDEDERLAAVMLLQAAAADGSADVSQWPRVLDALVGRLDEIVHGEFPRPAVVSSAASPPKPPPTPLSPPSSSVAANASQADDHSASQDSQAAADKENAPPSNASTPSRNRPPVPPFPRSSASPAVQRPASSSPEPSTPNAQGTQQPNPIPAATLELHASIVRSLRASFSSQPPHTLQRLAELILRPHEHYRHLPPFLRAVDRVVAVSSPITIFPLPQAVLPGSGTGHLLNGTTSLALNTSDSVGAGIDSDAAALGGALLTPIPWLRQGEANGVSGSSSSSTSPTSSTGQGGGASGAELRSESTTMVEGPHGAGRIETVSVINGAGRTAGIGGGVAGGPATSRAPSGSGSTLAAPETTTSPPPMDQEEPGDAEMTDEGLDATVRTEPTSAGSPTSAEDHPVESVEAALREQGAVTQGELLRQEQEAGVVPVAVASSSRRMRRSGSPLAATGQTATATSAAGKAPAAATPTEGYASADFEPGQVKEGDKSATDMAANKTDRDEDTAPTADASVEEQHEIPHARGPDEIGLEDTGPQMRREPGSGFDLEAAVGRKKEDGTGNKSGESDESSAPEVEMKDAGEAGGGEDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NSA9</accession>
    <name>A0A6A6NSA9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_290909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001690">
        <property type="protein sequence ID" value="KAF2454631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NSA9"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="338" mass="38863" checksum="DFB4D5E7E0B43010" modified="2020-06-17" version="1">MYTPNSVWTWSFLLVACLQGIIALALECYVFGKFQESLQNDAEKTTESRTIPTYLSVYIFGFVYQVVLVYDALRLKNTIQVIGLCLYNVGILIYAAIQMDQIHDAVNFLVGRTMIELDFWNAVRPFLVAIPCVIALGTLLMAVVAWKLYDEFAWTIYKHISADLRLKRRYLVYQIYIALLKFDFFFFLGFTVQFIVIVVKTNDVEFYLTIAAVPVTIIILMLAAYWTRRESVFGMICIIILYFGALAYFLFKLVRMYTDVARREDYLPARRMLTAFAVITVLLLLVTIVIACLCTHNFNKGLKPHISRRKVPDPNDQKDFINEMPTLAGPAGSRMTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NT66</accession>
    <name>A0A6A6NT66_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_352031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001689">
        <property type="protein sequence ID" value="KAF2454965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NT66"/>
    <dbReference type="OrthoDB" id="3063476at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2454965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="133" mass="14128" checksum="FCDA79318D6B4D07" modified="2020-06-17" version="1">MSYDAANRNVSHGRGGAGNIGRTSSDGINREELITPTIKSDIYTTGRGGSGNMAKNDPMHPEIARAAQDVSGEPPREPETNYHFGRGGAANVVRSGSGDRERRGSSHSGEHHKGIVEKGKEMLGLGHGEHDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NTQ1</accession>
    <name>A0A6A6NTQ1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_79379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NTQ1"/>
    <dbReference type="OrthoDB" id="4906364at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="287" mass="33445" checksum="372366A94D4AB4E9" modified="2020-06-17" version="1">MSVHSRLLTEKQSTARTQRAFSRYERTEHPLNELTDRALSGRRFIMDTGIGPVRLNGTGDWAIWIAMLERSAHATDVWQFIDPTVENPPQIPQPSFIIEETSADRFENEMRYDEYKARRTAIEDIRQLVETTVQLCHRQIITRGRTVHEILGELYKRFAPSEEEQRAVLQRQYDTLRQSTPNRRNIDKWIAEWETMYYKCEAVDLFKIDPHAPTKHFLASLAHAGEQWAPIELAILVREPISAWPCLPELIRRFNLFRNVIQPPPGSSRKPQATTFAAQYSHSGYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NU15</accession>
    <name>A0A6A6NU15_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_72347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NU15"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="151" mass="16444" checksum="F0A9BB54E882E339" modified="2020-06-17" version="1">MQRQGRPCLGRATLDAIVWLQFKSLRQSRLASNGSRGARKDGDRSCSRAGSEFAASHTRCLRMYAAGVEGAGGGDALRCVEGSRCCRFGRPETPLGVADTAAATPFLLHILHFRGRSTAPRLTSRPSRTLSEPRCHLAPGARRSRPIKIIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUB8</accession>
    <name>A0A6A6NUB8_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_80410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUB8"/>
    <dbReference type="OrthoDB" id="5429195at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="502" mass="57845" checksum="6450BC6F7BA53665" modified="2020-06-17" version="1">MARRRTSQQMSRAGRPMAQKQETSQHWVAGYEMPPQAVEPRRTIQHLPTPQAPQMQNLQTSSQYWAERYEMPAHVVEPQRTQQQLPTPPTAQTVSSEPASPYYPQACEMSGQGVHDQGMTPLEPLRPQFQPPQPMPQQMWQPLGSLDQTFQPPAVLQQMPTAQTRHSDTMVADNPESLTLDNLSSGNTALLGVNVASSPLYDPAFGKLDRLPIGARNLIFSYMLPESEKALICPWGVCRSAHPEHGGACCFEQLQRAECAMHTNAPLVNFVPCPCQMHLQQDPFDDAFSANHYRYDSSGLAQRRVTLPGLFFANRTIYNQAMGQFWAKNIFRFNTAQLLFLVHDGNKMYQRERMRKIQIEDTDETYPHYFWESPMLLLDNVARGMNLQSVTVGFGFLRNLNHFDIVSVAWFSRWIEAGMQPPDWFLKVYCRRFWAGNFCPFVGFWNSLPPQSREAIEHRLKYLDLRPNLEQRRKVVMLQVPRDMWIRTMRRKAQEVENVLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUK9</accession>
    <name>A0A6A6NUK9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDY21DRAFT_290081</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUK9"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000026">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF14">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="118"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="316"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF2455177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="471" mass="51179" checksum="9CECFDEFA11BAF64" modified="2020-06-17" version="1">MRRSREYDAYAATSEPKYASGASSTVPPHSRHGHRPGHGHGGGAHSHLPLFLRRGSRHGGKGGLLPNRQGESGRSGVHPWMFLKICFRSASSMSMLVNVLWPAVPAAIAIHFARPDLHLAIFVLNYIAMVPAANTLGFSAQELARKLPTVLGVMLETTFGSVVEIVLFMVFISRGEESVQIIKAAILGSILANLLLCLGSCFLAGGFRRDEQTFHEAVSETGSGLMLVAGMALVIPAAFANGLGQGDAAEFEEEVLKISRAAAIVLLIAFFVWVWYQAHSHHGLYEEILIKDEHKDEDRHEDLAKPKLTFTECCLALGISLACVSMIAVFLVEQIHWIVEERGVKDAFVGLILIPVVEKAAEHLTAVDEAYDNQMNFALSHVLGASIQTALLNTPLVVIVGWGLDVHMDLRFEVFDAVVLILAILVVGSFLRDKKSNYLEGALCVLVYVLIAVVAFYYPNPSEEGGEEGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUN2</accession>
    <name>A0A6A6NUN2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_79884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUN2"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="16764" checksum="7CF741A2F7C015AF" modified="2020-06-17" version="1">MHICEARARVCGLSDKSTDGQETTSFCLDMLREALPAFPFIGPMQNMFCHQVADLQRVSGCCQILPSSPGAAAGNRMVYGLEDFLDACERSTYAQPRLVNERLDPNFGPHFEAAWTRFTESQGGGDHSLLRRQQSSTSDSSKAMDISALVNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NUV1</accession>
    <name>A0A6A6NUV1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_77654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001688">
        <property type="protein sequence ID" value="KAF2455043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NUV1"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="217" mass="23963" checksum="09D6A89649AB69A8" modified="2020-06-17" version="1">MEENLQCVCLRPFFSPRRKTRTGLPVAYQKYYVQYIPATIEDQPYTTYQRKSHPPSPLATPSLAYTARFKQVPKHIRPVACNLLGQVTQLATPDASPSTQAGPGRDPGSAKPRSRSARLNANRKACPWMAPGRQRLWRRGVGGGDEALPADYVHTVPMYVCVLAAFAITRAGATYVVRSRFVAGRAMGGSREIDPGGGVYVHRRVCRSSRVRRSAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV33</accession>
    <name>A0A6A6NV33_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_307482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV33"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF80">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2455334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="341" mass="36211" checksum="4206D7122DB72A0C" modified="2020-06-17" version="1">MADTDQLATKSPEVDAAEQQQAPAASAGGDAMAQEGLTMGEHCVTDRPAPPGERPTGEITKLGGVDAYIAKPNDYPHSPSKLLLLLTGGTGIHSVNNQLQADKYASEGFLVIMPDQFDNDPAPNTTTADPATPTETSFISRVKLGAAEAAKSFLIDMWLARHTPEKVLPVLRRALDGARDEFADAVANGQGVYAAGYCFGAKYVLLLAAGVDAHPEMRAWWGVGGKPKDEEEGGAERAEAGGKEPLIRAGAIAHGTLVTHEDIASVKAPISMVCVKDDSLFPNDVREDGRQALVQAGVEHEVEVYPGVPHGFAVLGNYDDQHIKRSQQQAFGQMLGWLQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV50</accession>
    <name>A0A6A6NV50_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_289516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV50"/>
    <dbReference type="OrthoDB" id="441660at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF8">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="143"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2455619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="662" mass="72805" checksum="4019E885989C56CF" modified="2020-06-17" version="1">MSSDEDTVTGADNSPPSTSQQHQHQHQRHAGRSYESDDDDPVGLSDSSRSSSERIKKYVPPRLRKVWGAVVRWVEGPQPPRPYRIEPFFPRIQTAPLRLLDRFFPKRKYKLWLLVAFYACWLAAFASVLHASAFASDIPGYGAPVRLSCAARFWSDRNGCGLNGDGCRPFDNSTFTFRCPANCKRVQVINSHAVGAEEVIYRSLVIGGQMETEQGVTSEAYRSDSFICGAALHAGFMSNTDGGCGVLELVGEQQEYPSTSSNGIRSVSFDSYFPQSFRFVKGTASQCKDLRWPLLAVSLTFTVLLSLFTTSPLVFFASLFAGIFFHVALASDPPNMSNYYAIVSTALGRFLPAAFCAAAIYRFAVRRSLTDLTAQVEKTVLWLGACWVGALNNYTFDKIPIQRLTPHDLHQQPGAITALVIVVLVIFTIALGQAWALRVEGRMPRYLAIYVTMGVCLLLLVAVPRMNVRIHHYILALLLLPGTSMQNRPSLLYQGLLVGLFINGTARWGFDSILQTPAELRGDAKLGTLIPTVLEPQINAPDAARGIPANVTFEWASPLPDGWDGVSVLVNDVERFKGYEDEGPGKESFTWVRSEEHEGLPEYFRFAYLSGSGVGDYSKAGKWGAEYEWTPMEPGPSISGSDSSMNGDEDEGTSESGEDGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NV68</accession>
    <name>A0A6A6NV68_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_396787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NV68"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="151"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="312"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="323"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2455374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="452" mass="46706" checksum="5562CE47BE04C8B0" modified="2020-06-17" version="1">MYVPAAAIPVSTRLRRAIVLNDLTLVKRIVHANPEELQNPDFDDKSNTSLHLAAKYGHVEIAEFLIDAGHEDDGISRNTDWDTPLHIAAATRNDKVGILLINRFPRCVPWPNKQGLDALMLAARHSTLALIPALLSPHLPAPASPAAHDASGNTALHHAAAWGQTAAMRALLHAGAPPLATNHFAWTPLAYARRVADEVYFKNLVAELEKRRVEEGKAGGRPREGSNDKTMGEWAGISERLAGASASASAPASASAGPHTTAADPSSSSSSSPMPPAPPAKDAYLAPRRPPAVPPAGTVRIVTDDAVLGRTAATPNAEGHPRSGTPTTATAAGAPPSFATPTSATPGPAAGRLAPGPRAAEDDWTSPPRLGLLAQEPASPQAQAQAQGLGLGQQGGWSPQQERRRGAAQGGAGRGAAGANEGWSGGFRGGFVGSAGEEGLARMMRERGGGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVD4</accession>
    <name>A0A6A6NVD4_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_348531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVD4"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2455745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="121" mass="13605" checksum="60F7099F84DF5F99" modified="2020-06-17" version="1">MTLFVHSSIISSRSQIIDYVGDFPFLHRGPHVWQNLQFSNAGPHSQEGTQPPSFLGPLSGQTRRARLLAKYPAPRGRSWVLSWVLSASPAKWADRRRGGLCRATLTRSPYANLRLRPSPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVE9</accession>
    <name>A0A6A6NVE9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras guanine nucleotide exchange factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_350215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001687">
        <property type="protein sequence ID" value="KAF2455233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10254377at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="79"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1172"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="269"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="630"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="783"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="870"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="988"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1087"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="789"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="907"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1420" mass="156437" checksum="40690811ECC76545" modified="2020-06-17" version="1">MTRASVLSRRHSDAYAHSSPRFTKRSTADKPASRGSALTSSGTTPTPTPTPTTMPAILQMYDSLTANPDDSSIVRFSPSTGDIVAATPSRLIAHITSPSFLDYELLSDFFLTFRGFTSSTDLATYLIARLKWAVYRADDFGRIVRVRTFVALRHWILNYFVDDFVPSYDLRLYFCELVNELARELRRRSDGGGGDLKIVGELKKCWRRTCALYWENPLALNGRELPDDDIVPGGWFPSGESSSFALVEPLSIPNAPDRETVLQEGTIGQGGALHAPLSGKADSRHLAQPSTSSAPFSSQHNEAAPVSPISERSLQALSCSIPVRPLLRADPGGDRPLYPHPVPVGPSMSPNHAASSKPSRPSHSHSHKRSGSFSDALRDHRAPLPLSKATKPPSINVPFPGSLVRGAVFHPGSPFIDVKPMSSNRPVKAFTDAEANELLKPSLGSTPGVRRILGSVRRVLSSKQPGGSGTVHGGHADQQSNTPAAKDHGGAYSANIELSKRPDRARPRLRIDLLAAKVEASFKEAIREEETKPERQRYLHTGSFSDGRNNYLNVPPRNQSLNPPTGRRFHSNVTAGSRSIVIMDDTGPIDFPFMSGALPIDVKDLKSFYPQRSLPGGTKPTRVPVSARLTRGTEPHSSHLSSLERVLGSTPTTQTRSGDTVTKDSIVSGNNLSERSFWFPRRTKSVSTMRSQTNSLRRLASYHSGMTSSNYGQGFGTKSGGGMYSFHGPEENTPEVKPLRPLRRRPGGDLRAAHNVHDLEHIQRPRSTGSISDHTLSLPNSIVYTPNDMRSHSVERAASDPGAESAGEATNVEKPSISRRRLSLMETRSSQPNMRPSFEAEVAKLAALPDSDEDGGIESALMKLEGRYKKRTQEARNASSGADGDETEGHKDAHTPDRHVRSRSEGTSHGTVTQASANSDHRLQQALSFQMSPSSTDLISPQIAVQSRSMAESEESYSSIPLLERGLSDASAMKRVRYSQQWARSRTPNIAAPGEPIHSQPDQSITSPNSSLEYVEETESMKRIPKGSTMPKSPMNGSFLLEEDRDLSDLSSDLSSEVLDDSETASHGVRSFFDDEPANVDDQHEVFTHPLRHPPTPPLTAKTRTHPSPKSPAGNVHEGQSAPDLITKQRDGAQARPPQKQVTSPGISEHRPPVQKDTSRPSAHLPFVLAYDSETLAQQFTIIEKDALEEIDWKELIELRWKHSSPSIRDWVEYLRTQDPRGVDVVIARFNLMVKWAVSECVMTENIEERVACIVKYIHIAAKCREIRNYATMYQITIALLSADCSRLAKTWELVPAADMKTLKELESLVQPVRNFHNLRVEMETGRIEAGCIPFIGIYTRDLVYNAQKPPYLKSPRADAEPLVNFERHHTSATIVKSLLRLLEASSKYQFKPDPTIISKCLWMAALSDEEITSQSRKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NVF3</accession>
    <name>A0A6A6NVF3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_349643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NVF3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="314" mass="35673" checksum="6393F4DEFB0FA857" modified="2020-06-17" version="1">MVNPDARVECKTDRWHERGLGSCKHCRDNNFLCLRPLDDLEDKQEEFLEAKDNFLALKNRSPKKRRTEKREALQRAAYQYWEAIQTHFDLSHPDQFFELPPLELDPEDLRETAKQYREWERAQLALSEAGGQGSEDEMAVGPQEVATEQETAKETQEQRPQKEECAEAQESSRSAYADDTSQEQKQPPQQLKAPEVSMSMSMPISKLQEYLRILGPFAEQFKIGINITVTGDQNPPAPTSTPALLPPPSKSPSPSIPMAQQTSPSPPPSPETTPSTRRRSLRKRAGIEVEEGKRDGETRAASEIPPKKRRTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW03</accession>
    <name>A0A6A6NW03_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_350045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001686">
        <property type="protein sequence ID" value="KAF2455684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW03"/>
    <dbReference type="OrthoDB" id="3911405at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1480.30">
        <property type="entry name" value="Designed four-helix bundle protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="193" mass="22217" checksum="403356ECC3311E1D" modified="2020-06-17" version="1">MEELEEEVSAKGKKMGVLEKSAKEAEREGARKVDEMRKRAEEAVKKVGGVLEKERAEAKKMKETVERLTSELDELRTERTAAESDEAEKLSEELARERDRVAALRRELKKARAEARRAQEDVAQLRSDVEAVNREVDGRVVEMVRARERQWAARLEKACGERQVMGRALLNEWGKGERGEGMPQEYEYRFVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NW18</accession>
    <name>A0A6A6NW18_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDY21DRAFT_288555</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NW18"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="5">
        <location>
            <begin position="90"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="428"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF2455970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="492" mass="55582" checksum="A01BA4FBA22CF2B9" modified="2020-06-17" version="1">MSSSTSLQRYEGAIARRGHSDNRVVQASFKDLIPLRQRSDVGEISLERPSDEEVAATKERTANALAALVSGAVSAQKPKNVRGASRAEPTYVRYTPAQQMGDASARQDRIIKIVDRQQDPMEPPKFRHKKIPRGPPSPPPPVMHSPPRKLTAEDQEAWRIPPPISNWKNPKGYTVPLDKRLAADGRGAQDVTINDKFAQFTEALQEADKQAREEVQQRRLMQQRLAEKEKAQKEDHLRMLAQRAREERMAAVGGAGGGGRRRRSESFDEDESRGSRRRSYDDDDQSASDDSEAAEEAREREEMRRERRREHERELRQSRMGTERRMQMLAREQNRDISEKVALGMAKPTRSAETMYDSRLFNRSSGFDVGYNEDQVYDKPLFGAQNAINSIYRPTVGGNDEEAEDGGETFDRIQKSNRFEVLGKAKEGFKGAAEQDQREGPVQFEKDTDDPFGINEMISDATGGAAGKKRYGMEEPEAVRSSKRAKVEDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWD3</accession>
    <name>A0A6A6NWD3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_347708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWD3"/>
    <dbReference type="OrthoDB" id="5428863at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="256"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2456019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="717" mass="81361" checksum="5C7B9FB3C1D4721C" modified="2020-06-17" version="1">MFKTLKTSALSAIRSRTRRRDAVAQDKASAEDDTAGHASARFDDVAVEEKRSEITRAGPQDPDGLCLRCAQIDFPQVLCCADIHGRHGNLVLSLGCWAAQIFADFCPFCQMLKCILAPVAEDTYDGAEFELRAFSGKLLWQAVPDAEDDVTAPDTVVLAVSPTMHWRELQEPSQMLRWLTQFEFIGLHSLSAASPPYSLRLVSNEAIDFDIVGWQLRHCRSHHERCRVNVFRPVPFLRLMDTETRELVDSSGDDEYVALSYVWGPPRDYGPNNFPEVIEDAIVATRSLGLRYLWVDRYCIAQNESEKKQLQIAAMNLVYQNAVVTLVAAAGQDDSFGFPGVRGKGRGPQMSADIAGKKLLSSLQNPTNEVQKSKWLTRGWTYQEGILSMRRIFFTASQAYFECRSTAWREAMNGARDTSTGRVENSVPERFGSRVFDDTKMSGESSIAVKDRIGEYSRRNLSYNSDYLNAISGVFSAYEEDPANPLYHVWGVPILSDSLFDRASPDKPDEGLLRGLCWDLVEAPSARRTHFPSWSWTGWDRRVNAFSFYDQRAEMDNECSVQVEMKDGTLVDLITYRQLPQAERTQGKLSHRLHLYASVVQFRLRKQQWGVQEDEYRWIGHPIPLENGSAHLEKESGWVRLLKDDKTNGDFYRELGQATWEGIFVGENKKYLQALCMFILIEWEGGVARRIGTMTIRSDLFLPVCDKVRRRKNIALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWG3</accession>
    <name>A0A6A6NWG3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2'-phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.160</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_288837</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:23324"/>
            <dbReference type="Rhea" id="RHEA-COMP:11106"/>
            <dbReference type="Rhea" id="RHEA-COMP:11107"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:76596"/>
            <dbReference type="ChEBI" id="CHEBI:82883"/>
            <dbReference type="ChEBI" id="CHEBI:85027"/>
            <dbReference type="EC" id="2.7.1.160"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KptA/TPT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.160" evidence="3"/>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWG3"/>
    <dbReference type="OrthoDB" id="419694at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000215">
        <property type="term" value="F:tRNA 2'-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.970">
        <property type="entry name" value="RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042081">
        <property type="entry name" value="RNA_2'-PTrans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042080">
        <property type="entry name" value="RNA_2'-PTrans_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684">
        <property type="entry name" value="PUTATIVE PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684:SF2">
        <property type="entry name" value="TRNA 2'-PHOSPHOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2455844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="275" mass="28724" checksum="89F409DB286CFEC9" modified="2020-06-17" version="1">MSSSHRGRGREGGRGGKGRGSLPRDIVVSKALSKLLRHQAELFGLKLGEGGYVNVKDVLATPPIRTLHVTPDEIASVVATNNKQRFSLAHRTTPSSPLSDPTDLAADPSAYLIRANQGHSIAVDATGLLEPLTLADGDADAGSGAHLPDMVVHGTTNAAWPLIVASGGLKPMGRNHVHFAAGLPAGFAPLEPLPATRELMDAPPVISGMRSTSSVLIFIDLPKALAAGVDFWRSSNGVILSAGNADGVVPLDVFLRVEARKRGGKVLLRDGKLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWQ3</accession>
    <name>A0A6A6NWQ3_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDY21DRAFT_394656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001684">
        <property type="protein sequence ID" value="KAF2456166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWQ3"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000178">
        <property type="entry name" value="Glycoside hydrolase family 16 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF55">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="135"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF2456166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="451" mass="50228" checksum="56E21D964016CC69" modified="2020-06-17" version="1">MYRNFSTPSIATSQIRDPFDDRAAVNSQISTNSSRSSGYSTARPKHVFKSYRLRGEYSQPWRADKRLKRTRINNIIILAFTFLGLCLLAFLAFDGWRSGRSGDYCLVFQDDFASGLSASSWTREVQLGGFGTGSFDWTTSSAQNAFVDGDGLHIVPTLTTESTDISEDQLFDGYSLNLTRAGGDGSCTSTSLAACAARSNSTTGAVIPPVRSARLSTKGKHKIKYGRVEVVAKMPRGDWLWPAIWMMPEDSHYGAWPASGEIDIAELRGNAPGSTADGGRDTVSGTLHWGPDETLDGYRLTHGAKALRRDDFSTGYHTFGLEWSEGHIAVYLDSRLKQVMYVGFDGDRTMWERGHFAGETINQTRVEDPWEQTGRSNTPFDREFYLILNVAVGSRNGWFSDHEDQKPWIDANNNAAGQFIRAKDEWLPTWGKGYDRGMTVKSVKMWKEGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWV5</accession>
    <name>A0A6A6NWV5_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_349286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWV5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025505147" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7764" checksum="50A323D09DDEEDD2" modified="2020-06-17" version="1">MLCGSSLFWEQLLFSSVQTCECAKQSSRSGASPLREILILRYNGVMPLSLDLEVFCNSGGHRAAPRSWMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NWY0</accession>
    <name>A0A6A6NWY0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_65096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001685">
        <property type="protein sequence ID" value="KAF2455967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NWY0"/>
    <dbReference type="OrthoDB" id="3001700at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2455967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="141" mass="15030" checksum="F6F1884A244B90F8" modified="2020-06-17" version="1">MEWTKKQYNQQYDKWVPWLEDQYLYYFGKDNKASYVTKDQLSKTKVTGNKQVDTLQDDVNNLVGNQVGKGGLGEAAGNAVSKEGINRAERGGKDDQGGYAPGPAGSAGNPVAENAKSAGSGVMEGGKKAGGYVSGMWSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXS2</accession>
    <name>A0A6A6NXS2_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sorting nexin-like protein-41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDY21DRAFT_379954</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXS2"/>
    <dbReference type="OrthoDB" id="289314at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06867">
        <property type="entry name" value="PX_SNX41_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044106">
        <property type="entry name" value="PX_Snx41/Atg20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051079">
        <property type="entry name" value="Sorting_Nexin_Autophagy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979:SF2">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="101"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="248"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="458"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="428"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="460"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF2456358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="680" mass="73236" checksum="FB2F7180978CE246" modified="2020-06-17" version="1">MWDDEDNNPYGSLDRRDSENSHPGHLGSPGAGFQRPETPPSGISTPRDESPEFVAQPGALSDVDYDEEIARAGSAGGAGSGERRRPPKKGGYDSRIEQILYEFPDQPILITHAGKNLESGGSYIAYTIRTGDLEVRRRYSEFASLRQTLVNLHPTLIIPPIPEKHSMADYAAKPTKAKEDVGIIELRKRMLAVFLNRCRKMDDVREDGVWWRFLDPNASWNEVLHSHPVSSIPKNVLKAPPLDTANPTPAHAYLPVPSSSAKLKPSTTVPSGTPASPPSHAASATAAAHTIPGPQIFGKFPPSAKNLSEEELDPYFMSFEASSRELETLLQGSMEKVNRRLLAHLASLGDDLAELGARYNGFALSEQAPSLAAAIERVGQSADSTYLQTAELSAGLSAGFAEPMRESAQFAGVVRAVLRYRVLKRIQEEQTRDELAKKRALLENLERSEMEARRIEQYLSSTTGSGAAGSPAETRPRRSGSSASQKSDASSGAADQGAGAAATGPPHRPDEDVASIDSDFPPTHGEPTSPGGGGRTSEATSPTTSPTKNHRKSSSAGFGGGGGGGGGGNFVTNKIFGRISHAVHGIVDVDPERTRRDQIGKTRESLVNLEQALDVASKDVKDASAAVLADLKRFQMDKEDDLKRYMIAFAKCHIDWARRNQQTWEEAKAEVGAIEPRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NXT0</accession>
    <name>A0A6A6NXT0_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_386514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001683">
        <property type="protein sequence ID" value="KAF2456566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NXT0"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="79"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2456566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="586" mass="63064" checksum="A73D14F611DCBA33" modified="2020-06-17" version="1">MLAVDRTAQAPNGASSKYPNDGLRLARISAQPDNPFSSLIPDQTIAIIPSFTLESGVTLYNVPVAYKTYGVLSPERDNAMVICHALTGSSDVADWWGPLLGGPGKAFDISRFFVVCINSLGSPYGSASPVTSKDGDPAKGRYGPEFPLTTIRDDVIIFKLILDDLGVKRVATVIGGSMGGMLVLEFAYFGRDYVRTIIPIATSARYSAWGISWGEAQRQSIYSDPKYDDGYYSFEDPPSTGLGAARMSALLTYRSRDSFEARFGRNTPDPSRRQNINGHQQRVGGVGDARPTSPAHEHYAIHNDGHKHAGSPRVSRTNSGSAPKLTTATEKDDPEFHTLTQGASSATRNGTSSPFGGGGGGGGASSISRTTVAGGGSSLVGAEGPKKRTPTYFSAQSYLRYQGDKFIKRFDANCYIAITRKLDTHDVSRGRFPPPRRGGDDDDDATAAAAHPDEASSSPLQHALSLISQPTLILGIESDGLFTFAEQRELAACIPQAALRTIDSSEGHDAFLLEFEQVNRHLLEFLERELPDVMAREPVGVEGLEVESAGEAEDEGKVRKRKVKAEMQVKKTSTFGEAEVDDITAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NY36</accession>
    <name>A0A6A6NY36_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_39767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NY36"/>
    <dbReference type="OrthoDB" id="5237031at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2456631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="247" mass="28371" checksum="7399E782532D9F44" modified="2020-06-17" version="1">MAEFEPAFLPMYNDDSIRLQEPCVAPNARQWRFEVEADCEAWFHAEISNIVLSAWANYPTILQSSHNKPLSEVNTTETVDVMYSMKYGNAKLPLVIGEFKRNLIHPVQWQSGETPSSSQKKLSRELRGYAHKYQCPHVFCFDGETLLLQFRASKMENLEDEECPVDFWVLPRTNSSCTLRYALYRLLVQGLRRCQGYLGGELTIGNLTTNSRQFYSGRPTWKINGKKELQHPQGFERSIDASTGSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYV3</accession>
    <name>A0A6A6NYV3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-mRNA-splicing factor CWC24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_286919</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the CWC24 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NYV3"/>
    <dbReference type="OrthoDB" id="25761at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034247">
        <property type="term" value="P:snoRNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16539">
        <property type="entry name" value="RING-HC_RNF113A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039971">
        <property type="entry name" value="CWC24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 113B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930">
        <property type="entry name" value="ZINC FINGER PROTEIN 183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="4 5 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="191"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2456758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="273" mass="29527" checksum="02E8D4CAFF48750E" modified="2020-06-17" version="1">MSAPVVFKKRAAKPSAAAKPRPASPPSGSSGDSSPDEASGPRVKRRRANVVTASSTQPKRPEAYDATAAPSIAADKSATIEASDDATRQARSYGPQKAAGNVRTITFTDYAPDVCKDYKQTGFCGFGDTCKFLHAREDYKAGWALDKEWETATKGKKLSGTVVASAKRDAKLHDSSDEEDAALLEKIPFACIICKEPYKQPVVTKCGHYFCERCALKRYANKKPDCAACGAGTGGVFNGAKNLKRILDRKAAREKRRREKAKEQGLEVSDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NYZ0</accession>
    <name>A0A6A6NYZ0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin cytoskeleton-regulatory complex protein PAN1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Actin cytoskeleton-regulatory complex protein pan1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDY21DRAFT_41648</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000349">
        <property type="entry name" value="Actin cytoskeleton-regulatory complex protein PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF173">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02205">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="20">
        <location>
            <begin position="75"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="20">
        <location>
            <begin position="358"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="21">
        <location>
            <begin position="391"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="169"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="490"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="692"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="876"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="616"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="711"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="746"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="794"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="809"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="896"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="932"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="961"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="1086"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="1123"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1140"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="1186"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="1240"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1303"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="1313"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="1332"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="1350"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="22">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF2456727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="1407" mass="150019" checksum="61B98837E39E91CD" modified="2020-06-17" version="1" fragment="single">AAAAAAAAAAAAASQQQQQQQQPQPQRPQPTGMTSSQMANSFKASGSSQAPTPTGPPSGGTKIPNIRLSFITAQDQAKFEQLFKSAVGNDQALSGDKARDLLLRSKLPGEALSQIWTLSDTTKSGQLLFPEFALAMYLCNLKIVGKELPHTLPEKIQNEVSSMVDIISFGVPDEKPPTPARNANTNAPSFDTPVRQSTMSPPTIQQPQPQPSNSQLLSQLTAQPTGFPGPHGGGFQGGPPPQPTGLQAQATGFPGAMPQATGYSGPRPPMPPMPTGFPGSSGSPAQAGGPLAPLNAQPTGIPGQWGLANNPASGLPNIEALQQRMMPQAGGGSGGAGGFTTSGLRGNATVPWAVTKGEKRIYDDIFRAWDGLGKGFISGDQAIEIFGQSGVDKGDLERIWTLSDPHNRGRLNLDEFAVAMHLIYRKLNGYPVPNRLPPELVPPSTRNFDESIGTMKSLLSRDAEERKSSGAFLQPQHTGVSYLKNHSFRGGSPVASGRKDATVFKNNDDDIGYRSSARHRVGGARSPKPPSSPSSERSDGPELSVEQLRKLIREKQVLLDAMDFEDENRFEEDEALDRRDRREAEDLYRRIRRVQEDIDAHPNSGLGAGPDSDAERRALRRQLQHLTDKLPELASNVRRVERAIADAKLEVFRVKDAKAHPNAAAAIVGTGPGGAITESDRLKARAKAMMQQRSAALTGRPAPGGADDADAAAKRLEEENSRVRMERENNERMIRDVEESVNDYSRGLEDGLKEGGGDASSEHERRRWEDGLGVEDEVKDFIYDLQRSSRAARVRREDDVHRSRDRHSPPSSRYDTPSRPTPPSRADSSSAPPVSPPRANTASPSAGGGASYQTYKTAEERAAFIKQQAEQRMAERLAALGLRAPSKAVGESPQQRMERERKEREDKLRQAEEEDARRDQERQRRLEAEGLAPPSSSASKAAPPAPGGKKAQPPPPPSRKNKAEQERHDAAQAEAEAEAKRAEQELAEKALKEQQDAQEKERREMEDEEARQEQELAREREAAQARLRALEEQVKQGKVKKEEEKRRKQQAQREAKEKEARLAAQRAEIEAARERERQLQMQLEQMGDESSSDDEGPPEITPQETTPTASQELPRDSPAALPTAPPTAPPMPPQPTRQESTPPSSVTSPPASAMTSPPPGPAAHADTETRNPFLKKMAQTSEAAPSPAPPAPAPAAPPADAPASTNPFHRFAQEPKPAEATPPPPAGGTGPTRSSRVRSDDDDWSVVDSSDDSSDDDDDEARRPGGGGDAKQLASILFGTMGPPRPLSATDQKSPRPESPNVAASPASTSGPGAPPPPPPPPMPGAGTGAPGAPPPAPPPPPMPGAGGPPGAPPPPPPPMPSAGAGGGAPSGGSIPSGLLGQIQAGKGLRKVETKDRSAATVAGRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZC3</accession>
    <name>A0A6A6NZC3_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_344758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZC3"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025553109" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10864" checksum="E7C39F7318ED4FEB" modified="2020-06-17" version="1">MTCMLPGAVLLLRLAHVCSKRGTGKPSQQQQQQQQQQYIPGIPAATIARTIVFSGPVIRILERFPTRPCNPFPHLLAPPPLLWPPDGAKGDSRCRDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6NZJ4</accession>
    <name>A0A6A6NZJ4_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">allantoicase</fullName>
            <ecNumber evidence="3">3.5.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_346578</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Utilization of purines as secondary nitrogen sources, when primary sources are limiting.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>allantoate + H2O = (S)-ureidoglycolate + urea</text>
            <dbReference type="Rhea" id="RHEA:11016"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="3.5.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Nitrogen metabolism; (S)-allantoin degradation; (S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the allantoicase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.4" evidence="3"/>
    <dbReference type="EMBL" id="MU001682">
        <property type="protein sequence ID" value="KAF2456947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6NZJ4"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004037">
        <property type="term" value="F:allantoicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000078">
        <property type="entry name" value="DAL2p Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000059">
        <property type="entry name" value="Probable allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00813">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02961">
        <property type="entry name" value="allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="ALLANTOICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045:SF3">
        <property type="entry name" value="INACTIVE ALLANTOICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016516">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="8">
        <location>
            <begin position="43"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="8">
        <location>
            <begin position="221"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF2456947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="366" mass="39670" checksum="D848888470F86715" modified="2020-06-17" version="1">MEVPAVPPEAVQEGLTGVRQIPAEDIDATFKSNTIDLVSKPLGSRIVSLSDEWFASASNLTTPTPPVRKPGVFTHAGAWYDGWETRRHNRAPFDFVIFRLGVASGRVHGVEVDTAFFNGNHAPEVSVEGCALGADDDDDEARLGAPDFPAWEPVLPRQECGPSRRHAWLLPPRPAAPAYTHVRLAMYPDGGIARFRLYGLAEPVFPAAADAVLDLAAAVNGGVAAACSDQHFGAKDNLLLPGRGVDMGDGWETKRTRGPHVDWVVVKLGAPGEVVKVVVDTAHFRGNFPQKVAVFAGRWAEGVLPGSEDKGWVEVLEPMETGPDREHEYGADVLKNVKGETYSHLKLVIIPDGGVKRFRVFGRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P021</accession>
    <name>A0A6A6P021_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WHIM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_286128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001681">
        <property type="protein sequence ID" value="KAF2457137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P021"/>
    <dbReference type="OrthoDB" id="349045at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107:SF1">
        <property type="entry name" value="WHIM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107">
        <property type="entry name" value="YALI0D24453P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHIM1" evidence="4">
        <location>
            <begin position="108"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="409"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2457137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="580" mass="63699" checksum="5F4B5A51F2E6F6EE" modified="2020-06-17" version="1">MAASPAPSPRKKRPASPPHEEVLADNPDIAFLVMFRARFSDCFPPKVPNLGPQDIERGVVDSAPSPQVEHLLCALLALVLNRKKPVERGHYGRALEDAIQSHKSEWPRAWNNVNPLSGGKSFNTMSPQERLSLLRALVLWSLHTSDVISATMKESYKQSRQEDDRNQPLSVQPWGIDGEKRRYWLIEGRDDTNFRLYRETNPKQTPCRWWSMAGTLDELRAIAERLGNEESQAARRLATQILNAIPRFEATEEKRKRREYRQARKAQFSRPEPGFSLYEGRTRGKRMRYTFSDDEDELLQQSDSTSAARRSARHSARATPAEPARPTVTASGRQVRSRVGGAYGEALLSGPTTDRGTPATADYARSDASNEDGGSGGRPTRGSRSAAQRPNGRWAAGGKNHIEGYNSVDEMEDEDEAASTGDDEWDGDAELDMGDDDGDDGASETGESDLDEEKKLVVKLKYRAPAAAKKQEVKPTLVEPKEEPMKMEVDSAAPSTLQRPSSPPKPTQPVVTTTNGYNLPTPASVAAKVESTNGISHVPSPKKELSTMTNGLIAGPQDGTRSSPAPSASTSDALKLPTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P0L2</accession>
    <name>A0A6A6P0L2_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phosphoglucomutase-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDY21DRAFT_285524</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P0L2"/>
    <dbReference type="OrthoDB" id="8300170at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05799">
        <property type="entry name" value="PGM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000035">
        <property type="entry name" value="Pgm3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745:SF1">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745">
        <property type="entry name" value="PHOSPHOMANNOMUTASE 45A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="44"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="230"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="15">
        <location>
            <begin position="330"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="12">
        <location>
            <begin position="537"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF2457496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65114" checksum="DA16C56B9B1814AE" modified="2020-06-17" version="1">MTNARELAEEWLRLDQDPTTREDVKQLLVEGKEDELKERMNPRIAFGTAGLRGPMQAGFARLNSLTVIQASQGLAEYLLEQESDVRHRGVVIGRDARHNSLKFAKLAAAAFVAKNIRVWLYSDPVHTPLVPFGVGELGAAAGVMVTASHNPAKDNGYKVYWSNGCQIIPPHDKGIADAILRNLEPVTWDTSVVDEDHLLIESAIGLVEEAYFRAVRRGTVPEDATAFPPAPEGLRFVYTPMHGVGLPFMERAAKDLGFSVSDIVIVKEQAQPDPNFPTVVFPNPEEKGALDLAMKTADGERISLILASDPDADRLAVAEKVDGKWIQFSGNQLGILLASYILSSWRDSTINCSSRDQELAMLASTVSSTMLATFAEREGFYYAETLTGFKWLGNVSKHLDSKGYKTVFAFEEALGYMIPSVVSDKDSIAAAAVFLTAAGEWQRQGLTPYRKLQELFKTYGYFEDVNTYLISPSPGATNAVFQSIRSSAGDKPYPAQLGSRKVLRWRDLTEGYDSATDDHEPVLPVSKESQMITCEVEGGVRFTIRGSGTEPKVKLYVEGKGASEDEARAAAKDVLDLLLREWIKPEFGLKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1A5</accession>
    <name>A0A6A6P1A5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1A5"/>
    <dbReference type="OrthoDB" id="5405781at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF128">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="8"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2457522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="431" mass="48539" checksum="5A2974E84982ECFD" modified="2020-06-17" version="1">MPAARDANWVDGLRGTASLMIVCGHLCTAFVPWLHRPAMAEDEGPWIFQLPLLRLCVSGRAAVAIFFLITGYVNSLGPISKSRSGNTDGAFASIARSALARSGKLVLPTIFATFVSWFLAQTNAYKMAQHIDATWIRQGYHRQEPTVWLAIVHLFRAQIATWIGDWNEYDGTQWTLHLFLEGAMMVYLTMLASVLVTPRARKYIYGALYVYAWLAGNNHEATIKSLNIIAGMFVAELNVELGSSATETLPTPVPSFLILLGFFMSGYPQECAEWMPWSNTMRVIMEPIIPEHADLRRYWDHLGAATILMGVFFSRNARRLLTSPVFNFLGRVSFPVYLLHNQLMKSVLVWMIYTPSWLNPPKNDKGELMDLQRASLPHCLVAIAVFYYILYRLALAWTVYIDPICAKIVKWATSKAYGDGQEGNWEKAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P1N5</accession>
    <name>A0A6A6P1N5_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_371304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P1N5"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2457728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="79" mass="7927" checksum="C85D157B5D925B40" modified="2020-06-17" version="1">MAPETRLGRRRFRPLLAAPGSKGLGAQNSPPYLAAGLASWTVPLDLGSAAPPPGLLGGGQGMFDVDLEEASGKSPGGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P231</accession>
    <name>A0A6A6P231_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDY21DRAFT_284971</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P231"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14135">
        <property type="entry name" value="STKc_PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase PRP4 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044092">
        <property type="entry name" value="STKc_PRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF103">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="244"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF2458065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="574" mass="65012" checksum="6C58A60F82DE0EFB" modified="2020-06-17" version="1">MDTTTPADVVETESAPVDEAAVIEERRRKREAIKAKYKNQSQDLRIQALQLGNDSGSGTPKTEIPDIPSARSRKLSPMATSPKTPQDVTNPSSPGDFAIHSGVELANDAAHHPAVDDNEGPSAADYDPTGDMQDDRARNVQRFGNEEQPSASYDETKEIHRDVLVPETTPQDSQETKPQKEFDMFAMDDEDDMFAANWNDKPKETARPIPLHQDGQVDLSLQDNWTDPDGYYRVMLGELMNSKYRVRANLGRGMFSSVVRATDTQTNNLVAIKIIRSNETMQASPYLLARKAGMKEIGILNQLADADPDNKKHIIRLERYFDHRGHLCMVFENLNINLREVLKKFGRDVGLNLKAVRSYAHQMFLGLTLFRKCNILHADLKPDNVLVNDAHNLLKICDLGSAADASEADITPYLVSRFYRAPEIILGMPYDFAIDMWSIGCTLYELYTGKILFTGRNNNQMLRSIMECRGKFSNKMLRKCQFALDHFDDSLNNFRSMEKDRITNRDIIRVIQIVKPTKDLKSRLITADQGLSEAELKEVNLFIDLLDRCLQLNPERRITPIDALKHPFISRAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2E0</accession>
    <name>A0A6A6P2E0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="2 12">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDY21DRAFT_303799</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10 12">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="2 12"/>
    <dbReference type="EMBL" id="MU001680">
        <property type="protein sequence ID" value="KAF2457613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2E0"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000025">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF151">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="3 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 12" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="48"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="393"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="188"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="225"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="365"/>
            <end position="368"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="86"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF2457613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="512" mass="54580" checksum="B77D469B8EC5EFEC" modified="2020-06-17" version="1">MLRTLLPRRAPARPLVTQFGAANTFGPSLGVSAGQRWRRGYASEADEKDLVIIGGGVAGYVAAIKAGQAGLKVACIEKRGSLGGTCLNVGCIPSKSLLNNSHLYHQILHDTKKRGIEVGDVQLNLQQFMKAKDQSVEGLTKGVEYLLKKNGAEYIKGAGAFADEHTVQINLNEGGERSVRGKNIFIATGSESTPFPGLTIDEKRVITSTGAIALEQVPKKMTVIGGGIIGLEMASVWSRLGSEVTVVEFLGQIGGPGMDAEIAKMTQKILAKQGLKFKLNTKVASGDVGSDAIDLKIEAAKGGKEESLDADVVLVAIGRRPYTAGLGLENVGLETDERGRLVIDHQYRTKIPHIRAIGDVTFGPMLAHKAEEEAVAAVEYVTKAYGHVNYGAIPSVMYTYPEVAWVGQNEAELKAAGVKYKVGTFPFSANSRAKTNLDTEGMVKFIADAQTDRILGIHIVGPNAGEMIAEGTLALEYGASTEDVGRTCHAHPTLAEAFKEAAMVCYDKAIHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2G1</accession>
    <name>A0A6A6P2G1_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_341898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2G1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="100" mass="11553" checksum="9CA8D6FD696A7E7B" modified="2020-06-17" version="1" fragment="single">MSGCTAYRKGGWEREFRHRGIRTRKITDALVAADWDIPPEPKSGGPAPPDHPEAQKPKGFVQIMQDIQWNNLSTSQKIYETGKGWKDRASWTVKNWWRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2H7</accession>
    <name>A0A6A6P2H7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDY21DRAFT_343288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2457978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2H7"/>
    <dbReference type="OrthoDB" id="419770at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025708514" description="Post-GPI attachment to proteins factor 3" evidence="7">
        <location>
            <begin position="27"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF2457978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="333" mass="38333" checksum="EC85E0ADF1B38F38" modified="2020-06-17" version="1">MKPNEKLLPWLLVSIALLARLSAASAGDYLPDFRSCVQVCIETNCGHDGPSIPLQRRLLLWDCPSECDYTCQHVITNKRLARDPPYMQPVLQFHGKWPFHRFMGMQEPFSVLFSLLNYLAHDYGMRRVRAEIPASYPLRPFYLAFGYFGLVSWVFSMLFHARDFNLTEKFDYFAAGASVLYGLYLAVVRIFRLDNVDPTAGGAPRRRSVLRAWTVVCGTLYLAHVTYLTAWSWDYTYNMAANVAVGVLQNILWSWFSVERYRRLKRTWAAWPGLIVAWVVLAMSLELLDFPPWGGMIDAHSLWHLGTVGPTVWWYSFLIKDAKEDLQGTRLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2Q6</accession>
    <name>A0A6A6P2Q6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypoxanthine guanine phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDY21DRAFT_343482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2Q6"/>
    <dbReference type="OrthoDB" id="9973266at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000033">
        <property type="entry name" value="Xanthine phosphoribosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="4">
        <location>
            <begin position="11"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF2458048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="204" mass="22945" checksum="218F7F90CC66BFC6" modified="2020-06-17" version="1">MVEKIYVTYNQVHKLCQESAERILNEVKPNLMIAIGGGGYVPARILRSFLKKPGSPNIPIQAIGLSLYESLGTDPVEQPGTKVTRTQWLDLSSLEMANLIGKNVLIVDEVDDTRTTLEYAVRELEKDVLEAQKRLDRQGEKTTFSIFVLHNKDKPKKGKLPEDFDTSPSRYLAAKTVGDVWINYPWEATDIDEHDKLATTQGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2S7</accession>
    <name>A0A6A6P2S7_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_343443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001679">
        <property type="protein sequence ID" value="KAF2458032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2S7"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="110" mass="12143" checksum="E75D7681798C323D" modified="2020-06-17" version="1">MALDDIWAVQLPPENVTAAKIKDRMREGLRQETRQEKWAEVKYRYVNGPDEDVSTVRRSEGSEAEKGCGRRAMFAAARGTEVDGASVVVWGGVDARGKVADDGWMVTVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P2X7</accession>
    <name>A0A6A6P2X7_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDY21DRAFT_284422</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P2X7"/>
    <dbReference type="OrthoDB" id="3944240at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="314"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="612"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="632"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF2458082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="734" mass="76898" checksum="DF6D0AA0E3361C75" modified="2020-06-17" version="1">MSGGGMSMGSMSMGGLPSNFTFQRMYWAVVGTAVGIAFVVNVAQYALFRQRIHAARRGDPTPAKPKSIPAVFFATLTALAREASHAAPPPLRLGGRRLAIAFPTVGATALVLGNAVVLVVLSLYGLDTASLRAREDVAFRAGFVSVAQLPLVFLLAGRNSVPGWLAGSSHERLNGLHRWSARCLLLTATLHMGYWVGAWAPYDYVGRKVAGDPITQRGFAAWAVLVWIALSGAGWLPLRRRWYEVFVVQHVASFVALVALVYLHTPAEVHGYIWACVAIFFFDRVLRAARFLGANLAVLHPRRRRRRSGGGGGAGALWACEAELAPLAGGATRLTVRDPPIGTWRPGQHVFLACHGVAPLQSHPFTVASLPEDGAMEFVVKAERGGTRRFFRHASGGGKQGTRSVAIEGPYGGAIRPLRQFDSVVLFAGSSGATFTVPLLRDLVSRWRKAAAARRPSPSSPPPASGSTSRLRRVLSAIDARGDDADGATVTRYVRFVWVVKSRGQLGWFAAQLSATVAEAERISRASGSDSSSSGGGGGGGVGGFQVRVHASVYVTCDETLAAEHGSLLAGLPAAAKRRRTVGEGDVRGDVDAIANAAAPVCTCSGGDATVSSGAKAAPWPSQPSAHDDDAAAAAAKQPPAATTTTTTTMADAALPPGLLVHPSIALLGGRPRVRDVVRRVLERARGESAVVVCGPAGLAADVRAAVVGLSDERAVHKGTGAQGVYLHVEGFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P337</accession>
    <name>A0A6A6P337_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Membrane anchor Opy2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_214103</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P337"/>
    <dbReference type="OrthoDB" id="5244543at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2458148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="36218" checksum="9FB93638D4D04BD5" modified="2020-06-17" version="1">MSSPAATQTYAADEPACTWTGHCLGDPCTTYDDCDHDWVCSPEQQVCVPCCLTVTDTALPTSASTTAPSSSATSAASGDGDSSGLSTGAWVGIAIAAAAVVLFIVGFLFFCFRIRPRRRERKLRALAAGSTDEKAGHGAVELPNSPPAPPPPQEMPVEEQRSEVANTPAPVYEMPDTGVLSSEKKASVYETEAGRVPSPRERPRWTEVRPTPAGTDYADDTGAGSGSTDADWALQHSSRPAPPRPEGDRPYNNNSPAISLTGLSAPDASPNAVSGVSPPSSETGTNSWGGIRGSPAPARGPSPLTPGYGGRQDYGWAEPQQGGQVGYYDSRDTGDSGRRSDRVEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3G9</accession>
    <name>A0A6A6P3G9_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDY21DRAFT_410475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3G9"/>
    <dbReference type="OrthoDB" id="4347at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055323">
        <property type="entry name" value="C57A10.07/YOR238W"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28110">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28110:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF2458516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30261" checksum="7F169DA6FC3C73AD" modified="2020-06-17" version="1">MSTPPPPLPSPHPTHLILVCCHATYLGPSSPSSPSPSPYAESSWLLHPYQRSAGSRPGEHLTFVAHARAGLDLLRHGCGGEGDGLLVLSGGATAARARSEARGYRAVLRWVAGREDGGDGGAAARVVLEERATDSFQNLVFGIVEFRRVAGGYPERITVVSHGFKWERFMNVHAAAIGWPRDAIRFVGINPPFSYAEWQQTVKGELDHGLELWRKDIFGVGPELSKKRKDRGWDEKMLDEVADGLEESVQKLIKCNEVIELGSSATYDLDLPWKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3I1</accession>
    <name>A0A6A6P3I1_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDY21DRAFT_385386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3I1"/>
    <dbReference type="OrthoDB" id="9984693at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF1">
        <property type="entry name" value="PROTEIN TED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF2458308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="61666" checksum="BD1DE0249EA1DFBC" modified="2020-06-17" version="1">MRFGFPGFLPRVVRLLFPPCITATLYLYLYPLFHGCSFPRPARRAPDWCIEALNGSDSNGGPLCTASHALPTTAPFRLLSLGDPQLEGDTSLPNPTGPAFPSVPEAWDGILRSGSIRDALDAASHGARELVRSDVPRALYAARKRLDLLGNDYYLAHIYRTLHWWARPTHVTVLGDLLGSQWITDEEFERRGWRFWNRVFKGTRKVPDSAMAKGEDGKLRKEVLGQEKGWEDWLINIAGNHDVGYSGDLTKERVDRFERVFGPVNWNIKFELASNTSSVEAFAPDTQPESPELHLLVLNSMNLDGPTISPDHQSATYAFLNDAITRSRPVEDRTHLTILLTHIPLHKRAGVCVDAPFFSYHAGYNGGGVREQNHLSEGSSKGVLEGVFGLSGNPAAPAKGMGRNGVILTGHDHEGCDVWHHVRQEVYSENGVAPEWEALKWEEANKAGLVGWDGIPGVREVTVRSMMGSYGGHAGLLSAWFDECLGEKGEWRVEFEYCAVGVQHIWWAIHIVDVVLLGLLAVSLLIFLWKQLRSVFKGNSEERAKIPEVKRKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P3Z0</accession>
    <name>A0A6A6P3Z0_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_340370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P3Z0"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17815" checksum="4E59F7A7F630D330" modified="2020-06-17" version="1">MSVGRVFTARGNASSSSSYSHVRLQFIKYLLPFVSCFLLTLLFLSTSASFLTSIHVLHSYISSNVRLRAAPRWLASSRVLLSCKTASFDLSGRASFSLFSFLSWCLASFWLTGRLSGSVPLFALFFSSTSTCARGHSGRDLSCCLEGGGAGFVLGGWMCGAKVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P423</accession>
    <name>A0A6A6P423_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase, mitochondrial</fullName>
            <ecNumber evidence="6">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDY21DRAFT_205920</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAM41 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6"/>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P423"/>
    <dbReference type="OrthoDB" id="341477at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015222">
        <property type="entry name" value="Tam41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619:SF0">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09139">
        <property type="entry name" value="Tam41_Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028840">
        <property type="entry name" value="Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="17" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="30"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="426"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF2458564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="502" mass="57640" checksum="0D775AEE2856C978" modified="2020-06-17" version="1">MYTFSRVLSVRSPPLHSCVRHAVFFHSSRAARWPQSTPESSRDSVRRSETSSTSPKNKRPSMDRSTNSSPTSTPASESNQSLPPGWEDELNRHLTTFAQLPHRTFGFNQHMIINEEFKESLRQILWQFRAPIRYAFAYGSGVFPQNDGSMPPASLSPHPHPPEAVTKWQKGGGKIIDFIFGVSYTQHWHSLNLQQHRDHYSFLGSLGSAVVTRVQDKWGAGVYFNPYITVNGVMIKYGVVNLDVLSRDLQQWETLYLAGRLHKPVKILRDDPQIRYSNQLNLIGAVRTALLLLGEKFTERELYTAIAGISYMGDPRMSFATENPHKVKNIVGNQLTNFRQLYNPFVGTLPNVTYCDPRCSREDWIHDAATDARMTQDMDPVKRGNMVRRLPKAFRDRLYLQYQKKFQIPGRDFARMLEESKDEDESSFKRRQGGEFDRRIAQEPDIRQQVAEAIRLTVKWPSYSQTVKGLFTAGPTRSWKYLGEKWEKKREGDKMGPSDTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P465</accession>
    <name>A0A6A6P465_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase class IV-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_301623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P465"/>
    <dbReference type="OrthoDB" id="5288718at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="36806" checksum="1FE59C5ED4EFDC28" modified="2020-06-17" version="1">MATSAEDFELFTSLRYDPLLLKSVENGSGGLSFVSPSPFYMLVYHRDRMLEAARHFGFDAAAEKLSDGKALSEALLSKVRKYQKESEAKDGPLRIRTLYNRAGDLQVDMSPVPPVPLEALYPPTLDPPPNPKPPRVSPLTGGALTLGPTDSLSSSSSPLPPTIPRWTLMLDSHPTALTAHTSLKTTHRPHYDASRARSLPGNSDGASPAASAAALTEVFLYSPVGEITEGSISTPYFFRGGRWVTPPVGTPPAAGPFTTPTRQGIDGGPDVPFAGRWGHSVRGGGQRGTTRRWALRKGLCQEEGVERASVKIGEGVWVSNGVRGFGYGIVVEGKTEDNDAAQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P466</accession>
    <name>A0A6A6P466_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDY21DRAFT_283949</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001677">
        <property type="protein sequence ID" value="KAF2458568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P466"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23795">
        <property type="entry name" value="UBCc_UBE2G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000048">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF2458568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="153" mass="17656" checksum="EE0B874291E64386" modified="2020-06-17" version="1">MQTDKDIPGISCGLVDSNVFEWDVMLMINDDCKYYGGGFFRARLSFPQDYPLMPPKMRFITPIYHPNIYSNGEVCISILHPPEDDKYGYETAAERWSPVQTPETILLSVISMLSDPNFESPANVEAASMWRDNEKEFKKKVRKCVRDSLEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4L6</accession>
    <name>A0A6A6P4L6_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DASH complex subunit Hsk3 like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDY21DRAFT_275144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 16933</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MU001678">
        <property type="protein sequence ID" value="KAF2458383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4L6"/>
    <dbReference type="OrthoDB" id="3358869at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042332">
        <property type="entry name" value="Hsk3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013183">
        <property type="entry name" value="Hsk3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28289">
        <property type="entry name" value="DASH COMPLEX SUBUNIT HSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28289:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT HSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08227">
        <property type="entry name" value="DASH_Hsk3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF2458383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="83" mass="8793" checksum="CB30EF36774A54C6" modified="2020-06-17" version="1" fragment="single">MSQLPRPPTNASSRLSTLPSQKPRQLSHLHAQLAQLTANVTDLENLLRMTAVQAESMRGLGGYAGAMFMAASKILGEETVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P4T8</accession>
    <name>A0A6A6P4T8_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rho GDP-dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_283268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P4T8"/>
    <dbReference type="OrthoDB" id="1683373at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.30:FF:000001">
        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="198" mass="22462" checksum="9C760FBA270C230C" modified="2020-06-17" version="1">MPEQTHEDELTPDQTAGFKVGEKKTIEEYQQLDQNDESLRKWKESLGIGSGKDISDPNDPRKVIILSLGLEVDGRPDIIVDLTSPGALESLKDKPFTIKEGATFRMKAQFKVQHQVLAGMKYVQVVKRMGVSNKSQEMIGSYGPNTTEKPVYEKKFETETAPHGMIARGHYNAVSKFVDDDNETHLKFDWSFDIKKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P5I6</accession>
    <name>A0A6A6P5I6_9PEZI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uridine kinase</fullName>
            <ecNumber evidence="5">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDY21DRAFT_339593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="5"/>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P5I6"/>
    <dbReference type="OrthoDB" id="738517at2759"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002070">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF2459038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000799766"/>
        </source>
    </evidence>
    <sequence length="323" mass="36447" checksum="76B99FEF5DFDE069" modified="2020-06-17" version="1">MHPPFAPPIRTWPLPRRSPLSMQRDKYSPPWHDTSLIGIAGSSGSGKTSLALAIVASLNLPWVVILSMDSFYNPLTPDQSVKAFNNEFDFDAPEAIDFDLLLQKLKDIKSGKKTEIPIYSFEKHQRLDKTTTIYSPHVLILEGIFALHDERILDLLDLKIFCEADADTCLSRRLLRDVECRGRDIQGCIKQWFGFVKPNFHKYVEPQRNTADIIVPRGIENKVAISMVSDRIRKTLSHKSAAHQAELERLATSAAAEASTALPSNVVFVEQTPQVRGITTLLLDEATSREDFVFYWDRMAGILIERCVSSSLSRPQLFLPPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-06-17" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6A6P6F9</accession>
    <name>A0A6A6P6F9_9PEZI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDY21DRAFT_339550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lineolata rhizophorae</name>
        <dbReference type="NCBI Taxonomy" id="578093"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetes incertae sedis</taxon>
            <taxon>Lineolatales</taxon>
            <taxon>Lineolataceae</taxon>
            <taxon>Lineolata</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Stud. Mycol." volume="0" first="0" last="0">
            <title>101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens.</title>
            <authorList>
                <person name="Haridas S."/>
                <person name="Albert R."/>
                <person name="Binder M."/>
                <person name="Bloem J."/>
                <person name="Labutti K."/>
                <person name="Salamov A."/>
                <person name="Andreopoulos B."/>
                <person name="Baker S."/>
                <person name="Barry K."/>
                <person name="Bills G."/>
                <person name="Bluhm B."/>
                <person name="Cannon C."/>
                <person name="Castanera R."/>
                <person name="Culley D."/>
                <person name="Daum C."/>
                <person name="Ezra D."/>
                <person name="Gonzalez J."/>
                <person name="Henrissat B."/>
                <person name="Kuo A."/>
                <person name="Liang C."/>
                <person name="Lipzen A."/>
                <person name="Lutzoni F."/>
                <person name="Magnuson J."/>
                <person name="Mondo S."/>
                <person name="Nolan M."/>
                <person name="Ohm R."/>
                <person name="Pangilinan J."/>
                <person name="Park H.-J."/>
                <person name="Ramirez L."/>
                <person name="Alfaro M."/>
                <person name="Sun H."/>
                <person name="Tritt A."/>
                <person name="Yoshinaga Y."/>
                <person name="Zwiers L.-H."/>
                <person name="Turgeon B."/>
                <person name="Goodwin S."/>
                <person name="Spatafora J."/>
                <person name="Crous P."/>
                <person name="Grigoriev I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 16933</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MU001676">
        <property type="protein sequence ID" value="KAF2459023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6A6P6F9"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000799766">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF27">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G15730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="tran
[file cut: first 33554432 bytes kept]
[document cut: first 30728524 of 33554432 characters kept]
